NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|751130507|ref|NP_001291381|]
View 

6-phosphogluconate dehydrogenase, decarboxylating isoform 3 [Homo sapiens]

Protein Classification

NADP(+)-dependent, decarboxylating phosphogluconate dehydrogenase( domain architecture ID 11417508)

NADP(+)-dependent, decarboxylating phosphogluconate dehydrogenase catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate, as part of the oxidative branch of the pentose phosphate pathway

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Gnd COG0362
6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; 6-phosphogluconate ...
 1-456 0e+00

6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; 6-phosphogluconate dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


:

Pssm-ID: 440131 [Multi-domain]  Cd Length: 467  Bit Score: 840.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:COG0362   13 MGRNLALNIADHGFSVAVYNRTAEKTDAFLAEHGKGKNIVGTYSLEEFVASLERPRKILLMVKAGKPVDAVIEQLLPLLE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFvgsgvsggeegARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGtGEPCCDW 160
Cdd:COG0362   93 PGDIIIDGGNSHFTDTIRREKELAEKGIHFigmgvsggeegALHGPSIMPGGSKEAYELVKPILEAIAAKVD-GEPCVTY 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDT-DGKHLLP 239
Cdd:COG0362  172 IGPDGAGHFVKMVHNGIEYADMQLIAEAYDLLRDGLGLSNDEIAEVFAEWNKGELDSYLIEITADILRKKDPeTGKPLVD 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 240 KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKI 319
Cdd:COG0362  252 VILDKAGQKGTGKWTSQSALDLGVPLPLITEAVFARYLSALKEERVAASKLLPGPEAAPFEGDKEAFIEDLRDALYASKI 331

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 320 ISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVST 399
Cdd:COG0362  332 VSYAQGFALLRAASKEYGWNLDLGEIARIWRGGCIIRARFLDDITEAYDKNPDLPNLLLDPYFADALKKAQPAWRRVVAT 411

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 751130507 400 GVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNW 456
Cdd:COG0362  412 AALAGIPVPAFSSALAYYDSYRSARLPANLIQAQRDYFGAHTYERVDKEGFF-HTEW 467
 
Name Accession Description Interval E-value
Gnd COG0362
6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; 6-phosphogluconate ...
 1-456 0e+00

6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; 6-phosphogluconate dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440131 [Multi-domain]  Cd Length: 467  Bit Score: 840.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:COG0362   13 MGRNLALNIADHGFSVAVYNRTAEKTDAFLAEHGKGKNIVGTYSLEEFVASLERPRKILLMVKAGKPVDAVIEQLLPLLE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFvgsgvsggeegARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGtGEPCCDW 160
Cdd:COG0362   93 PGDIIIDGGNSHFTDTIRREKELAEKGIHFigmgvsggeegALHGPSIMPGGSKEAYELVKPILEAIAAKVD-GEPCVTY 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDT-DGKHLLP 239
Cdd:COG0362  172 IGPDGAGHFVKMVHNGIEYADMQLIAEAYDLLRDGLGLSNDEIAEVFAEWNKGELDSYLIEITADILRKKDPeTGKPLVD 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 240 KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKI 319
Cdd:COG0362  252 VILDKAGQKGTGKWTSQSALDLGVPLPLITEAVFARYLSALKEERVAASKLLPGPEAAPFEGDKEAFIEDLRDALYASKI 331

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 320 ISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVST 399
Cdd:COG0362  332 VSYAQGFALLRAASKEYGWNLDLGEIARIWRGGCIIRARFLDDITEAYDKNPDLPNLLLDPYFADALKKAQPAWRRVVAT 411

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 751130507 400 GVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNW 456
Cdd:COG0362  412 AALAGIPVPAFSSALAYYDSYRSARLPANLIQAQRDYFGAHTYERVDKEGFF-HTEW 467
PRK09287 PRK09287
NADP-dependent phosphogluconate dehydrogenase;
1-460 0e+00

NADP-dependent phosphogluconate dehydrogenase;


Pssm-ID: 236453 [Multi-domain]  Cd Length: 459  Bit Score: 827.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:PRK09287   1 MGKNLALNIASHGYTVAVYNRTPEKTDEFLAEEGKGKKIVPAYTLEEFVASLEKPRKILLMVKAGAPVDAVIEQLLPLLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDW 160
Cdd:PRK09287  81 KGDIIIDGGNSNYKDTIRREKELAEKGIHFIGMGVSGGEEGALHGPSIMPGGQKEAYELVAPILEKIAAKVEDGEPCVTY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD-TDGKHLLP 239
Cdd:PRK09287 161 IGPDGAGHYVKMVHNGIEYGDMQLIAEAYDLLKDGLGLSAEEIADVFAEWNKGELNSYLIEITADILRQKDeETGKPLVD 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 240 KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKfQFDGDKKSFLEDIRKALYASKI 319
Cdd:PRK09287 241 VILDKAGQKGTGKWTSQSALDLGVPLTLITEAVFARYLSSLKDQRVAASKVLSGPAA-KFEGDKAEFIEDVRQALYASKI 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 320 ISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVST 399
Cdd:PRK09287 320 VSYAQGFALLRAASEEYGWDLDLGEIARIWRGGCIIRAQFLQKITDAYEANPDLANLLLDPYFKDILEEYQDALRRVVAL 399

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 751130507 400 GVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNWTGHG 460
Cdd:PRK09287 400 AVQAGIPVPAFSSALSYYDSYRTARLPANLIQAQRDYFGAHTYERTDKEGFF-HTEWSEDG 459
gnd TIGR00873
6-phosphogluconate dehydrogenase (decarboxylating); This model does not specify whether the ...
 1-458 0e+00

6-phosphogluconate dehydrogenase (decarboxylating); This model does not specify whether the cofactor is NADP only (EC 1.1.1.44), NAD only, or both. The model does not assign an EC number for that reason. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273314 [Multi-domain]  Cd Length: 467  Bit Score: 785.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507    1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:TIGR00873  10 MGQNLALNMEDHGFTVSVYNRTPSKTDEFLAEEAKGKSIIGAYSIEDFVQSLERPRKIMLMVKAGAPVDAVIDSLLPLLE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGtGEPCCDW 160
Cdd:TIGR00873  90 KGDIIIDGGNSHYPDTERRYKELKAKGILFVGSGVSGGEEGARKGPSIMPGGSPEAWPLVAPIFQSIAAKVD-GEPCCTW 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPK 240
Cdd:TIGR00873 169 VGPGGAGHYVKMVHNGIEYGDMQLICEAYDILKRGLGLSNEEIAEIFTEWNNGELDSYLIEITADILAKKDEDGNPLVDK 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  241 IRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKII 320
Cdd:TIGR00873 249 ILDTAGQKGTGKWTAINALDLGVPLTLITESVFARYLSSLKEERVAASKVLPGPEAPKKGVDKEEFIEDVRQALYASKII 328

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  321 SYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTG 400
Cdd:TIGR00873 329 SYAQGFMLLREASEEYGWDLNLGEIALIWRGGCIIRSVFLDKITKAFAENPDLENLLLAPYFKQALTDAQSGWRKVVALA 408

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 751130507  401 VQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKP-GQFIHTNWTG 458
Cdd:TIGR00873 409 ITYGIPVPAFSAALSFYDGYRTARLPANLLQAQRDYFGAHTYERTDKPrGEFFHTNWTG 467
6PGD pfam00393
6-phosphogluconate dehydrogenase, C-terminal domain; This family represents the C-terminal ...
 167-456 0e+00

6-phosphogluconate dehydrogenase, C-terminal domain; This family represents the C-terminal all-alpha domain of 6-phosphogluconate dehydrogenase. The domain contains two structural repeats of 5 helices each.


Pssm-ID: 459797  Cd Length: 290  Bit Score: 573.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  167 GHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD-TDGKHLLPKIRDSA 245
Cdd:pfam00393   1 GHYVKMVHNGIEYGDMQLIAEAYDLLKRGLGLSNDEIADVFEEWNKGELDSYLIEITADILRKKDpEDGKPLVDKILDKA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  246 GQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQG 325
Cdd:pfam00393  81 GQKGTGKWTVQEALDLGVPAPTIAEAVFARCLSALKDERVAASKVLPGPPPALFEGDKEAFIEDLRQALYASKIISYAQG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  326 FMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGI 405
Cdd:pfam00393 161 FALLRAASKEYGWNLNLGEIARIWRGGCIIRADFLDKIKEAYKKNPDLSNLLLDPYFAKELKEAQPSWRRVVALAVEAGI 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 751130507  406 PMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGqFIHTNW 456
Cdd:pfam00393 241 PVPALSAALSYYDGYRSERLPANLIQAQRDYFGAHTYERIDKEG-FFHTEW 290
 
Name Accession Description Interval E-value
Gnd COG0362
6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; 6-phosphogluconate ...
 1-456 0e+00

6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; 6-phosphogluconate dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440131 [Multi-domain]  Cd Length: 467  Bit Score: 840.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:COG0362   13 MGRNLALNIADHGFSVAVYNRTAEKTDAFLAEHGKGKNIVGTYSLEEFVASLERPRKILLMVKAGKPVDAVIEQLLPLLE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFvgsgvsggeegARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGtGEPCCDW 160
Cdd:COG0362   93 PGDIIIDGGNSHFTDTIRREKELAEKGIHFigmgvsggeegALHGPSIMPGGSKEAYELVKPILEAIAAKVD-GEPCVTY 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDT-DGKHLLP 239
Cdd:COG0362  172 IGPDGAGHFVKMVHNGIEYADMQLIAEAYDLLRDGLGLSNDEIAEVFAEWNKGELDSYLIEITADILRKKDPeTGKPLVD 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 240 KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKI 319
Cdd:COG0362  252 VILDKAGQKGTGKWTSQSALDLGVPLPLITEAVFARYLSALKEERVAASKLLPGPEAAPFEGDKEAFIEDLRDALYASKI 331

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 320 ISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVST 399
Cdd:COG0362  332 VSYAQGFALLRAASKEYGWNLDLGEIARIWRGGCIIRARFLDDITEAYDKNPDLPNLLLDPYFADALKKAQPAWRRVVAT 411

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 751130507 400 GVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNW 456
Cdd:COG0362  412 AALAGIPVPAFSSALAYYDSYRSARLPANLIQAQRDYFGAHTYERVDKEGFF-HTEW 467
PRK09287 PRK09287
NADP-dependent phosphogluconate dehydrogenase;
1-460 0e+00

NADP-dependent phosphogluconate dehydrogenase;


Pssm-ID: 236453 [Multi-domain]  Cd Length: 459  Bit Score: 827.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:PRK09287   1 MGKNLALNIASHGYTVAVYNRTPEKTDEFLAEEGKGKKIVPAYTLEEFVASLEKPRKILLMVKAGAPVDAVIEQLLPLLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDW 160
Cdd:PRK09287  81 KGDIIIDGGNSNYKDTIRREKELAEKGIHFIGMGVSGGEEGALHGPSIMPGGQKEAYELVAPILEKIAAKVEDGEPCVTY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD-TDGKHLLP 239
Cdd:PRK09287 161 IGPDGAGHYVKMVHNGIEYGDMQLIAEAYDLLKDGLGLSAEEIADVFAEWNKGELNSYLIEITADILRQKDeETGKPLVD 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 240 KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKfQFDGDKKSFLEDIRKALYASKI 319
Cdd:PRK09287 241 VILDKAGQKGTGKWTSQSALDLGVPLTLITEAVFARYLSSLKDQRVAASKVLSGPAA-KFEGDKAEFIEDVRQALYASKI 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 320 ISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVST 399
Cdd:PRK09287 320 VSYAQGFALLRAASEEYGWDLDLGEIARIWRGGCIIRAQFLQKITDAYEANPDLANLLLDPYFKDILEEYQDALRRVVAL 399

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 751130507 400 GVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNWTGHG 460
Cdd:PRK09287 400 AVQAGIPVPAFSSALSYYDSYRTARLPANLIQAQRDYFGAHTYERTDKEGFF-HTEWSEDG 459
gnd TIGR00873
6-phosphogluconate dehydrogenase (decarboxylating); This model does not specify whether the ...
 1-458 0e+00

6-phosphogluconate dehydrogenase (decarboxylating); This model does not specify whether the cofactor is NADP only (EC 1.1.1.44), NAD only, or both. The model does not assign an EC number for that reason. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273314 [Multi-domain]  Cd Length: 467  Bit Score: 785.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507    1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:TIGR00873  10 MGQNLALNMEDHGFTVSVYNRTPSKTDEFLAEEAKGKSIIGAYSIEDFVQSLERPRKIMLMVKAGAPVDAVIDSLLPLLE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGtGEPCCDW 160
Cdd:TIGR00873  90 KGDIIIDGGNSHYPDTERRYKELKAKGILFVGSGVSGGEEGARKGPSIMPGGSPEAWPLVAPIFQSIAAKVD-GEPCCTW 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPK 240
Cdd:TIGR00873 169 VGPGGAGHYVKMVHNGIEYGDMQLICEAYDILKRGLGLSNEEIAEIFTEWNNGELDSYLIEITADILAKKDEDGNPLVDK 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  241 IRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKII 320
Cdd:TIGR00873 249 ILDTAGQKGTGKWTAINALDLGVPLTLITESVFARYLSSLKEERVAASKVLPGPEAPKKGVDKEEFIEDVRQALYASKII 328

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  321 SYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTG 400
Cdd:TIGR00873 329 SYAQGFMLLREASEEYGWDLNLGEIALIWRGGCIIRSVFLDKITKAFAENPDLENLLLAPYFKQALTDAQSGWRKVVALA 408

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 751130507  401 VQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKP-GQFIHTNWTG 458
Cdd:TIGR00873 409 ITYGIPVPAFSAALSFYDGYRTARLPANLLQAQRDYFGAHTYERTDKPrGEFFHTNWTG 467
PTZ00142 PTZ00142
6-phosphogluconate dehydrogenase; Provisional
 1-457 0e+00

6-phosphogluconate dehydrogenase; Provisional


Pssm-ID: 240287 [Multi-domain]  Cd Length: 470  Bit Score: 677.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAK-GTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLL 79
Cdd:PTZ00142  12 MGQNLALNIASRGFKISVYNRTYEKTEEFVKKAKEgNTRVKGYHTLEELVNSLKKPRKVILLIKAGEAVDETIDNLLPLL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  80 DTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTgEPCCD 159
Cdd:PTZ00142  92 EKGDIIIDGGNEWYLNTERRIKRCEEKGILYLGMGVSGGEEGARYGPSLMPGGNKEAYDHVKDILEKCSAKVGD-SPCVT 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 160 WVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL-KFQDTDGKHLL 238
Cdd:PTZ00142 171 YVGPGSSGHYVKMVHNGIEYGDMQLISESYKLMKHILGMSNEELSEVFNKWNEGILNSYLIEITAKILaKKDDLGEEHLV 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 239 PKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKF--QFDGDKKSFLEDIRKALYA 316
Cdd:PTZ00142 251 DKILDIAGSKGTGKWTVQEALERGIPVPTMAASVDARNISALKEERTKASSHLAGPNPAnkTETEDKKYFIDDLKNALYC 330

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 317 SKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRA 396
Cdd:PTZ00142 331 SKIISYTQGFFLIKEASKEFGWNLNLGEIARIWRGGCIIRAVFLDRIKNAFKKNPQLDLLFLDPDFNDELKNKQPSWRKV 410

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 751130507 397 VSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNWT 457
Cdd:PTZ00142 411 VSMATKNGIPTPAFSASLAYYQMYRSQNLPANLVQAQRDYFGAHTYKRLDRPGAF-HTNWE 470
6PGD pfam00393
6-phosphogluconate dehydrogenase, C-terminal domain; This family represents the C-terminal ...
 167-456 0e+00

6-phosphogluconate dehydrogenase, C-terminal domain; This family represents the C-terminal all-alpha domain of 6-phosphogluconate dehydrogenase. The domain contains two structural repeats of 5 helices each.


Pssm-ID: 459797  Cd Length: 290  Bit Score: 573.63  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  167 GHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD-TDGKHLLPKIRDSA 245
Cdd:pfam00393   1 GHYVKMVHNGIEYGDMQLIAEAYDLLKRGLGLSNDEIADVFEEWNKGELDSYLIEITADILRKKDpEDGKPLVDKILDKA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  246 GQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQG 325
Cdd:pfam00393  81 GQKGTGKWTVQEALDLGVPAPTIAEAVFARCLSALKDERVAASKVLPGPPPALFEGDKEAFIEDLRQALYASKIISYAQG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  326 FMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGI 405
Cdd:pfam00393 161 FALLRAASKEYGWNLNLGEIARIWRGGCIIRADFLDKIKEAYKKNPDLSNLLLDPYFAKELKEAQPSWRRVVALAVEAGI 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 751130507  406 PMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGqFIHTNW 456
Cdd:pfam00393 241 PVPALSAALSYYDGYRSERLPANLIQAQRDYFGAHTYERIDKEG-FFHTEW 290
PLN02350 PLN02350
phosphogluconate dehydrogenase (decarboxylating)
 1-457 0e+00

phosphogluconate dehydrogenase (decarboxylating)


Pssm-ID: 215200 [Multi-domain]  Cd Length: 493  Bit Score: 567.42  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFL--ANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPL 78
Cdd:PLN02350  17 MGQNLALNIAEKGFPISVYNRTTSKVDETVerAKKEGNLPLYGFKDPEDFVLSIQKPRSVIILVKAGAPVDQTIKALSEY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  79 LDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGePCC 158
Cdd:PLN02350  97 MEPGDCIIDGGNEWYENTERRIKEAAEKGLLYLGMGVSGGEEGARNGPSLMPGGSFEAYKNIEDILEKVAAQVDDG-PCV 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 159 DWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQD-TDGKHL 237
Cdd:PLN02350 176 TYIGPGGAGNFVKMVHNGIEYGDMQLISEAYDVLKSVGGLSNEELAEVFAEWNKGELESFLIEITADIFSVKDdKGDGYL 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 238 LPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDG-----DKKSFLEDIRK 312
Cdd:PLN02350 256 VDKILDKTGMKGTGKWTVQQAAELSVAAPTIAASLDARYLSGLKEERVAAAKVFKEAGLEDILSadsgvDKKQLIDDVRQ 335

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 313 ALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLD-DFFKSAVENcQD 391
Cdd:PLN02350 336 ALYASKICSYAQGMNLIRAKSVEKGWNLNLGELARIWKGGCIIRAVFLDRIKKAYDRNPDLASLLVDpEFAKEMVER-QA 414

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 751130507 392 SWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFiHTNWT 457
Cdd:PLN02350 415 AWRRVVSLAINAGISTPGMSASLAYFDTYRRARLPANLVQAQRDYFGAHTYERVDRPGSF-HTEWT 479
PRK09599 PRK09599
NADP-dependent phosphogluconate dehydrogenase;
1-284 5.67e-71

NADP-dependent phosphogluconate dehydrogenase;


Pssm-ID: 236582 [Multi-domain]  Cd Length: 301  Bit Score: 226.94  E-value: 5.67e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDdflanEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:PRK09599  11 MGGNMARRLLRGGHEVVGYDRNPEAVE-----ALAEEGATGADSLEELVAKLPAPRVVWLMVPAGEITDATIDELAPLLS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGepccdW 160
Cdd:PRK09599  86 PGDIVIDGGNSYYKDDIRRAELLAEKGIHFVDVGTSGGVWGLERGYCLMIGGDKEAVERLEPIFKALAPRAEDG-----Y 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 V--GDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKdvlgmAQD---EMAQAFEDWNK-TELDSFLIEITANILKfQDTDG 234
Cdd:PRK09599 161 LhaGPVGAGHFVKMVHNGIEYGMMQAYAEGFELLE-----ASRfdlDLAAVAEVWRRgSVIRSWLLDLTADALA-EDPKL 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 751130507 235 KHLLPKIRDSagqkGTGKWTAISALEYGVPVTLIGEAVFARcLSSLKDER 284
Cdd:PRK09599 235 DEISGYVEDS----GEGRWTVEEAIDLAVPAPVIAAALFMR-FRSRQEDS 279
YqeC COG1023
6-phosphogluconate dehydrogenase (decarboxylating) [Carbohydrate transport and metabolism];
1-283 2.35e-70

6-phosphogluconate dehydrogenase (decarboxylating) [Carbohydrate transport and metabolism];


Pssm-ID: 440646 [Multi-domain]  Cd Length: 300  Bit Score: 225.36  E-value: 2.35e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFlanEAKGtkVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLD 80
Cdd:COG1023   11 MGGNMARRLLRHGHEVVGYDRNPEAVAAL---AAEG--ATGADSLEELVAKLPAPRVVWLMVPAGEITDQVIEELAPLLE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGepcCDW 160
Cdd:COG1023   86 PGDIVIDGGNSNYKDDIRRAEELAEKGIHFVDVGTSGGVWGLENGYCLMIGGDKEAVERLEPIFKALAPGAENG---YLH 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507 161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDvlgmAQDE--MAQAFEDWNK-TELDSFLIEITANILKfQDTDGKHL 237
Cdd:COG1023  163 CGPVGAGHFVKMVHNGIEYGMMQAYAEGFELLEA----SEFDldLAEVAEVWRRgSVIRSWLLDLTADALA-EDPKLEGI 237

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 751130507 238 LPKIRDSagqkGTGKWTAISALEYGVPVTLIGEAVFARcLSSLKDE 283
Cdd:COG1023  238 SGYVEDS----GEGRWTVEEAIELGVPAPVITAALFAR-FRSRQED 278
gnd_rel TIGR00872
6-phosphogluconate dehydrogenase (decarboxylating); This family resembles a larger family (gnd) ...
 1-282 1.76e-43

6-phosphogluconate dehydrogenase (decarboxylating); This family resembles a larger family (gnd) of bacterial and eukaryotic 6-phosphogluconate dehydrogenases but differs from it by a deep split in a UPGMA similarity clustering tree and the lack of a central region of about 140 residues. Among complete genomes, it is found is found in Bacillus subtilis and Mycobacterium tuberculosis, both of which also contain gnd, and in Aquifex aeolicus. The protein from Methylobacillus flagellatus KT has been characterized as a decarboxylating 6-phosphogluconate dehydrogenase as part of an unusual formaldehyde oxidation cycle. In some sequenced organisms members of this family are the sole 6-phosphogluconate dehydrogenase present and are probably active in the pentose phosphate cycle. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273313 [Multi-domain]  Cd Length: 298  Bit Score: 155.00  E-value: 1.76e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507    1 MGQNLILNMNDHGFVVCAFNRTVSKVDdflanEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGqAVDDFIEKLVPLLD 80
Cdd:TIGR00872  11 MGANIVRRLAKRGHDCVGYDHDQDAVK-----AMKEDRTTGVANLRELSQRLSAPRVVWVMVPHG-IVDAVLEELAPTLE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   81 TGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKvgtgEPCCDW 160
Cdd:TIGR00872  85 KGDIVIDGGNSYYKDSLRRYKLLKEKGIHLLDCGTSGGVWGRERGYCFMIGGDGEAFARAEPLFADVAPE----EQGYLY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  161 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDvlGMAQDEMAQAFEDWNK-TELDSFLIEITANILKfQDTDGKHLLP 239
Cdd:TIGR00872 161 CGPCGSGHFVKMVHNGIEYGMMAAIAEGFEILRN--SQFDFDIPEVARVWRRgSVIRSWLLDLTAIAFR-ESPDLAEFSG 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 751130507  240 KIRDSagqkGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKD 282
Cdd:TIGR00872 238 RVSDS----GEGRWTVIAAIDLGVPAPVIATSLQSRFASRDLD 276
NAD_binding_2 pfam03446
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ...
 1-162 5.30e-42

NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.


Pssm-ID: 427298 [Multi-domain]  Cd Length: 159  Bit Score: 146.46  E-value: 5.30e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507    1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGtkvvgAQSLKEMVSKLkkpRRIILLVKAGQAVDDFI--EKLVPL 78
Cdd:pfam03446  10 MGSPMALNLLKAGYTVTVYNRTPEKVEELVAAGAIA-----AASPAEFVAGL---DVVITMVPAGAAVDAVIfgEGLLPG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   79 LDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGP-SLMPGGNKEAWPHIKTIFQGIAAkvgtgepC 157
Cdd:pfam03446  82 LKPGDIIIDGSTSSPEDARRRAKELKEKGLHFLDAPVSGGEAGAENGTlSIMVGGDEEAFERVKPILEAMGA-------C 154


                  ....*
gi 751130507  158 CDWVG 162
Cdd:pfam03446 155 VTYIG 159
MmsB COG2084
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport ...
 1-210 1.04e-12

3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism];


Pssm-ID: 441687 [Multi-domain]  Cd Length: 285  Bit Score: 68.22  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507   1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFlanEAKGTKVvgAQSLKEMVSKLkkpRRIILLVKAGQAVDDFI---EKLVP 77
Cdd:COG2084   12 MGAPMARNLLKAGHEVTVWNRTPAKAEAL---VAAGARV--AASPAEAAAAA---DVVITMLPDDAAVEEVLlgeDGLLA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751130507  78 LLDTGDIIIDGGNSEYRDTTRRCRDLKAKGIlfvgsgvsggeegaRY-------GP--------SLMPGGNKEAWPHIKT 142
Cdd:COG2084   84 ALRPGAVVVDMSTISPETARELAAAAAARGV--------------RYldapvsgGPagaeagtlTIMVGGDEAAFERARP 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 751130507 143 IFQGIAAKVgtgepccDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDvLGMAQDEMAQAFEDW 210
Cdd:COG2084  150 VLEAMGKRI-------VHVGDAGAGQAAKLANNLLLAGTMAALAEALALAEK-AGLDPETLLEVLSGG 209
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH