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Conserved domains on  [gi|324120978|ref|NP_001191226|]
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mucin-1 isoform 21 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEA super family cl02507
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 64-103 5.09e-13

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


The actual alignment was detected with superfamily member smart00200:

Pssm-ID: 470595  Cd Length: 121  Bit Score: 62.43  E-value: 5.09e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 324120978    64 STGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEM 103
Cdd:smart00200   4 SFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKL 43
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 64-103 5.09e-13

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 62.43  E-value: 5.09e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 324120978    64 STGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEM 103
Cdd:smart00200   4 SFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKL 43
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 69-103 1.21e-06

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 44.92  E-value: 1.21e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 324120978   69 FFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEM 103
Cdd:pfam01390   2 YYTGSFKITNLQYTPDLGNPSSQEFKSLSRRIESL 36
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 64-103 5.09e-13

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 62.43  E-value: 5.09e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 324120978    64 STGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEM 103
Cdd:smart00200   4 SFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKL 43
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 69-103 1.21e-06

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 44.92  E-value: 1.21e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 324120978   69 FFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEM 103
Cdd:pfam01390   2 YYTGSFKITNLQYTPDLGNPSSQEFKSLSRRIESL 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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