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Conserved domains on  [gi|974141111|ref|NP_001305806|]
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P antigen family member 4 [Homo sapiens]

Protein Classification

GAGE domain-containing protein( domain architecture ID 10530748)

GAGE domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GAGE super family cl05418
GAGE protein; This family consists of several GAGE and XAGE proteins which are found ...
 14-98 1.43e-22

GAGE protein; This family consists of several GAGE and XAGE proteins which are found exclusively in humans. The function of this family is unknown although they have been implicated in human cancers.


The actual alignment was detected with superfamily member pfam05831:

Pssm-ID: 461753  Cd Length: 107  Bit Score: 83.97  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974141111   14 DGQEAPDVVAFVAPGE-----SQQEEPPTDNQDIEPGQER--EGTPPIEERKVEGDCQEMDLEKTRSERGDGSDVKEKTP 86
Cdd:pfam05831  16 DDQESSQLVGPVVAQQpsdeqPQQEEPPTESQDITPGQERedEGASAIQGPELEADLQELALEKTGGERGDGPDVKGKTL 95

                          90
                  ....*....|..
gi 974141111   87 PNPKHAKTKEAG 98
Cdd:pfam05831  96 PNLEPVKMPEAG 107
 
Name Accession Description Interval E-value
GAGE pfam05831
GAGE protein; This family consists of several GAGE and XAGE proteins which are found ...
 14-98 1.43e-22

GAGE protein; This family consists of several GAGE and XAGE proteins which are found exclusively in humans. The function of this family is unknown although they have been implicated in human cancers.


Pssm-ID: 461753  Cd Length: 107  Bit Score: 83.97  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974141111   14 DGQEAPDVVAFVAPGE-----SQQEEPPTDNQDIEPGQER--EGTPPIEERKVEGDCQEMDLEKTRSERGDGSDVKEKTP 86
Cdd:pfam05831  16 DDQESSQLVGPVVAQQpsdeqPQQEEPPTESQDITPGQERedEGASAIQGPELEADLQELALEKTGGERGDGPDVKGKTL 95

                          90
                  ....*....|..
gi 974141111   87 PNPKHAKTKEAG 98
Cdd:pfam05831  96 PNLEPVKMPEAG 107
 
Name Accession Description Interval E-value
GAGE pfam05831
GAGE protein; This family consists of several GAGE and XAGE proteins which are found ...
 14-98 1.43e-22

GAGE protein; This family consists of several GAGE and XAGE proteins which are found exclusively in humans. The function of this family is unknown although they have been implicated in human cancers.


Pssm-ID: 461753  Cd Length: 107  Bit Score: 83.97  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974141111   14 DGQEAPDVVAFVAPGE-----SQQEEPPTDNQDIEPGQER--EGTPPIEERKVEGDCQEMDLEKTRSERGDGSDVKEKTP 86
Cdd:pfam05831  16 DDQESSQLVGPVVAQQpsdeqPQQEEPPTESQDITPGQERedEGASAIQGPELEADLQELALEKTGGERGDGPDVKGKTL 95

                          90
                  ....*....|..
gi 974141111   87 PNPKHAKTKEAG 98
Cdd:pfam05831  96 PNLEPVKMPEAG 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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