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Conserved domains on  [gi|314122246|ref|NP_001186637|]
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putative tyrosine carboxypeptidase MATCAP2 isoform 5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF1704 super family cl06858
Domain of unknown function (DUF1704); This family contains many hypothetical proteins.
83-404 5.11e-15

Domain of unknown function (DUF1704); This family contains many hypothetical proteins.


The actual alignment was detected with superfamily member COG3930:

Pssm-ID: 471526  Cd Length: 391  Bit Score: 76.04  E-value: 5.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  83 KKFCILTAIKPTNLEKEKLRFFKSDYTYNPQFEYANPAL-PSVL------AKHSHASD---RFLKQSI------------ 140
Cdd:COG3930   30 KPIRILDAINPINIEQEKERFFASKFRELPEFRYRPLPFdPEALkrelysLRLEIIEDpplGKLLRRKideysrviqmle 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 141 -----NIMELTLQKYGSYEK-----------FEQATGGSLLSKTRIWSH-VRKYMmkEGCL------GEIVVHLTEDLLS 197
Cdd:COG3930  110 argtpDFYYNSLRLYGSPSDklidnarfildLADEELLEEPEEKTLSAEeAAARL--QERLdryfpgFPVRVEVSDDIVA 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 198 RASmtVVNGcpTLTINvSTAR--EHWLEGMLRHEIGTHYFRGINNLQQPwnswtgrkkheLK------PNN-PTEEGLAs 268
Cdd:COG3930  188 DAM--VGGD--RLKIR-KNARfsERDLEALEHHEIGVHVLTTLNGRAQP-----------LKilskglPGYtETQEGLA- 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 269 ihsVL-----FRKDPFlwRAALLYYTVYqASQM-----SFCELFkdigRFVK-----DPNTRWDYCVRAKRGwtdtsqpG 333
Cdd:COG3930  251 ---VLseylsGGLTPA--RLRRLALRVI-AVDMaedgaDFLDTF----RLLReqyglSREDAFTITLRVFRG-------G 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 314122246 334 CFSKDQVYLDGILQI---LRYRDTIDFhLLTalGKVSYEDVDRLKGLA----VTENMRVPHFLQDHGRYMEHLEKIME 404
Cdd:COG3930  314 GFTKDALYLRGLVEVynfLRSGGDLPL-LFV--GKVALEDLPVLQELVdrglLRPPKYLPPWLRDLNSNNPRLDRIRA 388
 
Name Accession Description Interval E-value
COG3930 COG3930
Uncharacterized conserved protein, DUF1704 domain [Function unknown];
83-404 5.11e-15

Uncharacterized conserved protein, DUF1704 domain [Function unknown];


Pssm-ID: 443131  Cd Length: 391  Bit Score: 76.04  E-value: 5.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  83 KKFCILTAIKPTNLEKEKLRFFKSDYTYNPQFEYANPAL-PSVL------AKHSHASD---RFLKQSI------------ 140
Cdd:COG3930   30 KPIRILDAINPINIEQEKERFFASKFRELPEFRYRPLPFdPEALkrelysLRLEIIEDpplGKLLRRKideysrviqmle 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 141 -----NIMELTLQKYGSYEK-----------FEQATGGSLLSKTRIWSH-VRKYMmkEGCL------GEIVVHLTEDLLS 197
Cdd:COG3930  110 argtpDFYYNSLRLYGSPSDklidnarfildLADEELLEEPEEKTLSAEeAAARL--QERLdryfpgFPVRVEVSDDIVA 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 198 RASmtVVNGcpTLTINvSTAR--EHWLEGMLRHEIGTHYFRGINNLQQPwnswtgrkkheLK------PNN-PTEEGLAs 268
Cdd:COG3930  188 DAM--VGGD--RLKIR-KNARfsERDLEALEHHEIGVHVLTTLNGRAQP-----------LKilskglPGYtETQEGLA- 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 269 ihsVL-----FRKDPFlwRAALLYYTVYqASQM-----SFCELFkdigRFVK-----DPNTRWDYCVRAKRGwtdtsqpG 333
Cdd:COG3930  251 ---VLseylsGGLTPA--RLRRLALRVI-AVDMaedgaDFLDTF----RLLReqyglSREDAFTITLRVFRG-------G 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 314122246 334 CFSKDQVYLDGILQI---LRYRDTIDFhLLTalGKVSYEDVDRLKGLA----VTENMRVPHFLQDHGRYMEHLEKIME 404
Cdd:COG3930  314 GFTKDALYLRGLVEVynfLRSGGDLPL-LFV--GKVALEDLPVLQELVdrglLRPPKYLPPWLRDLNSNNPRLDRIRA 388
DUF1704 pfam08014
Domain of unknown function (DUF1704); This family contains many hypothetical proteins.
102-404 1.61e-09

Domain of unknown function (DUF1704); This family contains many hypothetical proteins.


Pssm-ID: 429786  Cd Length: 365  Bit Score: 59.17  E-value: 1.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  102 RFFKSDYTYNPQFEYA----NP-----ALPSVLAKH--SHASDRFLKQSIN----------------IMELTLQKYGSYE 154
Cdd:pfam08014   2 RFFASKFRELPQVDYRplgfDPaatkrELYEIRRDIieDPPLGQLLRRKCDeyalvirmleargtpeFLYNSRRLYGSPS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  155 KFEQATGGSLLSKTRIWSH----------------------VRKYMmkEGCL------GEIVVHLTEDLLSRASMtvvnG 206
Cdd:pfam08014  82 DPFHGGGPTLLELARFLLHilsnldpeplneeeekrisaeeAAEIL--QERLdayfggFAVRVELSDDLVADAAA----G 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  207 CPTLTINVSTAREHW-LEGMLRHEIGTHYFRGINNLQQPWNSWtgrkkheLKPNNP----TEEGLASIHSVL-FRKDPFl 280
Cdd:pfam08014 156 ADRIKLRSNAMFSDRdLDALEHHEGGVHVLTTLNGRAQPYLTF-------LSKGLPgntaTQEGLAVLAEYLtGSLTPK- 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  281 wRAALLYYTVyQASQM-----SFCELFKDIGRFVKDPNTRWDYCVRAKRGWTDTSqpGCFSKDQVYLDGILQIL-RYRDT 354
Cdd:pfam08014 228 -RLRRLADRV-VAVDMaedgaDFLDVFRYLLERGLSEEDAFTITQRVFRGGTPEG--GGFTKDALYLRGLVEVYnFIRSA 303
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 314122246  355 IDFHLLTAL-----GKVSYEDVDRLKGLAVTENMRVPHFLQDHGRYMEHLEKIME 404
Cdd:pfam08014 304 VARGRLDLLpllfvGKLALDDIPLLAELVERGLLTPPRYLPPWFRDLRGLNAWLA 358
 
Name Accession Description Interval E-value
COG3930 COG3930
Uncharacterized conserved protein, DUF1704 domain [Function unknown];
83-404 5.11e-15

Uncharacterized conserved protein, DUF1704 domain [Function unknown];


Pssm-ID: 443131  Cd Length: 391  Bit Score: 76.04  E-value: 5.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  83 KKFCILTAIKPTNLEKEKLRFFKSDYTYNPQFEYANPAL-PSVL------AKHSHASD---RFLKQSI------------ 140
Cdd:COG3930   30 KPIRILDAINPINIEQEKERFFASKFRELPEFRYRPLPFdPEALkrelysLRLEIIEDpplGKLLRRKideysrviqmle 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 141 -----NIMELTLQKYGSYEK-----------FEQATGGSLLSKTRIWSH-VRKYMmkEGCL------GEIVVHLTEDLLS 197
Cdd:COG3930  110 argtpDFYYNSLRLYGSPSDklidnarfildLADEELLEEPEEKTLSAEeAAARL--QERLdryfpgFPVRVEVSDDIVA 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 198 RASmtVVNGcpTLTINvSTAR--EHWLEGMLRHEIGTHYFRGINNLQQPwnswtgrkkheLK------PNN-PTEEGLAs 268
Cdd:COG3930  188 DAM--VGGD--RLKIR-KNARfsERDLEALEHHEIGVHVLTTLNGRAQP-----------LKilskglPGYtETQEGLA- 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246 269 ihsVL-----FRKDPFlwRAALLYYTVYqASQM-----SFCELFkdigRFVK-----DPNTRWDYCVRAKRGwtdtsqpG 333
Cdd:COG3930  251 ---VLseylsGGLTPA--RLRRLALRVI-AVDMaedgaDFLDTF----RLLReqyglSREDAFTITLRVFRG-------G 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 314122246 334 CFSKDQVYLDGILQI---LRYRDTIDFhLLTalGKVSYEDVDRLKGLA----VTENMRVPHFLQDHGRYMEHLEKIME 404
Cdd:COG3930  314 GFTKDALYLRGLVEVynfLRSGGDLPL-LFV--GKVALEDLPVLQELVdrglLRPPKYLPPWLRDLNSNNPRLDRIRA 388
DUF1704 pfam08014
Domain of unknown function (DUF1704); This family contains many hypothetical proteins.
102-404 1.61e-09

Domain of unknown function (DUF1704); This family contains many hypothetical proteins.


Pssm-ID: 429786  Cd Length: 365  Bit Score: 59.17  E-value: 1.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  102 RFFKSDYTYNPQFEYA----NP-----ALPSVLAKH--SHASDRFLKQSIN----------------IMELTLQKYGSYE 154
Cdd:pfam08014   2 RFFASKFRELPQVDYRplgfDPaatkrELYEIRRDIieDPPLGQLLRRKCDeyalvirmleargtpeFLYNSRRLYGSPS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  155 KFEQATGGSLLSKTRIWSH----------------------VRKYMmkEGCL------GEIVVHLTEDLLSRASMtvvnG 206
Cdd:pfam08014  82 DPFHGGGPTLLELARFLLHilsnldpeplneeeekrisaeeAAEIL--QERLdayfggFAVRVELSDDLVADAAA----G 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  207 CPTLTINVSTAREHW-LEGMLRHEIGTHYFRGINNLQQPWNSWtgrkkheLKPNNP----TEEGLASIHSVL-FRKDPFl 280
Cdd:pfam08014 156 ADRIKLRSNAMFSDRdLDALEHHEGGVHVLTTLNGRAQPYLTF-------LSKGLPgntaTQEGLAVLAEYLtGSLTPK- 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 314122246  281 wRAALLYYTVyQASQM-----SFCELFKDIGRFVKDPNTRWDYCVRAKRGWTDTSqpGCFSKDQVYLDGILQIL-RYRDT 354
Cdd:pfam08014 228 -RLRRLADRV-VAVDMaedgaDFLDVFRYLLERGLSEEDAFTITQRVFRGGTPEG--GGFTKDALYLRGLVEVYnFIRSA 303
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 314122246  355 IDFHLLTAL-----GKVSYEDVDRLKGLAVTENMRVPHFLQDHGRYMEHLEKIME 404
Cdd:pfam08014 304 VARGRLDLLpllfvGKLALDDIPLLAELVERGLLTPPRYLPPWFRDLRGLNAWLA 358
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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