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Conserved domains on  [gi|359806886|ref|NP_001240829|]
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mesoderm-specific transcript homolog protein isoform c [Homo sapiens]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 58-320 5.70e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 97.38  E-value: 5.70e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  58 VVLLHGFPTSSYDWYKIWEGLTLRFhRVIALDFLGFGFSDKPRPhHYSIFEQASIVEALLRHLGLQnrRINLLSHDYGDI 137
Cdd:COG0596   26 VVLLHGLPGSSYEWRPLIPALAAGY-RVIAPDLRGHGRSDKPAG-GYTLDDLADDLAALLDALGLE--RVVLVGHSMGGM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886 138 VAQELLYRYKQNrsgrltIKSLCLSNggifpETHRplLLQKLLKDGGVLSPILTRLMNFFVfsrgltpvfgpytrpsese 217
Cdd:COG0596  102 VALELAARHPER------VAGLVLVD-----EVLA--ALAEPLRRPGLAPEALAALLRALA------------------- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886 218 LWDMWAgirnndgnlvidsllqyinqrkkfrrrwvgALASVTIPIHFIYGPLDPVNPyPEFLELYRKTLPRSTVSILDDh 297
Cdd:COG0596  150 RTDLRE------------------------------RLARITVPTLVIWGEKDPIVP-PALARRLAELLPNAELVVLPG- 197

                        250       260
                 ....*....|....*....|...
gi 359806886 298 ISHYPQLEDPMGFLNAYMGFINS 320
Cdd:COG0596  198 AGHFPPLEQPEAFAAALRDFLAR 220
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 58-320 5.70e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 97.38  E-value: 5.70e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  58 VVLLHGFPTSSYDWYKIWEGLTLRFhRVIALDFLGFGFSDKPRPhHYSIFEQASIVEALLRHLGLQnrRINLLSHDYGDI 137
Cdd:COG0596   26 VVLLHGLPGSSYEWRPLIPALAAGY-RVIAPDLRGHGRSDKPAG-GYTLDDLADDLAALLDALGLE--RVVLVGHSMGGM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886 138 VAQELLYRYKQNrsgrltIKSLCLSNggifpETHRplLLQKLLKDGGVLSPILTRLMNFFVfsrgltpvfgpytrpsese 217
Cdd:COG0596  102 VALELAARHPER------VAGLVLVD-----EVLA--ALAEPLRRPGLAPEALAALLRALA------------------- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886 218 LWDMWAgirnndgnlvidsllqyinqrkkfrrrwvgALASVTIPIHFIYGPLDPVNPyPEFLELYRKTLPRSTVSILDDh 297
Cdd:COG0596  150 RTDLRE------------------------------RLARITVPTLVIWGEKDPIVP-PALARRLAELLPNAELVVLPG- 197

                        250       260
                 ....*....|....*....|...
gi 359806886 298 ISHYPQLEDPMGFLNAYMGFINS 320
Cdd:COG0596  198 AGHFPPLEQPEAFAAALRDFLAR 220
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 58-307 6.52e-21

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 89.87  E-value: 6.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886   58 VVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPR-PHHYSIFEQASIVEALLRHLGLQnrRINLLSHDYGD 136
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKaQDDYRTDDLAEDLEYILEALGLE--KVNLVGHSMGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  137 IVAQELLYRYKQNrsgrltIKSLCLSNGGIFPETHRPLLLQKLLKD----GGVLSPILTRLMNFFV-FSRGLTPVFGPYT 211
Cdd:pfam00561  81 LIALAYAAKYPDR------VKALVLLGALDPPHELDEADRFILALFpgffDGFVADFAPNPLGRLVaKLLALLLLRLRLL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  212 RPSESELWDMWAGIRNNDGNLVIDSLLQYINQRKKFRRRWVGALAsvtIPIHFIYGPLDPVNPyPEFLELYRKTLPRSTV 291
Cdd:pfam00561 155 KALPLLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRLD---EPTLIIWGDQDPLVP-PQALEKLAQLFPNARL 230

                         250
                  ....*....|....*.
gi 359806886  292 sILDDHISHYPQLEDP 307
Cdd:pfam00561 231 -VVIPDAGHFAFLEGP 245
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 53-135 2.64e-12

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 66.17  E-value: 2.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  53 GSPEIVVLLHGFPTSSYDWYKIWEGLTlRFHRVIALDFLGFGFSDKPrPHHYSIFEQASIVEALLRHLGLqnRRINLLSH 132
Cdd:PRK03592  25 GEGDPIVFLHGNPTSSYLWRNIIPHLA-GLGRCLAPDLIGMGASDKP-DIDYTFADHARYLDAWFDALGL--DDVVLVGH 100


                 ...
gi 359806886 133 DYG 135
Cdd:PRK03592 101 DWG 103
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 58-320 5.70e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 97.38  E-value: 5.70e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  58 VVLLHGFPTSSYDWYKIWEGLTLRFhRVIALDFLGFGFSDKPRPhHYSIFEQASIVEALLRHLGLQnrRINLLSHDYGDI 137
Cdd:COG0596   26 VVLLHGLPGSSYEWRPLIPALAAGY-RVIAPDLRGHGRSDKPAG-GYTLDDLADDLAALLDALGLE--RVVLVGHSMGGM 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886 138 VAQELLYRYKQNrsgrltIKSLCLSNggifpETHRplLLQKLLKDGGVLSPILTRLMNFFVfsrgltpvfgpytrpsese 217
Cdd:COG0596  102 VALELAARHPER------VAGLVLVD-----EVLA--ALAEPLRRPGLAPEALAALLRALA------------------- 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886 218 LWDMWAgirnndgnlvidsllqyinqrkkfrrrwvgALASVTIPIHFIYGPLDPVNPyPEFLELYRKTLPRSTVSILDDh 297
Cdd:COG0596  150 RTDLRE------------------------------RLARITVPTLVIWGEKDPIVP-PALARRLAELLPNAELVVLPG- 197

                        250       260
                 ....*....|....*....|...
gi 359806886 298 ISHYPQLEDPMGFLNAYMGFINS 320
Cdd:COG0596  198 AGHFPPLEQPEAFAAALRDFLAR 220
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 58-307 6.52e-21

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 89.87  E-value: 6.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886   58 VVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPR-PHHYSIFEQASIVEALLRHLGLQnrRINLLSHDYGD 136
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKaQDDYRTDDLAEDLEYILEALGLE--KVNLVGHSMGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  137 IVAQELLYRYKQNrsgrltIKSLCLSNGGIFPETHRPLLLQKLLKD----GGVLSPILTRLMNFFV-FSRGLTPVFGPYT 211
Cdd:pfam00561  81 LIALAYAAKYPDR------VKALVLLGALDPPHELDEADRFILALFpgffDGFVADFAPNPLGRLVaKLLALLLLRLRLL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  212 RPSESELWDMWAGIRNNDGNLVIDSLLQYINQRKKFRRRWVGALAsvtIPIHFIYGPLDPVNPyPEFLELYRKTLPRSTV 291
Cdd:pfam00561 155 KALPLLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRLD---EPTLIIWGDQDPLVP-PQALEKLAQLFPNARL 230

                         250
                  ....*....|....*.
gi 359806886  292 sILDDHISHYPQLEDP 307
Cdd:pfam00561 231 -VVIPDAGHFAFLEGP 245
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 53-135 2.64e-12

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 66.17  E-value: 2.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  53 GSPEIVVLLHGFPTSSYDWYKIWEGLTlRFHRVIALDFLGFGFSDKPrPHHYSIFEQASIVEALLRHLGLqnRRINLLSH 132
Cdd:PRK03592  25 GEGDPIVFLHGNPTSSYLWRNIIPHLA-GLGRCLAPDLIGMGASDKP-DIDYTFADHARYLDAWFDALGL--DDVVLVGH 100


                 ...
gi 359806886 133 DYG 135
Cdd:PRK03592 101 DWG 103
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 35-140 5.35e-11

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 62.98  E-value: 5.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  35 QLSPALHSWKSSDSvGVVGSPEiVVLLHGFPTSSYDWYKIWEGLTLRFHrVIALDFLGFGFSDKPRPHH---YSIFEQAS 111
Cdd:PLN03084 109 QASSDLFRWFCVES-GSNNNPP-VLLIHGFPSQAYSYRKVLPVLSKNYH-AIAFDWLGFGFSDKPQPGYgfnYTLDEYVS 185

                         90       100
                 ....*....|....*....|....*....
gi 359806886 112 IVEALlrhlglqnrrINLLSHDYGDIVAQ 140
Cdd:PLN03084 186 SLESL----------IDELKSDKVSLVVQ 204
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 31-135 2.49e-10

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 60.26  E-value: 2.49e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  31 IPPPQLSPALHSWKSSdSVGVV-----GSPEIVVLLHGFPTSSYDWYKIWEGLTLRFhRVIALDFLGFGFSDKPRPHHYS 105
Cdd:PRK03204   6 TPDPQLYPFESRWFDS-SRGRIhyideGTGPPILLCHGNPTWSFLYRDIIVALRDRF-RCVAPDYLGFGLSERPSGFGYQ 83

                         90       100       110
                 ....*....|....*....|....*....|
gi 359806886 106 IFEQASIVEALLRHLGLQNrrINLLSHDYG 135
Cdd:PRK03204  84 IDEHARVIGEFVDHLGLDR--YLSMGQDWG 111
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 56-138 9.78e-09

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 55.74  E-value: 9.78e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  56 EIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKP-RPHHYSIFEQASIVEALLRHLGLQNrrINLLSHDY 134
Cdd:PRK00870  47 PPVLLLHGEPSWSYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPtRREDYTYARHVEWMRSWFEQLDLTD--VTLVCQDW 124


                 ....
gi 359806886 135 GDIV 138
Cdd:PRK00870 125 GGLI 128
PRK05855 PRK05855
SDR family oxidoreductase;
41-145 7.12e-07

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 50.75  E-value: 7.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  41 HSWKSSD----SVGVVGSPE--IVVLLHGFPTSSYDWYKIWEGLTLRFHrVIALDFLGFGFSDKPRPHH-YSIFEQASIV 113
Cdd:PRK05855   5 RTVVSSDgvrlAVYEWGDPDrpTVVLVHGYPDNHEVWDGVAPLLADRFR-VVAYDVRGAGRSSAPKRTAaYTLARLADDF 83

                         90       100       110
                 ....*....|....*....|....*....|..
gi 359806886 114 EALLRHLGlQNRRINLLSHDYGDIVAQELLYR 145
Cdd:PRK05855  84 AAVIDAVS-PDRPVHLLAHDWGSIQGWEAVTR 114
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
57-146 1.59e-06

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 48.07  E-value: 1.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  57 IVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPRPHHYSIFEQASIVEALLRHLGLQ-NRRINLLSHDYG 135
Cdd:COG2267   30 TVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAALDALRARpGLPVVLLGHSMG 109

                         90
                 ....*....|.
gi 359806886 136 DIVAQELLYRY 146
Cdd:COG2267  110 GLIALLYAARY 120
PLN02578 PLN02578
hydrolase
 53-98 2.38e-06

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 48.68  E-value: 2.38e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 359806886  53 GSPeiVVLLHGFPTSSYDW-YKIWEglTLRFHRVIALDFLGFGFSDK 98
Cdd:PLN02578  86 GLP--IVLIHGFGASAFHWrYNIPE--LAKKYKVYALDLLGFGWSDK 128
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 53-101 3.49e-06

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 47.81  E-value: 3.49e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 359806886  53 GSPEIVVLLHGFPTSSYDWYKIWEGLTLRfHRVIALDFLGFGFSDKPRP 101
Cdd:PLN02824  27 TSGPALVLVHGFGGNADHWRKNTPVLAKS-HRVYAIDLLGYGYSDKPNP 74
PLN03087 PLN03087
BODYGUARD 1 domain containing hydrolase; Provisional
 41-161 9.22e-06

BODYGUARD 1 domain containing hydrolase; Provisional


Pssm-ID: 215567  Cd Length: 481  Bit Score: 47.11  E-value: 9.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  41 HSWKSSDS----VGVVGSP-----EIVVLLHGFPTSSYDWYkiwEGLTLRF-------HRVIALDFLGFGFSDKPRPHHY 104
Cdd:PLN03087 178 TSWLSSSNeslfVHVQQPKdnkakEDVLFIHGFISSSAFWT---ETLFPNFsdaakstYRLFAVDLLGFGRSPKPADSLY 254

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 359806886 105 SIFEQASIVE-ALLRHLGLqnRRINLLSHDYGDIVAQELLYRYKQnrsgrlTIKSLCL 161
Cdd:PLN03087 255 TLREHLEMIErSVLERYKV--KSFHIVAHSLGCILALALAVKHPG------AVKSLTL 304
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 58-147 1.67e-05

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 45.16  E-value: 1.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886   58 VVLLHGFPTSSYDWykiwEGLTLRFHRVIALDFLGFGFSDkPRPHHYSIFEQasiVEALLRHLGLQNRRInLLSHDYGDI 137
Cdd:pfam12697   1 VVLVHGAGLSAAPL----AALLAAGVAVLAPDLPGHGSSS-PPPLDLADLAD---LAALLDELGAARPVV-LVGHSLGGA 71

                          90
                  ....*....|
gi 359806886  138 VAQELLYRYK 147
Cdd:pfam12697  72 VALAAAAAAL 81
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 53-187 5.12e-04

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 41.47  E-value: 5.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  53 GSPEIVVLLHGFPTSSYDWYKIWEGLTlRFHRVIALDFLGFGFSDKpRPHHYSIFEQASIVEALLRHLGLQnrRINLLSH 132
Cdd:PRK14875 129 GDGTPVVLIHGFGGDLNNWLFNHAALA-AGRPVIALDLPGHGASSK-AVGAGSLDELAAAVLAFLDALGIE--RAHLVGH 204

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 359806886 133 DYGDIVAQELLyrykQNRSGRltIKSLCL-SNGGIFPE-------------THRPL--LLQKLLKDGGVLS 187
Cdd:PRK14875 205 SMGGAVALRLA----ARAPQR--VASLTLiAPAGLGPEingdyidgfvaaeSRRELkpVLELLFADPALVT 269
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 43-106 1.61e-03

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 39.82  E-value: 1.61e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 359806886  43 WKSSDSVG--VVGSPEI------VVLLHGFPTSSYDWYKIWEGLTlRFHRVIALDFLGFGFSDKPRPHHYSI 106
Cdd:PLN02679  68 WKGEYSINylVKGSPEVtssgppVLLVHGFGASIPHWRRNIGVLA-KNYTVYAIDLLGFGASDKPPGFSYTM 138
PRK08775 PRK08775
homoserine O-succinyltransferase;
49-158 4.93e-03

homoserine O-succinyltransferase;


Pssm-ID: 181553 [Multi-domain]  Cd Length: 343  Bit Score: 38.23  E-value: 4.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  49 VGVVGSPEIVVL--------LHGFPTSSYD-WykiWEGLT-------LRFHRVIALDFLGfgfSDKPRPHHYSIFEQASI 112
Cdd:PRK08775  53 IGPAGAPVVFVAggisahrhVAATATFPEKgW---WEGLVgsgraldPARFRLLAFDFIG---ADGSLDVPIDTADQADA 126

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 359806886 113 VEALLRHLGLQnRRINLLSHDYGDIVAQELLYRYKQnRSGRLTIKS 158
Cdd:PRK08775 127 IALLLDALGIA-RLHAFVGYSYGALVGLQFASRHPA-RVRTLVVVS 170
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 57-193 5.61e-03

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 37.58  E-value: 5.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886   57 IVVLLHGFpTSSYDWY-KIWEGLTLRFHRVIALDFLGFGFSDKPRPHHYSIFEQASIVEALLRHLGLQNRRIN--LLSHD 133
Cdd:pfam12146   6 VVVLVHGL-GEHSGRYaHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPlfLLGHS 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886  134 YGDIVAQELLYRYKQNrsgrltIKSLCLSNGGIFPETHRPLLLQKLLkdGGVLSPILTRL 193
Cdd:pfam12146  85 MGGLIAALYALRYPDK------VDGLILSAPALKIKPYLAPPILKLL--AKLLGKLFPRL 136
DUF1057 pfam06342
Alpha/beta hydrolase of unknown function (DUF1057); This family consists of several ...
 53-135 7.65e-03

Alpha/beta hydrolase of unknown function (DUF1057); This family consists of several Caenorhabditis elegans specific proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.


Pssm-ID: 115027  Cd Length: 297  Bit Score: 37.43  E-value: 7.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 359806886   53 GSPE-IVVLLHGFPTSSYDWYKI---WEGLTLRFhrvIALDFLGFGFSDKPRPHHYSIFEQASIVEALLRHLGLQNRRIn 128
Cdd:pfam06342  32 GSPFgTVVAFHGSPGSHNDFKYIrskFEDLNIRF---IGVNYPGFEFTTGYPGQSHTNQERNSYSKALLEELELKGKLI- 107


                  ....*..
gi 359806886  129 LLSHDYG 135
Cdd:pfam06342 108 IMGHSRG 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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