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Conserved domains on  [gi|731184192|ref|NP_001244942|]
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NADPH:adrenodoxin oxidoreductase, mitochondrial isoform 4 [Homo sapiens]

Protein Classification

ferredoxin--NADP reductase domain-containing protein( domain architecture ID 1000996)

ferredoxin--NADP reductase domain-containing protein may serve as an electron transfer protein and supply electrons to P450 systems

CATH:  3.40.50.720|3.50.50.60
EC:  1.18.1.-
Gene Ontology:  GO:0004324|GO:0050661|GO:0071949
PubMed:  10998235
SCOP:  4000129

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02852 super family cl30539
ferredoxin-NADP+ reductase
 71-518 0e+00

ferredoxin-NADP+ reductase


The actual alignment was detected with superfamily member PLN02852:

Pssm-ID: 357415  Cd Length: 491  Bit Score: 547.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  71 QICVVGSGPAGFYTAQHLLK-HPQAHVDIYEKQPVPFGLVRFGVAPDHPEVKNVINTFTQTAHSGRCAFWGNVEVGRDVT 149
Cdd:PLN02852  28 HVCVVGSGPAGFYTADKLLKaHDGARVDIIERLPTPFGLVRSGVAPDHPETKNVTNQFSRVATDDRVSFFGNVTLGRDVS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 150 VPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQELEPDL-SCDTAVILGQGNVALDVARILLT 228
Cdd:PLN02852 108 LSELRDLYHVVVLAYGAESDRRLGIPGEDLPGVLSAREFVWWYNGHPDCVHLPPDLkSSDTAVVLGQGNVALDCARILLR 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 229 PPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLPGARPILDPVDFLGLQDKIKEV--PRPRKR 306
Cdd:PLN02852 188 PTDELASTDIAEHALEALRGSSVRKVYLVGRRGPVQAACTAKELRELLGLKNVRVRIKEADLTLSPEDEEELkaSRPKRR 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 307 LTELLLRTATEKPGPAEAARQASAsrawgLRFFRSPQQVLPSPDG-RRAAGVRLAVTRLEGVDEATR--AVPTGDMEDLP 383
Cdd:PLN02852 268 VYELLSKAAAAGKCAPSGGQRELH-----FVFFRNPTRFLDSGDGnGHVAGVKLERTVLEGAAGSGKqvAVGTGEFEDLP 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 384 CGLVLSSIGYKSRPVDpSVPFDSKLGVIPNVEGRVM-------DVPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDL 456
Cdd:PLN02852 343 CGLVLKSIGYKSLPVD-GLPFDHKRGVVPNVHGRVLssasgadTEPGLYVVGWLKRGPTGIIGTNLTCAEETVASIAEDL 421

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 731184192 457 KAGLLP---SGPRPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLR 518
Cdd:PLN02852 422 EQGRLRgvaSPPKPGRDGLLELLESRGVRVVPFSGWEKIDSAEKEAGRARGKPREKITSIEEMLK 486
 
Name Accession Description Interval E-value
PLN02852 PLN02852
ferredoxin-NADP+ reductase
 71-518 0e+00

ferredoxin-NADP+ reductase


Pssm-ID: 215457  Cd Length: 491  Bit Score: 547.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  71 QICVVGSGPAGFYTAQHLLK-HPQAHVDIYEKQPVPFGLVRFGVAPDHPEVKNVINTFTQTAHSGRCAFWGNVEVGRDVT 149
Cdd:PLN02852  28 HVCVVGSGPAGFYTADKLLKaHDGARVDIIERLPTPFGLVRSGVAPDHPETKNVTNQFSRVATDDRVSFFGNVTLGRDVS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 150 VPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQELEPDL-SCDTAVILGQGNVALDVARILLT 228
Cdd:PLN02852 108 LSELRDLYHVVVLAYGAESDRRLGIPGEDLPGVLSAREFVWWYNGHPDCVHLPPDLkSSDTAVVLGQGNVALDCARILLR 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 229 PPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLPGARPILDPVDFLGLQDKIKEV--PRPRKR 306
Cdd:PLN02852 188 PTDELASTDIAEHALEALRGSSVRKVYLVGRRGPVQAACTAKELRELLGLKNVRVRIKEADLTLSPEDEEELkaSRPKRR 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 307 LTELLLRTATEKPGPAEAARQASAsrawgLRFFRSPQQVLPSPDG-RRAAGVRLAVTRLEGVDEATR--AVPTGDMEDLP 383
Cdd:PLN02852 268 VYELLSKAAAAGKCAPSGGQRELH-----FVFFRNPTRFLDSGDGnGHVAGVKLERTVLEGAAGSGKqvAVGTGEFEDLP 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 384 CGLVLSSIGYKSRPVDpSVPFDSKLGVIPNVEGRVM-------DVPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDL 456
Cdd:PLN02852 343 CGLVLKSIGYKSLPVD-GLPFDHKRGVVPNVHGRVLssasgadTEPGLYVVGWLKRGPTGIIGTNLTCAEETVASIAEDL 421

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 731184192 457 KAGLLP---SGPRPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLR 518
Cdd:PLN02852 422 EQGRLRgvaSPPKPGRDGLLELLESRGVRVVPFSGWEKIDSAEKEAGRARGKPREKITSIEEMLK 486
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 72-438 2.88e-37

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 142.58  E-value: 2.88e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  72 ICVVGSGPAGFYTAQHLLKhpQAH-VDIYEKQPVPFGLVRFGVaPDHPEVKNVIN-----------TFtqtahsgRCafw 139
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLAR--AGHeVTVFEALDKPGGLLRYGI-PEFRLPKDVLDreieliealgvEF-------RT--- 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 140 gNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGlpENQELEPDLSCDTAVILGQGNVA 219
Cdd:COG0493  191 -NVEVGKDITLDELLEEFDAVFLATGAGKPRDLGIPGEDLKGVHSAMDFLTAVNL--GEAPDTILAVGKRVVVIGGGNTA 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 220 LDVARILLtppehleRtditkaaLGvlrqsrVKTVWLVGRRGPLQVAFTIKELREmiqlpgarpildpvdflGLQDKIKe 299
Cdd:COG0493  268 MDCARTAL-------R-------LG------AESVTIVYRRTREEMPASKEEVEE-----------------ALEEGVE- 309

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 300 vprprkrltelllrtatekpgpaeaarqasasrawgLRFFRSPQQVLPSPDGrRAAGVRLAVTRLEGVDEATRAVP---T 376
Cdd:COG0493  310 ------------------------------------FLFLVAPVEIIGDENG-RVTGLECVRMELGEPDESGRRRPvpiE 352

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 731184192 377 GDMEDLPCGLVLSSIGYKSRPV----DPSVPFDSKLGVIPNVEGRVMDVPGLYCSGWVKRGPTGVI 438
Cdd:COG0493  353 GSEFTLPADLVILAIGQTPDPSgleeELGLELDKRGTIVVDEETYQTSLPGVFAGGDAVRGPSLVV 418
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 70-255 7.92e-06

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 47.70  E-value: 7.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192   70 PQICVVGSGPAGFYTAQHLLKHpQAHVDIYEK-------QPVPFGLVRFGVAPDHPE---------VKNVINTFTQ--TA 131
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQL-GGKVTLIEDegtcpygGCVLSKALLGAAEAPEIAslwadlykrKEEVVKKLNNgiEV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  132 HSGRCAF-----WGNVEVGRDVTVPELQEAYHAVVLSYGAEDhRALEIPGEELPGVCSARAfvgwyngLPENQELEPDLS 206
Cdd:pfam07992  80 LLGTEVVsidpgAKKVVLEELVDGDGETITYDRLVIATGARP-RLPPIPGVELNVGFLVRT-------LDSAEALRLKLL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 731184192  207 CDTAVILGQGNVALDVARILL------TPPEHLER------TDITKAALGVLRQSRVKTVW 255
Cdd:pfam07992 152 PKRVVVVGGGYIGVELAAALAklgkevTLIEALDRllrafdEEISAALEKALEKNGVEVRL 212
 
Name Accession Description Interval E-value
PLN02852 PLN02852
ferredoxin-NADP+ reductase
 71-518 0e+00

ferredoxin-NADP+ reductase


Pssm-ID: 215457  Cd Length: 491  Bit Score: 547.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  71 QICVVGSGPAGFYTAQHLLK-HPQAHVDIYEKQPVPFGLVRFGVAPDHPEVKNVINTFTQTAHSGRCAFWGNVEVGRDVT 149
Cdd:PLN02852  28 HVCVVGSGPAGFYTADKLLKaHDGARVDIIERLPTPFGLVRSGVAPDHPETKNVTNQFSRVATDDRVSFFGNVTLGRDVS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 150 VPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQELEPDL-SCDTAVILGQGNVALDVARILLT 228
Cdd:PLN02852 108 LSELRDLYHVVVLAYGAESDRRLGIPGEDLPGVLSAREFVWWYNGHPDCVHLPPDLkSSDTAVVLGQGNVALDCARILLR 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 229 PPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLPGARPILDPVDFLGLQDKIKEV--PRPRKR 306
Cdd:PLN02852 188 PTDELASTDIAEHALEALRGSSVRKVYLVGRRGPVQAACTAKELRELLGLKNVRVRIKEADLTLSPEDEEELkaSRPKRR 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 307 LTELLLRTATEKPGPAEAARQASAsrawgLRFFRSPQQVLPSPDG-RRAAGVRLAVTRLEGVDEATR--AVPTGDMEDLP 383
Cdd:PLN02852 268 VYELLSKAAAAGKCAPSGGQRELH-----FVFFRNPTRFLDSGDGnGHVAGVKLERTVLEGAAGSGKqvAVGTGEFEDLP 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 384 CGLVLSSIGYKSRPVDpSVPFDSKLGVIPNVEGRVM-------DVPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDL 456
Cdd:PLN02852 343 CGLVLKSIGYKSLPVD-GLPFDHKRGVVPNVHGRVLssasgadTEPGLYVVGWLKRGPTGIIGTNLTCAEETVASIAEDL 421

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 731184192 457 KAGLLP---SGPRPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLR 518
Cdd:PLN02852 422 EQGRLRgvaSPPKPGRDGLLELLESRGVRVVPFSGWEKIDSAEKEAGRARGKPREKITSIEEMLK 486
PTZ00188 PTZ00188
adrenodoxin reductase; Provisional
 35-520 1.65e-50

adrenodoxin reductase; Provisional


Pssm-ID: 240308  Cd Length: 506  Bit Score: 180.46  E-value: 1.65e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  35 RDPANAKALRNKRRRMQVRVKLGKFQLLLDIQEKTP-QICVVGSGPAGFYTAQHLLKHPQAHVDIYEKQPVPFGLVRFGV 113
Cdd:PTZ00188   4 RNFLCSPAQRTLARGWHLGGKLPFTGKCFFTNEAKPfKVGIIGAGPSALYCCKHLLKHERVKVDIFEKLPNPYGLIRYGV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 114 APDHPEVKNVINTFTQTAHSGRCAFWGNVEVGRDVTVPELQEAYHAVVLSYGA---------EDHRALEIPGEELP---- 180
Cdd:PTZ00188  84 APDHIHVKNTYKTFDPVFLSPNYRFFGNVHVGVDLKMEELRNHYNCVIFCCGAsevsipigqQDEDKAVSGGETNPrkqn 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 181 GVCSARAFVGWYNGLPEnqelepDLSC-------------DTAVILGQGNVALDVARILLTPPEHLERTDITKAALGVLR 247
Cdd:PTZ00188 164 GIFHARDLIYFYNNMYN------DVRCkavdnylnsfenfTTSIIIGNGNVSLDIARILIKSPDDLSKTDISSDYLKVIK 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 248 QSRVKTVWLVGRRGPLQVAFTIKELREMIQLPGARPILDPVDFlGLQDKIK---EVPRPRKRLTELLLRTATEKPGPAEA 324
Cdd:PTZ00188 238 RHNIKHIYIVGRRGFWQSSFTNAELRELISLENTKVILSKKNY-DLCCHLKsdeENTNMKKRQHEIFQKMVKNYEEVEKN 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 325 ARQASASRAWGLRFFRSPQQVLPspdgrraagvrlavtrlegVDEATRAVPTGDMEDLPcgLVLSSIGYKSRPVDPSVPF 404
Cdd:PTZ00188 317 KEFYKTYKIIEFIFYFEIRQIRP-------------------IDGAMKNVELELNKNVP--MSFSSFKENKVLVTPLVIF 375

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 405 DS---KLGVIPNVEGRVMDVP---------GLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDL-KAGLLPSGPrpgyaa 471
Cdd:PTZ00188 376 ATgfkKSNFAENLYNQSVQMFkedigqhkfAIFKAGWFDKGPKGNIASQILNSKNSTHLVLNFLqKVDIFFDND------ 449

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 731184192 472 IQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLRLL 520
Cdd:PTZ00188 450 ISSLLKEKQIPYVSFDDWTYLHQLEKQMGAQQNKIAQKFSQTGEVLRIL 498
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 72-438 2.88e-37

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 142.58  E-value: 2.88e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  72 ICVVGSGPAGFYTAQHLLKhpQAH-VDIYEKQPVPFGLVRFGVaPDHPEVKNVIN-----------TFtqtahsgRCafw 139
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLAR--AGHeVTVFEALDKPGGLLRYGI-PEFRLPKDVLDreieliealgvEF-------RT--- 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 140 gNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGlpENQELEPDLSCDTAVILGQGNVA 219
Cdd:COG0493  191 -NVEVGKDITLDELLEEFDAVFLATGAGKPRDLGIPGEDLKGVHSAMDFLTAVNL--GEAPDTILAVGKRVVVIGGGNTA 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 220 LDVARILLtppehleRtditkaaLGvlrqsrVKTVWLVGRRGPLQVAFTIKELREmiqlpgarpildpvdflGLQDKIKe 299
Cdd:COG0493  268 MDCARTAL-------R-------LG------AESVTIVYRRTREEMPASKEEVEE-----------------ALEEGVE- 309

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 300 vprprkrltelllrtatekpgpaeaarqasasrawgLRFFRSPQQVLPSPDGrRAAGVRLAVTRLEGVDEATRAVP---T 376
Cdd:COG0493  310 ------------------------------------FLFLVAPVEIIGDENG-RVTGLECVRMELGEPDESGRRRPvpiE 352

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 731184192 377 GDMEDLPCGLVLSSIGYKSRPV----DPSVPFDSKLGVIPNVEGRVMDVPGLYCSGWVKRGPTGVI 438
Cdd:COG0493  353 GSEFTLPADLVILAIGQTPDPSgleeELGLELDKRGTIVVDEETYQTSLPGVFAGGDAVRGPSLVV 418
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 72-224 8.88e-20

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 91.78  E-value: 8.88e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  72 ICVVGSGPAGFyTAQHLLKHpQAH-VDIYEKQPVPFGLVRFGVapdhPE---VKNVINTFTQTAHSGRCAFWGNVEVGRD 147
Cdd:PRK11749 143 VAVIGAGPAGL-TAAHRLAR-KGYdVTIFEARDKAGGLLRYGI----PEfrlPKDIVDREVERLLKLGVEIRTNTEVGRD 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 148 VTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFvgwyngLPE-NQ--ELEPDLSCDTAVILGQGNVALDVAR 224
Cdd:PRK11749 217 ITLDELRAGYDAVFIGTGAGLPRFLGIPGENLGGVYSAVDF------LTRvNQavADYDLPVGKRVVVIGGGNTAMDAAR 290
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 72-224 1.50e-18

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 88.78  E-value: 1.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  72 ICVVGSGPAGFYTAQHL--LKHpqaHVDIYEKQPVPFGLVRFGVaPDH--P------EVKNVINTFTQTahsgRCafwgN 141
Cdd:PRK12771 140 VAVIGGGPAGLSAAYHLrrMGH---AVTIFEAGPKLGGMMRYGI-PAYrlPrevldaEIQRILDLGVEV----RL----G 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 142 VEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNglpenqELEPDLSCDTAVILGQGNVALD 221
Cdd:PRK12771 208 VRVGEDITLEQLEGEFDAVFVAIGAQLGKRLPIPGEDAAGVLDAVDFLRAVG------EGEPPFLGKRVVVIGGGNTAMD 281


                 ...
gi 731184192 222 VAR 224
Cdd:PRK12771 282 AAR 284
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 30-224 1.06e-16

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 83.15  E-value: 1.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  30 GSDEVRDPANAKALRNKRRRM-QVRVKLGKFQLLLDIQEKTPQICVVGSGPAGFYTAQhLLKHPQAHVDIYEKQPVPFGL 108
Cdd:PRK12809 270 GACTLKDHSGAVSIGNLERYItDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCAD-ILARAGVQVDVFDRHPEIGGM 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 109 VRFGVAPDHPEvKNVINTFTQTAHSGRCAFWGNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAF 188
Cdd:PRK12809 349 LTFGIPPFKLD-KTVLSQRREIFTAMGIDFHLNCEIGRDITFSDLTSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPF 427

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 731184192 189 VGWYN----GLPENQELE-PDLSCDTAVILGQGNVALDVAR 224
Cdd:PRK12809 428 LTAHTrqlmGLPESEEYPlTDVEGKRVVVLGGGDTTMDCLR 468
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 74-182 4.31e-16

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 80.59  E-value: 4.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  74 VVGSGPAGFYTAQHLLK--HpQAHVdiYEKQPVPFGLVRFGVaPDHPEVKNVIN-----------TFtqtahsgRCafwg 140
Cdd:PRK12810 148 VVGSGPAGLAAADQLARagH-KVTV--FERADRIGGLLRYGI-PDFKLEKEVIDrrielmeaegiEF-------RT---- 212

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 731184192 141 NVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGV 182
Cdd:PRK12810 213 NVEVGKDITAEELLAEYDAVFLGTGAYKPRDLGIPGRDLDGV 254
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 65-227 2.93e-15

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 78.62  E-value: 2.93e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  65 IQEKT-PQICVVGSGPAGFYTAQHLLKhpQAH-VDIYEKQPVPFGLVRFGVaPDH--PEvkNVINTFTQTAHSGRCAFWG 140
Cdd:PRK12814 188 RAPKSgKKVAIIGAGPAGLTAAYYLLR--KGHdVTIFDANEQAGGMMRYGI-PRFrlPE--SVIDADIAPLRAMGAEFRF 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 141 NVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVgwyNGLPENQELEPDLScdtAVILGQGNVAL 220
Cdd:PRK12814 263 NTVFGRDITLEELQKEFDAVLLAVGAQKASKMGIPGEELPGVISGIDFL---RNVALGTALHPGKK---VVVIGGGNTAI 336


                 ....*..
gi 731184192 221 DVARILL 227
Cdd:PRK12814 337 DAARTAL 343
PRK13984 PRK13984
putative oxidoreductase; Provisional
 42-224 5.81e-14

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 74.42  E-value: 5.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  42 ALRNKRRRMQVRVKLGKFQLLLD--IQEKTPQICVVGSGPAGFyTAQHLLKHPQAHVDIYEKQPVPFGLVRFGVA----P 115
Cdd:PRK13984 254 AIRWLKRYIVDNVPVEKYSEILDdePEKKNKKVAIVGSGPAGL-SAAYFLATMGYEVTVYESLSKPGGVMRYGIPsyrlP 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 116 DHPEVK--NVINTFTQTAHSgrcafwgNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSArafvgwyn 193
Cdd:PRK13984 333 DEALDKdiAFIEALGVKIHL-------NTRVGKDIPLEELREKHDAVFLSTGFTLGRSTRIPGTDHPDVIQA-------- 397

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 731184192 194 gLPENQELEPDLSCD--------TAVILGQGNVALDVAR 224
Cdd:PRK13984 398 -LPLLREIRDYLRGEgpkpkiprSLVVIGGGNVAMDIAR 435
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 58-309 8.32e-14

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 72.71  E-value: 8.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  58 KFQLLL-DIQEKTP-QICVVGSGPAGFYTAQHLLkhPQAH-VDIYEKQPVPFGLVRFGVAPDHPEVKNV----------- 123
Cdd:PRK12770   5 KFAFMCkEKPPPTGkKVAIIGAGPAGLAAAGYLA--CLGYeVHVYDKLPEPGGLMLFGIPEFRIPIERVregvkeleeag 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 124 INTFTQT---AHSGRCAFWGNVEVGRDVTVPELQEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGW-----YNGL 195
Cdd:PRK12770  83 VVFHTRTkvcCGEPLHEEEGDEFVERIVSLEELVKKYDAVLIATGTWKSRKLGIPGEDLPGVYSALEYLFRiraakLGYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 196 PenQELEPDLSCDTAVILGQGNVALDVArilltppehlertdITKAALGvlrqsrVKTVWLVGRRgPLQVA----FTIKE 271
Cdd:PRK12770 163 P--WEKVPPVEGKKVVVVGAGLTAVDAA--------------LEAVLLG------AEKVYLAYRR-TINEApagkYEIER 219

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 731184192 272 LREMiqlpGA--RPILDPVDFLGlQDKIKEVPRPRKRLTE 309
Cdd:PRK12770 220 LIAR----GVefLELVTPVRIIG-EGRVEGVELAKMRLGE 254
PRK12775 PRK12775
putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin ...
 64-438 1.22e-13

putative trifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta/ferritin domain-containing protein; Provisional


Pssm-ID: 183738 [Multi-domain]  Cd Length: 1006  Bit Score: 73.82  E-value: 1.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192   64 DIQEKTPQICVVGSGPAGFYTAQHLLKHpQAHVDIYEKQPVPFGLVRFGVaPDHPEVKNVINTFTQTAHSGRCAFWGNVE 143
Cdd:PRK12775  425 RFSKKLGKVAICGSGPAGLAAAADLVKY-GVDVTVYEALHVVGGVLQYGI-PSFRLPRDIIDREVQRLVDIGVKIETNKV 502

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  144 VGRDVTVPEL--QEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQ--ELEPDLSCDTAVI-LGQGNV 218
Cdd:PRK12775  503 IGKTFTVPQLmnDKGFDAVFLGVGAGAPTFLGIPGEFAGQVYSANEFLTRVNLMGGDKfpFLDTPISLGKSVVvIGAGNT 582

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  219 ALDVARilltppehlertditkaalgVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQlpgarpilDPVDFLglqdkik 298
Cdd:PRK12775  583 AMDCLR--------------------VAKRLGAPTVRCVYRRSEAEAPARIEEIRHAKE--------EGIDFF------- 627

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  299 evprprkrltelllrtatekpgpaeaarqasasrawglrFFRSPQQVLPSPDGrRAAGVRLAVTRLEGVDEATR--AVPT 376
Cdd:PRK12775  628 ---------------------------------------FLHSPVEIYVDAEG-SVRGMKVEEMELGEPDEKGRrkPMPT 667

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 731184192  377 GDMEDLPCGLVLSSIGYKSRPV----DPSVPFDsKLGVIPNVEGRVMD-----VPGLYCSGWVKRGPTGVI 438
Cdd:PRK12775  668 GEFKDLECDTVIYALGTKANPIitqsTPGLALN-KWGNIAADDGKLEStqstnLPGVFAGGDIVTGGATVI 737
PRK12831 PRK12831
putative oxidoreductase; Provisional
 71-227 2.09e-12

putative oxidoreductase; Provisional


Pssm-ID: 183780 [Multi-domain]  Cd Length: 464  Bit Score: 69.28  E-value: 2.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  71 QICVVGSGPAGFYTAQHLLKHpQAHVDIYEKQPVPFGLVRFGVA----PDHPEVKNVINTFTQTAhsgrCAFWGNVEVGR 146
Cdd:PRK12831 142 KVAVIGSGPAGLTCAGDLAKM-GYDVTIFEALHEPGGVLVYGIPefrlPKETVVKKEIENIKKLG----VKIETNVVVGK 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 147 DVTVPEL--QEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLpenQELEPDLscDTAVILGQ-------GN 217
Cdd:PRK12831 217 TVTIDELleEEGFDAVFIGSGAGLPKFMGIPGENLNGVFSANEFLTRVNLM---KAYKPEY--DTPIKVGKkvavvggGN 291

                        170
                 ....*....|
gi 731184192 218 VALDVARILL 227
Cdd:PRK12831 292 VAMDAARTAL 301
PRK12779 PRK12779
putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; ...
 70-224 1.21e-08

putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Provisional


Pssm-ID: 183740 [Multi-domain]  Cd Length: 944  Bit Score: 57.92  E-value: 1.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  70 PQICVVGSGPAGFYTAqHLLKHPQAHVDIYEKQPVPFGLVRFGVapdhPE-------VKNVINTFtqTAHSGRcaFWGNV 142
Cdd:PRK12779 307 PPIAVVGSGPSGLINA-YLLAVEGFPVTVFEAFHDLGGVLRYGI----PEfrlpnqlIDDVVEKI--KLLGGR--FVKNF 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 143 EVGRDVTVPEL-QEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAF---VGWYNGLPENQELE-PDLSCDTAVILGQGN 217
Cdd:PRK12779 378 VVGKTATLEDLkAAGFWKIFVGTGAGLPTFMNVPGEHLLGVMSANEFltrVNLMRGLDDDYETPlPEVKGKEVFVIGGGN 457


                 ....*..
gi 731184192 218 VALDVAR 224
Cdd:PRK12779 458 TAMDAAR 464
PRK12778 PRK12778
bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate ...
 71-438 1.51e-08

bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate synthase;


Pssm-ID: 237200 [Multi-domain]  Cd Length: 752  Bit Score: 57.44  E-value: 1.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  71 QICVVGSGPAGFYTAQHLLKhpQAH-VDIYEKQPVPFGLVRFGVaPDHPEVKNVINTFTQTAHSGRCAFWGNVEVGRDVT 149
Cdd:PRK12778 433 KVAVIGSGPAGLSFAGDLAK--RGYdVTVFEALHEIGGVLKYGI-PEFRLPKKIVDVEIENLKKLGVKFETDVIVGKTIT 509

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 150 VPEL-QEAYHAVVLSYGAEDHRALEIPGEELPGVCSARAFVGWYNGLPENQEL--EPDLSCDTAVILGQGNVALDVARil 226
Cdd:PRK12778 510 IEELeEEGFKGIFIASGAGLPNFMNIPGENSNGVMSSNEYLTRVNLMDAASPDsdTPIKFGKKVAVVGGGNTAMDSAR-- 587

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 227 ltppehlertdiTKAALGvlrqsrVKTVWLVGRRGPlqvaftikelremiqlpgarpildpvdflglqdkiKEVPrprKR 306
Cdd:PRK12778 588 ------------TAKRLG------AERVTIVYRRSE-----------------------------------EEMP---AR 611

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 307 LTEllLRTATEKpgpaeaarqasasrawGLRF--FRSPQQVLPSPDGrRAAGVRLAVTRLEGVDEATRAVP---TGDMED 381
Cdd:PRK12778 612 LEE--VKHAKEE----------------GIEFltLHNPIEYLADEKG-WVKQVVLQKMELGEPDASGRRRPvaiPGSTFT 672

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192 382 LPCGLVLSSIGYKSRPVDPSVPFDSKL---GVIPNVEGRVMDVPGLYCSGWVKRGPTGVI 438
Cdd:PRK12778 673 VDVDLVIVSVGVSPNPLVPSSIPGLELnrkGTIVVDEEMQSSIPGIYAGGDIVRGGATVI 732
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 70-255 7.92e-06

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 47.70  E-value: 7.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192   70 PQICVVGSGPAGFYTAQHLLKHpQAHVDIYEK-------QPVPFGLVRFGVAPDHPE---------VKNVINTFTQ--TA 131
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQL-GGKVTLIEDegtcpygGCVLSKALLGAAEAPEIAslwadlykrKEEVVKKLNNgiEV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731184192  132 HSGRCAF-----WGNVEVGRDVTVPELQEAYHAVVLSYGAEDhRALEIPGEELPGVCSARAfvgwyngLPENQELEPDLS 206
Cdd:pfam07992  80 LLGTEVVsidpgAKKVVLEELVDGDGETITYDRLVIATGARP-RLPPIPGVELNVGFLVRT-------LDSAEALRLKLL 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 731184192  207 CDTAVILGQGNVALDVARILL------TPPEHLER------TDITKAALGVLRQSRVKTVW 255
Cdd:pfam07992 152 PKRVVVVGGGYIGVELAAALAklgkevTLIEALDRllrafdEEISAALEKALEKNGVEVRL 212
PRK07233 PRK07233
hypothetical protein; Provisional
 72-108 5.81e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 39.10  E-value: 5.81e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 731184192  72 ICVVGSGPAGFYTAQHLLKHPQaHVDIYEKQPVPFGL 108
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGH-EVTVFEADDQLGGL 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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