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Conserved domains on  [gi|974141102|ref|NP_001305802|]
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Golgi apparatus membrane protein TVP23 homolog A isoform 2 [Homo sapiens]

Protein Classification

DUF846 domain-containing protein( domain architecture ID 10530749)

DUF846 domain-containing protein similar to Saccharomyces cerevisiae Golgi apparatus membrane protein TVP23 that is involved in vesicular trafficking

Gene Ontology:  GO:0016020|GO:0016192|GO:0009306

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF846 pfam05832
Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown ...
 1-107 1.58e-44

Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown function from a variety of eukaryotic organizms.


:

Pssm-ID: 461754  Cd Length: 139  Bit Score: 142.71  E-value: 1.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974141102    1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARkvsPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLF 80
Cdd:pfam05832  36 IVILLLALDFWTVKNITGRLLVGLRWWNEVDEDGESTWVFESR---DPKRPVNAIDSKLFWLSLYVTPLIWILLLIVAII 112

                          90       100
                  ....*....|....*....|....*..
gi 974141102   81 SLKLKWLALVVAGISLQAANLYGYILC 107
Cdd:pfam05832 113 SLKFFWLLLVIIALVLNGTNLYGFYKC 139
 
Name Accession Description Interval E-value
DUF846 pfam05832
Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown ...
 1-107 1.58e-44

Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown function from a variety of eukaryotic organizms.


Pssm-ID: 461754  Cd Length: 139  Bit Score: 142.71  E-value: 1.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974141102    1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARkvsPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLF 80
Cdd:pfam05832  36 IVILLLALDFWTVKNITGRLLVGLRWWNEVDEDGESTWVFESR---DPKRPVNAIDSKLFWLSLYVTPLIWILLLIVAII 112

                          90       100
                  ....*....|....*....|....*..
gi 974141102   81 SLKLKWLALVVAGISLQAANLYGYILC 107
Cdd:pfam05832 113 SLKFFWLLLVIIALVLNGTNLYGFYKC 139
 
Name Accession Description Interval E-value
DUF846 pfam05832
Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown ...
 1-107 1.58e-44

Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown function from a variety of eukaryotic organizms.


Pssm-ID: 461754  Cd Length: 139  Bit Score: 142.71  E-value: 1.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974141102    1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARkvsPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLF 80
Cdd:pfam05832  36 IVILLLALDFWTVKNITGRLLVGLRWWNEVDEDGESTWVFESR---DPKRPVNAIDSKLFWLSLYVTPLIWILLLIVAII 112

                          90       100
                  ....*....|....*....|....*..
gi 974141102   81 SLKLKWLALVVAGISLQAANLYGYILC 107
Cdd:pfam05832 113 SLKFFWLLLVIIALVLNGTNLYGFYKC 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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