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Conserved domains on  [gi|550544164|ref|NP_001272383|]
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microtubule-associated protein tau isoform 3 [Mus musculus]

Protein Classification

PHA02682 and Tubulin-binding domain-containing protein( domain architecture ID 13285099)

PHA02682 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 206-235 1.55e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 55.49  E-value: 1.55e-10
                          10        20        30
                  ....*....|....*....|....*....|
gi 550544164  206 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 235
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 237-267 1.08e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.18  E-value: 1.08e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 550544164  237 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 267
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 183-204 3.29e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 45.86  E-value: 3.29e-07
                          10        20
                  ....*....|....*....|..
gi 550544164  183 DLKNVRSKIGSTENLKHQPGGG 204
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA02682 super family cl31817
ORF080 virion core protein; Provisional
 83-185 3.47e-04

ORF080 virion core protein; Provisional


The actual alignment was detected with superfamily member PHA02682:

Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 41.77  E-value: 3.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  83 ATPRGAA-SPAQKGTSNATRIPAkttPSPKTPPGSGE---PPKSGERSGYSSPGSPGTPGSRSRTPSLPTP---PTREPK 155
Cdd:PHA02682  89 AAPAPACpACAPAAPAPAVTCPA---PAPACPPATAPtcpPPAVCPAPARPAPACPPSTRQCPPAPPLPTPkpaPAAKPI 165

                         90       100       110
                 ....*....|....*....|....*....|
gi 550544164 156 KVAVVRTPPKSPSASKSRLQTAPVPMPDLK 185
Cdd:PHA02682 166 FLHNQLPPPDYPAASCPTIETAPAASPVLE 195
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 206-235 1.55e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 55.49  E-value: 1.55e-10
                          10        20        30
                  ....*....|....*....|....*....|
gi 550544164  206 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 235
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 237-267 1.08e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.18  E-value: 1.08e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 550544164  237 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 267
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 183-204 3.29e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 45.86  E-value: 3.29e-07
                          10        20
                  ....*....|....*....|..
gi 550544164  183 DLKNVRSKIGSTENLKHQPGGG 204
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 83-185 3.47e-04

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 41.77  E-value: 3.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  83 ATPRGAA-SPAQKGTSNATRIPAkttPSPKTPPGSGE---PPKSGERSGYSSPGSPGTPGSRSRTPSLPTP---PTREPK 155
Cdd:PHA02682  89 AAPAPACpACAPAAPAPAVTCPA---PAPACPPATAPtcpPPAVCPAPARPAPACPPSTRQCPPAPPLPTPkpaPAAKPI 165

                         90       100       110
                 ....*....|....*....|....*....|
gi 550544164 156 KVAVVRTPPKSPSASKSRLQTAPVPMPDLK 185
Cdd:PHA02682 166 FLHNQLPPPDYPAASCPTIETAPAASPVLE 195
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 206-235 1.55e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 55.49  E-value: 1.55e-10
                          10        20        30
                  ....*....|....*....|....*....|
gi 550544164  206 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 235
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 237-267 1.08e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.18  E-value: 1.08e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 550544164  237 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 267
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 183-204 3.29e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 45.86  E-value: 3.29e-07
                          10        20
                  ....*....|....*....|..
gi 550544164  183 DLKNVRSKIGSTENLKHQPGGG 204
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 83-185 3.47e-04

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 41.77  E-value: 3.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  83 ATPRGAA-SPAQKGTSNATRIPAkttPSPKTPPGSGE---PPKSGERSGYSSPGSPGTPGSRSRTPSLPTP---PTREPK 155
Cdd:PHA02682  89 AAPAPACpACAPAAPAPAVTCPA---PAPACPPATAPtcpPPAVCPAPARPAPACPPSTRQCPPAPPLPTPkpaPAAKPI 165

                         90       100       110
                 ....*....|....*....|....*....|
gi 550544164 156 KVAVVRTPPKSPSASKSRLQTAPVPMPDLK 185
Cdd:PHA02682 166 FLHNQLPPPDYPAASCPTIETAPAASPVLE 195
PHA03378 PHA03378
EBNA-3B; Provisional
 85-182 7.33e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.59  E-value: 7.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  85 PRGAASPAQKGTSNATRIPakttpSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKvAVVRTPP 164
Cdd:PHA03378 707 PAAPPGRAQRPAAATGRAR-----PPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGA-PTPQPPP 780

                         90
                 ....*....|....*...
gi 550544164 165 KSPSASKSRLQTAPVPMP 182
Cdd:PHA03378 781 QAPPAPQQRPRGAPTPQP 798
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 63-182 8.35e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 8.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  63 RTGNDEKKAKGADGKTGAKIATPRGAASPAQKGTSNA--TRIPAKTTPSPKTPPGSGEPPKSGeRSGYSSPGSPGTPGSR 140
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPapAAAPAAAASAPAAPPAAAPPAPVA-APAAAAPAAAPAAAPA 443

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 550544164 141 SRT--PSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMP 182
Cdd:PRK14951 444 AVAlaPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAAR 487
PHA03247 PHA03247
large tegument protein UL36; Provisional
 83-184 8.63e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 8.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   83 ATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPG---SPGTPGSR----SRTPSLPTPPTREP- 154
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsvAPGGDVRRrppsRSPAAKPAAPARPPv 2883

                          90       100       110
                  ....*....|....*....|....*....|
gi 550544164  155 KKVAVVRTPPKSPSASKSRLQTAPVPMPDL 184
Cdd:PHA03247 2884 RRLARPAVSRSTESFALPPDQPERPPQPQA 2913
PHA03247 PHA03247
large tegument protein UL36; Provisional
 68-174 1.80e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 1.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   68 EKKAKGADGKTGAKIATPRGAA-----------------SPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSgersgySS 130
Cdd:PHA03247  372 RHHPKRASLPTRKRRSARHAATpfargpggddqtrpaapVPASVPTPAPTPVPASAPPPPATPLPSAEPGSD------DG 445

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 550544164  131 PGSP--GTPGSRSRTPSLPTPPTREPKKVAVVRT--PPKSPSASKSRL 174
Cdd:PHA03247  446 PAPPpeRQPPAPATEPAPDDPDDATRKALDALRErrPPEPPGADLAEL 493
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 84-197 2.10e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.18  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  84 TPRGAASPAQkgTSNATRIPAKTTPSPKTPPGSGEPpksgersgysSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP 163
Cdd:PRK14950 361 VPVPAPQPAK--PTAAAPSPVRPTPAPSTRPKAAAA----------ANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA 428

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 550544164 164 PKSPSASkSRLQTAPV---PMPDLKNVRSKIGSTENL 197
Cdd:PRK14950 429 PKLTRAA-IPVDEKPKytpPAPPKEEEKALIADGDVL 464
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 24-167 2.24e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.06  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  24 QEGDMD-HGLKAEEAGIGDTPnqeDQAAGHVTQARVASKDRTGNDEKKAKGADGKTGAKIATPRgaASPAQKGTSNATRI 102
Cdd:PTZ00449 500 EEEDSDkHDEPPEGPEASGLP---PKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKK--PGPAKEHKPSKIPT 574

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164 103 PAKTTPSPKTP--PGSGEPPKSGER----SGYSSPGSPGTPGS-----------RSRTPSLPTPPTR-----EPKKVAVV 160
Cdd:PTZ00449 575 LSKKPEFPKDPkhPKDPEEPKKPKRprsaQRPTRPKSPKLPELldipkspkrpeSPKSPKRPPPPQRpsspeRPEGPKII 654


                 ....*....
gi 550544164 161 RT--PPKSP 167
Cdd:PTZ00449 655 KSpkPPKSP 663
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
21-151 4.31e-03

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 38.57  E-value: 4.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  21 LQDQEGDMDHGLKAEEAGIgdtPNQEDQAAGHVTQARVASKDRTGNDEKKAKGADGKTGAKIATPRGAASPAQKGTSNAT 100
Cdd:PRK13335  33 IQSTKVDKVPTLKAERLAM---INITAGANSATTQAANTRQERTPKLEKAPNTNEEKTSASKIEKISQPKQEEQKSLNIS 109

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 550544164 101 RIPAKTTPSPKTPPGSGEPPKSgersgYSSPGSPGTPGSRSRTPSL-PTPPT 151
Cdd:PRK13335 110 ATPAPKQEQSQTTTESTTPKTK-----VTTPPSTNTPQPMQSTKSDtPQSPT 156
PHA03291 PHA03291
envelope glycoprotein I; Provisional
 91-173 5.40e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 38.40  E-value: 5.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  91 PAQKGTSNATRIPAKTTPSPKT--PPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTrepKKVAVVRTPPKSPS 168
Cdd:PHA03291 199 PADVFVPATPRPTPRTTASPETtpTPSTTTSPPSTTIPAPSTTIAAPQAGTTPEAEGTPAPPT---PGGGEAPPANATPA 275


                 ....*
gi 550544164 169 ASKSR 173
Cdd:PHA03291 276 PEASR 280
PHA03247 PHA03247
large tegument protein UL36; Provisional
 76-182 5.58e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 5.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   76 GKTGAKIATPRGAASPAQKGTSNATRIPAKTTPsPKTPPGSGEPPKSGERSGYSSPGSPGTP-----GSRSRTPSLPTPP 150
Cdd:PHA03247 2724 GPAAARQASPALPAAPAPPAVPAGPATPGGPAR-PARPPTTAGPPAPAPPAAPAAGPPRRLTrpavaSLSESRESLPSPW 2802

                          90       100       110
                  ....*....|....*....|....*....|..
gi 550544164  151 TREPKKVAVvrtPPKSPSASKSRLQTAPVPMP 182
Cdd:PHA03247 2803 DPADPPAAV---LAPAAALPPAASPAGPLPPP 2831
PHA03247 PHA03247
large tegument protein UL36; Provisional
 100-182 5.98e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  100 TRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSPGTPgSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPV 179
Cdd:PHA03247 2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP-ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946


                  ...
gi 550544164  180 PMP 182
Cdd:PHA03247 2947 TDP 2949
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 25-183 6.77e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 38.61  E-value: 6.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   25 EGDMDHGLKAEEAGIGDTPNQEDQAAGHVTQARVASKDRTGNDEKKAKGADGKTGAKIATPRGAASPAQKGTSNATRIPA 104
Cdd:PHA03307   28 PGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPT 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  105 KTTPSPKTPPGSGEPPKSGErsgySSPGSPGTPGSRSRTPSLPTPPTREPKKVAVvrtPPKSPSASKSRLQTA-PVPMPD 183
Cdd:PHA03307  108 PPGPSSPDPPPPTPPPASPP----PSPAPDLSEMLRPVGSPGPPPAASPPAAGAS---PAAVASDAASSRQAAlPLSSPE 180
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 29-202 7.44e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 38.61  E-value: 7.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   29 DHGLKAEEAGIGDTPnQEDQAAGHVTQARVASKDRTGNdEKKAKGADGKTGAKIATPRGAASPAQKGTSNAtriPAKTTP 108
Cdd:PHA03307  237 SDSSSSESSGCGWGP-ENECPLPRPAPITLPTRIWEAS-GWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---GPAPSS 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164  109 SPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVR 188
Cdd:PHA03307  312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391

                         170
                  ....*....|....
gi 550544164  189 SKIGSTENLKHQPG 202
Cdd:PHA03307  392 AAVAGRARRRDATG 405
PHA03247 PHA03247
large tegument protein UL36; Provisional
 83-182 7.61e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.38  E-value: 7.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   83 ATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSS-PGSPGTPGSRSRTPSLP----TPPTREPKKV 157
Cdd:PHA03247 2671 GRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSAtPLPPGPAAARQASPALPaapaPPAVPAGPAT 2750

                          90       100
                  ....*....|....*....|....*
gi 550544164  158 AVVRTPPKSPSASKSRLQTAPVPMP 182
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAP 2775
PHA03247 PHA03247
large tegument protein UL36; Provisional
 83-182 9.86e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.00  E-value: 9.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550544164   83 ATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPtrePKKVAVVRT 162
Cdd:PHA03247 2718 ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTR---PAVASLSES 2794

                          90       100
                  ....*....|....*....|
gi 550544164  163 PPKSPSASKSRLQTAPVPMP 182
Cdd:PHA03247 2795 RESLPSPWDPADPPAAVLAP 2814
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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