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Conserved domains on  [gi|338968860|ref|NP_001229797|]
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SLAIN motif-containing protein 1 isoform C [Homo sapiens]

Protein Classification

SLAIN motif-containing protein( domain architecture ID 12172998)

SLAIN motif-containing protein is a microtubule plus-end tracking protein, similar to human SLAIN2 that binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 209-590 6.80e-123

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


:

Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 369.04  E-value: 6.80e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  209 WLYIgSSKTFTSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQ--------------------------------- 255
Cdd:pfam15301   1 WLYV-SPKKKVPSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQasrwrslysspsssssaysgnaeassyssglns 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  256 -----------------GYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASV 318
Cdd:pfam15301  80 pgylkstnkqlltcgssGYLRRHSALSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  319 SRHSSSVSLSSGKKGTCSDQEYDQYSLEDEEEFDhlpppqprlprCSPFQRGIPH--SQTFSSIRECRRSPSsqyfPSNN 396
Cdd:pfam15301 160 SRRSSSFSLHSLRRGTYSDQELDAYSLEDEEEEY-----------CSLPQPRLHRfsPLPHSSPRDSPRSRS----PSTS 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  397 YQQQQYYSPQAQTP---------DQQPNRTNGDKLRRSMPNLARMPSttaissnISSPVTVRNSQSFDSSLHGAGNGISR 467
Cdd:pfam15301 225 QEYSRLSAQRLRQPrrslqgpgaELQKYAKSEEKLRRSMPNLARRTS-------LRSLESVRNSRSFESNLQVPNSGLSR 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  468 IQ---SCIPSPgqLQHRVHSVGHFPVSIRQPLKATAYVSPTVQGSSN-MPLSNGLQLYSNTGIPTPNKAAASGIMGRSAL 543
Cdd:pfam15301 298 LQqssSSIPSP--SKLRVQSAGQSPLALRQPVKATSYVSSTVAGPSKgLPSSQSLPSGGSSGSPLPSRPSGGYSGGRSSL 375

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 338968860  544 PRPSLAING-SNLPRSKIAQPVRSFLQPPKplsSLSTLRDGNWRDGCY 590
Cdd:pfam15301 376 PRPASFVGGtSPVPRSKLAQPVRRSLTPPK---TYSALRDESWKDGCY 420
 
Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 209-590 6.80e-123

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 369.04  E-value: 6.80e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  209 WLYIgSSKTFTSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQ--------------------------------- 255
Cdd:pfam15301   1 WLYV-SPKKKVPSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQasrwrslysspsssssaysgnaeassyssglns 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  256 -----------------GYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASV 318
Cdd:pfam15301  80 pgylkstnkqlltcgssGYLRRHSALSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  319 SRHSSSVSLSSGKKGTCSDQEYDQYSLEDEEEFDhlpppqprlprCSPFQRGIPH--SQTFSSIRECRRSPSsqyfPSNN 396
Cdd:pfam15301 160 SRRSSSFSLHSLRRGTYSDQELDAYSLEDEEEEY-----------CSLPQPRLHRfsPLPHSSPRDSPRSRS----PSTS 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  397 YQQQQYYSPQAQTP---------DQQPNRTNGDKLRRSMPNLARMPSttaissnISSPVTVRNSQSFDSSLHGAGNGISR 467
Cdd:pfam15301 225 QEYSRLSAQRLRQPrrslqgpgaELQKYAKSEEKLRRSMPNLARRTS-------LRSLESVRNSRSFESNLQVPNSGLSR 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  468 IQ---SCIPSPgqLQHRVHSVGHFPVSIRQPLKATAYVSPTVQGSSN-MPLSNGLQLYSNTGIPTPNKAAASGIMGRSAL 543
Cdd:pfam15301 298 LQqssSSIPSP--SKLRVQSAGQSPLALRQPVKATSYVSSTVAGPSKgLPSSQSLPSGGSSGSPLPSRPSGGYSGGRSSL 375

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 338968860  544 PRPSLAING-SNLPRSKIAQPVRSFLQPPKplsSLSTLRDGNWRDGCY 590
Cdd:pfam15301 376 PRPASFVGGtSPVPRSKLAQPVRRSLTPPK---TYSALRDESWKDGCY 420
 
Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 209-590 6.80e-123

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 369.04  E-value: 6.80e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  209 WLYIgSSKTFTSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQ--------------------------------- 255
Cdd:pfam15301   1 WLYV-SPKKKVPSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQasrwrslysspsssssaysgnaeassyssglns 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  256 -----------------GYTSRGSPLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASV 318
Cdd:pfam15301  80 pgylkstnkqlltcgssGYLRRHSALSPQSSVDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  319 SRHSSSVSLSSGKKGTCSDQEYDQYSLEDEEEFDhlpppqprlprCSPFQRGIPH--SQTFSSIRECRRSPSsqyfPSNN 396
Cdd:pfam15301 160 SRRSSSFSLHSLRRGTYSDQELDAYSLEDEEEEY-----------CSLPQPRLHRfsPLPHSSPRDSPRSRS----PSTS 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  397 YQQQQYYSPQAQTP---------DQQPNRTNGDKLRRSMPNLARMPSttaissnISSPVTVRNSQSFDSSLHGAGNGISR 467
Cdd:pfam15301 225 QEYSRLSAQRLRQPrrslqgpgaELQKYAKSEEKLRRSMPNLARRTS-------LRSLESVRNSRSFESNLQVPNSGLSR 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338968860  468 IQ---SCIPSPgqLQHRVHSVGHFPVSIRQPLKATAYVSPTVQGSSN-MPLSNGLQLYSNTGIPTPNKAAASGIMGRSAL 543
Cdd:pfam15301 298 LQqssSSIPSP--SKLRVQSAGQSPLALRQPVKATSYVSSTVAGPSKgLPSSQSLPSGGSSGSPLPSRPSGGYSGGRSSL 375

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 338968860  544 PRPSLAING-SNLPRSKIAQPVRSFLQPPKplsSLSTLRDGNWRDGCY 590
Cdd:pfam15301 376 PRPASFVGGtSPVPRSKLAQPVRRSLTPPK---TYSALRDESWKDGCY 420
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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