NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|393185902|ref|NP_001257296|]
View 

transmembrane protein 254 isoform 2 [Homo sapiens]

Protein Classification

transmembrane protein 254( domain architecture ID 10633084)

transmembrane protein 254 (TMEM254) is a DUF4499 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TMEM254 pfam14934
Transmembrane protein 254; This family contains proteins found in eukaryotes, including human ...
 48-137 2.64e-33

Transmembrane protein 254; This family contains proteins found in eukaryotes, including human Transmembrane protein TMEM254 (C10orf57). The exact function of this protein is still unknown, however it is thought to be an integral membrane protein. The protein sequence is 123 amino acids in length and has a mass of approximately 14.2 kDa. The family also includes some longer proteins that possess an N-terminal dehydrogenase domain, pfam01073.


:

Pssm-ID: 464385  Cd Length: 91  Bit Score: 112.35  E-value: 2.64e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 393185902   48 GLGYFAWVVFWPQSIPYQNLGPLGPF--TQYLVDHHHTLLCNGYWLAWLIHVGESLYAIVLCKHKGITSGRAqLLWFLQT 125
Cdd:pfam14934   1 GLGIGMWVVFAPASIPYDSLGPLGLFraLRLLVFRSQTLLRIGFGLAWLIHVLEALYAFKLCRKKGITNAAG-LLWFIQT 79

                          90
                  ....*....|..
gi 393185902  126 FFFGIASLTILI 137
Cdd:pfam14934  80 FLLGFASLRLLL 91
 
Name Accession Description Interval E-value
TMEM254 pfam14934
Transmembrane protein 254; This family contains proteins found in eukaryotes, including human ...
 48-137 2.64e-33

Transmembrane protein 254; This family contains proteins found in eukaryotes, including human Transmembrane protein TMEM254 (C10orf57). The exact function of this protein is still unknown, however it is thought to be an integral membrane protein. The protein sequence is 123 amino acids in length and has a mass of approximately 14.2 kDa. The family also includes some longer proteins that possess an N-terminal dehydrogenase domain, pfam01073.


Pssm-ID: 464385  Cd Length: 91  Bit Score: 112.35  E-value: 2.64e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 393185902   48 GLGYFAWVVFWPQSIPYQNLGPLGPF--TQYLVDHHHTLLCNGYWLAWLIHVGESLYAIVLCKHKGITSGRAqLLWFLQT 125
Cdd:pfam14934   1 GLGIGMWVVFAPASIPYDSLGPLGLFraLRLLVFRSQTLLRIGFGLAWLIHVLEALYAFKLCRKKGITNAAG-LLWFIQT 79

                          90
                  ....*....|..
gi 393185902  126 FFFGIASLTILI 137
Cdd:pfam14934  80 FLLGFASLRLLL 91
 
Name Accession Description Interval E-value
TMEM254 pfam14934
Transmembrane protein 254; This family contains proteins found in eukaryotes, including human ...
 48-137 2.64e-33

Transmembrane protein 254; This family contains proteins found in eukaryotes, including human Transmembrane protein TMEM254 (C10orf57). The exact function of this protein is still unknown, however it is thought to be an integral membrane protein. The protein sequence is 123 amino acids in length and has a mass of approximately 14.2 kDa. The family also includes some longer proteins that possess an N-terminal dehydrogenase domain, pfam01073.


Pssm-ID: 464385  Cd Length: 91  Bit Score: 112.35  E-value: 2.64e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 393185902   48 GLGYFAWVVFWPQSIPYQNLGPLGPF--TQYLVDHHHTLLCNGYWLAWLIHVGESLYAIVLCKHKGITSGRAqLLWFLQT 125
Cdd:pfam14934   1 GLGIGMWVVFAPASIPYDSLGPLGLFraLRLLVFRSQTLLRIGFGLAWLIHVLEALYAFKLCRKKGITNAAG-LLWFIQT 79

                          90
                  ....*....|..
gi 393185902  126 FFFGIASLTILI 137
Cdd:pfam14934  80 FLLGFASLRLLL 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH