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Conserved domains on  [gi|666638004|ref|NP_001287976|]
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peptide chain release factor 1-like, mitochondrial isoform 5 [Homo sapiens]

Protein Classification

PCRF domain-containing protein( domain architecture ID 1750053)

peptide chain release factor (PCRF) domain-containing protein similar to Homo sapiens mitochondrial peptide chain release factor 1 (MTRF1), MTRF1-like and 28S mitochondrial ribosomal protein S35 (MRPS35)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrfA super family cl43066
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 63-232 2.39e-73

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


The actual alignment was detected with superfamily member COG0216:

Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 226.81  E-value: 2.39e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  63 ELLAVIKLLNEKERELRETEHLLHDEN-EDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG-- 139
Cdd:COG0216   44 PIVEAYREYKKLLEDIEEAKELLEEESdPEMREMAKEELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGde 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 140 ----------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:COG0216  124 aalfagdlfrmysryaerkgwkveilsasegelgGYKEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATV 203

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 666638004 186 AILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:COG0216  204 AVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 250
 
Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 63-232 2.39e-73

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 226.81  E-value: 2.39e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  63 ELLAVIKLLNEKERELRETEHLLHDEN-EDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG-- 139
Cdd:COG0216   44 PIVEAYREYKKLLEDIEEAKELLEEESdPEMREMAKEELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGde 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 140 ----------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:COG0216  124 aalfagdlfrmysryaerkgwkveilsasegelgGYKEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATV 203

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 666638004 186 AILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:COG0216  204 AVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 250
prfA PRK00591
peptide chain release factor 1; Validated
 63-232 3.22e-71

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 221.49  E-value: 3.22e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  63 ELLAVIKLLNEKERELRETEHLLHDEN-EDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG-- 139
Cdd:PRK00591  46 PIVEAYREYKQAQEDLEEAKEMLEEESdPEMREMAKEELKELEERLEELEEELKILLLPKDPNDDKNVILEIRAGTGGde 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 140 ----------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:PRK00591 126 aalfagdlfrmysryaerqgwkveilsasegelgGYKEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATV 205

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 666638004 186 AILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:PRK00591 206 AVLPEAEEVEVEINPKDLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 252
prfA TIGR00019
peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, ...
 60-232 7.12e-64

peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. [Protein synthesis, Translation factors]


Pssm-ID: 129130 [Multi-domain]  Cd Length: 360  Bit Score: 202.62  E-value: 7.12e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004   60 RRPELLAVIKLLNEKER---ELRETEHLLHDENEDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAG 136
Cdd:TIGR00019  41 EYSQLEEIVDCYREYQQaqeDIKEAKEILEESDPEMREMAKEELEELEEKIEELEEQLKVLLLPKDPNDEKNVILEIRAG 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  137 VGG------------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHT 180
Cdd:TIGR00019 121 TGGdeaaifagdlfrmysryaeskgwkveilsanetelgGYKEVIAEIKGDGVYSRLKFESGVHRVQRVPVTESQGRIHT 200

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 666638004  181 STMTVAILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:TIGR00019 201 SAATVAVMPELEEVEVDINPADLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 252
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 63-185 2.29e-41

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 139.44  E-value: 2.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004   63 ELLAVIKLLNEKERELRETEHLLHDEneDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG--- 139
Cdd:pfam03462  36 PIVEAYREYKQALEDLEEAKELLEDP--ELAELAEEELEELEKRLEELEEELKLLLLPKDPNDDKNAILEIRAGAGGdea 113

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 666638004  140 ---------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:pfam03462 114 alfagdlfrmytryaerkgwkvevldyseteagGIKEATFEISGEGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
 
Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 63-232 2.39e-73

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 226.81  E-value: 2.39e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  63 ELLAVIKLLNEKERELRETEHLLHDEN-EDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG-- 139
Cdd:COG0216   44 PIVEAYREYKKLLEDIEEAKELLEEESdPEMREMAKEELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGde 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 140 ----------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:COG0216  124 aalfagdlfrmysryaerkgwkveilsasegelgGYKEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATV 203

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 666638004 186 AILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:COG0216  204 AVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 250
prfA PRK00591
peptide chain release factor 1; Validated
 63-232 3.22e-71

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 221.49  E-value: 3.22e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  63 ELLAVIKLLNEKERELRETEHLLHDEN-EDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG-- 139
Cdd:PRK00591  46 PIVEAYREYKQAQEDLEEAKEMLEEESdPEMREMAKEELKELEERLEELEEELKILLLPKDPNDDKNVILEIRAGTGGde 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 140 ----------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:PRK00591 126 aalfagdlfrmysryaerqgwkveilsasegelgGYKEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATV 205

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 666638004 186 AILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:PRK00591 206 AVLPEAEEVEVEINPKDLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 252
prfA TIGR00019
peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, ...
 60-232 7.12e-64

peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. [Protein synthesis, Translation factors]


Pssm-ID: 129130 [Multi-domain]  Cd Length: 360  Bit Score: 202.62  E-value: 7.12e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004   60 RRPELLAVIKLLNEKER---ELRETEHLLHDENEDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAG 136
Cdd:TIGR00019  41 EYSQLEEIVDCYREYQQaqeDIKEAKEILEESDPEMREMAKEELEELEEKIEELEEQLKVLLLPKDPNDEKNVILEIRAG 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  137 VGG------------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHT 180
Cdd:TIGR00019 121 TGGdeaaifagdlfrmysryaeskgwkveilsanetelgGYKEVIAEIKGDGVYSRLKFESGVHRVQRVPVTESQGRIHT 200

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 666638004  181 STMTVAILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:TIGR00019 201 SAATVAVMPELEEVEVDINPADLRIDTFRSSGAGGQHVNTTDSAVRITHLPT 252
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 63-185 2.29e-41

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 139.44  E-value: 2.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004   63 ELLAVIKLLNEKERELRETEHLLHDEneDLRKLAENEITLCQKEITQLKHQIILLLVPSEETDENDLILEVTAGVGG--- 139
Cdd:pfam03462  36 PIVEAYREYKQALEDLEEAKELLEDP--ELAELAEEELEELEKRLEELEEELKLLLLPKDPNDDKNAILEIRAGAGGdea 113

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 666638004  140 ---------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTV 185
Cdd:pfam03462 114 alfagdlfrmytryaerkgwkvevldyseteagGIKEATFEISGEGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 58-232 8.40e-36

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 129.89  E-value: 8.40e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004   58 KVRRPELLAVIKLLNEKERELRETEHLLHDEN-EDLRKLAENEITLCQKEITQLKHQIILllvpSEETDENDLILEVTAG 136
Cdd:TIGR00020  58 RSSLEAVLDTLEELKNSLEDLSELLELAVEEDdEETFNELDAELKALEKKLAELELRTML----SGEYDANNAYLTIQAG 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  137 VGG------------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHT 180
Cdd:TIGR00020 134 AGGteaqdwasmlyrmylrwaerrgfkveiidysegeeaGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHT 213

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 666638004  181 STMTVAILPQPTE-INLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:TIGR00020 214 SFASVFVMPEVDDdIDIEIKPEDLRIDTYRASGAGGQHVNKTDSAVRITHIPT 266
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 71-232 2.16e-31

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 117.21  E-value: 2.16e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  71 LNEKERELRETEHLLHDENEDLRKLAENEITLCQKEITQLKHQIILllvpSEETDENDLILEVTAGVGG----------- 139
Cdd:PRK05589  33 LRNRIEDIEVLCEMMSEEDDEMKKEIISEVKNIKEEIDRFKIETLL----SGEYDRNNAILTLHSGVGGtdaqdwtemll 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 140 -------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTVAILPQPT-E 193
Cdd:PRK05589 109 rmytrwaekkgykveiidllegdeaGIKSVTLKITGEFAYGYLKAEKGIHRLVRISPFNANGKRQTSFASVEVLPELTdD 188

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 666638004 194 INLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:PRK05589 189 QDIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPT 227
PRK07342 PRK07342
peptide chain release factor 2; Provisional
 53-232 2.31e-28

peptide chain release factor 2; Provisional


Pssm-ID: 235997 [Multi-domain]  Cd Length: 339  Bit Score: 109.58  E-value: 2.31e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  53 SEAHLKVR-RPELLAVIKLLNEKERELRETEHLL----HDENEDLRKLAENEITLCQKEITqlKHQIILLLvpSEETDEN 127
Cdd:PRK07342  13 QEAQKLMReRQQLDDSINGINHLEQTLNDNIELIamgeEEGDKSIVEDAEKTIRDLKDEID--RRQIDALL--SGEADAN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 128 DLILEVTAGVGG------------------------------------GLRHASASIGGSEAYRHMKFEGGVHRVQRVPK 171
Cdd:PRK07342  89 DTYLEVHAGAGGtesqdwasmllrmytrwaerqgrkvevlevhdgeeaGIKSATILVKGHNAYGWLKTESGVHRLVRISP 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 666638004 172 TEKQGRVHTSTMTVAILPQPTE-INLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:PRK07342 169 YDSNARRHTSFASIWVYPVIDDnIEVDVNESDVRIDTYRSSGAGGQHVNTTDSAVRITHIPT 230
PRK06746 PRK06746
peptide chain release factor 2; Provisional
 46-233 9.50e-28

peptide chain release factor 2; Provisional


Pssm-ID: 75726 [Multi-domain]  Cd Length: 326  Bit Score: 107.90  E-value: 9.50e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004  46 FLERQAGSEAHLKVRRP--ELLAVIKLLNEKERELRETEHLLHDE-NEDLRKLAENEITLCQKEITQLKHQIILllvpSE 122
Cdd:PRK06746   6 FWDDQQGAQAVINEANAlkDMVGKFRQLDETFENLEITHELLKEEyDEDLHEELESEVKGLIQEMNEYELQLLL----SD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 123 ETDENDLILEVTAGVGG------------------------------------GLRHASASIGGSEAYRHMKFEGGVHRV 166
Cdd:PRK06746  82 PYDKNNAILELHPGAGGtesqdwgsmllrmytrwaekrgfkvetvdylpgdeaGIKSVTLLIKGHNAYGYLKAEKGVHRL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 666638004 167 QRVPKTEKQGRVHTSTMTVAILPQ-PTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPTD 233
Cdd:PRK06746 162 VRISPFDSSGRRHTSFVSCEVVPEfNDEVEIEVRTEDLKIDTYRASGAGGQHVNTTDSAVRITHTPTN 229
PRK08787 PRK08787
peptide chain release factor 2; Provisional
 130-233 2.68e-26

peptide chain release factor 2; Provisional


Pssm-ID: 136970 [Multi-domain]  Cd Length: 313  Bit Score: 103.58  E-value: 2.68e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666638004 130 ILEVTAGVGGGLRHASASIGGSEAYRHMKFEGGVHRVQRVPKTEKQGRVHTSTMTVAILPQPTE-INLVINPKDLRIDTK 208
Cdd:PRK08787 104 LMEVSGGEVAGIKSATVRIEGEYAYGWLKTEIGVHRLVRKSPFDSDNRRHTSFTSVFVSPEVDDnIEIDINPADLRTDVY 183

                         90       100
                 ....*....|....*....|....*
gi 666638004 209 RASGAGGQHVNTTDSAVRIVHLPTD 233
Cdd:PRK08787 184 RSSGAGGQHVNKTESAVRITHIPTN 208
RF-1 pfam00472
RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and ...
 193-232 1.18e-22

RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.


Pssm-ID: 459823 [Multi-domain]  Cd Length: 111  Bit Score: 88.63  E-value: 1.18e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 666638004  193 EINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:pfam00472   2 EIEIEIDPKDLRIDTFRSSGAGGQHVNKTDSAVRLTHIPT 41
PrfB COG1186
Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein ...
 195-229 1.17e-15

Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein chain release factor PrfB is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440799 [Multi-domain]  Cd Length: 140  Bit Score: 71.32  E-value: 1.17e-15
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 666638004 195 NLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVH 229
Cdd:COG1186   20 EIEIPESDLRIDTYRASGAGGQNVNKVSSAVRLTH 54
release_prfH TIGR03072
putative peptide chain release factor H; Members of this protein family are bacterial proteins ...
 198-232 1.04e-11

putative peptide chain release factor H; Members of this protein family are bacterial proteins homologous to peptide chain release factors 1 (RF-1, product of the prfA gene), and 2 (RF-2, product of the prfB gene). The member from Escherichia coli K-12, designated prfH, appears to be a pseudogene. This class I release factor is always found as the downstream gene of a two-gene operon. [Protein synthesis, Translation factors]


Pssm-ID: 213768  Cd Length: 200  Bit Score: 61.71  E-value: 1.04e-11
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 666638004  198 INPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPT 232
Cdd:TIGR03072 103 ATEDEIRFETLRSSGPGGQHVNKTESAVRATHLAS 137
PRK09256 PRK09256
aminoacyl-tRNA hydrolase;
195-235 5.84e-07

aminoacyl-tRNA hydrolase;


Pssm-ID: 181730 [Multi-domain]  Cd Length: 138  Bit Score: 47.45  E-value: 5.84e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 666638004 195 NLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIV------HLPTDWK 235
Cdd:PRK09256   7 RLVIPENELEWRFIRASGPGGQNVNKVSTAVELRfdiaasSLPEFYK 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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