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Conserved domains on  [gi|301336134|ref|NP_001180380|]
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protein O-mannosyl-transferase TMTC1 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 487-739 2.25e-44

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 161.82  E-value: 2.25e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 487 YNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTR---DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEK 563
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRrrgEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 564 KEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAI 643
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 644 KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELrLA 722
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDyLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-LA 250

                        250
                 ....*....|....*..
gi 301336134 723 LAQVLAVMGQTKEAEKM 739
Cdd:COG2956  251 LADLLERKEGLEAALAL 267
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 623-878 7.21e-39

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 146.03  E-value: 7.21e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 623 GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEE 701
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDpDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 702 ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLK 781
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 782 PKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLkE 861
Cdd:COG2956  175 PDCARALLLL----AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-L 249

                        250
                 ....*....|....*..
gi 301336134 862 NLAKLDRLEKRLQEVRE 878
Cdd:COG2956  250 ALADLLERKEGLEAALA 266
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 313-365 7.07e-24

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 95.67  E-value: 7.07e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 301336134  313 RFLTYSYLLAFNVWLLLAPVTLCYDWQVGSIPLVETIWDMRNLATIFLAVVMA 365
Cdd:pfam08409  23 RTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 487-739 2.25e-44

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 161.82  E-value: 2.25e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 487 YNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTR---DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEK 563
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRrrgEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 564 KEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAI 643
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 644 KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELrLA 722
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDyLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-LA 250

                        250
                 ....*....|....*..
gi 301336134 723 LAQVLAVMGQTKEAEKM 739
Cdd:COG2956  251 LADLLERKEGLEAALAL 267
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 623-878 7.21e-39

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 146.03  E-value: 7.21e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 623 GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEE 701
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDpDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 702 ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLK 781
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 782 PKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLkE 861
Cdd:COG2956  175 PDCARALLLL----AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-L 249

                        250
                 ....*....|....*..
gi 301336134 862 NLAKLDRLEKRLQEVRE 878
Cdd:COG2956  250 ALADLLERKEGLEAALA 266
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 469-875 7.09e-33

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 137.14  E-value: 7.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:TIGR02917 315 YQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAylaLGDFEKAAEYLAKATELDP 394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  546 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVF 625
Cdd:TIGR02917 395 ENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAI 474

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  626 LVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA--HKAEILSpLGALYYNTGRYEEAL 703
Cdd:TIGR02917 475 YLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDpkNLRAILA-LAGLYLRTGNEEEAV 553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  704 QIYQEAAALQPSQRELRLALAQVLAVMGQTKeaekmtnhivseetgclecyrllsaiyskqenhdKALDAIDKALQLKPK 783
Cdd:TIGR02917 554 AWLEKAAELNPQEIEPALALAQYYLGKGQLK----------------------------------KALAILNEAADAAPD 599

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  784 DPkvisELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENL 863
Cdd:TIGR02917 600 SP----EAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGL 675

                         410
                  ....*....|..
gi 301336134  864 AKLDRLEKRLQE 875
Cdd:TIGR02917 676 AQLLLAAKRTES 687
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 313-365 7.07e-24

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 95.67  E-value: 7.07e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 301336134  313 RFLTYSYLLAFNVWLLLAPVTLCYDWQVGSIPLVETIWDMRNLATIFLAVVMA 365
Cdd:pfam08409  23 RTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 495-856 3.26e-14

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 77.05  E-value: 3.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  495 DQGRNKEAIYHYRTALKLYPRHASALNNLG-TLTR--DTAEAKMYYQRALQLHPQHnralFNLG---NLLKSQekkeeai 568
Cdd:PRK11447  281 DSGQGGKAIPELQQAVRANPKDSEALGALGqAYSQqgDRARAVAQFEKALALDPHS----SNRDkweSLLKVN------- 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  569 tllkdsiKYGPEFADAYSSLasllaEQERFKEAEEIYQTGIKNCPDSSdlhnnYGVF-LVDTGLPEK----AVAHYQQAI 643
Cdd:PRK11447  350 -------RYWLLIQQGDAAL-----KANNLAQAERLYQQARQVDNTDS-----YAVLgLGDVAMARKdyaaAERYYQQAL 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  644 KLSPSHHVAMVNLGRLYR------------SLG---ENSMAEewYKRALQVAhkaeILSPLGALYYNTGRYEEALQIYQE 708
Cdd:PRK11447  413 RMDPGNTNAVRGLANLYRqqspekalafiaSLSasqRRSIDD--IERSLQND----RLAQQAEALENQGKWAQAAELQRQ 486

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  709 AAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLEcYRLLSAIYSKQENHDKALDAIDKALQ-------LK 781
Cdd:PRK11447  487 RLALDPGSVWLTYRLAQDLRQAGQRSQADALMRRLAQQKPNDPE-QVYAYGLYLSGSDRDRAALAHLNTLPraqwnsnIQ 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  782 PKDPKVISELFFTKGNQLREQ-------NLLDKAFESYRVAVQLnPDQAQAwmnmggiqhiKGKYVSARAYYERALQLVP 854
Cdd:PRK11447  566 ELAQRLQSDQVLETANRLRDSgkeaeaeALLRQQPPSTRIDLTL-ADWAQQ----------RGDYAAARAAYQRVLTREP 634


                  ..
gi 301336134  855 DS 856
Cdd:PRK11447  635 GN 636
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 587-791 1.79e-13

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 72.28  E-value: 1.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 587 SLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSH-HVAMVNLGRLyrSLGE 665
Cdd:cd24142    5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQL--SGGE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 666 NSMaeEWYKRALQVAhkaeilsplgalyyntgryEEALQIYQEAAALQPSQR-ELRLALAQVLAVMG---QT-----KEA 736
Cdd:cd24142   83 EAL--QYYEKGIEIL-------------------EEELQALQAASAEAEEEAeELKRKLSSALCALAeiyMTdlcdePDA 141

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 737 EKMTNHIVSEETGC----LECYRLLSAIYSKQENHDKALDAIDKALQL-KPKDPKVISEL 791
Cdd:cd24142  142 EQRCEELITKALELdptnPEALQTLASLRISQQRPDEAKEALRRSLELwKDLKEEDEEEA 201
TPR_19 pfam14559
Tetratricopeptide repeat;
697-760 3.67e-09

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 53.74  E-value: 3.67e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 301336134  697 GRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAI 760
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
pgaA PRK10049
outer membrane protein PgaA; Provisional
 693-804 1.63e-07

outer membrane protein PgaA; Provisional


Pssm-ID: 236644 [Multi-domain]  Cd Length: 765  Bit Score: 55.11  E-value: 1.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 693 YYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLEcYRLLSAIYSKQENHDKALD 772
Cdd:PRK10049  59 YRNLKQWQNSLTLWQKALSLEPQNDDYQRGLILTLADAGQYDEALVKAKQLVSGAPDKAN-LLALAYVYKRAGRHWDELR 137

                         90       100       110
                 ....*....|....*....|....*....|...
gi 301336134 773 AIDKALQLKPKDPKVISELFFT-KGNQLREQNL 804
Cdd:PRK10049 138 AMTQALPRAPQTQQYPTEYVQAlRNNRLSAPAL 170
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 764-879 3.93e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.47  E-value: 3.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 764 QENHDKALDAIDKALQLKPKDPKVIsELFftkGNQLREQNLLDKAFESYRVAVQLNPDQ-AQAWMNMGgiQHIKGKyvSA 842
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEAL-ELL---GEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLG--QLSGGE--EA 84

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 301336134 843 RAYYERALQLVpdSKLLKENLAKLDRLEKRLQEVREK 879
Cdd:cd24142   85 LQYYEKGIEIL--EEELQALQAASAEAEEEAEELKRK 119
TPR_1 pfam00515
Tetratricopeptide repeat;
823-855 1.72e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.33  E-value: 1.72e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 301336134  823 AQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 855
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 501-672 4.20e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 44.14  E-value: 4.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 501 EAIYHYRTALkLYPRHASALNNLGTLTRDTAEAKmYYQRALQL----------------HPQHNRALFNLGNLLKSQEKK 564
Cdd:NF040586 544 REVLRRRRRV-LGPDHPRTLLSANNLARDLRELG-RYAEALDLleealeryrevlggpdHPDTLRAAKSLAVALRRAGRL 621

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 565 EEAITLLKDSI-----KYGPEFADAYS---SLASLLAEQERFKEAEEIYQTGIKNCPDSSDLH--------NNYGVFLVD 628
Cdd:NF040586 622 EEALELAEDTYeryrrRFGPDHPDTLAaalSLANDLRALGDADEARELAREVLDRYRRVLGEDhpftlacrNNLAVLLRA 701

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 301336134 629 TGLPEKAVAHYQQAI-----KLSPSHH---VAMVNLGRLYRSLGENSMAEEW 672
Cdd:NF040586 702 LGDPEEARELAEAALeglreRLGPDHPytlAAAVNLANDLAALGDLDAALGE 753
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 630-736 5.97e-04

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 41.13  E-value: 5.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134   630 GLPEKAVAHYQQAIklspshhvamvnlgRLYR--SLGENSmAEEW---YKRALQvAHKAEILSPLGALYYNTGRYEEALQ 704
Cdd:smart01043  19 ADPEAALALLEAAL--------------ALYRgpLLADVP-DEDWaeaERERLR-ELRLEALEALAEALLALGRHEEALA 82

                           90       100       110
                   ....*....|....*....|....*....|..
gi 301336134   705 IYQEAAALQPSQRELRLALAQVLAVMGQTKEA 736
Cdd:smart01043  83 LLERLLALDPLRERLHRLLMRALYRAGRRAEA 114
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 823-855 6.75e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 6.75e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 301336134   823 AQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 855
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 487-739 2.25e-44

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 161.82  E-value: 2.25e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 487 YNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTR---DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEK 563
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRrrgEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 564 KEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAI 643
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 644 KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELrLA 722
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDyLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-LA 250

                        250
                 ....*....|....*..
gi 301336134 723 LAQVLAVMGQTKEAEKM 739
Cdd:COG2956  251 LADLLERKEGLEAALAL 267
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
510-747 5.06e-41

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 150.93  E-value: 5.06e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 510 LKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYS 586
Cdd:COG0457    1 LELDPDDAEAYNNLGLAyrrLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 587 SLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGEN 666
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 667 SMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSE 746
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240


                 .
gi 301336134 747 E 747
Cdd:COG0457  241 Y 241
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 471-713 1.01e-40

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 151.04  E-value: 1.01e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 471 LFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQH 547
Cdd:COG2956   30 LLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDylkAGLLDRAEELLEKLLELDPDD 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 548 NRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLV 627
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 628 DTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQ 707
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLE 269


                 ....*.
gi 301336134 708 EAAALQ 713
Cdd:COG2956  270 RQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 526-779 2.27e-39

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 147.18  E-value: 2.27e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 526 LTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIY 605
Cdd:COG2956   20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 606 QTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAE 684
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDpDCAR 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 685 ILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVsEETGCLECYRLLSAIYSKQ 764
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL-ELDPSDDLLLALADLLERK 258

                        250
                 ....*....|....*
gi 301336134 765 ENHDKALDAIDKALQ 779
Cdd:COG2956  259 EGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 552-810 3.82e-39

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 146.80  E-value: 3.82e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 552 FNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGL 631
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 632 PEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAA 710
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGpENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 711 ALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVI-- 788
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLal 251

                        250       260
                 ....*....|....*....|..
gi 301336134 789 SELFFTKGNQLREQNLLDKAFE 810
Cdd:COG2956  252 ADLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
480-712 4.79e-39

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 145.53  E-value: 4.79e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 480 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRALFNLGN 556
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAylrLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 557 LLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAV 636
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEAL 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 301336134 637 AHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAAL 712
Cdd:COG0457  165 ELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 623-878 7.21e-39

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 146.03  E-value: 7.21e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 623 GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEE 701
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDpDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 702 ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLK 781
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 782 PKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLkE 861
Cdd:COG2956  175 PDCARALLLL----AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL-L 249

                        250
                 ....*....|....*..
gi 301336134 862 NLAKLDRLEKRLQEVRE 878
Cdd:COG2956  250 ALADLLERKEGLEAALA 266
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 501-725 1.29e-33

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 138.20  E-value: 1.29e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 501 EAIYHYRTALKLYPRHASALNNLGtltrDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPE 580
Cdd:COG3914   69 AAAAALLLLAALLELAALLLQALG----RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 581 FADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLY 660
Cdd:COG3914  145 FAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL 224

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301336134 661 RSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQ 725
Cdd:COG3914  225 RQACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAAAAPELPPPP 289
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 469-875 7.09e-33

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 137.14  E-value: 7.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:TIGR02917 315 YQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAylaLGDFEKAAEYLAKATELDP 394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  546 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVF 625
Cdd:TIGR02917 395 ENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAI 474

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  626 LVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA--HKAEILSpLGALYYNTGRYEEAL 703
Cdd:TIGR02917 475 YLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDpkNLRAILA-LAGLYLRTGNEEEAV 553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  704 QIYQEAAALQPSQRELRLALAQVLAVMGQTKeaekmtnhivseetgclecyrllsaiyskqenhdKALDAIDKALQLKPK 783
Cdd:TIGR02917 554 AWLEKAAELNPQEIEPALALAQYYLGKGQLK----------------------------------KALAILNEAADAAPD 599

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  784 DPkvisELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENL 863
Cdd:TIGR02917 600 SP----EAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGL 675

                         410
                  ....*....|..
gi 301336134  864 AKLDRLEKRLQE 875
Cdd:TIGR02917 676 AQLLLAAKRTES 687
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 480-881 1.65e-30

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 129.43  E-value: 1.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  480 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDT---AEAKMYYQRALQLHPQHNRALFNLGN 556
Cdd:TIGR02917 462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEgnpDDAIQRFEKVLTIDPKNLRAILALAG 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  557 LLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAV 636
Cdd:TIGR02917 542 LYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  637 AHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV-AHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPS 715
Cdd:TIGR02917 622 SSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELkPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPK 701

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  716 QRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLlSAIYSKQENHDKALDAIDKALQLKPKDPKVISELfftk 795
Cdd:TIGR02917 702 AALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKL-HRALLASGNTAEAVKTLEAWLKTHPNDAVLRTAL---- 776

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  796 GNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHiKGKYVSARAYYERALQLVPDskllkeNLAKLDRLEKRLQE 875
Cdd:TIGR02917 777 AELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYL-ELKDPRALEYAERALKLAPN------IPAILDTLGWLLVE 849


                  ....*.
gi 301336134  876 VREKDQ 881
Cdd:TIGR02917 850 KGEADR 855
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
613-852 3.81e-30

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 119.73  E-value: 3.81e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 613 PDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGA 691
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDdAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 692 LYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKAL 771
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEAL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 772 DAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQ 851
Cdd:COG0457  165 ELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244


                 .
gi 301336134 852 L 852
Cdd:COG0457  245 A 245
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 469-678 4.65e-30

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 120.22  E-value: 4.65e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:COG2956   62 IRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIyeqEGDWEKAIEVLERLLKLGP 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 546 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVF 625
Cdd:COG2956  142 ENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 301336134 626 LVDTGLPEKAVAHYQQAIKLSPSHHVAMvNLGRLYRSLGENSMAEEWYKRALQ 678
Cdd:COG2956  222 YEKLGDPEEALELLRKALELDPSDDLLL-ALADLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
643-881 1.15e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 118.19  E-value: 1.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 643 IKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPsqrelrl 721
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDpDDAEALYNLGLAYLRLGRYEEALADYEQALELDP------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 722 alaqvlavmgqtkeaekmtnhivseetGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPkvisELFFTKGNQLRE 801
Cdd:COG0457   74 ---------------------------DDAEALNNLGLALQALGRYEEALEDYDKALELDPDDA----EALYNLGLALLE 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 802 QNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVREKDQ 881
Cdd:COG0457  123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 479-719 2.30e-29

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 124.72  E-value: 2.30e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 479 LPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDT---AEAKMYYQRALQLHPQHNRALFNLG 555
Cdd:COG3914    6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAallALAAGEAAAAAAALLLLAALLELAA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 556 NLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKA 635
Cdd:COG3914   86 LLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 636 VAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQP 714
Cdd:COG3914  166 IAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDpDNADAHSNLLFALRQACDWEVYDRFEELLAALAR 245


                 ....*
gi 301336134 715 SQREL 719
Cdd:COG3914  246 GPSEL 250
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
469-606 3.62e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.03  E-value: 3.62e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:COG0457   28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAlqaLGRYEEALEDYDKALELDP 107

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 301336134 546 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQ 606
Cdd:COG0457  108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 546-678 8.46e-25

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 100.65  E-value: 8.46e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 546 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVF 625
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 301336134 626 LVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQ 678
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 496-738 1.70e-24

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 110.17  E-value: 1.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  496 QGRNKEAIYHYRTALKLYPRHASALNNLG---TLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLK 572
Cdd:TIGR02917 614 AGDLNKAVSSFKKLLALQPDSALALLLLAdayAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAK 693

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  573 DSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFL------------------------VD 628
Cdd:TIGR02917 694 SLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLasgntaeavktleawlkthpndavLR 773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  629 TGLPE---------KAVAHYQQAIKLSPSHHVAMVNLGRLYRSLgENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGR 698
Cdd:TIGR02917 774 TALAElylaqkdydKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLApNIPAILDTLGWLLVEKGE 852

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 301336134  699 YEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEK 738
Cdd:TIGR02917 853 ADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARK 892
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 467-873 5.38e-24

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 108.63  E-value: 5.38e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  467 SRESLFRSGVQTLphnakvhynyanflkDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQL 543
Cdd:TIGR02917  21 SPEELIEAAKSYL---------------QKNKYKAAIIQLKNALQKDPNDAEARFLLGKIylaLGDYAAAEKELRKALSL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  544 HPQHNRALFNLGNLLKSQEKKEEAITLL--------KDSIKY---------------------------GPEFADAYSSL 588
Cdd:TIGR02917  86 GYPKNQVLPLLARAYLLQGKFQQVLDELpgktllddEGAAELlalrglaylglgqlelaqksyeqalaiDPRSLYAKLGL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  589 ASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSM 668
Cdd:TIGR02917 166 AQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  669 AEEWYKRALQVAHKaeilSPLGALY-----YNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHI 743
Cdd:TIGR02917 246 AEKHADALLKKAPN----SPLAHYLkalvdFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  744 VSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISEL---------------FFTKGNQLRE------- 801
Cdd:TIGR02917 322 LKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLgeaylalgdfekaaeYLAKATELDPenaaart 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  802 --------QNLLDKAFESYRVAVQLN----------------------------------PDQAQAWMNMGGIQHIKGKY 839
Cdd:TIGR02917 402 qlgisklsQGDPSEAIADLETAAQLDpelgradlllilsylrsgqfdkalaaakklekkqPDNASLHNLLGAIYLGKGDL 481

                         490       500       510
                  ....*....|....*....|....*....|....
gi 301336134  840 VSARAYYERALQLVPDSKLLKENLAKLDRLEKRL 873
Cdd:TIGR02917 482 AKAREAFEKALSIEPDFFPAAANLARIDIQEGNP 515
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 483-615 5.76e-24

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 98.34  E-value: 5.76e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 483 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRALFNLGNLLK 559
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEIllqLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 301336134 560 SQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDS 615
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 313-365 7.07e-24

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 95.67  E-value: 7.07e-24
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 301336134  313 RFLTYSYLLAFNVWLLLAPVTLCYDWQVGSIPLVETIWDMRNLATIFLAVVMA 365
Cdd:pfam08409  23 RTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYGALA 75
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 628-829 2.70e-23

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 105.85  E-value: 2.70e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 628 DTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGAL----------YYNTG 697
Cdd:COG3914   13 AAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLaallelaallLQALG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 698 RYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKA 777
Cdd:COG3914   93 RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRA 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 301336134 778 LQLKPKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNM 829
Cdd:COG3914  173 LELDPDNAEALNNL----GNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 529-649 2.75e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 93.72  E-value: 2.75e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 529 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTG 608
Cdd:COG4783   19 DYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKA 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 301336134 609 IKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSH 649
Cdd:COG4783   99 LKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 533-728 6.95e-22

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 95.48  E-value: 6.95e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  533 AKMYYQRALQLHPQHNRAlfnlgnllksQEKKEeaitlLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNC 612
Cdd:TIGR02521  31 AKIRVQLALGYLEQGDLE----------VAKEN-----LDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  613 PDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMV--NLGRLYRSLGENSMAEEWYKRALQV-AHKAEILSPL 689
Cdd:TIGR02521  96 PNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIEDPLYPQPARSleNAGLCALKAGDFDKAEKYLTRALQIdPQRPESLLEL 175

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 301336134  690 GALYYNTGRYEEA---LQIYQEAAALQPsqRELRLA--LAQVLA 728
Cdd:TIGR02521 176 AELYYLRGQYKDArayLERYQQTYNQTA--ESLWLGirIARALG 217
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 617-738 5.70e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 89.87  E-value: 5.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 617 DLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYN 695
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDePEARLNLGLALLK 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 301336134 696 TGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEK 738
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 652-784 7.40e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 89.48  E-value: 7.40e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 652 AMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 730
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDpDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 301336134 731 GQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKD 784
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 514-826 1.06e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 97.37  E-value: 1.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 514 PRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGpEFADAYSSLASLLA 593
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAG-EAAAAAAALLLLAA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 594 EQERFKEAeeiyqtgikncpdssdlhnnygvfLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGensmaeewy 673
Cdd:COG3914   80 LLELAALL------------------------LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG--------- 126

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 674 kralqvahkaeilsplgalyyntgRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLEC 753
Cdd:COG3914  127 ------------------------RLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEA 182

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 301336134 754 YRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLldKAFESYRVAVQLNPDQAQAW 826
Cdd:COG3914  183 LNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVY--DRFEELLAALARGPSELSPF 253
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 472-823 2.66e-20

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 96.69  E-value: 2.66e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  472 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGT---LTRDTAEAKMYYQRALQLHPQHN 548
Cdd:TIGR02917 522 FEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQyylGKGQLKKALAILNEAADAAPDSP 601

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  549 RALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVD 628
Cdd:TIGR02917 602 EAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLA 681

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  629 TGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQE 708
Cdd:TIGR02917 682 AKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLASGNTAEAVKTLEA 761

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  709 AAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENhDKALDAIDKALQLKPKDPKVI 788
Cdd:TIGR02917 762 WLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAIL 840

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 301336134  789 SelffTKGNQLREQNLLDKAFESYRVAVQLNPDQA 823
Cdd:TIGR02917 841 D----TLGWLLVEKGEADRALPLLRKAVNIAPEAA 871
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 715-856 5.50e-20

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 87.17  E-value: 5.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 715 SQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPkvisELFFT 794
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP----EARLN 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 301336134 795 KGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDS 856
Cdd:COG4783   78 LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 754-866 3.04e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 84.67  E-value: 3.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 754 YRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQ 833
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL----AEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAA 95

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 301336134 834 HIKGKYVSARAYYERALQLVPDS---KLLKENLAKL 866
Cdd:COG4235   96 FQQGDYAEAIAAWQKLLALLPADapaRLLEASIAEA 131
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 472-594 5.49e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 83.90  E-value: 5.49e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 472 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHN 548
Cdd:COG4235    6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAllaAGDTEEAEELLERALALDPDNP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 301336134 549 RALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYsSLASLLAE 594
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR-LLEASIAE 130
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 669-878 1.01e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.21  E-value: 1.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 669 AEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEET 748
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 749 GCLECYRLLsaiysKQENHDKALDAIDKALQLKPKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMN 828
Cdd:COG3914   81 LELAALLLQ-----ALGRYEEALALYRRALALNPDNAEALFNL----GNLLLALGRLEEALAALRRALALNPDFAEAYLN 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 301336134 829 MGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 878
Cdd:COG3914  152 LGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIA 201
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 634-738 1.64e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 82.36  E-value: 1.64e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 634 KAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYNTGRYEEALQIYQEAAAL 712
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDnADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100
                 ....*....|....*....|....*.
gi 301336134 713 QPSQRELRLALAQVLAVMGQTKEAEK 738
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIA 106
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 501-617 2.83e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 81.98  E-value: 2.83e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 501 EAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKY 577
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAylrLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 301336134 578 GPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSD 617
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
476-644 3.57e-18

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 84.20  E-value: 3.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 476 VQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLG---TLTRDTAEAKMYYQRALQLHPQHNRALF 552
Cdd:COG4785   66 ALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGlayLLLGDYDAALEDFDRALELDPDYAYAYL 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 553 NLGNLLKSQEKKEEAITLLKDSIKYGPEfaDAYSSLASLLAEQE-RFKEAEEiyqtgikncpdssDLHNNYGVFLVDTGL 631
Cdd:COG4785  146 NRGIALYYLGRYELAIADLEKALELDPN--DPERALWLYLAERKlDPEKALA-------------LLLEDWATAYLLQGD 210

                        170
                 ....*....|...
gi 301336134 632 PEKAVAHYQQAIK 644
Cdd:COG4785  211 TEEARELFKLALA 223
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 600-726 4.21e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 81.21  E-value: 4.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 600 EAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV 679
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 301336134 680 AHK-AEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQV 726
Cdd:COG4235   81 DPDnPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
502-711 1.13e-17

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 83.04  E-value: 1.13e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 502 AIYHYRTALKLYPRHASALNNLGT---LTRDTAEAKMYYQRALQLhPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYG 578
Cdd:COG4785   25 LLAALLFAAVLALAIALADLALALaaaALAAAALAAERIDRALAL-PDLAQLYYERGVAYDSLGDYDLAIADFDQALELD 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 579 PEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGR 658
Cdd:COG4785  104 PDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYL 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 301336134 659 LYRSLGENsmaeewykralqvAHKAEILSPLGALYYNTGRYEEALQIYQEAAA 711
Cdd:COG4785  184 AERKLDPE-------------KALALLLEDWATAYLLQGDTEEARELFKLALA 223
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 532-647 1.32e-17

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 80.05  E-value: 1.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 532 EAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKN 611
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 301336134 612 CPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSP 647
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 469-581 1.36e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 80.24  E-value: 1.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:COG4783   24 EALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAllkAGDYDEALALLEKALKLDP 103

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 301336134 546 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEF 581
Cdd:COG4783  104 EHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 529-678 1.83e-17

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 80.39  E-value: 1.83e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 529 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTG 608
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 609 IKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQ 678
Cdd:COG5010   81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 566-680 2.27e-17

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 79.28  E-value: 2.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 566 EAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL 645
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 301336134 646 SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA 680
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
529-614 3.82e-17

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 77.13  E-value: 3.82e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 529 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKdSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTG 608
Cdd:COG3063    7 DLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEALAYLERA 85


                 ....*.
gi 301336134 609 IKNCPD 614
Cdd:COG3063   86 LELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 748-878 6.65e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 78.31  E-value: 6.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 748 TGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPkvisELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWM 827
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARL 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 301336134 828 NMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 878
Cdd:COG4783   77 NLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
591-683 7.92e-17

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 76.36  E-value: 7.92e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 591 LLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAhYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAE 670
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|...
gi 301336134 671 EWYKRALQVAHKA 683
Cdd:COG3063   80 AYLERALELDPSA 92
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
626-718 1.83e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 75.21  E-value: 1.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 626 LVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEwYKRALQVA-HKAEILSPLGALYYNTGRYEEALQ 704
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDpNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|....
gi 301336134 705 IYQEAAALQPSQRE 718
Cdd:COG3063   81 YLERALELDPSALR 94
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
495-580 6.18e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 74.05  E-value: 6.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 495 DQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMyYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLL 571
Cdd:COG3063    4 KLGDLEEAEEYYEKALELDPDNADALNNLGLLlleQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82


                 ....*....
gi 301336134 572 KDSIKYGPE 580
Cdd:COG3063   83 ERALELDPS 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
760-855 7.36e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 73.67  E-value: 7.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 760 IYSKQENHDKALDAIDKALQLKPKDPKVISELfftkGNQLREQNLLDKAfESYRVAVQLNPDQAQAWMNMGGIQHIKGKY 839
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNL----GLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDY 75

                         90
                 ....*....|....*.
gi 301336134 840 VSARAYYERALQLVPD 855
Cdd:COG3063   76 DEALAYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 469-598 1.22e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 81.19  E-value: 1.22e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDT---AEAKMYYQRALQLHP 545
Cdd:COG3914  132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLgrlEEAIAAYRRALELDP 211

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 301336134 546 QHNRALFNLGNLLKSQ------EKKEEAITLLKDSIKYGPEFADAYS---SLASLLAEQERF 598
Cdd:COG3914  212 DNADAHSNLLFALRQAcdwevyDRFEELLAALARGPSELSPFALLYLpddDPAELLALARAW 273
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 489-613 2.95e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 73.84  E-value: 2.95e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 489 YANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGtltrDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAI 568
Cdd:COG5010   33 GANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG----DFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAK 108

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 301336134 569 TLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCP 613
Cdd:COG5010  109 EYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 698-854 4.02e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 73.46  E-value: 4.02e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 698 RYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKA 777
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 301336134 778 LQLKPKDPKVISELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVP 854
Cdd:COG5010   81 LQLDPNNPELYYNL----ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 509-647 2.11e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 71.53  E-value: 2.11e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 509 ALKLYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSL 588
Cdd:COG5010   15 LLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 301336134 589 ASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSP 647
Cdd:COG5010   95 ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 490-714 2.21e-14

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 75.33  E-value: 2.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 490 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAEakmyYQRALQL----------HPQHNRALFNLG--NL 557
Cdd:COG3071   92 AELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGD----WEELLELlpalrkhkalSAEEAQALERRAylGL 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 558 LKSQEKKEEAITL----LKDSIKYGPEFADAYsslASLLAEQERFKEAEEIYQTGIKNCPDSsDLHNNYGvfLVDTGLPE 633
Cdd:COG3071  168 LRQAARDAEALKAlwkaLPRAERRDPELAAAY---ARALIALGDHDEAERLLREALKRQWDP-RLVRLYG--RLQGGDPA 241

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 634 KAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQ 713
Cdd:COG3071  242 KQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALA 321


                 .
gi 301336134 714 P 714
Cdd:COG3071  322 L 322
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 495-856 3.26e-14

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 77.05  E-value: 3.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  495 DQGRNKEAIYHYRTALKLYPRHASALNNLG-TLTR--DTAEAKMYYQRALQLHPQHnralFNLG---NLLKSQekkeeai 568
Cdd:PRK11447  281 DSGQGGKAIPELQQAVRANPKDSEALGALGqAYSQqgDRARAVAQFEKALALDPHS----SNRDkweSLLKVN------- 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  569 tllkdsiKYGPEFADAYSSLasllaEQERFKEAEEIYQTGIKNCPDSSdlhnnYGVF-LVDTGLPEK----AVAHYQQAI 643
Cdd:PRK11447  350 -------RYWLLIQQGDAAL-----KANNLAQAERLYQQARQVDNTDS-----YAVLgLGDVAMARKdyaaAERYYQQAL 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  644 KLSPSHHVAMVNLGRLYR------------SLG---ENSMAEewYKRALQVAhkaeILSPLGALYYNTGRYEEALQIYQE 708
Cdd:PRK11447  413 RMDPGNTNAVRGLANLYRqqspekalafiaSLSasqRRSIDD--IERSLQND----RLAQQAEALENQGKWAQAAELQRQ 486

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  709 AAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLEcYRLLSAIYSKQENHDKALDAIDKALQ-------LK 781
Cdd:PRK11447  487 RLALDPGSVWLTYRLAQDLRQAGQRSQADALMRRLAQQKPNDPE-QVYAYGLYLSGSDRDRAALAHLNTLPraqwnsnIQ 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  782 PKDPKVISELFFTKGNQLREQ-------NLLDKAFESYRVAVQLnPDQAQAwmnmggiqhiKGKYVSARAYYERALQLVP 854
Cdd:PRK11447  566 ELAQRLQSDQVLETANRLRDSgkeaeaeALLRQQPPSTRIDLTL-ADWAQQ----------RGDYAAARAAYQRVLTREP 634


                  ..
gi 301336134  855 DS 856
Cdd:PRK11447  635 GN 636
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 658-739 4.48e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 70.76  E-value: 4.48e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 658 RLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEA 736
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNnPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141


                 ...
gi 301336134 737 EKM 739
Cdd:COG5010  142 KAA 144
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 587-791 1.79e-13

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 72.28  E-value: 1.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 587 SLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSH-HVAMVNLGRLyrSLGE 665
Cdd:cd24142    5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQL--SGGE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 666 NSMaeEWYKRALQVAhkaeilsplgalyyntgryEEALQIYQEAAALQPSQR-ELRLALAQVLAVMG---QT-----KEA 736
Cdd:cd24142   83 EAL--QYYEKGIEIL-------------------EEELQALQAASAEAEEEAeELKRKLSSALCALAeiyMTdlcdePDA 141

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 737 EKMTNHIVSEETGC----LECYRLLSAIYSKQENHDKALDAIDKALQL-KPKDPKVISEL 791
Cdd:cd24142  142 EQRCEELITKALELdptnPEALQTLASLRISQQRPDEAKEALRRSLELwKDLKEEDEEEA 201
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
469-545 2.32e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 66.35  E-value: 2.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIyHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:COG3063   12 EEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELlleLGDYDEALAYLERALELDP 90
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
752-855 2.66e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 69.94  E-value: 2.66e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 752 ECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPkvisELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGG 831
Cdd:COG4785   74 QLYYERGVAYDSLGDYDLAIADFDQALELDPDLA----EAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGI 149

                         90       100
                 ....*....|....*....|....
gi 301336134 832 IQHIKGKYVSARAYYERALQLVPD 855
Cdd:COG4785  150 ALYYLGRYELAIADLEKALELDPN 173
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
557-650 9.27e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 64.81  E-value: 9.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 557 LLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEiYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAV 636
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....
gi 301336134 637 AHYQQAIKLSPSHH 650
Cdd:COG3063   80 AYLERALELDPSAL 93
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 669-782 1.51e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 66.14  E-value: 1.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 669 AEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEET 748
Cdd:COG5010   40 DELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSP 119

                         90       100       110
                 ....*....|....*....|....*....|....
gi 301336134 749 GCLECYRLLSAIYSKQENHDKALDAIDKALQLKP 782
Cdd:COG5010  120 DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 480-738 1.86e-12

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 70.78  E-value: 1.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  480 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPR-------HASALNNLGtltrDTAEAKMYYQRALQLHPQHNRALF 552
Cdd:TIGR00990 328 EKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRvtqsyikRASMNLELG----DPDKAEEDFDKALKLNSEDPDIYY 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  553 NLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLP 632
Cdd:TIGR00990 404 HRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKF 483

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  633 EKAVAHYQQAIKLSPSHHVAMVNLGRLyrsLGENSMAEEW---YKRALQVAHKAEILSP--------LGALYYNTGRYEE 701
Cdd:TIGR00990 484 DEAIEKFDTAIELEKETKPMYMNVLPL---INKALALFQWkqdFIEAENLCEKALIIDPecdiavatMAQLLLQQGDVDE 560

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 301336134  702 ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEK 738
Cdd:TIGR00990 561 ALKLFERAAELARTEGELVQAISYAEATRTQIQVQED 597
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 769-875 3.89e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 64.26  E-value: 3.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 769 KALDAIDKALQLKPKDPkvisELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYER 848
Cdd:COG4235    1 EAIARLRQALAANPNDA----EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLER 76

                         90       100
                 ....*....|....*....|....*..
gi 301336134 849 ALQLVPDSKLLKENLAKLDRLEKRLQE 875
Cdd:COG4235   77 ALALDPDNPEALYLLGLAAFQQGDYAE 103
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 799-878 4.07e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 64.98  E-value: 4.07e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 799 LREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 878
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 469-545 1.11e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.83  E-value: 1.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHP 545
Cdd:COG5010   74 LALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALllsLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
571-851 1.82e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 64.55  E-value: 1.82e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 571 LKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNcPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPShh 650
Cdd:COG4785   29 LLFAAVLALAIALADLALALAAAALAAAALAAERIDRALAL-PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPD-- 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 651 vamvnlgrlyrslgensMAEEWYKRalqvahkaeilsplGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 730
Cdd:COG4785  106 -----------------LAEAYNNR--------------GLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 731 GQTKEAEkmtnhivseetgclecyrllsaiyskqenhdkalDAIDKALQLKPKDPKVISELFFTKGnqlreqnlldkafe 810
Cdd:COG4785  155 GRYELAI----------------------------------ADLEKALELDPNDPERALWLYLAER-------------- 186

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 301336134 811 syrvavQLNPDQAQAWMNM--GGIQHIKGKYVSARAYYERALQ 851
Cdd:COG4785  187 ------KLDPEKALALLLEdwATAYLLQGDTEEARELFKLALA 223
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 480-875 2.06e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 67.70  E-value: 2.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  480 PHNAKVHYNYANFLKDQGRNKEAIYHYrTALKLYP--RHASALNNLGTLTRDTAEAKMyyQRALQLHPQHNRALFNLGNL 557
Cdd:TIGR00990 191 PDYSKALNRRANAYDGLGKYADALLDL-TASCIIDgfRNEQSAQAVERLLKKFAESKA--KEILETKPENLPSVTFVGNY 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  558 LKSQeKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQ---ERFKEAEEIYQTGIkncpDSSDL-------HNNYGVFLV 627
Cdd:TIGR00990 268 LQSF-RPKPRPAGLEDSNELDEETGNGQLQLGLKSPESkadESYEEAARAFEKAL----DLGKLgekeaiaLNLRGTFKC 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  628 DTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRAL-QVAHKAEILSPLGALYYNTGRYEEALQIY 706
Cdd:TIGR00990 343 LKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALkLNSEDPDIYYHRAQLHFIKGEFAQAGKDY 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  707 QEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPK-DP 785
Cdd:TIGR00990 423 QKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKEtKP 502

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  786 KVIS---------ELFFTKGNQLREQNLLDKAfesyrvaVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQL--VP 854
Cdd:TIGR00990 503 MYMNvlplinkalALFQWKQDFIEAENLCEKA-------LIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAELarTE 575

                         410       420
                  ....*....|....*....|.
gi 301336134  855 DSKLLKENLAKLDRLEKRLQE 875
Cdd:TIGR00990 576 GELVQAISYAEATRTQIQVQE 596
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
692-783 3.83e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.18  E-value: 3.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 692 LYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMtNHIVSEETGCLECYRLLSAIYSKQENHDKAL 771
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 301336134 772 DAIDKALQLKPK 783
Cdd:COG3063   80 AYLERALELDPS 91
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 496-824 5.36e-11

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 66.65  E-value: 5.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  496 QGRNKEAIYHYRTALKLYPRHASALNNLGTLT---RDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQ--EKKEEAITL 570
Cdd:PRK11447  364 ANNLAQAERLYQQARQVDNTDSYAVLGLGDVAmarKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQspEKALAFIAS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  571 LKDSIKygPEFADAYSSL--------ASLLAEQERFKEAEEIYQTGIKNCPDS--------SDLHNN------------- 621
Cdd:PRK11447  444 LSASQR--RSIDDIERSLqndrlaqqAEALENQGKWAQAAELQRQRLALDPGSvwltyrlaQDLRQAgqrsqadalmrrl 521

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  622 -------------YGVFLVDTGLPEKAVAHYQQ-------------AIKLSPSHHVAMVNlgRLyRSLGENSMAEEWYKR 675
Cdd:PRK11447  522 aqqkpndpeqvyaYGLYLSGSDRDRAALAHLNTlpraqwnsniqelAQRLQSDQVLETAN--RL-RDSGKEAEAEALLRQ 598

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  676 alQVAhKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYR 755
Cdd:PRK11447  599 --QPP-STRIDLTLADWAQQRGDYAAARAAYQRVLTREPGNADARLGLIEVDIAQGDLAAARAQLAKLPATANDSLNTQR 675

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 301336134  756 LLSAIYSKQENHDKALDAIDK-ALQLKPKDPKVISELFFTKGNQLREQNLL-DKAFESYR---VAVQLNPDQAQ 824
Cdd:PRK11447  676 RVALAWAALGDTAAAQRTFNRlIPQAKSQPPSMESALVLRDAARFEAQTGQpQQALETYKdamVASGITPTRPQ 749
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 528-616 1.87e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 58.85  E-value: 1.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 528 RDTAEAKMYYQRALQLHPQHN---RALFNLGNLLKSQEKKEEAITLLKDSIKYGPE---FADAYSSLASLLAEQERFKEA 601
Cdd:COG1729    7 GDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDKA 86

                         90
                 ....*....|....*
gi 301336134 602 EEIYQTGIKNCPDSS 616
Cdd:COG1729   87 RATLEELIKKYPDSE 101
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 496-739 2.04e-10

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 63.01  E-value: 2.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 496 QGRNKEAIYHYRTALKLYPRHASAlnnlgtltRDTAEAKMYYQ------------RALQLHPQHNRALFNLGNLLKSQEK 563
Cdd:COG3071   63 LGDYERRDEYLAQALELAPEAELA--------VLLTRAELLLDqgqaeqalatleALRAGAPRHPQVLRLLLQAYRQLGD 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 564 KEEAITLLKDSIKYGPEFADAYSSLAsLLAEQERFKEA---EEIYQTGIKNCPDS----SDLHNNYGVFLVDTGLPEKAV 636
Cdd:COG3071  135 WEELLELLPALRKHKALSAEEAQALE-RRAYLGLLRQAardAEALKALWKALPRAerrdPELAAAYARALIALGDHDEAE 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 637 AHYQQAIKLSPSHHvamvnLGRLYRSLGENSmAEEWYKRALQVAHK----AEILSPLGALYYNTGRYEEALQIYQEAAAL 712
Cdd:COG3071  214 RLLREALKRQWDPR-----LVRLYGRLQGGD-PAKQLKRAEKWLKKhpndPDLLLALGRLCLRNQLWGKAREYLEAALAL 287

                        250       260
                 ....*....|....*....|....*..
gi 301336134 713 QPSqRELRLALAQVLAVMGQTKEAEKM 739
Cdd:COG3071  288 RPS-AEAYAELARLLEQLGDPEEAAEH 313
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 480-606 2.63e-10

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 61.58  E-value: 2.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  480 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRAL--QLHPQHNRALFNL 554
Cdd:TIGR02521  62 PDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFlcqQGKYEQAMQQFEQAIedPLYPQPARSLENA 141

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 301336134  555 GNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQ 606
Cdd:TIGR02521 142 GLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARAYLE 193
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
799-878 3.12e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.49  E-value: 3.12e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 799 LREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYyERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 878
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALA 80
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 495-591 3.87e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 58.08  E-value: 3.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 495 DQGRNKEAIYHYRTALKLYPRH---ASALNNLGTL---TRDTAEAKMYYQRALQLHPQHNR---ALFNLGNLLKSQEKKE 565
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAyyaLGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYD 84

                         90       100
                 ....*....|....*....|....*....
gi 301336134 566 EAITLLKDSIKYGP---EFADAYSSLASL 591
Cdd:COG1729   85 KARATLEELIKKYPdseAAKEARARLARL 113
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 763-869 4.89e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 57.69  E-value: 4.89e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 763 KQENHDKALDAIDKALQLKPKDPKVISELFFtKGNQLREQNLLDKAFESYRVAVQLNPD---QAQAWMNMGGIQHIKGKY 839
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNSPLAPDALYW-LGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDY 83

                         90       100       110
                 ....*....|....*....|....*....|
gi 301336134 840 VSARAYYERALQLVPDSKLLKENLAKLDRL 869
Cdd:COG1729   84 DKARATLEELIKKYPDSEAAKEARARLARL 113
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 489-855 6.11e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 62.69  E-value: 6.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  489 YANFLKDQG----RNKE---AIYHYRTALKL------YPRHASALNNLGTLTRDTAEAKmyyqRALQLHPQHNRALFNLG 555
Cdd:TIGR00990 126 YAAKLKEKGnkayRNKDfnkAIKLYSKAIECkpdpvyYSNRAACHNALGDWEKVVEDTT----AALELDPDYSKALNRRA 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  556 NLLKSQEKKEEAITLLKDSIKYGpEFADAYSS--LASLLAEQERFKeAEEIYQTGIKNCPDSSDLHNNYGVFLvdtglPE 633
Cdd:TIGR00990 202 NAYDGLGKYADALLDLTASCIID-GFRNEQSAqaVERLLKKFAESK-AKEILETKPENLPSVTFVGNYLQSFR-----PK 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  634 KAVAHYQQAIKLSPSHHVAMVNLGRlyRSLgeNSMAEEWYKRALQVahkaeilsplgalyyntgrYEEALQiyqeaaalq 713
Cdd:TIGR00990 275 PRPAGLEDSNELDEETGNGQLQLGL--KSP--ESKADESYEEAARA-------------------FEKALD--------- 322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  714 psqrelrlalaqvlavMGQTKEAEKmtnhIVSEETGCLECYRllsaiyskqENHDKALDAIDKALQLKPKdpkvISELFF 793
Cdd:TIGR00990 323 ----------------LGKLGEKEA----IALNLRGTFKCLK---------GKHLEALADLSKSIELDPR----VTQSYI 369

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 301336134  794 TKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 855
Cdd:TIGR00990 370 KRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPD 431
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 532-780 1.85e-09

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 59.95  E-value: 1.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 532 EAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPE-FADAYSSLASLLAEqerfKEAEEIYQTGIK 610
Cdd:cd24142   18 LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLGQLSGG----EEALQYYEKGIE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 611 NCpdssdlhnnygvflvdtglpEKAVAHYQQAIKLSPSHHVAMVN-LGRLYRSLGENSMA------------EEWYKRAL 677
Cdd:cd24142   94 IL--------------------EEELQALQAASAEAEEEAEELKRkLSSALCALAEIYMTdlcdepdaeqrcEELITKAL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 678 QVAHK-AEILSPLGALYYNTGRYEEALQIYQEAAAL---------------------QPSqRELRLALAQVLAVMGQTKE 735
Cdd:cd24142  154 ELDPTnPEALQTLASLRISQQRPDEAKEALRRSLELwkdlkeedeeeaeedeaeeedVPS-YEFRISLAKLLIELEMYEE 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 301336134 736 AEKMTNHIVSEETGCLE-------CYRLLS--AIYSKQENHDKALDAIDKALQL 780
Cdd:cd24142  233 ALEVLEQLLDEDDEDVEvwyllgwAYYLLGekEQEEAAELLRDARELLEKALKL 286
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
764-856 2.37e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.39  E-value: 2.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 764 QENHDKALDAIDKALQLKPKDPKVIsELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSAR 843
Cdd:COG4785   49 AAAALAAAALAAERIDRALALPDLA-QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAAL 127

                         90
                 ....*....|...
gi 301336134 844 AYYERALQLVPDS 856
Cdd:COG4785  128 EDFDRALELDPDY 140
TPR_19 pfam14559
Tetratricopeptide repeat;
697-760 3.67e-09

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 53.74  E-value: 3.67e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 301336134  697 GRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAI 760
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 807-878 3.89e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 3.89e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 301336134 807 KAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 878
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEE 72
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 529-780 6.92e-09

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 58.48  E-value: 6.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  529 DTAEAKMYYQRALQLHP--QHNR---ALFNLG-------NLLKSQEKKEEAITLLKDsIKYGPEFADAYSSLASLLAEQE 596
Cdd:pfam17874  16 DAERALELAEQALALLPedDLLArglATFVLGeaylclgDLDAALQAMREAEALARR-ADSPHVTLWALLQQGEILRAQG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  597 RFKEAEEIYQTGIKNCPDSS--------DLHNNYGVFLVDTGLPEKAVAHYQQAIKL----SPSHHV-AMVNLGRLYRSL 663
Cdd:pfam17874  95 RLHQALETYQQALQLARDHGlqhlplhgFLLVGLADLLYEWNDLEEAEQHAQQGIQLgrqwEPDAAVdAYVLLARIALAQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  664 GENSMAEEWYKRALQVAHKAEILSPLGA-------LYY----NTGRYEEALQiyqeaAALQPS-------QRELRLaLAQ 725
Cdd:pfam17874 175 GELEEALTLLRRAELLARQSFFHVDWLAnaervrvRLWlargDLRAAVRWLR-----AAEPPSdadnhflERELRN-LAR 248

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 301336134  726 VLAVMGQTKEAEKMTN--HIVSEETG----CLECYRLLSAIYSKQENHDKALDAIDKALQL 780
Cdd:pfam17874 249 VLLALGRFDDALSLLErlQNLAEQLGrvrsLIENLILQALALLALGRPDEALQALLDALSL 309
TPR_12 pfam13424
Tetratricopeptide repeat;
652-715 9.33e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 52.77  E-value: 9.33e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 301336134  652 AMVNLGRLYRSLGENSMAEEWYKRALQVAHK---------AEILSPLGALYYNTGRYEEALQIYQEAAALQPS 715
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRllgpdhpltATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0790
TPR repeat [General function prediction only];
489-712 9.98e-09

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 56.86  E-value: 9.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 489 YANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL-------TRDTAEAKMYYQR-ALQLHPqhnRALFNLGNLLKS 560
Cdd:COG0790   35 AAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMyaegrgvPKDYEKALEWFEKaAEQGDA---EAQYNLGLMYEE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 561 ----QEKKEEAITLLKDSIKYGpeFADAYSSLASLlaeqerfkeaeeiYQTGIKNCPDssdlhnnygvflvdtglPEKAV 636
Cdd:COG0790  112 glgvPQDYAKALEWYEKAAEQG--DADAQYNLGLL-------------YLNGEGVPKD-----------------PAKAA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 637 AHYQQAIKLSpsHHVAMVNLGRLYRSlGE-----NSMAEEWYKRALQVAHkAEILSPLGALYYN----TGRYEEALQIYQ 707
Cdd:COG0790  160 EWYRKAAEQG--DADAQYNLGVLYEN-GRgvpkdPAKALEWYRKAAEQGD-ADAQYNLGRLYLNgegvEKDLEKALRWLR 235


                 ....*
gi 301336134 708 EAAAL 712
Cdd:COG0790  236 KAAEQ 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 792-880 1.13e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.05  E-value: 1.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 792 FFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAK------ 865
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQdylkag 90

                         90
                 ....*....|....*.
gi 301336134 866 -LDRLEKRLQEVREKD 880
Cdd:COG2956   91 lLDRAEELLEKLLELD 106
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 626-855 1.52e-08

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 57.23  E-value: 1.52e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 626 LVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGEnsmaeewYKRALQVA---HKAEILSPLGALYYNTGRYEEA 702
Cdd:COG3071   95 LLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGD-------WEELLELLpalRKHKALSAEEAQALERRAYLGL 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 703 L-QIYQEAAALQ-------PSQR---ELRLALAQVLAVMGQTKEAEKMTNHIVSEE--TGCLECYRLLsaiysKQENHDK 769
Cdd:COG3071  168 LrQAARDAEALKalwkalpRAERrdpELAAAYARALIALGDHDEAERLLREALKRQwdPRLVRLYGRL-----QGGDPAK 242

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 770 ALDAIDKALQLKPKDPkvisELFFTKGNQLREQNLLDKAFESYRVAVQLNPDqAQAWMNMGGIQHIKGKYVSARAYYERA 849
Cdd:COG3071  243 QLKRAEKWLKKHPNDP----DLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKA 317


                 ....*.
gi 301336134 850 LQLVPD 855
Cdd:COG3071  318 LALALG 323
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 592-678 1.57e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 53.46  E-value: 1.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 592 LAEQERFKEAEEIYQTGIKNCPDSS---DLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHV---AMVNLGRLYRSLGE 665
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGD 82

                         90
                 ....*....|...
gi 301336134 666 NSMAEEWYKRALQ 678
Cdd:COG1729   83 YDKARATLEELIK 95
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 626-725 2.40e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 52.69  E-value: 2.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 626 LVDTGLPEKAVAHYQQAIKLSPSHHV---AMVNLGRLYRSLGENSMAEEWYKRALQvAHKAEILSP-----LGALYYNTG 697
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLKRYPNSPLapdALYWLGEAYYALGDYDEAAEAFEKLLK-RYPDSPKAPdallkLGLSYLELG 81

                         90       100
                 ....*....|....*....|....*...
gi 301336134 698 RYEEALQIYQEAAALQPSQRELRLALAQ 725
Cdd:COG1729   82 DYDKARATLEELIKKYPDSEAAKEARAR 109
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 457-573 3.10e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 3.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  457 KTVKQNEIWLSREslfrsgvqtlPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLG--TLTRDTAEAK 534
Cdd:TIGR02917 754 EAVKTLEAWLKTH----------PNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAwlYLELKDPRAL 823

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 301336134  535 MYYQRALQLHP-----------------QHNRAL-----------------FNLGNLLKSQEKKEEAITLLKD 573
Cdd:TIGR02917 824 EYAERALKLAPnipaildtlgwllvekgEADRALpllrkavniapeaaairYHLALALLATGRKAEARKELDK 896
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 515-682 1.20e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 54.53  E-value: 1.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 515 RHASALNNLGTLTRDTAEAKMYYQ---RALQLHPqhnRALFNLGNLLKSQEKKEEAITLLKDSIKYG--PEFADAYSSLA 589
Cdd:COG3071  160 ERRAYLGLLRQAARDAEALKALWKalpRAERRDP---ELAAAYARALIALGDHDEAERLLREALKRQwdPRLVRLYGRLQ 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 590 SLLAEqERFKEAEEIyqtgIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVnLGRLYRSLGENSMA 669
Cdd:COG3071  237 GGDPA-KQLKRAEKW----LKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAE-LARLLEQLGDPEEA 310

                        170
                 ....*....|...
gi 301336134 670 EEWYKRALQVAHK 682
Cdd:COG3071  311 AEHYRKALALALG 323
pgaA PRK10049
outer membrane protein PgaA; Provisional
 693-804 1.63e-07

outer membrane protein PgaA; Provisional


Pssm-ID: 236644 [Multi-domain]  Cd Length: 765  Bit Score: 55.11  E-value: 1.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 693 YYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLEcYRLLSAIYSKQENHDKALD 772
Cdd:PRK10049  59 YRNLKQWQNSLTLWQKALSLEPQNDDYQRGLILTLADAGQYDEALVKAKQLVSGAPDKAN-LLALAYVYKRAGRHWDELR 137

                         90       100       110
                 ....*....|....*....|....*....|...
gi 301336134 773 AIDKALQLKPKDPKVISELFFT-KGNQLREQNL 804
Cdd:PRK10049 138 AMTQALPRAPQTQQYPTEYVQAlRNNRLSAPAL 170
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 481-614 1.94e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 53.76  E-value: 1.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 481 HNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRH--ASALNNLGTLTRDTAEAKMyyQRALQLHPQHNRALFNLGNLL 558
Cdd:COG3071  191 RDPELAAAYARALIALGDHDEAERLLREALKRQWDPrlVRLYGRLQGGDPAKQLKRA--EKWLKKHPNDPDLLLALGRLC 268

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 301336134 559 KSQEKKEEAITLLKDSIKYGPEfADAYSSLASLLAEQERFKEAEEIYQTGIKNCPD 614
Cdd:COG3071  269 LRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
TPR_12 pfam13424
Tetratricopeptide repeat;
614-680 2.26e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 48.92  E-value: 2.26e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301336134  614 DSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLS-----PSHH---VAMVNLGRLYRSLGENSMAEEWYKRALQVA 680
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIArrllgPDHPltaTTLLNLGRLYLELGRYEEALELLERALALA 75
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 693-831 3.78e-07

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 50.83  E-value: 3.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 693 YY-------NTGRYEEALQIYQEAAALQ--PSQRelrlalAQVLAVMGqtkeaekmtnhivseetgclecyrllsAIYSK 763
Cdd:PRK02603  38 YYrdgmsaqADGEYAEALENYEEALKLEedPNDR------SYILYNMG---------------------------IIYAS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 764 QENHDKALDAIDKALQLKPKDP---KVISELFFTKGNQLREQ-------NLLDKAFESYRVAVQLNPD---QAQAWMNMG 830
Cdd:PRK02603  85 NGEHDKALEYYHQALELNPKQPsalNNIAVIYHKRGEKAEEAgdqdeaeALFDKAAEYWKQAIRLAPNnyiEAQNWLKTT 164


                 .
gi 301336134 831 G 831
Cdd:PRK02603 165 G 165
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 629-780 4.10e-07

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 53.08  E-value: 4.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  629 TGLPEKAVAHYQQAIKLSPS--HHVAMV---NLGRLYRSLGENSMAEEWYKRALQVAHKAEI-------LSPLGALYYNT 696
Cdd:pfam17874  14 KGDAERALELAEQALALLPEddLLARGLatfVLGEAYLCLGDLDAALQAMREAEALARRADSphvtlwaLLQQGEILRAQ 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  697 GRYEEALQIYQEAAALQPSQRELRL--------ALAQVLAVMGQTKEAE-----------KMTNHIVseetgcLECYRLL 757
Cdd:pfam17874  94 GRLHQALETYQQALQLARDHGLQHLplhgfllvGLADLLYEWNDLEEAEqhaqqgiqlgrQWEPDAA------VDAYVLL 167

                         170       180
                  ....*....|....*....|...
gi 301336134  758 SAIYSKQENHDKALDAIDKALQL 780
Cdd:pfam17874 168 ARIALAQGELEEALTLLRRAELL 190
TPR_12 pfam13424
Tetratricopeptide repeat;
483-546 5.00e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 48.15  E-value: 5.00e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301336134  483 AKVHYNYANFLKDQGRNKEAIYHYRTALKLY--------PRHASALNNLGTLTR---DTAEAKMYYQRALQLHPQ 546
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLelgRYEEALELLERALALAEK 77
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
580-708 7.01e-07

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 51.42  E-value: 7.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 580 EFADAYSS---LASLLAEQERFKEAEEIYQTGIK-NCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSP---SHHVA 652
Cdd:COG4700   84 EFADTVQNrvrLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPdfkSSDAH 163

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 301336134 653 MVnLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQE 708
Cdd:COG4700  164 LL-YARALEALGDLEAAEAELEALARRYSGPEARYRYAKFLARQGRTAEAKELLEE 218
TPR_12 pfam13424
Tetratricopeptide repeat;
683-783 8.56e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.38  E-value: 8.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  683 AEILSPLGALYYNTGRYEEALQIYQEAAALQpsqrelrlalaqvlavmgqtkEAEKMTNHIvseetGCLECYRLLSAIYS 762
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIA---------------------RRLLGPDHP-----LTATTLLNLGRLYL 56

                          90       100
                  ....*....|....*....|.
gi 301336134  763 KQENHDKALDAIDKALQLKPK 783
Cdd:pfam13424  57 ELGRYEEALELLERALALAEK 77
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 467-614 8.63e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 52.68  E-value: 8.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  467 SRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKL-------YPRHASALNNLGTLTR---DTAEAKMY 536
Cdd:TIGR00990 451 SSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELeketkpmYMNVLPLINKALALFQwkqDFIEAENL 530

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 301336134  537 YQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSikygPEFADAYSSLASLLAeqerFKEAEEIYQTGIKNCPD 614
Cdd:TIGR00990 531 CEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERA----AELARTEGELVQAIS----YAEATRTQIQVQEDYPV 600
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 549-649 1.23e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 48.06  E-value: 1.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 549 RALFNLGNLlksqekkEEAITLLKDSIKYGPE---FADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSS---DLHNNY 622
Cdd:COG1729    1 KALLKAGDY-------DEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKL 73

                         90       100
                 ....*....|....*....|....*..
gi 301336134 623 GVFLVDTGLPEKAVAHYQQAIKLSPSH 649
Cdd:COG1729   74 GLSYLELGDYDKARATLEELIKKYPDS 100
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 477-821 1.58e-06

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 52.01  E-value: 1.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  477 QTLPHNAKVHYNYANFLKDQGRNKEAIyhyrTALKLYPRHASAlnnlgtltRDTAeAKMYYQ--RALQLHPQHNRAL--- 551
Cdd:PRK11447  175 ADYPGNTGLRNTLALLLFSSGRRDEGF----AVLEQMAKSPAG--------RDAA-AQLWYGqiKDMPVSDASVAALqky 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  552 ---FNLGNLL-KSQEKKEEAITLLKDsikygPEFADAYSSLAslLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLV 627
Cdd:PRK11447  242 lqvFSDGDSVaAARSQLAEQQKQLAD-----PAFRARAQGLA--AVDSGQGGKAIPELQQAVRANPKDSEALGALGQAYS 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  628 DTGLPEKAVAHYQQAIKLSPSHHvamvNLGRlYRSLGENSMaeewYKRALQVAHKAeilspLGAlyyntGRYEEALQIYQ 707
Cdd:PRK11447  315 QQGDRARAVAQFEKALALDPHSS----NRDK-WESLLKVNR----YWLLIQQGDAA-----LKA-----NNLAQAERLYQ 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  708 EAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYsKQENHDKALDAIDkalQLKPKDPKV 787
Cdd:PRK11447  376 QARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPGNTNAVRGLANLY-RQQSPEKALAFIA---SLSASQRRS 451

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 301336134  788 ISEL--------FFTKGNQLREQNLLDKAFESYRVAVQLNPD 821
Cdd:PRK11447  452 IDDIerslqndrLAQQAEALENQGKWAQAAELQRQRLALDPG 493
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 490-604 2.13e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 50.70  E-value: 2.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 490 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMYYQRALQLHPQHN-RALFNLG---------- 555
Cdd:cd24142    7 AEELLDQGNFELALKFLQRALELEPNNVEALELLGEIlleLGDVEEAREVLLRAIELDPDGGyEKYLYLGqlsggeealq 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 556 ----------NLLKSQEKK---------------------------------EEA----ITLLKDSIKYGPEFADAYSSL 588
Cdd:cd24142   87 yyekgieileEELQALQAAsaeaeeeaeelkrklssalcalaeiymtdlcdePDAeqrcEELITKALELDPTNPEALQTL 166

                        170
                 ....*....|....*.
gi 301336134 589 ASLLAEQERFKEAEEI 604
Cdd:cd24142  167 ASLRISQQRPDEAKEA 182
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 469-550 2.77e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.91  E-value: 2.77e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 469 ESLFRSGVQTLPHN---AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRH---ASALNNLGTL---TRDTAEAKMYYQR 539
Cdd:COG1729   13 IAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSyleLGDYDKARATLEE 92

                         90
                 ....*....|.
gi 301336134 540 ALQLHPQHNRA 550
Cdd:COG1729   93 LIKKYPDSEAA 103
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 659-739 5.06e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.14  E-value: 5.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 659 LYRSlGENSMAEEWYKRALQV----AHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQR---ELRLALAQVLAVMG 731
Cdd:COG1729    3 LLKA-GDYDEAIAAFKAFLKRypnsPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELG 81


                 ....*...
gi 301336134 732 QTKEAEKM 739
Cdd:COG1729   82 DYDKARAT 89
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 598-688 1.01e-05

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 46.59  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 598 FKEAEEIYQTGIK---NCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSM------ 668
Cdd:PRK02603  51 YAEALENYEEALKleeDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEKAEeagdqd 130

                         90       100
                 ....*....|....*....|.
gi 301336134 669 -AEEWYKRALQVAHKAEILSP 688
Cdd:PRK02603 131 eAEALFDKAAEYWKQAIRLAP 151
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 762-865 1.41e-05

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 46.20  E-value: 1.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 762 SKQENHD--KALDAIDKALQLKpKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGK- 838
Cdd:PRK02603  44 SAQADGEyaEALENYEEALKLE-EDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEk 122

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 301336134 839 -------------YVSARAYYERALQLVPDSKLLKENLAK 865
Cdd:PRK02603 123 aeeagdqdeaealFDKAAEYWKQAIRLAPNNYIEAQNWLK 162
TPR_12 pfam13424
Tetratricopeptide repeat;
517-576 1.51e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.92  E-value: 1.51e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 301336134  517 ASALNNLGTLTR---DTAEAKMYYQRALQL--------HPQHNRALFNLGNLLKSQEKKEEAITLLKDSIK 576
Cdd:pfam13424   3 ATALNNLAAVLRrlgRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALA 73
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
 529-725 1.74e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 48.35  E-value: 1.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 529 DTAEAKMYYQRALQLHPQH---NRALFNLgnllKSQEKK-EEAITLLKDSIKYGPEFADAYSSL-ASLLAEQERfkEAEE 603
Cdd:COG3898  167 DTEAALALAEEALALAPKLpwaQDALLEL----QAAAGDwDGALATLDAALKAGLLDKDVARRRrAVLLTARAR--ELEE 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 604 iyqtgikncpdssdlhnnygvflvdtGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENsmaeewyKRALQVAHKA 683
Cdd:COG3898  241 --------------------------GDPDEARELAIEALKLAPDLVPAAVLAARLLIAQGKL-------RKAAKVLEKA 287

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 301336134 684 EILSP---LGALYYNTGRYEEALQIYQEA---AALQPSQRELRLALAQ 725
Cdd:COG3898  288 WRAQPhpdLAAAYAELRPGDSALDRLKRAetlAALNPDHPESRLALAE 335
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 632-739 1.80e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 47.88  E-value: 1.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 632 PEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQ--VAHKAEILSPLGALYYNTGRYEEALQIYQEA 709
Cdd:PRK11788 196 LDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEqdPEYLSEVLPKLMECYQALGDEAEGLEFLRRA 275

                         90       100       110
                 ....*....|....*....|....*....|
gi 301336134 710 AALQPSQrELRLALAQVLAVMGQTKEAEKM 739
Cdd:PRK11788 276 LEEYPGA-DLLLALAQLLEEQEGPEAAQAL 304
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 613-868 2.74e-05

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 48.16  E-value: 2.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  613 PDSSDLHNNYGVFLVDTGLPEKAVAHYQQaiklspshhVAMVNLGRlyrslgeNSMAEEWYKralQVahKAEILSPLG-- 690
Cdd:PRK11447  178 PGNTGLRNTLALLLFSSGRRDEGFAVLEQ---------MAKSPAGR-------DAAAQLWYG---QI--KDMPVSDASva 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  691 ALYYNTGRYEEALQIYQEAAALQPSQREL-------RL-ALAQVLAvmGQTKEAEKMTNHIVSEETGCLECYRLLSAIYS 762
Cdd:PRK11447  237 ALQKYLQVFSDGDSVAAARSQLAEQQKQLadpafraRAqGLAAVDS--GQGGKAIPELQQAVRANPKDSEALGALGQAYS 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  763 KQENHDKALDAIDKALQLKPKDPKvISE-----------LFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGG 831
Cdd:PRK11447  315 QQGDRARAVAQFEKALALDPHSSN-RDKwesllkvnrywLLIQQGDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGD 393

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 301336134  832 IQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDR 868
Cdd:PRK11447  394 VAMARKDYAAAERYYQQALRMDPGNTNAVRGLANLYR 430
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
486-607 2.81e-05

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 46.41  E-value: 2.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 486 HYNYANFLKDQGRNKEAIYHYRTALK-LYPRHASALNNLG---TLTRDTAEAKMYYQRALQLHPQHNR--ALFNLGNLLK 559
Cdd:COG4700   92 RVRLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAqalFELGRYAEALETLEKLIAKNPDFKSsdAHLLYARALE 171

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 301336134 560 SQEKKEEAITLLKDSIKYGPeFADAYSSLASLLAEQERFKEAEEIYQT 607
Cdd:COG4700  172 ALGDLEAAEAELEALARRYS-GPEARYRYAKFLARQGRTAEAKELLEE 218
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 632-870 3.05e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 47.11  E-value: 3.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 632 PEKAVAHYQQAIKLSPS---HHVAmvnLGRLYRSLGEnsmaeewYKRALQVaHKAEILSPlgalyyntgryeealqiyqe 708
Cdd:PRK11788  51 PDKAIDLFIEMLKVDPEtveLHLA---LGNLFRRRGE-------VDRAIRI-HQNLLSRP-------------------- 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 709 aaALQPSQREL-RLALAQ-VLAVmGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKD-P 785
Cdd:PRK11788 100 --DLTREQRLLaLQELGQdYLKA-GLLDRAEELFLQLVDEGDFAEGALQQLLEIYQQEKDWQKAIDVAERLEKLGGDSlR 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 786 KVIS----ELfftkGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQ----LVPDS- 856
Cdd:PRK11788 177 VEIAhfycEL----AQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEqdpeYLSEVl 252

                        250
                 ....*....|....
gi 301336134 857 KLLKENLAKLDRLE 870
Cdd:PRK11788 253 PKLMECYQALGDEA 266
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 764-879 3.93e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.47  E-value: 3.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 764 QENHDKALDAIDKALQLKPKDPKVIsELFftkGNQLREQNLLDKAFESYRVAVQLNPDQ-AQAWMNMGgiQHIKGKyvSA 842
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEAL-ELL---GEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLG--QLSGGE--EA 84

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 301336134 843 RAYYERALQLVpdSKLLKENLAKLDRLEKRLQEVREK 879
Cdd:cd24142   85 LQYYEKGIEIL--EEELQALQAASAEAEEEAEELKRK 119
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 552-616 4.81e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.94  E-value: 4.81e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 301336134  552 FNLGNLLKSQEKKEEAITLLKDSIKYG---PEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSS 616
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
654-783 5.74e-05

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 45.64  E-value: 5.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 654 VNLGRLYRSLGENSMAEEWYKRALQ--VAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQR--ELRLALAQVLAV 729
Cdd:COG4700   93 VRLADALLELGRYDEAIELYEEALTgiFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFKssDAHLLYARALEA 172

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 301336134 730 MGQTKEAEKMTNHIVSEETGcLECYRLLSAIYSKQENHDKA---LDAIDKALQLKPK 783
Cdd:COG4700  173 LGDLEAAEAELEALARRYSG-PEARYRYAKFLARQGRTAEAkelLEEILDEAKHMPK 228
TPR_19 pfam14559
Tetratricopeptide repeat;
529-591 5.84e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 41.80  E-value: 5.84e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 301336134  529 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASL 591
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 669-882 6.35e-05

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 45.64  E-value: 6.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 669 AEEWYKRALQvahkaeilsplgalYYNTGRYEEALQIYQEAAALQPSqrelrlalaqvlavmgqTKEAEKMtnhivseet 748
Cdd:COG4105   32 AEELYEEAKE--------------ALEKGDYEKAIKLFEELEPRYPG-----------------SPYAEQA--------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 749 gclecyrLLSAIYS--KQENHDKALDAIDKALQLKPKDPKViSELFFTKG----NQL----REQNLLDKAFESYRVAVQL 818
Cdd:COG4105   72 -------QLMLAYAyyKQGDYEEAIAAADRFIKLYPNSPNA-DYAYYLRGlsyyEQSpdsdRDQTSTRKAIEAFQELINR 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 819 NPD-----QAQAWMNMggIQ--------HI------KGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVREK 879
Cdd:COG4105  144 YPDseyaeDAKKRIDE--LRdklarkelEVaryylkRGAYVAAINRFQNVLEDYPDTPAVEEALYLLVEAYYALGRYDEA 221


                 ...
gi 301336134 880 DQT 882
Cdd:COG4105  222 QDA 224
TPR_14 pfam13428
Tetratricopeptide repeat;
689-726 1.53e-04

Tetratricopeptide repeat;


Pssm-ID: 463874 [Multi-domain]  Cd Length: 44  Bit Score: 40.10  E-value: 1.53e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 301336134  689 LGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQV 726
Cdd:pfam13428   7 LARALLALGDPDEALALLERALALDPDDPEAWLALAQL 44
TPR_11 pfam13414
TPR repeat;
690-731 1.62e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 39.76  E-value: 1.62e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 301336134  690 GALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMG 731
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_1 pfam00515
Tetratricopeptide repeat;
823-855 1.72e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.33  E-value: 1.72e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 301336134  823 AQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 855
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR_11 pfam13414
TPR repeat;
796-837 1.73e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 39.76  E-value: 1.73e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 301336134  796 GNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKG 837
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 483-515 2.20e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.04  E-value: 2.20e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 301336134  483 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPR 515
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_19 pfam14559
Tetratricopeptide repeat;
565-620 2.50e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.87  E-value: 2.50e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 301336134  565 EEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHN 620
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
TPR_11 pfam13414
TPR repeat;
490-524 3.01e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.99  E-value: 3.01e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 301336134  490 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLG 524
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLG 35
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 501-672 4.20e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 44.14  E-value: 4.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 501 EAIYHYRTALkLYPRHASALNNLGTLTRDTAEAKmYYQRALQL----------------HPQHNRALFNLGNLLKSQEKK 564
Cdd:NF040586 544 REVLRRRRRV-LGPDHPRTLLSANNLARDLRELG-RYAEALDLleealeryrevlggpdHPDTLRAAKSLAVALRRAGRL 621

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 565 EEAITLLKDSI-----KYGPEFADAYS---SLASLLAEQERFKEAEEIYQTGIKNCPDSSDLH--------NNYGVFLVD 628
Cdd:NF040586 622 EEALELAEDTYeryrrRFGPDHPDTLAaalSLANDLRALGDADEARELAREVLDRYRRVLGEDhpftlacrNNLAVLLRA 701

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 301336134 629 TGLPEKAVAHYQQAI-----KLSPSHH---VAMVNLGRLYRSLGENSMAEEW 672
Cdd:NF040586 702 LGDPEEARELAEAALeglreRLGPDHPytlAAAVNLANDLAALGDLDAALGE 753
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 626-680 5.23e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 5.23e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 301336134  626 LVDTGLPEKAVAHYQQAIKL---SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA 680
Cdd:pfam13432   7 ALRAGDYDDAAAALEAALARfpeSPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAA 64
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 689-714 5.32e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.89  E-value: 5.32e-04
                          10        20
                  ....*....|....*....|....*.
gi 301336134  689 LGALYYNTGRYEEALQIYQEAAALQP 714
Cdd:pfam07719   7 LGLAYYKLGDYEEALEAYEKALELDP 32
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 630-736 5.97e-04

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 41.13  E-value: 5.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134   630 GLPEKAVAHYQQAIklspshhvamvnlgRLYR--SLGENSmAEEW---YKRALQvAHKAEILSPLGALYYNTGRYEEALQ 704
Cdd:smart01043  19 ADPEAALALLEAAL--------------ALYRgpLLADVP-DEDWaeaERERLR-ELRLEALEALAEALLALGRHEEALA 82

                           90       100       110
                   ....*....|....*....|....*....|..
gi 301336134   705 IYQEAAALQPSQRELRLALAQVLAVMGQTKEA 736
Cdd:smart01043  83 LLERLLALDPLRERLHRLLMRALYRAGRRAEA 114
TPR_15 pfam13429
Tetratricopeptide repeat;
554-785 6.46e-04

Tetratricopeptide repeat;


Pssm-ID: 433199 [Multi-domain]  Cd Length: 279  Bit Score: 42.73  E-value: 6.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  554 LGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLA-----EQERFKEAEEIYQTGIKNCPDSSDLhnnygVFLVD 628
Cdd:pfam13429  14 LATLLYGQGDPRKALAALKEGAQTAPASDTEFWRTLADLAwalqqDDDARRAYRQLLASGKARADDYERL-----ILLLY 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  629 TGLPEKAVA-------------HYQQAIKLSPSHHvAMVNLGRLYRSLGENSMAEE----WYKRAlqvahkaeilsplgA 691
Cdd:pfam13429  89 DARPKDAARlselgwrrfrsprHLYSALYLYERAG-DYDRLARLLASLEELPAAEQspafWLARA--------------E 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  692 LYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKAL 771
Cdd:pfam13429 154 YYRQTGEPDAALRDYRRALALAPASTELRAALLWFLIDLGRRAELRPALAAWRARAETDADLWGPLAAAYLRLGRPRKAL 233

                         250
                  ....*....|....
gi 301336134  772 DAIDKALQLKPKDP 785
Cdd:pfam13429 234 PYLRKQAASNRNDP 247
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 549-648 6.68e-04

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 40.34  E-value: 6.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  549 RALFNLGNLLKSQEKKEEAITLLKDSIKYGPEF---ADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSS---DLHNNY 622
Cdd:TIGR02795   1 EAYYDAALLVLKAGDYADAIQAFQAFLKKYPKStyaPNAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSPkapDALLKL 80

                          90       100
                  ....*....|....*....|....*.
gi 301336134  623 GVFLVDTGLPEKAVAHYQQAIKLSPS 648
Cdd:TIGR02795  81 GMSLQELGDKEKAKATLQQVIKRYPG 106
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 823-855 6.75e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 6.75e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 301336134   823 AQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 855
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 798-878 6.96e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 6.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 798 QLREQNLLDKAFESYRVAVQLNPD---QAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQ 874
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELG 81


                 ....
gi 301336134 875 EVRE 878
Cdd:COG1729   82 DYDK 85
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 793-856 7.16e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.86  E-value: 7.16e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 301336134  793 FTKGNQLREQNLLDKAFESYRVAVQLN---PDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDS 856
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 469-519 8.00e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.37  E-value: 8.00e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 301336134 469 ESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASA 519
Cdd:COG4235   71 EELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
FAT pfam02259
FAT domain; The FAT domain is named after FRAP, ATM and TRRAP.
 460-649 8.05e-04

FAT domain; The FAT domain is named after FRAP, ATM and TRRAP.


Pssm-ID: 396714 [Multi-domain]  Cd Length: 342  Bit Score: 42.73  E-value: 8.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  460 KQNEIWLSRESLFR-SGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLgtLTRDTAEAKMYYQ 538
Cdd:pfam02259 161 KSGRFSLAEKALLKlLGEDPEEWLPEVVYAYAKYLWPTGEQQEALLKLREFLSCYLQKNGELLSG--LEVINPTNLEEFT 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  539 RALqlhpqhNRALFNLGNLL------KSQEKKEEAITLLKDSIKYGPEFADAYSSLAslLAEQERFKEAEEiyqtgIKNC 612
Cdd:pfam02259 239 ELL------ARCYLLKGKWQaalgqnWAEEKSEEILQAYLLATQFDPSWYKAWHTWA--LFNFEVLRKEEQ-----GKEE 305

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 301336134  613 PDSSDLhnnygvflvdTGLPEKAVAHYQQAIKLSPSH 649
Cdd:pfam02259 306 EGPEDL----------SRYVVPAVEGYLRSLSLSSEN 332
COG3899 COG3899
Predicted ATPase [General function prediction only];
531-728 8.95e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 43.31  E-value: 8.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  531 AEAKMYYQRALQLHPQHN-------------RALFNLGNLLKSQEKKEEAITLL----KDSIKYG--PEFADAYSSLASL 591
Cdd:COG3899   722 AEALRYLERALELLPPDPeeeyrlalllelaEALYLAGRFEEAEALLERALAARalaaLAALRHGnpPASARAYANLGLL 801

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  592 LaeQERFKEAEEIYQTGIK------NCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGE 665
Cdd:COG3899   802 L--LGDYEEAYEFGELALAlaerlgDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAA 879

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 301336134  666 NSMAEEW---YKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLA 728
Cdd:COG3899   880 AAAAAALaaaAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAAL 945
TPR_1 pfam00515
Tetratricopeptide repeat;
483-516 9.42e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 9.42e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 301336134  483 AKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRH 516
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
 496-738 1.03e-03

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 42.28  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  496 QGRNKEAIyhyRTALKLYpRHASALNNLGTLTRDTAEAKMyyqralqLHPQHNRALFNLGNLLKSQEKKEEAITLLKD-- 573
Cdd:TIGR00540 164 APRHTAVL---RLALRAY-QRSGNWDALLKLLPALRKAKA-------LSPEEAARLEQQAYIGLLDEAREEDADALKTww 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  574 -----SIKYGPEFADAYsslASLLAEQERFKEAEEIYQTGIKNCPDSsDLHNNYGvfLVDTGLPEKAVAhyqqaiklsps 648
Cdd:TIGR00540 233 kqlprAERQEPELAVAA---AEALIQLGDHDEAEKLIEEALKKEWDP-ELLRLYG--RLQPGDPSPLIK----------- 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  649 hhvamvnlgrlyrslgensMAEEWYKRAlqvAHKAEILSPLGALYYNTGRYEEAlQIYQEAAALQPSQRELRLALAQVLA 728
Cdd:TIGR00540 296 -------------------RAEKWLKKH---PDDALLLLALGRLCLRQQLWGKA-QSYLEASLSLAPTEEAHLELAQLFE 352

                         250
                  ....*....|
gi 301336134  729 VMGQTKEAEK 738
Cdd:TIGR00540 353 QLGDTEAAAQ 362
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 752-784 1.03e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 1.03e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 301336134   752 ECYRLLSAIYSKQENHDKALDAIDKALQLKPKD 784
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 689-715 1.16e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 1.16e-03
                           10        20
                   ....*....|....*....|....*..
gi 301336134   689 LGALYYNTGRYEEALQIYQEAAALQPS 715
Cdd:smart00028   7 LGNAYLKLGDYDEALEYYEKALELDPN 33
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 656-875 1.16e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 42.20  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 656 LGRLYRSLGEnsMAEEWYKRALQVAHKAEILSPLGALYY--------NTGRYEEALQIYQEAAALQPSQRELR-LALAQV 726
Cdd:COG3071   17 LAALLEGLLA--LAEGRYARAEKLLSKAAEHSEAPLLAYllaaraaqALGDYERRDEYLAQALELAPEAELAVlLTRAEL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 727 LAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELfftkgNQLREQNLLD 806
Cdd:COG3071   95 LLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQAL-----ERRAYLGLLR 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 807 KAFESYRV----------AVQLNPD----QAQAWMNMGgiqhikgKYVSARAYYERALQLVPDSKLL--------KENLA 864
Cdd:COG3071  170 QAARDAEAlkalwkalprAERRDPElaaaYARALIALG-------DHDEAERLLREALKRQWDPRLVrlygrlqgGDPAK 242

                        250
                 ....*....|.
gi 301336134 865 KLDRLEKRLQE 875
Cdd:COG3071  243 QLKRAEKWLKK 253
TPR_1 pfam00515
Tetratricopeptide repeat;
752-784 1.28e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 1.28e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 301336134  752 ECYRLLSAIYSKQENHDKALDAIDKALQLKPKD 784
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 823-855 1.34e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 1.34e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 301336134  823 AQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 855
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
COG3899 COG3899
Predicted ATPase [General function prediction only];
469-728 1.38e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 42.54  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  469 ESLFRSGVQTLPHNAKVHYNY------ANFLKDQGRNKEAIYHYRTALKLY-------------PRHASALNNLGTLTR- 528
Cdd:COG3899   725 LRYLERALELLPPDPEEEYRLalllelAEALYLAGRFEEAEALLERALAARalaalaalrhgnpPASARAYANLGLLLLg 804

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  529 DTAEAKMYYQRALQLHPQHN------RALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLA---SLLAEQERFK 599
Cdd:COG3899   805 DYEEAYEFGELALALAERLGdrrleaRALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLalaAAAAAAAAAA 884

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  600 EAEEIYQTGIKNCPDSSDLHNNYGvFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV 679
Cdd:COG3899   885 ALAAAAAAAARLLAAAAAALAAAA-AAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAA 963

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 301336134  680 AHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLA 728
Cdd:COG3899   964 AAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAA 1012
TPR_1 pfam00515
Tetratricopeptide repeat;
683-715 1.40e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 1.40e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 301336134  683 AEILSPLGALYYNTGRYEEALQIYQEAAALQPS 715
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
SNAP cd15832
Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the ...
 532-801 1.40e-03

Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the soluble NSF attachment protein (SNAP) family are involved in intracellular membrane trafficking, including vesicular transport between the endoplasmic reticulum and Golgi apparatus. Higher eukaryotes contain three isoforms of SNAPs: alpha, beta, and gamma. Alpha-SNAP is universally present in eukaryotes and acts as an adaptor protein between SNARE (integral membrane SNAP receptor) and NSF for recruitment to the 20S complex. Beta-SNAP is brain-specific and shares high sequence identity (about 85%) with alpha-SNAP. Gamma-SNAP is weakly related (about 20-25% identity) to the two other isoforms, and is ubiquitous. It may help regulate the activity of the 20S complex. The X-ray structures of vertebrate gamma-SNAP and yeast Sec17, a SNAP family member, show similar all-helical structures consisting of an N-terminal extended twisted sheet of four Tetratricopeptide repeat (TPR)-like helical hairpins and a C-terminal helical bundle.


Pssm-ID: 276937 [Multi-domain]  Cd Length: 278  Bit Score: 41.41  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 532 EAKMYYQRALQLHPQHN------RALFNLGNLLKSqEKKEEAITLLKDSIkygpefadaysslaSLLAEQERF------- 598
Cdd:cd15832   50 EAGDAFLKAAECQLKLDskhdaaNAYVEAAKCYKK-VDPQEAVNCLEKAI--------------EIYTEMGRFrqaakhl 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 599 KEAEEIYQTgikncpdssdlhnnygvflvDTGLPEKAVAHYQQAiklspshhvamvnlGRLYRSLGENSMAEEWYKRAlq 678
Cdd:cd15832  115 KEIAELYEN--------------------ELGDLDKAIEAYEQA--------------ADYYEGEGANSLANKCYLKV-- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 679 vahkAEILSPLgalyyntGRYEEALQIYQEAAA-------LQPSQRE-------LRLALAQVLAVmgqTKEAEKMTN--- 741
Cdd:cd15832  159 ----ADLAAQL-------EDYDKAIEIYEQVARsslennlLKYSAKDyflkaglCHLAAGDVVAA---QRALEKYAEldp 224

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 301336134 742 -HIVSEEtgclecYRLLSAIYSKQENHDkaLDAIDKALqlkpKDPKVISELFFTKGNQLRE 801
Cdd:cd15832  225 sFAGSRE------CKLLEDLLEAVEEGD--VEAFTDAV----KEYDSISKLDKWKTTMLLK 273
ycf3 CHL00033
photosystem I assembly protein Ycf3
 760-831 1.63e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 40.38  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134 760 IYSKQENHDKALDAIDKALQLKPKDPK------VI----SELFFTKGNQLREQNLLDKAFESYRVAVQLNPD---QAQAW 826
Cdd:CHL00033  81 IHTSNGEHTKALEYYFQALERNPFLPQalnnmaVIchyrGEQAIEQGDSEIAEAWFDQAAEYWKQAIALAPGnyiEAQNW 160


                 ....*
gi 301336134 827 MNMGG 831
Cdd:CHL00033 161 LKITG 165
TPR_19 pfam14559
Tetratricopeptide repeat;
669-726 1.65e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.56  E-value: 1.65e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 301336134  669 AEEWYKRALQVA-HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQV 726
Cdd:pfam14559   7 ALELLEQALAEDpDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_7 pfam13176
Tetratricopeptide repeat;
652-680 2.02e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 36.36  E-value: 2.02e-03
                          10        20
                  ....*....|....*....|....*....
gi 301336134  652 AMVNLGRLYRSLGENSMAEEWYKRALQVA 680
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALA 29
COG3899 COG3899
Predicted ATPase [General function prediction only];
630-713 2.14e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.77  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  630 GLPEKAVAHYQQAiklspshhvamvnlGRLYRSLGENSMAEEWYKRAL-------QVAHKAEILSPLGALYYNTGRYEEA 702
Cdd:COG3899   699 GERDRAARLLLRA--------------ARRALARGAYAEALRYLERALellppdpEEEYRLALLLELAEALYLAGRFEEA 764

                          90
                  ....*....|.
gi 301336134  703 LQIYQEAAALQ 713
Cdd:COG3899   765 EALLERALAAR 775
TPR-S pfam20308
Tetratricopeptide Repeats-Sensor; This entry represents a sensor domain consisting of 7 TPR ...
 532-656 2.28e-03

Tetratricopeptide Repeats-Sensor; This entry represents a sensor domain consisting of 7 TPR repeats forming a tightly-wound solenoid structure harbouring a deep central pocket. The TPR-S binding pocket is lined with several conserved aromatic and polar residues predicted to bind a NAD+-derived nucleotide in prokaryotic NAD+-derived nucleotide-activated effector conflict systems. It has been acquired at the base of the choanoflagellate-animal lineage as a core component of the ASK signalosome.


Pssm-ID: 466458 [Multi-domain]  Cd Length: 105  Bit Score: 38.41  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  532 EAKMYYQRALQLhPQHNRALFNLGNLL-KSQEKKEEAITLLKDSIKYGPEFADAYSSLASllAEQERFKEAEEiyqtgik 610
Cdd:pfam20308   4 AAVELLEALLAL-PEDARAQEQLALALaRLPGDRDEALDVLEDLIERLGEDPETLGLLGR--IYKRLWLESAE------- 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 301336134  611 ncpDSSDLhnnygvflvdtglpEKAVAHYQQAIKLSPSHHvAMVNL 656
Cdd:pfam20308  74 ---DREAL--------------DQAIEAYRKAFELDPDDY-PGINA 101
Mad3_BUB1_I pfam08311
Mad3/BUB1 homology region 1; Proteins containing this domain are checkpoint proteins involved ...
 560-609 2.41e-03

Mad3/BUB1 homology region 1; Proteins containing this domain are checkpoint proteins involved in cell division. This region has been shown to be essential for the binding of the binding of BUB1 and MAD3 to CDC20p.


Pssm-ID: 462420  Cd Length: 123  Bit Score: 38.67  E-value: 2.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 301336134  560 SQEKKEEAITLLKDSIkyGPEFADAYSSLASLLAEQERFKEAEEIYQTGI 609
Cdd:pfam08311  76 CDDPRDIFQFLYSNGI--GTKLALFYEEWAELLERQGRFKEADEIYQLGI 123
TPR_15 pfam13429
Tetratricopeptide repeat;
577-737 2.47e-03

Tetratricopeptide repeat;


Pssm-ID: 433199 [Multi-domain]  Cd Length: 279  Bit Score: 40.80  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  577 YGPEFADAYSSLASLLAEQERFKEAEeiyqtgikncpDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNL 656
Cdd:pfam13429 117 YLYERAGDYDRLARLLASLEELPAAE-----------QSPAFWLARAEYYRQTGEPDAALRDYRRALALAPASTELRAAL 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301336134  657 GRLYRSLGENsmAEewyKRALQVAHKAEILS------PLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVM 730
Cdd:pfam13429 186 LWFLIDLGRR--AE---LRPALAAWRARAETdadlwgPLAAAYLRLGRPRKALPYLRKQAASNRNDPLWLLAYADALEQA 260


                  ....*..
gi 301336134  731 GQTKEAE 737
Cdd:pfam13429 261 GRADAAW 267
TPR_11 pfam13414
TPR repeat;
555-595 2.47e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 2.47e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 301336134  555 GNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQ 595
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR_11 pfam13414
TPR repeat;
657-697 2.76e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 2.76e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 301336134  657 GRLYRSLGENSMAEEWYKRALQVAHK-AEILSPLGALYYNTG 697
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDnPEAYYNLGLAYYKLG 42
TPR_10 pfam13374
Tetratricopeptide repeat;
652-683 4.16e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.94  E-value: 4.16e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 301336134  652 AMVNLGRLYRSLGENSMAEEWYKRALQVAHKA 683
Cdd:pfam13374   4 SLNNLANALRAQGRYDEAEELLEEALAIRERV 35
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 752-783 4.58e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.58  E-value: 4.58e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 301336134  752 ECYRLLSAIYSKQENHDKALDAIDKALQLKPK 783
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_10 pfam13374
Tetratricopeptide repeat;
683-713 7.30e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.17  E-value: 7.30e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 301336134  683 AEILSPLGALYYNTGRYEEALQIYQEAAALQ 713
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIR 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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