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Conserved domains on  [gi|315434220|ref|NP_001186781|]
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GTP:AMP phosphotransferase AK3, mitochondrial isoform b [Homo sapiens]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11995178)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
12-150 5.92e-73

Adenylate kinase;


:

Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 217.95  E-value: 5.92e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT----------------------------------------- 50
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTelgkeakeymdkgelvpdevvvglvkerleqndckngflld 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   51 GFPRTLPQAEALDR----AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP 126
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 315434220  127 ETVIKRLKAYEDQTKPVLEYYQKK 150
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
12-150 5.92e-73

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 217.95  E-value: 5.92e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT----------------------------------------- 50
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTelgkeakeymdkgelvpdevvvglvkerleqndckngflld 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   51 GFPRTLPQAEALDR----AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP 126
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 315434220  127 ETVIKRLKAYEDQTKPVLEYYQKK 150
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 9-159 2.67e-72

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 217.30  E-value: 2.67e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:COG0563    2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTelgkkakeymdagelvpdeiviglvkerlaqpdcangf 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDRA-----YQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQRE 122
Cdd:COG0563   82 ildGFPRTVAQAEALDELlaelgIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 315434220 123 DDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT 159
Cdd:COG0563  162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 9-173 1.46e-71

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 215.18  E-value: 1.46e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220    9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTplgkkakeymekgelvpdeivnqlvkerltqnddneng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   51 ----GFPRTLPQAEALDR--AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDD 124
Cdd:TIGR01351  81 fildGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 315434220  125 KPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT-ETNKIWPYVYAFLQ 173
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
adk PRK00279
adenylate kinase; Reviewed
 8-159 3.51e-70

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 211.93  E-value: 3.51e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT------------------------------------- 50
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTelgkeaksymdagelvpdeiviglvkerlaqpdckng 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ----GFPRTLPQAEALDRAY-----QIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQR 121
Cdd:PRK00279  81 flldGFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 315434220 122 EDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT 159
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGT 198
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 9-161 7.46e-62

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 190.14  E-value: 7.46e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTelgkkakeyidsgklvpdeivikllkerlkkpdckkgf 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDRAYQ----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIefnppktvGIDDLTGEPLIQRED 123
Cdd:cd01428   81 ildGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 315434220 124 DKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET 161
Cdd:cd01428  153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
12-150 5.92e-73

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 217.95  E-value: 5.92e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT----------------------------------------- 50
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTelgkeakeymdkgelvpdevvvglvkerleqndckngflld 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   51 GFPRTLPQAEALDR----AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP 126
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 315434220  127 ETVIKRLKAYEDQTKPVLEYYQKK 150
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 9-159 2.67e-72

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 217.30  E-value: 2.67e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:COG0563    2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTelgkkakeymdagelvpdeiviglvkerlaqpdcangf 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDRA-----YQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQRE 122
Cdd:COG0563   82 ildGFPRTVAQAEALDELlaelgIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 315434220 123 DDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT 159
Cdd:COG0563  162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 9-173 1.46e-71

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 215.18  E-value: 1.46e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220    9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTplgkkakeymekgelvpdeivnqlvkerltqnddneng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   51 ----GFPRTLPQAEALDR--AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDD 124
Cdd:TIGR01351  81 fildGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 315434220  125 KPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT-ETNKIWPYVYAFLQ 173
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
adk PRK00279
adenylate kinase; Reviewed
 8-159 3.51e-70

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 211.93  E-value: 3.51e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT------------------------------------- 50
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTelgkeaksymdagelvpdeiviglvkerlaqpdckng 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ----GFPRTLPQAEALDRAY-----QIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQR 121
Cdd:PRK00279  81 flldGFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 315434220 122 EDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT 159
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGT 198
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 9-161 7.46e-62

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 190.14  E-value: 7.46e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTelgkkakeyidsgklvpdeivikllkerlkkpdckkgf 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDRAYQ----IDTVINLNVPFEVIKQRLTARWIHPASGRVYNIefnppktvGIDDLTGEPLIQRED 123
Cdd:cd01428   81 ildGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 315434220 124 DKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET 161
Cdd:cd01428  153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
PLN02674 PLN02674
adenylate kinase
 9-153 1.84e-48

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 157.74  E-value: 1.84e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLR------------------------DNMLRGT-------------- 50
Cdd:PLN02674  33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRaavaaktplgikakeamdkgelvsDDLVVGIideamkkpscqkgf 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQRE 122
Cdd:PLN02674 113 ildGFPRTVVQAQKLDemlakQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192

                        170       180       190
                 ....*....|....*....|....*....|.
gi 315434220 123 DDKPETVIKRLKAYEDQTKPVLEYYQKKGVL 153
Cdd:PLN02674 193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVV 223
PRK14530 PRK14530
adenylate kinase; Provisional
 9-165 1.17e-40

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 136.84  E-value: 1.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDN------------------MLRGT-------------------- 50
Cdd:PRK14530   5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANkqmdisdmdteydtpgeyMDAGElvpdavvneiveealsdadg 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ----GFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP 126
Cdd:PRK14530  85 fvldGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQRDDDTE 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 315434220 127 ETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET-NKIW 165
Cdd:PRK14530 165 ETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVW 204
PRK14526 PRK14526
adenylate kinase; Provisional
 8-149 1.84e-29

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 108.01  E-value: 1.84e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT------------------------------------- 50
Cdd:PRK14526   1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTplgkeikqivengqlvpdsitikivedkintiknndn 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ----GFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP 126
Cdd:PRK14526  81 fildGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDDKE 160

                        170       180
                 ....*....|....*....|...
gi 315434220 127 ETVIKRLKAYEDQTKPVLEYYQK 149
Cdd:PRK14526 161 ESLKTRLQEYKLQTKPLIEFYSK 183
PLN02459 PLN02459
probable adenylate kinase
 11-156 7.53e-26

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 99.54  E-value: 7.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT---------------------------------------- 50
Cdd:PLN02459  33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGplgaqlkeivnqgklvpdeiifsllskrleageeegesgf 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNI------EFNPPKTVGIDDLTGEP---- 117
Cdd:PLN02459 113 ildGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVadidlkGEDGRPGIVMPPLLPPPecas 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 315434220 118 -LIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETF 156
Cdd:PLN02459 193 kLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
adk PRK02496
adenylate kinase; Provisional
 9-161 1.39e-21

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 86.73  E-value: 1.39e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:PRK02496   3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTplgikaqgymdkgelvpdqlvldlvqerlqqpdaangw 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARwihpasgrvyniefnppktvgiddltgepliQRE 122
Cdd:PRK02496  83 ildGFPRKVTQAAFLDEllqeiGQSGERVVNLDVPDDVVVERLLAR-------------------------------GRK 131

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 315434220 123 DDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET 161
Cdd:PRK02496 132 DDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQS 170
PRK14527 PRK14527
adenylate kinase; Provisional
 9-161 2.67e-21

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 86.00  E-value: 2.67e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVI-MGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT------------------------------------- 50
Cdd:PRK14527   7 KVVIfLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTelgqrakpimeagdlvpdelilalirdelagmepvrv 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARwihpasGRvyniefnppktvgiddltgepLIQRE 122
Cdd:PRK14527  87 ifdGFPRTLAQAEALDRlleelGARLLAVVLLEVPDEELIRRIVER------AR---------------------QEGRS 139

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 315434220 123 DDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET 161
Cdd:PRK14527 140 DDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGT 178
PRK14532 PRK14532
adenylate kinase; Provisional
 11-158 5.58e-21

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 85.26  E-value: 5.58e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT---------------------------------------- 50
Cdd:PRK14532   4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSelgqrvkgimdrgelvsdeivialieerlpeaeaaggaif 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 -GFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTARWIHPAsgrvyniefnppktvgiddltgepliqREDD 124
Cdd:PRK14532  84 dGFPRTVAQAEALDkmlasRGQKIDVVIRLKVDDEALIERIVKRFEEQG---------------------------RPDD 136

                        170       180       190
                 ....*....|....*....|....*....|....
gi 315434220 125 KPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSG 158
Cdd:PRK14532 137 NPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDG 170
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 6-152 1.89e-20

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 84.85  E-value: 1.89e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   6 RLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT----------------------------------- 50
Cdd:PTZ00088   5 GPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTtigkeiqkvvtsgnlvpdnlviaivkdeiakvtdd 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 --------GFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIE-----------FNPPKtvGID 111
Cdd:PTZ00088  85 cfkgfildGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIAhirsdpydmppILPPA--DCE 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 315434220 112 DLTGEP-LIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGV 152
Cdd:PTZ00088 163 GCKGNPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
PRK14531 PRK14531
adenylate kinase; Provisional
 9-155 3.54e-20

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 82.94  E-value: 3.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDN--------------MLRGT------------------------ 50
Cdd:PRK14531   4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEvaagsalgqeaeavMNRGElvsdalvlaivesqlkalnsggwl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 --GFPRTLPQAEALDRAYQ-----IDTVINLNVPFEVIKQRLTARwihpasGRvyniefnppktvgiddltgepliqreD 123
Cdd:PRK14531  84 ldGFPRTVAQAEALEPLLEelkqpIEAVVLLELDDAVLIERLLAR------GR--------------------------A 131

                        170       180       190
                 ....*....|....*....|....*....|...
gi 315434220 124 DKPETVIK-RLKAYEDQTKPVLEYYQKKGVLET 155
Cdd:PRK14531 132 DDNEAVIRnRLEVYREKTAPLIDHYRQRGLLQS 164
PLN02842 PLN02842
nucleotide kinase
 11-147 2.54e-19

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 84.53  E-value: 2.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT---------------------------------------- 50
Cdd:PLN02842   1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTdigkrakefmnsgrlvpdeiviamvtgrlsredakekgwl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 --GFPRTLPQAEALDR-AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDdltgEPLIQREDDKPE 127
Cdd:PLN02842  81 ldGYPRSFAQAQSLEKlKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEIK----ARLITRPDDTEE 156

                        170       180
                 ....*....|....*....|
gi 315434220 128 TVIKRLKAYEDQTKPVLEYY 147
Cdd:PLN02842 157 KVKARLQIYKKNAEAILSTY 176
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 12-159 7.82e-19

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 79.34  E-value: 7.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLR--------------DNMLRG---------------------------- 49
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRaeikregsengsliESYIKEgkivpsevtvellkkaiqedgsskkfli 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   50 TGFPRTLPQAEA----LDRAYQIDTVINLNVPFEVIKQRLTARwiHPASGRVyniefnppktvgiddltgepliqreDDK 125
Cdd:TIGR01359  84 DGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKR--GQTSGRV-------------------------DDN 136

                         170       180       190
                  ....*....|....*....|....*....|....
gi 315434220  126 PETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGT 159
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFENKGKVKEINAE 170
PRK13808 PRK13808
adenylate kinase; Provisional
 8-158 3.41e-18

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 80.32  E-value: 3.41e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT------------------------------------- 50
Cdd:PRK13808   1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTpvglkakdimasgglvpdevvvgiisdrieqpdaang 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ----GFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARwihPASGRVyniefnppktvgiddlTGEPLiqR 121
Cdd:PRK13808  81 fildGFPRTVPQAEALDAllkdkQLKLDAVVELRVNEGALLARVETR---VAEMRA----------------RGEEV--R 139

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 315434220 122 EDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSG 158
Cdd:PRK13808 140 ADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDG 176
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 88-123 1.85e-17

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 71.72  E-value: 1.85e-17
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 315434220   88 RWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQRED 123
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 12-155 7.89e-17

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 74.47  E-value: 7.89e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTGFPRTLPQAEALDRAYQIDTVINLnVPFEVIKQRLTARWI- 90
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDL-LKDAMVAALGTSKGFl 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   91 ---HP---ASGRVYNIEFNPPKTVGIDDLTGEPLIQR----------EDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLE 154
Cdd:TIGR01360  87 idgYPrevKQGEEFERRIGPPTLVLYFDCSEDTMVKRllkraetsgrVDDNEKTIKKRLETYYKATEPVIAYYETKGKLR 166


                  .
gi 315434220  155 T 155
Cdd:TIGR01360 167 K 167
PRK14528 PRK14528
adenylate kinase; Provisional
 9-161 2.70e-16

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 72.74  E-value: 2.70e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   9 RAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT-------------------------------------- 50
Cdd:PRK14528   3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTamgieakrymdagdlvpdsvvigiikdrireadckngf 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 ---GFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARWIHPAsgrvyniefnppktvgiddltgepliqRE 122
Cdd:PRK14528  83 lldGFPRTVEQADALDAllkneGKSIDKAINLEVPDGELLKRLLGRAEIEG---------------------------RA 135

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 315434220 123 DDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTET 161
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGS 174
AAA_17 pfam13207
AAA domain;
13-101 1.36e-13

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 64.57  E-value: 1.36e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   13 MGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT---------------------------------------GFP 53
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERGlvedrdemrklplepqkelqklaaeriaeeageggvivdGHP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 315434220   54 RTLPQAEALD-------RAYQIDTVINLNVPFEVIKQRLTARwihPASGRVY-NIE 101
Cdd:pfam13207  81 RIKTPAGYLPglpvevlRELKPDAIILLEADPEEILERRLKD---RTRGRDDdSEE 133
PLN02200 PLN02200
adenylate kinase family protein
 12-175 6.07e-11

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 59.14  E-value: 6.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT----------------------------------------G 51
Cdd:PLN02200  48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSehgamilntikegkivpsevtvkliqkemessdnnkflidG 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  52 FPRTLPQAEALDR--AYQIDTVINLNVPFEVIKQRLTARwihpASGRVyniefnppktvgiddltgepliqreDDKPETV 129
Cdd:PLN02200 128 FPRTEENRIAFERiiGAEPNVVLFFDCPEEEMVKRVLNR----NQGRV-------------------------DDNIDTI 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 315434220 130 IKRLKAYEDQTKPVLEYYQKKGVLETFSGTET-----NKIWPYVYAFLQTK 175
Cdd:PLN02200 179 KKRLKVFNALNLPVIDYYSKKGKLYTINAVGTvdeifEQVRPIFAACEAMK 229
PRK14529 PRK14529
adenylate kinase; Provisional
 11-150 1.80e-10

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 57.81  E-value: 1.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT---------------------------------------- 50
Cdd:PRK14529   4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTelgkkakeyidrgdlvpdditipmiletlkqdgkngwlld 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  51 GFPRTLPQAEALDRAYQ-----IDTVINLNVPFEVIKQRLTARWI------HPAsgrvyNIEFNPPKTVG-IDDLTGEPL 118
Cdd:PRK14529  84 GFPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGRRLckndnnHPN-----NIFIDAIKPDGdVCRVCGGEL 158

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 315434220 119 IQREDDKPETVI-KRLKAYEDQTKPVLE--YYQKK 150
Cdd:PRK14529 159 STRADDQDEEAInKRHDIYYDTETGTLAaaYFFKD 193
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 11-91 2.49e-05

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 42.24  E-value: 2.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  11 VIMGAPGSGKGTVSSRITTHFELKHLsSGDLLR-----DNMLRGT------------------------GFPRTLPQAEA 61
Cdd:cd02021    3 VVMGVSGSGKSTVGKALAERLGAPFI-DGDDLHppaniAKMAAGIplndedrwpwlqaltdallaklasAGEGVVVACSA 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 315434220  62 LDRAYQI----------DTVINLNVPFEVIKQRLTARWIH 91
Cdd:cd02021   82 LKRIYRDilrggaanprVRFVHLDGPREVLAERLAARKGH 121
PRK04182 PRK04182
cytidylate kinase; Provisional
 8-44 3.96e-05

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 42.10  E-value: 3.96e-05
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 315434220   8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRD 44
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 12-41 1.77e-04

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 39.78  E-value: 1.77e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 315434220  12 IMGAPGSGKGTVSSRITTHFELKHLSSGDL 41
Cdd:cd02020    4 IDGPAGSGKSTVAKLLAKKLGLPYLDTGGI 33
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
11-88 7.64e-04

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 38.36  E-value: 7.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220  11 VIMGAPGSGKGTVSSRITTHFELKHLSSgDLLRdNMLRGTGFPRTLPQAEALDRAYQ-----------------ID---- 69
Cdd:COG0645    3 LVCGLPGSGKSTLARALAERLGAVRLRS-DVVR-KRLFGAGLAPLERSPEATARTYArllalarellaagrsviLDatfl 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 315434220  70 -------------------TVINLNVPFEVIKQRLTAR 88
Cdd:COG0645   81 rraqreafralaeeagapfVLIWLDAPEEVLRERLEAR 118
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 11-89 7.86e-04

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 38.06  E-value: 7.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315434220   11 VIM-GAPGSGKGTVSSRITTHFELKHLSSGDLLRdnMLRGTGFPRTLPQAEALDRAYQIdtvinlnvPFEVIKQRLTARW 89
Cdd:pfam13671   2 ILLvGLPGSGKSTLARRLLEELGAVRLSSDDERK--RLFGEGRPSISYYTDATDRTYER--------LHELARIALRAGR 71
AAA_18 pfam13238
AAA domain;
11-74 8.73e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 34.71  E-value: 8.73e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 315434220   11 VIMGAPGSGKGTVSSRITTHFELkHLSSGDLLRDNMLRGTGFPRTlPQAEALDRAYQIDTVINL 74
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGF-GDNVRDLALENGLVLGDDPET-RESKRLDEDKLDRLLDLL 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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