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Conserved domains on  [gi|992319628|ref|NP_001307065|]
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DNA fragmentation factor subunit beta isoform 5 [Homo sapiens]

Protein Classification

DFF40 domain-containing protein( domain architecture ID 10557919)

DFF40 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DFF40 pfam09230
DNA fragmentation factor 40 kDa; Members of this family of eukaryotic apoptotic proteins ...
36-259 1.08e-150

DNA fragmentation factor 40 kDa; Members of this family of eukaryotic apoptotic proteins induce DNA fragmentation and chromatin condensation during apoptosis.


:

Pssm-ID: 462717  Cd Length: 226  Bit Score: 419.78  E-value: 1.08e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992319628   36 IQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTV- 114
Cdd:pfam09230   1 IEAARQLLSDENAPERQKLLADLLHNLDENIEAETREEDPDWFEGLESRFKTKSEYMRYSCQSRIRGYFYEVKEYLTKCa 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992319628  115 GAEAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSNRESRILFSTWNL 194
Cdd:pfam09230  81 NAKAREEYLKVLESFRELLKGFDYNGSYFDRSEKESVRLCTPEGWFSCQGPFDEESCSSLHSINPYGSRESRILFSTWNL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 992319628  195 DHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLKLVHIVCHKKTTH-KLNCDPSRIYK 259
Cdd:pfam09230 161 DHRIEKKRTILPALVEAVENQKGRELNWEYFYRLLFTLENLKLVHIVCHKKTAHdGLSCDPCKIYK 226
 
Name Accession Description Interval E-value
DFF40 pfam09230
DNA fragmentation factor 40 kDa; Members of this family of eukaryotic apoptotic proteins ...
36-259 1.08e-150

DNA fragmentation factor 40 kDa; Members of this family of eukaryotic apoptotic proteins induce DNA fragmentation and chromatin condensation during apoptosis.


Pssm-ID: 462717  Cd Length: 226  Bit Score: 419.78  E-value: 1.08e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992319628   36 IQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTV- 114
Cdd:pfam09230   1 IEAARQLLSDENAPERQKLLADLLHNLDENIEAETREEDPDWFEGLESRFKTKSEYMRYSCQSRIRGYFYEVKEYLTKCa 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992319628  115 GAEAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSNRESRILFSTWNL 194
Cdd:pfam09230  81 NAKAREEYLKVLESFRELLKGFDYNGSYFDRSEKESVRLCTPEGWFSCQGPFDEESCSSLHSINPYGSRESRILFSTWNL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 992319628  195 DHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLKLVHIVCHKKTTH-KLNCDPSRIYK 259
Cdd:pfam09230 161 DHRIEKKRTILPALVEAVENQKGRELNWEYFYRLLFTLENLKLVHIVCHKKTAHdGLSCDPCKIYK 226
 
Name Accession Description Interval E-value
DFF40 pfam09230
DNA fragmentation factor 40 kDa; Members of this family of eukaryotic apoptotic proteins ...
36-259 1.08e-150

DNA fragmentation factor 40 kDa; Members of this family of eukaryotic apoptotic proteins induce DNA fragmentation and chromatin condensation during apoptosis.


Pssm-ID: 462717  Cd Length: 226  Bit Score: 419.78  E-value: 1.08e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992319628   36 IQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTV- 114
Cdd:pfam09230   1 IEAARQLLSDENAPERQKLLADLLHNLDENIEAETREEDPDWFEGLESRFKTKSEYMRYSCQSRIRGYFYEVKEYLTKCa 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992319628  115 GAEAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSNRESRILFSTWNL 194
Cdd:pfam09230  81 NAKAREEYLKVLESFRELLKGFDYNGSYFDRSEKESVRLCTPEGWFSCQGPFDEESCSSLHSINPYGSRESRILFSTWNL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 992319628  195 DHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLKLVHIVCHKKTTH-KLNCDPSRIYK 259
Cdd:pfam09230 161 DHRIEKKRTILPALVEAVENQKGRELNWEYFYRLLFTLENLKLVHIVCHKKTAHdGLSCDPCKIYK 226
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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