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Conserved domains on  [gi|556695389|ref|NP_001273359|]
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RNA polymerase-associated protein LEO1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Leo1 super family cl04368
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 387-476 2.71e-29

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


The actual alignment was detected with superfamily member pfam04004:

Pssm-ID: 461126  Cd Length: 163  Bit Score: 113.82  E-value: 2.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  387 SMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMA 464
Cdd:pfam04004  72 SLSLQLGDEHFDIQSKPLQDDHTYLAARHESSelLQTQGHITEQLTFRPTSTQSDTHRRLTAALAARHKKTGAKIMLIIT 151

                          90
                  ....*....|..
gi 556695389  465 GRDPECQRTEMI 476
Cdd:pfam04004 152 TEDPELEKKEAE 163
MSCRAMM_ClfA super family cl41352
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 9-361 6.21e-15

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


The actual alignment was detected with superfamily member NF033609:

Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 78.41  E-value: 6.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   9 GSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSErSDNRS 88
Cdd:NF033609 566 GSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASD-SDSDS 644

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  89 EASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSD-DEER 167
Cdd:NF033609 645 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDS 724

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 168 AQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEkANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSD 247
Cdd:NF033609 725 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 803

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 248 DERPQASDEEhrhSDDEEEQDHKSESARGSDSEDEvlrmkrknaiaSDSEADSDTEVPKDNSGTMDLFGGAD-DISSGSD 326
Cdd:NF033609 804 SDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSESDSNsDSESGSN 869

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 556695389 327 GEDKPP-TPGQPVDENGLPQDQQEEEPIPETRIEVE 361
Cdd:NF033609 870 NNVVPPnSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
 
Name Accession Description Interval E-value
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 387-476 2.71e-29

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


Pssm-ID: 461126  Cd Length: 163  Bit Score: 113.82  E-value: 2.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  387 SMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMA 464
Cdd:pfam04004  72 SLSLQLGDEHFDIQSKPLQDDHTYLAARHESSelLQTQGHITEQLTFRPTSTQSDTHRRLTAALAARHKKTGAKIMLIIT 151

                          90
                  ....*....|..
gi 556695389  465 GRDPECQRTEMI 476
Cdd:pfam04004 152 TEDPELEKKEAE 163
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 9-361 6.21e-15

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 78.41  E-value: 6.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   9 GSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSErSDNRS 88
Cdd:NF033609 566 GSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASD-SDSDS 644

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  89 EASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSD-DEER 167
Cdd:NF033609 645 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDS 724

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 168 AQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEkANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSD 247
Cdd:NF033609 725 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 803

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 248 DERPQASDEEhrhSDDEEEQDHKSESARGSDSEDEvlrmkrknaiaSDSEADSDTEVPKDNSGTMDLFGGAD-DISSGSD 326
Cdd:NF033609 804 SDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSESDSNsDSESGSN 869

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 556695389 327 GEDKPP-TPGQPVDENGLPQDQQEEEPIPETRIEVE 361
Cdd:NF033609 870 NNVVPPnSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 1-268 6.06e-11

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 65.79  E-value: 6.06e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389     1 MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFG-DDSEDEGASHHSGSDN 79
Cdd:TIGR00927  627 LGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERkGEQEGEGEIEAKEADH 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    80 HSERSDNRSEASERSDHE-DNDPSDVDQHSGSEapnDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEk 158
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEgTEDEGEIETGEEGE---EVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGE- 782

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   159 IQNSDDEErAQGSDEDKLQNSDDDEKMQNTDDEERpqlSDDERQQLSEEEKANSDDERPVASDNDDEKQNS---DDEEQP 235
Cdd:TIGR00927  783 IQAGEDGE-MKGDEGAEGKVEHEGETEAGEKDEHE---GQSETQADDTEVKDETGEQELNAENQGEAKQDEkgvDGGGGS 858

                          250       260       270
                   ....*....|....*....|....*....|...
gi 556695389   236 QLSDEEKMQNSDDERPQASDEEHRHSDDEEEQD 268
Cdd:TIGR00927  859 DGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 55-328 9.94e-10

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 61.85  E-value: 9.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  55 QPSNKELFGDDSEDEGASHhSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDdEDEGHRSDGGSHHSEAEG 134
Cdd:NF033609 550 EPGEIEPIPEDSDSDPGSD-SGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASD-SDSASDSDSASDSDSASD 627

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 135 SEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEkANSDD 214
Cdd:NF033609 628 SDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDS 706

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 215 ERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEhRHSDDEEEQDHKSESARGSDSEDEVlrmkrknaiAS 294
Cdd:NF033609 707 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDS---------DS 776

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 556695389 295 DSEADSDTEVPKDNSGTMDLFGGAD-DISSGSDGE 328
Cdd:NF033609 777 DSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSD 811
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 101-329 2.86e-07

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 53.76  E-value: 2.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 101 PSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSD 180
Cdd:NF033609 558 PEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 637

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 181 DDEKMQNTDDEERPQLSDDERQQLSEeekANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDeehrh 260
Cdd:NF033609 638 SDSDSDSDSDSDSDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD----- 709

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556695389 261 SDDEEEQDHKSESARGSDSEDEvlrmkrknaiaSDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGED 329
Cdd:NF033609 710 SDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 767
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 50-284 1.12e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 48.36  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  50 RGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPND-----DEDEGHRSD 124
Cdd:PRK12678  59 RGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAaqareRRERGEAAR 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 125 GGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDklQNSDDDEKMQNTDDEERpqlsddeRQQL 204
Cdd:PRK12678 139 RGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERG--ERGRREERGRDGDDRDR-------RDRR 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 205 SEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSD----SE 280
Cdd:PRK12678 210 EQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNERepelRE 289


                 ....
gi 556695389 281 DEVL 284
Cdd:PRK12678 290 DDVL 293
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 140-284 1.24e-04

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 45.31  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  140 SDDEKWGREDKSDQSDDEkiqnsDDEERAQGSDEDKLQNSDDDEKMQNTDDEErpqLSDDERQQLSEEEKANSDDERPVA 219
Cdd:pfam04147 284 EEEEDGKKKKKHKSADDL-----DDDFVVDDDDDDEEFGLGKGIKERPTATEL---GDEDEDDFIIDDDLVESESDLELD 355

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556695389  220 SDNDDEKQNSDDEEqpqlSDEEKMQNSDDERPQASDEEhrhSDDEEEQDHKSESARGSDSEDEVL 284
Cdd:pfam04147 356 EEEEDEEEEDDEDE----DEEEEEDDDDLSDLESEEDE---EDDEFEEEKKKKKKKDEEGAKEEL 413
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 201-301 2.51e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 44.01  E-value: 2.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 201 RQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDD------EEEQDHKSESA 274
Cdd:COG4547  199 RDLLRDLDLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEgeseaaEAESDEMAEEA 278

                         90       100
                 ....*....|....*....|....*..
gi 556695389 275 RGSDSEDEVLrMKRKNAIASDSEADSD 301
Cdd:COG4547  279 EGEDSEEPGE-PWRPNAPPPDDPADPD 304
 
Name Accession Description Interval E-value
Leo1 pfam04004
Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The ...
 387-476 2.71e-29

Leo1-like protein; Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.


Pssm-ID: 461126  Cd Length: 163  Bit Score: 113.82  E-value: 2.71e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  387 SMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMA 464
Cdd:pfam04004  72 SLSLQLGDEHFDIQSKPLQDDHTYLAARHESSelLQTQGHITEQLTFRPTSTQSDTHRRLTAALAARHKKTGAKIMLIIT 151

                          90
                  ....*....|..
gi 556695389  465 GRDPECQRTEMI 476
Cdd:pfam04004 152 TEDPELEKKEAE 163
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 9-361 6.21e-15

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 78.41  E-value: 6.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   9 GSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSErSDNRS 88
Cdd:NF033609 566 GSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASD-SDSDS 644

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  89 EASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSD-DEER 167
Cdd:NF033609 645 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDS 724

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 168 AQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEkANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSD 247
Cdd:NF033609 725 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 803

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 248 DERPQASDEEhrhSDDEEEQDHKSESARGSDSEDEvlrmkrknaiaSDSEADSDTEVPKDNSGTMDLFGGAD-DISSGSD 326
Cdd:NF033609 804 SDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSESDSNsDSESGSN 869

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 556695389 327 GEDKPP-TPGQPVDENGLPQDQQEEEPIPETRIEVE 361
Cdd:NF033609 870 NNVVPPnSPKNGTNASNKNEAKDSKEPLPDTGSEDE 905
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 1-268 6.06e-11

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 65.79  E-value: 6.06e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389     1 MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFG-DDSEDEGASHHSGSDN 79
Cdd:TIGR00927  627 LGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERkGEQEGEGEIEAKEADH 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    80 HSERSDNRSEASERSDHE-DNDPSDVDQHSGSEapnDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEk 158
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEgTEDEGEIETGEEGE---EVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGE- 782

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   159 IQNSDDEErAQGSDEDKLQNSDDDEKMQNTDDEERpqlSDDERQQLSEEEKANSDDERPVASDNDDEKQNS---DDEEQP 235
Cdd:TIGR00927  783 IQAGEDGE-MKGDEGAEGKVEHEGETEAGEKDEHE---GQSETQADDTEVKDETGEQELNAENQGEAKQDEkgvDGGGGS 858

                          250       260       270
                   ....*....|....*....|....*....|...
gi 556695389   236 QLSDEEKMQNSDDERPQASDEEHRHSDDEEEQD 268
Cdd:TIGR00927  859 DGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 55-328 9.94e-10

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 61.85  E-value: 9.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  55 QPSNKELFGDDSEDEGASHhSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDdEDEGHRSDGGSHHSEAEG 134
Cdd:NF033609 550 EPGEIEPIPEDSDSDPGSD-SGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASD-SDSASDSDSASDSDSASD 627

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 135 SEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEkANSDD 214
Cdd:NF033609 628 SDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDS 706

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 215 ERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEhRHSDDEEEQDHKSESARGSDSEDEVlrmkrknaiAS 294
Cdd:NF033609 707 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDS---------DS 776

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 556695389 295 DSEADSDTEVPKDNSGTMDLFGGAD-DISSGSDGE 328
Cdd:NF033609 777 DSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSD 811
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 31-282 2.69e-09

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 60.39  E-value: 2.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    31 QENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGsDNHSE-------RSDNRSEA---SERSDHEDND 100
Cdd:TIGR00927  632 KGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKG-ENESEgeipaerKGEQEGEGeieAKEADHKGET 710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   101 PSDVDQHSGSEAPNDDEDEGHRSDGGShhSEAEGSEKAHSDDEKWGREDKSDQSDDEkIQNSDDEERAQGSDEDKLQNSD 180
Cdd:TIGR00927  711 EAEEVEHEGETEAEGTEDEGEIETGEE--GEEVEDEGEGEAEGKHEVETEGDRKETE-HEGETEAEGKEDEDEGEIQAGE 787

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   181 DDEkMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDE--KQNSDDEEQPQLSDEEKmqNSDDERPQASDEEH 258
Cdd:TIGR00927  788 DGE-MKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDEtgEQELNAENQGEAKQDEK--GVDGGGGSDGGDSE 864

                          250       260
                   ....*....|....*....|....
gi 556695389   259 RHSDDEEEQDHKSESARGSDSEDE 282
Cdd:TIGR00927  865 EEEEEEEEEEEEEEEEEEEEEEEE 888
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 62-364 3.98e-09

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 59.62  E-value: 3.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    62 FGDDSEDEGAShhsgSDNHSERSDNRSEASERSdhedndPSDVDQHSGSEAPNDDEDEghrsdgGSHHSEAEGSEKAHSD 141
Cdd:TIGR00927  627 LGDLSKGDVAE----AEHTGERTGEEGERPTEA------EGENGEESGGEAEQEGETE------TKGENESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   142 DEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKlQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASD 221
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAE-GTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGE 769

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   222 NDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSES-ARGSDSEDEvlrmkrknAIASDSEADS 300
Cdd:TIGR00927  770 TEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETqADDTEVKDE--------TGEQELNAEN 841

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556695389   301 DTEVPKDNSGtMDLFGGADdissGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPK 364
Cdd:TIGR00927  842 QGEAKQDEKG-VDGGGGSD----GGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPE 900
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 10-235 5.57e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 56.16  E-value: 5.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    10 SDADSEAERKDSDSGSDSDSDQENAASGSnasgSESDQDERGDSGQPSnkelfGDDSEDEGASHHSGSDNHSErSDNRSE 89
Cdd:TIGR00927  681 SEGEIPAERKGEQEGEGEIEAKEADHKGE----TEAEEVEHEGETEAE-----GTEDEGEIETGEEGEEVEDE-GEGEAE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    90 ASERSDHEDNDPSDVDQHSGSEAPNDDEDEG--HRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEER 167
Cdd:TIGR00927  751 GKHEVETEGDRKETEHEGETEAEGKEDEDEGeiQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKD 830

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556695389   168 AQGSDEDKLQNSDD---DEKmqNTDDEERPQLSDDERQQLSEEEKANSDDERpvasdnDDEKQNSDDEEQP 235
Cdd:TIGR00927  831 ETGEQELNAENQGEakqDEK--GVDGGGGSDGGDSEEEEEEEEEEEEEEEEE------EEEEEEEEENEEP 893
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 101-329 2.86e-07

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 53.76  E-value: 2.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 101 PSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSD 180
Cdd:NF033609 558 PEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 637

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 181 DDEKMQNTDDEERPQLSDDERQQLSEeekANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDeehrh 260
Cdd:NF033609 638 SDSDSDSDSDSDSDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD----- 709

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556695389 261 SDDEEEQDHKSESARGSDSEDEvlrmkrknaiaSDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGED 329
Cdd:NF033609 710 SDSDSDSDSDSDSDSDSDSDSD-----------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 767
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 50-284 1.12e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 48.36  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  50 RGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPND-----DEDEGHRSD 124
Cdd:PRK12678  59 RGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAaqareRRERGEAAR 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 125 GGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDklQNSDDDEKMQNTDDEERpqlsddeRQQL 204
Cdd:PRK12678 139 RGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERG--ERGRREERGRDGDDRDR-------RDRR 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 205 SEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSD----SE 280
Cdd:PRK12678 210 EQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNERepelRE 289


                 ....
gi 556695389 281 DEVL 284
Cdd:PRK12678 290 DDVL 293
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 2-184 3.54e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 46.82  E-value: 3.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   2 ADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGS---ESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSD 78
Cdd:PRK12678 123 EAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTeeeERDERRRRGDREDRQAEAERGERGRREERGRDGDD 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  79 NhsERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGShhseaegsekAHSDDEKWGREDKSDQSDDek 158
Cdd:PRK12678 203 R--DRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGD----------RDGDDGEGRGGRRGRRFRD-- 268

                        170       180
                 ....*....|....*....|....*.
gi 556695389 159 iQNSDDEERAQGSDEDKLQNSDDDEK 184
Cdd:PRK12678 269 -RDRRGRRGGDGGNEREPELREDDVL 293
PRK08581 PRK08581
amidase domain-containing protein;
95-279 1.12e-04

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 45.16  E-value: 1.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  95 DHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDED 174
Cdd:PRK08581  28 DDPQKDSTAKTTSHDSKKSNDDETSKDTSSKDTDKADNNNTSNQDNNDKKFSTIDSSTSDSNNIIDFIYKNLPQTNINQL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 175 KLQNSDDDEKMQ------------NTDDEERPQLSD----DERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLS 238
Cdd:PRK08581 108 LTKNKYDDNYSLttliqnlfnlnsDISDYEQPRNSEkstnDSNKNSDSSIKNDTDTQSSKQDKADNQKAPSSNNTKPSTS 187

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 556695389 239 DEEK--MQNSDDERPQASDEEHRHS-DDEEEQDHKSESARGSDS 279
Cdd:PRK08581 188 NKQPnsPKPTQPNQSNSQPASDDTAnQKSSSKDNQSMSDSALDS 231
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 140-284 1.24e-04

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 45.31  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  140 SDDEKWGREDKSDQSDDEkiqnsDDEERAQGSDEDKLQNSDDDEKMQNTDDEErpqLSDDERQQLSEEEKANSDDERPVA 219
Cdd:pfam04147 284 EEEEDGKKKKKHKSADDL-----DDDFVVDDDDDDEEFGLGKGIKERPTATEL---GDEDEDDFIIDDDLVESESDLELD 355

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556695389  220 SDNDDEKQNSDDEEqpqlSDEEKMQNSDDERPQASDEEhrhSDDEEEQDHKSESARGSDSEDEVL 284
Cdd:pfam04147 356 EEEEDEEEEDDEDE----DEEEEEDDDDLSDLESEEDE---EDDEFEEEKKKKKKKDEEGAKEEL 413
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 9-245 2.30e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 44.12  E-value: 2.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   9 GSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASH--HSGSDNHSERSDN 86
Cdd:PRK12678  68 ATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRErgEAARRGAARKAGE 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  87 RSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEE 166
Cdd:PRK12678 148 GGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRR 227

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556695389 167 RAQGsdedklQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERpvasdNDDEKQNSDDEEQPQLSDEEKMQN 245
Cdd:PRK12678 228 GRRR------RRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDR-----RGRRGGDGGNEREPELREDDVLVP 295
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 201-301 2.51e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 44.01  E-value: 2.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 201 RQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDD------EEEQDHKSESA 274
Cdd:COG4547  199 RDLLRDLDLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEgeseaaEAESDEMAEEA 278

                         90       100
                 ....*....|....*....|....*..
gi 556695389 275 RGSDSEDEVLrMKRKNAIASDSEADSD 301
Cdd:COG4547  279 EGEDSEEPGE-PWRPNAPPPDDPADPD 304
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 162-301 2.56e-04

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 44.15  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  162 SDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEE 241
Cdd:pfam04147 283 DEEEEDGKKKKKHKSADDLDDDFVVDDDDDDEEFGLGKGIKERPTATELGDEDEDDFIIDDDLVESESDLELDEEEEDEE 362

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  242 KMQNSDDErpqasdeehrHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSD 301
Cdd:pfam04147 363 EEDDEDED----------EEEEEDDDDLSDLESEEDEEDDEFEEEKKKKKKKDEEGAKEE 412
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 162-351 2.61e-04

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 44.09  E-value: 2.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 162 SDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVA----SDNDDEKQNSDDEEQpql 237
Cdd:PTZ00482  38 VEDIEGPSAVDERTSGVLRDEGKHANILYNSILCNQKKHASFLNQRKSLDDDDDDEFDflyeDDEDDAGNATSGESS--- 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 238 SDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSesargSDSEDEVLRMKRKNAIASDSEADSDteVPKDNSGTMDLFGG 317
Cdd:PTZ00482 115 TDDDSLLELPDRDEDADTQANNDQTNDFDQDDSS-----NSQTDQGLKQSVNLSSAEKLIEEKK--GQTENTFKFYNFGN 187

                        170       180       190
                 ....*....|....*....|....*....|....
gi 556695389 318 ADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEE 351
Cdd:PTZ00482 188 DGEEAAAKDGGKSKSSDPGPLNDSDGQGDDGDPE 221
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 62-195 3.70e-04

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 43.70  E-value: 3.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  62 FGDDSEDEgasHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSD 141
Cdd:PTZ00482  94 FDFLYEDD---EDDAGNATSGESSTDDDSLLELPDRDEDADTQANNDQTNDFDQDDSSNSQTDQGLKQSVNLSSAEKLIE 170

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 556695389 142 DEKWGRED---KSDQSDDEKIQNSDDEERAQGSDEDKLqNSDDDEKMQNTDDEERPQ 195
Cdd:PTZ00482 171 EKKGQTENtfkFYNFGNDGEEAAAKDGGKSKSSDPGPL-NDSDGQGDDGDPESAEED 226
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 13-185 4.93e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.45  E-value: 4.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    13 DSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQpsnKELFGDDSEDEGASHHSGSDNHSersdNRSEASE 92
Cdd:TIGR00927  727 EDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGE---TEAEGKEDEDEGEIQAGEDGEMK----GDEGAEG 799

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389    93 RSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSD--QSDDEKIQNSDDEERAQG 170
Cdd:TIGR00927  800 KVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDggDSEEEEEEEEEEEEEEEE 879

                          170
                   ....*....|....*
gi 556695389   171 SDEDKLQNSDDDEKM 185
Cdd:TIGR00927  880 EEEEEEEEEENEEPL 894
rne PRK10811
ribonuclease E; Reviewed
 55-267 5.29e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 43.10  E-value: 5.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   55 QPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDvDQHSGSEAPNDDEDEGHRSDggshhsEAEG 134
Cdd:PRK10811  589 QEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRDNRTRREGRENRE-ENRRNRRQAQQQTAETRESQ------QAEV 661

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  135 SEKAHSDDEKwGREDKSDQsddekiQNSDDEERAQGSDEDKLQNSDDDEKmQNTDDEERPQLSDDERQ--QLSEE---EK 209
Cdd:PRK10811  662 TEKARTQDEQ-QQAPRRER------QRRRNDEKRQAQQEAKALNVEEQSV-QETEQEERVQQVQPRRKqrQLNQKvriEQ 733

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 556695389  210 ANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQ 267
Cdd:PRK10811  734 SVAEEAVAPVVEETVAAEPVVQEVPAPRTELVKVPLPVVAQTAPEQDEENNAENRDNN 791
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 146-266 7.10e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 42.47  E-value: 7.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 146 GREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEkmqntdDEERPQLSDDERQQLSEEEKANSDDErpvasdnDDE 225
Cdd:COG4547  210 ELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGA------EAEDAEASGDDAEEGESEAAEAESDE-------MAE 276

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 556695389 226 KQNSDDEEQPQLSDEEKMQNSDDERP-------QASDEEHRHSD--DEEE 266
Cdd:COG4547  277 EAEGEDSEEPGEPWRPNAPPPDDPADpdykvftTAFDEVVAAEDlcDPEE 326
PHA03169 PHA03169
hypothetical protein; Provisional
 63-259 7.19e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 42.27  E-value: 7.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  63 GDDSEDEGASHHSGSDNHSERSDNRSEASERSDH-------EDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGS 135
Cdd:PHA03169  48 PPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHgekeergQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSS 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 136 EKAHSDDEKWGRE-------DKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERqqlSEEE 208
Cdd:PHA03169 128 PESPASHSPPPSPpshpgphEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTS---SPPP 204

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 556695389 209 KANSDDERPVASDNDDEKQNSDDEEQPQLSDEEkmqnSDDERPQASDEEHR 259
Cdd:PHA03169 205 QSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEP----TEPEREGPPFPGHR 251
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 141-305 9.39e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 42.47  E-value: 9.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  141 DDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKL-------QNSDDDEKMQNTDDEERPQlsddERQQLSEEEKANSD 213
Cdd:PTZ00341  418 DLEKQKYMDMLDGSEDESVEDNEEEHSGDANEEELSvdehveeHNADDSGEQQSDDESGEHQ----SVNEIVEEQSVNEH 493

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  214 DERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQAS-DEEHRHSDDEEEQDHKSESArgsdsedevlrmkrkNAI 292
Cdd:PTZ00341  494 VEEPTVADIVEQETVDEHVEEPAVDENEEQQTADEHVEEPTiAEEHVEEEISTAEEHIEEPA---------------SDV 558

                         170
                  ....*....|...
gi 556695389  293 ASDSEADSDTEVP 305
Cdd:PTZ00341  559 QQDSEAAPTIEIP 571
PHA02664 PHA02664
hypothetical protein; Provisional
 31-168 2.23e-03

hypothetical protein; Provisional


Pssm-ID: 177447  Cd Length: 534  Bit Score: 40.75  E-value: 2.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  31 QENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHhSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGS 110
Cdd:PHA02664 380 EVIAAGAAAAMIAAAERAANGARGSPMAAPEEGRAAAAAAAAN-APADQDVEAEAHDEFDQDPGAPAHADRADSDEDDMD 458

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556695389 111 EAPNDDEDEGHRSDGGSHHSEA--EGSEKAHSDDEKWGREDKSDQSDD-----EKIQNSDDEERA 168
Cdd:PHA02664 459 EQESGDERADGEDDSDSSYSYSttSSEDESDSADDSWGDESDSGIEHDdggvgQAIEEEEEEERA 523
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 77-243 2.37e-03

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 41.00  E-value: 2.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  77 SDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEK-WGREDKSDQSD 155
Cdd:PTZ00482  73 QKKHASFLNQRKSLDDDDDDEFDFLYEDDEDDAGNATSGESSTDDDSLLELPDRDEDADTQANNDQTNdFDQDDSSNSQT 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 156 DEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDeerpqlsDDERQQLSEEEKANSDDERPVASDND--DEKQNSDDEE 233
Cdd:PTZ00482 153 DQGLKQSVNLSSAEKLIEEKKGQTENTFKFYNFGN-------DGEEAAAKDGGKSKSSDPGPLNDSDGqgDDGDPESAEE 225

                        170
                 ....*....|
gi 556695389 234 QPQLSDEEKM 243
Cdd:PTZ00482 226 DKAASNTRAA 235
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 164-270 2.65e-03

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 40.55  E-value: 2.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 164 DEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDErpvasDNDDEKQNSDDEEQPQLSDEEKM 243
Cdd:COG4547  206 DLAEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGD-----DAEEGESEAAEAESDEMAEEAEG 280

                         90       100
                 ....*....|....*....|....*..
gi 556695389 244 QNSDDErPQASDEEHRHSDDEEEQDHK 270
Cdd:COG4547  281 EDSEEP-GEPWRPNAPPPDDPADPDYK 306
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 80-282 3.99e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 40.41  E-value: 3.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389   80 HSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKI 159
Cdd:PTZ00108 1166 ASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKS 1245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  160 QNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERP-QLSDDERQQLSEEEKANSDDERPVASDNDD--------EKQNSD 230
Cdd:PTZ00108 1246 KKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAvQYSPPPPSKRPDGESNGGSKPSSPTKKKVKkrlegslaALKKKK 1325

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 556695389  231 DEEQPQL----SDEEKMQNSD-DERPQASDEEHRHSDDEEEQDHKSESARGSDSEDE 282
Cdd:PTZ00108 1326 KSEKKTArkkkSKTRVKQASAsQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDE 1382
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 131-228 4.40e-03

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 40.16  E-value: 4.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 131 EAEGSEKAHSDDEKwgREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKA 210
Cdd:COG4547  209 EELGEDEDEEDEDD--EDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEGESEAAEAESDEMAEEAEGEDSEEP 286

                         90
                 ....*....|....*...
gi 556695389 211 NSDDERPVASDNDDEKQN 228
Cdd:COG4547  287 GEPWRPNAPPPDDPADPD 304
COG5593 COG5593
Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal ...
 149-272 5.35e-03

Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227880 [Multi-domain]  Cd Length: 821  Bit Score: 40.02  E-value: 5.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 149 DKSDQSDDEKIQNSDDEERAQ---GSDEDKLQNSDDDEKMQNTDDEERPQLSDDErqQLSEEEKANSDDErpvasDNDDE 225
Cdd:COG5593  680 DSDDEMDENEIWSALVKSRPDvedDSDDSELDFAEDDFSDSTSDDEPKLDAIDDE--DAKSEGSQESDQE-----EGLDE 752

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 556695389 226 KQNSDDEEQPQlSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSE 272
Cdd:COG5593  753 IFYSFDGEQDN-SDSFAESSEEDESSEEEKEEEENKEVSAKRAKKKQ 798
TFIIF_alpha pfam05793
Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); Transcription initiation ...
 111-312 5.58e-03

Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II.


Pssm-ID: 310411 [Multi-domain]  Cd Length: 528  Bit Score: 39.55  E-value: 5.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  111 EAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDklqnSDDDEKMQNTDD 190
Cdd:pfam05793 191 AFGEHDEETEGEKGGGGRGKDLKIKDLEGDDEDDGDESDKGGEDGDEEKKKKKKKKLAKNKKKL----DDDKKKKRGGDD 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  191 EERPQLSDDerqqlseeekaNSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDErpQASDEEHRHSDDEEEQDHK 270
Cdd:pfam05793 267 DAFEYDSDD-----------GDDEGREEDYISDSSASGNDPEEREDKLSPEEPAKGEIE--QSDDSEESEEEKNEEEGKL 333

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 556695389  271 SESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTM 312
Cdd:pfam05793 334 SKKGKKAKKLKGKKNGKDKSESSDGDDSDDSDIDDEDSVPLF 375
PHA03169 PHA03169
hypothetical protein; Provisional
 15-200 6.99e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 39.18  E-value: 6.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  15 EAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKElfGDDSEDEGASHHSGSDNHSERSDNRSEASERS 94
Cdd:PHA03169  64 QGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSG--SAEELASGLSPENTSGSSPESPASHSPPPSPP 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  95 DHEDnDPSDVDQHSGSEAPNDDEDEGhrsDGGSHHSEAEGSEKAHSDDEKWGRE--DKSDQSDDEKIQNSDDEERAQGSD 172
Cdd:PHA03169 142 SHPG-PHEPAPPESHNPSPNQQPSSF---LQPSHEDSPEEPEPPTSEPEPDSPGppQSETPTSSPPPQSPPDEPGEPQSP 217

                        170       180
                 ....*....|....*....|....*....
gi 556695389 173 E-DKLQNSDDDEKMQNTDDEERPQLSDDE 200
Cdd:PHA03169 218 TpQQAPSPNTQQAVEHEDEPTEPEREGPP 246
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 130-267 7.06e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 39.53  E-value: 7.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  130 SEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEEraQGSDEDklqnsDDDEKMQNTDDEERPQLsddeRQQLSEEEK 209
Cdd:pfam04931 628 NPEGQQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDD--DEDDDD-----EDEEDDDDEDVDEIDEL----RAKLAEALG 696

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556695389  210 ANSDDErpvasDNDDEkqnSDDEEQpqlsDEEKMQNSDD-------ERPQASDEEHRHSDDEEEQ 267
Cdd:pfam04931 697 EHGDDA-----DDDDS---DSDEDM----DDEQMMALDEqlaeifkERKKAGNDKKKKKKDAKEN 749
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 34-184 7.84e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 39.19  E-value: 7.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  34 AASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSgSEAP 113
Cdd:PRK13108 309 ASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGDLAGQA-PAAH 387

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556695389 114 NDDEDEGHRSDGGSHHSEAE---GSEKAHSDDEkwgrEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEK 184
Cdd:PRK13108 388 QVDAEAASAAPEEPAALASEahdETEPEVPEKA----APIPDPAKPDELAVAGPGDDPAEPDGIRRQDDFSSRR 457
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 111-249 9.22e-03

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 39.14  E-value: 9.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389  111 EAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDD 190
Cdd:pfam04147 281 EEDEEEEDGKKKKKHKSADDLDDDFVVDDDDDDEEFGLGKGIKERPTATELGDEDEDDFIIDDDLVESESDLELDEEEED 360

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 556695389  191 EErpqlSDDErqqlSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDE 249
Cdd:pfam04147 361 EE----EEDD----EDEDEEEEEDDDDLSDLESEEDEEDDEFEEEKKKKKKKDEEGAKE 411
COG5593 COG5593
Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal ...
 119-259 9.65e-03

Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227880 [Multi-domain]  Cd Length: 821  Bit Score: 38.87  E-value: 9.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695389 119 EGHRSDGGSHHSEAEGSEkahsdDEKW-----GREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNtddEER 193
Cdd:COG5593  670 KGKKSNKASFDSDDEMDE-----NEIWsalvkSRPDVEDDSDDSELDFAEDDFSDSTSDDEPKLDAIDDEDAKS---EGS 741

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556695389 194 PQLSDDErqqlSEEEKANSDDERpvaSDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHR 259
Cdd:COG5593  742 QESDQEE----GLDEIFYSFDGE---QDNSDSFAESSEEDESSEEEKEEEENKEVSAKRAKKKQRK 800
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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