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Conserved domains on  [gi|752507721|ref|NP_001291493|]
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mitochondrial dynamics protein MIEF1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Mab-21 super family cl03978
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
191-321 1.55e-04

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam03281:

Pssm-ID: 460873  Cd Length: 191  Bit Score: 42.80  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752507721  191 YDDLQVVTADHIQLIVPLVLEQNLwscipgEDTIMNVPGFFLVRRENPEY-------FPRGSSYWDRCVVGGYLSPKTVA 263
Cdd:pfam03281   2 YENLKVLSPDEFDVMLPLRGPMND------LIIVMGVPGYVVLKLTRWRYylhnpvgRPESLSQWLEFTAEGYLSAAKVL 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 752507721  264 DTFEKVVAGSINwPAIGSLLDYVIRPAPPPEALTLEVQyERDKHLFIDFLPSVTLGDT 321
Cdd:pfam03281  76 SRFQSLVEKALN-TVNDSIYGLVYKREKGGPAVTLAIE-TSEDQYSVDLVPAIECPGI 131
Mab-21_C super family cl48430
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
359-431 3.59e-04

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam20266:

Pssm-ID: 466416  Cd Length: 102  Bit Score: 39.91  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752507721  359 CRSLCLKILKAIC-----KSTPALGHLTASQLTNVILH-LAQ--EEADWSPDMLADRFLQALRGLISYLEAGVLPSALNP 430
Cdd:pfam20266   1 CRKKCLRILKKLKepgkrDVKTELSKICSYHLKTLFLWeCEKhpDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHFFIP 80

                  .
gi 752507721  431 K 431
Cdd:pfam20266  81 K 81
 
Name Accession Description Interval E-value
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
191-321 1.55e-04

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 460873  Cd Length: 191  Bit Score: 42.80  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752507721  191 YDDLQVVTADHIQLIVPLVLEQNLwscipgEDTIMNVPGFFLVRRENPEY-------FPRGSSYWDRCVVGGYLSPKTVA 263
Cdd:pfam03281   2 YENLKVLSPDEFDVMLPLRGPMND------LIIVMGVPGYVVLKLTRWRYylhnpvgRPESLSQWLEFTAEGYLSAAKVL 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 752507721  264 DTFEKVVAGSINwPAIGSLLDYVIRPAPPPEALTLEVQyERDKHLFIDFLPSVTLGDT 321
Cdd:pfam03281  76 SRFQSLVEKALN-TVNDSIYGLVYKREKGGPAVTLAIE-TSEDQYSVDLVPAIECPGI 131
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
359-431 3.59e-04

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 39.91  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752507721  359 CRSLCLKILKAIC-----KSTPALGHLTASQLTNVILH-LAQ--EEADWSPDMLADRFLQALRGLISYLEAGVLPSALNP 430
Cdd:pfam20266   1 CRKKCLRILKKLKepgkrDVKTELSKICSYHLKTLFLWeCEKhpDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHFFIP 80

                  .
gi 752507721  431 K 431
Cdd:pfam20266  81 K 81
 
Name Accession Description Interval E-value
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
191-321 1.55e-04

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 460873  Cd Length: 191  Bit Score: 42.80  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752507721  191 YDDLQVVTADHIQLIVPLVLEQNLwscipgEDTIMNVPGFFLVRRENPEY-------FPRGSSYWDRCVVGGYLSPKTVA 263
Cdd:pfam03281   2 YENLKVLSPDEFDVMLPLRGPMND------LIIVMGVPGYVVLKLTRWRYylhnpvgRPESLSQWLEFTAEGYLSAAKVL 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 752507721  264 DTFEKVVAGSINwPAIGSLLDYVIRPAPPPEALTLEVQyERDKHLFIDFLPSVTLGDT 321
Cdd:pfam03281  76 SRFQSLVEKALN-TVNDSIYGLVYKREKGGPAVTLAIE-TSEDQYSVDLVPAIECPGI 131
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
359-431 3.59e-04

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 39.91  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752507721  359 CRSLCLKILKAIC-----KSTPALGHLTASQLTNVILH-LAQ--EEADWSPDMLADRFLQALRGLISYLEAGVLPSALNP 430
Cdd:pfam20266   1 CRKKCLRILKKLKepgkrDVKTELSKICSYHLKTLFLWeCEKhpDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHFFIP 80

                  .
gi 752507721  431 K 431
Cdd:pfam20266  81 K 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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