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Conserved domains on  [gi|1676324748|ref|NP_001295269|]
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putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DIE2_ALG10 super family cl04845
DIE2/ALG10 family; The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 ...
 32-123 2.25e-32

DIE2/ALG10 family; The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum. This protein has been characterized in rat as potassium channel regulator 1.


The actual alignment was detected with superfamily member pfam04922:

Pssm-ID: 461481  Cd Length: 383  Bit Score: 116.89  E-value: 2.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676324748  32 REPYMDEIFHLPQAQRYCEGHFslSQWDPMITTLPGLYLVSVGVVKPAIWifAWSEHVVCSIGMLRFVNLLFSVgnfYLL 111
Cdd:pfam04922   2 PEPYMDEIFHVPQAQAYCRGNF--TEWDPKITTPPGLYLLSYLLLKPLKL--GCSGSVLCSLAILRLTNLLGGL---LLL 74

                          90
                  ....*....|..
gi 1676324748 112 YLLFHKVQPRNK 123
Cdd:pfam04922  75 PLILRRLLKRLK 86
 
Name Accession Description Interval E-value
DIE2_ALG10 pfam04922
DIE2/ALG10 family; The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 ...
 32-123 2.25e-32

DIE2/ALG10 family; The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum. This protein has been characterized in rat as potassium channel regulator 1.


Pssm-ID: 461481  Cd Length: 383  Bit Score: 116.89  E-value: 2.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676324748  32 REPYMDEIFHLPQAQRYCEGHFslSQWDPMITTLPGLYLVSVGVVKPAIWifAWSEHVVCSIGMLRFVNLLFSVgnfYLL 111
Cdd:pfam04922   2 PEPYMDEIFHVPQAQAYCRGNF--TEWDPKITTPPGLYLLSYLLLKPLKL--GCSGSVLCSLAILRLTNLLGGL---LLL 74

                          90
                  ....*....|..
gi 1676324748 112 YLLFHKVQPRNK 123
Cdd:pfam04922  75 PLILRRLLKRLK 86
 
Name Accession Description Interval E-value
DIE2_ALG10 pfam04922
DIE2/ALG10 family; The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 ...
 32-123 2.25e-32

DIE2/ALG10 family; The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum. This protein has been characterized in rat as potassium channel regulator 1.


Pssm-ID: 461481  Cd Length: 383  Bit Score: 116.89  E-value: 2.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1676324748  32 REPYMDEIFHLPQAQRYCEGHFslSQWDPMITTLPGLYLVSVGVVKPAIWifAWSEHVVCSIGMLRFVNLLFSVgnfYLL 111
Cdd:pfam04922   2 PEPYMDEIFHVPQAQAYCRGNF--TEWDPKITTPPGLYLLSYLLLKPLKL--GCSGSVLCSLAILRLTNLLGGL---LLL 74

                          90
                  ....*....|..
gi 1676324748 112 YLLFHKVQPRNK 123
Cdd:pfam04922  75 PLILRRLLKRLK 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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