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Conserved domains on  [gi|1013071050|ref|NP_001308850|]
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protein FAM219B isoform a [Homo sapiens]

Protein Classification

FAM219A domain-containing protein( domain architecture ID 10633719)

FAM219A domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM219A super family cl21117
Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This ...
 72-198 5.38e-58

Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This protein family has been found in eukaryotes. Proteins in this family are typically between 144 and 191 amino acids in length. There are two conserved sequence motifs: QLL and LDE.


The actual alignment was detected with superfamily member pfam15260:

Pssm-ID: 464600  Cd Length: 124  Bit Score: 178.48  E-value: 5.38e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013071050  72 QKHRDLAKAVLRRKGML-GASPNRPDSSGKRSVKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEqVNQDVS 150
Cdd:pfam15260   1 QKHRELAKAALRKKGLLgGAVLQQPRSGAKRSVKFNKGYTALSQSPEENLVSLDSDSDGELESRYSSGYSSAE-VNQDLS 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1013071050 151 RQLLQDGYHLDEIPDDEDLDLIPPKPMAsstCSCCWCCLGDSSSCTLQ 198
Cdd:pfam15260  80 RQLLQDGYHLDEIPDDEDLDLIPPKPMG---SSTCACCLGESSSCTIQ 124
 
Name Accession Description Interval E-value
FAM219A pfam15260
Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This ...
 72-198 5.38e-58

Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This protein family has been found in eukaryotes. Proteins in this family are typically between 144 and 191 amino acids in length. There are two conserved sequence motifs: QLL and LDE.


Pssm-ID: 464600  Cd Length: 124  Bit Score: 178.48  E-value: 5.38e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013071050  72 QKHRDLAKAVLRRKGML-GASPNRPDSSGKRSVKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEqVNQDVS 150
Cdd:pfam15260   1 QKHRELAKAALRKKGLLgGAVLQQPRSGAKRSVKFNKGYTALSQSPEENLVSLDSDSDGELESRYSSGYSSAE-VNQDLS 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1013071050 151 RQLLQDGYHLDEIPDDEDLDLIPPKPMAsstCSCCWCCLGDSSSCTLQ 198
Cdd:pfam15260  80 RQLLQDGYHLDEIPDDEDLDLIPPKPMG---SSTCACCLGESSSCTIQ 124
 
Name Accession Description Interval E-value
FAM219A pfam15260
Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This ...
 72-198 5.38e-58

Protein family FAM219A; This protein family, FAM219A is a domain of unknown function. This protein family has been found in eukaryotes. Proteins in this family are typically between 144 and 191 amino acids in length. There are two conserved sequence motifs: QLL and LDE.


Pssm-ID: 464600  Cd Length: 124  Bit Score: 178.48  E-value: 5.38e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013071050  72 QKHRDLAKAVLRRKGML-GASPNRPDSSGKRSVKFNKGYTALSQSPDENLVSLDSDSDGELGSRYSSGYSSAEqVNQDVS 150
Cdd:pfam15260   1 QKHRELAKAALRKKGLLgGAVLQQPRSGAKRSVKFNKGYTALSQSPEENLVSLDSDSDGELESRYSSGYSSAE-VNQDLS 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1013071050 151 RQLLQDGYHLDEIPDDEDLDLIPPKPMAsstCSCCWCCLGDSSSCTLQ 198
Cdd:pfam15260  80 RQLLQDGYHLDEIPDDEDLDLIPPKPMG---SSTCACCLGESSSCTIQ 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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