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Conserved domains on  [gi|584277111|ref|NP_001276868|]
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excitatory amino acid transporter 1 isoform 4 [Homo sapiens]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
53-450 4.09e-106

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 322.06  E-value: 4.09e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  53 LTVTAVIVGMAAL-DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADaFLDLIRNM 131
Cdd:COG1301   49 LVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNI 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 132 FPPNLVEAcfkqfktnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgSVNGvNALGLVVFSMCFGFVI 211
Cdd:COG1301  128 IPSNIFEA---------------------------------------------------FAEG-NMLQIIFFAILFGIAL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 212 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMeDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLY 291
Cdd:COG1301  156 AALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLIL 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 292 FLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVN 371
Cdd:COG1301  234 RLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAY 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277111 372 NFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 450
Cdd:COG1301  314 GIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
53-450 4.09e-106

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 322.06  E-value: 4.09e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  53 LTVTAVIVGMAAL-DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADaFLDLIRNM 131
Cdd:COG1301   49 LVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNI 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 132 FPPNLVEAcfkqfktnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgSVNGvNALGLVVFSMCFGFVI 211
Cdd:COG1301  128 IPSNIFEA---------------------------------------------------FAEG-NMLQIIFFAILFGIAL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 212 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMeDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLY 291
Cdd:COG1301  156 AALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLIL 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 292 FLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVN 371
Cdd:COG1301  234 RLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAY 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277111 372 NFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 450
Cdd:COG1301  314 GIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
45-451 2.96e-102

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 311.76  E-value: 2.96e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111   45 LFRNAFVLLTVTAVIVGMAAL-DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKeNMHREGKIVRVTAADA 123
Cdd:pfam00375  36 LLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPS 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  124 FLDLIRNMFPPNLVEACFKQfktnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgsvngvNALGLVVF 203
Cdd:pfam00375 115 LLDFILNIIPSNIFEALAEG----------------------------------------------------NVLAVIVF 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  204 SMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEmEDMGVIGgQLAMYTVTVIVGLLIHA 283
Cdd:pfam00375 143 AILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHL 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  284 VIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALA 363
Cdd:pfam00375 221 LIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVA 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  364 AIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSL 443
Cdd:pfam00375 301 AIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAA 380

                  ....*...
gi 584277111  444 GAGIVEHL 451
Cdd:pfam00375 381 AAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
188-440 1.12e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 129.25  E-value: 1.12e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 188 VPGSVNGVNALG----LVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIvemedmGV 263
Cdd:PRK01663 137 IPTTVVGAFASGdilqVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTI------GK 210
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 264 IG----GQLAMYTVTVIVGLLIHAVIVLPLlyflVTRK---NPWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGV 336
Cdd:PRK01663 211 YGvgslVQLGQLIGCFYITCILFVFVVLGA----IARLtgfSIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGC 285
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 337 DKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LP 415
Cdd:PRK01663 286 KKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIP 365
                        250       260
                 ....*....|....*....|....*
gi 584277111 416 TDDITLIIAVDWFLDRLRTTTNVLG 440
Cdd:PRK01663 366 VAGLALILGIDRFMSEARALTNLIG 390
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
53-450 4.09e-106

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 322.06  E-value: 4.09e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  53 LTVTAVIVGMAAL-DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADaFLDLIRNM 131
Cdd:COG1301   49 LVFFSIVVGIASLgDLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNI 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 132 FPPNLVEAcfkqfktnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgSVNGvNALGLVVFSMCFGFVI 211
Cdd:COG1301  128 IPSNIFEA---------------------------------------------------FAEG-NMLQIIFFAILFGIAL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 212 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMeDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLY 291
Cdd:COG1301  156 AALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLIL 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 292 FLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVN 371
Cdd:COG1301  234 RLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAY 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277111 372 NFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 450
Cdd:COG1301  314 GIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
45-451 2.96e-102

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 311.76  E-value: 2.96e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111   45 LFRNAFVLLTVTAVIVGMAAL-DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKeNMHREGKIVRVTAADA 123
Cdd:pfam00375  36 LLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPS 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  124 FLDLIRNMFPPNLVEACFKQfktnyekrsfkvpiqanetlvgavinnvseametltriteelvpvpgsvngvNALGLVVF 203
Cdd:pfam00375 115 LLDFILNIIPSNIFEALAEG----------------------------------------------------NVLAVIVF 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  204 SMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEmEDMGVIGgQLAMYTVTVIVGLLIHA 283
Cdd:pfam00375 143 AILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHL 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  284 VIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALA 363
Cdd:pfam00375 221 LIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVA 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  364 AIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSL 443
Cdd:pfam00375 301 AIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAA 380

                  ....*...
gi 584277111  444 GAGIVEHL 451
Cdd:pfam00375 381 AAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
188-440 1.12e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 129.25  E-value: 1.12e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 188 VPGSVNGVNALG----LVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIvemedmGV 263
Cdd:PRK01663 137 IPTTVVGAFASGdilqVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTI------GK 210
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 264 IG----GQLAMYTVTVIVGLLIHAVIVLPLlyflVTRK---NPWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGV 336
Cdd:PRK01663 211 YGvgslVQLGQLIGCFYITCILFVFVVLGA----IARLtgfSIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGC 285
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 337 DKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LP 415
Cdd:PRK01663 286 KKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIP 365
                        250       260
                 ....*....|....*....|....*
gi 584277111 416 TDDITLIIAVDWFLDRLRTTTNVLG 440
Cdd:PRK01663 366 VAGLALILGIDRFMSEARALTNLIG 390
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
51-443 2.04e-30

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 122.95  E-value: 2.04e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111  51 VLLTVTAVIVGMAAL-DSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMhregkivrVTAADAfldlir 129
Cdd:PRK11283  57 VPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQ--------LATVDI------ 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 130 nmfppnlveacfkqfkTNYEKRSFKVPIQAN---ETLVGAVINNVSEAMETltritEELVPVpgsvngvnalglVVFSMC 206
Cdd:PRK11283 123 ----------------SKYQSTTEEVQSHSHglmGTILSLIPTNIFASMAK-----GEMLPI------------IFFSVL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 207 FGFVIGNM-KEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIggQLAMYTVTVIVGLLIHAVI 285
Cdd:PRK11283 170 FGLGLSSLpATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVYFAILFFALV 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 286 VLPLLYFLVtRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENnGVDKRVTRFVLPVGATINMDGTALYEALAAI 365
Cdd:PRK11283 248 VLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAY-GAPKSITSFVVPTGYSFNLDGSTLYQSIAAI 325
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584277111 366 FIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSL 443
Cdd:PRK11283 326 FIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNAL 403
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
196-441 4.01e-30

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 121.70  E-value: 4.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 196 NALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIA---GK--IVEMEDMGVIggqLAM 270
Cdd:PRK13027 149 DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAfttGKygVGSLKQLGML---VAV 225
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 271 YTVTVIVGLLIHAVIVLPLLYFLVtrknpWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGVDKRVTRFVLPVGAT 350
Cdd:PRK13027 226 FYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLREELLIVLGTASSDAVLPQVMRKLE-HMGIKDSTVGLVIPTGYS 299
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 351 INMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTDDITLIIAVDWFL 429
Cdd:PRK13027 300 FNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFM 379
                        250
                 ....*....|..
gi 584277111 430 DRLRTTTNVLGD 441
Cdd:PRK13027 380 GIARALTNLIGN 391
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
152-450 1.73e-16

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 80.48  E-value: 1.73e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 152 SFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVP-GSVNGVNALGLVVFSMCFGFVignMKEQGQALREFFDSLNE 230
Cdd:PRK14695  15 SFIVPIEITLNSANTEIAPPDGIGQVLSNLLLKLVDSPvNALLTANYIGILSWAVIFGIA---MREASKNSKELLKTIAD 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 231 AIMRLVAVIMWYAPVGILFLIAGKIvemEDMGVigGQLAMY---TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLL 307
Cdd:PRK14695  92 VTSKIVEWIINLAPFGILGLVFKTI---SDKGV--GSLANYgilLVLLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCL 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 308 Q-ALITALGTSSSSATLPITFKcLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISIT 386
Cdd:PRK14695 167 RvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVV 245
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 584277111 387 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFL----DRLRTTTNVLGDSLGAGIVEH 450
Cdd:PRK14695 246 AAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDSCETALNSSTDVLFTAVAEY 313
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
193-397 8.74e-16

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 79.14  E-value: 8.74e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 193 NGVNAL------GLVVFSMCFGFVignMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIG- 265
Cdd:PRK13628 137 NPINALlnanyiGILAWAIGLGLA---LRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAGy 213
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 266 GQLAMytvtVIVG-LLIHAVIVLPLLYFLVTRKNPW--VFIgGLLQALITALGTSSSSATLPITFKcLEENNGVDKRVTR 342
Cdd:PRK13628 214 AQLLA----VLVGcMLFVALVVNPLIVFWKIRRNPYplVFT-CLRESGVTAFFTRSSAANIPVNMA-LCEKLGLDEDTYS 287
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 584277111 343 FVLPVGATINMDGtalyealAAIFI-----AQVNNF--ELNFGQIITISITATAASIGAAGI 397
Cdd:PRK13628 288 VSIPLGATINMAG-------AAITItvltlAAVHTLgiPVDLPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
187-398 1.05e-14

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 75.98  E-value: 1.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 187 PVPGSVNGvNALGLVVFSMCFGFVignMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMedmGVigG 266
Cdd:COG3633  137 PVNALANA-NYIGILAWAIGLGLA---LRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATT---GF--S 207
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 267 QLAMYT--VTVIVG-LLIHAVIVLPLLYFLVTRKNPW--VFIGgLLQALITALGTSSSSATLPITFKcLEENNGVDKRVT 341
Cdd:COG3633  208 ALLGYAhlLAVLVGcMLFVALVVNPLIVFLKIRRNPYplVFTC-LRESGITAFFTRSSAANIPVNMA-LCEKLGLDEDTY 285
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 584277111 342 RFVLPVGATINMDGtalyealAAIFI-----AQVN--NFELNFGQIITISITATAASIGAAGIP 398
Cdd:COG3633  286 SVSIPLGATINMAG-------AAITItvltlAAVHtlGIEVDLPTALLLSVVAAVSACGASGVA 342
AglD2 COG0392
Predicted membrane flippase AglD2/YbhN, UPF0104 family [Cell wall/membrane/envelope biogenesis] ...
260-429 5.83e-03

Predicted membrane flippase AglD2/YbhN, UPF0104 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440161  Cd Length: 289  Bit Score: 38.78  E-value: 5.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 260 DMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNP-------WVFIGGLLQALITALGTSSSSATLPITFKCLEE 332
Cdd:COG0392   77 PAGKAAAIVALERLTDLLGLLLLAGLGLLFGPGALPGLGNlpgalllLLLGLALLAAVLLYLLLLAFRPRLLLRLRRWKL 156
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277111 333 NNGVDKRVTRFVLPVGATINMDGTALY-----------EALAAIFIAQVNNFELNFGQIITISITATAASIgAAGIPqAG 401
Cdd:COG0392  157 LRKIREKLERFLEGLRRLRLSPRLLLLqlllslldwllAALILYFLLPALGVDVSFLAVLAVFLLASLAGL-LPPTP-GG 234
                        170       180       190
                 ....*....|....*....|....*....|..
gi 584277111 402 L----VTMVIVLTSVGLPTDDITLIIAVDWFL 429
Cdd:COG0392  235 LgvfeAALLLLLSLFGVPAAAALAALLLYRLI 266
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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