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Conserved domains on  [gi|1477471259|ref|NP_001229601|]
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tetratricopeptide repeat protein 34 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1000094)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 690-909 8.57e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 8.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  690 ASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGP--GTVVPELrslk 767
Cdd:COG2956      7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPdrAEALLEL---- 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  768 peAQALITQGLYSHCRALLSQLPDTGAP------------LEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSY 835
Cdd:COG2956     83 --AQDYLKAGLLDRAEELLEKLLELDPDdaealrllaeiyEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY 160

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1477471259  836 EEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQE 909
Cdd:COG2956    161 DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 809-1031 1.93e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.74  E-value: 1.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  809 EALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLS 888
Cdd:COG2956     32 EEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  889 CLLHLLEASERQSLAQAAAQEAGTLLDAgQPRQALGYCSLSVLASG-------------------SSACHLRLRATCLAE 949
Cdd:COG2956    112 ALRLLAEIYEQEGDWEKAIEVLERLLKL-GPENAHAYCELAELYLEqgdydeaiealekalkldpDCARALLLLAELYLE 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  950 LQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPS----LAQNSLCRQPGRAPTA 1025
Cdd:COG2956    191 QGDYEEAIAALERALEQD------PDYLPALPRLAELYEKLGDPEEALELLRKALELDPSddllLALADLLERKEGLEAA 264


                   ....*.
gi 1477471259 1026 RMFLLR 1031
Cdd:COG2956    265 LALLER 270
COG3903 super family cl43979
Predicted ATPase [General function prediction only];
131-533 6.76e-04

Predicted ATPase [General function prediction only];


The actual alignment was detected with superfamily member COG3903:

Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.85  E-value: 6.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  131 SHAQQVLELRLTRALAWVLSGVQAADGVAAYLQAFASSADRTVAfirthqrphlPALLSALQDYLSGHPEAGHSAGQQET 210
Cdd:COG3903    537 AHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAA----------ALAAAAALAAAAAAARAAAAAAAAAA 606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  211 GGQRLLAALDPRGTRSDTLSPEALLHSGRFEDCLAACSRALEAHPTGSEPQGERRAALLVTRAASAFFLDGRAQDVFWNL 290
Cdd:COG3903    607 AAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAA 686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  291 QEAFRESPSGARRQFQAVFSVQDQERVRAQAQEAADVGFARFQEAVRNHPELREDAGRELLAPVTRALRVLLRLAPAGAR 370
Cdd:COG3903    687 LAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAA 766

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  371 PALGARLAECLLLAGDAAGARAMCERLLRPARPEDPAGDRAGDRAPLLALRGFCALHAGDSRRAMEDFQTVVEQGAPHPG 450
Cdd:COG3903    767 AAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAA 846

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  451 GCVRALCGRGLLRVLAGSAFLGTLDYVTACRLRPEEALLAAKAYVPWNQRGLLLVVLREEARGMLQRSPRAGPSRAQGRR 530
Cdd:COG3903    847 AAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAA 926


                   ...
gi 1477471259  531 EAA 533
Cdd:COG3903    927 AAA 929
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 690-909 8.57e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 8.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  690 ASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGP--GTVVPELrslk 767
Cdd:COG2956      7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPdrAEALLEL---- 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  768 peAQALITQGLYSHCRALLSQLPDTGAP------------LEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSY 835
Cdd:COG2956     83 --AQDYLKAGLLDRAEELLEKLLELDPDdaealrllaeiyEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY 160

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1477471259  836 EEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQE 909
Cdd:COG2956    161 DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 557-925 7.44e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 7.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  557 ELDSEDEASRLLA--ADALYRLGRLEETHKALLVALSRRPQAAPVLARLALLQLRRGFFYDANQLVKKLVQsgdtacLQP 634
Cdd:TIGR02917  117 TLLDDEGAAELLAlrGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLT------ADP 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  635 TldvfcHEDRQLLQGHcharalaILRARPGGAdgrvhtkEAIAYLSLAIfAAGSQASESLLARARCYGFLGQKKTAMFDF 714
Cdd:TIGR02917  191 G-----NVDALLLKGD-------LLLSLGNIE-------LALAAYRKAI-ALRPNNIAVLLALATILIEAGEFEEAEKHA 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  715 NTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGP---------GTVVPELRSLKpeaQAlitqglYSHCRAL 785
Cdd:TIGR02917  251 DALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPeylpalllaGASEYQLGNLE---QA------YQYLNQI 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  786 LSQLPD--------TGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARA 857
Cdd:TIGR02917  322 LKYAPNshqarrllASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAART 401

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1477471259  858 RLGLLQLKKGDVPGAARDLQSLAEVDA----PDLSCLLHLLEASERQSlAQAAAQEagtlLDAGQPRQALGY 925
Cdd:TIGR02917  402 QLGISKLSQGDPSEAIADLETAAQLDPelgrADLLLILSYLRSGQFDK-ALAAAKK----LEKKQPDNASLH 468
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 809-1031 1.93e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.74  E-value: 1.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  809 EALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLS 888
Cdd:COG2956     32 EEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  889 CLLHLLEASERQSLAQAAAQEAGTLLDAgQPRQALGYCSLSVLASG-------------------SSACHLRLRATCLAE 949
Cdd:COG2956    112 ALRLLAEIYEQEGDWEKAIEVLERLLKL-GPENAHAYCELAELYLEqgdydeaiealekalkldpDCARALLLLAELYLE 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  950 LQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPS----LAQNSLCRQPGRAPTA 1025
Cdd:COG2956    191 QGDYEEAIAALERALEQD------PDYLPALPRLAELYEKLGDPEEALELLRKALELDPSddllLALADLLERKEGLEAA 264


                   ....*.
gi 1477471259 1026 RMFLLR 1031
Cdd:COG2956    265 LALLER 270
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 803-1069 4.24e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 4.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  803 GLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEV 882
Cdd:TIGR02917    6 ALLCIALALSACGDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  883 DAPDLSCLLHLLEASERQSLAQAAAQEAG--TLLDAGQPRQALGYCSLSVLASG-----------------SSACHLRLR 943
Cdd:TIGR02917   86 GYPKNQVLPLLARAYLLQGKFQQVLDELPgkTLLDDEGAAELLALRGLAYLGLGqlelaqksyeqalaidpRSLYAKLGL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  944 ATCLAELQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPslaqnslcrqpgRAP 1023
Cdd:TIGR02917  166 AQLALAENRFDEARALIDEVLTAD------PGNVDALLLKGDLLLSLGNIELALAAYRKAIALRP------------NNI 227

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1477471259 1024 TARMFLlrGQCCLEEQRHAEAWTAVESGLLVDPDHRGLKRLKARIR 1069
Cdd:TIGR02917  228 AVLLAL--ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD 271
COG3903 COG3903
Predicted ATPase [General function prediction only];
131-533 6.76e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.85  E-value: 6.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  131 SHAQQVLELRLTRALAWVLSGVQAADGVAAYLQAFASSADRTVAfirthqrphlPALLSALQDYLSGHPEAGHSAGQQET 210
Cdd:COG3903    537 AHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAA----------ALAAAAALAAAAAAARAAAAAAAAAA 606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  211 GGQRLLAALDPRGTRSDTLSPEALLHSGRFEDCLAACSRALEAHPTGSEPQGERRAALLVTRAASAFFLDGRAQDVFWNL 290
Cdd:COG3903    607 AAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAA 686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  291 QEAFRESPSGARRQFQAVFSVQDQERVRAQAQEAADVGFARFQEAVRNHPELREDAGRELLAPVTRALRVLLRLAPAGAR 370
Cdd:COG3903    687 LAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAA 766

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  371 PALGARLAECLLLAGDAAGARAMCERLLRPARPEDPAGDRAGDRAPLLALRGFCALHAGDSRRAMEDFQTVVEQGAPHPG 450
Cdd:COG3903    767 AAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAA 846

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  451 GCVRALCGRGLLRVLAGSAFLGTLDYVTACRLRPEEALLAAKAYVPWNQRGLLLVVLREEARGMLQRSPRAGPSRAQGRR 530
Cdd:COG3903    847 AAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAA 926


                   ...
gi 1477471259  531 EAA 533
Cdd:COG3903    927 AAA 929
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 820-900 3.51e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 40.95  E-value: 3.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  820 HWHLLLADILMAQGSYEEAGTHLEKALHRAPTSeaARAR--LGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEAS 897
Cdd:PRK11788   181 HFYCELAQQALARGDLDAARALLKKALAADPQC--VRASilLGDLALAQGDYAAAIEALERVEEQDPEYLSEVLPKLMEC 258


                   ...
gi 1477471259  898 ERQ 900
Cdd:PRK11788   259 YQA 261
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 690-909 8.57e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 8.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  690 ASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGP--GTVVPELrslk 767
Cdd:COG2956      7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPdrAEALLEL---- 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  768 peAQALITQGLYSHCRALLSQLPDTGAP------------LEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSY 835
Cdd:COG2956     83 --AQDYLKAGLLDRAEELLEKLLELDPDdaealrllaeiyEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY 160

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1477471259  836 EEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQE 909
Cdd:COG2956    161 DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 557-925 7.44e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 7.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  557 ELDSEDEASRLLA--ADALYRLGRLEETHKALLVALSRRPQAAPVLARLALLQLRRGFFYDANQLVKKLVQsgdtacLQP 634
Cdd:TIGR02917  117 TLLDDEGAAELLAlrGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLT------ADP 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  635 TldvfcHEDRQLLQGHcharalaILRARPGGAdgrvhtkEAIAYLSLAIfAAGSQASESLLARARCYGFLGQKKTAMFDF 714
Cdd:TIGR02917  191 G-----NVDALLLKGD-------LLLSLGNIE-------LALAAYRKAI-ALRPNNIAVLLALATILIEAGEFEEAEKHA 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  715 NTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGP---------GTVVPELRSLKpeaQAlitqglYSHCRAL 785
Cdd:TIGR02917  251 DALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPeylpalllaGASEYQLGNLE---QA------YQYLNQI 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  786 LSQLPD--------TGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARA 857
Cdd:TIGR02917  322 LKYAPNshqarrllASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAART 401

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1477471259  858 RLGLLQLKKGDVPGAARDLQSLAEVDA----PDLSCLLHLLEASERQSlAQAAAQEagtlLDAGQPRQALGY 925
Cdd:TIGR02917  402 QLGISKLSQGDPSEAIADLETAAQLDPelgrADLLLILSYLRSGQFDK-ALAAAKK----LEKKQPDNASLH 468
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 674-914 3.59e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 3.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  674 EAIAYLSLAIfAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALK 753
Cdd:COG2956     60 RAIRIHQKLL-ERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  754 LGPGtvvpelrslkpEAQALITQGLYShcrallsqlpdtgapLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQG 833
Cdd:COG2956    139 LGPE-----------NAHAYCELAELY---------------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  834 SYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDaPDLSCLLHLLEASERQSLAQAAAQEAGTL 913
Cdd:COG2956    193 DYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELD-PSDDLLLALADLLERKEGLEAALALLERQ 271


                   .
gi 1477471259  914 L 914
Cdd:COG2956    272 L 272
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
692-923 1.44e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 1.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  692 ESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTvvpelrslkpeAQ 771
Cdd:COG0457      9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-----------AE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  772 ALITQGLyshcraLLSQLpdtgapledKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPT 851
Cdd:COG0457     78 ALNNLGL------ALQAL---------GRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPD 142

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1477471259  852 SEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQEAGTLLDAGQPRQAL 923
Cdd:COG0457    143 DADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAIL 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 809-1031 1.93e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.74  E-value: 1.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  809 EALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLS 888
Cdd:COG2956     32 EEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  889 CLLHLLEASERQSLAQAAAQEAGTLLDAgQPRQALGYCSLSVLASG-------------------SSACHLRLRATCLAE 949
Cdd:COG2956    112 ALRLLAEIYEQEGDWEKAIEVLERLLKL-GPENAHAYCELAELYLEqgdydeaiealekalkldpDCARALLLLAELYLE 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  950 LQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPS----LAQNSLCRQPGRAPTA 1025
Cdd:COG2956    191 QGDYEEAIAALERALEQD------PDYLPALPRLAELYEKLGDPEEALELLRKALELDPSddllLALADLLERKEGLEAA 264


                   ....*.
gi 1477471259 1026 RMFLLR 1031
Cdd:COG2956    265 LALLER 270
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 654-973 2.19e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.64  E-value: 2.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  654 RALAILRARPGgadgrvHTKEAIAYLSLAiFAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRAL 733
Cdd:TIGR02917  537 LALAGLYLRTG------NEEEAVAWLEKA-AELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGR 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  734 VHLALDQLQEAVDDIVSALKLGPGTVVPELR--------SLKPEAQALITQGLYSHCRALLSQLPDTGAPLEDKDTQGLL 805
Cdd:TIGR02917  610 AQLAAGDLNKAVSSFKKLLALQPDSALALLLladayavmKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAK 689

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  806 AVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAArARLGLLQLKKGDVPGAARDLQSLAEVDAP 885
Cdd:TIGR02917  690 KIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA-IKLHRALLASGNTAEAVKTLEAWLKTHPN 768

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  886 DLSCLLHLLEASERQSLAQAAAQEAGTLLDAgQPRQALGYCSLSVLA---SGSSACHLRLRA---------------TCL 947
Cdd:TIGR02917  769 DAVLRTALAELYLAQKDYDKAIKHYQTVVKK-APDNAVVLNNLAWLYlelKDPRALEYAERAlklapnipaildtlgWLL 847

                          330       340
                   ....*....|....*....|....*.
gi 1477471259  948 AELQEFGRALRDLDHVLQEALGDGDL 973
Cdd:TIGR02917  848 VEKGEADRALPLLRKAVNIAPEAAAI 873
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 673-1058 2.21e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.64  E-value: 2.21e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  673 KEAIAYLSLAIFAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSAL 752
Cdd:TIGR02917  107 QQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  753 KLGPGTVvpelrslkpeaQALITQGLYshcraLLSQlpdtgapledKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQ 832
Cdd:TIGR02917  187 TADPGNV-----------DALLLKGDL-----LLSL----------GNIELALAAYRKAIALRPNNIAVLLALATILIEA 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  833 GSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVdAPDLSCLLHLLEASE--RQSLAQAAAQ-- 908
Cdd:TIGR02917  241 GEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKS-APEYLPALLLAGASEyqLGNLEQAYQYln 319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  909 ---------------EAGTLLDAGQPRQALGYCSLSVLASGSSACHLRLRATCLAELQEFGRALRDLDHVLQEAlgdgdl 973
Cdd:TIGR02917  320 qilkyapnshqarrlLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELD------ 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  974 PRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPSL-----------------------AQNSLCRQPGRAPTarmFLL 1030
Cdd:TIGR02917  394 PENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELgradlllilsylrsgqfdkalaaAKKLEKKQPDNASL---HNL 470

                          410       420
                   ....*....|....*....|....*...
gi 1477471259 1031 RGQCCLEEQRHAEAWTAVESGLLVDPDH 1058
Cdd:TIGR02917  471 LGAIYLGKGDLAKAREAFEKALSIEPDF 498
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 794-913 3.58e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 3.58e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  794 APLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAA 873
Cdd:COG4783     13 ALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEAL 92

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1477471259  874 RDLQSLAEVDAPDLSCLLHL---LEASERQSLAQAAAQEAGTL 913
Cdd:COG4783     93 ALLEKALKLDPEHPEAYLRLaraYRALGRPDEAIAALEKALEL 135
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 688-850 2.26e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 2.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  688 SQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGtvvpELRSLK 767
Cdd:COG4783      1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD----EPEARL 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  768 PEAQALITQGLYSHCRALLsqlpdtgapledkdtqgllavgEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALH 847
Cdd:COG4783     77 NLGLALLKAGDYDEALALL----------------------EKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134


                   ...
gi 1477471259  848 RAP 850
Cdd:COG4783    135 LDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
718-980 8.17e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.63  E-value: 8.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  718 LRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGtvvpelrslkpEAQALITQGLyshcrALLSQlpdtgaple 797
Cdd:COG0457      1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD-----------DAEALYNLGL-----AYLRL--------- 55

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  798 dKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQ 877
Cdd:COG0457     56 -GRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYE 134

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  878 SLAEVDAPDLSCLLHLLEASERQSLAQAAAQEAGTLLDAGQPRQALGYCSLSVLASGSSACHLRLRATCLAELQEFGRAL 957
Cdd:COG0457    135 RALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAIL 214

                          250       260
                   ....*....|....*....|...
gi 1477471259  958 RDLDHVLQEALGDGDLPRRAEDF 980
Cdd:COG0457    215 TLAALAELLLLALALLLALRLAA 237
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-900 5.88e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.93  E-value: 5.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  556 MELDSEDEASRLLAADALYRLGRLEETHKALLVALSRRPQAAPVLARLALLQLRRGFFYDANQLVKKLVQSGD---TACL 632
Cdd:TIGR02917  220 IALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPeylPALL 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  633 QPTLDVFCHEDRQLLQGHCHA------------RALAILRARPGGADgrvhtkEAIAYLSLAIF------AAGSQASESL 694
Cdd:TIGR02917  300 LAGASEYQLGNLEQAYQYLNQilkyapnshqarRLLASIQLRLGRVD------EAIATLSPALGldpddpAALSLLGEAY 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  695 LArarcygfLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVVPELrslkpeaqALI 774
Cdd:TIGR02917  374 LA-------LGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADL--------LLI 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  775 TQGLYSHcrallsqlpdtgapLEDKdtqgLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEA 854
Cdd:TIGR02917  439 LSYLRSG--------------QFDK----ALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFP 500

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1477471259  855 ARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQ 900
Cdd:TIGR02917  501 AAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRT 546
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
674-918 8.72e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.55  E-value: 8.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  674 EAIAYLSLAIfAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALK 753
Cdd:COG0457     26 EAIEDYEKAL-ELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  754 LGPGTVVPeLRSLkpeAQALITQGLYSHCRALLSQLpdtgapledkdtqgllavgealIKIDSGQPHWHLLLADILMAQG 833
Cdd:COG0457    105 LDPDDAEA-LYNL---GLALLELGRYDEAIEAYERA----------------------LELDPDDADALYNLGIALEKLG 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  834 SYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQEAGTL 913
Cdd:COG0457    159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAAL 238


                   ....*
gi 1477471259  914 LDAGQ 918
Cdd:COG0457    239 ALYQY 243
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 823-1071 8.73e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.65  E-value: 8.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  823 LLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLleaserqsl 902
Cdd:COG2956     12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLEL--------- 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  903 aqaaaqeAGTLLDAGQPRQALGYCSLSVLASGSSACHLRLRATCLAELQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCR 982
Cdd:COG2956     83 -------AQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG------PENAHAYCE 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  983 QGRLLLSLGDEAAAAGAFAQALKLAPSLaqnslcrqpgraptARMFLLRGQCCLEEQRHAEAWTAVESGLLVDPDHRGLK 1062
Cdd:COG2956    150 LAELYLEQGDYDEAIEALEKALKLDPDC--------------ARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215


                   ....*....
gi 1477471259 1063 RLKARIRRE 1071
Cdd:COG2956    216 PRLAELYEK 224
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 818-1072 2.12e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.92  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  818 QPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLleas 897
Cdd:COG3914      2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLL---- 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  898 erqslAQAAAQEAGTLLDAGQPRQALGYCSLSVLASGSSACHLRLRATCLAELQEFGRALRDLDHVLQEAlgdgdlPRRA 977
Cdd:COG3914     78 -----AALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN------PDFA 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  978 EDFCRQGRLLLSLGDEAAAAGAFAQALKLAPSLAQnslcrqpgraptarMFLLRGQCCLEEQRHAEAWTAVESGLLVDPD 1057
Cdd:COG3914    147 EAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE--------------ALNNLGNALQDLGRLEEAIAAYRRALELDPD 212

                          250
                   ....*....|....*
gi 1477471259 1058 HRGLKRLKARIRREA 1072
Cdd:COG3914    213 NADAHSNLLFALRQA 227
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 652-942 2.33e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.53  E-value: 2.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  652 HARALAILRARPGGADGRVHTKEAIAYLSLAIFAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGR 731
Cdd:COG3914      5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  732 ALVHLALDQLQEAVDDIVSALKLGPGtvvpelrslkpEAQALITQGlyshcrALLSQLpdtgapledKDTQGLLAVGEAL 811
Cdd:COG3914     85 ALLLQALGRYEEALALYRRALALNPD-----------NAEALFNLG------NLLLAL---------GRLEEALAALRRA 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  812 IKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLL 891
Cdd:COG3914    139 LALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHS 218

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1477471259  892 HLLEASERQSLAQAAAQEAGTLLDAGQPRQALGYCSLSVLASGSSACHLRL 942
Cdd:COG3914    219 NLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELLAL 269
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
673-864 8.95e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.46  E-value: 8.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  673 KEAIAYLSLAIfAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSAL 752
Cdd:COG0457     59 EEALADYEQAL-ELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERAL 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  753 KLGPGTVvpelRSLKPEAQALITQGLYSHCRALLSQLPDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQ 832
Cdd:COG0457    138 ELDPDDA----DALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAI 213

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1477471259  833 GSYEEAGTHLEKALHRAPTSEAARARLGLLQL 864
Cdd:COG0457    214 LTLAALAELLLLALALLLALRLAALALYQYRA 245
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 804-923 1.01e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  804 LLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVD 883
Cdd:COG4235      2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1477471259  884 APDLSCLLHL---LEASERQSLAQAAAQEAGTLLDAGQPRQAL 923
Cdd:COG4235     82 PDNPEALYLLglaAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 675-879 1.28e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 1.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  675 AIAYLSLAIFAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQA--LCGRALvhLALDQLQEAVDDIVSAL 752
Cdd:TIGR02917    6 ALLCIALALSACGDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEArfLLGKIY--LALGDYAAAEKELRKAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  753 KLG--PGTVVPEL-RSL----------------------------------------KPEAQALITQGLYSHCRALLSQL 789
Cdd:TIGR02917   84 SLGypKNQVLPLLaRAYllqgkfqqvldelpgktllddegaaellalrglaylglgqLELAQKSYEQALAIDPRSLYAKL 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  790 PDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDV 869
Cdd:TIGR02917  164 GLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEF 243

                          250
                   ....*....|
gi 1477471259  870 PGAARDLQSL 879
Cdd:TIGR02917  244 EEAEKHADAL 253
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
653-757 1.39e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.60  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  653 ARALAILRARPGGADGRVHTKEAIAYLSLAIFAAGSQAsESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRA 732
Cdd:COG4785     36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLA-QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRG 114

                           90       100
                   ....*....|....*....|....*
gi 1477471259  733 LVHLALDQLQEAVDDIVSALKLGPG 757
Cdd:COG4785    115 LAYLLLGDYDAALEDFDRALELDPD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 716-857 2.60e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 2.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  716 TVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTvvPELRSLKpeAQALITQGLYSHCRALLsqlpdtgap 795
Cdd:COG4235      8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN--ADALLDL--AEALLAAGDTEEAEELL--------- 74

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1477471259  796 ledkdtqgllavgEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARA 857
Cdd:COG4235     75 -------------ERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
812-925 1.20e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.52  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  812 IKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDA--PDLSC 889
Cdd:COG4785    100 LELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPndPERAL 179

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1477471259  890 LLHLLEASERQSLAQAAAQE--AGTLLDAGQPRQALGY 925
Cdd:COG4785    180 WLYLAERKLDPEKALALLLEdwATAYLLQGDTEEAREL 217
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
809-884 1.47e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.69  E-value: 1.47e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1477471259  809 EALIKIDSGQPHWHLLLADILMAQGSYEEAGThLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDA 884
Cdd:COG3063     16 EKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
697-756 3.69e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 3.69e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  697 RARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGP 756
Cdd:COG4785    113 RGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDP 172
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 803-1069 4.24e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 4.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  803 GLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEV 882
Cdd:TIGR02917    6 ALLCIALALSACGDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  883 DAPDLSCLLHLLEASERQSLAQAAAQEAG--TLLDAGQPRQALGYCSLSVLASG-----------------SSACHLRLR 943
Cdd:TIGR02917   86 GYPKNQVLPLLARAYLLQGKFQQVLDELPgkTLLDDEGAAELLALRGLAYLGLGqlelaqksyeqalaidpRSLYAKLGL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  944 ATCLAELQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPslaqnslcrqpgRAP 1023
Cdd:TIGR02917  166 AQLALAENRFDEARALIDEVLTAD------PGNVDALLLKGDLLLSLGNIELALAAYRKAIALRP------------NNI 227

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1477471259 1024 TARMFLlrGQCCLEEQRHAEAWTAVESGLLVDPDHRGLKRLKARIR 1069
Cdd:TIGR02917  228 AVLLAL--ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD 271
COG3903 COG3903
Predicted ATPase [General function prediction only];
131-533 6.76e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.85  E-value: 6.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  131 SHAQQVLELRLTRALAWVLSGVQAADGVAAYLQAFASSADRTVAfirthqrphlPALLSALQDYLSGHPEAGHSAGQQET 210
Cdd:COG3903    537 AHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAA----------ALAAAAALAAAAAAARAAAAAAAAAA 606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  211 GGQRLLAALDPRGTRSDTLSPEALLHSGRFEDCLAACSRALEAHPTGSEPQGERRAALLVTRAASAFFLDGRAQDVFWNL 290
Cdd:COG3903    607 AAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAA 686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  291 QEAFRESPSGARRQFQAVFSVQDQERVRAQAQEAADVGFARFQEAVRNHPELREDAGRELLAPVTRALRVLLRLAPAGAR 370
Cdd:COG3903    687 LAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAA 766

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  371 PALGARLAECLLLAGDAAGARAMCERLLRPARPEDPAGDRAGDRAPLLALRGFCALHAGDSRRAMEDFQTVVEQGAPHPG 450
Cdd:COG3903    767 AAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAA 846

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  451 GCVRALCGRGLLRVLAGSAFLGTLDYVTACRLRPEEALLAAKAYVPWNQRGLLLVVLREEARGMLQRSPRAGPSRAQGRR 530
Cdd:COG3903    847 AAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAA 926


                   ...
gi 1477471259  531 EAA 533
Cdd:COG3903    927 AAA 929
COG3903 COG3903
Predicted ATPase [General function prediction only];
235-597 8.29e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.47  E-value: 8.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  235 LHSGRFEDCLAACSRALEAHPTGSEPQGERRAALLVTRAASAFFLDGRAQDVFWNLQEAFRESPSGARRQFQAVFSVQDQ 314
Cdd:COG3903    556 FLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAA 635

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  315 ERVRAQAQEAADVGFARFQEAVRNHPELREDAGRELLAPVTRALRVLLRLAPAGARPALGARLAECLLLAGDAAGARAMC 394
Cdd:COG3903    636 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAA 715

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  395 ERLLRPARPEDPAGDRAGDRAPLLALRGFCALHAGDSRRAMEDFQTVVEQGAPHPGGCVRALCGRGLLRVLAGSAFLGTL 474
Cdd:COG3903    716 AAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAA 795

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  475 DYVTACRLRPEEALLAAKAYVPWNQRGLLLVVLREEARGMLQRSPRAGPSRAQGRREAAETGGPTTQEGVACGVHQLATL 554
Cdd:COG3903    796 AAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAA 875

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1477471259  555 LMELDSEDEASRLLAADALYRLGRLEETHKALLVALSRRPQAA 597
Cdd:COG3903    876 AAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALA 918
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 822-881 1.08e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 1.08e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1477471259  822 HLLLADILMAQGSYEEAGTHLEKALHRAPTSE---AARARLGLLQLKKGDVPGAARDLQSLAE 881
Cdd:COG1729     33 LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELGDYDKARATLEELIK 95
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 796-883 1.57e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.33  E-value: 1.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  796 LEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARD 875
Cdd:COG5010     65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144


                   ....*...
gi 1477471259  876 LQSLAEVD 883
Cdd:COG5010    145 LQRALGTS 152
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 769-1047 1.88e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.29  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  769 EAQALITQGLYSHCRALLSQLPDTGAPLEDKDTQGLLAVGEALIKIDSGQP---HWHLLLADILMAQGSYEEAGTHLEKA 845
Cdd:COG3914     25 ELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLllaALLELAALLLQALGRYEEALALYRRA 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  846 LHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDapdlscllhlleaserqslaqaaaqeagtlldagqPRQALGY 925
Cdd:COG3914    105 LALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN-----------------------------------PDFAEAY 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  926 CSLsvlasgssachlrlrATCLAELQEFGRALRDLDHVLQEAlgdgdlPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALK 1005
Cdd:COG3914    150 LNL---------------GEALRRLGRLEEAIAALRRALELD------PDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1477471259 1006 LAPSLAQnslcrqpgrAPTARMFLLRGQCCLEEQRHAEAWTA 1047
Cdd:COG3914    209 LDPDNAD---------AHSNLLFALRQACDWEVYDRFEELLA 241
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 555-881 2.19e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  555 LMELDSEDEASRLLAADALYRLGRLEETHKALLVALSRRPQAAPVLARLALLQLRRGFFYDANQLVKKLVQSGDtaclqp 634
Cdd:COG2956     34 ALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDP------ 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  635 tldvfchedrqllqghcharalailrarpggadgrvhtkeaiaylslaifaagsQASESLLARARCYGFLGQKKTAMFDF 714
Cdd:COG2956    108 ------------------------------------------------------DDAEALRLLAEIYEQEGDWEKAIEVL 133

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  715 NTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVvpelrslkpEAQALITQgLYshcrallsqlpdtga 794
Cdd:COG2956    134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA---------RALLLLAE-LY--------------- 188

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  795 pLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARArLGLLQLKKGDVPGAAR 874
Cdd:COG2956    189 -LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEAALA 266


                   ....*..
gi 1477471259  875 DLQSLAE 881
Cdd:COG2956    267 LLERQLR 273
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 820-900 3.51e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 40.95  E-value: 3.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  820 HWHLLLADILMAQGSYEEAGTHLEKALHRAPTSeaARAR--LGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEAS 897
Cdd:PRK11788   181 HFYCELAQQALARGDLDAARALLKKALAADPQC--VRASilLGDLALAQGDYAAAIEALERVEEQDPEYLSEVLPKLMEC 258


                   ...
gi 1477471259  898 ERQ 900
Cdd:PRK11788   259 YQA 261
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 768-915 7.04e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 7.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1477471259  768 PEAQALITQGLYSHCRALLSQLPDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALH 847
Cdd:COG5010      3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1477471259  848 RAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQEAGTLLD 915
Cdd:COG5010     83 LDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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