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Conserved domains on  [gi|556503432|ref|NP_001273281|]
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olfactomedin-like protein 3 isoform 2 [Homo sapiens]

Protein Classification

olfactomedin domain-containing protein( domain architecture ID 10490292)

olfactomedin domain-containing protein adopts a five-bladed beta-propeller structure, similar to gliomedin that interacts with neuronal cell adhesion molecules such as neurofascin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
119-379 2.09e-106

Olfactomedin-like domain;


:

Pssm-ID: 460482  Cd Length: 246  Bit Score: 312.93  E-value: 2.09e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  119 ISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLD-GTQNDTAFVFPRLRDFTLAmaaRKASRVRVPFPWVGTGQLVYGG 197
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTDrGTSGNTLREYASLDDFKNG---SPSKKYKLPYPWQGTGHVVYNG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  198 FLYFARrppgrpggggemENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAVYATREDDRH 275
Cdd:pfam02191  78 SLYYNK------------YNSRNIVKYDLTTRTVAARRVLPGAGYnnRFPYSWGGHTDIDLAVDENGLWVIYATEENEGN 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  276 LCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNtRPASRARIQCSFDasgTLT-PERAALPYFPRRYGAHAS 354
Cdd:pfam02191 146 IVVSKLDPETLEVEQTWNTSYPKRSAGNAFMVCGVLYAVRS-VNTRREEIFYAFD---TYTgKEEAVSIPFPNRYGKISM 221

                         250       260
                  ....*....|....*....|....*
gi 556503432  355 LRYNPRERQLYAWDDGYQIVYKLEM 379
Cdd:pfam02191 222 LDYNPRDKKLYAWDDGYQVTYPVTF 246
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
119-379 2.09e-106

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 312.93  E-value: 2.09e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  119 ISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLD-GTQNDTAFVFPRLRDFTLAmaaRKASRVRVPFPWVGTGQLVYGG 197
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTDrGTSGNTLREYASLDDFKNG---SPSKKYKLPYPWQGTGHVVYNG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  198 FLYFARrppgrpggggemENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAVYATREDDRH 275
Cdd:pfam02191  78 SLYYNK------------YNSRNIVKYDLTTRTVAARRVLPGAGYnnRFPYSWGGHTDIDLAVDENGLWVIYATEENEGN 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  276 LCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNtRPASRARIQCSFDasgTLT-PERAALPYFPRRYGAHAS 354
Cdd:pfam02191 146 IVVSKLDPETLEVEQTWNTSYPKRSAGNAFMVCGVLYAVRS-VNTRREEIFYAFD---TYTgKEEAVSIPFPNRYGKISM 221

                         250       260
                  ....*....|....*....|....*
gi 556503432  355 LRYNPRERQLYAWDDGYQIVYKLEM 379
Cdd:pfam02191 222 LDYNPRDKKLYAWDDGYQVTYPVTF 246
OLF smart00284
Olfactomedin-like domains;
133-379 2.85e-48

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 164.24  E-value: 2.85e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432   133 GPAGLWTKDPL---GQTEKIYVLD--GTQNDTAFVFPRLRDFtlaMAARKASRVRVPFPWVGTGQLVYGGFLYFarrppg 207
Cdd:smart00284  18 GKSGAWMKDPLwntTKKSLYWYMPlnTRVLRSVREYSSMSDF---QMGKNPTDHPLPHAGQGTGVVVYNGSLYF------ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432   208 rpggggEMENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQT 285
Cdd:smart00284  89 ------NKFNSHDICRFDLTTETYQKEPLLNGAGYnnRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVISKLNPAT 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432   286 LDTEQQWDTPCPRENAEAAFVICGTLYVVyNTRPASRARIQCSFDaSGTLTPERAALPyFPRRYGAHASLRYNPRERQLY 365
Cdd:smart00284 163 LTIENTWITTYNKRSASNAFMICGILYVT-RSLGSKGEKVFYAYD-TNTGKEGHLDIP-FENMYEYISMLDYNPNDRKLY 239

                          250
                   ....*....|....
gi 556503432   366 AWDDGYQIVYKLEM 379
Cdd:smart00284 240 AWNNGHLVHYDIAL 253
 
Name Accession Description Interval E-value
OLF pfam02191
Olfactomedin-like domain;
119-379 2.09e-106

Olfactomedin-like domain;


Pssm-ID: 460482  Cd Length: 246  Bit Score: 312.93  E-value: 2.09e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  119 ISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLD-GTQNDTAFVFPRLRDFTLAmaaRKASRVRVPFPWVGTGQLVYGG 197
Cdd:pfam02191   1 LVSVSKPVTVKLSGGKYGAWMKDPLPPSDKIYVTDrGTSGNTLREYASLDDFKNG---SPSKKYKLPYPWQGTGHVVYNG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  198 FLYFARrppgrpggggemENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAVYATREDDRH 275
Cdd:pfam02191  78 SLYYNK------------YNSRNIVKYDLTTRTVAARRVLPGAGYnnRFPYSWGGHTDIDLAVDENGLWVIYATEENEGN 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432  276 LCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNtRPASRARIQCSFDasgTLT-PERAALPYFPRRYGAHAS 354
Cdd:pfam02191 146 IVVSKLDPETLEVEQTWNTSYPKRSAGNAFMVCGVLYAVRS-VNTRREEIFYAFD---TYTgKEEAVSIPFPNRYGKISM 221

                         250       260
                  ....*....|....*....|....*
gi 556503432  355 LRYNPRERQLYAWDDGYQIVYKLEM 379
Cdd:pfam02191 222 LDYNPRDKKLYAWDDGYQVTYPVTF 246
OLF smart00284
Olfactomedin-like domains;
133-379 2.85e-48

Olfactomedin-like domains;


Pssm-ID: 128580  Cd Length: 255  Bit Score: 164.24  E-value: 2.85e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432   133 GPAGLWTKDPL---GQTEKIYVLD--GTQNDTAFVFPRLRDFtlaMAARKASRVRVPFPWVGTGQLVYGGFLYFarrppg 207
Cdd:smart00284  18 GKSGAWMKDPLwntTKKSLYWYMPlnTRVLRSVREYSSMSDF---QMGKNPTDHPLPHAGQGTGVVVYNGSLYF------ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432   208 rpggggEMENTLQLIKFHLANRTVVDSSVFPAEGL--IPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQT 285
Cdd:smart00284  89 ------NKFNSHDICRFDLTTETYQKEPLLNGAGYnnRFPYAWGGFSDIDLAVDENGLWVIYATEQNAGKIVISKLNPAT 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556503432   286 LDTEQQWDTPCPRENAEAAFVICGTLYVVyNTRPASRARIQCSFDaSGTLTPERAALPyFPRRYGAHASLRYNPRERQLY 365
Cdd:smart00284 163 LTIENTWITTYNKRSASNAFMICGILYVT-RSLGSKGEKVFYAYD-TNTGKEGHLDIP-FENMYEYISMLDYNPNDRKLY 239

                          250
                   ....*....|....
gi 556503432   366 AWDDGYQIVYKLEM 379
Cdd:smart00284 240 AWNNGHLVHYDIAL 253
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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