tectonic-1 isoform 8 [Homo sapiens]
tectonic family protein( domain architecture ID 10405)
tectonic family protein, formerly called DUF1619 domain, similar to Homo sapiens tectonic proteins which are components of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes, and is required for hedgehog signaling transduction
List of domain hits
Name | Accession | Description | Interval | E-value | |||
TCTN_DUF1619 super family | cl06690 | Tectonic domain DUF1619; This is a conserved domain found in tectonic proteins (TCTN1/2/3) ... |
22-153 | 9.99e-43 | |||
Tectonic domain DUF1619; This is a conserved domain found in tectonic proteins (TCTN1/2/3) which contains a Cys rich N-terminal region. Although its function is currently unknown (this domain is also known as DUF1619), studies in TCTN2 suggest that it is indispensable for normal functions. These proteins form a complex required for hedgehog signalling transduction. The actual alignment was detected with superfamily member pfam07773: Pssm-ID: 462260 Cd Length: 315 Bit Score: 145.00 E-value: 9.99e-43
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Name | Accession | Description | Interval | E-value | |||
TCTN_DUF1619 | pfam07773 | Tectonic domain DUF1619; This is a conserved domain found in tectonic proteins (TCTN1/2/3) ... |
22-153 | 9.99e-43 | |||
Tectonic domain DUF1619; This is a conserved domain found in tectonic proteins (TCTN1/2/3) which contains a Cys rich N-terminal region. Although its function is currently unknown (this domain is also known as DUF1619), studies in TCTN2 suggest that it is indispensable for normal functions. These proteins form a complex required for hedgehog signalling transduction. Pssm-ID: 462260 Cd Length: 315 Bit Score: 145.00 E-value: 9.99e-43
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Name | Accession | Description | Interval | E-value | |||
TCTN_DUF1619 | pfam07773 | Tectonic domain DUF1619; This is a conserved domain found in tectonic proteins (TCTN1/2/3) ... |
22-153 | 9.99e-43 | |||
Tectonic domain DUF1619; This is a conserved domain found in tectonic proteins (TCTN1/2/3) which contains a Cys rich N-terminal region. Although its function is currently unknown (this domain is also known as DUF1619), studies in TCTN2 suggest that it is indispensable for normal functions. These proteins form a complex required for hedgehog signalling transduction. Pssm-ID: 462260 Cd Length: 315 Bit Score: 145.00 E-value: 9.99e-43
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Blast search parameters | ||||
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