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Conserved domains on  [gi|815930028|ref|NP_001295246|]
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coiled-coil domain-containing protein 14 isoform 2 [Homo sapiens]

Protein Classification

CCDC14 domain-containing protein( domain architecture ID 12172588)

CCDC14 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CCDC14 pfam15254
Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing ...
1-753 0e+00

Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing protein 14 (CCDC14) is a domain of unknown function. This family of proteins is found in eukaryotes. Proteins in this family are typically between 301 and 912 amino acids in length.


:

Pssm-ID: 464594  Cd Length: 857  Bit Score: 1341.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028    1 MYSPIIYQALCEHVQTQMSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQT 80
Cdd:pfam15254 105 MYSPIIYQALCEHVQTQMSLMNNLASKNSPNGIPAVPCHTVSGSESQATTASNYGLPTSTPVLSPQHPACPLVVHSEVQT 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   81 DGNSQFASQGKTVSATCT-DVLRNSFNTSPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFR 159
Cdd:pfam15254 185 DSDNQFASQGGTTSVNCTmDVPRNSFSASPGVPCSLPQTDAPAIPTFQQLSLANGILPQQQQLKEADLLKCIQTHLSLLQ 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  160 SHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLG 239
Cdd:pfam15254 265 SHEKDNHPDSQTCQSPTQLQPAFLATNEEKCAREQIEETTSEGKDLNLHVVDIKPVKDVQKAKNVNQTAEKVRTVKYLLG 344
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  240 ELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKPSGAVD 319
Cdd:pfam15254 345 ELKALVADQEDSEVLRLITEVEACVSLLPAVSGNTNIQAEIALALQPLRSENAQLRRQLRILNQQLREQEKTEKTSGSGD 424
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  320 CNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQYDIEITRIKIELE 399
Cdd:pfam15254 425 CNLELFSLQSLNMSLQNQLQESLKSQELLQSKNEELLKVIENQKEENKKLTKIFKEKEQTLLENKQQFDIETTRVKIELE 504
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  400 EALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNLTKSLLNIHDKQL 479
Cdd:pfam15254 505 EALVNMKSFQFKLEAAEKENQILGITLRQRDAEVTRLRELTRTLQGSMAKLLSDLSMDTARPKPGNNLTKSLLNIYDKQL 584
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  480 QHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQDSD 559
Cdd:pfam15254 585 QHDPAPAHTSIMSYLKKLETNHSFTHSEPLSTIKNEETIEPNRPYENVLPSKGPQHSNTRAMEEVSAPGIISALSKQDSD 664
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  560 EGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICsSSTKEAE 639
Cdd:pfam15254 665 TESETTTLIEDEHNLDETIYIPFARSTSKKKSPLSKRLSPQPQISVATKQLDSGSGLSVSEQENKLCAPKVC-SSKKEAE 743
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  640 DAPEKLSRASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFST 719
Cdd:pfam15254 744 DAPEKLSRTADTEDKQLLKKIKEAIGKIPAAAEDPEEQAACHGPSACQSGHVQVKGSSVSDSSFLNSDLMSDWSISSFST 823
                         730       740       750
                  ....*....|....*....|....*....|....
gi 815930028  720 FTSRDEQDFRNGLAALDANIARLQKSLRTGLLEK 753
Cdd:pfam15254 824 FTSRDEQDFRNGLAALDANIARLQKSLRSGLLEK 857
 
Name Accession Description Interval E-value
CCDC14 pfam15254
Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing ...
1-753 0e+00

Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing protein 14 (CCDC14) is a domain of unknown function. This family of proteins is found in eukaryotes. Proteins in this family are typically between 301 and 912 amino acids in length.


Pssm-ID: 464594  Cd Length: 857  Bit Score: 1341.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028    1 MYSPIIYQALCEHVQTQMSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQT 80
Cdd:pfam15254 105 MYSPIIYQALCEHVQTQMSLMNNLASKNSPNGIPAVPCHTVSGSESQATTASNYGLPTSTPVLSPQHPACPLVVHSEVQT 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   81 DGNSQFASQGKTVSATCT-DVLRNSFNTSPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFR 159
Cdd:pfam15254 185 DSDNQFASQGGTTSVNCTmDVPRNSFSASPGVPCSLPQTDAPAIPTFQQLSLANGILPQQQQLKEADLLKCIQTHLSLLQ 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  160 SHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLG 239
Cdd:pfam15254 265 SHEKDNHPDSQTCQSPTQLQPAFLATNEEKCAREQIEETTSEGKDLNLHVVDIKPVKDVQKAKNVNQTAEKVRTVKYLLG 344
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  240 ELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKPSGAVD 319
Cdd:pfam15254 345 ELKALVADQEDSEVLRLITEVEACVSLLPAVSGNTNIQAEIALALQPLRSENAQLRRQLRILNQQLREQEKTEKTSGSGD 424
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  320 CNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQYDIEITRIKIELE 399
Cdd:pfam15254 425 CNLELFSLQSLNMSLQNQLQESLKSQELLQSKNEELLKVIENQKEENKKLTKIFKEKEQTLLENKQQFDIETTRVKIELE 504
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  400 EALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNLTKSLLNIHDKQL 479
Cdd:pfam15254 505 EALVNMKSFQFKLEAAEKENQILGITLRQRDAEVTRLRELTRTLQGSMAKLLSDLSMDTARPKPGNNLTKSLLNIYDKQL 584
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  480 QHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQDSD 559
Cdd:pfam15254 585 QHDPAPAHTSIMSYLKKLETNHSFTHSEPLSTIKNEETIEPNRPYENVLPSKGPQHSNTRAMEEVSAPGIISALSKQDSD 664
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  560 EGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICsSSTKEAE 639
Cdd:pfam15254 665 TESETTTLIEDEHNLDETIYIPFARSTSKKKSPLSKRLSPQPQISVATKQLDSGSGLSVSEQENKLCAPKVC-SSKKEAE 743
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  640 DAPEKLSRASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFST 719
Cdd:pfam15254 744 DAPEKLSRTADTEDKQLLKKIKEAIGKIPAAAEDPEEQAACHGPSACQSGHVQVKGSSVSDSSFLNSDLMSDWSISSFST 823
                         730       740       750
                  ....*....|....*....|....*....|....
gi 815930028  720 FTSRDEQDFRNGLAALDANIARLQKSLRTGLLEK 753
Cdd:pfam15254 824 FTSRDEQDFRNGLAALDANIARLQKSLRSGLLEK 857
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
181-465 2.09e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.00  E-value: 2.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 181 AFLATNEEKCAREQIREATSERKDLNIHVRdtktvkdvQKAKNVNKTAEKvriIKYLLGELKALvaEQEDSEIQRLITEM 260
Cdd:COG4942    8 ALLLALAAAAQADAAAEAEAELEQLQQEIA--------ELEKELAALKKE---EKALLKQLAAL--ERRIAALARRIRAL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 261 EACISvlptvsgntDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKtqkpSGAVDCNLELFSLQSLNmslqnqleE 340
Cdd:COG4942   75 EQELA---------ALEAELAELEKEIAELRAELEAQKEELAELLRALYR----LGRQPPLALLLSPEDFL--------D 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 341 SLKSQELLQSKNEELLKVIENQKdenkkfssifkdKDQTILENKQQydiEITRIKIELEEALVNVKSSQFKLETAEKENQ 420
Cdd:COG4942  134 AVRRLQYLKYLAPARREQAEELR------------ADLAELAALRA---ELEAERAELEALLAELEEERAALEALKAERQ 198
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 815930028 421 ILGITLRQR----DAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGN 465
Cdd:COG4942  199 KLLARLEKElaelAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
183-450 6.91e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 6.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   183 LATNEEKCAR--EQIREATSERKDLNIHVRD-TKTVKDVQKAKNvnktaEKVRIIKYLLGELKALVAEQEDSEIQRLITE 259
Cdd:TIGR02168  679 IEELEEKIEEleEKIAELEKALAELRKELEElEEELEQLRKELE-----ELSRQISALRKDLARLEAEVEQLEERIAQLS 753
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   260 MEacisvlptvsgNTDIQVEIALAMQPLRSENAQLRRQLRILnQQLREQQKTQKpsgavdcnLELFSLQSLNMSLQNQLE 339
Cdd:TIGR02168  754 KE-----------LTELEAEIEELEERLEEAEEELAEAEAEI-EELEAQIEQLK--------EELKALREALDELRAELT 813
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   340 ESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQ---YDIEITRIKIELEEALVNVKSSQFKLETAE 416
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLR 893
                          250       260       270
                   ....*....|....*....|....*....|....
gi 815930028   417 KENQILGITLRQRDAEVTRLRELTRTLQTSMAKL 450
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELREKLAQL 927
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
218-481 8.07e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.67  E-value: 8.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  218 VQKAKNVNKTAEKVRIIKYLLGELKalvaeQEDSEIQRLITEMEACISVLPTVSG------NTDIQVEIA--------LA 283
Cdd:PRK10929  119 LEKSRQAQQEQDRAREISDSLSQLP-----QQQTEARRQLNEIERRLQTLGTPNTplaqaqLTALQAESAalkalvdeLE 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  284 MQPLRSENAQLRRQLRILNQQLREQQKtqkpsgavdcNLELFSLQS-LNMSLQNQLEESLKSQELLQSKNEELLKVIENQ 362
Cdd:PRK10929  194 LAQLSANNRQELARLRSELAKKRSQQL----------DAYLQALRNqLNSQRQREAERALESTELLAEQSGDLPKSIVAQ 263
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  363 KDENKKFSSIFKDKDQTI-LENKQQYdiEITRIKIELEEALVNVKssqfklETAE--KENQILGITLRqrdAEVTRLREL 439
Cdd:PRK10929  264 FKINRELSQALNQQAQRMdLIASQQR--QAASQTLQVRQALNTLR------EQSQwlGVSNALGEALR---AQVARLPEM 332
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 815930028  440 TRT--LQTSMAKLL------SDL-----SVDSARCKPGNNLTKSLLNIHDKQLQH 481
Cdd:PRK10929  333 PKPqqLDTEMAQLRvqrlryEDLlnkqpQLRQIRQADGQPLTAEQNRILDAQLRT 387
 
Name Accession Description Interval E-value
CCDC14 pfam15254
Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing ...
1-753 0e+00

Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing protein 14 (CCDC14) is a domain of unknown function. This family of proteins is found in eukaryotes. Proteins in this family are typically between 301 and 912 amino acids in length.


Pssm-ID: 464594  Cd Length: 857  Bit Score: 1341.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028    1 MYSPIIYQALCEHVQTQMSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQT 80
Cdd:pfam15254 105 MYSPIIYQALCEHVQTQMSLMNNLASKNSPNGIPAVPCHTVSGSESQATTASNYGLPTSTPVLSPQHPACPLVVHSEVQT 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   81 DGNSQFASQGKTVSATCT-DVLRNSFNTSPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFR 159
Cdd:pfam15254 185 DSDNQFASQGGTTSVNCTmDVPRNSFSASPGVPCSLPQTDAPAIPTFQQLSLANGILPQQQQLKEADLLKCIQTHLSLLQ 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  160 SHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLG 239
Cdd:pfam15254 265 SHEKDNHPDSQTCQSPTQLQPAFLATNEEKCAREQIEETTSEGKDLNLHVVDIKPVKDVQKAKNVNQTAEKVRTVKYLLG 344
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  240 ELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKPSGAVD 319
Cdd:pfam15254 345 ELKALVADQEDSEVLRLITEVEACVSLLPAVSGNTNIQAEIALALQPLRSENAQLRRQLRILNQQLREQEKTEKTSGSGD 424
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  320 CNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQYDIEITRIKIELE 399
Cdd:pfam15254 425 CNLELFSLQSLNMSLQNQLQESLKSQELLQSKNEELLKVIENQKEENKKLTKIFKEKEQTLLENKQQFDIETTRVKIELE 504
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  400 EALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNLTKSLLNIHDKQL 479
Cdd:pfam15254 505 EALVNMKSFQFKLEAAEKENQILGITLRQRDAEVTRLRELTRTLQGSMAKLLSDLSMDTARPKPGNNLTKSLLNIYDKQL 584
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  480 QHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQDSD 559
Cdd:pfam15254 585 QHDPAPAHTSIMSYLKKLETNHSFTHSEPLSTIKNEETIEPNRPYENVLPSKGPQHSNTRAMEEVSAPGIISALSKQDSD 664
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  560 EGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICsSSTKEAE 639
Cdd:pfam15254 665 TESETTTLIEDEHNLDETIYIPFARSTSKKKSPLSKRLSPQPQISVATKQLDSGSGLSVSEQENKLCAPKVC-SSKKEAE 743
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  640 DAPEKLSRASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFST 719
Cdd:pfam15254 744 DAPEKLSRTADTEDKQLLKKIKEAIGKIPAAAEDPEEQAACHGPSACQSGHVQVKGSSVSDSSFLNSDLMSDWSISSFST 823
                         730       740       750
                  ....*....|....*....|....*....|....
gi 815930028  720 FTSRDEQDFRNGLAALDANIARLQKSLRTGLLEK 753
Cdd:pfam15254 824 FTSRDEQDFRNGLAALDANIARLQKSLRSGLLEK 857
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
181-465 2.09e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.00  E-value: 2.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 181 AFLATNEEKCAREQIREATSERKDLNIHVRdtktvkdvQKAKNVNKTAEKvriIKYLLGELKALvaEQEDSEIQRLITEM 260
Cdd:COG4942    8 ALLLALAAAAQADAAAEAEAELEQLQQEIA--------ELEKELAALKKE---EKALLKQLAAL--ERRIAALARRIRAL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 261 EACISvlptvsgntDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKtqkpSGAVDCNLELFSLQSLNmslqnqleE 340
Cdd:COG4942   75 EQELA---------ALEAELAELEKEIAELRAELEAQKEELAELLRALYR----LGRQPPLALLLSPEDFL--------D 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 341 SLKSQELLQSKNEELLKVIENQKdenkkfssifkdKDQTILENKQQydiEITRIKIELEEALVNVKSSQFKLETAEKENQ 420
Cdd:COG4942  134 AVRRLQYLKYLAPARREQAEELR------------ADLAELAALRA---ELEAERAELEALLAELEEERAALEALKAERQ 198
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 815930028 421 ILGITLRQR----DAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGN 465
Cdd:COG4942  199 KLLARLEKElaelAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
183-450 6.91e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 6.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   183 LATNEEKCAR--EQIREATSERKDLNIHVRD-TKTVKDVQKAKNvnktaEKVRIIKYLLGELKALVAEQEDSEIQRLITE 259
Cdd:TIGR02168  679 IEELEEKIEEleEKIAELEKALAELRKELEElEEELEQLRKELE-----ELSRQISALRKDLARLEAEVEQLEERIAQLS 753
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   260 MEacisvlptvsgNTDIQVEIALAMQPLRSENAQLRRQLRILnQQLREQQKTQKpsgavdcnLELFSLQSLNMSLQNQLE 339
Cdd:TIGR02168  754 KE-----------LTELEAEIEELEERLEEAEEELAEAEAEI-EELEAQIEQLK--------EELKALREALDELRAELT 813
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   340 ESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQ---YDIEITRIKIELEEALVNVKSSQFKLETAE 416
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLR 893
                          250       260       270
                   ....*....|....*....|....*....|....
gi 815930028   417 KENQILGITLRQRDAEVTRLRELTRTLQTSMAKL 450
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELREKLAQL 927
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
218-481 8.07e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.67  E-value: 8.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  218 VQKAKNVNKTAEKVRIIKYLLGELKalvaeQEDSEIQRLITEMEACISVLPTVSG------NTDIQVEIA--------LA 283
Cdd:PRK10929  119 LEKSRQAQQEQDRAREISDSLSQLP-----QQQTEARRQLNEIERRLQTLGTPNTplaqaqLTALQAESAalkalvdeLE 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  284 MQPLRSENAQLRRQLRILNQQLREQQKtqkpsgavdcNLELFSLQS-LNMSLQNQLEESLKSQELLQSKNEELLKVIENQ 362
Cdd:PRK10929  194 LAQLSANNRQELARLRSELAKKRSQQL----------DAYLQALRNqLNSQRQREAERALESTELLAEQSGDLPKSIVAQ 263
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  363 KDENKKFSSIFKDKDQTI-LENKQQYdiEITRIKIELEEALVNVKssqfklETAE--KENQILGITLRqrdAEVTRLREL 439
Cdd:PRK10929  264 FKINRELSQALNQQAQRMdLIASQQR--QAASQTLQVRQALNTLR------EQSQwlGVSNALGEALR---AQVARLPEM 332
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 815930028  440 TRT--LQTSMAKLL------SDL-----SVDSARCKPGNNLTKSLLNIHDKQLQH 481
Cdd:PRK10929  333 PKPqqLDTEMAQLRvqrlryEDLlnkqpQLRQIRQADGQPLTAEQNRILDAQLRT 387
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
194-454 7.14e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 7.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 194 QIREATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIikyllgELKALVAEQEDSEIQRLITEMEACISvlptvsgn 273
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEEL------RLELEELELELEEAQAEEYELLAELA-------- 298
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 274 tdiqvEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKpsgavdcnlelfslqslnmSLQNQLEESLKSQELLQSKNE 353
Cdd:COG1196  299 -----RLEQDIARLEERRRELEERLEELEEELAELEEELE-------------------ELEEELEELEEELEEAEEELE 354
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028 354 ELLKVIENQKDENKKFSSIFKDKDQTILENKQQYdIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEV 433
Cdd:COG1196  355 EAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
                        250       260
                 ....*....|....*....|.
gi 815930028 434 TRLRELTRTLQTSMAKLLSDL 454
Cdd:COG1196  434 EEEEEEEEEALEEAAEEEAEL 454
HAUS-augmin3 pfam14932
HAUS augmin-like complex subunit 3; This domain is subunit three of the augmin complex found ...
270-381 2.30e-03

HAUS augmin-like complex subunit 3; This domain is subunit three of the augmin complex found from Drosophila to humans. The HAUS-augmin complex is made up of eight subunits. The augmin complex interacts with gamma-TuRC, and attenuation of this interaction severely impairs spindle MT generation. Furthermore, we provide evidence that human augmin plays critical and non-redundant roles in the kinetochore-MT attachment and also central spindle formation during anaphase in human cells.The HAUS complex is required for mitotic spindle assembly and for maintenance of centrosome integrity.


Pssm-ID: 464384 [Multi-domain]  Cd Length: 261  Bit Score: 40.38  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  270 VSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQktqkpSGAVDCNLELFSLQSLNMSLQNQLEEslkSQELLQ 349
Cdd:pfam14932  69 VEALEESLEEIREATEDLEAELQELQKTKQLKINRLNKLQ-----AQASSLSQGLRALVAEEEEAAKQLEE---LQEELA 140
                          90       100       110
                  ....*....|....*....|....*....|..
gi 815930028  350 SKNEELLKVIENQKDENKKFSSIFKDKDQTIL 381
Cdd:pfam14932 141 ALNAKTNNVLQSLQSEVKELASFFSASEPPVF 172
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
226-460 3.00e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 3.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   226 KTAEKVRIIK---------YLLGELKALVAEQEdsEIQRLITEMEacisvlptvsgntDIQVEIALAMQPLRSENAQLRR 296
Cdd:TIGR02168  210 EKAERYKELKaelrelelaLLVLRLEELREELE--ELQEELKEAE-------------EELEELTAELQELEEKLEELRL 274
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   297 QLRILNQQLREQQKtqkpsgavdcnlELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIEnqKDENKkfssifKDK 376
Cdd:TIGR02168  275 EVSELEEEIEELQK------------ELYALANEISRLEQQKQILRERLANLERQLEELEAQLE--ELESK------LDE 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028   377 DQTILenkqqydieiTRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSV 456
Cdd:TIGR02168  335 LAEEL----------AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                   ....
gi 815930028   457 DSAR 460
Cdd:TIGR02168  405 LEAR 408
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
334-445 4.73e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 40.26  E-value: 4.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 815930028  334 LQNQLEESLKSQELLQSKNEELLKVIENQKDENKKfssifkdkdqtileNKQQYDIEITRIK---IELEEALVNVKSSQF 410
Cdd:pfam07888  32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKR--------------DREQWERQRRELEsrvAELKEELRQSREKHE 97
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 815930028  411 KLETAEKENQILG--------ITLRQRDAEVTRLRELTRTLQT 445
Cdd:pfam07888  98 ELEEKYKELSASSeelseekdALLAQRAAHEARIRELEEDIKT 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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