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Conserved domains on  [gi|1016470471|ref|NP_001309238|]
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phosphatase and actin regulator 1 isoform a [Homo sapiens]

Protein Classification

RPEL repeat-containing protein( domain architecture ID 10499653)

RPEL repeat-containing protein such as Phactrs 1-4, a family of protein phosphatase 1 and actin regulatory proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
461-485 4.52e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 4.52e-06
                           10        20
                   ....*....|....*....|....*
gi 1016470471  461 KLTRRLSQRPTAEELEQRNILKPRN 485
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
498-523 2.16e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 41.31  E-value: 2.16e-05
                           10        20
                   ....*....|....*....|....*.
gi 1016470471  498 RRLTRKLSQRPTVEELRERKILIRFS 523
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 140-161 4.18e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


:

Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.33  E-value: 4.18e-05
                          10        20
                  ....*....|....*....|..
gi 1016470471 140 LERKISMRQSREELIKRGVLKE 161
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 423-444 9.45e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


:

Pssm-ID: 460677  Cd Length: 24  Bit Score: 36.48  E-value: 9.45e-04
                          10        20
                  ....*....|....*....|..
gi 1016470471 423 SLAIKLSNRPSKRELEEKNILP 444
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
461-485 4.52e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 4.52e-06
                           10        20
                   ....*....|....*....|....*
gi 1016470471  461 KLTRRLSQRPTAEELEQRNILKPRN 485
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 461-483 8.23e-06

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 42.65  E-value: 8.23e-06
                          10        20
                  ....*....|....*....|...
gi 1016470471 461 KLTRRLSQRPTAEELEQRNILKP 483
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
498-523 2.16e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 41.31  E-value: 2.16e-05
                           10        20
                   ....*....|....*....|....*.
gi 1016470471  498 RRLTRKLSQRPTVEELRERKILIRFS 523
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 140-161 4.18e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.33  E-value: 4.18e-05
                          10        20
                  ....*....|....*....|..
gi 1016470471 140 LERKISMRQSREELIKRGVLKE 161
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 499-519 6.08e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 6.08e-04
                          10        20
                  ....*....|....*....|.
gi 1016470471 499 RLTRKLSQRPTVEELRERKIL 519
Cdd:pfam02755   1 SLERKLSHRPTREELVERNIL 21
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 423-444 9.45e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 36.48  E-value: 9.45e-04
                          10        20
                  ....*....|....*....|..
gi 1016470471 423 SLAIKLSNRPSKRELEEKNILP 444
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
422-446 1.02e-03

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 36.69  E-value: 1.02e-03
                           10        20
                   ....*....|....*....|....*
gi 1016470471  422 DSLAIKLSNRPSKRELEEKNILPRQ 446
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKEL 25
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
140-161 3.32e-03

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 35.15  E-value: 3.32e-03
                           10        20
                   ....*....|....*....|..
gi 1016470471  140 LERKISMRQSREELIKRGVLKE 161
Cdd:smart00707   3 LNRKLSQRPTREELEERNILKE 24
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
461-485 4.52e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.23  E-value: 4.52e-06
                           10        20
                   ....*....|....*....|....*
gi 1016470471  461 KLTRRLSQRPTAEELEQRNILKPRN 485
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 461-483 8.23e-06

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 42.65  E-value: 8.23e-06
                          10        20
                  ....*....|....*....|...
gi 1016470471 461 KLTRRLSQRPTAEELEQRNILKP 483
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
498-523 2.16e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 41.31  E-value: 2.16e-05
                           10        20
                   ....*....|....*....|....*.
gi 1016470471  498 RRLTRKLSQRPTVEELRERKILIRFS 523
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 140-161 4.18e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.33  E-value: 4.18e-05
                          10        20
                  ....*....|....*....|..
gi 1016470471 140 LERKISMRQSREELIKRGVLKE 161
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 499-519 6.08e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 6.08e-04
                          10        20
                  ....*....|....*....|.
gi 1016470471 499 RLTRKLSQRPTVEELRERKIL 519
Cdd:pfam02755   1 SLERKLSHRPTREELVERNIL 21
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 423-444 9.45e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 36.48  E-value: 9.45e-04
                          10        20
                  ....*....|....*....|..
gi 1016470471 423 SLAIKLSNRPSKRELEEKNILP 444
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
422-446 1.02e-03

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 36.69  E-value: 1.02e-03
                           10        20
                   ....*....|....*....|....*
gi 1016470471  422 DSLAIKLSNRPSKRELEEKNILPRQ 446
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKEL 25
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
140-161 3.32e-03

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 35.15  E-value: 3.32e-03
                           10        20
                   ....*....|....*....|..
gi 1016470471  140 LERKISMRQSREELIKRGVLKE 161
Cdd:smart00707   3 LNRKLSQRPTREELEERNILKE 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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