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Conserved domains on  [gi|371873730|ref|NP_001243102|]
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zinc finger protein 85 isoform d [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
164-525 5.35e-14

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 5.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 164 KPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKC--EECGKTFNRFSTLTTHKIIHTGEKPYKC-KECGKAFNRSSTLTTH 240
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 241 RKIHTGEKPYKCEECGKAFKQSSNLT--THKIIHTGEKPYK-CKKCGKAFNQSAHL-------------------TTHEV 298
Cdd:COG5048  112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLhpplpanslskdpssnlslLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 299 IHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLT 378
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 379 EHKKIHTGE-------KPYECEKCGKAFNQSSNLTRHKKS--HTEE--KPYKCEE--CGKGFKWPSTLTIHKIIHTGEKP 445
Cdd:COG5048  272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 446 YKC--EECGKAFNQSS-----KLTKHKKIHTGEKPYTCE--ECGKAFNQSSNLTKHKRIHTGEKP--YKCEECDKAFKWS 514
Cdd:COG5048  352 AKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                        410
                 ....*....|.
gi 371873730 515 SVLTKHKIIHT 525
Cdd:COG5048  432 YNLIPHKKIHT 442
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
164-525 5.35e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 5.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 164 KPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKC--EECGKTFNRFSTLTTHKIIHTGEKPYKC-KECGKAFNRSSTLTTH 240
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 241 RKIHTGEKPYKCEECGKAFKQSSNLT--THKIIHTGEKPYK-CKKCGKAFNQSAHL-------------------TTHEV 298
Cdd:COG5048  112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLhpplpanslskdpssnlslLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 299 IHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLT 378
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 379 EHKKIHTGE-------KPYECEKCGKAFNQSSNLTRHKKS--HTEE--KPYKCEE--CGKGFKWPSTLTIHKIIHTGEKP 445
Cdd:COG5048  272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 446 YKC--EECGKAFNQSS-----KLTKHKKIHTGEKPYTCE--ECGKAFNQSSNLTKHKRIHTGEKP--YKCEECDKAFKWS 514
Cdd:COG5048  352 AKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                        410
                 ....*....|.
gi 371873730 515 SVLTKHKIIHT 525
Cdd:COG5048  432 YNLIPHKKIHT 442
zf-H2C2_2 pfam13465
Zinc-finger double domain;
488-512 4.46e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 4.46e-04
                          10        20
                  ....*....|....*....|....*
gi 371873730  488 NLTKHKRIHTGEKPYKCEECDKAFK 512
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
164-525 5.35e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 5.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 164 KPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKC--EECGKTFNRFSTLTTHKIIHTGEKPYKC-KECGKAFNRSSTLTTH 240
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 241 RKIHTGEKPYKCEECGKAFKQSSNLT--THKIIHTGEKPYK-CKKCGKAFNQSAHL-------------------TTHEV 298
Cdd:COG5048  112 SSSSNSNDNNLLSSHSLPPSSRDPQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLhpplpanslskdpssnlslLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 299 IHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLT 378
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 379 EHKKIHTGE-------KPYECEKCGKAFNQSSNLTRHKKS--HTEE--KPYKCEE--CGKGFKWPSTLTIHKIIHTGEKP 445
Cdd:COG5048  272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 446 YKC--EECGKAFNQSS-----KLTKHKKIHTGEKPYTCE--ECGKAFNQSSNLTKHKRIHTGEKP--YKCEECDKAFKWS 514
Cdd:COG5048  352 AKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                        410
                 ....*....|.
gi 371873730 515 SVLTKHKIIHT 525
Cdd:COG5048  432 YNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
176-504 4.91e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.18  E-value: 4.91e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 176 NQSSNLIKHKKIHTGE----KPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKC--KECGKAFNRSSTLTTHRKIHTGEKP 249
Cdd:COG5048   12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 250 YkcEECGKAFKQSSNLTTHKIIHTGEKPYKCKKC-GKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTHKIIH 328
Cdd:COG5048   92 D--LNSKSLPLSNSKASSSSLSSSSSNSNDNNLLsSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHP 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 329 TGEKPYKCKEcgkAFKHSSTLTKHKIIHTGEKPYKCKECEKaFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRH 408
Cdd:COG5048  170 PLPANSLSKD---PSSNLSLLISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSP 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 409 KKSHTEEKPYKCEECGKGFKWPSTLTIHKIIHTGE-------KPYKCEECGKAFNQSSKLTKHK--KIHTGE--KPYTCE 477
Cdd:COG5048  246 SSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCP 325

                        330       340
                 ....*....|....*....|....*....
gi 371873730 478 E--CGKAFNQSSNLTKHKRIHTGEKPYKC 504
Cdd:COG5048  326 YslCGKLFSRNDALKRHILLHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
171-425 2.30e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.79  E-value: 2.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 171 CGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTfNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPY 250
Cdd:COG5048  177 SKDPSSNLSLLISSNVSTSIPSSSENSPLSSS-YSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSS 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 251 KCEECGKAFKQSSNLTTHKIIHTGE-------KPYKCKKCGKAFNQSAHLTTH--EVIHTGE--KPYKC--EKCGKAFNH 317
Cdd:COG5048  256 SASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCpySLCGKLFSR 335

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 318 FSHLTTHKIIHTGEKPYKCKECGKAFKHS--------STLTKHKIIHTGEKPYKC-KECEKAFNQSSKLTEHKKIHTGEK 388
Cdd:COG5048  336 NDALKRHILLHTSISPAKEKLLNSSSKFSpllnneppQSLQQYKDLKNDKKSETLsNSCIRNFKRDSNLSLHIITHLSFR 415

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 371873730 389 PYECE--KCGKAFNQSSNLTRHKKSHTEEKPYKCEECGK 425
Cdd:COG5048  416 PYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
80-487 3.70e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 3.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730  80 KIFQCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTK--CGKSFGMISCLTEHSRIHT-RVNFYKCEECGKAFNWSStltKH 156
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHnNPSDLNSKSLPLSNSKAS---SS 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 157 KRIHTGEKPYKCE-ECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKEcgkAFNRSS 235
Cdd:COG5048  109 SLSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKD---PSSNLS 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 236 TLTTHRKIHTGEKPYKCEECGKA------------FKQSSNLTTHKIIHTGEKPYK---------------CKKCGKAFN 288
Cdd:COG5048  186 LLISSNVSTSIPSSSENSPLSSSysipssssdqnlENSSSSLPLTTNSQLSPKSLLsqspsslsssdssssASESPRSSL 265

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 289 QSAHLTTHEVIHTGE-------KPYKCEKCGKAFNHFSHLTTHK--IIHTGE--KPYKCKE--CGKAFKHSSTLTKHKII 355
Cdd:COG5048  266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 356 HTGEKPYKCK--ECEKAFNQSS-----KLTEHKKIHTGEKPYECE--KCGKAFNQSSNLTRHKKSHTEEKPYKCeecgkg 426
Cdd:COG5048  346 HTSISPAKEKllNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNC------ 419

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 371873730 427 fkwpstltihkiihtgekpyKCEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKAFNQSS 487
Cdd:COG5048  420 --------------------KNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
248-411 7.99e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.70  E-value: 7.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 248 KPYKCEECGKAFKQSSNLTTHK--IIHTGE--KPYKCKK--CGKAFNQSAHLTTHEVIHTGEKPYKC--EKCGKAFNHFS 319
Cdd:COG5048  288 LPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLL 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 320 ----HLTTHKIIHTGEKPYKC---KECGKAFKHSSTLTKHKIIHTGEKPY--KCKECEKAFNQSSKLTEHKKIHTGEKPY 390
Cdd:COG5048  368 nnepPQSLQQYKDLKNDKKSEtlsNSCIRNFKRDSNLSLHIITHLSFRPYncKNPPCSKSFNRHYNLIPHKKIHTNHAPL 447

                        170       180
                 ....*....|....*....|.
gi 371873730 391 ECEKCGKaFNQSSNLTRHKKS 411
Cdd:COG5048  448 LCSILKS-FRRDLDLSNHGKD 467
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 162-242 2.41e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.55  E-value: 2.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 162 GEKPYKCE--ECGKAFnQSSNLIKHKKIHTGEKPYKCEECGKTfnrfstltTHKIIHTGEKPYKCKECGKAFNRSSTLTT 239
Cdd:COG5189  346 DGKPYKCPveGCNKKY-KNQNGLKYHMLHGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ...
gi 371873730 240 HRK 242
Cdd:COG5189  417 HRK 419
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 442-521 2.65e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.55  E-value: 2.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 442 GEKPYKCE--ECGKAFNQSSKLTKHKKiHTGEKPYTCEecgkafnqSSNLTKHKRIHTGEKPYKCEECDKAFKWSSVLTK 519
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHE--------NPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 371873730 520 HK 521
Cdd:COG5189  417 HR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 293-413 3.47e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 3.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 293 LTTHEVIHTGEKPYKCEKCGKAFNHFSHLT----THKIIHTGEKPYKCK--ECGKAFKHSSTLTKHKiihtgekpyKCKE 366
Cdd:COG5189  305 ISTGEMIDVRKLPCTNSSSNGKLAHGGERNidtpSRMLKVKDGKPYKCPveGCNKKYKNQNGLKYHM---------LHGH 375

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 371873730 367 CEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHT 413
Cdd:COG5189  376 QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHRKHSH 422
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 386-466 3.86e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 3.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 386 GEKPYECE--KCGKAFNQSSNLTRHKKsHTEEKPYKCEEcgkgfkwPSTLTiHKIIHTGEKPYKCEECGKAFNQSSKLTK 463
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHEN-------PSPEK-MNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ...
gi 371873730 464 HKK 466
Cdd:COG5189  417 HRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
488-512 4.46e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 4.46e-04
                          10        20
                  ....*....|....*....|....*
gi 371873730  488 NLTKHKRIHTGEKPYKCEECDKAFK 512
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
153-177 1.01e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.01e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  153 LTKHKRIHTGEKPYKCEECGKAFNQ 177
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
180-205 1.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.11e-03
                          10        20
                  ....*....|....*....|....*.
gi 371873730  180 NLIKHKKIHTGEKPYKCEECGKTFNR 205
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
320-345 1.76e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.76e-03
                          10        20
                  ....*....|....*....|....*.
gi 371873730  320 HLTTHKIIHTGEKPYKCKECGKAFKH 345
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 190-269 1.88e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 1.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 371873730 190 GEKPYKCE--ECGKTFNRFSTLTTHKiihtgekpyKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTT 267
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 371873730 268 HK 269
Cdd:COG5189  417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
264-289 2.94e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 2.94e-03
                          10        20
                  ....*....|....*....|....*.
gi 371873730  264 NLTTHKIIHTGEKPYKCKKCGKAFNQ 289
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
237-261 3.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.11e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  237 LTTHRKIHTGEKPYKCEECGKAFKQ 261
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
404-428 3.37e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.37e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  404 NLTRHKKSHTEEKPYKCEECGKGFK 428
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
461-485 3.64e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.64e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  461 LTKHKKIHTGEKPYTCEECGKAFNQ 485
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
377-401 4.06e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 4.06e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  377 LTEHKKIHTGEKPYECEKCGKAFNQ 401
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
209-233 5.24e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 5.24e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  209 LTTHKIIHTGEKPYKCKECGKAFNR 233
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
349-373 5.61e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 5.61e-03
                          10        20
                  ....*....|....*....|....*
gi 371873730  349 LTKHKIIHTGEKPYKCKECEKAFNQ 373
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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