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Conserved domains on  [gi|312176384|ref|NP_001185890|]
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enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 1 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-292 3.85e-97

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 285.93  E-value: 3.85e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 197
Cdd:PLN02600  81 FSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 198 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 277
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 312176384 278 MAAFREKRTPKFVGK 292
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-292 3.85e-97

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 285.93  E-value: 3.85e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 197
Cdd:PLN02600  81 FSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 198 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 277
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 312176384 278 MAAFREKRTPKFVGK 292
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-285 1.61e-77

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 235.83  E-value: 1.61e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 199
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 200 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:COG1024  167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                 ....*.
gi 312176384 280 AFREKR 285
Cdd:COG1024  243 AFLEKR 248
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-231 4.36e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 192.01  E-value: 4.36e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRG 116
Cdd:cd06558    6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:cd06558   85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 312176384 197 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 231
Cdd:cd06558  165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-292 9.53e-56

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 180.63  E-value: 9.53e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384   40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMN 119
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYRENVLDLWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 199
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  200 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 312176384  280 AFREKRTPKFVGK 292
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
39-289 4.44e-33

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 121.88  E-value: 4.44e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384   39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKER------EQMSEAEVGVF-V 111
Cdd:TIGR01929  10 TDGIAKITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRgdygyiDDSGVHRLNVLdV 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  112 QRLrglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIF 191
Cdd:TIGR01929  90 QRQ------IRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKAREIWF 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  192 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQraraLAQEILPQAPIAVRLGKVAIDrgTEVDIASG-MAIEGMCYAQNIP 270
Cdd:TIGR01929 164 LCRQYDAKQALDMGLVNTVVPLADLEKETVR----WCREILQKSPMAIRMLKAALN--ADCDGQAGlQELAGNATMLFYM 237
                         250
                  ....*....|....*....
gi 312176384  271 TRDRLEGMAAFREKRTPKF 289
Cdd:TIGR01929 238 TEEGQEGRNAFLEKRQPDF 256
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-292 3.85e-97

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 285.93  E-value: 3.85e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PLN02600   1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 197
Cdd:PLN02600  81 FSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 198 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 277
Cdd:PLN02600 161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                        250
                 ....*....|....*
gi 312176384 278 MAAFREKRTPKFVGK 292
Cdd:PLN02600 237 LAAFAEKRKPVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
39-292 1.04e-94

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 280.08  E-value: 1.04e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07657  11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK07657  91 EMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 278
Cdd:PRK07657 171 QEAKEIGLVEFVVPAHL----LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGL 246
                        250
                 ....*....|....
gi 312176384 279 AAFREKRTPKFVGK 292
Cdd:PRK07657 247 QAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-285 1.61e-77

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 235.83  E-value: 1.61e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 199
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 200 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:COG1024  167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                 ....*.
gi 312176384 280 AFREKR 285
Cdd:COG1024  243 AFLEKR 248
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
39-292 2.10e-62

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 197.66  E-value: 2.10e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK05809  11 EGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK05809  91 RKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVNHAVAQNEEGDAAYqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 278
Cdd:PRK05809 171 EEALRIGLVNKVVEPEKLMEEAK----ALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGM 246
                        250
                 ....*....|....
gi 312176384 279 AAFREKRTPKFVGK 292
Cdd:PRK05809 247 TAFVEKREKNFKNK 260
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-231 4.36e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 192.01  E-value: 4.36e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA--EVGVFVQRLRG 116
Cdd:cd06558    6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAgeEARAFIRELQE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:cd06558   85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 312176384 197 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 231
Cdd:cd06558  165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
39-292 8.38e-58

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 185.99  E-value: 8.38e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQ-MSEAEVGVFVQRLRGL 117
Cdd:PRK07658   9 EDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIH-GEGRFFSAGADIKEFTSvTEAEQATELAQLGQVT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 197
Cdd:PRK07658  87 FERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPIT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 198 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 277
Cdd:PRK07658 167 GAEALKWGLVNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEG 242
                        250
                 ....*....|....*
gi 312176384 278 MAAFREKRTPKFVGK 292
Cdd:PRK07658 243 VQAFLEKRKPSFSGK 257
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
39-292 7.04e-57

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 183.53  E-value: 7.04e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRgLM 118
Cdd:PRK06688  12 EDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLT-GAGRAFSAGGDIKDFPKAPPKPPDELAPVNR-FL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK06688  90 RAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVNHAVAqNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 278
Cdd:PRK06688 170 EEALRIGLVNRVVP-AAELDAE---ADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGA 245
                        250
                 ....*....|....
gi 312176384 279 AAFREKRTPKFVGK 292
Cdd:PRK06688 246 TAFIEKRKPDFTGF 259
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-292 9.53e-56

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 180.63  E-value: 9.53e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384   40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMN 119
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYRENVLDLWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 199
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  200 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 312176384  280 AFREKRTPKFVGK 292
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
35-292 1.91e-55

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 179.96  E-value: 1.91e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEreqMSEAE-VGVFVQR 113
Cdd:PRK09674   5 LVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVIT-GNARFFAAGADLNE---MAEKDlAATLNDP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 114 LRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTG 193
Cdd:PRK09674  81 RPQLWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 194 RRLSGTEAHVLGLVNHaVAQNEegdAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRD 273
Cdd:PRK09674 161 ESITAQQAQQAGLVSE-VFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATED 236
                        250
                 ....*....|....*....
gi 312176384 274 RLEGMAAFREKRTPKFVGK 292
Cdd:PRK09674 237 RHEGISAFLEKRTPDFKGR 255
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
38-292 2.89e-52

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 171.77  E-value: 2.89e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEreqMSEAE-VGVFVQRLRG 116
Cdd:PRK08138  14 PADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKE---FATAGaIEMYLRHTER 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:PRK08138  90 YWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 197 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLE 276
Cdd:PRK08138 170 PAPEALAIGLVSEVV----EDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKE 245
                        250
                 ....*....|....*.
gi 312176384 277 GMAAFREKRTPKFVGK 292
Cdd:PRK08138 246 GMDAFLEKRKPAYKGK 261
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
45-289 4.61e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 160.98  E-value: 4.61e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVgvFVQRLRGLMNDIAAF 124
Cdd:PRK05862  17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIKEMADLSFMDV--YKGDYITNWEKVARI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 125 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 204
Cdd:PRK05862  94 RKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERA 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 205 GLVNHAVAQNEEGDAAYQRARALAQEILPqapiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREK 284
Cdd:PRK05862 174 GLVSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEK 249

                 ....*
gi 312176384 285 RTPKF 289
Cdd:PRK05862 250 RKPVF 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
39-292 1.19e-47

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 159.82  E-value: 1.19e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGvfvQRLRGLM 118
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWP---ESGFGGL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK06494  88 TSRFDLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTA 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVNHAVAQnEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQN--IPTRDRLE 276
Cdd:PRK06494 168 REGLELGFVNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDYPAVEarRASQDYIE 243
                        250
                 ....*....|....*.
gi 312176384 277 GMAAFREKRTPKFVGK 292
Cdd:PRK06494 244 GPKAFAEKRPPRWKGR 259
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
41-292 1.17e-43

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 149.37  E-value: 1.17e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVgvfvqRLRGLMND 120
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKAFARGERPSI-----PGRGFGGL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 121 IAAFPA-PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 199
Cdd:PRK08252  86 TERPPRkPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAE 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 200 EAHVLGLVNHAVAQNEEGDAayqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:PRK08252 166 RAHELGLVNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGAT 241
                        250
                 ....*....|...
gi 312176384 280 AFREKRTPKFVGK 292
Cdd:PRK08252 242 AFAEKRAPVWTGK 254
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
28-292 1.85e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 149.47  E-value: 1.85e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  28 SEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQM--SEA 105
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESrsDAE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 106 EVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVAL 185
Cdd:PRK06127  87 AVAAYEQAVEAAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSA 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 186 AKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDR----GTEVDIASGMAIE 261
Cdd:PRK06127 167 AKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAG----NAPLTLRAAKRAIAEllkdEPERDMAACQALV 242
                        250       260       270
                 ....*....|....*....|....*....|.
gi 312176384 262 GMCYAqnipTRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK06127 243 AACFD----SEDYREGRAAFMEKRKPVFKGR 269
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
45-287 8.90e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 146.99  E-value: 8.90e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  45 ILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAF 124
Cdd:PRK09076  16 LTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFGEAFEALSAF 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 125 PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 204
Cdd:PRK09076  95 RGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALRI 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 205 GLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREK 284
Cdd:PRK09076 175 GLVEEVVEKGE----AREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLEK 250

                 ...
gi 312176384 285 RTP 287
Cdd:PRK09076 251 RAP 253
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
47-291 1.80e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 146.30  E-value: 1.80e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLRGLMNDIAA 123
Cdd:PRK07511  18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRAIRA 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 124 FPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 203
Cdd:PRK07511  97 FPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 204 LGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 283
Cdd:PRK07511 177 LGVVNRLAEPGQALAEALALADQLAA----GSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLE 252

                 ....*...
gi 312176384 284 KRTPKFVG 291
Cdd:PRK07511 253 KRAPDYKR 260
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
39-292 5.77e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 145.14  E-value: 5.77e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV-FVQRLRGL 117
Cdd:PRK06144  15 RGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVaYERRIDRV 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGL-IETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:PRK06144  95 LGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGAARVKDMLFTARLL 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 197 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAqnipTRDRLE 276
Cdd:PRK06144 175 EAEEALAAGLVNEVV----EDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCYM----SEDFRE 246
                        250
                 ....*....|....*.
gi 312176384 277 GMAAFREKRTPKFVGK 292
Cdd:PRK06144 247 GVEAFLEKRPPKWKGR 262
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
39-290 2.39e-41

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 143.48  E-value: 2.39e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07509  10 EDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRaVIL--SGEGGAFCAGLDVKSVASSPGNAVKLLFKRLPGN 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAF-------PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELI 190
Cdd:PRK07509  88 ANLAQRVslgwrrlPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELT 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 191 FTGRRLSGTEAHVLGLVNHAVaqneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP 270
Cdd:PRK07509 168 YTARVFSAEEALELGLVTHVS------DDPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLL 241
                        250       260
                 ....*....|....*....|
gi 312176384 271 TRDRLEGMAAFREKRTPKFV 290
Cdd:PRK07509 242 GKNQKIAVKAQMKKRAPKFL 261
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
41-289 2.06e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 141.05  E-value: 2.06e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV----FVQRLRG 116
Cdd:PRK05980  12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADValrdFVRRGQA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:PRK05980  92 MTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 197 SGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLE 276
Cdd:PRK05980 172 SAERALEIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLRE 247
                        250
                 ....*....|...
gi 312176384 277 GMAAFREKRTPKF 289
Cdd:PRK05980 248 GLAAWIERRRPAY 260
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
39-292 2.12e-40

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 140.99  E-value: 2.12e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKERE--QMSEAEVGV--F--VQ 112
Cdd:PRK03580  10 NGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAegEAPDADFGPggFagLT 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 113 RLRGLmndiaafPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFT 192
Cdd:PRK03580  89 EIFDL-------DKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMT 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 193 GRRLSGTEAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP-- 270
Cdd:PRK03580 162 GRRMDAEEALRWGIVNRVVPQAELMD----RARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsv 237
                        250       260
                 ....*....|....*....|....
gi 312176384 271 --TRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK03580 238 lhSEDALEGPRAFAEKRDPVWKGR 261
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
39-226 4.09e-40

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 148.12  E-value: 4.09e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQM-SEAEVGVFVQRLRG 116
Cdd:PRK11154  13 EDNIAVITIDVPGEKmNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACkTAQEAEALARQGQQ 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSA--VMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 194
Cdd:PRK11154  93 LFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGK 172
                        170       180       190
                 ....*....|....*....|....*....|..
gi 312176384 195 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARA 226
Cdd:PRK11154 173 QLRAKQALKLGLVDDVVPHSILLEVAVELAKK 204
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
41-283 4.34e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 140.11  E-value: 4.34e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVGVFvqRLRGLMND 120
Cdd:PRK06190  13 RVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVL-TGADPAFCAGLDLKELGGDGSAYGAQD--ALPNPSPA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 121 IAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 200
Cdd:PRK06190  90 WPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAAD 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 201 AHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEgMCYAQNIPTRDRLEGMAA 280
Cdd:PRK06190 170 ALRAGLVTEVVPHDE----LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALE-AEAARAHNRSVSPDGIAA 244

                 ...
gi 312176384 281 FRE 283
Cdd:PRK06190 245 RRE 247
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
27-220 4.29e-38

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 142.31  E-value: 4.29e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  27 GSEIQVRALagpDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKERE---QMS 103
Cdd:PRK11730   5 GKTLQVDWL---EDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSA-KDAFIVGADITEFLslfAAP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 104 EAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGV 183
Cdd:PRK11730  81 EEELSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGA 160
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 312176384 184 ALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAA 220
Cdd:PRK11730 161 DNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAA 197
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
39-291 6.29e-38

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 135.10  E-value: 6.29e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADL-----------KEREQMSEAEV 107
Cdd:PRK06142  13 ADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLpamagvfgqlgKDGLARPRTDL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 108 GVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAK 187
Cdd:PRK06142  92 RREILRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHLR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 188 ELIFTGRRLSGTEAHVLGLVNHAVaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQ 267
Cdd:PRK06142 172 ELALTGRDIDAAEAEKIGLVNRVY---DDADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAA 248
                        250       260
                 ....*....|....*....|....
gi 312176384 268 NIPTRDRLEGMAAFREKRTPKFVG 291
Cdd:PRK06142 249 MLPSKDLTEAIAAHMEKRPPEFTG 272
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
47-292 1.02e-36

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 131.76  E-value: 1.02e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvgvfvqRLRGLMNDIAAFPA 126
Cdd:PRK07799  20 MNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGD------SFKDGSYDPSRIDA 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 127 ---------PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 197
Cdd:PRK07799  93 llkgrrltkPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHIT 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 198 GTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 277
Cdd:PRK07799 173 AAEAKEIGLIGHVVPD----GQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEG 248
                        250
                 ....*....|....*
gi 312176384 278 MAAFREKRTPKFVGK 292
Cdd:PRK07799 249 PRAFAEKRAPNFQGR 263
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
47-292 2.58e-36

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 130.48  E-value: 2.58e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  47 MNRPSARNAL-GNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFP 125
Cdd:PRK09245  18 MNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKDMRARVGAFGGSPADIRQGYRHGIQRIP 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 126 A-------PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK09245  97 LalynlevPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 278
Cdd:PRK09245 177 ATALEWGLVSRVVPA----DQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHREAV 252
                        250
                 ....*....|....
gi 312176384 279 AAFREKRTPKFVGK 292
Cdd:PRK09245 253 DAFLEKRPPVFTGR 266
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
42-292 3.08e-36

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 130.15  E-value: 3.08e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  42 ITEILMNRPSARNALGNVFVSELLETLAQLREDRqVRVLLFRSGVKG-VFCAGADLKEREQMSEAEVGvFVQRLRGLMND 120
Cdd:PRK11423  14 IATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSGGRDPLS-YDDPLRQILRM 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 121 IAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTE 200
Cdd:PRK11423  92 IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 201 AHVLGLVNHaVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEvdiASGMAIEGMCYAQNI-----PTRDRL 275
Cdd:PRK11423 172 ALAVGILNH-VVEVEELEDF---TLQMAHHISEKAPLAIAVIKEQLRVLGE---AHPMNPDEFERIQGLrravyDSEDYQ 244
                        250
                 ....*....|....*..
gi 312176384 276 EGMAAFREKRTPKFVGK 292
Cdd:PRK11423 245 EGMNAFLEKRKPVFVGH 261
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
39-292 7.20e-36

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 129.04  E-value: 7.20e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvGVFVQRLR--- 115
Cdd:PRK06495  11 SDHVAVVTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADLKGRPDVIKGP-GDLRAHNRrtr 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 116 GLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLlpgAGGTQRLPRCLGVALAKELIFTGRR 195
Cdd:PRK06495  88 ECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHSLTRRMMLTGYR 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 196 LSGTEAHVLGLVNHAVAqneeGDAAYQRARALAQEILPQAPIAVRLGKVAIdrgtevDIASGMAI-EGMCYAQNIP---- 270
Cdd:PRK06495 165 VPAAELYRRGVIEACLP----PEELMPEAMEIAREIASKSPLATRLAKDAL------NTIENMSLrDGYRYEQDITakla 234
                        250       260
                 ....*....|....*....|...
gi 312176384 271 -TRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK06495 235 kTEDAKEAQRAFLEKRPPVFKGR 257
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
39-288 1.67e-35

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 128.21  E-value: 1.67e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVL---HGEGDHFCAGLDLSELRERDAGEGMHHSRRWHRVF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK08150  86 DKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMC--YAQNIP-TRDRL 275
Cdd:PRK08150 166 QEGERLGLAQYLVPAGE----ALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMaaVAQSAPeAKERL 241
                        250
                 ....*....|...
gi 312176384 276 egmAAFREKRTPK 288
Cdd:PRK08150 242 ---RAFLEKKAAK 251
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
38-289 2.49e-35

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 128.48  E-value: 2.49e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE----REQMSEAEVGVFVQR 113
Cdd:PLN02664  14 PNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGER 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 114 LR----GLMNDIAAFP---APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALA 186
Cdd:PLN02664  93 LRrkikFLQDAITAIEqcrKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNA 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 187 KELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDaayQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYA 266
Cdd:PLN02664 173 MELALTGRRFSGSEAKELGLVSRVFGSKEDLD---EGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNS 249
                        250       260
                 ....*....|....*....|...
gi 312176384 267 QNIPTRDRLEGMAAFREKRTPKF 289
Cdd:PLN02664 250 AMLVSDDLNEAVSAQIQKRKPVF 272
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
34-285 1.81e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 125.53  E-value: 1.81e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQR 113
Cdd:PRK06143   9 GVTRDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 114 LRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGlLPGAGGTQRLPRCLGVALAKELIFTG 193
Cdd:PRK06143  89 LRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTG 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 194 RRLSGTEAHVLGLVnHAVAQNEEGDAAYQRaraLAQEILPQAPIAVRLGKVAI----DRGTEVDIASGMAIEGMCYAQNI 269
Cdd:PRK06143 168 ETIDAAQALAWGLV-DRVVPLAELDAAVER---LAASLAGCGPQALRQQKRLLreweDMPLDVAIDDSVAEFGAAFLTGE 243
                        250
                 ....*....|....*.
gi 312176384 270 PTRDrlegMAAFREKR 285
Cdd:PRK06143 244 PQRH----MAAFLNRK 255
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
39-292 1.92e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 123.11  E-value: 1.92e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQM---SEAEVGVFVQRLR 115
Cdd:PRK05995  11 RGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMagySDDENRADARRLA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 116 GLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPgaggTQRLP---RCLGVALAKELIFT 192
Cdd:PRK05995  90 DMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 193 GRRLSGTEAHVLGLVNHAVAQnEEGDAAYQrarALAQEILPQAPIAVRLGKVAIDrgtevDIAsGMAIEGMCYAQnipTR 272
Cdd:PRK05995 166 AERFDAAEALRLGLVHEVVPA-EALDAKVD---ELLAALVANSPQAVRAGKRLVR-----DVA-GRPIDAALIAD---TA 232
                        250       260       270
                 ....*....|....*....|....*....|
gi 312176384 273 DRL----------EGMAAFREKRTPKFVGK 292
Cdd:PRK05995 233 SRIalirateearEGVAAFLEKRKPAWRGR 262
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
39-289 4.44e-33

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 121.88  E-value: 4.44e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384   39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKER------EQMSEAEVGVF-V 111
Cdd:TIGR01929  10 TDGIAKITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRgdygyiDDSGVHRLNVLdV 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  112 QRLrglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIF 191
Cdd:TIGR01929  90 QRQ------IRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKAREIWF 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  192 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQraraLAQEILPQAPIAVRLGKVAIDrgTEVDIASG-MAIEGMCYAQNIP 270
Cdd:TIGR01929 164 LCRQYDAKQALDMGLVNTVVPLADLEKETVR----WCREILQKSPMAIRMLKAALN--ADCDGQAGlQELAGNATMLFYM 237
                         250
                  ....*....|....*....
gi 312176384  271 TRDRLEGMAAFREKRTPKF 289
Cdd:TIGR01929 238 TEEGQEGRNAFLEKRQPDF 256
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
39-287 5.20e-33

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 121.97  E-value: 5.20e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEreqMSEAEVGVFVQRLRG-- 116
Cdd:PRK08139  18 RDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKE---MRAARGLAYFRALFArc 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 --LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLL---PGAGgtqrLPRCLGVALAKELIF 191
Cdd:PRK08139  94 srVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEMLL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 192 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAyqraRALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPT 271
Cdd:PRK08139 170 TGEFIDAATAREWGLVNRVVPADALDAAV----ARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMA 245
                        250
                 ....*....|....*.
gi 312176384 272 RDRLEGMAAFREKRTP 287
Cdd:PRK08139 246 EDAEEGIDAFLEKRPP 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
39-292 6.93e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 121.74  E-value: 6.93e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSE------AEVGVFVQ 112
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGELQTIDPsdgrrdTDVRPFVG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 113 RLRGLMNDIAAF----PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKE 188
Cdd:PRK06210  92 NRRPDYQTRYHFltalRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALD 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 189 LIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPqAPIAVRLGKVAIDRGTEVDIASGMAIEGMcyAQN 268
Cdd:PRK06210 172 LLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSP-ASMAVIKRQLYEDAFQTLAEATARANREM--HES 248
                        250       260
                 ....*....|....*....|....
gi 312176384 269 IPTRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK06210 249 LQRPDFIEGVASFLEKRPPRFPGL 272
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
39-288 1.20e-32

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 121.27  E-value: 1.20e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMSEAEVGV------- 109
Cdd:PRK09120  15 EDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLT-GAGDAWSAGMDLKEyfRETDAQPEILQerirrea 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 110 --FVQRLRglmndiaAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAK 187
Cdd:PRK09120  94 ygWWRRLR-------WYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDAL 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 188 ELIFTGRRLSGTEAHVLGLVNHAV--AQNEEgdaayqRARALAQEILPQAPIAVRLGKVAIDRGTEvdiasgmaiegMCY 265
Cdd:PRK09120 167 YYIMTGETFTGRKAAEMGLVNESVplAQLRA------RTRELAAKLLEKNPVVLRAAKDGFKRVRE-----------LTW 229
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 312176384 266 AQNI--------------PTRDRLEGMAAFREKRTPK 288
Cdd:PRK09120 230 DQAEdylyakleqansldPEGGREEGLKQFLDDKSYK 266
PLN02888 PLN02888
enoyl-CoA hydratase
41-288 1.34e-32

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 121.01  E-value: 1.34e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMseaevgvfvqrLRGLMND 120
Cdd:PLN02888  19 GIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIIL-TGSGRAFCSGVDLTAAEEV-----------FKGDVKD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 121 IAAFPA--------PTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFT 192
Cdd:PLN02888  87 VETDPVaqmercrkPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 193 GRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIE---GMCYAQNI 269
Cdd:PLN02888 167 AMPLTAETAERWGLVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEkerAHDYYNGM 242
                        250
                 ....*....|....*....
gi 312176384 270 pTRDRLEGMAAFREKRTPK 288
Cdd:PLN02888 243 -TKEQFQKMQEFIAGRSSK 260
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
36-247 2.02e-31

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 116.48  E-value: 2.02e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  36 AGPDQGITEILMNRPSArNALGNVFVSELLETLAQL-REDRQVRVLLFrsGVKGVFCAGADLKEREQMSEAEVGVFVQRL 114
Cdd:PRK05869  12 GSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELgRRDDVAAVILY--GGHEIFSAGDDMPELRTLSAQEADTAARVR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 115 RGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 194
Cdd:PRK05869  89 QQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGR 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 312176384 195 RLSGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAID 247
Cdd:PRK05869 169 FFDAEEALALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
39-235 3.46e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 114.22  E-value: 3.46e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--REQMSEAEVG----VFVQ 112
Cdd:PRK08259  10 NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVL-WGAGGTFCAGADLKAvgTGRGNRLHPSgdgpMGPS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 113 RLRglmndiaaFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMG---------LIEttrgllpgaGGTQRLPRCLGV 183
Cdd:PRK08259  89 RMR--------LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGvfcrrwgvpLID---------GGTVRLPRLIGH 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 312176384 184 ALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEI--LPQA 235
Cdd:PRK08259 152 SRAMDLILTGRPVDADEALAIGLANRVVPKGQ----ARAAAEELAAELaaFPQT 201
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
39-292 4.32e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 114.24  E-value: 4.32e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAE---VGVFVQRLR 115
Cdd:PRK08140  11 EAGVATLTLNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAGRG-FCAGQDLADRDVTPGGAmpdLGESIETFY 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 116 G-LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 194
Cdd:PRK08140  89 NpLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGE 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 195 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDR 274
Cdd:PRK08140 169 KLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLAT----QPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADY 244
                        250
                 ....*....|....*...
gi 312176384 275 LEGMAAFREKRTPKFVGK 292
Cdd:PRK08140 245 AEGVSAFLEKRAPRFTGR 262
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
39-292 1.89e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 110.48  E-value: 1.89e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL-------------KEREQMSEA 105
Cdd:PRK08260  11 ADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLsaggntfdldaprTPVEADEED 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 106 EVGVFVQRLRG----LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCL 181
Cdd:PRK08260  90 RADPSDDGVRDgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLV 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 182 GVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEilpQAPIAVRLGKVAIDRGTEVDI-ASGMAI 260
Cdd:PRK08260 170 GLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADN---TSPVSVALTRQMMWRMAGADHpMEAHRV 246
                        250       260       270
                 ....*....|....*....|....*....|..
gi 312176384 261 EGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK08260 247 DSRAIYSRGRSGDGKEGVSSFLEKRPAVFPGK 278
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
39-291 4.62e-28

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 108.90  E-value: 4.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEVGVFVQRL 114
Cdd:PRK08258  24 DDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLT-GAGGNFCSGGDVHEiigpLTKMDMPELLAFTRMT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 115 RGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGlLPGA--GGTQRLPRCLGVALAKELIFT 192
Cdd:PRK08258 103 GDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVG-LAGAdmGACALLPRIIGQGRASELLYT 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 193 GRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRgtEVDIASGMAIEGMCYAQNI--P 270
Cdd:PRK08258 182 GRSMSAEEGERWGFFNRLV----EPEELLAEAQALARRLAAGPTFAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcmQ 255
                        250       260
                 ....*....|....*....|.
gi 312176384 271 TRDRLEGMAAFREKRTPKFVG 291
Cdd:PRK08258 256 TEDFRRAYEAFVAKRKPVFEG 276
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-248 9.25e-28

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 112.62  E-value: 9.25e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384   41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK--EREQMSEaEVGVFVQRLRGL 117
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQmiAACKTAQ-EVTQLSQEGQEM 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  118 MNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAA--SSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 195
Cdd:TIGR02441 101 FERIEKSQKPIVAAISGSCLGGGLELALACHYRIATkdRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 312176384  196 LSGTEAHVLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 248
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
39-292 1.91e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 107.04  E-value: 1.91e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKEreQMSEAEVGVFvQRLRGLM 118
Cdd:PRK07659  13 EGRVATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGRG-FSAGGDIKM--MLSSNDESKF-DGVMNTI 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIA----AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 194
Cdd:PRK07659  88 SEIVvtlyTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGK 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 195 RLSGTEAHVLGLVNhAVAQNEEGDAAYQRARALAQEILpQAPIAVRLGKVAIDRGTEVDIasgMAIEGMCYAQNIPTRDR 274
Cdd:PRK07659 168 KLSATEALDLGLID-EVIGGDFQTAAKQKISEWLQKPL-KAMIETKQIYCELNRSQLEQV---LQLEKRAQYAMRQTADH 242
                        250
                 ....*....|....*...
gi 312176384 275 LEGMAAFREKRTPKFVGK 292
Cdd:PRK07659 243 KEGIRAFLEKRLPVFKGE 260
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
45-292 2.13e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 104.27  E-value: 2.13e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRV-LLFRSGvkGVFCAGADLKE--------REQMSEAEVGVF--VQR 113
Cdd:PRK06563  12 IGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVaVLFAHG--EHFTAGLDLADvapklaagGFPFPEGGIDPWgtVGR 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 114 LRGlmndiaafpAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTG 193
Cdd:PRK06563  90 RLS---------KPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 194 RRLSGTEAHVLGLVNHAVAQNEEgdaaYQRARALAQEILPQAPIAVRL----GKVAIDRGTEVDIASGMAIegmcYAQNI 269
Cdd:PRK06563 161 DEFDAQEALRLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtlasARAAVREGEAAAAAQLPPE----LRPLF 232
                        250       260
                 ....*....|....*....|...
gi 312176384 270 PTRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK06563 233 TSEDAKEGVQAFLERRPARFKGR 255
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
41-289 5.67e-26

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 103.43  E-value: 5.67e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQR 113
Cdd:PRK07396  22 GIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRLnvldLQR 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 114 LrglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTG 193
Cdd:PRK07396 102 L------IRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLC 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 194 RRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDrgTEVDIASGMA-IEG---MCYAQni 269
Cdd:PRK07396 176 RQYDAQEALDMGLVNTVVPLADLEKETVRWCR----EMLQNSPMALRCLKAALN--ADCDGQAGLQeLAGnatMLFYM-- 247
                        250       260
                 ....*....|....*....|
gi 312176384 270 pTRDRLEGMAAFREKRTPKF 289
Cdd:PRK07396 248 -TEEAQEGRNAFNEKRQPDF 266
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
35-292 1.96e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 101.67  E-value: 1.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-EREQM--SEAEVGVFV 111
Cdd:PRK07468   8 IAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGwMRAQMtaDRATRIEEA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 112 QRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRcLGVALAKELIF 191
Cdd:PRK07468  87 RRLAMMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFM 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 192 TGRRLSGTEAHVLGLVNHAVAQnEEGDAAYQRARAlaqEILPQAPIAV-RLGKVAIDRGTEVDIAS-GMAIEGMcyAQNI 269
Cdd:PRK07468 166 SARLFDAEEAVRLGLLSRVVPA-ERLDAAVEAEVT---PYLSCAPGAVaAAKALVRALGAPIDEAViDATIEAL--ADTW 239
                        250       260
                 ....*....|....*....|...
gi 312176384 270 PTRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK07468 240 ETEEAREGIAAFFDKRAPAWRGG 262
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
34-289 3.67e-25

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 101.25  E-value: 3.67e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEA-EVGVFVQ 112
Cdd:PRK07327  14 RFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIR-GEGKAFSAGGDLALVEEMADDfEVRARVW 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 113 R-LRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIF 191
Cdd:PRK07327  93 ReARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLL 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 192 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAID---RGTEVDIASGMAIEGMCYAqn 268
Cdd:PRK07327 173 LCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAA----GSQTAIRWTKYALNnwlRMAGPTFDTSLALEFMGFS-- 246
                        250       260
                 ....*....|....*....|.
gi 312176384 269 ipTRDRLEGMAAFREKRTPKF 289
Cdd:PRK07327 247 --GPDVREGLASLREKRAPDF 265
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
39-292 4.15e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 100.48  E-value: 4.15e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRsGVKGVFCAGADLKEREQMSEaevgvFVQRLRGLM 118
Cdd:PRK07854   7 DGQVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLT-GQGTVFCAGADLSGDVYADD-----FPDALIEML 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSG 198
Cdd:PRK07854  80 HAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 199 TEAHVLGLVnhavaqNEEGDAAyqRARALAQEILPQAPIAVRLGKVAI-DRGTEVDIASGmaiEGMCYAQNIPTRDRLEG 277
Cdd:PRK07854 160 EQALATGMA------NRIGTLA--DAQAWAAEIAGLAPLALQHAKRVLnDDGAIEEAWPA---HKELFDKAWASQDAIEA 228
                        250
                 ....*....|....*
gi 312176384 278 MAAFREKRTPKFVGK 292
Cdd:PRK07854 229 QVARIEKRPPKFQGA 243
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
38-229 1.23e-24

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 99.27  E-value: 1.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07110  11 VEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILT-GYPNYFATGGTQEGLLSLQTGKGTFTEANLYSL 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDiaaFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLS 197
Cdd:PRK07110  90 ALN---CPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYR 166
                        170       180       190
                 ....*....|....*....|....*....|..
gi 312176384 198 GTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ 229
Cdd:PRK07110 167 GAELKKRGVPFPVLPRAEVLEKALELARSLAE 198
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
45-211 1.82e-24

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 100.62  E-value: 1.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384   45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-REQMSE---AEVGVFVQRLRGLMN 119
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGaGERA-FCAGGDVRAlYEAAKAgggEAGRDFFREEYRLNY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRC---LGVALAkeliFTGRRL 196
Cdd:pfam16113  83 LIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLpgeLGLYLA----LTGARL 158
                         170
                  ....*....|....*
gi 312176384  197 SGTEAHVLGLVNHAV 211
Cdd:pfam16113 159 NGADALAAGLATHYV 173
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
38-288 5.09e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 98.49  E-value: 5.09e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGvFVQRLRGL 117
Cdd:PRK08290  10 VAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGTPGRDRDPG-PDQHPTLW 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 118 MNDIAAF-----------------------PAPTIAAMDGFALGGGLELALACDLRVAASSAV-------Mgliettrgl 167
Cdd:PRK08290  88 WDGATKPgveqryarewevylgmcrrwrdlPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFfsdpvvrM--------- 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 168 lpGAGGTQRL--PRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVA 245
Cdd:PRK08290 159 --GIPGVEYFahPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDE----LEAETLELARRIAAMPPFGLRLTKRA 232
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 312176384 246 IDRGTEVD-----IASGMAIEGMCYAQN------IPTRDRLEGMAAFREKRTPK 288
Cdd:PRK08290 233 VNQTLDAQgfraaLDAVFDLHQLGHAHNaevggdRLGGADARGMADARKAAAAK 286
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
37-246 9.07e-24

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 96.96  E-value: 9.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  37 GPDQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAEVGVFVQRlrg 116
Cdd:PRK07938   7 TPEPGIAEVTVDYPPV-NALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPGFTALIDANR--- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 lmNDIAAF------PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLprcLGVALAKELI 190
Cdd:PRK07938  82 --GCFAAFravyecAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLQRL---VPQHLMRALF 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 312176384 191 FTGRRLSGTEAHVLGLVnHAVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKVAI 246
Cdd:PRK07938 157 FTAATITAAELHHFGSV-EEVVPRDQLDEA---ALEVARKIAAKDTRVIRAAKEAL 208
PLN02921 PLN02921
naphthoate synthase
39-289 1.18e-23

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 98.32  E-value: 1.18e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFvQRLR--G 116
Cdd:PLN02921  74 GEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKDGYVGPDDA-GRLNvlD 152
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:PLN02921 153 LQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFY 232
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 197 SGTEAHVLGLVNHAV--AQNEEGDAAYQRaralaqEILPQAPIAVRLGKVAIDRGTevDIASGmaIEGMcyAQNIP---- 270
Cdd:PLN02921 233 TASEALKMGLVNTVVplDELEGETVKWCR------EILRNSPTAIRVLKSALNAAD--DGHAG--LQEL--GGNATllfy 300
                        250       260
                 ....*....|....*....|
gi 312176384 271 -TRDRLEGMAAFREKRTPKF 289
Cdd:PLN02921 301 gSEEGNEGRTAYLEGRAPDF 320
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
41-289 2.77e-23

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 96.43  E-value: 2.77e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLF-----RSGVKGVFCAGADLKEREQ---MSEAEVGVF-- 110
Cdd:COG0447   27 GIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLtgngpSKDGGWAFCSGGDQRVRGRggyVYEDGVGRLni 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 111 --VQRLrglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKE 188
Cdd:COG0447  107 leVQRL------IRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFGQTGPDVGSFDAGYGSAYLARQVGQKKARE 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 189 LIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDRGTEvdiasGMAieG------ 262
Cdd:COG0447  181 IWFLCRQYSAQEALEMGLVNKVVPHAELEEEAVEWAR----EILEKSPTAIRMLKAAFNADDD-----GLA--Gqqefag 249
                        250       260       270
                 ....*....|....*....|....*....|.
gi 312176384 263 ----MCYAqnipTRDRLEGMAAFREKRTPKF 289
Cdd:COG0447  250 eatrLAYM----TDEAQEGRDAFLEKRKPDF 276
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
38-290 1.60e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 91.43  E-value: 1.60e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSEAE---VGVFVQRL 114
Cdd:PRK05864  16 PRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSAGVVPHVEgltRPTYALRS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 115 RGLMNDIA----AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGA-GGTQRLPRCLGVALAKEL 189
Cdd:PRK05864  95 MELLDDVIlalrRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASElGLSYLLPRAIGSSRAFEI 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 190 IFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTevdIASGMAIEGMcyAQ-- 267
Cdd:PRK05864 175 MLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAAS---LEAHMQAEGL--GQlf 249
                        250       260
                 ....*....|....*....|....
gi 312176384 268 -NIPTRDRLEGMAAFREKRTPKFV 290
Cdd:PRK05864 250 vRLLTANFEEAVAARAEKRPPVFT 273
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
41-291 1.37e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 88.30  E-value: 1.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEfAPDFAIDLRETFYPIIREIRF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 120 DIAAFpaptIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRcLGVALAKELIFTGRRLSGT 199
Cdd:PRK06072  88 SDKIY----ISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLK-LTGQRFYEILVLGGEFTAE 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 200 EAHVLGLVnhavaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:PRK06072 163 EAERWGLL-------KISEDPLSDAEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGIS 235
                        250
                 ....*....|..
gi 312176384 280 AFREKRTPKFVG 291
Cdd:PRK06072 236 SFKEKREPKFKG 247
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
39-292 2.11e-20

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 88.25  E-value: 2.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDR-QVRVLLFRSGVKGvFCAGADLKER-EQMSEAEVGV------- 109
Cdd:PRK05981  11 DGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgSGGRESDSGGdagaale 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 110 -----FVQRLRGlmndiaaFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVA 184
Cdd:PRK05981  90 tayhpFLRRLRN-------LPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 185 LAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAqeilpQAPiAVRLGKVAIDRGTEVDIASGMAIEGMC 264
Cdd:PRK05981 163 RAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA-----NGP-TVALGLIRKLYWDSPENDFEEQLNLER 236
                        250       260       270
                 ....*....|....*....|....*....|
gi 312176384 265 YAQNIP--TRDRLEGMAAFREKRTPKFVGK 292
Cdd:PRK05981 237 EAQRIAgkTEDFKEGVGAFLQKRPAQFKGR 266
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
39-228 3.00e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 87.47  E-value: 3.00e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEreqMSEAEVGVFVQRLRGLM 118
Cdd:PRK05870  10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADLTA---LGAAPGRPAEDGLRRIY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 N---DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRR 195
Cdd:PRK05870  86 DgflAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMR 165
                        170       180       190
                 ....*....|....*....|....*....|...
gi 312176384 196 LSGTEAHVLGLVNHAVaqNEEGDAAYQRARALA 228
Cdd:PRK05870 166 FDAEAAVRHGLALMVA--DDPVAAALELAAGPA 196
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
39-291 5.73e-20

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 87.04  E-value: 5.73e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLFRSGvkGVFCAGADLKE--REQMSEAEVGVFVQR-L 114
Cdd:PRK07827  13 DGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRaVVLTHTG--GTFCAGADLSEagGGGGDPYDAAVARAReM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 115 RGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIfTGR 194
Cdd:PRK07827  91 TALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYL-TGE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 195 RLSGTEAHVLGLVNHAVAQNEEGDAayqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDR 274
Cdd:PRK07827 170 KFGAAEAARIGLVTAAADDVDAAVA------ALLADLRRGSPQGLAESKALTTAAVLAGFDRDAEELTEESARLFVSDEA 243
                        250
                 ....*....|....*..
gi 312176384 275 LEGMAAFREKRTPKFVG 291
Cdd:PRK07827 244 REGMTAFLQKRPPRWAL 260
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
45-215 1.92e-19

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 86.80  E-value: 1.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-----REQMSEAEVGVFVQRLRgLM 118
Cdd:PRK05617  16 ITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERG-FCAGGDIRAlyeaaRAGDPLAADRFFREEYR-LN 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGvALAKELIFTGRRLSG 198
Cdd:PRK05617  94 ALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPG-ALGTYLALTGARISA 172
                        170
                 ....*....|....*..
gi 312176384 199 TEAHVLGLVNHAVAQNE 215
Cdd:PRK05617 173 ADALYAGLADHFVPSAD 189
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
40-287 2.62e-19

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 85.24  E-value: 2.62e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGVFV---QRLRG 116
Cdd:PRK05674  14 RGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLR-GRGRHFSAGADLAWMQQSADLDYNTNLddaRELAE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:PRK05674  93 LMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAP-AVISPFVVKAIGERAARRYALTAERF 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 197 SGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKvaiDRGTEVDiASGMAIEGMCYAQNIPTRDRL- 275
Cdd:PRK05674 172 DGRRARELGLLAESYPAAE----LEAQVEAWIANLLLNSPQALRASK---DLLREVG-DGELSPALRRYCENAIARIRVs 243
                        250
                 ....*....|....*.
gi 312176384 276 ----EGMAAFREKRTP 287
Cdd:PRK05674 244 aegqEGLRAFLEKRTP 259
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
39-289 6.30e-19

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 84.69  E-value: 6.30e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR----SGVKG--VFCAGADLKER------------- 99
Cdd:PRK08321  32 DQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTgngpSPKDGgwAFCSGGDQRIRgrdgyqyaegdea 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 100 EQMSEAEVGVF----VQRLrglmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASS-AVMGLIETTRGLLPGAGGT 174
Cdd:PRK08321 112 DTVDPARAGRLhileVQRL------IRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGS 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 175 QRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVA---IDRG-T 250
Cdd:PRK08321 186 AYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAR----EINGKSPTAMRMLKYAfnlTDDGlV 261
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 312176384 251 EVDIASGMAIEgMCYAqnipTRDRLEGMAAFREKRTPKF 289
Cdd:PRK08321 262 GQQLFAGEATR-LAYM----TDEAQEGRDAFLEKRDPDW 295
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
31-220 2.61e-17

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 79.96  E-value: 2.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  31 QVRALAGPDQGITEILMnRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR-----SGVKGVFCAGADL--------- 96
Cdd:PRK08788  16 QLRVYYEEERNVMWMYM-RAQPRPCFNLELLDDIMNLQRAIRQRLDDSGLPVDfwvlaSDVPGVFNLGGDLalfaelira 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  97 KEREQMSE-AEVGVfvqrlRGLMNDIAAF--PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGG 173
Cdd:PRK08788  95 GDRDALLAyARACV-----DGVHAFHRGFgaGAISIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGA 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 312176384 174 TQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVnHAVAQNEEGDAA 220
Cdd:PRK08788 170 YSFLARRVGPKLAEELILSGKLYTAEELHDMGLV-DVLVEDGQGEAA 215
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
38-231 5.43e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 79.32  E-value: 5.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-REQMSEAEVGVFVQRLRG 116
Cdd:PRK08272  16 VTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAyAEGSSSGGGGGAYPGKRQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFP------------------------APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIET-TRGLLPGA 171
Cdd:PRK08272  95 AVNHLPDDPwdpmidyqmmsrfvrgfmslwhahKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTrVWGVPATG 174
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 172 GGTQRlprcLGVALAKELIFTGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 231
Cdd:PRK08272 175 MWAYR----LGPQRAKRLLFTGDCITGAQAAEWGLAVEAV----PPEELDERTERLVERI 226
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
39-207 1.04e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 72.08  E-value: 1.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07260   9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 119 NDIA----AFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGR 194
Cdd:PRK07260  88 NEISfaikQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLAMTGE 167
                        170
                 ....*....|...
gi 312176384 195 RLSGTEAHVLGLV 207
Cdd:PRK07260 168 ALTAEKALEYGFV 180
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
39-215 1.41e-14

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 71.64  E-value: 1.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKE-REQMSEAEVGVFVQR-LRG 116
Cdd:PRK07112  11 QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVL---EGLPEVFCFGADFSAiAEKPDAGRADLIDAEpLYD 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 117 LMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPgAGGTQRLPRCLGVALAKELIFTGRRL 196
Cdd:PRK07112  88 LWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP-ACVLPFLIRRIGTQKAHYMTLMTQPV 166
                        170
                 ....*....|....*....
gi 312176384 197 SGTEAHVLGLVNHAVAQNE 215
Cdd:PRK07112 167 TAQQAFSWGLVDAYGANSD 185
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
45-211 3.67e-14

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 71.75  E-value: 3.67e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK-----EREQMSEAEVgvfVQRLRGLMN 119
Cdd:PLN02874  24 ITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIK-GAGRAFSAGGDLKmfydgRESDDSCLEV---VYRMYWLCY 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGvALAKELIFTGRRLSGT 199
Cdd:PLN02874 100 HIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPG-HLGEYLALTGARLNGK 178
                        170
                 ....*....|..
gi 312176384 200 EAHVLGLVNHAV 211
Cdd:PLN02874 179 EMVACGLATHFV 190
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
46-209 8.26e-14

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 71.16  E-value: 8.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  46 LMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGAD-LKEREQMSEA---EVGVFVQRLRGLMNDI 121
Cdd:PLN02851  56 ILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMK-GSGRAFCSGADvVSLYHLINEGnveECKLFFENLYKFVYLQ 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 122 AAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGT---QRLPRCLGVALAkeliFTGRRLSG 198
Cdd:PLN02851 135 GTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASyylSRLPGYLGEYLA----LTGQKLNG 210
                        170
                 ....*....|.
gi 312176384 199 TEAHVLGLVNH 209
Cdd:PLN02851 211 VEMIACGLATH 221
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
41-281 1.08e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 69.05  E-value: 1.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEReqMSEAEVGV-FVQRLRGLMN 119
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFL-GTEGCFSAGNDMQDF--LAAAMGGTsFGSEILDFLI 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 120 DIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGT 199
Cdd:PRK06023  92 ALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAE 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 200 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIdRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 279
Cdd:PRK06023 172 AAQEAGLIWKIVDE----EAVEAETLKAAEELAAKPPQALQIARDLM-RGPREDILARIDEEAKHFAARLKSAEARAAFE 246

                 ..
gi 312176384 280 AF 281
Cdd:PRK06023 247 AF 248
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
20-229 1.08e-13

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 69.52  E-value: 1.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  20 ASDGAAGGSEIQVRAlagpdQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGV-KGVFCAGADLKE 98
Cdd:PLN03214   5 SPPGATPGVRVDRRP-----GGIAVVWLAKEPV-NSMTLAMWRSLDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAE 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  99 --REQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGL-LPGAGGTQ 175
Cdd:PLN03214  79 lyAPKTSAARYAEFWLTQTTFLVRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARL 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 312176384 176 RLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQ 229
Cdd:PLN03214 159 FMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALK 212
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
31-211 8.02e-13

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 67.82  E-value: 8.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  31 QVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADL----KEREQMSEAE 106
Cdd:PLN02988   8 QSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILK-GHGRAFCAGGDVaavvRDIEQGNWRL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 107 VGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVaLA 186
Cdd:PLN02988  87 GANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FG 165
                        170       180
                 ....*....|....*....|....*
gi 312176384 187 KELIFTGRRLSGTEAHVLGLVNHAV 211
Cdd:PLN02988 166 EYVGLTGARLDGAEMLACGLATHFV 190
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
46-215 4.81e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 65.86  E-value: 4.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  46 LMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEVGVFVQRLRGLMNDI 121
Cdd:PLN02157  51 ILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMK-GSGRAFCAGGDIVSlyhlRKRGSPDAIREFFSSLYSFIYLL 129
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 122 AAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGvALAKELIFTGRRLSGTEA 201
Cdd:PLN02157 130 GTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPG-RLGEYLGLTGLKLSGAEM 208
                        170
                 ....*....|....
gi 312176384 202 HVLGLVNHAVAQNE 215
Cdd:PLN02157 209 LACGLATHYIRSEE 222
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
39-211 1.68e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 54.58  E-value: 1.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADL--------------------KE 98
Cdd:PRK12478  12 AGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLR-GAGRAFSGGYDFgggfqhwgeammtdgrwdpgKD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  99 REQMSEAEVGVfVQRLRGlmndIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGlieTTRGLLPGAGGTQRLP 178
Cdd:PRK12478  91 FAMVTARETGP-TQKFMA----IWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIG---TPYSRMWGAYLTGMWL 162
                        170       180       190
                 ....*....|....*....|....*....|...
gi 312176384 179 RCLGVALAKELIFTGRRLSGTEAHVLGLVNHAV 211
Cdd:PRK12478 163 YRLSLAKVKWHSLTGRPLTGVQAAEAELINEAV 195
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
54-229 5.30e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 49.59  E-value: 5.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  54 NALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVfVQRLRGLMNDIAAFPAPTIAAMD 133
Cdd:PRK06213  24 NALSPAMIDALNAALDQAEDDRAVVVI---TGQPGIFSGGFDLKVMTSGAQAAIAL-LTAGSTLARRLLSHPKPVIVACT 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 134 GFALGGGLELALACDLRVAASSAV-MGLIETTRGL-LPGAG---GTQRLPRclgVALAKELIfTGRRLSGTEAHVLGLVN 208
Cdd:PRK06213 100 GHAIAKGAFLLLSADYRIGVHGPFkIGLNEVAIGMtMPHAAielARDRLTP---SAFQRAVI-NAEMFDPEEAVAAGFLD 175
                        170       180
                 ....*....|....*....|.
gi 312176384 209 HAVAQNEEGDAAYQRARALAQ 229
Cdd:PRK06213 176 EVVPPEQLLARAQAAARELAG 196
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
56-249 2.45e-05

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 44.70  E-value: 2.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384  56 LGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK--EREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMD 133
Cdd:PLN02267  23 LNPTLIDSIRSALRQVKSQATPGSVLITTAEGKFFSNGFDLAwaQAAGSAPSRLHLMVAKLRPLVADLISLPMPTIAAVT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312176384 134 GFALGGGLELALACDLRvaassavmgLIETTRGLLPGAGGTQRLP---------RC-LGVALA-KELIFTGRRLSGTEAH 202
Cdd:PLN02267 103 GHASAAGFILALSHDYV---------LMRKDRGVLYMSEVDIGLPlpdyfmallRAkIGSPAArRDVLLRAAKLTAEEAV 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 312176384 203 VLGLVnhavaqneegDAAYQRARALAQEilpqapiAVRLGKVAIDRG 249
Cdd:PLN02267 174 EMGIV----------DSAHDSAEETVEA-------AVRLGEELAARK 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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