|
Name |
Accession |
Description |
Interval |
E-value |
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
33-449 |
1.69e-173 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 491.22 E-value: 1.69e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 33 VVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTV 112
Cdd:cd00751 1 VIVSAVRTPIGRFGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 113 TMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMgqrlsliskfRFNFLAPELPAV 192
Cdd:cd00751 81 NRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDGM----------LDDGLTDPFTGL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 193 SefstsetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGK---DTVTKDNGIRP-SSLEQM 267
Cdd:cd00751 151 S-------MGITAENVAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDeIVPVEVPGRkgpVVVDRDEGPRPdTTLEKL 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 268 AKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQLLLGPTYATPKVLEKAGLT 347
Cdd:cd00751 224 AKLKPAF-KKDGTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDP-AIMGIGPVPAIPKALKRAGLT 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 348 MNDIDAFEFHEAFSGQILANFKAMDSDWfaenymgrktkvglpplEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG 427
Cdd:cd00751 302 LDDIDLIEINEAFAAQALACLKELGLDP-----------------EKVNVNGGAIALGHPLGASGARIVVTLLHELKRRG 364
|
410 420
....*....|....*....|..
gi 528281413 428 GQYGLVAACAAGGQGHAMIVEA 449
Cdd:cd00751 365 GRYGLATMCIGGGQGAAMVIER 386
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
34-448 |
2.77e-165 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 470.56 E-value: 2.77e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 34 VVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVT 113
Cdd:TIGR01930 1 IVAAARTPIGKFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 114 MACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKlMLDLNKAKSMGQRLSLiskfrfnflapelpaVS 193
Cdd:TIGR01930 81 RQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRSLRW-GVKPGNAELEDARLKD---------------LT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 194 EFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGK---DTVTKDNGIRP-SSLEQMA 268
Cdd:TIGR01930 145 DANTGLPMGVTAENLAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDeIVPVTVKGRkgpVTVSSDEGIRPnTTLEKLA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 269 KLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQLLLGPTYATPKVLEKAGLTM 348
Cdd:TIGR01930 225 KLKPAF-DPDGTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDP-EIMGLGPVPAIPKALKKAGLSI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 349 NDIDAFEFHEAFSGQILANFKAMDsdwfaenymgrktkvglPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGG 428
Cdd:TIGR01930 303 SDIDLFEINEAFAAQVLACIKELG-----------------LDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGG 365
|
410 420
....*....|....*....|
gi 528281413 429 QYGLVAACAAGGQGHAMIVE 448
Cdd:TIGR01930 366 RYGLATMCIGGGQGAAVILE 385
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
30-449 |
5.95e-160 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 458.68 E-value: 5.95e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPA 109
Cdd:PRK08963 5 DRIAIVSGLRTPFAKQATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPEL 189
Cdd:PRK08963 85 YSVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVSKKLARALVDLNKARTLGQRLKLFSRLRLRDLLPVP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 190 PAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVV--PFKVPGKDTVTKDNGIRP-SSLEQ 266
Cdd:PRK08963 165 PAVAEYSTGLRMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVmtAHVPPYKQPLEEDNNIRGdSTLED 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 267 MAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGL 346
Cdd:PRK08963 245 YAKLRPAFDRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVWQDMLLGPAYATPLALERAGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 347 TMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKE 426
Cdd:PRK08963 325 TLADLTLIDMHEAFAAQTLANLQMFASERFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLHELRRR 404
|
410 420
....*....|....*....|...
gi 528281413 427 GGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK08963 405 GGGLGLTTACAAGGLGAAMVLEV 427
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
30-449 |
1.47e-152 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 438.35 E-value: 1.47e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPA 109
Cdd:COG0183 2 REVVIVDAVRTPFGRFGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGqrlsliskfrfnflapeL 189
Cdd:COG0183 82 VTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRMNAKLVDPMI-----------------N 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 190 PAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIRP-SSL 264
Cdd:COG0183 145 PGLTDPYTGLSMGETAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDeIVPVEVPDRKgevVVDRDEGPRPdTTL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 265 EQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDqLLLGPTYATPKVLEKA 344
Cdd:COG0183 225 EKLAKLKPAF-KKDGTVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEI-MGIGPVPATRKALARA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 345 GLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaenymgrktkvGLPPlEKFNNWGGSLSLGHPFGATGCRLVMAAANRLR 424
Cdd:COG0183 303 GLTLDDIDLIEINEAFAAQVLAVLREL----------------GLDP-DKVNVNGGAIALGHPLGASGARILVTLLHELE 365
|
410 420
....*....|....*....|....*
gi 528281413 425 KEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:COG0183 366 RRGGRYGLATMCIGGGQGIALIIER 390
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
24-449 |
2.61e-121 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 360.37 E-value: 2.61e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 24 LAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGF 103
Cdd:PRK09268 1 MTMPTVRRVAILGGNRIPFARSNGAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 104 SDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFN 183
Cdd:PRK09268 81 SPYTPAYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSDAPIAVNEGLRKILLELNRAKTTGDRLKALGKLRPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 184 FLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKvpgkdTVTKDNGIRP- 261
Cdd:PRK09268 161 HLAPEIPRNGEPRTGLSMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDlITPFL-----GLTRDNNLRPd 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 262 SSLEQMAKLKPAFIK-PYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQD---PKDQLLLGPTYAT 337
Cdd:PRK09268 236 SSLEKLAKLKPVFGKgGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAAVDfvhGKEGLLMAPAYAV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 338 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVM 417
Cdd:PRK09268 316 PRLLARNGLTLQDFDFYEIHEAFASQVLATLKAWEDEEYCRERLGLDAPLGSIDRSKLNVNGSSLAAGHPFAATGGRIVA 395
|
410 420 430
....*....|....*....|....*....|..
gi 528281413 418 AAANRLRKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK09268 396 TLAKLLAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
30-449 |
1.48e-112 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 337.76 E-value: 1.48e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPA 109
Cdd:PRK08170 3 RPVYIVDGARTPFLKARGGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEANIARVVALRLGCGEKVPA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPE- 188
Cdd:PRK08170 83 WTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLLFSEKMVRWLAGWYAAKSIGQKLAALGKLRPSYLAPVi 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 189 --LPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFkVPGKDTV-TKDNGIRP-SSL 264
Cdd:PRK08170 163 glLRGLTDPVVGLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLKEVVPL-FDRDGKFyDHDDGVRPdSSM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 265 EQMAKLKPAFIKPYGTVTAANSSFLTDGAsAMLIMAEEKALAM-GYKPKAYLRDFMYVSQDPkDQLLLGPTYATPKVLEK 343
Cdd:PRK08170 242 EKLAKLKPFFDRPYGRVTAGNSSQITDGA-CWLLLASEEAVKKyGLPPLGRIVDSQWAALDP-SQMGLGPVHAATPLLQR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 344 AGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 423
Cdd:PRK08170 320 HGLTLEDLDLWEINEAFAAQVLACLAAWADEEYCREQLGLDGALGELDRERLNVDGGAIALGHPVGASGARIVLHLLHAL 399
|
410 420
....*....|....*....|....*.
gi 528281413 424 RKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK08170 400 KRRGTKRGIAAICIGGGQGGAMLLER 425
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
30-449 |
1.16e-105 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 319.02 E-value: 1.16e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPA 109
Cdd:PRK05790 2 KDVVIVSAARTPIGKFGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP--IRHSR---KMRKL-MLDlnkaksmgqrlSLISkfrfn 183
Cdd:PRK05790 82 LTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPhvLPGSRwgqKMGDVeLVD-----------TMIH----- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 184 flapelPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD----TVTKDNG 258
Cdd:PRK05790 146 ------DGLTDAFNGYHMGITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDeIVPVTIKQRKgdpvVVDTDEH 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 259 IRP-SSLEQMAKLKPAFIKPyGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTYAT 337
Cdd:PRK05790 220 PRPdTTAESLAKLRPAFDKD-GTVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPA-IMGIGPVPAI 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 338 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaenymgrktkvGLPPlEKFNNWGGSLSLGHPFGATGCRLVM 417
Cdd:PRK05790 298 RKALEKAGWSLADLDLIEINEAFAAQALAVEKEL----------------GLDP-EKVNVNGGAIALGHPIGASGARILV 360
|
410 420 430
....*....|....*....|....*....|..
gi 528281413 418 AAANRLRKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK05790 361 TLLHEMKRRGAKKGLATLCIGGGQGVALIVER 392
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
32-302 |
2.97e-96 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 289.97 E-value: 2.97e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 32 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHT 111
Cdd:pfam00108 1 VVIVSAARTPFGSFGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 112 VTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRklmldlnkaksmgQRLSLISKFRFNFLAPElpA 191
Cdd:pfam00108 81 INKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDAR-------------SGLKHGDEKKHDLLIPD--G 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 192 VSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP---GKDTVTKDNGIRP-SSLEQ 266
Cdd:pfam00108 146 LTDAFNGYHMGLTAENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDeIVPVTVKgrkGKPTVDKDEGIRPpTTAEP 225
|
250 260 270
....*....|....*....|....*....|....*.
gi 528281413 267 MAKLKPAFIKPyGTVTAANSSFLTDGASAMLIMAEE 302
Cdd:pfam00108 226 LAKLKPAFDKE-GTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
30-451 |
1.60e-86 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 270.32 E-value: 1.60e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPA 109
Cdd:PRK06205 2 RDAVICEPVRTPVGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVPG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIrHSRKMRK--------LM--LDLNKAKSMGQRLSLISK 179
Cdd:PRK06205 82 MQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEF-YTTDMRWgvrgggvqLHdrLARGRETAGGRRFPVPGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 180 frfnflapelpavsefstsetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD----TVT 254
Cdd:PRK06205 161 ---------------------MIETAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDeIVPVTVPQRKgdptVVD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 255 KDNGIRP-SSLEQMAKLKPAFIK--PYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQLLL 331
Cdd:PRK06205 220 RDEHPRAdTTLESLAKLRPIMGKqdPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEP-SRMGI 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 332 GPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEnymgrktkvglpplEKFNNWGGSLSLGHPFGAT 411
Cdd:PRK06205 299 GPVPATEKALARAGLTLDDIDLIELNEAFAAQVLAVLKEWGFGADDE--------------ERLNVNGSGISLGHPVGAT 364
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 528281413 412 GCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYP 451
Cdd:PRK06205 365 GGRILATLLRELQRRQARYGLETMCIGGGQGLAAVFERVN 404
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
29-450 |
5.19e-84 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 263.50 E-value: 5.19e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTP 108
Cdd:PRK08235 1 MSKTVIVSAARTPFGKFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 109 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPI-----RHSRKM-RKLMLDLNKAKSmgqrlsLISKFrf 182
Cdd:PRK08235 81 TETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPYilpgaRWGYRMgDNEVIDLMVADG------LTCAF-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 183 nflapelpavsefsTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD----TVTKDN 257
Cdd:PRK08235 153 --------------SGVHMGVYGGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEeIVPVTIPQRKgdpiVVAKDE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 258 GIRP-SSLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDqLLLGPTYA 336
Cdd:PRK08235 219 APRKdTTIEKLAKLKPVF-DKTGTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKD-FPRTPGYA 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 337 TPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAmdsdwfaenymgrktkVGLPPlEKFNNWGGSLSLGHPFGATGCRLV 416
Cdd:PRK08235 297 INALLEKTGKTVEDIDLFEINEAFAAVALASTEI----------------AGIDP-EKVNVNGGAVALGHPIGASGARII 359
|
410 420 430
....*....|....*....|....*....|....
gi 528281413 417 MAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAY 450
Cdd:PRK08235 360 VTLIHELKRRGGGIGIAAICSGGGQGDAVLIEVH 393
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
29-450 |
3.09e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 256.19 E-value: 3.09e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFLLSGTS------YKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKT-SNVAREAALGA 101
Cdd:PRK06445 1 LEDVYLVDFARTAFSRFRPKdpqkdvFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENwLYGGRHPIFLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 102 GFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIR---HSRKMRKLMLDlnkaksmgqrlslis 178
Cdd:PRK06445 81 RLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGdnpHIEPNPKLLTD--------------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 179 kfrfnflaPELpAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP---GKDTVT 254
Cdd:PRK06445 146 --------PKY-IEYDLTTGYVMGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDeILPIEVEvegKKKVVD 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 255 KDNGIRP-SSLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQLLLGP 333
Cdd:PRK06445 217 VDQSVRPdTSLEKLAKLPPAF-KPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPP-AIMGKGP 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 334 TYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKamdsdwfaenymgrktKVGLPPlEKFNNWGGSLSLGHPFGATGC 413
Cdd:PRK06445 295 VPASKKALEKAGLSVKDIDLWEINEAFAVVVLYAIK----------------ELGLDP-ETVNIKGGAIAIGHPLGATGA 357
|
410 420 430
....*....|....*....|....*....|....*..
gi 528281413 414 RLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAY 450
Cdd:PRK06445 358 RIVGTLARQLQIKGKDYGVATLCVGGGQGGAVVLERV 394
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
30-448 |
8.55e-79 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 249.50 E-value: 8.55e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTS--VPKEVVDyIIFGTVIQEVKTS-NVAREAALGAGFSD 105
Cdd:PRK08947 2 EDVVIVDAIRTPMGRSkGGAFRNVRAEDLSAHLMRSLLARNPalDPAEIDD-IIWGCVQQTLEQGfNIARNAALLAGIPH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 106 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSrkmrklmLDLNkaksmgqrlsliskfrfnfl 185
Cdd:PRK08947 81 SVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMNHG-------VDFH-------------------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 186 apelPAVSEFST--SETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPfkVPGKD------TVTKD 256
Cdd:PRK08947 134 ----PGLSKNVAkaAGMMGLTAEMLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNeIIP--TEGHDadgvlkLFDYD 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 257 NGIRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTY 335
Cdd:PRK08947 208 EVIRPeTTVEALAALRPAFDPVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPS-IMGYGPVP 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 336 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaeNYMGRKTkvglpplEKFNNWGGSLSLGHPFGATGCRL 415
Cdd:PRK08947 287 ATQKALKRAGLSISDIDVFELNEAFAAQSLPCLKDL-------GLLDKMD-------EKVNLNGGAIALGHPLGCSGARI 352
|
410 420 430
....*....|....*....|....*....|...
gi 528281413 416 VMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK08947 353 STTLLNLMERKDAQFGLATMCIGLGQGIATVFE 385
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
30-448 |
3.35e-78 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 248.34 E-value: 3.35e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQ-EVKTSNVAREAALGAGFSDKTP 108
Cdd:PRK09051 3 REVVVVSGVRTAIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPtEPRDMYLSRVAAINAGVPQETP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 109 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP-----IRHSRKMrklmldlNKAKSMGQRLSLISkfrfn 183
Cdd:PRK09051 83 AFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPyllpaARWGARM-------GDAKLVDMMVGALH----- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 184 flapelpavSEFSTSEtMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPG-KDTVT--KDNGI 259
Cdd:PRK09051 151 ---------DPFGTIH-MGVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDqIVPVEIKTrKGEVVfdTDEHV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 260 RPS-SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQLLLGPTYATP 338
Cdd:PRK09051 221 RADtTLEDLAKLKPVFKKENGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDP-EYMGIGPVPATQ 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 339 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaenymgrktkvGLPPlEKFNNWGGSLSLGHPFGATGCRLVMA 418
Cdd:PRK09051 300 KALERAGLTVADLDVIEANEAFAAQACAVTREL----------------GLDP-AKVNPNGSGISLGHPVGATGAIITVK 362
|
410 420 430
....*....|....*....|....*....|
gi 528281413 419 AANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK09051 363 ALYELQRIGGRYALVTMCIGGGQGIAAIFE 392
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
30-451 |
8.35e-78 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 247.31 E-value: 8.35e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTP---FLLSGTSYKdlmPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIqevkTSNV----AREAALGAG 102
Cdd:PLN02644 1 RDVCIVGVARTPiggFLGSLSSLS---ATELGSIAIQAALERAGVDPALVQEVFFGNVL----SANLgqapARQAALGAG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 103 FSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPirhsrkmrKLMLDLNKAKSMGQrLSLISkfrf 182
Cdd:PLN02644 74 LPPSTICTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAP--------KYLPEARKGSRLGH-DTVVD---- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 183 NFLAPELPAV-SEFStsetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGK-----DTVTK 255
Cdd:PLN02644 141 GMLKDGLWDVyNDFG----MGVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWeIVPVEVPGGrgrpsVIVDK 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 256 DNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQLLLGPTY 335
Cdd:PLN02644 217 DEGLGKFDPAKLRKLRPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAP-ELFTTAPAL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 336 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaenymgrktkvGLPPlEKFNNWGGSLSLGHPFGATGCRL 415
Cdd:PLN02644 296 AIPKALKHAGLEASQVDYYEINEAFSVVALANQKLL----------------GLDP-EKVNVHGGAVSLGHPIGCSGARI 358
|
410 420 430
....*....|....*....|....*....|....*.
gi 528281413 416 VMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYP 451
Cdd:PLN02644 359 LVTLLGVLRSKNGKYGVAGICNGGGGASAIVVELMQ 394
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
34-448 |
2.57e-77 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 245.77 E-value: 2.57e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 34 VVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQ-EVKTSNVAREAALGAGFSDKTPAHTV 112
Cdd:PRK07801 6 IVDAVRTPVGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTiGPQAGNIARTSWLAAGLPEEVPGVTV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 113 TMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIrhsrkmrklmldlNKAKSMGQRLSLISKF--------RFNf 184
Cdd:PRK07801 86 DRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPI-------------SSAMTAGEQLGFTSPFaeskgwlhRYG- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 185 lapELPaVSEFstsetmgHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFkvpgkDTVTKDNGIRPSS 263
Cdd:PRK07801 152 ---DQE-VSQF-------RGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNeIVPV-----GGVTVDEGPRETS 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 264 LEQMAKLKPafIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTYATPKVLEK 343
Cdd:PRK07801 216 LEKMAGLKP--LVEGGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPV-FMLTAPIPATRYALEK 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 344 AGLTMNDIDAFEFHEAFSGQILAnfkamdsdWFAEnymgrktkVGLPPlEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 423
Cdd:PRK07801 293 TGLSIDDIDVVEINEAFAPVVLA--------WLKE--------TGADP-AKVNPNGGAIALGHPLGATGAKLMTTLLHEL 355
|
410 420
....*....|....*....|....*
gi 528281413 424 RKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK07801 356 ERTGGRYGLQTMCEGGGTANVTIIE 380
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
31-448 |
2.46e-74 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 238.08 E-value: 2.46e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 31 NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS-NVAREAALGAGFSDKTPA 109
Cdd:PRK07850 3 NPVIVEAVRTPIGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEQSnNITRTAWLHAGLPYHVGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRhsrkmrklmldlnkaKSMGQRLSLISKFRFNFlapEL 189
Cdd:PRK07850 83 TTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLG---------------ANAGPGRGLPRPDSWDI---DM 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 190 PAVSEfstsetmghSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD----------TVTKDNG 258
Cdd:PRK07850 145 PNQFE---------AAERIAKRRGITREDVDAFGLRSQRRAAQAWAEGRFdREISPVQAPVLDeegqptgetrLVTRDQG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 259 IRPSSLEQMAKLKPafIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTYATP 338
Cdd:PRK07850 216 LRDTTMEGLAGLKP--VLEGGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPY-YHLDGPVQATA 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 339 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDwfaenymgrktkvglppLEKFNNWGGSLSLGHPFGATGCRLVMA 418
Cdd:PRK07850 293 KVLEKAGMKIGDIDLVEINEAFASVVLSWAQVHEPD-----------------MDKVNVNGGAIALGHPVGSTGARLITT 355
|
410 420 430
....*....|....*....|....*....|
gi 528281413 419 AANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK07850 356 ALHELERTDKSTALITMCAGGALSTGTIIE 385
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
30-448 |
2.26e-71 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 231.00 E-value: 2.26e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRT-SVPKEVVDYIIFGTVIQEVKTS-NVAREAALGAGFSDKT 107
Cdd:PRK09050 2 TEAFICDAIRTPIGRYGGALSSVRADDLGAVPLKALMARNpGVDWEAVDDVIYGCANQAGEDNrNVARMSALLAGLPVSV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 108 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPirhsrkmrklmLDLNKAKSMGQRLSLI--SKFRFNFL 185
Cdd:PRK09050 82 PGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAP-----------FVMGKADSAFSRQAEIfdTTIGWRFV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 186 APELPAvsEFSTsETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD----TVTKDNGIR 260
Cdd:PRK09050 151 NPLMKA--QYGV-DSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEeIVPVTIPQKKgdpvVVDRDEHPR 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 261 PS-SLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTYATPK 339
Cdd:PRK09050 228 PEtTLEALAKLKPVF-RPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPR-IMGIGPAPATRK 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 340 VLEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaenymgrktkvGLPP-LEKFNNWGGSLSLGHPFGATGCRLVMA 418
Cdd:PRK09050 306 LLARLGLTIDQFDVIELNEAFAAQGLAVLRQL----------------GLADdDARVNPNGGAIALGHPLGMSGARLVLT 369
|
410 420 430
....*....|....*....|....*....|
gi 528281413 419 AANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK09050 370 ALHQLERTGGRYALCTMCIGVGQGIALAIE 399
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
29-448 |
5.55e-69 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 224.24 E-value: 5.55e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFLLSGT-SYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS-NVAREAALGAGFSDK 106
Cdd:PRK07661 1 MREAVIVAGARTPVGKAKKgSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGlNMARNIGALAGLPYT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 107 TPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIrhsrkmrklmldlnkaksMGQRLSLISKfrfnfLA 186
Cdd:PRK07661 81 VPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPM------------------MGHVVRPNPR-----LV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 187 PELPavsEFSTSetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP----GKD--------TV 253
Cdd:PRK07661 138 EAAP---EYYMG--MGHTAEQVAVKYGISREDQDAFAVRSHQRAAKALAEGKFADeIVPVDVTlrtvGENnklqeetiTF 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 254 TKDNGIRP-SSLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMyVSQDPKDQLLLG 332
Cdd:PRK07661 213 SQDEGVRAdTTLEILGKLRPAF-NVKGSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFA-VAGVPPEVMGIG 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 333 PTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWfaenymgrktkvglpplEKFNNWGGSLSLGHPFGATG 412
Cdd:PRK07661 291 PIAAIPKALKLAGLELSDIGLFELNEAFASQSIQVIRELGLDE-----------------EKVNVNGGAIALGHPLGCTG 353
|
410 420 430
....*....|....*....|....*....|....*.
gi 528281413 413 CRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK07661 354 AKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFE 389
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
30-449 |
4.10e-68 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 223.87 E-value: 4.10e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 30 RNVVVVDGVRTPFLLSGT-SYKDLMPHDLARAALTGLLHRTSV-PKEVVDyIIFGTVIQE-VKTSNVAREAALGAGFSDK 106
Cdd:PLN02287 46 DDVVIVAAYRTPICKAKRgGFKDTYPDDLLAPVLKAVVEKTGLnPSEVGD-IVVGTVLAPgSQRANECRMAAFYAGFPET 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 107 TPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRhsrkmrklmldlnkaksmgqrlsliSKFRFNfla 186
Cdd:PLN02287 125 VPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMA-------------------------WEGGVN--- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 187 pelPAVSEFSTSET----MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---------T 252
Cdd:PLN02287 177 ---PRVESFSQAQDcllpMGITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDeIVPVHTKIVDpktgeekpiV 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 253 VTKDNGIRP-SSLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLL 331
Cdd:PLN02287 254 ISVDDGIRPnTTLADLAKLKPVF-KKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPA-VMGI 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 332 GPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQilanfkamdsdwfaenYMGRKTKVGLPPlEKFNNWGGSLSLGHPFGAT 411
Cdd:PLN02287 332 GPAVAIPAAVKAAGLELDDIDLFEINEAFASQ----------------FVYCCKKLGLDP-EKVNVNGGAIALGHPLGAT 394
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 528281413 412 GCRLVMAAANRLRKEG--GQYGLVAACAAGGQGHAMIVEA 449
Cdd:PLN02287 395 GARCVATLLHEMKRRGkdCRFGVVSMCIGTGMGAAAVFER 434
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
29-449 |
1.88e-64 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 212.94 E-value: 1.88e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFllsGTS----YKDLMPHDLARAALTGLLHRTSV--PKEVVDYIIfGTVIQEVKTS-NVAREAALGA 101
Cdd:PRK09052 5 LQDAYIVAATRTPV---GKAprgmFKNTRPDDLLAHVLRSAVAQVPGldPKLIEDAIV-GCAMPEAEQGlNVARIGALLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 102 GFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIrhsrkmrklmldlnkaksMGQRLSLiskfr 181
Cdd:PRK09052 81 GLPNSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPM------------------MGNKPSM----- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 182 fnflAPELPAVSE-FSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKV----PG------ 249
Cdd:PRK09052 138 ----SPAIFARDEnVGIAYGMGLTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDeITPYEIterfPDlatgev 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 250 ---KDTVTKDNGIRP-SSLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAmLIMAEEKAL-AMGYKPKAYLRDFMyVSQD 324
Cdd:PRK09052 214 dvkTRTVDLDEGPRAdTSLEGLAKLKPVF-ANKGSVTAGNSSQTSDGAGA-VILVSEKALkQFNLTPLARFVSFA-VAGV 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 325 PKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKamdsdwfaenymgrktKVGLPPlEKFNNWGGSLSL 404
Cdd:PRK09052 291 PPEIMGIGPIEAIPAALKQAGLKQDDLDWIELNEAFAAQSLAVIR----------------DLGLDP-SKVNPLGGAIAL 353
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 528281413 405 GHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK09052 354 GHPLGATGAIRTATVVHGLRRTNLKYGMVTMCVGTGMGAAGIFER 398
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
33-448 |
3.83e-62 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 207.16 E-value: 3.83e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 33 VVVDGVRTPFLLSGT-SYKDLMPHDLA----RAALTgllhrtSVPK---EVVDYIIFGTVIQEVKT-SNVAREAALGAGF 103
Cdd:PRK07851 5 VIVSTARSPIGRAFKgSLKDMRPDDLAaqmvRAALD------KVPAldpTDIDDLMLGCGLPGGEQgFNMARVVAVLLGY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 104 sDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM---RKLMLDLNKAKSMGQRLSLISKF 180
Cdd:PRK07851 79 -DFLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAKGNSDSLpdtKNPLFAEAQARTAARAEGGAEAW 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 181 RFNFLAPELPAVSEfstseTMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKDTVTKDNGI 259
Cdd:PRK07851 158 HDPREDGLLPDVYI-----AMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFErEITPVTLPDGTVVSTDDGP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 260 RP-SSLEQMAKLKPAFiKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDfMYVSQDPKDQLLLGPTYATP 338
Cdd:PRK07851 233 RAgTTYEKVSQLKPVF-RPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVS-TGVSGLSPEIMGLGPVEASK 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 339 KVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDwfaenymgrktkvglppLEKFNNWGGSLSLGHPFGATGCRLVMA 418
Cdd:PRK07851 311 QALARAGMSIDDIDLVEINEAFAAQVLPSARELGID-----------------EDKLNVSGGAIALGHPFGMTGARITTT 373
|
410 420 430
....*....|....*....|....*....|
gi 528281413 419 AANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK07851 374 LLNNLQTHDKTFGLETMCVGGGQGMAMVLE 403
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
34-448 |
3.09e-61 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 204.35 E-value: 3.09e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 34 VVDGVRTPfllSGTSYKD-----LMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQeV--KTSNVAREAALGAGFSDK 106
Cdd:PRK08242 6 IYDAVRTP---RGKGKKDgslheVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTP-VgdQGADIARTAVLAAGLPET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 107 TPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPirhsrkmrklMLDLNKAKSMGQRLSLISKFrfnflA 186
Cdd:PRK08242 82 VPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVP----------MGSDGGAWAMDPSTNFPTYF-----V 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 187 PElpavsefstsetmGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFK-VPGKDTVTKDNGIRP-SS 263
Cdd:PRK08242 147 PQ-------------GISADLIATKYGFSREDVDAYAVESQQRAAAAWAEGYFAkSVVPVKdQNGLTILDHDEHMRPgTT 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 264 LEQMAKLKPAF-------------IKPYGTV-------TAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQ 323
Cdd:PRK08242 214 MESLAKLKPSFammgemggfdavaLQKYPEVerinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGS 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 324 DPKdQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSdwfaenymgrktkvglpPLEKFNNWGGSLS 403
Cdd:PRK08242 294 DPT-IMLTGPVPATRKALAKAGLTVDDIDLFELNEAFASVVLRFMQALDI-----------------PHDKVNVNGGAIA 355
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 528281413 404 LGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK08242 356 MGHPLGATGAMILGTVLDELERRGKRTALITLCVGGGMGIATIIE 400
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
31-448 |
4.03e-61 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 204.24 E-value: 4.03e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 31 NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS-NVAREAALGAGFSDKTPA 109
Cdd:PRK08131 3 DAYIYDGLRSPFGRHAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSrNVARNALLLAGLPVTVPG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKS-MGQRlsliskfrfnFLAPE 188
Cdd:PRK08131 83 QTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPFVMGKAESAFSRDAKVFDTtIGAR----------FPNPK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 189 LpaVSEFStSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP--GKDT---VTKDNGIRPS 262
Cdd:PRK08131 153 I--VAQYG-NDSMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADeITPIEVPqgRKLPpklVAEDEHPRPS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 263 S-LEQMAKLKPAFIKpyGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTYATPKVL 341
Cdd:PRK08131 230 StVEALTKLKPLFEG--GVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPR-IMGIGPVEAIKKAL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 342 EKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDwFAEnymgrktkvglpplEKFNNWGGSLSLGHPFGATGCRLVMAAAN 421
Cdd:PRK08131 307 ARAGLTLDDMDIIEINEAFASQVLGCLKGLGVD-FDD--------------PRVNPNGGAIAVGHPLGASGARLALTAAR 371
|
410 420
....*....|....*....|....*..
gi 528281413 422 RLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK08131 372 ELQRRGKRYAVVSLCIGVGQGLAMVIE 398
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
34-449 |
9.24e-61 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 203.04 E-value: 9.24e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 34 VVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQE-VKTSNVAREAALGAGFSDKTPAHTV 112
Cdd:PRK06504 6 IVAAARTAGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVgEQATNVARNAVLASKLPESVPGTSI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 113 TMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPirhsrkmrklmldlnkaksMGQRLSLISKFRF-NFLAPEL-- 189
Cdd:PRK06504 86 DRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVP-------------------MGSPSTLPAKNGLgHYKSPGMee 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 190 --PAVsEFStsETMGhsADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPG----KDTVTKDNGIR-P 261
Cdd:PRK06504 147 ryPGI-QFS--QFTG--AEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAeIVPLEITRadgsGEMHTVDEGIRfD 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 262 SSLEQMAKLKPafIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTYATPKVL 341
Cdd:PRK06504 222 ATLEGIAGVKL--IAEGGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPV-IMLEAPLPATERAL 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 342 EKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDwfaenymgrktkvglpPlEKFNNWGGSLSLGHPFGATGCRLVMAAAN 421
Cdd:PRK06504 299 KKAGMKIDDIDLYEVNEAFASVPLAWLKATGAD----------------P-ERLNVNGGAIALGHPLGASGTKLMTTLVH 361
|
410 420
....*....|....*....|....*...
gi 528281413 422 RLRKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK06504 362 ALKQRGKRYGLQTMCEGGGMANVTIVER 389
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
33-448 |
1.80e-58 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 196.91 E-value: 1.80e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 33 VVVDGVRTPFllsGTSYKDL--MPH--DLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKT-SNVAREAALGAGFSDKT 107
Cdd:PRK07108 5 VIVSTARTPL---AKSWRGAfnMTHgaTLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGATgANIARQIALRAGLPVTV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 108 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVpirhSRKMRKLMLD---LNKAKsmgqrlsliskfrfnf 184
Cdd:PRK07108 82 PGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCV----QNEMNRHMLRegwLVEHK---------------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 185 laPELpavsefstSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPF--------KVPG-----K 250
Cdd:PRK07108 142 --PEI--------YWSMLQTAENVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDeIVPItvtagvadKATGrlftkE 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 251 DTVTKDNGIRP-SSLEQMAKLKPAFikPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPkDQL 329
Cdd:PRK07108 212 VTVSADEGIRPdTTLEGVSKIRSAL--PGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEP-DEM 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 330 LLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILanfkamdsdwfaenYMgrKTKVGLPPlEKFNNWGGSLSLGHPFG 409
Cdd:PRK07108 289 GIGPVFAVPKLLKQAGLKVDDIDLWELNEAFAVQVL--------------YC--RDTLGIPM-DRLNVNGGAIAVGHPYG 351
|
410 420 430
....*....|....*....|....*....|....*....
gi 528281413 410 ATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK07108 352 VSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAAGLFE 390
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
29-448 |
8.38e-58 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 195.23 E-value: 8.38e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTP 108
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 109 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMR---KLMLDLN-KAKSMGQRLSLISKFRFnf 184
Cdd:PRK06366 81 KYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLLPSDLRwgpKHLLHKNyKIDDAMLVDGLIDAFYF-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 185 lapelpavsefstsETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFkvpgkDTVTKDNGIRPSS 263
Cdd:PRK06366 159 --------------EHMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNeIVPF-----NDLDRDEGIRKTT 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 264 LEQMAKLKPAFIKPyGTVTAANSSFLTDGASAmLIMAEEKAL-AMGYKPKAYLRDFMYVSQDPKDqLLLGPTYATPKVLE 342
Cdd:PRK06366 220 MEDLAKLPPAFDKN-GILTAGNSAQLSDGGSA-LVMASEKAInEYGLKPIARITGYESASLDPLD-FVEAPIPATRKLLE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 343 KAGLTMNDIDAFEFHEAFS--GQILANFKAMDSdwfaenymgrktkvglpplEKFNNWGGSLSLGHPFGATGCRLVMAAA 420
Cdd:PRK06366 297 KQNKSIDYYDLVEHNEAFSiaSIIVRDQLKIDN-------------------ERFNVNGGAVAIGHPIGNSGSRIIVTLI 357
|
410 420
....*....|....*....|....*...
gi 528281413 421 NRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK06366 358 NALKTRHMKTGLATLCHGGGGAHTLTLE 385
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
309-449 |
2.44e-57 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 185.15 E-value: 2.44e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 309 YKPKAYLRDFMYVSQDPkDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWfaenymgrktkvg 388
Cdd:pfam02803 1 LKPLARIRSYATAGVDP-AIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDP------------- 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528281413 389 lpplEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:pfam02803 67 ----EKVNVNGGAIALGHPLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
29-449 |
3.60e-57 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 193.71 E-value: 3.60e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTP 108
Cdd:PRK06633 2 TKPVYITHAKRTAFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 109 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS----DVPIRHSRKMRKL-MLDLNkaksmgQRLSLISKFRFN 183
Cdd:PRK06633 82 GYTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSlgmhGSYIRAGAKFGDIkMVDLM------QYDGLTDVFSGV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 184 FlapelpavsefstsetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKDTVT---KDNGI 259
Cdd:PRK06633 156 F----------------MGITAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDeILPIEVTIKKTTSlfdHDETV 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 260 RP-SSLEQMAKLKPAFIKPyGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdqlLLG--PTYA 336
Cdd:PRK06633 220 RPdTSLEILSKLRPAFDKN-GVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPS---IMGtaPVPA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 337 TPKVLEKAGLTMNDIDAFEFHEAFSGQILanfkamdsdwfaenYMGRKTKVGLpplEKFNNWGGSLSLGHPFGATGCRLV 416
Cdd:PRK06633 296 SQKALSKAGWSVNDLEVIEVNEAFAAQSI--------------YVNREMKWDM---EKVNINGGAIAIGHPIGASGGRVL 358
|
410 420 430
....*....|....*....|....*....|...
gi 528281413 417 MAAANRLRKEGGQYGLVAACAAGGQGHAMIVEA 449
Cdd:PRK06633 359 ITLIHGLRRAKAKKGLVTLCIGGGMGMAMCVEA 391
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
32-450 |
8.52e-55 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 187.41 E-value: 8.52e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 32 VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHT 111
Cdd:PRK06954 9 IVIASAARTPMAAFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLPLSVGCTT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 112 VTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP-----------IRHSRKMRKLMLD-LNKAKSMGQrlslisk 179
Cdd:PRK06954 89 VNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPyllpkarggmrMGHGQVLDHMFLDgLEDAYDKGR------- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 180 frfnflapelpavsefstseTMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGKD---TVTK 255
Cdd:PRK06954 162 --------------------LMGTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAwEIAPVTVAGKKgdtVIDR 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 256 DNGIRPSSLEQMAKLKPAFIKPyGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTY 335
Cdd:PRK06954 222 DEQPFKANPEKIPTLKPAFSKT-GTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPS-KFTTAPVG 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 336 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSdwfaenymgrktkvglpPLEKFNNWGGSLSLGHPFGATGCRL 415
Cdd:PRK06954 300 AIRKLFEKNGWRAAEVDLFEINEAFAVVTMAAMKEHGL-----------------PHEKVNVNGGACALGHPIGASGARI 362
|
410 420 430
....*....|....*....|....*....|....*
gi 528281413 416 VMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAY 450
Cdd:PRK06954 363 LVTLIGALRARGGKRGVASLCIGGGEATAMGIELI 397
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
29-448 |
2.25e-51 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 178.16 E-value: 2.25e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 29 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTP 108
Cdd:PRK05656 1 MQDVVIVAATRTAIGSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 109 AHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRhsrkmrklmldLNKAKSmGQRL-------SLISKFR 181
Cdd:PRK05656 81 AMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYV-----------LPGART-GLRMghaqlvdSMITDGL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 182 FNflapelpAVSEFStsetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD----TVTKD 256
Cdd:PRK05656 149 WD-------AFNDYH----MGITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDeITPILIPQRKgeplAFATD 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 257 NGIRP-SSLEQMAKLKPAFIKPyGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKdQLLLGPTY 335
Cdd:PRK05656 218 EQPRAgTTAESLAKLKPAFKKD-GSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPA-IMGIGPVS 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 336 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDwfaenymgrktkvglppLEKFNNWGGSLSLGHPFGATGCRL 415
Cdd:PRK05656 296 ATRRCLDKAGWSLAELDLIEANEAFAAQSLAVGKELGWD-----------------AAKVNVNGGAIALGHPIGASGCRV 358
|
410 420 430
....*....|....*....|....*....|...
gi 528281413 416 VMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK05656 359 LVTLLHEMIRRDAKKGLATLCIGGGQGVALAIE 391
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
31-448 |
8.83e-51 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 175.72 E-value: 8.83e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 31 NVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLlhRTSVPKEVvDYIIFGTVIQevKTSNVAREAALGAGFSDKTPAH 110
Cdd:PRK06690 2 RAVIVEAKRTPIGKKNGMLKDYEVQQLAAPLLTFL--SKGMEREI-DDVILGNVVG--PGGNVARLSALEAGLGLHIPGV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 111 TVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRhsrkmrklmldlnkaksmgqrlsliSKFRFnflAPEL- 189
Cdd:PRK06690 77 TIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQ-------------------------NRARF---SPETi 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 190 --PAvsefstsetMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFkvpgkDTVTKDNGIRPSSLEQ 266
Cdd:PRK06690 129 gdPD---------MGVAAEYVAERYNITREMQDEYACLSYKRTLQALEKGYIHEeILSF-----NGLLDESIKKEMNYER 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 267 M-AKLKPAFIKPyGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQlLLGPTYATPKVLEKAG 345
Cdd:PRK06690 195 IiKRTKPAFLHN-GTVTAGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLP-GTGPIFAVNKLLNEMN 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 346 LTMNDIDAFEFHEAFSGQILANFKAMDSdwfaenymgrktkvglpPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRK 425
Cdd:PRK06690 273 MKVEDIDYFEINEAFASKVVACAKELQI-----------------PYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKR 335
|
410 420
....*....|....*....|...
gi 528281413 426 EGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK06690 336 EDMKYGIATLGIGGGIGLALLFE 358
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
34-448 |
1.34e-48 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 171.50 E-value: 1.34e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 34 VVDGVRTPFLLSGT---SYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS-NVAREAALGAGFSDKTPA 109
Cdd:PRK06025 6 IIDAVRTPRGIGKVgkgALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGgDLGRMAALDAGYDIKASG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 110 HTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRK----LMLDLNKAksmgqrlsliskfRFNFL 185
Cdd:PRK06025 86 VTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSYTAAMAAEDMAAgkppLGMGSGNL-------------RLRAL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 186 APElpavsefstsETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVP-GKDTVTKDNGIRP-S 262
Cdd:PRK06025 153 HPQ----------SHQGVCGDAIATMEGITREALDALGLESQRRAARAIKEGRFDkSLVPVYRDdGSVALDHEEFPRPqT 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 263 SLEQMAKLKPAF-------IKPYGTV------------------TAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRD 317
Cdd:PRK06025 223 TAEGLAALKPAFtaiadypLDDKGTTyrglinqkypdleikhvhHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 318 FMYVSQDPKdQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSgqilanfkamdsdWFAENYMgRKTKVglpPLEKFNN 397
Cdd:PRK06025 303 MANMGDDPT-LMLNAPVPAAKKVLAKAGLTKDDIDLWEINEAFA-------------VVAEKFI-RDLDL---DRDKVNV 364
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 528281413 398 WGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 448
Cdd:PRK06025 365 NGGAIALGHPIGATGSILIGTVLDELERRGLKRGLVTMCAAGGMAPAIIIE 415
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
38-448 |
6.91e-41 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 150.34 E-value: 6.91e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 38 VRTPFLLSGTSYKDLmPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACI 117
Cdd:cd00826 8 FGKFGGENGADANDL-AHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIGMNNLCG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 118 SANQAMTTGVGLIASGQCDVIVAGGVELMSdVPIRHSRKMRKLMLDLNKAKSmgqrlsliskfrfnflapelpavsefst 197
Cdd:cd00826 87 SGLRALALAMQLIAGGDANCILAGGFEKME-TSAENNAKEKHIDVLINKYGM---------------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 198 setmghsadrlaaafavsRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPGKD---TVTKDNGIR---PSSLEQMAKL 270
Cdd:cd00826 138 ------------------RACPDAFALAGQAGAEAAEKDGRFKDeFAKFGVKGRKgdiHSDADEYIQfgdEASLDEIAKL 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 271 KPAFIKPyGTVTAANSSFLTDGASAMLIMAEEKA-------LAMGYKPKAYLRDFMYVSQDPKDQLLLG---PTYATPKV 340
Cdd:cd00826 200 RPAFDKE-DFLTAGNACGLNDGAAAAILMSEAEAqkhglqsKAREIQALEMITDMASTFEDKKVIKMVGgdgPIEAARKA 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 341 LEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsDWFAENYMGRKTKVGLPPLEK---FNNWGGSLSLGHPFGATGCRLVM 417
Cdd:cd00826 279 LEKAGLGIGDLDLIEAHDAFAANACATNEAL--GLCPEGQGGALVDRGDNTYGGksiINPNGGAIAIGHPIGASGAAICA 356
|
410 420 430
....*....|....*....|....*....|....*.
gi 528281413 418 AAANRLRKEGGQY-----GLVAACAAGGQGHAMIVE 448
Cdd:cd00826 357 ELCFELKGEAGKRqgagaGLALLCIGGGGGAAMCIE 392
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
54-447 |
2.84e-19 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 88.86 E-value: 2.84e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 54 PHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKtPAHTVTMACISANQAMTTGVGLIASG 133
Cdd:cd00829 16 PLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLLGK-PATRVEAAGASGSAAVRAAAAAIASG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 134 QCDVIVAGGVELMSDVPirhsrkmrklmldlnKAKSMGQRLSLISKFRFN-FLAPELPAVsefstsetMGHSADRLAAAF 212
Cdd:cd00829 95 LADVVLVVGAEKMSDVP---------------TGDEAGGRASDLEWEGPEpPGGLTPPAL--------YALAARRYMHRY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 213 AVSRLEQDEYALRSHSLAKK---AQdegllsdvvpFKVPgkDTVTKDNGIRPSSLeqmaklkpafikPYgtvTAANSSFL 289
Cdd:cd00829 152 GTTREDLAKVAVKNHRNAARnpyAQ----------FRKP--ITVEDVLNSRMIAD------------PL---RLLDCCPV 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 290 TDGASAMLIMAEEKALAMGYKPkAYLR------DFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQ 363
Cdd:cd00829 205 SDGAAAVVLASEERARELTDRP-VWILgvgaasDTPSLSERDDFLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIA 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 364 ILANFKAM------DSDWFAENymGRKTKVGLPPLekfNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQY-----GL 432
Cdd:cd00829 284 ELLALEDLgfcekgEGGKLVRE--GDTAIGGDLPV---NTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARqvpgaRV 358
|
410
....*....|....*
gi 528281413 433 VAACAAGGQGHAMIV 447
Cdd:cd00829 359 GLAHNIGGTGSAAVV 373
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
56-447 |
4.07e-12 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 67.61 E-value: 4.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 56 DLARAALTGLLHRTSVPKEVVDYIIFGTVI--QEVKTSNVAREAALGAGFSDKtPAHTVTMACISANQAMTTGVGLIASG 133
Cdd:PRK06064 24 DLAVEAGLEALEDAGIDGKDIDAMYVGNMSagLFVSQEHIAALIADYAGLAPI-PATRVEAACASGGAALRQAYLAVASG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 134 QCDVIVAGGVELMSDVPirhsrkmrklmldlnkaksmgqrlsliskfrfnflAPElpavsefsTSETMGHSADRLAAAFA 213
Cdd:PRK06064 103 EADVVLAAGVEKMTDVP-----------------------------------TPD--------ATEAIARAGDYEWEEFF 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 214 ----------VSRLEQDEYALRSHSLAK---KAQDEGLLSDVVPFKvpgkdtvtkdngiRPSSLEQMAKLKPAF--IKPY 278
Cdd:PRK06064 140 gatfpglyalIARRYMHKYGTTEEDLALvavKNHYNGSKNPYAQFQ-------------KEITVEQVLNSPPVAdpLKLL 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 279 gtvtaaNSSFLTDGASAMLIMAEEKAlamgykpKAYLRDFMYVS-----------QDPKDQLLLGPT-YATPKVLEKAGL 346
Cdd:PRK06064 207 ------DCSPITDGAAAVILASEEKA-------KEYTDTPVWIKasgqasdtialHDRKDFTTLDAAvVAAEKAYKMAGI 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 347 TMNDIDAFEFHEAFSgqiLANFKAMDSDWFAENYMGRK------TKVG--LPplekFNNWGGSLSLGHPFGATGCRLVMA 418
Cdd:PRK06064 274 EPKDIDVAEVHDCFT---IAEILAYEDLGFAKKGEGGKlaregqTYIGgdIP----VNPSGGLKAKGHPVGATGVSQAVE 346
|
410 420 430
....*....|....*....|....*....|....*...
gi 528281413 419 AANRLRKE---GGQ------YGLvaACAAGGQGHAMIV 447
Cdd:PRK06064 347 IVWQLRGEaekGRQqvigagYGL--THNVGGTGHTAVV 382
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
51-443 |
5.03e-11 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 64.10 E-value: 5.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 51 DLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHtVTMACISANQAMTTGVGLI 130
Cdd:PRK12578 18 DVSVQELAWESIKEALNDAGVSQTDIELVVVGSTAYRGIELYPAPIVAEYSGLTGKVPLR-VEAMCATGLAASLTAYTAV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 131 ASGQCDVIVAGGVELMSDVpirhsrkmrklmlDLNKAKSMGQRlSLISKFRFNFLAPELPAVSEFSTSETMghsadrlaA 210
Cdd:PRK12578 97 ASGLVDMAIAVGVDKMTEV-------------DTSTSLAIGGR-GGNYQWEYHFYGTTFPTYYALYATRHM--------A 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 211 AFAVSRLEQDEYALRSH---SLAKKAQdegllsdvvpFKvpgkdtvtkdngiRPSSLEQMakLKPAFIK-PygtVTAANS 286
Cdd:PRK12578 155 VYGTTEEQMALVSVKAHkygAMNPKAH----------FQ-------------KPVTVEEV--LKSRAISwP---IKLLDS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 287 SFLTDGASAMLIMAEEKALAMGY------KPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAF 360
Cdd:PRK12578 207 CPISDGSATAIFASEEKVKELKIdspvwiTGIGYANDYAYVARRGEWVGFKATQLAARQAYNMAKVTPNDIEVATVHDAF 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 361 SgqiLANFKAMDSDWFAENYMGRK----------TKVGLpplekfNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQY 430
Cdd:PRK12578 287 T---IAEIMGYEDLGFTEKGKGGKfieegqsekgGKVGV------NLFGGLKAKGHPLGATGLSMIYEITKQLRDEAGKL 357
|
410 420
....*....|....*....|.
gi 528281413 431 --------GLVAacAAGGQGH 443
Cdd:PRK12578 358 qqplkkyiGLVH--NVGGTGH 376
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
283-447 |
1.02e-08 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 55.91 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 283 AANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDfMYVSQDPKDQLLL----GPTYATPKVLEKAGLTMNDIDAFEFHE 358
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVS-TAATFDGASMVPAvsgeGLARAARKALEGAGLTPSDIDYVEAHG 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 359 AFSGQILANFKAMDSDWFaenymgrktKVGLPPLEkfnnwGGSLSLGHPFGATG-------CRLVMAAANRLRKEGGQYG 431
Cdd:cd00327 173 TGTPIGDAVELALGLDPD---------GVRSPAVS-----ATLIMTGHPLGAAGlaildelLLMLEHEFIPPTPREPRTV 238
|
170
....*....|....*.
gi 528281413 432 LVAACAAGGQGHAMIV 447
Cdd:cd00327 239 LLLGFGLGGTNAAVVL 254
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
108-439 |
1.02e-07 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 54.13 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 108 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSmgqrlslISKFRFNFL-A 186
Cdd:PTZ00455 112 PAMRVEGACASGGLAVQSAWEALLAGTSDIALVVGVEVQTTVSARVGGDYLARAADYRRQRK-------LDDFTFPCLfA 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 187 PELPAVSEfSTSETMGHSADRLAAAFAVSrlEQDEYAlrsHSLAKKAQDEGLlsdvvpfkvpgkdtvtkdNGIRPSSLEQ 266
Cdd:PTZ00455 185 KRMKYIQE-HGHFTMEDTARVAAKAYANG--NKNPLA---HMHTRKLSLEFC------------------TGASDKNPKF 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 267 MAKlkpAFIKPYGTVTaaNSSFLTDGASAMLIMAEEKALAMGYKP--------KAYLRDFMYVSQDPKDQLLLGPTY-AT 337
Cdd:PTZ00455 241 LGN---ETYKPFLRMT--DCSQVSDGGAGLVLASEEGLQKMGLSPndsrlveiKSLACASGNLYEDPPDATRMFTSRaAA 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 338 PKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDsdwFAE-------NYMGRKTKVGLPPLekfNNWGGSLSLGHPFGA 410
Cdd:PTZ00455 316 QKALSMAGVKPSDLQVAEVHDCFTIAELLMYEALG---IAEyghakdlIRNGATALEGRIPV---NTGGGLLSFGHPVGA 389
|
330 340
....*....|....*....|....*....
gi 528281413 411 TGCRLVMAAANRLRKEGGQYGLVAACAAG 439
Cdd:PTZ00455 390 TGVKQIMEVYRQMKGQCGEYQMKNIPALG 418
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
287-419 |
5.49e-07 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 51.49 E-value: 5.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 287 SFLTDGASAMLIMAEEKALAM----GYKPKAYLRDFMYVSQdpKDQLLL-GPTYATPKVLEKAGLTMNDIDAFEFHEAFS 361
Cdd:PRK07516 213 SLVSDGAAALVLADAETARALqravRFRARAHVNDFLPLSR--RDPLAFeGPRRAWQRALAQAGVTLDDLSFVETHDCFT 290
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528281413 362 GQILANFKAM------------DSDWFAENymGRktkvgLPplekFNNWGGSLSLGHPFGATGCRL-VMAA 419
Cdd:PRK07516 291 IAELIEYEAMglappgqgaraiREGWTAKD--GK-----LP----VNPSGGLKAKGHPIGATGVSMhVLAA 350
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
90-144 |
2.49e-06 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 49.46 E-value: 2.49e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 528281413 90 TSNVAREAALGAGFsdKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 144
Cdd:cd00834 137 PNMAAGQVAIRLGL--RGPNYTVSTACASGAHAIGDAARLIRLGRADVVIAGGAE 189
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
108-144 |
3.00e-06 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 49.32 E-value: 3.00e-06
10 20 30
....*....|....*....|....*....|....*..
gi 528281413 108 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 144
Cdd:COG0304 153 PNYTVSTACASGAHAIGEAYRLIRRGRADVMIAGGAE 189
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
108-146 |
1.75e-05 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 46.09 E-value: 1.75e-05
10 20 30
....*....|....*....|....*....|....*....
gi 528281413 108 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELM 146
Cdd:pfam00109 165 PSVTVDTACSSSLVAIHAAVQSIRSGEADVALAGGVNLL 203
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
50-149 |
2.13e-05 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 46.26 E-value: 2.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 50 KDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKT----SNVAREaaLGAgfsDKTPAHTVTMACISANQAMTT 125
Cdd:COG0332 47 PDETTSDLAVEAARKALEAAGIDPEDIDLIIVATVTPDYLFpstaCLVQHK--LGA---KNAAAFDINAACSGFVYALSV 121
|
90 100
....*....|....*....|....*
gi 528281413 126 GVGLIASGQCD-VIVAGGvELMSDV 149
Cdd:COG0332 122 AAALIRSGQAKnVLVVGA-ETLSRI 145
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
55-145 |
3.21e-05 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 45.13 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 55 HDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSdKTPAHTVTMACISANQAMTTGVGLIASGQ 134
Cdd:cd00327 8 SELGFEAAEQAIADAGLSKGPIVGVIVGTTGGSGEFSGAAGQLAYHLGIS-GGPAYSVNQACATGLTALALAVQQVQNGK 86
|
90
....*....|.
gi 528281413 135 CDVIVAGGVEL 145
Cdd:cd00327 87 ADIVLAGGSEE 97
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
108-170 |
2.99e-03 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 39.73 E-value: 2.99e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528281413 108 PAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSM 170
Cdd:cd00828 154 PIKTPVGACATALEALDLAVEAIRSGKADIVVVGGVEDPLEEGLSGFANMGALSTAEEEPEEM 216
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
56-149 |
4.33e-03 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 39.06 E-value: 4.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 56 DLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVARE--AALGAGfsdKTPAHTVTMACISANQAMTTGVGLIASG 133
Cdd:cd00830 52 DLAVEAAKKALEDAGIDADDIDLIIVATSTPDYLFPATACLvqARLGAK---NAAAFDINAACSGFLYGLSTAAGLIRSG 128
|
90
....*....|....*..
gi 528281413 134 QCD-VIVAGGvELMSDV 149
Cdd:cd00830 129 GAKnVLVVGA-ETLSRI 144
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
336-412 |
5.09e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 39.11 E-value: 5.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528281413 336 ATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMdsdwfaenymgrktkvGLPP---LEKF--------------NNW 398
Cdd:PRK08256 269 AAQQVYEQAGIGPEDIDVVELHDCFSANELLTYEAL----------------GLCPegeAEKFiddgdntyggrwvvNPS 332
|
90
....*....|....
gi 528281413 399 GGSLSLGHPFGATG 412
Cdd:PRK08256 333 GGLLSKGHPLGATG 346
|
|
| |
