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Conserved domains on  [gi|998614208|ref|NP_001307251|]
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protein O-mannosyl-transferase TMTC2 isoform 3 precursor [Homo sapiens]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 247-318 5.60e-36

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


:

Pssm-ID: 462468  Cd Length: 75  Bit Score: 129.57  E-value: 5.60e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 998614208  247 GNKPPSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYT 318
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYG 72
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
473-623 2.07e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.39  E-value: 2.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG0457   20 RLGRYEEAIEDYEKALELDPddAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDY 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 998614208 551 KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG0457  100 DKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL---DPDDADAL--------YNLGIALEKLGRYE 161
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 247-318 5.60e-36

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 129.57  E-value: 5.60e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 998614208  247 GNKPPSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYT 318
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYG 72
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
473-623 2.07e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.39  E-value: 2.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG0457   20 RLGRYEEAIEDYEKALELDPddAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDY 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 998614208 551 KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG0457  100 DKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL---DPDDADAL--------YNLGIALEKLGRYE 161
TPR_12 pfam13424
Tetratricopeptide repeat;
526-590 1.01e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 1.01e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 998614208  526 MADMLYNLGLLLQENSRFAEALHYYKLAI--------GSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI 590
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALeiarrllgPDHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 510-620 5.24e-07

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 50.06  E-value: 5.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 510 SEAESAYrnaLYYRSNMAdmlynlgllLQENSRFAEALHYYK--LAIGSRPTLASAYL-NTGIILMNQGRTEEARRTFLK 586
Cdd:PRK02603  30 KKAKEAF---VYYRDGMS---------AQADGEYAEALENYEeaLKLEEDPNDRSYILyNMGIIYASNGEHDKALEYYHQ 97

                         90       100       110
                 ....*....|....*....|....*....|....
gi 998614208 587 CSEipdENLKDPhahkssvtSCLYNLGKLYHEQG 620
Cdd:PRK02603  98 ALE---LNPKQP--------SALNNIAVIYHKRG 120
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 473-594 1.10e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208  473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRfAEALHYY 550
Cdd:TIGR02917 748 ASGNTAEAVKTLEAWLKTHPndAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYA 826

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 998614208  551 KLAIGSRPTLAsAYLNT-GIILMNQGRTEEARRTFLKCSEIPDEN 594
Cdd:TIGR02917 827 ERALKLAPNIP-AILDTlGWLLVEKGEADRALPLLRKAVNIAPEA 870
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 530-594 2.32e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 2.32e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 998614208 530 LYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI-PDEN 594
Cdd:cd24142    3 LLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELdPDGG 68
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 493-520 3.90e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 3.90e-03
                           10        20
                   ....*....|....*....|....*...
gi 998614208   493 AKAWGNLGNVLKSQSKISEAESAYRNAL 520
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKAL 28
 
Name Accession Description Interval E-value
TMTC_DUF1736 pfam08409
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ...
 247-318 5.60e-36

Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3.


Pssm-ID: 462468  Cd Length: 75  Bit Score: 129.57  E-value: 5.60e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 998614208  247 GNKPPSFSNSDNPAADSDSLLTRTLTFFYLPTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYT 318
Cdd:pfam08409   1 GGQLPVFSASDNPAAFSPSLLTRTLTYNYLPALNAWLLLFPSWLCFDWSMGSIPLIESLSDPRNLATLAFYG 72
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
473-623 2.07e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.39  E-value: 2.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG0457   20 RLGRYEEAIEDYEKALELDPddAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDY 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 998614208 551 KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG0457  100 DKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL---DPDDADAL--------YNLGIALEKLGRYE 161
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 473-596 6.03e-23

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 103.53  E-value: 6.03e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG3914   90 ALGRYEEALALYRRALALNPdnAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAAL 169

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 998614208 551 KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLK 596
Cdd:COG3914  170 RRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
488-623 6.10e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.16  E-value: 6.10e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 488 IKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYL 565
Cdd:COG0457    1 LELDPddAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 998614208 566 NTGIILMNQGRTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALEL---DPDDAEAL--------YNLGLALLELGRYD 127
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
475-586 3.92e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 87.37  E-value: 3.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 475 GDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKL 552
Cdd:COG0457   56 GRYEEALADYEQALELDPddAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135

                         90       100       110
                 ....*....|....*....|....*....|....
gi 998614208 553 AIGSRPTLASAYLNTGIILMNQGRTEEARRTFLK 586
Cdd:COG0457  136 ALELDPDDADALYNLGIALEKLGRYEEALELLEK 169
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 499-623 2.01e-16

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 83.12  E-value: 2.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 499 LGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTE 578
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 998614208 579 EARRTFLKCSEI-PDenlkDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG3914  164 EAIAALRRALELdPD----NAEAL--------NNLGNALQDLGRLE 197
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 469-594 4.85e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 72.53  E-value: 4.85e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 469 KTAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEA 546
Cdd:COG4783   12 QALLLAGDYDEAEALLEKALELDPdnPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEA 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 998614208 547 LHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDEN 594
Cdd:COG4783   92 LALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 472-623 1.43e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 1.43e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 472 IRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHY 549
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPddAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 998614208 550 YKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIpdenlkDPHAhkssvTSCLYNLGKLYHEQGHYE 623
Cdd:COG2956  167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ------DPDY-----LPALPRLAELYEKLGDPE 229
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 470-582 1.78e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.57  E-value: 1.78e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 470 TAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEAL 547
Cdd:COG3914  121 LLLALGRLEEALAALRRALALNPdfAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAI 200

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 998614208 548 HYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARR 582
Cdd:COG3914  201 AAYRRALELDPDNADAHSNLLFALRQACDWEVYDR 235
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 457-586 1.93e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 71.14  E-value: 1.93e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 457 YATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLL 536
Cdd:COG5010   18 TKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALL 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 998614208 537 LQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLK 586
Cdd:COG5010   98 YSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 484-594 3.49e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 66.95  E-value: 3.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 484 YRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLA 561
Cdd:COG4235    6 LRQALAANPndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100       110
                 ....*....|....*....|....*....|...
gi 998614208 562 SAYLNTGIILMNQGRTEEARRTFLKCSEIPDEN 594
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
493-601 8.69e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 68.02  E-value: 8.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 493 AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILM 572
Cdd:COG4785   73 AQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALY 152

                         90       100
                 ....*....|....*....|....*....
gi 998614208 573 NQGRTEEARRTFLKCSEipdENLKDPHAH 601
Cdd:COG4785  153 YLGRYELAIADLEKALE---LDPNDPERA 178
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
502-596 1.14e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 64.04  E-value: 1.14e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 502 VLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKlAIGSRPTLASAYLNTGIILMNQGRTEEAR 581
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....*
gi 998614208 582 RTFLKCSEIPDENLK 596
Cdd:COG3063   80 AYLERALELDPSALR 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 473-623 1.15e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.60  E-value: 1.15e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG2956   54 RRGEYDRAIRIHQKLLERDPdrAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVL 133

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 998614208 551 KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIpdenlkDPHAHKSsvtscLYNLGKLYHEQGHYE 623
Cdd:COG2956  134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL------DPDCARA-----LLLLAELYLEQGDYE 195
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 454-623 2.20e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 2.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 454 LIFYATATLIVFYGLKtAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLY 531
Cdd:COG2956    2 LLPVAAALGWYFKGLN-YLLNGQPDKAIDLLEEALELDPetVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 532 NLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENlkdPHAHkssvtsclYN 611
Cdd:COG2956   81 ELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---AHAY--------CE 149

                        170
                 ....*....|..
gi 998614208 612 LGKLYHEQGHYE 623
Cdd:COG2956  150 LAELYLEQGDYD 161
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 493-623 4.83e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.67  E-value: 4.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 493 AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILM 572
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 998614208 573 NQGRTEEARRTFLKCSEIpdeNLKDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG4783   84 KAGDYDEALALLEKALKL---DPEHPEAY--------LRLARAYRALGRPD 123
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 439-623 1.05e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.91  E-value: 1.05e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 439 ARALYVKVQKRFLKSLifYATATLIVFYglktaIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAY 516
Cdd:COG2956   95 AEELLEKLLELDPDDA--EALRLLAEIY-----EQEGDWEKAIEVLERLLKLGPenAHAYCELAELYLEQGDYDEAIEAL 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 517 RNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENlk 596
Cdd:COG2956  168 EKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-- 245

                        170       180
                 ....*....|....*....|....*..
gi 998614208 597 dphahkssvtSCLYNLGKLYHEQGHYE 623
Cdd:COG2956  246 ----------DLLLALADLLERKEGLE 262
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
471-560 4.01e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.80  E-value: 4.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 471 AIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAEsAYRNALYYRSNMADMLYNLGLLLQENSRFAEALH 548
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPdnADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|..
gi 998614208 549 YYKLAIGSRPTL 560
Cdd:COG3063   81 YLERALELDPSA 92
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 511-623 5.90e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.40  E-value: 5.90e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 511 EAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI 590
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 998614208 591 -PDenlkDPHAhkssvtscLYNLGKLYHEQGHYE 623
Cdd:COG4235   81 dPD----NPEA--------LYLLGLAAFQQGDYA 102
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 439-558 9.39e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 60.74  E-value: 9.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 439 ARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAY 516
Cdd:COG5010   32 AGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPnnPELYYNLALLYSRSGDKDEAKEYY 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 998614208 517 RNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRP 558
Cdd:COG5010  112 EKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 511-623 3.06e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.20  E-value: 3.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 511 EAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI 590
Cdd:COG5010   38 KEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL 117

                         90       100       110
                 ....*....|....*....|....*....|...
gi 998614208 591 PDENlkdPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG5010  118 SPDN---PNAY--------SNLAALLLSLGQDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 512-623 1.89e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.78  E-value: 1.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 512 AESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIP 591
Cdd:COG3914   63 AAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN 142

                         90       100       110
                 ....*....|....*....|....*....|..
gi 998614208 592 DENlkdPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG3914  143 PDF---AEAY--------LNLGEALRRLGRLE 163
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 524-623 3.06e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.58  E-value: 3.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 524 SNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI-PDEnlkdPHAHk 602
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELdPDE----PEAR- 75

                         90       100
                 ....*....|....*....|.
gi 998614208 603 ssvtsclYNLGKLYHEQGHYE 623
Cdd:COG4783   76 -------LNLGLALLKAGDYD 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
536-623 3.69e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.02  E-value: 3.69e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 536 LLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRtFLKCSEIpdeNLKDPHAhkssvtscLYNLGKL 615
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKL---DPNNAEA--------LLNLAEL 68


                 ....*...
gi 998614208 616 YHEQGHYE 623
Cdd:COG3063   69 LLELGDYD 76
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 469-586 3.92e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 3.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 469 KTAIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEA 546
Cdd:COG2956  152 ELYLEQGDYDEAIEALEKALKLDPdcARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 998614208 547 LHYYKLAIGSRPTLaSAYLNTGIILMNQGRTEEARRTFLK 586
Cdd:COG2956  232 LELLRKALELDPSD-DLLLALADLLERKEGLEAALALLER 270
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
475-582 3.96e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 3.96e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 475 GDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKL 552
Cdd:COG0457   90 GRYEEALEDYDKALELDPddAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEK 169

                         90       100       110
                 ....*....|....*....|....*....|
gi 998614208 553 AIGSRPTLASAYLNTGIILMNQGRTEEARR 582
Cdd:COG0457  170 LEAAALAALLAAALGEAALALAAAEVLLAL 199
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 506-584 9.80e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 50.76  E-value: 9.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 506 QSKISEAESAYRNAL--YYRSNMA-DMLYNLGLLLQENSRFAEALHYYKLAIGSRPT---LASAYLNTGIILMNQGRTEE 579
Cdd:COG1729    6 AGDYDEAIAAFKAFLkrYPNSPLApDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDK 85


                 ....*
gi 998614208 580 ARRTF 584
Cdd:COG1729   86 ARATL 90
TPR_12 pfam13424
Tetratricopeptide repeat;
526-590 1.01e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 49.69  E-value: 1.01e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 998614208  526 MADMLYNLGLLLQENSRFAEALHYYKLAI--------GSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI 590
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALeiarrllgPDHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 510-620 5.24e-07

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 50.06  E-value: 5.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 510 SEAESAYrnaLYYRSNMAdmlynlgllLQENSRFAEALHYYK--LAIGSRPTLASAYL-NTGIILMNQGRTEEARRTFLK 586
Cdd:PRK02603  30 KKAKEAF---VYYRDGMS---------AQADGEYAEALENYEeaLKLEEDPNDRSYILyNMGIIYASNGEHDKALEYYHQ 97

                         90       100       110
                 ....*....|....*....|....*....|....
gi 998614208 587 CSEipdENLKDPhahkssvtSCLYNLGKLYHEQG 620
Cdd:PRK02603  98 ALE---LNPKQP--------SALNNIAVIYHKRG 120
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 473-565 6.88e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 6.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG4235   29 RLGRYDEALAAYEKALRLDPdnADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAW 108

                         90
                 ....*....|....*
gi 998614208 551 KLAIGSRPTLASAYL 565
Cdd:COG4235  109 QKLLALLPADAPARL 123
TPR_12 pfam13424
Tetratricopeptide repeat;
560-623 3.66e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 3.66e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 998614208  560 LASAYLNTGIILMNQGRTEEARRTFLKCSEIpDENLKDPHaHKSSVTScLYNLGKLYHEQGHYE 623
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEI-ARRLLGPD-HPLTATT-LLNLGRLYLELGRYE 62
TPR_12 pfam13424
Tetratricopeptide repeat;
493-554 8.02e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 44.30  E-value: 8.02e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208  493 AKAWGNLGNVLKSQSKISEAESAYRNALY--------YRSNMADMLYNLGLLLQENSRFAEALHYYKLAI 554
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEiarrllgpDHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 510-589 8.90e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 46.59  E-value: 8.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 510 SEAESAYRNALYYRSNMAD---MLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRT-------EE 579
Cdd:PRK02603  52 AEALENYEEALKLEEDPNDrsyILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEKaeeagdqDE 131

                         90
                 ....*....|
gi 998614208 580 ARRTFLKCSE 589
Cdd:PRK02603 132 AEALFDKAAE 141
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
512-623 1.10e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.83  E-value: 1.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 512 AESAYRNALYYRsNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI- 590
Cdd:COG4785   59 AAERIDRALALP-DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELd 137

                         90       100       110
                 ....*....|....*....|....*....|...
gi 998614208 591 PDenlkDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG4785  138 PD----YAYAY--------LNRGIALYYLGRYE 158
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 469-554 2.78e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 2.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 469 KTAIRNGDWQNEEMLYRSGIKVNP-----AKAWGNLGNVLKSQSKISEAESAYRNALYYRSN---MADMLYNLGLLLQEN 540
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYPnsplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLEL 80

                         90
                 ....*....|....
gi 998614208 541 SRFAEALHYYKLAI 554
Cdd:COG1729   81 GDYDKARATLEELI 94
ycf3 CHL00033
photosystem I assembly protein Ycf3
 505-589 3.94e-05

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 44.61  E-value: 3.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 505 SQSKISEAESAYRNALYYRSNMAD---MLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGII-------LMNQ 574
Cdd:CHL00033  47 SEGEYAEALQNYYEAMRLEIDPYDrsyILYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVIchyrgeqAIEQ 126

                         90
                 ....*....|....*
gi 998614208 575 GRTEEARRTFLKCSE 589
Cdd:CHL00033 127 GDSEIAEAWFDQAAE 141
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 531-586 6.77e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 6.77e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 998614208  531 YNLGLLLQENSRFAEALHYYKLAIGSRPTL---ASAYLNTGIILMNQGRTEEARRTFLK 586
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESpdaAAALLLLGLAALRQGRLAEAAAAYRA 59
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 539-623 7.92e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 42.29  E-value: 7.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 539 ENSRFAEALHYYKLAIGSRPT---LASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAhkssvtscLYNLGKL 615
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDA--------LLKLGLS 76


                 ....*...
gi 998614208 616 YHEQGHYE 623
Cdd:COG1729   77 YLELGDYD 84
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 473-594 1.10e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208  473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRfAEALHYY 550
Cdd:TIGR02917 748 ASGNTAEAVKTLEAWLKTHPndAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYA 826

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 998614208  551 KLAIGSRPTLAsAYLNT-GIILMNQGRTEEARRTFLKCSEIPDEN 594
Cdd:TIGR02917 827 ERALKLAPNIP-AILDTlGWLLVEKGEADRALPLLRKAVNIAPEA 870
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 512-623 1.52e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 512 AESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIp 591
Cdd:COG5010    5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL- 83

                         90       100       110
                 ....*....|....*....|....*....|..
gi 998614208 592 deNLKDPHAHkssvtsclYNLGKLYHEQGHYE 623
Cdd:COG5010   84 --DPNNPELY--------YNLALLYSRSGDKD 105
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 498-558 2.45e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.63  E-value: 2.45e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 998614208  498 NLGNVLKSQSKISEAESAYRNAL---YYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRP 558
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
473-584 2.71e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 2.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 473 RNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Cdd:COG4785   85 SLGDYDLAIADFDQALELDPdlAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADL 164

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 998614208 551 KLAIGSRPTLASAYLNTGII--------------------LMNQGRTEEARRTF 584
Cdd:COG4785  165 EKALELDPNDPERALWLYLAerkldpekalallledwataYLLQGDTEEARELF 218
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 492-584 6.57e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 6.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208  492 PAKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIIL 571
Cdd:TIGR02917 192 NVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD 271

                          90
                  ....*....|...
gi 998614208  572 MNQGRTEEARRTF 584
Cdd:TIGR02917 272 FQKKNYEDARETL 284
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 471-583 8.14e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 8.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208  471 AIRNGDWQNEEMLYRSGIKVNP--AKAWGNLGNVLKsQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALH 548
Cdd:TIGR02917 780 YLAQKDYDKAIKHYQTVVKKAPdnAVVLNNLAWLYL-ELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALP 858

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 998614208  549 YYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRT 583
Cdd:TIGR02917 859 LLRKAVNIAPEAAAIRYHLALALLATGRKAEARKE 893
TPR_1 pfam00515
Tetratricopeptide repeat;
493-520 9.81e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 9.81e-04
                          10        20
                  ....*....|....*....|....*...
gi 998614208  493 AKAWGNLGNVLKSQSKISEAESAYRNAL 520
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKAL 28
TPR_19 pfam14559
Tetratricopeptide repeat;
542-602 1.00e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 1.00e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 998614208  542 RFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFlkcSEIPDENLKDPHAHK 602
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALL---AALPAADPDDPRYAA 60
COG3899 COG3899
Predicted ATPase [General function prediction only];
510-623 1.91e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.38  E-value: 1.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208  510 SEAESAYRNALYYRsnMADMLYNLGlllqensRFAEALHYYKLA-------------IGSRPTLASAYLNTGIILMnqGR 576
Cdd:COG3899   737 PDPEEEYRLALLLE--LAEALYLAG-------RFEEAEALLERAlaaralaalaalrHGNPPASARAYANLGLLLL--GD 805

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 998614208  577 TEEARRTFLKCSEIPDEnlkdpHAHKSSVTSCLYNLGKLYHEQGHYE 623
Cdd:COG3899   806 YEEAYEFGELALALAER-----LGDRRLEARALFNLGFILHWLGPLR 847
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 530-594 2.32e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 2.32e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 998614208 530 LYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI-PDEN 594
Cdd:cd24142    3 LLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELdPDGG 68
TPR_1 pfam00515
Tetratricopeptide repeat;
527-554 2.84e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 2.84e-03
                          10        20
                  ....*....|....*....|....*...
gi 998614208  527 ADMLYNLGLLLQENSRFAEALHYYKLAI 554
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKAL 28
TPR_11 pfam13414
TPR repeat;
500-540 2.89e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.91  E-value: 2.89e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 998614208  500 GNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQEN 540
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 493-520 3.90e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 3.90e-03
                           10        20
                   ....*....|....*....|....*...
gi 998614208   493 AKAWGNLGNVLKSQSKISEAESAYRNAL 520
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKAL 28
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 511-623 4.44e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.98  E-value: 4.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 998614208 511 EAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEI 590
Cdd:COG3914   28 LAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALAL 107

                         90       100       110
                 ....*....|....*....|....*....|...
gi 998614208 591 pdenlkDPHAHKSsvtscLYNLGKLYHEQGHYE 623
Cdd:COG3914  108 ------NPDNAEA-----LFNLGNLLLALGRLE 129
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 523-584 6.40e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.12  E-value: 6.40e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 998614208 523 RSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTlASAYLNTGIILMNQGRTEEARRTF 584
Cdd:COG3071  254 HPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHY 314
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 527-554 8.49e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 8.49e-03
                           10        20
                   ....*....|....*....|....*...
gi 998614208   527 ADMLYNLGLLLQENSRFAEALHYYKLAI 554
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKAL 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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