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Conserved domains on  [gi|300388180|ref|NP_001177965|]
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triple QxxK/R motif-containing protein [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TRIQK super family cl21033
Triple QxxK/R motif-containing protein family; TRIQK member-proteins share a characteriztic ...
 1-52 5.43e-25

Triple QxxK/R motif-containing protein family; TRIQK member-proteins share a characteriztic triple repeat of the sequence QXXK/R, as well as a hydrophobic C-terminal region. Xenopus and mouse triqk genes are broadly expressed throughout embryogenesis, and mtriqk is also generally expressed in mouse adult tissues. TRIQK proteins are localized to the endoplasmic reticulum membrane. This family is found in eukaryotes and members are typically between and 86 amino acids in length.


The actual alignment was detected with superfamily member pfam15168:

Pssm-ID: 464542  Cd Length: 79  Bit Score: 88.72  E-value: 5.43e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 300388180   1 MGRKDAATIKLPVDQYRKQIGKQDYKKTKPILRATKLKAEAKKTAIGIKEVG 52
Cdd:pfam15168  1 MGKKDASATKLPVDQYRKQIGKQDYKKTKPVLKATRLKAEAKKSAIGIRDVL 52
 
Name Accession Description Interval E-value
TRIQK pfam15168
Triple QxxK/R motif-containing protein family; TRIQK member-proteins share a characteriztic ...
 1-52 5.43e-25

Triple QxxK/R motif-containing protein family; TRIQK member-proteins share a characteriztic triple repeat of the sequence QXXK/R, as well as a hydrophobic C-terminal region. Xenopus and mouse triqk genes are broadly expressed throughout embryogenesis, and mtriqk is also generally expressed in mouse adult tissues. TRIQK proteins are localized to the endoplasmic reticulum membrane. This family is found in eukaryotes and members are typically between and 86 amino acids in length.


Pssm-ID: 464542  Cd Length: 79  Bit Score: 88.72  E-value: 5.43e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 300388180   1 MGRKDAATIKLPVDQYRKQIGKQDYKKTKPILRATKLKAEAKKTAIGIKEVG 52
Cdd:pfam15168  1 MGKKDASATKLPVDQYRKQIGKQDYKKTKPVLKATRLKAEAKKSAIGIRDVL 52
 
Name Accession Description Interval E-value
TRIQK pfam15168
Triple QxxK/R motif-containing protein family; TRIQK member-proteins share a characteriztic ...
 1-52 5.43e-25

Triple QxxK/R motif-containing protein family; TRIQK member-proteins share a characteriztic triple repeat of the sequence QXXK/R, as well as a hydrophobic C-terminal region. Xenopus and mouse triqk genes are broadly expressed throughout embryogenesis, and mtriqk is also generally expressed in mouse adult tissues. TRIQK proteins are localized to the endoplasmic reticulum membrane. This family is found in eukaryotes and members are typically between and 86 amino acids in length.


Pssm-ID: 464542  Cd Length: 79  Bit Score: 88.72  E-value: 5.43e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 300388180   1 MGRKDAATIKLPVDQYRKQIGKQDYKKTKPILRATKLKAEAKKTAIGIKEVG 52
Cdd:pfam15168  1 MGKKDASATKLPVDQYRKQIGKQDYKKTKPVLKATRLKAEAKKSAIGIRDVL 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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