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Conserved domains on  [gi|584277046|ref|NP_001276872|]
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excitatory amino acid transporter 1 isoform 4 [Rattus norvegicus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
46-384 1.59e-96

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 295.10  E-value: 1.59e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  46 FRNAFVLLTVSAVIVGTILGFALRPYkmsyrEVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAV 124
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPEL-----VAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 125 VYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYR-----------------------------EGKIVQV----------- 164
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADaaaaeaaeapslldfllniipsnifeafaEGNMLQIiffailfgial 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 165 ----TAADAFLDLI---------------RYAPLGILFLIAGKIVEMeDMGVIgGQLAMYTVTVIVGLLIHAVIVLPLLY 225
Cdd:COG1301  156 aalgEKGKPLLDFFeslsevmfkivgwvmKLAPIGVFALIAATVAKY-GLDAL-GSLGKLVLTVYLALLLHLFVVLPLIL 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 226 FLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVN 305
Cdd:COG1301  234 RLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAY 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277046 306 NFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 384
Cdd:COG1301  314 GIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
46-384 1.59e-96

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 295.10  E-value: 1.59e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  46 FRNAFVLLTVSAVIVGTILGFALRPYkmsyrEVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAV 124
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPEL-----VAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 125 VYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYR-----------------------------EGKIVQV----------- 164
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADaaaaeaaeapslldfllniipsnifeafaEGNMLQIiffailfgial 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 165 ----TAADAFLDLI---------------RYAPLGILFLIAGKIVEMeDMGVIgGQLAMYTVTVIVGLLIHAVIVLPLLY 225
Cdd:COG1301  156 aalgEKGKPLLDFFeslsevmfkivgwvmKLAPIGVFALIAATVAKY-GLDAL-GSLGKLVLTVYLALLLHLFVVLPLIL 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 226 FLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVN 305
Cdd:COG1301  234 RLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAY 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277046 306 NFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 384
Cdd:COG1301  314 GIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
50-385 9.08e-91

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 279.79  E-value: 9.08e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046   50 FVLLTVSAVIVGTILGFALRPYKMsyrevkYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAVVYYM 128
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  129 TTTIIAVVIGIIIVIIIHPGKGTKENMyREGKIVQVTAADAFLDLI---------------------------------- 174
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLALIA-ASLKEAKAAEAPSLLDFIlniipsnifealaegnvlavivfailfgialaal 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  175 --------------------------RYAPLGILFLIAGKIVEmEDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLV 228
Cdd:pfam00375 154 gekgepllnfieslqevmmkvigwvmKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFL 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  229 TRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFD 308
Cdd:pfam00375 232 GKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVD 311
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 584277046  309 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL 385
Cdd:pfam00375 312 LSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
57-377 3.47e-30

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 121.02  E-value: 3.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  57 AVIVGTILGFALRpYKMSYRE---VKYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAVVYYMTTTI 132
Cdd:PRK11283  15 ALVLGILLGAYLH-YHSDSRDwlvSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITT 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 133 IAVVIGIIIVIIIHPGKGTKENMYREGKI--VQVTAAD----------AFLDLI-------------------------- 174
Cdd:PRK11283  94 VAIILGITLANVFQPGAGIDMSQLATVDIskYQSTTEEvqshshglmgTILSLIptnifasmakgemlpiiffsvlfglg 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 175 -------------------------------RYAPLGILFLIAGKIVEMEDMGVIggQLAMYTVTVIVGLLIHAVIVLPL 223
Cdd:PRK11283 174 lsslpathreplvtvfrsvsetmfkvthmvmRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVYFAILFFALVVLGI 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 224 LYFLVtRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENnGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQ 303
Cdd:PRK11283 252 VARLC-GLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAY-GAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQ 329
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 584277046 304 VNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSL 377
Cdd:PRK11283 330 LYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNAL 403
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
46-384 1.59e-96

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 295.10  E-value: 1.59e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  46 FRNAFVLLTVSAVIVGTILGFALRPYkmsyrEVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAV 124
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPEL-----VAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 125 VYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYR-----------------------------EGKIVQV----------- 164
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADaaaaeaaeapslldfllniipsnifeafaEGNMLQIiffailfgial 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 165 ----TAADAFLDLI---------------RYAPLGILFLIAGKIVEMeDMGVIgGQLAMYTVTVIVGLLIHAVIVLPLLY 225
Cdd:COG1301  156 aalgEKGKPLLDFFeslsevmfkivgwvmKLAPIGVFALIAATVAKY-GLDAL-GSLGKLVLTVYLALLLHLFVVLPLIL 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 226 FLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVN 305
Cdd:COG1301  234 RLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAY 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 584277046 306 NFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEH 384
Cdd:COG1301  314 GIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
50-385 9.08e-91

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 279.79  E-value: 9.08e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046   50 FVLLTVSAVIVGTILGFALRPYKMsyrevkYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAVVYYM 128
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  129 TTTIIAVVIGIIIVIIIHPGKGTKENMyREGKIVQVTAADAFLDLI---------------------------------- 174
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLALIA-ASLKEAKAAEAPSLLDFIlniipsnifealaegnvlavivfailfgialaal 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  175 --------------------------RYAPLGILFLIAGKIVEmEDMGVIGgQLAMYTVTVIVGLLIHAVIVLPLLYFLV 228
Cdd:pfam00375 154 gekgepllnfieslqevmmkvigwvmKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFL 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  229 TRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFD 308
Cdd:pfam00375 232 GKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVD 311
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 584277046  309 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL 385
Cdd:pfam00375 312 LSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
57-377 3.47e-30

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 121.02  E-value: 3.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  57 AVIVGTILGFALRpYKMSYRE---VKYFSFPGELLMRMLQMLVLPLIISSLVTGMAAL-DSKASGKMGMRAVVYYMTTTI 132
Cdd:PRK11283  15 ALVLGILLGAYLH-YHSDSRDwlvSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITT 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 133 IAVVIGIIIVIIIHPGKGTKENMYREGKI--VQVTAAD----------AFLDLI-------------------------- 174
Cdd:PRK11283  94 VAIILGITLANVFQPGAGIDMSQLATVDIskYQSTTEEvqshshglmgTILSLIptnifasmakgemlpiiffsvlfglg 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 175 -------------------------------RYAPLGILFLIAGKIVEMEDMGVIggQLAMYTVTVIVGLLIHAVIVLPL 223
Cdd:PRK11283 174 lsslpathreplvtvfrsvsetmfkvthmvmRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVYFAILFFALVVLGI 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 224 LYFLVtRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENnGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQ 303
Cdd:PRK11283 252 VARLC-GLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAY-GAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQ 329
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 584277046 304 VNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSL 377
Cdd:PRK11283 330 LYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNAL 403
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
42-375 1.81e-28

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 115.92  E-value: 1.81e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  42 KSYLFRNAFVLLtVSAVIVGTILGFALRPYKMSYREVkyfsfpGELLMRMLQMLVLPLIISSLVTGMA-ALDSKASGKMG 120
Cdd:PRK13027   1 MKKFLRSLFGQV-VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAgAGDLKKVGRVG 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 121 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKG----------------TKENMYREG------KIVQVTAADAF-------- 170
Cdd:PRK13027  74 LKAVIYFEVMTTIALVIGLVLAYLTGPGVGmnidlrsldaaslagyAKNAQSLKGtagfllKLIPTTAVDAFakgdilqv 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 171 ----------LDLI--RYAPLG--------ILFLIAGKIVEMEDMGVIGG--------------QLAMYTVTVIVGLLIH 216
Cdd:PRK13027 154 llfsvlfgsaLSLLgeRAKRVNrlidelshVLFRIMGFIIKLAPLGVLGAiafttgkygvgslkQLGMLVAVFYLTCFVF 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 217 AVIVLPLLYFLvTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGVDKRITRFVLPVGATINMDGTALYEAL 296
Cdd:PRK13027 234 VVVVLGAVMRL-AGFSVFKLIRYLREELLIVLGTASSDAVLPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTL 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 297 AAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTDDITLIIAVDWFLDRLRTTTNVLGD 375
Cdd:PRK13027 312 AAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGN 391
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
42-374 4.00e-26

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 109.61  E-value: 4.00e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  42 KSYLFRNAFVLLtVSAVIVGTILGF-------ALRPYkmsyrevkyfsfpGELLMRMLQMLVLPLIISSLVTGMAAL-DS 113
Cdd:PRK01663   2 KKPLYKSLYFQV-LVAIIIGILLGHfypelgaQMKPL-------------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDM 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 114 KASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKG---------TKE-NMYREG-----------KIVQVTAADAF-- 170
Cdd:PRK01663  68 KKVGRVGGKALLYFEIVSTIALIIGLIVVNVVQPGAGmnidpatldAKAvAQYAAQaheqgtvdflmDIIPTTVVGAFas 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 171 ---LDLIRYAPL-----------------------GILFLIAGKIVEMEDMGVIGG--------------QLAMYTVTVI 210
Cdd:PRK01663 148 gdiLQVLLFAVLfgfalarlgekgkpvfdfieslsHVLFGIVNMIMKLAPIGAFGAmaftigkygvgslvQLGQLIGCFY 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 211 VGLLIHAVIVLPLlyflVTRK---NPWVFIGGLLQALITALGTSSSSATLPITFKCLEeNNGVDKRITRFVLPVGATINM 287
Cdd:PRK01663 228 ITCILFVFVVLGA----IARLtgfSIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNL 302
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 288 DGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTDDITLIIAVDWFLDRL 366
Cdd:PRK01663 303 DGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEA 382

                 ....*...
gi 584277046 367 RTTTNVLG 374
Cdd:PRK01663 383 RALTNLIG 390
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
174-332 1.16e-12

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 69.04  E-value: 1.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 174 IRYAPLGILFLIAGKIVEMedmGVigGQLAMYT--VTVIVG-LLIHAVIVLPLLYFLVTRKNPW--VFIGgLLQALITAL 248
Cdd:COG3633  186 IRFAPLGIFGLVASTVATT---GF--SALLGYAhlLAVLVGcMLFVALVVNPLIVFLKIRRNPYplVFTC-LRESGITAF 259
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 249 GTSSSSATLPITFKcLEENNGVDKRITRFVLPVGATINMDGtalyealAAIFI-----AQVN--NFDLNFGQIITISITA 321
Cdd:COG3633  260 FTRSSAANIPVNMA-LCEKLGLDEDTYSVSIPLGATINMAG-------AAITItvltlAAVHtlGIEVDLPTALLLSVVA 331
                        170
                 ....*....|.
gi 584277046 322 TAASIGAAGIP 332
Cdd:COG3633  332 AVSACGASGVA 342
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
174-331 1.33e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 68.74  E-value: 1.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 174 IRYAPLGILFLIAGKIVEMEDMGVIG-GQLAMytvtVIVG-LLIHAVIVLPLLYFLVTRKNPW--VFIgGLLQALITALG 249
Cdd:PRK13628 187 IRFAPIGIFGLVASTLAETGFSALAGyAQLLA----VLVGcMLFVALVVNPLIVFWKIRRNPYplVFT-CLRESGVTAFF 261
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 250 TSSSSATLPITFKcLEENNGVDKRITRFVLPVGATINMDGtalyealAAIFI-----AQVNNFDL--NFGQIITISITAT 322
Cdd:PRK13628 262 TRSSAANIPVNMA-LCEKLGLDEDTYSVSIPLGATINMAG-------AAITItvltlAAVHTLGIpvDLPTALLLSVVAA 333

                 ....*....
gi 584277046 323 AASIGAAGI 331
Cdd:PRK13628 334 ISACGASGV 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
173-384 2.11e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 67.77  E-value: 2.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 173 LIRYAPLGILFLIAGKIvemEDMGVigGQLAMY---TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQ-ALITAL 248
Cdd:PRK14695 100 IINLAPFGILGLVFKTI---SDKGV--GSLANYgilLVLLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAF 174
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 249 GTSSSSATLPITFKcLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGA 328
Cdd:PRK14695 175 FTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGA 253
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 329 AGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFL----DRLRTTTNVLGDSLGAGIVEH 384
Cdd:PRK14695 254 SGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDSCETALNSSTDVLFTAVAEY 313
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
56-382 2.27e-10

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 62.15  E-value: 2.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046  56 SAVIVGTILGFALR-PYKMSYREVK----YFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKAS-GKMGMRAVVYYMT 129
Cdd:COG1823   36 TGLGLGILFGLILQlIYGAGSPVIKqsidWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLKNASSlGKISGLIIGILLG 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 130 TTI--------------------IAVVIGIIIVIIIHPGKGTKENMYREGKIVQVTAADAFLDL---------------- 173
Cdd:COG1823  116 TTAiaalvgilvallfgltaeglTQGAAETARGEALEERLGEVEDLSLPQQILSFIPTNPFADLtgarptstiavvifaa 195
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 174 --------------------------------------IRYAPLGILFLIAgKIVEMEDMGVI----GGQLAMYtVTVIV 211
Cdd:COG1823  196 flgiaalglrrkkpeqaetflkgidalqaivmrlvrlvLRLTPYGVLALMT-KVVATSDFADIlnlgKFVVASY-VALII 273
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 212 GLLIHAVIVlpllyfLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTA 291
Cdd:COG1823  274 MFIVHLLLL------ALAGLNPLTYFKKVWPVLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCA 347
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 584277046 292 -LYEALAAIFIAQ---VNNFDLNFgqIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLR 367
Cdd:COG1823  348 gIYPAMLAVMIAPtvgINPLDPSF--ILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGR 425
                        410
                 ....*....|....*
gi 584277046 368 TTTNVlGDSLGAGIV 382
Cdd:COG1823  426 TALNV-SGSMTAGTV 439
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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