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Conserved domains on  [gi|574288369|ref|NP_001276045|]
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sex hormone-binding globulin isoform 7 [Homo sapiens]

Protein Classification

LamG domain-containing protein( domain architecture ID 366259)

LamG (Laminin G) domain-containing protein may serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LamG super family cl22861
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 34-89 3.07e-05

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


The actual alignment was detected with superfamily member pfam00054:

Pssm-ID: 473984 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 3.07e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 574288369   34 VLRLRQVSGPLTskrHPIMRIALGGLLFP---ASNLRLPLVPALDGCLRRDSWLDKQAE 89
Cdd:pfam00054  76 RPTGESPLGATT---DLDVDGPLYVGGLPslgVKKRRLAISPSFDGCIRDVIVNGKPLD 131
 
Name Accession Description Interval E-value
Laminin_G_1 pfam00054
Laminin G domain;
34-89 3.07e-05

Laminin G domain;


Pssm-ID: 395008 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 3.07e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 574288369   34 VLRLRQVSGPLTskrHPIMRIALGGLLFP---ASNLRLPLVPALDGCLRRDSWLDKQAE 89
Cdd:pfam00054  76 RPTGESPLGATT---DLDVDGPLYVGGLPslgVKKRRLAISPSFDGCIRDVIVNGKPLD 131
 
Name Accession Description Interval E-value
Laminin_G_1 pfam00054
Laminin G domain;
34-89 3.07e-05

Laminin G domain;


Pssm-ID: 395008 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 3.07e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 574288369   34 VLRLRQVSGPLTskrHPIMRIALGGLLFP---ASNLRLPLVPALDGCLRRDSWLDKQAE 89
Cdd:pfam00054  76 RPTGESPLGATT---DLDVDGPLYVGGLPslgVKKRRLAISPSFDGCIRDVIVNGKPLD 131
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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