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Conserved domains on  [gi|368711277|ref|NP_001243023|]
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cyclic AMP-dependent transcription factor ATF-2 isoform 5 [Homo sapiens]

Protein Classification

GCN4_cent domain-containing protein( domain architecture ID 10187487)

GCN4_cent domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GCN4_cent cd12192
GCN4 central activation domain-like acidic activation domain; GCN4 was identified in ...
 65-102 7.57e-04

GCN4 central activation domain-like acidic activation domain; GCN4 was identified in Saccharomyces cerevisiae from mutations in a deficiency in activation with the general amino acid control pathway. GCN4 encodes a trans-activator of amino acid biosynthetic genes containing 2 acidic activation domains and a C-terminal bZIP domain, comprised of a basic alpha-helical DNA-binding region and a coiled-coil dimerization region.


:

Pssm-ID: 213399  Cd Length: 40  Bit Score: 36.22  E-value: 7.57e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 368711277  65 VADQTPTPTRfLKNCEEVGL---FNELASPFENEFKKASED 102
Cdd:cd12192    1 SADSTPMFDE-LDFIEDGGKvnsKDDWVSLFDDDIPATAED 40
 
Name Accession Description Interval E-value
GCN4_cent cd12192
GCN4 central activation domain-like acidic activation domain; GCN4 was identified in ...
 65-102 7.57e-04

GCN4 central activation domain-like acidic activation domain; GCN4 was identified in Saccharomyces cerevisiae from mutations in a deficiency in activation with the general amino acid control pathway. GCN4 encodes a trans-activator of amino acid biosynthetic genes containing 2 acidic activation domains and a C-terminal bZIP domain, comprised of a basic alpha-helical DNA-binding region and a coiled-coil dimerization region.


Pssm-ID: 213399  Cd Length: 40  Bit Score: 36.22  E-value: 7.57e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 368711277  65 VADQTPTPTRfLKNCEEVGL---FNELASPFENEFKKASED 102
Cdd:cd12192    1 SADSTPMFDE-LDFIEDGGKvnsKDDWVSLFDDDIPATAED 40
 
Name Accession Description Interval E-value
GCN4_cent cd12192
GCN4 central activation domain-like acidic activation domain; GCN4 was identified in ...
 65-102 7.57e-04

GCN4 central activation domain-like acidic activation domain; GCN4 was identified in Saccharomyces cerevisiae from mutations in a deficiency in activation with the general amino acid control pathway. GCN4 encodes a trans-activator of amino acid biosynthetic genes containing 2 acidic activation domains and a C-terminal bZIP domain, comprised of a basic alpha-helical DNA-binding region and a coiled-coil dimerization region.


Pssm-ID: 213399  Cd Length: 40  Bit Score: 36.22  E-value: 7.57e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 368711277  65 VADQTPTPTRfLKNCEEVGL---FNELASPFENEFKKASED 102
Cdd:cd12192    1 SADSTPMFDE-LDFIEDGGKvnsKDDWVSLFDDDIPATAED 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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