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Conserved domains on  [gi|952977824|ref|NP_001304032|]
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dnaJ homolog subfamily B member 4 isoform d [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ_bact super family cl37091
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-71 1.26e-41

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


The actual alignment was detected with superfamily member TIGR02349:

Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 138.12  E-value: 1.26e-41
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824    4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAG 68
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-71 1.26e-41

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 138.12  E-value: 1.26e-41
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824    4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAG 68
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1-71 8.40e-39

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 131.42  E-value: 8.40e-39
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPgDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAA 73
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 4-65 4.31e-33

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 108.33  E-value: 4.31e-33
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952977824   4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKN-KSPQAEEKFKEVAEAYEVLSDPKKREIYD 65
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 4-70 1.31e-32

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 109.41  E-value: 1.31e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824   4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKS-PQAEEKFKEVAEAYEVLSDPKKREIYDQFGEE 70
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGdPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHA 68
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-72 4.49e-30

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 109.52  E-value: 4.49e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:NF037946   5 RDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKAPDAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV 74
DnaJ smart00271
DnaJ molecular chaperone homology domain;
3-60 8.54e-25

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 87.29  E-value: 8.54e-25
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824    3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKS--PQAEEKFKEVAEAYEVLSDPKK 60
Cdd:smart00271  1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGdkEEAEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 4-57 2.11e-24

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 86.06  E-value: 2.11e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 952977824  4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKS-PQAEEKFKEVAEAYEVLSD 57
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDdPEAEEKFKEINEAYEVLSD 55
 
Name Accession Description Interval E-value
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-71 1.26e-41

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 138.12  E-value: 1.26e-41
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824    4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAG 68
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 1-71 8.40e-39

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 131.42  E-value: 8.40e-39
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK10767   2 AKRDYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPgDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYGHAA 73
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 3-72 4.01e-36

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 124.58  E-value: 4.01e-36
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14298   5 RDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKEPDAEEKFKEISEAYAVLSDAEKRAQYDRFGHAGI 74
PRK14293 PRK14293
molecular chaperone DnaJ;
1-72 1.32e-34

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 120.48  E-value: 1.32e-34
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14293   1 MAADYYEILGVSRDADKDELKRAYRRLARKYHPDVNKEPGAEDRFKEINRAYEVLSDPETRARYDQFGEAGV 72
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 3-71 3.35e-33

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 116.73  E-value: 3.35e-33
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK14276   4 TEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKEPGAEEKYKEVQEAYETLSDPQKRAAYDQYGAAG 72
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 4-65 4.31e-33

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 108.33  E-value: 4.31e-33
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952977824   4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKN-KSPQAEEKFKEVAEAYEVLSDPKKREIYD 65
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 1-73 1.03e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 115.64  E-value: 1.03e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGIV 73
Cdd:PRK14291   1 AKKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNKNPEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFS 73
PRK14297 PRK14297
molecular chaperone DnaJ;
3-68 1.06e-32

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 115.65  E-value: 1.06e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFG 68
Cdd:PRK14297   4 KDYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKgNKEAEEKFKEINEAYQVLSDPQKKAQYDQFG 70
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 4-70 1.31e-32

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 109.41  E-value: 1.31e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824   4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKS-PQAEEKFKEVAEAYEVLSDPKKREIYDQFGEE 70
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGdPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHA 68
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 3-72 1.42e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 114.86  E-value: 1.42e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14294   4 RDYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPgDKEAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGL 74
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 1-69 3.49e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 113.99  E-value: 3.49e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGE 69
Cdd:PRK14278   1 MARDYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPDEEAQEKFKEISVAYEVLSDPEKRRIVDLGGD 69
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 1-72 8.43e-32

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 112.91  E-value: 8.43e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKN-KSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14301   2 SQRDYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNpDNPEAEQKFKEAAEAYEVLRDAEKRARYDRFGHAGV 74
PRK14289 PRK14289
molecular chaperone DnaJ;
3-72 1.23e-31

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 112.62  E-value: 1.23e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14289   5 RDYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPgDKEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGV 75
PRK14280 PRK14280
molecular chaperone DnaJ;
1-71 1.80e-31

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 112.12  E-value: 1.80e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 952977824   1 MGK-DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK14280   1 MAKrDYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDQKRAQYDQFGHAG 72
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 3-70 7.20e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 108.87  E-value: 7.20e-31
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEE 70
Cdd:PRK14299   4 KDYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKSPGAEEKFKEINEAYTVLSDPEKRRIYDTYGTT 71
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 3-72 1.44e-30

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 109.69  E-value: 1.44e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14286   4 RSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKgNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGV 74
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-72 4.49e-30

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 109.52  E-value: 4.49e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:NF037946   5 RDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKAPDAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV 74
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 1-71 1.43e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 107.19  E-value: 1.43e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK14277   3 AKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPgDKEAEQKFKEINEAYEILSDPQKRAQYDQFGHAA 74
PRK14295 PRK14295
molecular chaperone DnaJ;
3-71 2.24e-29

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 106.86  E-value: 2.24e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQ----FGEEG 71
Cdd:PRK14295   9 KDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKgDAKAEERFKEISEAYDVLSDEKKRKEYDEarslFGNGG 82
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 4-71 3.94e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 106.08  E-value: 3.94e-29
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 952977824   4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPgDAEAEKRFKEVSEAYEVLSDAQKRESYDRYGKDG 70
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 3-72 5.18e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 105.68  E-value: 5.18e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14283   5 RDYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEEEGAEEKFKEISEAYAVLSDDEKRQRYDQFGHAGM 74
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 1-72 1.10e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 105.28  E-value: 1.10e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKN-KSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14281   1 MKRDYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNpDNKEAEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGV 73
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 1-68 3.20e-28

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 103.47  E-value: 3.20e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKN--KSPQAEEKFKEVAEAYEVLSDPKKREIYDQFG 68
Cdd:PRK14290   1 MAKDYYKILGVDRNASQEDIKKAFRELAKKWHPDLHpgNKAEAEEKFKEISEAYEVLSDPQKRRQYDQTG 70
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 4-68 4.05e-26

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 98.04  E-value: 4.05e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 952977824   4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFG 68
Cdd:PRK14292   3 DYYELLGVSRTASADEIKSAYRKLALKYHPDRNKEKGAAEKFAQINEAYAVLSDAEKRAHYDRFG 67
PRK14279 PRK14279
molecular chaperone DnaJ;
3-67 6.26e-26

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 97.50  E-value: 6.26e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQF 67
Cdd:PRK14279   9 KDFYKELGVSSDASAEEIKKAYRKLARELHPDANPgDPAAEERFKAVSEAHDVLSDPAKRKEYDET 74
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 3-68 1.55e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 96.23  E-value: 1.55e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFG 68
Cdd:PRK14287   4 RDYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKAPDAEDKFKEVKEAYDTLSDPQKKAHYDQFG 69
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 3-71 3.63e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 95.24  E-value: 3.63e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKN--KSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEG 71
Cdd:PRK14282   4 KDYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHpeNRKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGYVG 74
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 4-62 6.91e-25

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 87.36  E-value: 6.91e-25
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824  4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKRE 62
Cdd:COG5407   1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKgDPKAEERFKEINEAYELLSDAEKRA 60
DnaJ smart00271
DnaJ molecular chaperone homology domain;
3-60 8.54e-25

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 87.29  E-value: 8.54e-25
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824    3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKS--PQAEEKFKEVAEAYEVLSDPKK 60
Cdd:smart00271  1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGdkEEAEEKFKEINEAYEVLSDPEK 60
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
3-66 1.59e-24

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 87.47  E-value: 1.59e-24
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 952977824  3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSP--QAEEKFKEVAEAYEVLSDPKKREIYDQ 66
Cdd:COG2214   5 KDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELkaLAEELFQRLNEAYEVLSDPERRAEYDR 70
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 4-57 2.11e-24

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 86.06  E-value: 2.11e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 952977824  4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKS-PQAEEKFKEVAEAYEVLSD 57
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDdPEAEEKFKEINEAYEVLSD 55
termin_org_DnaJ TIGR03835
terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ ...
 3-72 6.47e-24

terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ homolog and probable assembly protein of the Mycoplasma terminal organelle. The terminal organelle is involved in both cytadherence and gliding motility. [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274808 [Multi-domain]  Cd Length: 871  Bit Score: 92.95  E-value: 6.47e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824    3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:TIGR03835   2 RDYYEVLGIDRDADEQEIKKAFRKLAKKYHPDRNKAPDAASIFAEINEANDVLSNPKKRANYDKYGHDGV 71
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 3-72 2.23e-23

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 91.04  E-value: 2.23e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPqaeEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PTZ00037  28 EKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDP---EKFKEISRAYEVLSDPEKRKIYDEYGEEGL 94
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 1-68 2.33e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 90.44  E-value: 2.33e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFG 68
Cdd:PRK14285   1 MKRDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKgNKEAESIFKEATEAYEVLIDDNKRAQYDRFG 69
PRK10266 PRK10266
curved DNA-binding protein;
3-66 3.27e-23

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 89.11  E-value: 3.27e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQ 66
Cdd:PRK10266   4 KDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQ 67
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 3-68 4.85e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 86.92  E-value: 4.85e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFG 68
Cdd:PRK14296   4 KDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKSPDAHDKMVEINEAADVLLDKDKRKQYDQFG 69
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 1-70 1.40e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 85.84  E-value: 1.40e-21
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEE 70
Cdd:PRK14300   1 MSQDYYQILGVSKTASQADLKKAYLKLAKQYHPDTTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRFGHD 70
PRK14288 PRK14288
molecular chaperone DnaJ;
1-72 5.34e-17

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 73.18  E-value: 5.34e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 952977824   1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PRK14288   1 MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAgDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGL 73
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
4-63 6.06e-15

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 62.51  E-value: 6.06e-15
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 952977824  4 DYYCILGIEKGASDEDIKKAYRKQALKFHPDK---NKSPQ----AEEKFKEVAEAYEVLSDPKKREI 63
Cdd:COG1076   5 DAFELLGLPPDADDAELKRAYRKLQREHHPDRlaaGLPEEeqrlALQKAAAINEAYETLKDPRGIDL 71
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 5-72 1.17e-10

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 55.18  E-value: 1.17e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824    5 YYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGI 72
Cdd:PTZ00341  575 FYDILGVGVNADMKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQILGDIDKKKMYNKFGYDGI 642
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 4-65 4.34e-08

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 48.11  E-value: 4.34e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824   4 DYYCILGIEK---GASDEDIKKAYRKQALKFHPDKNKSPQA---EEKFKEVAEAYEVLSDPKKREIYD 65
Cdd:COG5269   44 DLYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAAGGNkgcDEFFKLIQKAREVLGDRKLRLQYD 111
djlA PRK09430
co-chaperone DjlA;
3-55 1.92e-07

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 45.96  E-value: 1.92e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 952977824   3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDK--NK--SPQ----AEEKFKEVAEAYEVL 55
Cdd:PRK09430 200 EDAYKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvAKglPPEmmemAKEKAQEIQAAYELI 260
PHA03102 PHA03102
Small T antigen; Reviewed
 9-74 4.11e-07

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 44.28  E-value: 4.11e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 952977824   9 LGIEKGA--SDEDIKKAYRKQALKFHPDKNKSpqaEEKFKEVAEAYEVLSDPKKrEIYDQFGEEGIVW 74
Cdd:PHA03102  11 LGLPRSAwgNLPLMRKAYLRKCLEFHPDKGGD---EEKMKELNTLYKKFRESVK-SLRDLDGEEDSSS 74
PHA02624 PHA02624
large T antigen; Provisional
 9-61 8.78e-06

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 41.51  E-value: 8.78e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 952977824   9 LGIEKGA--SDEDIKKAYRKQALKFHPDKNKSpqaEEKFKEVAEAYEVLSDPKKR 61
Cdd:PHA02624  17 LGLPMAAwgNLPLMRKAYLRKCKEYHPDKGGD---EEKMKRLNSLYKKLQEGVKS 68
hscB PRK01356
co-chaperone HscB; Provisional
 4-64 6.77e-04

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 35.62  E-value: 6.77e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 952977824   4 DYYCILGIEKGASD--EDIKKAYRKQALKFHPDKNKSPQAEEKF----KEVAEAYEVLSDPKKREIY 64
Cdd:PRK01356   3 NYFQLLGLPQEYNIdlKILEKQYFAMQVKYHPDKAKTLQEKEQNliiaSELNNAYSTLKDALKRAEY 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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