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Conserved domains on  [gi|167466175|ref|NP_001247|]
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cell division cycle protein 27 homolog isoform 2 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 12124078)

tetratricopeptide repeat (TPR) protein with an ANAPC3 (anaphase-promoting complex, subunit 3) domain, such as human cell division cycle protein 27 homolog and Dictyostelium discoideum anaphase-promoting complex/cyclosome (APC/C) subunit 3

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  16896351|21153002|10517866|30708253
SCOP:  4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
561-731 3.47e-40

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 148.62  E-value: 3.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|.
gi 167466175 721 SALQELEELKQ 731
Cdd:COG0457  162 EALELLEKLEA 172
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 17-92 6.62e-22

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


:

Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 90.39  E-value: 6.62e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 167466175   17 NHYAYRDAVFLAERLY-AEVHSEEALFLLATCYYRSGKAYKAYRLLKGH--SCTTPQCKYLLAKCCVDLSKLAEGEQIL 92
Cdd:pfam12895   1 DQHQYKNAIFLAERLLaAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAklNGSSLGCRYLFAQCLLKLKKYDEALDAL 79
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 448-671 3.64e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.57  E-value: 3.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 448 QIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSHLpshhyntgwvlcqiGRAYFELSEYMQAERIFSEVRR 527
Cdd:COG3914   41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA--------------ALLLQALGRYEEALALYRRALA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 528 IENYRVEGMEIYSTTLWHLQKDV-ALSVLSKdLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL 606
Cdd:COG3914  107 LNPDNAEALFNLGNLLLALGRLEeALAALRR-ALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167466175 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
Cdd:COG3914  186 LGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSEL 250
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
665-804 1.04e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 59.54  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 665 NPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 745 KVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQ 804
Cdd:COG4785  149 IALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALALLLEDWATAYLLQ 208
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
561-731 3.47e-40

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 148.62  E-value: 3.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|.
gi 167466175 721 SALQELEELKQ 731
Cdd:COG0457  162 EALELLEKLEA 172
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 17-92 6.62e-22

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 90.39  E-value: 6.62e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 167466175   17 NHYAYRDAVFLAERLY-AEVHSEEALFLLATCYYRSGKAYKAYRLLKGH--SCTTPQCKYLLAKCCVDLSKLAEGEQIL 92
Cdd:pfam12895   1 DQHQYKNAIFLAERLLaAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAklNGSSLGCRYLFAQCLLKLKKYDEALDAL 79
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 580-812 2.01e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 80.90  E-value: 2.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  580 QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGL------------------ 641
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALatilieagefeeaekhad 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  642 ----------------GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705
Cdd:TIGR02917 252 allkkapnsplahylkALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQA 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  706 KFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLP 785
Cdd:TIGR02917 332 RRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQG 411

                         250       260
                  ....*....|....*....|....*..
gi 167466175  786 DDEEPITQEEQIMGTDesqeSSMTDAD 812
Cdd:TIGR02917 412 DPSEAIADLETAAQLD----PELGRAD 434
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 448-671 3.64e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.57  E-value: 3.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 448 QIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSHLpshhyntgwvlcqiGRAYFELSEYMQAERIFSEVRR 527
Cdd:COG3914   41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA--------------ALLLQALGRYEEALALYRRALA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 528 IENYRVEGMEIYSTTLWHLQKDV-ALSVLSKdLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL 606
Cdd:COG3914  107 LNPDNAEALFNLGNLLLALGRLEeALAALRR-ALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167466175 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
Cdd:COG3914  186 LGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSEL 250
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
665-804 1.04e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 59.54  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 665 NPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 745 KVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQ 804
Cdd:COG4785  149 IALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALALLLEDWATAYLLQ 208
TPR_1 pfam00515
Tetratricopeptide repeat;
635-667 5.66e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 49.34  E-value: 5.66e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 167466175  635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 582-697 9.01e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 54.56  E-value: 9.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 582 EHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH-YNAWYGLGMIYYKQEkfSLAemHFQK 660
Cdd:cd24142   15 NFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLSGGEE--ALQ--YYEK 90

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 167466175 661 ALDInpqssvLLCHIGVVQHALKKSEKALDTLNKAIV 697
Cdd:cd24142   91 GIEI------LEEELQALQAASAEAEEEAEELKRKLS 121
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 635-667 3.27e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 47.06  E-value: 3.27e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 167466175   635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 507-733 3.74e-06

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 50.19  E-value: 3.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 507 RAYFELSE-YMQ------AERIFSEVRRIENYRVEG----MEIY-STTLWhlQK--DVALSVLSKDLTDMDKNSPEAWCA 572
Cdd:PRK11788 108 LALQELGQdYLKaglldrAEELFLQLVDEGDFAEGAlqqlLEIYqQEKDW--QKaiDVAERLEKLGGDSLRVEIAHFYCE 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 573 AGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHynawygLGMI-------Y 645
Cdd:PRK11788 186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPEY------LSEVlpklmecY 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 646 YKQEKFSLAEMHFQKALDINPQSSVLLChigVVQHALKK--SEKALDTLNKAIvidPKNP-LCKFHR---ASVLFANEky 719
Cdd:PRK11788 260 QALGDEAEGLEFLRRALEEYPGADLLLA---LAQLLEEQegPEAAQALLREQL---RRHPsLRGFHRlldYHLAEAEE-- 331

                        250
                 ....*....|....
gi 167466175 720 KSALQELEELKQIV 733
Cdd:PRK11788 332 GRAKESLLLLRDLV 345
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 9-146 8.79e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.59  E-value: 8.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175   9 QAAIWQALNHYAyrDAVFLAER-LYAEVHSEEALFLLATCYYRSGK---AYKAYRLLKGHSCTTPQCKYLLAKCCVDLSK 84
Cdd:COG3914   84 AALLLQALGRYE--EALALYRRaLALNPDNAEALFNLGNLLLALGRleeALAALRRALALNPDFAEAYLNLGEALRRLGR 161

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 167466175  85 LAEGEQILSGGVfnkQKSHDDIVTefgdsacftLSLLGHVYCKTDRLAKGSECYQKSLSLNP 146
Cdd:COG3914  162 LEEAIAALRRAL---ELDPDNAEA---------LNNLGNALQDLGRLEEAIAAYRRALELDP 211
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
561-731 3.47e-40

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 148.62  E-value: 3.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|.
gi 167466175 721 SALQELEELKQ 731
Cdd:COG0457  162 EALELLEKLEA 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 570-769 1.48e-37

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 141.79  E-value: 1.48e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 570 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 649
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 167466175 730 KQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
Cdd:COG2956  171 LKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPD 210
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
594-760 4.52e-36

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 136.68  E-value: 4.52e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLC 673
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 674 HIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160


                 ....*..
gi 167466175 754 HLALMNF 760
Cdd:COG0457  161 EEALELL 167
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 547-768 4.92e-36

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 137.55  E-value: 4.92e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 547 QKDVALSVLsKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626
Cdd:COG2956   23 QPDKAIDLL-EEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCK 706
Cdd:COG2956  102 LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 167466175 707 FHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768
Cdd:COG2956  182 LLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 483-729 3.25e-31

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 123.69  E-value: 3.25e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGM----EIYsttlwHLQKDV--ALSVLS 556
Cdd:COG2956   26 KAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALlelaQDY-----LKAGLLdrAEELLE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 557 KdLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYN 636
Cdd:COG2956  101 K-LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLcKFHRASVLFAN 716
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-LLALADLLERK 258

                        250
                 ....*....|...
gi 167466175 717 EKYKSALQELEEL 729
Cdd:COG2956  259 EGLEAALALLERQ 271
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
497-729 1.54e-30

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 120.88  E-value: 1.54e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIenyrvegmeiysttlwhlqkdvalsvlskdltdmDKNSPEAWCAAGNC 576
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL----------------------------------DPDDAEALYNLGLA 51

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 577 FSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656
Cdd:COG0457   52 YLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIE 131

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167466175 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729
Cdd:COG0457  132 AYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALE 204
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
628-796 1.76e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 112.02  E-value: 1.76e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 708 HRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDD 787
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160


                 ....*....
gi 167466175 788 EEPITQEEQ 796
Cdd:COG0457  161 EEALELLEK 169
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 499-757 1.95e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 112.52  E-value: 1.95e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 499 GWVLcqIGRAYFELSEYMQAERIFSEVRRIENYRVEgmeIYST--TLWHLQKDV--ALSVLSKdLTDMDKNSPEAWCAAG 574
Cdd:COG2956   10 GWYF--KGLNYLLNGQPDKAIDLLEEALELDPETVE---AHLAlgNLYRRRGEYdrAIRIHQK-LLERDPDRAEALLELA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 575 NCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA 654
Cdd:COG2956   84 QDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 655 EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734
Cdd:COG2956  164 IEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243

                        250       260
                 ....*....|....*....|...
gi 167466175 735 kESLVYFLIGKVYKKLGQTHLAL 757
Cdd:COG2956  244 -SDDLLLALADLLERKEGLEAAL 265
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 568-702 1.92e-26

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 105.27  E-value: 1.92e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 167466175 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKN 702
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 580-732 5.37e-26

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 113.93  E-value: 5.37e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 580 QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQ 659
Cdd:COG3914   91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALR 170

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167466175 660 KALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQI 732
Cdd:COG3914  171 RALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 601-778 4.53e-25

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 105.58  E-value: 4.53e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQH 680
Cdd:COG2956    8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 681 ALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760
Cdd:COG2956   88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEAL 167

                        170
                 ....*....|....*...
gi 167466175 761 SWAMDLDPKGANNQIKEA 778
Cdd:COG2956  168 EKALKLDPDCARALLLLA 185
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 619-742 1.78e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 93.53  E-value: 1.78e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 167466175 699 DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFL 742
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 565-669 3.58e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 92.76  E-value: 3.58e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMI 644
Cdd:COG4235   15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                         90       100
                 ....*....|....*....|....*
gi 167466175 645 YYKQEKFSLAEMHFQKALDINPQSS 669
Cdd:COG4235   95 AFQQGDYAEAIAAWQKLLALLPADA 119
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 601-736 6.22e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 92.56  E-value: 6.22e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQH 680
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 167466175 681 ALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKE 736
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 17-92 6.62e-22

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 90.39  E-value: 6.62e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 167466175   17 NHYAYRDAVFLAERLY-AEVHSEEALFLLATCYYRSGKAYKAYRLLKGH--SCTTPQCKYLLAKCCVDLSKLAEGEQIL 92
Cdd:pfam12895   1 DQHQYKNAIFLAERLLaAEPESPEDAYLLAQCLFLNGQYKRAYELLRKAklNGSSLGCRYLFAQCLLKLKKYDEALDAL 79
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 557-668 6.92e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 92.18  E-value: 6.92e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYN 636
Cdd:COG4783   28 EKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107

                         90       100       110
                 ....*....|....*....|....*....|..
gi 167466175 637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668
Cdd:COG4783  108 AYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
546-724 9.06e-21

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 91.90  E-value: 9.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 546 LQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625
Cdd:COG4785   52 ALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFD 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS--SVLLCHIgvvQHALKKSEKALDTLNKAIvidPKNP 703
Cdd:COG4785  132 RALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDpeRALWLYL---AERKLDPEKALALLLEDW---ATAY 205

                        170       180
                 ....*....|....*....|.
gi 167466175 704 LCKFHRASvlfANEKYKSALQ 724
Cdd:COG4785  206 LLQGDTEE---ARELFKLALA 223
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 465-699 1.47e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 92.48  E-value: 1.47e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 465 LLREMGKGYLALCSYNckEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFsevrrienyrvegmeiysttlw 544
Cdd:COG2956   78 ALLELAQDYLKAGLLD--RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVL---------------------- 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 545 hlqkdvalsvlsKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624
Cdd:COG2956  134 ------------ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAAL 201

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167466175 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLcHIGVVQHALKKSEKALDTLNKAIVID 699
Cdd:COG2956  202 ERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-ALADLLERKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 637-769 1.69e-20

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 88.33  E-value: 1.69e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 167466175 717 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 586-703 2.29e-20

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 87.75  E-value: 2.29e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN 665
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 167466175 666 PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP 703
Cdd:COG4235   82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 475-675 8.95e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.29  E-value: 8.95e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 475 ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQK----DV 550
Cdd:COG3914   17 LLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQAlgryEE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 551 ALSVLSKDLtDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV 630
Cdd:COG3914   97 ALALYRRAL-ALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 167466175 631 NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
Cdd:COG3914  176 DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 591-743 1.91e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 93.13  E-value: 1.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 591 QRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV 670
Cdd:COG3914   68 AAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE 147

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167466175 671 LLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLI 743
Cdd:COG3914  148 AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
576-666 1.46e-18

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 81.37  E-value: 1.46e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 576 CFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAcFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|.
gi 167466175 656 MHFQKALDINP 666
Cdd:COG3063   80 AYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 572-666 1.78e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 83.09  E-value: 1.78e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651
Cdd:COG5010   59 PSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138

                         90
                 ....*....|....*
gi 167466175 652 SLAEMHFQKALDINP 666
Cdd:COG5010  139 DEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 567-769 8.38e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 85.04  E-value: 8.38e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH---------YNA 637
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAaaaaallllAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANE 717
Cdd:COG3914   81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 167466175 718 KYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
Cdd:COG3914  161 RLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 545-700 2.16e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 77.31  E-value: 2.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 545 HLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHefvlteeLDKALACF 624
Cdd:COG5010    5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGD-------FEESLALL 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 167466175 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700
Cdd:COG5010   78 EQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
597-780 1.01e-15

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 77.26  E-value: 1.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 597 DPNYAYAYTLLGHEFVLTEELDKALACFR------NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV 670
Cdd:COG4785   29 LLFAAVLALAIALADLALALAAAALAAAAlaaeriDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 671 LLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKL 750
Cdd:COG4785  109 AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKL 188

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 167466175 751 G-QTHLALMNFSWAMDL----DPKGANNQIKEAID 780
Cdd:COG4785  189 DpEKALALLLEDWATAYllqgDTEEARELFKLALA 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 592-734 1.74e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 74.61  E-value: 1.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 592 RAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
Cdd:COG5010   11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167466175 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 580-812 2.01e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 80.90  E-value: 2.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  580 QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGL------------------ 641
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALatilieagefeeaekhad 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  642 ----------------GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705
Cdd:TIGR02917 252 allkkapnsplahylkALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQA 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  706 KFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLP 785
Cdd:TIGR02917 332 RRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQG 411

                         250       260
                  ....*....|....*....|....*..
gi 167466175  786 DDEEPITQEEQIMGTDesqeSSMTDAD 812
Cdd:TIGR02917 412 DPSEAIADLETAAQLD----PELGRAD 434
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
644-735 5.35e-15

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 70.97  E-value: 5.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDtLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 723
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 167466175 724 QELEELKQIVPK 735
Cdd:COG3063   80 AYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 500-634 6.06e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 72.53  E-value: 6.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 500 WVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQK-DVALSVLsKDLTDMDKNSPEAWCAAGNCFS 578
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDlDEAIVLL-HEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 167466175 579 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH 634
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 448-671 3.64e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.57  E-value: 3.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 448 QIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSHLpshhyntgwvlcqiGRAYFELSEYMQAERIFSEVRR 527
Cdd:COG3914   41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA--------------ALLLQALGRYEEALALYRRALA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 528 IENYRVEGMEIYSTTLWHLQKDV-ALSVLSKdLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL 606
Cdd:COG3914  107 LNPDNAEALFNLGNLLLALGRLEeALAALRR-ALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167466175 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
Cdd:COG3914  186 LGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSEL 250
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 504-769 9.06e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 75.51  E-value: 9.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  504 QIGRAYFELSEYMQAERifsEVRRIE--NYRVEGMEIYSTTLWHLQK--DVALSVLSKDLTDMDKNSPEAWCAAGNCFSL 579
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEK---ELRKALslGYPKNQVLPLLARAYLLQGkfQQVLDELPGKTLLDDEGAAELLALRGLAYLG 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  580 QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQ 659
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYR 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  660 KALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLV 739
Cdd:TIGR02917 218 KAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPA 297

                         250       260       270
                  ....*....|....*....|....*....|
gi 167466175  740 YFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKYAPN 327
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 586-772 1.81e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 74.35  E-value: 1.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN 665
Cdd:TIGR02917 552 AVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQ 631

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  666 PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGK 745
Cdd:TIGR02917 632 PDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGD 711

                         170       180
                  ....*....|....*....|....*..
gi 167466175  746 VYKKLGQTHLALMNFSWAMDLDPKGAN 772
Cdd:TIGR02917 712 LYLRQKDYPAAIQAYRKALKRAPSSQN 738
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 551-789 1.17e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 71.65  E-value: 1.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  551 ALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT-------EELDKALAC 623
Cdd:TIGR02917   6 ALLCIALALSACGDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALgdyaaaeKELRKALSL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  624 FRNAIRVNPrhynawyGLGMIYYKQEKFS--LAEMHFQKALDiNPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPK 701
Cdd:TIGR02917  86 GYPKNQVLP-------LLARAYLLQGKFQqvLDELPGKTLLD-DEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  702 NPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDK 781
Cdd:TIGR02917 158 SLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATIL 237


                  ....*...
gi 167466175  782 RYLPDDEE 789
Cdd:TIGR02917 238 IEAGEFEE 245
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 506-769 1.18e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.57  E-value: 1.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  506 GRAYFELSEYMQAERIFSE-VRRIENYRVEGMEIYSTTLWHLQKDVALSVLSkDLTDMDKNSPEAWCAAGNCFSLQREHD 584
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQiLKYAPNSHQARRLLASIQLRLGRVDEAIATLS-PALGLDPDDPAALSLLGEAYLALGDFE 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  585 IAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAeMHFQKALDI 664
Cdd:TIGR02917 381 KAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKA-LAAAKKLEK 459

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  665 N-PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLI 743
Cdd:TIGR02917 460 KqPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILAL 539

                         250       260
                  ....*....|....*....|....*.
gi 167466175  744 GKVYKKLGQTHLALMNFSWAMDLDPK 769
Cdd:TIGR02917 540 AGLYLRTGNEEEAVAWLEKAAELNPQ 565
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 483-695 4.93e-11

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 64.93  E-value: 4.93e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLW-HLQKDVA-----LSVLS 556
Cdd:COG3071  103 QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRAYlGLLRQAArdaeaLKALW 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV--DPNYAYAYTLLghefvLTEELDKALACFRNAIRVNPRH 634
Cdd:COG3071  183 KALPRAERRDPELAAAYARALIALGDHDEAERLLREALKRqwDPRLVRLYGRL-----QGGDPAKQLKRAEKWLKKHPND 257

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 167466175 635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLcHIGVVQHALKKSEKALDTLNKA 695
Cdd:COG3071  258 PDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYA-ELARLLEQLGDPEEAAEHYRKA 317
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 677-768 1.10e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 60.74  E-value: 1.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                         90
                 ....*....|..
gi 167466175 757 LMNFSWAMDLDP 768
Cdd:COG5010  142 KAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
678-769 2.06e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.87  E-value: 2.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQeLEELKQIVPKESLVYFLIGKVYKKLGQTHLAL 757
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 167466175 758 MNFSWAMDLDPK 769
Cdd:COG3063   80 AYLERALELDPS 91
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 618-703 3.27e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 58.08  E-value: 3.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 618 DKALACFRNAIRVNPRHY---NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL---LCHIGVVQHALKKSEKALDT 691
Cdd:COG1729   10 DEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARAT 89

                         90
                 ....*....|..
gi 167466175 692 LNKAIVIDPKNP 703
Cdd:COG1729   90 LEELIKKYPDSE 101
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
450-729 6.58e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.41  E-value: 6.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 450 QAFNLQKAAAEGLMSL---LREMGKGYLALCSYncKEAINILSHLPSHHYNTGWVLCQIGRayfelseymqaerifsevr 526
Cdd:COG0457   33 KALELDPDDAEALYNLglaYLRLGRYEEALADY--EQALELDPDDAEALNNLGLALQALGR------------------- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 527 rienyrvegmeiysttlwhlqkdvalsvlskdltdmdknspeawcaagncfslqreHDIAIKFFQRAIQVDPNYAYAYTL 606
Cdd:COG0457   92 --------------------------------------------------------YEEALEDYDKALELDPDDAEALYN 115

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSE 686
Cdd:COG0457  116 LGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEV 195

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 167466175 687 KALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729
Cdd:COG0457  196 LLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAAL 238
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
665-804 1.04e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 59.54  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 665 NPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 745 KVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQ 804
Cdd:COG4785  149 IALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALALLLEDWATAYLLQ 208
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
563-635 1.35e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.56  E-value: 1.35e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167466175 563 DKNSPEAWCAAGNCFSLQREHDIAIKFfQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHY 635
Cdd:COG3063   22 DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 580-669 1.70e-09

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 56.15  E-value: 1.70e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 580 QREHDIAIKFFQRAIQVDPNYAY---AYTLLGHEFVLTEELDKALACFRNAIRVNPRHY---NAWYGLGMIYYKQEKFSL 653
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELGDYDK 85

                         90
                 ....*....|....*.
gi 167466175 654 AEMHFQKALDINPQSS 669
Cdd:COG1729   86 ARATLEELIKKYPDSE 101
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 551-739 5.45e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.10  E-value: 5.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  551 ALSVLsKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV 630
Cdd:TIGR02917 586 ALAIL-NEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALEL 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  631 NPRHYNAWYGL----------------------------------GMIYYKQEKFSLAEMHFQKALDINPqSSVLLCHIG 676
Cdd:TIGR02917 665 KPDNTEAQIGLaqlllaakrtesakkiakslqkqhpkaalgfeleGDLYLRQKDYPAAIQAYRKALKRAP-SSQNAIKLH 743

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167466175  677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLV 739
Cdd:TIGR02917 744 RALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVV 806
TPR_1 pfam00515
Tetratricopeptide repeat;
635-667 5.66e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 49.34  E-value: 5.66e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 167466175  635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 582-697 9.01e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 54.56  E-value: 9.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 582 EHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH-YNAWYGLGMIYYKQEkfSLAemHFQK 660
Cdd:cd24142   15 NFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLSGGEE--ALQ--YYEK 90

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 167466175 661 ALDInpqssvLLCHIGVVQHALKKSEKALDTLNKAIV 697
Cdd:cd24142   91 GIEI------LEEELQALQAASAEAEEEAEELKRKLS 121
TPR_12 pfam13424
Tetratricopeptide repeat;
636-696 1.37e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.31  E-value: 1.37e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 167466175  636 NAWYGLGMIYYKQEKFSLAEMHFQKALDI--------NPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 597-730 2.57e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 2.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  597 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQeKFSLAEMHFQKALDINPQSSVLLCHIG 676
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLAPNIPAILDTLG 844

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 167466175  677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELK 730
Cdd:TIGR02917 845 WLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKLL 898
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 635-667 3.27e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 47.06  E-value: 3.27e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 167466175   635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 606-669 7.01e-07

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 47.33  E-value: 7.01e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 167466175  606 LLGHEFVLTEELDKALACFRNAIRVN---PRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSS 669
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
TPR_1 pfam00515
Tetratricopeptide repeat;
567-600 3.57e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 43.95  E-value: 3.57e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 167466175  567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 507-733 3.74e-06

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 50.19  E-value: 3.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 507 RAYFELSE-YMQ------AERIFSEVRRIENYRVEG----MEIY-STTLWhlQK--DVALSVLSKDLTDMDKNSPEAWCA 572
Cdd:PRK11788 108 LALQELGQdYLKaglldrAEELFLQLVDEGDFAEGAlqqlLEIYqQEKDW--QKaiDVAERLEKLGGDSLRVEIAHFYCE 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 573 AGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHynawygLGMI-------Y 645
Cdd:PRK11788 186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPEY------LSEVlpklmecY 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 646 YKQEKFSLAEMHFQKALDINPQSSVLLChigVVQHALKK--SEKALDTLNKAIvidPKNP-LCKFHR---ASVLFANEky 719
Cdd:PRK11788 260 QALGDEAEGLEFLRRALEEYPGADLLLA---LAQLLEEQegPEAAQALLREQL---RRHPsLRGFHRlldYHLAEAEE-- 331

                        250
                 ....*....|....
gi 167466175 720 KSALQELEELKQIV 733
Cdd:PRK11788 332 GRAKESLLLLRDLV 345
TPR_12 pfam13424
Tetratricopeptide repeat;
601-667 4.34e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 4.34e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167466175  601 AYAYTLLGHEFVLTEELDKALACFRNAIRV-----NPRH---YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIarrllGPDHpltATTLLNLGRLYLELGRYEEALELLERALALAEK 77
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 643-735 1.04e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.37  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 643 MIYYKQEKFSLAEMHFQKALDINPQSSVL---LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL---CKFHRASVLFAN 716
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYPNSPLApdaLYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLEL 80

                         90
                 ....*....|....*....
gi 167466175 717 EKYKSALQELEELKQIVPK 735
Cdd:COG1729   81 GDYDKARATLEELIKKYPD 99
TPR_11 pfam13414
TPR repeat;
608-648 1.64e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 42.46  E-value: 1.64e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 167466175  608 GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQ 648
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 562-728 1.77e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.44  E-value: 1.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGL 641
Cdd:TIGR00990 394 LNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYY 473

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  642 GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG-VVQHALKKSE------KALDTLNKAIVIDPKNPLCKFHRASVLF 714
Cdd:TIGR00990 474 GELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLpLINKALALFQwkqdfiEAENLCEKALIIDPECDIAVATMAQLLL 553

                         170
                  ....*....|....
gi 167466175  715 ANEKYKSALQELEE 728
Cdd:TIGR00990 554 QQGDVDEALKLFER 567
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 567-600 2.92e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.66  E-value: 2.92e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 167466175   567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 499-606 8.15e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 8.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 499 GWVLcqIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFS 578
Cdd:COG4235   19 GWLL--LGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                         90       100
                 ....*....|....*....|....*...
gi 167466175 579 LQREHDIAIKFFQRAIQVDPNYAYAYTL 606
Cdd:COG4235   97 QQGDYAEAIAAWQKLLALLPADAPARLL 124
TPR_1 pfam00515
Tetratricopeptide repeat;
601-634 1.69e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.33  E-value: 1.69e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 167466175  601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH 634
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 637-667 1.82e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.43  E-value: 1.82e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 167466175  637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 687-797 1.94e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 1.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 687 KALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 167466175 767 DPKGA------------NNQIKEAID--KRYL---PDDEEPITQEEQI 797
Cdd:COG4235   81 DPDNPealyllglaafqQGDYAEAIAawQKLLallPADAPARLLEASI 128
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 454-629 3.76e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 43.36  E-value: 3.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 454 LQKAAA---EGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRien 530
Cdd:COG3071  145 LRKHKAlsaEEAQALERRAYLGLLRQAARDAEALKALWKALPRAERRDPELAAAYARALIALGDHDEAERLLREALK--- 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 531 yrvegmEIYSTTLWHLQKDVALSVLSKDLTDMDK------NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNyAYAY 604
Cdd:COG3071  222 ------RQWDPRLVRLYGRLQGGDPAKQLKRAEKwlkkhpNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAY 294

                        170       180
                 ....*....|....*....|....*
gi 167466175 605 TLLGHEFVLTEELDKALACFRNAIR 629
Cdd:COG3071  295 AELARLLEQLGDPEEAAEHYRKALA 319
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 586-769 4.48e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.82  E-value: 4.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  586 AIKFFQRAI---QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662
Cdd:TIGR00990 313 AARAFEKALdlgKLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKAL 392

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  663 DINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFL 742
Cdd:TIGR00990 393 KLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNY 472

                         170       180
                  ....*....|....*....|....*..
gi 167466175  743 IGKVYKKLGQTHLALMNFSWAMDLDPK 769
Cdd:TIGR00990 473 YGELLLDQNKFDEAIEKFDTAIELEKE 499
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 601-634 4.70e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.20  E-value: 4.70e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 167466175   601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH 634
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 549-628 5.42e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 43.00  E-value: 5.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 549 DVALSVLSKDLtDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYA-YTLLGHefvLTEELDkALACFRNA 627
Cdd:cd24142   17 ELALKFLQRAL-ELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEkYLYLGQ---LSGGEE-ALQYYEKG 91


                 .
gi 167466175 628 I 628
Cdd:cd24142   92 I 92
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 649-768 6.31e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.43  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175  649 EKFSLAEMHFQKALDIN---PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQE 725
Cdd:TIGR00990 308 ESYEEAARAFEKALDLGklgEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEED 387

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 167466175  726 LEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768
Cdd:TIGR00990 388 FDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDP 430
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
641-753 6.82e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 42.18  E-value: 6.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 641 LGMIYYKQEKFSLAEMHFQKAL-DINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNplcKFHRASVLFANeky 719
Cdd:COG4700   95 LADALLELGRYDEAIELYEEALtGIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDF---KSSDAHLLYAR--- 168

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 167466175 720 ksALQEL-------EELKQIV-----PKESLVYfliGKVYKKLGQT 753
Cdd:COG4700  169 --ALEALgdleaaeAELEALArrysgPEARYRY---AKFLARQGRT 209
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 642-757 6.96e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 42.59  E-value: 6.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 642 GMIYYKQEKFSLAEMHFQKALDINPQSsvLLCHIGVVQ--HALKKSEKALDTLNKAIVIDPKNPL-CKFHRASVLFANEK 718
Cdd:COG3071   23 GLLALAEGRYARAEKLLSKAAEHSEAP--LLAYLLAARaaQALGDYERRDEYLAQALELAPEAELaVLLTRAELLLDQGQ 100

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 167466175 719 YKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLAL 757
Cdd:COG3071  101 AEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELL 139
TPR_8 pfam13181
Tetratricopeptide repeat;
635-667 1.07e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.99  E-value: 1.07e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 167466175  635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 683-769 1.16e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 683 KKSEKALDTLNKAIVIDPKNPL---CKFHRASVLFANEKYKSALQELEELKQIVPKESLV---YFLIGKVYKKLGQTHLA 756
Cdd:COG1729    7 GDYDEAIAAFKAFLKRYPNSPLapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKA 86

                         90
                 ....*....|...
gi 167466175 757 LMNFSWAMDLDPK 769
Cdd:COG1729   87 RATLEELIKKYPD 99
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 567-599 1.35e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.73  E-value: 1.35e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 167466175  567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPN 599
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
672-702 2.22e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.24  E-value: 2.22e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 167466175  672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKN 702
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 712-801 3.18e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.17  E-value: 3.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175 712 VLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791
Cdd:COG5010   63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAK 142

                         90
                 ....*....|
gi 167466175 792 TQEEQIMGTD 801
Cdd:COG5010  143 AALQRALGTS 152
TPR_9 pfam13371
Tetratricopeptide repeat;
615-667 4.03e-03

Tetratricopeptide repeat;


Pssm-ID: 463860 [Multi-domain]  Cd Length: 73  Bit Score: 36.81  E-value: 4.03e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 167466175  615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
Cdd:pfam13371   9 EDWERALAVVERLLLLAPDDPEERRDRGLLYAQLGCFQAALEDLEAYLELAPD 61
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 672-702 8.00e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 8.00e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 167466175   672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKN 702
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 9-146 8.79e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.59  E-value: 8.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167466175   9 QAAIWQALNHYAyrDAVFLAER-LYAEVHSEEALFLLATCYYRSGK---AYKAYRLLKGHSCTTPQCKYLLAKCCVDLSK 84
Cdd:COG3914   84 AALLLQALGRYE--EALALYRRaLALNPDNAEALFNLGNLLLALGRleeALAALRRALALNPDFAEAYLNLGEALRRLGR 161

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 167466175  85 LAEGEQILSGGVfnkQKSHDDIVTefgdsacftLSLLGHVYCKTDRLAKGSECYQKSLSLNP 146
Cdd:COG3914  162 LEEAIAALRRAL---ELDPDNAEA---------LNNLGNALQDLGRLEEAIAAYRRALELDP 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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