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cytoplasmic tRNA 2-thiolation protein 2 isoform 4 [Homo sapiens]
cytoplasmic tRNA 2-thiolation protein 2( domain architecture ID 10563289)
cytoplasmic tRNA 2-thiolation protein 2 (CTU2) plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln)
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
CTU2 | pfam10288 | Cytoplasmic tRNA 2-thiolation protein 2; CTU2 is a family of proteins necessary for the ... |
254-381 | 1.45e-28 | |||
Cytoplasmic tRNA 2-thiolation protein 2; CTU2 is a family of proteins necessary for the formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. The family is conserved from plants to humans ]1]. It plays a central role in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine, or the wobble nucleoside. This wobble modification in tRNAs, 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U), is required for the proper decoding of NNR codons in eukaryotes. The 2-thio group gives rigidity by largely fixing the C3'-endo ribose puckering, ensuring stable and accurate codon-anticodon pairing. : Pssm-ID: 463044 Cd Length: 106 Bit Score: 108.28 E-value: 1.45e-28
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TilS super family | cl43000 | tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]; tRNA ... |
157-284 | 8.41e-04 | |||
tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]; tRNA(Ile)-lysidine synthase TilS/MesJ is part of the Pathway/BioSystem: tRNA modification The actual alignment was detected with superfamily member COG0037: Pssm-ID: 439807 [Multi-domain] Cd Length: 235 Bit Score: 40.59 E-value: 8.41e-04
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Name | Accession | Description | Interval | E-value | |||
CTU2 | pfam10288 | Cytoplasmic tRNA 2-thiolation protein 2; CTU2 is a family of proteins necessary for the ... |
254-381 | 1.45e-28 | |||
Cytoplasmic tRNA 2-thiolation protein 2; CTU2 is a family of proteins necessary for the formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. The family is conserved from plants to humans ]1]. It plays a central role in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine, or the wobble nucleoside. This wobble modification in tRNAs, 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U), is required for the proper decoding of NNR codons in eukaryotes. The 2-thio group gives rigidity by largely fixing the C3'-endo ribose puckering, ensuring stable and accurate codon-anticodon pairing. Pssm-ID: 463044 Cd Length: 106 Bit Score: 108.28 E-value: 1.45e-28
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TilS | COG0037 | tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]; tRNA ... |
157-284 | 8.41e-04 | |||
tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]; tRNA(Ile)-lysidine synthase TilS/MesJ is part of the Pathway/BioSystem: tRNA modification Pssm-ID: 439807 [Multi-domain] Cd Length: 235 Bit Score: 40.59 E-value: 8.41e-04
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Name | Accession | Description | Interval | E-value | |||
CTU2 | pfam10288 | Cytoplasmic tRNA 2-thiolation protein 2; CTU2 is a family of proteins necessary for the ... |
254-381 | 1.45e-28 | |||
Cytoplasmic tRNA 2-thiolation protein 2; CTU2 is a family of proteins necessary for the formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. The family is conserved from plants to humans ]1]. It plays a central role in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine, or the wobble nucleoside. This wobble modification in tRNAs, 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U), is required for the proper decoding of NNR codons in eukaryotes. The 2-thio group gives rigidity by largely fixing the C3'-endo ribose puckering, ensuring stable and accurate codon-anticodon pairing. Pssm-ID: 463044 Cd Length: 106 Bit Score: 108.28 E-value: 1.45e-28
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TilS | COG0037 | tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]; tRNA ... |
157-284 | 8.41e-04 | |||
tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]; tRNA(Ile)-lysidine synthase TilS/MesJ is part of the Pathway/BioSystem: tRNA modification Pssm-ID: 439807 [Multi-domain] Cd Length: 235 Bit Score: 40.59 E-value: 8.41e-04
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Blast search parameters | ||||
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