|
Name |
Accession |
Description |
Interval |
E-value |
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
35-449 |
2.30e-130 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 381.79 E-value: 2.30e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 35 MSLkftnAKRIEGLDSNVWIEFTKL-----AADPSVVNLGQGFPDISPPTYVKEELskIAAI-DSLNQYTRGFGHPSLVK 108
Cdd:COG0436 1 MKL----SSRLARLPPSPIREVSALaaelkAAGEDVIDLGIGEPDFPTPDHIREAA--IEALdDGVTGYTPSAGIPELRE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 109 ALSYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPvygkrw 188
Cdd:COG0436 75 AIAAYYKRRYGVDLDPD-EILVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEEN------ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 189 sssDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGM 268
Cdd:COG0436 148 ---GFLPDPEALEAAITPRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPGL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 269 WERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrmDDPECYFNSLPKELEV 348
Cdd:COG0436 225 KDRTIVINSFSKSYAMTGWRIGYAVGPPELIAALLKLQSNLTSCAPTPAQYAAAAAL-------EGPQDYVEEMRAEYRR 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 349 KRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDlsdmknnepyDYKFVKWMTKHKKLSAIPVSAFCnsetkSQFEKFV 428
Cdd:COG0436 298 RRDLLVEGLNEIGLSVVKPEGAFYLFADVPELGLD----------SEEFAERLLEEAGVAVVPGSAFG-----PAGEGYV 362
|
410 420
....*....|....*....|.
gi 1159731393 429 RFCFIKKDSTLDAAEEIIKAW 449
Cdd:COG0436 363 RISYATSEERLEEALERLARF 383
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
44-449 |
1.36e-116 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 346.64 E-value: 1.36e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 44 RIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQID 123
Cdd:PRK07777 5 RLRPFGTTIFAEMSALAVRTGAVNLGQGFPDEDGPPEMLEAAQE-AIAGGVNQYPPGPGIPELRAAIAAQRRRRYGLEYD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 124 SNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwSSSDWTLDPQELESK 203
Cdd:PRK07777 84 PDTEVLVTVGATEAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLVP--------DGRGFALDLDALRAA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 204 FNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFS 283
Cdd:PRK07777 156 VTPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATLPGMRERTVTISSAAKTFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 284 VTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESVGLK 363
Cdd:PRK07777 236 VTGWKIGWACGPAPLIAAVRAAKQYLTYVGGAPFQPAVAHA-------LDHEDAWVAALRDSLQAKRDRLAAGLAEAGFE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 364 PIVPDGGYFIIADVSLLDPDLSdmknnepydYKFVKWMTKHKKLSAIPVSAFCNSEtkSQFEKFVRFCFIKKDSTLDAAE 443
Cdd:PRK07777 309 VHDSAGTYFLCADPRPLGYDDG---------TEFCRALPERVGVAAIPMSVFYDPA--DAWNHLVRFAFCKRDDTLDEAI 377
|
....*.
gi 1159731393 444 EIIKAW 449
Cdd:PRK07777 378 RRLRAL 383
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
59-449 |
2.54e-116 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 346.19 E-value: 2.54e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 59 LAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSL 138
Cdd:PRK08912 22 LAREHGAINLGQGFPDDPGPEDVRRAAAD-ALLDGSNQYPPMMGLPELRQAVAAHYARFQGLDLDPETEVMVTSGATEAL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 139 FNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrsKPvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHN 218
Cdd:PRK08912 101 AAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGVPRLVRL--EP--------PHWRLPRAALAAAFSPRTKAVLLNNPLN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 219 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHL 298
Cdd:PRK08912 171 PAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLMTLPGMRERTVKIGSAGKIFSLTGWKVGFVCAAPPL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 299 IKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESVGLkPIVPDGG-YFIIADV 377
Cdd:PRK08912 251 LRVLAKAHQFLTFTTPPNLQAAVAYG-------LGKPDDYFEGMRADLARSRDRLAAGLRRIGF-PVLPSQGtYFLTVDL 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1159731393 378 SLLDPDLSDMknnepydyKFVKWMTKHKKLSAIPVSAFcnsetksqFEK-----FVRFCFIKKDSTLDAAEEIIKAW 449
Cdd:PRK08912 323 APLGLAEDDV--------AFCRRLVEEAGVAAIPVSAF--------YEEdpvtsVVRFCFAKRDATLDEAVERLAAA 383
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
42-447 |
2.53e-106 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 321.43 E-value: 2.53e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 42 AKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEelSKIAAI-DSLNQYTRGFGHPSLVKALSYLYEKLYQK 120
Cdd:PLN00175 33 AKRLEKFKTTIFTQMSSLAIKHGAINLGQGFPNFDGPDFVKE--AAIQAIrDGKNQYARGFGVPELNSAIAERFKKDTGL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 121 QIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwsssDWTLDPQEL 200
Cdd:PLN00175 111 VVDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTLRPP----------DFAVPEDEL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 201 ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNkHLKIATFPGMWERTITIGSAGK 280
Cdd:PLN00175 181 KAAFTSKTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEGD-HISMASLPGMYERTVTMNSLGK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 281 TFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESV 360
Cdd:PLN00175 260 TFSLTGWKIGWAIAPPHLTWGVRQAHSFLTFATATPMQWAAVAA-------LRAPESYYEELKRDYSAKKDILVEGLKEV 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 361 GLKPIVPDGGYFIIADVSLLdpdlsDMKNnepyDYKFVKWMTKHKKLSAIPVSAF-CNSEtksQFEKFVRFCFIKKDSTL 439
Cdd:PLN00175 333 GFKVYPSSGTYFVMVDHTPF-----GFEN----DIAFCEYLIEEVGVAAIPPSVFyLNPE---DGKNLVRFAFCKDEETL 400
|
....*...
gi 1159731393 440 DAAEEIIK 447
Cdd:PLN00175 401 RAAVERMK 408
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
56-444 |
1.02e-102 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 311.08 E-value: 1.02e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 56 FT---KLAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTV 132
Cdd:PRK09082 20 FTvmsALAAEHGAINLSQGFPDFDGPPYLVEALAY-AMAAGHNQYPPMTGVAALREAIAAKTARLYGRQYDADSEITVTA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 133 GAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkPVYgkrwsSSDWtldpQELESKFNSKTKAII 212
Cdd:PRK09082 99 GATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQP-PDF-----RVDW----QRFAAAISPRTRLII 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 213 LNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWS 292
Cdd:PRK09082 169 LNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPELRERAFVVSSFGKTYHVTGWKVGYC 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 293 IGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrMDDPECYfNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYF 372
Cdd:PRK09082 249 VAPAALSAEFRKVHQYNTFTVNTPAQLALADYL------RAEPEHY-LELPAFYQAKRDRFRAALANSRFKLLPCEGTYF 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1159731393 373 IIADVSLLdPDLSDMknnepydyKFVKWMTKHKKLSAIPVSAFCNSetkSQFEKFVRFCFIKKDSTLDAAEE 444
Cdd:PRK09082 322 QLVDYSAI-SDLDDV--------EFCQWLTREHGVAAIPLSVFYAD---PFPHRLVRLCFAKQEETLDAAAE 381
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
66-448 |
6.18e-95 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 290.01 E-value: 6.18e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 66 VNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQAL 145
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPE-EIVVTNGAQEALSLLLRAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 146 IDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYN 225
Cdd:cd00609 80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEE---------GGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 226 REELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLkIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPN-HLIKHLQT 304
Cdd:cd00609 151 EEELEELAELAKKHGILIISDEAYAELVYDGEPPP-ALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPeELLERLKK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 305 VQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESVG-LKPIVPDGGYFIIADVSlldpd 383
Cdd:cd00609 230 LLPYTTSGPSTLSQAAAAAA-------LDDGEEHLEELRERYRRRRDALLEALKELGpLVVVKPSGGFFLWLDLP----- 297
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1159731393 384 lsdmknnEPYDYKFVKWMTKHKKLSAIPVSAFCnsetkSQFEKFVRFCFIKKDSTLDAAEEIIKA 448
Cdd:cd00609 298 -------EGDDEEFLERLLLEAGVVVRPGSAFG-----EGGEGFVRLSFATPEEELEEALERLAE 350
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
42-449 |
8.07e-88 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 273.15 E-value: 8.07e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 42 AKRIEGLDSNVWIEFTKLAA-------DpsVVNLGQGFPDISPPTYVKEelskiAAIDSLNQ----YTRGFGHPSLVKAL 110
Cdd:PRK05764 5 SKRVSRVTPSATLAVTAKAKelkaqgrD--VISLGAGEPDFDTPEHIKE-----AAIEALDDgktkYTPAAGIPELREAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 111 SYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsS 190
Cdd:PRK05764 78 AAKLKRDNGLDYDPS-QVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGE---------E 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 191 SDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF-PGMW 269
Cdd:PRK05764 148 NGFKLTVEQLEAAITPKTKALILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLsPELR 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 270 ERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTiYTCATplqeALAQafWIDIKRMDDPECYFNSLPKELEVK 349
Cdd:PRK05764 228 DRTITVNGFSKAYAMTGWRLGYAAGPKELIKAMSKLQSHS-TSNPT----SIAQ--YAAVAALNGPQDEVEEMRQAFEER 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 350 RDRMVRLLESV-GLKPIVPDGGYFIIADVSlldpdlSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSEtksqfekFV 428
Cdd:PRK05764 301 RDLMVDGLNEIpGLECPKPEGAFYVFPNVS------KLLGKSITDSLEFAEALLEEAGVAVVPGIAFGAPG-------YV 367
|
410 420
....*....|....*....|.
gi 1159731393 429 RFCFIKKDSTLDAAEEIIKAW 449
Cdd:PRK05764 368 RLSYATSLEDLEEGLERIERF 388
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
58-439 |
7.36e-71 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 229.29 E-value: 7.36e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 58 KLAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGS 137
Cdd:PRK12414 24 QLAAQHDALNLSQGAPNFAPDPALVEGVAR-AMRDGHNQYAPMAGIAALREALAEKTERLYGARYDPASEVTVIASASEG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 138 LFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrskpvygkrwSSSDWTLDPQELESKFNSKTKAIILNTPH 217
Cdd:PRK12414 103 LYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKL----------SPEDFRVNWDEVAAAITPRTRMIIVNTPH 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 218 NPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNH 297
Cdd:PRK12414 173 NPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRELAERSVIVSSFGKSYHVTGWRVGYCLAPAE 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 298 LIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFnSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADV 377
Cdd:PRK12414 253 LMDEIRKVHQFMVFSADTPMQHAFAEA-------LAEPASYL-GLGAFYQRKRDLLARELAGSRFELLPSEGSFFMLARF 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1159731393 378 SlldpDLSDMKNNEpydykFVKWMTKHKKLSAIPVSAFCNSETKSqfeKFVRFCFIKKDSTL 439
Cdd:PRK12414 325 R----HFSDESDSD-----FVLRLIRDARVATIPLSAFYTDGTDT---GLIRLSFSKDDATL 374
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
63-415 |
6.44e-60 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 200.72 E-value: 6.44e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 63 PSVVNLGQGFPDISPPTYVKEelSKIAAIDSlNQ--YTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFN 140
Cdd:PRK07309 30 PGILKLTLGEPDFTTPDHVKE--AAKRAIDA-NQshYTGMAGLLELRQAAADFVKEKYNLDYAPENEILVTIGATEALSA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 141 TIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwssSDWTLDPQELES---KFNSKTKAIILNTPH 217
Cdd:PRK07309 107 SLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTE----------NDFVLTPEMLEKailEQGDKLKAVILNYPA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 218 NPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpgMWERTITIGSAGKTFSVTGWKLGWSIGPNH 297
Cdd:PRK07309 177 NPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEY--LPDQTILINGLSKSHAMTGWRIGLIFAPAE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 298 LIKHLQTVQQNTIYTCATPLQEALAQAFwidIKRMDDPEcyfnSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADV 377
Cdd:PRK07309 255 FTAQLIKSHQYLVTAATTMAQFAAVEAL---TNGKDDAL----PMKKEYIKRRDYIIEKMTDLGFKIIKPDGAFYIFAKI 327
|
330 340 350
....*....|....*....|....*....|....*...
gi 1159731393 378 slldPDlsdmkNNEPYDYKFVKWMTKHKKLSAIPVSAF 415
Cdd:PRK07309 328 ----PA-----GYNQDSFKFLQDFARKKAVAFIPGAAF 356
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
55-432 |
3.61e-59 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 198.79 E-value: 3.61e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 55 EFTKLAAD-PSVVNLGQGFPDISPPTYVKEelSKIAAID-SLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTV 132
Cdd:PRK07683 19 QFSNMVQNyDNLISLTIGQPDFPTPSHVKE--AAKRAITeNYTSYTHNAGLLELRKAACNFVKDKYDLHYSPESEIIVTI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 133 GAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvygkrwsSSDWTLDPQELESKFNSKTKAII 212
Cdd:PRK07683 97 GASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTR----------STGFRLTAEALENAITEKTRCVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 213 LNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWS 292
Cdd:PRK07683 167 LPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ-PHTSIAHFPEMREKTIVINGLSKSHSMTGWRIGFL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 293 IGPNHLIKHLQTVQQNTIyTCATPLQ-----EALAQAFwidikrmDDPECYFNSLPKELEVKRDRMVrlleSVGLKPIVP 367
Cdd:PRK07683 246 FAPSYLAKHILKVHQYNV-TCASSISqyaalEALTAGK-------DDAKMMRHQYKKRRDYVYNRLI----SMGLDVEKP 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1159731393 368 DGGYFIIadvslldPDLSDMKNNEpydYKFVKWMTKHKKLSAIPVSAFcnsetkSQF-EKFVRFCF 432
Cdd:PRK07683 314 TGAFYLF-------PSIGHFTMSS---FDFALDLVEEAGLAVVPGSAF------SEYgEGYVRLSY 363
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
35-415 |
1.62e-56 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 191.47 E-value: 1.62e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 35 MSLKFTnAKRIEGLDSNVWIEFTKLAAD-PSVVNLGQGFPDIspPTyvKEELSKIAAIDSLNQYTR---GFGHPSLVKAL 110
Cdd:PRK06348 1 MKNKFL-AKKYQQMEVNIMAEIATLAKKfPDIIDLSLGDPDL--IT--DESIINAAFEDAKKGHTRytdSGGDVELIEEI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 111 SYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwss 190
Cdd:PRK06348 76 IKYYSKNYDLSFKRN-EIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEE--------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 191 SDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSgNKHLKIATFPGMWE 270
Cdd:PRK06348 146 DGFQINVKKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFY-EDFVPMATLAGMPE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 271 RTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikRMDDpecyfNSLPKELEVKR 350
Cdd:PRK06348 225 RTITFGSFSKDFAMTGWRIGYVIAPDYIIETAKIINEGICFSAPTISQRAAIYAL-----KHRD-----TIVPLIKEEFQ 294
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1159731393 351 DRMVRLLESVGLKP----IVPDGGYFIIADVSllDPDLSDMknnepydyKFVKWMTKHKKLSAIPVSAF 415
Cdd:PRK06348 295 KRLEYAYKRIESIPnlslHPPKGSIYAFINIK--KTGLSSV--------EFCEKLLKEAHVLVIPGKAF 353
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
56-372 |
6.79e-54 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 184.55 E-value: 6.79e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 56 FTKLAAD-PSVVNLGQGFPDISPPTYVKEelskiAAIDSLNQ----YTRGFGHPSLVKALS-YLYEKlYQKQIDSNKEIL 129
Cdd:PRK07682 12 FFDLAANmEGVISLGVGEPDFVTPWNVRE-----ASIRSLEQgytsYTANAGLLELRQEIAkYLKKR-FAVSYDPNDEII 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 130 VTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTK 209
Cdd:PRK07682 86 VTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVATTLE---------NEFKVQPAQIEAAITAKTK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 210 AIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMWERTITIGSAGKTFSVTGWKL 289
Cdd:PRK07682 157 AILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE-AYTSFASIKGMRERTILISGFSKGFAMTGWRL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 290 GWSIGPNHLIKHLQTVQQNTIYTCATPLQ----EALAQAfwidikrMDDPECYFNSLPKelevKRDRMVRLLESVGLKPI 365
Cdd:PRK07682 236 GFIAAPVYFSEAMLKIHQYSMMCAPTMAQfaalEALRAG-------NDDVIRMRDSYRK----RRNFFVTSFNEIGLTCH 304
|
....*..
gi 1159731393 366 VPDGGYF 372
Cdd:PRK07682 305 VPGGAFY 311
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
65-432 |
1.95e-53 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 182.50 E-value: 1.95e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 65 VVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQA 144
Cdd:pfam00155 3 KINLGSNEYLGDTLPAVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAVVFGSGAGANIEALIFL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 145 LIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrskpvygkrWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVY 224
Cdd:pfam00155 83 LANPGDAILVPAPTYASYIRIARLAGGEVVRYPL---------YDSNDFHLDFDALEAALKEKPKVVLHTSPHNPTGTVA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 225 NREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF--PGMWerTITIGSAGKTFSVTGWKLGWSIGPNHLIKHL 302
Cdd:pfam00155 154 TLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALlaEGPN--LLVVGSFSKAFGLAGWRVGYILGNAAVISQL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 303 QTVQQNTIYTcaTPLQEALAQAfwidikrMDDPE---CYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFiiadvSL 379
Cdd:pfam00155 232 RKLARPFYSS--THLQAAAAAA-------LSDPLlvaSELEEMRQRIKERRDYLRDGLQAAGLSVLPSQAGFF-----LL 297
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1159731393 380 LDPDLSDMKnnepydyKFVKWMTKHKKLSAIPVSAFCNSEtksqfekFVRFCF 432
Cdd:pfam00155 298 TGLDPETAK-------ELAQVLLEEVGVYVTPGSSPGVPG-------WLRITV 336
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
56-450 |
5.28e-51 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 177.38 E-value: 5.28e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 56 FTKLAADPSVVNLGQGFPDISPPTYVKEElSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAY 135
Cdd:PRK08361 26 FERASKMENVISLGIGEPDFDTPKNIKEA-AKRALDEGWTHYTPNAGIPELREAIAEYYKKFYGVDVDVD-NVIVTAGAY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 136 GSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNT 215
Cdd:PRK08361 104 EATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREE---------NEFQPDPDELLELITKRTRMIVINY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 216 PHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGmwERTITIGSAGKTFSVTGWKLGWSIGP 295
Cdd:PRK08361 175 PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKYAP--DNTILANSFSKTFAMTGWRLGFVIAP 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 296 NHLIKHLQTVQQNTIYTCATPLQ----EAL-AQAFWIDIKRMddpecyfnslpKELEVKRDRMV--RLLESVGLKPIVPD 368
Cdd:PRK08361 253 EQVIKDMIKLHAYIIGNVASFVQiagiEALrSKESWKAVEEM-----------RKEYNERRKLVlkRLKEMPHIKVFEPK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 369 GGYFIIADVSLLdpdlsDMKNNEpydykFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRFCF-IKKDSTLDAAEEIIK 447
Cdd:PRK08361 322 GAFYVFANIDET-----GMSSED-----FAEWLLEKARVVVIPGTAF-----GKAGEGYIRISYaTSKEKLIEAMERMEK 386
|
...
gi 1159731393 448 AWS 450
Cdd:PRK08361 387 ALE 389
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
67-448 |
1.87e-46 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 165.41 E-value: 1.87e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 67 NLGQgfPDISPPTYVKEELSKIAaiDSLNQYTRGFGHPSLVKALSYLYEKLyqkQIDSNKE-ILVTVGAYGSLFNTIQAL 145
Cdd:PRK07568 36 NIGQ--PDIKTPEVFFEAIKNYD--EEVLAYSHSQGIPELREAFAKYYKKW---GIDVEPDeILITNGGSEAILFAMMAI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 146 IDEGDEVILIVPFYDCYEPMVRMAGATPVfiPLRSKPVYGKRWSSsdwtldPQELESKFNSKTKAIILNTPHNPLGKVYN 225
Cdd:PRK07568 109 CDPGDEILVPEPFYANYNGFATSAGVKIV--PVTTKIEEGFHLPS------KEEIEKLITPKTKAILISNPGNPTGVVYT 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 226 REELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPN-HLIKHLQT 304
Cdd:PRK07568 181 KEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSALSLEGLEDRVIIIDSVSKRYSACGARIGCLISKNkELIAAAMK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 305 VQQNTIyTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESV-GLKPIVPDGGYFIIADVSLLDPD 383
Cdd:PRK07568 261 LCQARL-SPPTLEQIGAAAL-------LDTPESYFDEVREEYKKRRDILYEELNKIpGVVCEKPKGAFYIIAKLPVDDAE 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 384 lsdmknnepydyKFVKWMTKH-----KKLSAIPVSAFCNSETKSQFEkfVRFCFIKKDSTLDAAEEIIKA 448
Cdd:PRK07568 333 ------------DFAKWLLTDfnyngETVMVAPASGFYATPGLGKNE--IRIAYVLNEEDLKRAMEILKE 388
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
60-373 |
9.60e-44 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 158.36 E-value: 9.60e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 60 AADPSVVNLGQGFPDISPPTYVKEelSKIAAIDS-LNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAYGSL 138
Cdd:PRK06107 30 AAGRSIVDLTVGEPDFDTPDHIKQ--AAVAAIERgETKYTLVNGTPALRKAIIAKLERRNGLHYADN-EITVGGGAKQAI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 139 FNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHN 218
Cdd:PRK06107 107 FLALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPE---------EQGFKLTPEALEAAITPRTRWLILNAPSN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 219 PLGKVYNREELQVIADLCIKY-DTLCISDEVYEWLVYSG--NKHLkIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGP 295
Cdd:PRK06107 178 PTGAVYSRAELRALADVLLRHpHVLVLTDDIYDHIRFDDepTPHL-LAAAPELRDRVLVTNGVSKTYAMTGWRIGYAAGP 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1159731393 296 NHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDikrmddpECYFNSLPKELEVKRDRMVRLLESV-GLKPIVPDGGYFI 373
Cdd:PRK06107 257 ADLIAAINKLQSQSSSCPSSISQAAAAAALNGD-------QSFVTESVAVYKQRRDYALALLNAIpGLSCLVPDGAFYL 328
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
59-313 |
3.65e-43 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 156.39 E-value: 3.65e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 59 LAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSylyEKLYQK---QIDSNKEILVTVGAY 135
Cdd:PRK05957 23 IRENPGTISLGQGVVSYPPPPEAIEALNNFLANPENHKYQAVQGIPPLLEAIT---QKLQQDngiELNNEQAIVVTAGSN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 136 GSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPlrskpvygkrwSSSDWTLDPQELESKFNSKTKAIILNT 215
Cdd:PRK05957 100 MAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPILVP-----------TDDNYQLQPEAIEQAITPKTRAIVTIS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 216 PHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGP 295
Cdd:PRK05957 169 PNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHFSPGSIPGSGNHTISLYSLSKAYGFASWRIGYMVIP 248
|
250
....*....|....*...
gi 1159731393 296 NHLIKHLQTVqQNTIYTC 313
Cdd:PRK05957 249 IHLLEAIKKI-QDTILIC 265
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
59-449 |
1.02e-42 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 154.72 E-value: 1.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 59 LAADPS----VVNLGQGFPDISP----------PTYVKEelskiAAIDSLNQ----YTRGFGHPSLVKALSYLYEKLYQK 120
Cdd:PRK06108 6 RALPESgireVANAGRGREGVLPlwfgesdlptPDFIRD-----AAAAALADgetfYTHNLGIPELREALARYVSRLHGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 121 QIDSnKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvYGkrwsSSDWTLDPQEL 200
Cdd:PRK06108 81 ATPP-ERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLD----FG----GGGWTLDLDRL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 201 ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGN----KHLKIATfPGmwERTITIG 276
Cdd:PRK06108 152 LAAITPRTRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGgrapSFLDIAE-PD--DRIIFVN 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 277 SAGKTFSVTGWKLGWSIGPNHLIKHL-QTVQQNTiyTC-ATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMV 354
Cdd:PRK06108 229 SFSKNWAMTGWRLGWLVAPPALGQVLeKLIEYNT--SCvAQFVQRAAVAA-------LDEGEDFVAELVARLRRSRDHLV 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 355 RLLESV-GLKPIVPDGGYFIIADVslldPDLSDMKnnepydyKFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRFCFI 433
Cdd:PRK06108 300 DALRALpGVEVAKPDGAMYAFFRI----PGVTDSL-------ALAKRLVDEAGLGLAPGTAF-----GPGGEGFLRWCFA 363
|
410
....*....|....*.
gi 1159731393 434 KKDSTLDAAEEIIKAW 449
Cdd:PRK06108 364 RDPARLDEAVERLRRF 379
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
60-432 |
9.67e-39 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 144.43 E-value: 9.67e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 60 AADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKeILVTVGAYGSLF 139
Cdd:PRK07337 27 RAGRDIIHMGIGEPDFTAPEPVVEAAAR-ALRRGVTQYTSALGLAPLREAIAAWYARRFGLDVAPER-IVVTAGASAALL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 140 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPlrSKPVygKRWSssdwtLDPQELESKFNSKTKAIILNTPHNP 219
Cdd:PRK07337 105 LACLALVERGDEVLMPDPSYPCNRHFVAAAEGRPVLVP--SGPA--ERFQ-----LTAADVEAAWGERTRGVLLASPSNP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 220 LGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIAtfpgMWERTITIGSAGKTFSVTGWKLGWSIGPNHLI 299
Cdd:PRK07337 176 TGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALS----LGDDVITINSFSKYFNMTGWRLGWLVVPEALV 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 300 KHLQTVQQNtIYTCATPL-QEALAQAFwidikrmdDPECY--FNSLPKELEVKRDRMVRLLESVGLK-PIVPDGGYFIIA 375
Cdd:PRK07337 252 GTFEKLAQN-LFICASALaQHAALACF--------EPDTLaiYERRRAEFKRRRDFIVPALESLGFKvPVMPDGAFYVYA 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1159731393 376 DVS-LLDPDLSDmknnepyDYKFVKWMTKHKKLSAIPVSAFCNSETksqfEKFVRFCF 432
Cdd:PRK07337 323 DCRgVAHPAAGD-------SAALTQAMLHDAGVVLVPGRDFGPHAP----RDYIRLSY 369
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
37-448 |
2.64e-38 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 143.41 E-value: 2.64e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 37 LKFTNAKRIEGLDSNVWIEFT-----KLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGfGHPSLVKALS 111
Cdd:PRK07681 1 MTYTLATRMKAFQSSIFSELGaykkeKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLS-GIQEFHEAVT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 112 YLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssS 191
Cdd:PRK07681 80 EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKE---------N 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 192 DWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWER 271
Cdd:PRK07681 151 DFLPDLELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 272 TITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikRMDDPECYFNslpKEL-EVKR 350
Cdd:PRK07681 231 GVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKSNTDYGVFLPIQKAACAAL-----RNGAAFCEKN---RGIyQERR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 351 DRMVRLLESVGLKPIVPDGGYFIIADVslldPDLSDmknnepyDYKFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRF 430
Cdd:PRK07681 303 DTLVDGFRTFGWNVDKPAGSMFVWAEI----PKGWT-------SLSFAYALMDRANVVVTPGHAF-----GPHGEGFVRI 366
|
410
....*....|....*...
gi 1159731393 431 CFIKKDSTLDAAEEIIKA 448
Cdd:PRK07681 367 ALVQDEEVLQQAVENIRN 384
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
65-373 |
4.21e-36 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 137.25 E-value: 4.21e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 65 VVNLGQGFP---DISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSnKEILVTVGAYGSLFNT 141
Cdd:PRK08363 32 VIRLNIGDPvkfDFQPPEHMKEAYCR-AIKEGHNYYGPSEGLPELREAIVKREKRKNGVDITP-DDVRVTAAVTEALQLI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 142 IQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIplrskpvygKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLG 221
Cdd:PRK08363 110 FGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVEY---------RTIEEEGWQPDIDDIRKKITEKTKAIAVINPNNPTG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 222 KVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMwERTITIGSAGKTFSVTGWKLGWS--IGPNhli 299
Cdd:PRK08363 181 ALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEG-KHVSPGSLTKD-VPVIVMNGLSKVYFATGWRLGYIyfVDPE--- 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 300 KHLQTVQQNT-----IYTCA-TPLQEALAQAFwidIKRMDdpecYFNSLPKELEVKRDRMV-RLLESVGLKPIVPDGGYF 372
Cdd:PRK08363 256 GKLAEVREAIdklarIRLCPnTPAQFAAIAGL---TGPMD----YLEEYMKKLKERRDYIYkRLNEIPGISTTKPQGAFY 328
|
.
gi 1159731393 373 I 373
Cdd:PRK08363 329 I 329
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
97-296 |
1.25e-35 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 135.60 E-value: 1.25e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 97 YTrgFGHPSLVKALSYLYEKLYQKQIDsnKE-ILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVF 175
Cdd:COG1168 62 YT--APPDEYYEAIIDWLKRRHGWEID--PEwIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVE 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 176 IPLRskpvygkrWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYS 255
Cdd:COG1168 138 NPLI--------LEDGRYRIDFDDLEAKLDPGVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLP 209
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1159731393 256 GNKHLKIATF-PGMWERTITIGSAGKTFSVTGWKLGWSIGPN 296
Cdd:COG1168 210 GHKHTPFASLsEEAADRTITLTSPSKTFNLAGLKASYAIIPN 251
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
71-415 |
2.60e-35 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 134.94 E-value: 2.60e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 71 GFPDISPPTYVKEELSKIA--AIDSLNQYTRGFGHPSLVKALSylyEKLYQKQ-IDSNKE-ILVTVGAYGSLFNTIQALI 146
Cdd:PRK06836 41 GNPSVPPPAAVKEALRELAeeEDPGLHGYMPNAGYPEVREAIA---ESLNRRFgTPLTADhIVMTCGAAGALNVALKAIL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 147 DEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwsssDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNR 226
Cdd:PRK06836 118 NPGDEVIVFAPYFVEYRFYVDNHGGKLVVVPTDTD----------TFQPDLDALEAAITPKTKAVIINSPNNPTGVVYSE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 227 EELQVIADL----CIKYDT--LCISDEVYEWLVYSGnkhLKIATFPGMWERTITIGSAGKTFSVTGWKLGWsIGPNHLIK 300
Cdd:PRK06836 188 ETLKALAALleekSKEYGRpiYLISDEPYREIVYDG---AEVPYIFKYYDNSIVVYSFSKSLSLPGERIGY-IAVNPEME 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 301 HLQT-----VQQNTI--YTCATPL-QEALAQAfwIDIKRmdDPECYfnslpkelEVKRDRMVRLLESVGLKPIVPDGGYF 372
Cdd:PRK06836 264 DADDlvaalVFANRIlgFVNAPALmQRVVAKC--LDATV--DVSIY--------KRNRDLLYDGLTELGFECVKPQGAFY 331
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1159731393 373 IIadVSLLDPDlsdmknnepyDYKFVKWMTKHKKLsAIPVSAF 415
Cdd:PRK06836 332 LF--PKSPEED----------DVAFCEKAKKHNLL-LVPGSGF 361
|
|
| C_S_lyase_PatB |
TIGR04350 |
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ... |
101-385 |
4.97e-34 |
|
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).
Pssm-ID: 275146 Cd Length: 384 Bit Score: 131.29 E-value: 4.97e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 101 FGHP----SLVKALSYLYEKLYQKQIDsNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFI 176
Cdd:TIGR04350 56 FGYTlppdSLYAAVINWLAQRHGWQID-PEDIVFLPGVVPSLFAAVRALTAPGEGVIVQTPVYPPFLSAVKSNGRELVLN 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 177 PLRskpvygkrWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSG 256
Cdd:TIGR04350 135 PLK--------LDEGRYRFDLEDLEDAITEKARLLLLCSPHNPVGRVWTREELTRLAELCLRHNVVVVSDEIHADLVYPP 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 257 NKHLKIAT-FPGMWERTITIGSAGKTFSVTGWKLGWSIGPNH-LIKHLQTVQQNTIYTCATPLQEALAQAFWidikrmDD 334
Cdd:TIGR04350 207 NKHIPLASlSPEPAERTVTLLSPGKTFNIAGLNISFAIIPNPeLRRAFQEAAQRVHIQHGNLFGYVAFEAAY------RD 280
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1159731393 335 PECYFNSLPKELEVKRDRMVRLL--ESVGLKPIVPDGGYFIIADVSLL---DPDLS 385
Cdd:TIGR04350 281 GEPWLDALLAYLRGNRDLVEEFIakRLPQIRVRPPEATYLAWLDCRALgldDADLR 336
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
60-383 |
1.15e-33 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 130.17 E-value: 1.15e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 60 AADPSVVNLGQGFPDISPPTYVKEelSKIAAIDSLN-QYTRGFGHPSLVKALSYLYEKLYQKQIDSNKeILVTVGAYGSL 138
Cdd:PRK08960 29 AAGHDVIHLEIGEPDFTTAEPIVA--AGQAALAAGHtRYTAARGLPALREAIAGFYAQRYGVDVDPER-ILVTPGGSGAL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 139 FNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHN 218
Cdd:PRK08960 106 LLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGP---------DSRYQLTPALVERHWNADTVGALVASPAN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 219 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSgnkhLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHL 298
Cdd:PRK08960 177 PTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYG----VDAASVLEVDDDAFVLNSFSKYFGMTGWRLGWLVAPPAA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 299 IKHLQTVQQNTIYTCATPLQEALAQAFwidikrmdDPECY--FNSLPKELEVKRDRMVRLLESVGLK-PIVPDGGYFIIA 375
Cdd:PRK08960 253 VPELEKLAQNLYISASTPAQHAALACF--------EPETLaiLEARRAEFARRRDFLLPALRELGFGiAVEPQGAFYLYA 324
|
....*...
gi 1159731393 376 DVSLLDPD 383
Cdd:PRK08960 325 DISAFGGD 332
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
59-432 |
1.13e-31 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 126.10 E-value: 1.13e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 59 LAADPSVVNLGQGFPDIS--PPTYVKEELSKIAAID--SLNQYTRGFGHPSLVKALSylyEKLYQKQID-SNKEILVTVG 133
Cdd:COG1167 102 LEAAPGVIDLGSGAPDPDlfPLAALRRALRRALRRLppALLGYGDPQGLPELREAIA---RYLARRGVPaSPDQILITSG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 134 AYGSLFNTIQALIDEGDEVILIVPfydCYEPMV---RMAGATPVFIPLRSkpvYGkrwsssdwtLDPQELESKF-NSKTK 209
Cdd:COG1167 179 AQQALDLALRALLRPGDTVAVESP---TYPGALaalRAAGLRLVPVPVDE---DG---------LDLDALEAALrRHRPR 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 210 AIILnTP--HNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMwERTITIGSAGKTFSvTGW 287
Cdd:COG1167 244 AVYV-TPshQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAP-GRVIYIGSFSKTLA-PGL 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 288 KLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQafWID-------IKRMddpecyfnslPKELEVKRDRMVRLLESV 360
Cdd:COG1167 321 RLGYLVAPGRLIERLARLKRATDLGTSPLTQLALAE--FLEsghydrhLRRL----------RREYRARRDLLLAALARH 388
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1159731393 361 ---GLKPIVPDGGYFIIADvslLDPDLSDMknnepydyKFVKWMTKHkKLSAIPVSAFCNSEtksQFEKFVRFCF 432
Cdd:COG1167 389 lpdGLRVTGPPGGLHLWLE---LPEGVDAE--------ALAAAALAR-GILVAPGSAFSADG---PPRNGLRLGF 448
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
56-448 |
4.95e-30 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 120.52 E-value: 4.95e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 56 FTKLAADPSVVNLGQGFPDISP--PTYVKEELSKIAAIDS--LNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVT 131
Cdd:TIGR01265 24 KVKPNPEKPVIPLSHGDPSVFGnlRTDPEAEEAVKDALRSgkFNGYAPSVGALAAREAVAEYLSSDLPGKLTAD-DVVLT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 132 VGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGatpvfIPLRskpvYGKRWSSSDWTLDPQELESKFNSKTKAI 211
Cdd:TIGR01265 103 SGCSQAIEICIEALANPGANILVPRPGFPLYDTRAAFSG-----LEVR----LYDLLPEKDWEIDLDGLESLADEKTVAI 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 212 ILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERtITIGSAGKTFSVTGWKLGW 291
Cdd:TIGR01265 174 VVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASIVPV-LSLGGISKRWVVPGWRLGW 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 292 SI--GPNHLIKH--LQTVQQNTIYTC--ATPLQEALAqafwiDIKRmDDPECYFNSLPKELevKRDRMV---RLLESVGL 362
Cdd:TIGR01265 253 IIihDPHGIFRDtvLQGLKNLLQRILgpATIVQGALP-----DILE-NTPQEFFDGKISVL--KSNAELcyeELKDIPGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 363 KPIVPDGGYFIIADVSL-LDPDLSDmknnepyDYKFVKWMTKHKKLSAIPVSAFcnsetksQFEKFVRFCFIKKDSTLDA 441
Cdd:TIGR01265 325 VCPKPEGAMYLMVKLELeLFPEIKD-------DVDFCEKLAREESVICLPGSAF-------GLPNWVRITITVPESMLEE 390
|
....*..
gi 1159731393 442 AEEIIKA 448
Cdd:TIGR01265 391 ACSRIKE 397
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
38-377 |
1.77e-29 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 118.48 E-value: 1.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 38 KFTNAKRIEGLDSNVWIEFTKLAADP-----SVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSY 112
Cdd:PRK09276 1 MMKLADRIKNLPPYLFAEIDKKKAEKiargvDVISLGIGDPDLPTPDHIIEAMCKAVEDPENHQYPSYEGMLEFRKAVAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 113 LYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRS----KPvygkrw 188
Cdd:PRK09276 81 WYKRRFGVELDPETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLKEengfLP------ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 189 sssDWTLDPQELESKfnskTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGM 268
Cdd:PRK09276 155 ---DLDAIPEDVAKK----AKLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEVPGA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 269 WERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEAlaqafwiDIKRMDDPECYFNSLPKELEV 348
Cdd:PRK09276 228 KDVGIEFHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKSNVDSGVFQAIQEA-------GIAALNGPQEVVEELRKIYQE 300
|
330 340
....*....|....*....|....*....
gi 1159731393 349 KRDRMVRLLESVGLKPIVPDGGYFIIADV 377
Cdd:PRK09276 301 RRDILVEGLRKLGLEVEPPKATFYVWAPV 329
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
77-388 |
1.97e-28 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 116.04 E-value: 1.97e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 77 PPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQkQIDSNKE------ILVTVGAYGSLFNTIQALIDEGD 150
Cdd:PTZ00433 51 TPAIQTKALVEAVDSQECNGYPPTVGSPEAREAVATYWRNSFV-HKESLKStikkdnVVLCSGVSHAILMALTALCDEGD 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 151 EVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQ 230
Cdd:PTZ00433 130 NILVPAPGFPHYETVCKAYGIEMRFYNCRP---------EKDWEADLDEIRRLVDDRTKALIMTNPSNPCGSNFSRKHVE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 231 VIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAgKTFSVTGWKLGWSI-------GPNhLIKHLQ 303
Cdd:PTZ00433 201 DIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPRVILGGTA-KNLVVPGWRLGWLLlvdphgnGGD-FLDGMK 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 304 TVQQNTIYTCATpLQEALAQAFwidikrMDDPECYFNSLPKELEVKRDRMVRLLES-VGLKPIVPDGGYFIIA--DVSLL 380
Cdd:PTZ00433 279 RLGMLVCGPCSV-VQAALGEAL------LNTPQEHLEQIVAKLEEGAMVLYNHIGEcIGLSPTMPRGSMFLMSrlDLEKF 351
|
....*...
gi 1159731393 381 DPDLSDMK 388
Cdd:PTZ00433 352 RDIKSDVE 359
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
62-415 |
1.07e-27 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 113.72 E-value: 1.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 62 DPSVvnlgqgFPDISPPTYVKEELSKiaAIDS--LNQYTRGFGHPSLVKALSYLYEKLyQKQIDSNkEILVTVGAYGSLF 139
Cdd:TIGR01264 40 DPTV------FGNLPTDPEVMQAMKD--SLDSgkYNGYAPTVGALSAREAIASYYHNP-DGPIEAD-DVVLCSGCSHAIE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 140 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGatpvfipLRSKPvYGKRwSSSDWTLDPQELESKFNSKTKAIILNTPHNP 219
Cdd:TIGR01264 110 MCIAALANAGQNILVPRPGFPLYETLAESMG-------IEVKL-YNLL-PDKSWEIDLKQLESLIDEKTAALIVNNPSNP 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 220 LGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERtITIGSAGKTFSVTGWKLGWSIGPNH-- 297
Cdd:TIGR01264 181 CGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVPI-LSCGGLAKRWLVPGWRLGWIIIHDRrg 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 298 ----LIKHLQTVQQNTIYTCaTPLQEALAQAFwidikrMDDPECYFNSLPKELEVKRDRMVRLL-ESVGLKPIVPDGGYF 372
Cdd:TIGR01264 260 ilrdIRDGLVKLSQRILGPC-TIVQGALPSIL------LRTPQEYFDGTLSVLESNAMLCYGALaAVPGLRPVMPSGAMY 332
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1159731393 373 IIADVSLldPDLSDMKNnepyDYKFVKWMTKHKKLSAIPVSAF 415
Cdd:TIGR01264 333 MMVGIEM--EHFPEFKN----DVEFTERLVAEQSVFCLPGSCF 369
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
60-372 |
5.17e-26 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 108.89 E-value: 5.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 60 AADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSnKEILVTVGAYGSLF 139
Cdd:PRK07550 26 GADGPLIDLSQAVPGYPPPPELLRALAEAAADPAAHLYGPVEGLPELREAYAAHYSRLYGAAISP-EQVHITSGCNQAFW 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 140 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPvygkrwsssDWTLDPQELESKFNSKTKAIILNTPHNP 219
Cdd:PRK07550 105 AAMVTLAGAGDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEGP---------GLLPDPAAAEALITPRTRAIALVTPNNP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 220 LGKVYNREELQVIADLCIKYDTLCISDEVY-EWLVYSGNKHLKIATfPGmWERT-ITIGSAGKTFSVTGWKLGWSIGPNH 297
Cdd:PRK07550 176 TGVVYPPELLHELYDLARRHGIALILDETYrDFDSGGGAPHDLFAD-PD-WDDTlVHLYSFSKSYALTGHRVGAVVASPA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 298 LIKHLQTVqQNTIYTCATPL-QEALAQAF-----WIDIKRMddpecyfnslpkELEVKRDRMVRLLESVGLKPIVPDGGY 371
Cdd:PRK07550 254 RIAEIEKF-MDTVAICAPRIgQIAVAWGLpnladWRAGNRA------------EIARRRDAFRAVFARLPGWELLASGAY 320
|
.
gi 1159731393 372 F 372
Cdd:PRK07550 321 F 321
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
57-372 |
5.89e-26 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 108.86 E-value: 5.89e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 57 TKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYG 136
Cdd:PRK08068 26 KKVAEGHDVINLGQGNPDQPTPEHIVEALQEAAENPANHKYSPFRGYPFLKEAAADFYKREYGVTLDPETEVAILFGGKA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 137 SLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNTP 216
Cdd:PRK08068 106 GLVELPQCLMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIAE---------NNFLPDYTKIPEEVAEKAKLMYLNYP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 217 HNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPN 296
Cdd:PRK08068 177 NNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKPVSFLQTPGAKDVGIELYTLSKTFNMAGWRVAFAVGNE 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1159731393 297 HLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrMDDPECyFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYF 372
Cdd:PRK08068 257 SVIEAINLLQDHLFVSLFGAIQDAAIEAL------LSDQSC-VAELVARYESRRNAFISACREIGWEVDAPKGSFF 325
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
102-322 |
1.45e-24 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 104.63 E-value: 1.45e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 102 GHPSLVKALSylyeKLYQKQIDSNkeILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSK 181
Cdd:PRK07324 63 GSPEFKEAVA----SLYQNVKPEN--ILQTNGATGANFLVLYALVEPGDHVISVYPTYQQLYDIPESLGAEVDYWQLKEE 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 182 pvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNkhlk 261
Cdd:PRK07324 137 ---------NGWLPDLDELRRLVRPNTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDGS---- 203
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1159731393 262 IATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQ-NTIytCATPLQEALA 322
Cdd:PRK07324 204 TPSIADLYEKGISTNSMSKTYSLPGIRVGWIAANEEVIDILRKYRDyTMI--CAGVFDDMLA 263
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
122-386 |
6.25e-24 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 103.31 E-value: 6.25e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 122 IDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVygkrwsSSDWTLDPQELE 201
Cdd:PRK06207 99 VDAADELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDYLSA------DKRAGLDLDQLE 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 202 SKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKT 281
Cdd:PRK06207 173 EAFKAGVRVFLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRALPIDPENVITIMGPSKT 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 282 FSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrmDDPECYFNSLPKELEVKRDRMVRLLESV- 360
Cdd:PRK06207 253 ESLSGYRLGVAFGSPAIIDRMEKLQAIVSLRAAGYSQAVLRTWF-------SEPDGWMKDRIARHQAIRDDLLRVLRGVe 325
|
250 260
....*....|....*....|....*.
gi 1159731393 361 GLKPIVPDGGYFIIADVSLLDPDLSD 386
Cdd:PRK06207 326 GVFVRAPQAGSYLFPRLPRLAVSLHD 351
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
77-377 |
3.34e-23 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 99.82 E-value: 3.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 77 PPTYVKEELSkiAAIDSLNQYTRGfGHPSLVKALS-YLyeklyqkQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILI 155
Cdd:COG0079 27 PPPKVLEAIA--AALDALNRYPDP-DATALREALAeYY-------GVPPE-QVLVGNGSDELIQLLARAFLGPGDEVLVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 156 VPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsssDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADL 235
Cdd:COG0079 96 EPTFSEYPIAARAAGAEVVEVPLDE-----------DFSLDLDALLAAITERTDLVFLCNPNNPTGTLLPREELEALLEA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 236 CiKYDTLCISDEVY-EwlvYSGNKH----LkIATFPGMwertITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQntI 310
Cdd:COG0079 165 L-PADGLVVVDEAYaE---FVPEEDsalpL-LARYPNL----VVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRG--P 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1159731393 311 YTCATPLQEALAQAfwidikrMDDPEcYFNSLPKELEVKRDRMVRLLESVGLKPiVPDGGYFIIADV 377
Cdd:COG0079 234 WNVNSLAQAAALAA-------LEDRA-YLEETRARLRAERERLAAALRALGLTV-YPSQANFVLVRV 291
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
60-324 |
3.75e-23 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 100.91 E-value: 3.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 60 AADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLF 139
Cdd:PRK09148 27 AAGADIIDLGMGNPDLPTPQHIVDKLCETAQDPRTHRYSASKGIPGLRRAQAAYYARRFGVKLNPDTQVVATLGSKEGFA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 140 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYgkrwsssdwtLDPQELESKFN-SKTKAIILNTPHN 218
Cdd:PRK09148 107 NMAQAITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVPAEPDEEF----------FPALERAVRHSiPKPIALIVNYPSN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 219 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHL 298
Cdd:PRK09148 177 PTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPSVLQVPGAKDVTVEFTSMSKTFSMAGWRMGFAVGNERL 256
|
250 260
....*....|....*....|....*.
gi 1159731393 299 IKHLQTVQQNTIYTCATPLQEALAQA 324
Cdd:PRK09148 257 IAALTRVKSYLDYGAFTPIQVAATAA 282
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
65-448 |
4.51e-23 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 100.56 E-value: 4.51e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 65 VVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQA 144
Cdd:PRK08175 31 IIDFSMGNPDGPTPPHIVEKLCEVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVDIDPESEAIVTIGSKEGLAHLMLA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 145 LIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrskpVYGKRWSSsdwtldpqELESKFNS---KTKAIILNTPHNPLG 221
Cdd:PRK08175 111 TLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPL----VEGVDFFN--------ELERAIREsypKPKMMILGFPSNPTA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 222 KVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKH 301
Cdd:PRK08175 179 QCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDVAVEFFTLSKSYNMAGWRIGFMVGNPELVSA 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 302 LQTVQQNTIYTCATPLQEAlaqafwiDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSlld 381
Cdd:PRK08175 259 LARIKSYHDYGTFTPLQVA-------AIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIP--- 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1159731393 382 pdlsdmknnEPY----DYKFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRFCFIKKDSTLDAAEEIIKA 448
Cdd:PRK08175 329 ---------EPYaamgSLEFAKKLLNEAKVCVSPGIGF-----GDYGDTHVRFALIENRDRIRQAIRGIKA 385
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
141-300 |
6.40e-23 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 100.27 E-value: 6.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 141 TIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFipLRSKPvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHNPL 220
Cdd:PRK09265 111 AMQALLNNGDEVLVPAPDYPLWTAAVSLSGGKPVH--YLCDE-------EAGWFPDLDDIRSKITPRTKAIVIINPNNPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 221 GKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF-PGMWerTITIGSAGKTFSVTGWKLGWSI--GPNH 297
Cdd:PRK09265 182 GAVYSKELLEEIVEIARQHNLIIFADEIYDKILYDGAVHISIASLaPDLL--CVTFNGLSKAYRVAGFRVGWMVlsGPKK 259
|
...
gi 1159731393 298 LIK 300
Cdd:PRK09265 260 HAK 262
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
141-293 |
8.98e-23 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 100.97 E-value: 8.98e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 141 TIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPL 220
Cdd:PRK13355 224 SMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHYRCDEQ---------SEWYPDIDDIRSKITSRTKAIVIINPNNPT 294
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1159731393 221 GKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF-PGMWerTITIGSAGKTFSVTGWKLGWSI 293
Cdd:PRK13355 295 GALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMDGLEHTSIASLaPDLF--CVTFSGLSKSHMIAGYRIGWMI 366
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
35-361 |
1.07e-22 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 99.41 E-value: 1.07e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 35 MSLKFTN-AKRIEGLDSNVWIEFTKLAADP-----SVVNLGQGFPDISPPTYVKEelskiAAIDSL-NQYTRGF----GH 103
Cdd:PRK05942 1 MSLDWITpADRLQALPPYVFARLDELKARAreqglDLIDLGMGNPDGAAPQPVIE-----AAIAALaDPQNHGYppfeGT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 104 PSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCY--EPMVrmAGATPVFIPLRSK 181
Cdd:PRK05942 76 ASFRQAITDWYHRRYGVELDPDSEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAYPAHfrGPLI--AGAQIYPIILKPE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 182 pvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLK 261
Cdd:PRK05942 154 ---------NDWLIDLSSIPEEVAQQAKILYFNYPSNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGYQPTS 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 262 IATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIdikrmddPECYFNS 341
Cdd:PRK05942 225 LLEIPGAKDIGVEFHTLSKTYNMAGWRVGFVVGNRHIIQGLRTLKTNLDYGIFSALQKAAETALQL-------PDSYLQQ 297
|
330 340
....*....|....*....|
gi 1159731393 342 LPKELEVKRDRMVRLLESVG 361
Cdd:PRK05942 298 VQERYRTRRDFLIQGLGELG 317
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
54-447 |
7.28e-22 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 97.03 E-value: 7.28e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 54 IEFTKLAA-----DPSVVNLGQGFPDISPPTYVKEELSKIAAIDSlnqyTRGF---GHPSLVKALSYLYEKLYQ-KQIDS 124
Cdd:PRK06290 30 IKRAKRAAkekhpDMELIDMGVGEPDEMADESVVEVLCEEAKKPE----NRGYadnGIQEFKEAAARYMEKVFGvKDIDP 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 125 NKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKF 204
Cdd:PRK06290 106 VTEVIHSIGSKPALAMLPSCFINPGDVTLMTVPGYPVTGTHTKYYGGEVYNLPLLEE---------NNFLPDLDSIPKDI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 205 NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMWERTITIGSAGKTFSV 284
Cdd:PRK06290 177 KEKAKLLYLNYPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDG-KPLSFLSVPGAKEVGVEIHSLSKAYNM 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 285 TGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPEcyfnsLPKELEVKRDR----MVRLLESV 360
Cdd:PRK06290 256 TGWRLAFVVGNELIVKAFATVKDNNDSGQFIAIQKAGIYA-------LDHPE-----ITEKIREKYSRrldkLVKILNEV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 361 GLKPIVPDGGYFIIADVSLLDPDLSDMKNNEpydyKFVKWMTKHKKLSAIPVSAFCNsetksqfekFVRF--CFIKKDst 438
Cdd:PRK06290 324 GFKAEMPGGTFYLYVKAPKGTKSGIKFENAE----EFSQYLIKEKLISTVPWDDAGH---------FLRFsvTFEAKD-- 388
|
....*....
gi 1159731393 439 LDAAEEIIK 447
Cdd:PRK06290 389 EEEEDRILE 397
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
65-387 |
1.38e-17 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 84.44 E-value: 1.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 65 VVNLGQGFPDISP--PTYVKEELSKIAAIDS--LNQYTRGFGHPSLVKALS-YLYEKL-YQKQIDsnkEILVTVGAYGSL 138
Cdd:PLN00145 54 VLPLGHGDPSAFPcfRTAPEAEDAVAAALRSgkYNSYSTCVGLLPARRAIAeYLSRDLpYELSTD---DIYLTAGCAQAI 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 139 FNTIQALIDEGDEVILIVPFYDCYEpmvrmagATPVFIPLRSKpvYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHN 218
Cdd:PLN00145 131 EIIMSVLAQPGANILLPRPGYPLYE-------ARAVFSGLEVR--HFDLLPERGWEVDLEGVEALADENTVAMVIINPNN 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 219 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpGMWERTITIGSAGKTFSVTGWKLGW--SIGPN 296
Cdd:PLN00145 202 PCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGSKPFVPMGVF-GEVAPVLTLGSISKRWVVPGWRLGWiaTCDPN 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 297 HLIKHLQTVQ--QNTIYTCATP---LQEALAQAfwidIKRMDDPecYFNSLPKELEVKRDRMVRLLESV-GLK-PIVPDG 369
Cdd:PLN00145 281 GILKETKVVDsiRNYLNISTDPatfVQGAIPQI----IANTKEE--FFTKTLGLLKETADICYEKIKEIkCITcPHKPEG 354
|
330 340
....*....|....*....|
gi 1159731393 370 GYFIIA--DVSLLDPDLSDM 387
Cdd:PLN00145 355 SMFVMVklDLSCLSGIKDDM 374
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
55-378 |
4.40e-17 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 82.49 E-value: 4.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 55 EFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLvKALSYLYEKLyqkqidSNKEILVTVGA 134
Cdd:PRK06225 20 FFDYVFKDKEMIWMGQNTNHLGPHEEVREAMIRCIEEGEYCKYPPPEGFPEL-RELILKDLGL------DDDEALITAGA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 135 YGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATpvfipLRSKPVYGkrwSSSDWTLDPQELESKFNSKTKAIILN 214
Cdd:PRK06225 93 TESLYLVMRAFLSPGDNAVTPDPGYLIIDNFASRFGAE-----VIEVPIYS---EECNYKLTPELVKENMDENTRLIYLI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 215 TPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEwlVYSGNKHLKIATFPgmwERTITIGSAGKTFSVTGWKLGWSIG 294
Cdd:PRK06225 165 DPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYR--DFAREHTLAAEYAP---EHTVTSYSFSKIFGMAGLRIGAVVA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 295 PNHLIKHLQTVQQNTIYTCATPLQEALA----QAFWID-IKRmddpECYFNslpKELeVKrdRMVRLLESVGLkPIVPDG 369
Cdd:PRK06225 240 TPDLIEVVKSIVINDLGTNVIAQEAAIAglkvKDEWIDrIRR----TTFKN---QKL-IK--EAVDEIEGVFL-PVYPSH 308
|
....*....
gi 1159731393 370 GYFIIADVS 378
Cdd:PRK06225 309 GNMMVIDIS 317
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
68-351 |
6.49e-16 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 78.96 E-value: 6.49e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 68 LGQGFPDISPPTYVKEELSKIAAidSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQ-ALI 146
Cdd:PRK05839 29 LTIGEPQFETPKFIQDALKNNAH--LLNKYPKSAGEESLREAQRGFFKRRFKIELKEN-ELIPTFGTREVLFNFPQfVLF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 147 DEGDEVILIV-PFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWT--LDPQELeskfnSKTKAIILNTPHNPLGKV 223
Cdd:PRK05839 106 DKQNPTIAYPnPFYQIYEGAAIASRAKVLLMPLTK---------ENDFTpsLNEKEL-----QEVDLVILNSPNNPTGRT 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 224 YNREELQVIADLCIKYDTLCISDEVY-------------EWLVYSGNKHLKiatfpgmweRTITIGSAGKTFSVTGWKLG 290
Cdd:PRK05839 172 LSLEELIEWVKLALKHDFILINDECYseiyentpppsllEASILVGNESFK---------NVLVINSISKRSSAPGLRSG 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1159731393 291 WSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfWIDikrMDDPECYFNSLPKELEVKRD 351
Cdd:PRK05839 243 FIAGDASILKKYKAYRTYLGCASPLPLQKAAAVA-WLD---DEHAEFFRNIYAKNLKLARE 299
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
64-291 |
4.76e-15 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 76.50 E-value: 4.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 64 SVVNLGQGFPDISP---PTYVKEElskiAAIDSL-----NQYTRGFGHPSLVKALS-YLYEKLYQKQidSNKEILVTVGA 134
Cdd:PLN02656 32 RVISLGMGDPTAYScfhTTHVAQE----AVVDALqsnkfNGYAPTVGLPQARRAIAeYLSRDLPYKL--SLDDVFITSGC 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 135 YGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskPVYGkrwsssdWTLDPQELESKFNSKTKAIILN 214
Cdd:PLN02656 106 TQAIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVRYVDLL--PEKG-------WEVDLDAVEALADQNTVALVII 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1159731393 215 TPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpGMWERTITIGSAGKTFSVTGWKLGW 291
Cdd:PLN02656 177 NPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFVPMGVF-GSIVPVLTLGSLSKRWIVPGWRLGW 252
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
124-411 |
5.72e-15 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 76.59 E-value: 5.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 124 SNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMvrmagATPVFIPLRSKPVYGKRwsssDWTLDPQELESK 203
Cdd:PLN00143 96 SPDDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVETY-----AIFHHLEIRHFDLLPEK----GWEVDLDAVEAI 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 204 FNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpGMWERTITIGSAGKTFS 283
Cdd:PLN00143 167 ADENTIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPFVPMGLF-ASIVPVITLGSISKRWM 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 284 VTGWKLGWSI--GPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECY---FNSLPKELEVKRDRMVRLle 358
Cdd:PLN00143 246 IPGWGLGWLVtcDPSGLLQICEIADSIKKALNPAPFPPTFIQAAIPEILEKTTEDFFsktINILRAALAFCYDKLKEI-- 323
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1159731393 359 SVGLKPIVPDGGYFIIADVSLLdpDLSDMKNnepyDYKFVKWMTKHKKLSAIP 411
Cdd:PLN00143 324 PCIMCPQKAEGAFFALVKLNLL--LLEDIED----DMEFCLKLAKEESLIILP 370
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
44-375 |
3.43e-14 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 73.97 E-value: 3.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 44 RIEGLDSNVWIEFT--KLA---ADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLY 118
Cdd:PRK08636 9 KIKRLPKYVFAEVNelKMAarrAGEDIIDFSMGNPDGPTPQHIIDKLCESAQKPKTHGYSVSKGIYKLRLAICNWYKRKY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 119 QKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvygkrwSSSDWTLDPQ 198
Cdd:PRK08636 89 NVDLDPETEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYPIHSQAFILAGGNVHKMPLE---------YNEDFELDED 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 199 E----LESKFNS---KTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWER 271
Cdd:PRK08636 160 QffenLEKALREsspKPKYVVVNFPHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKTPSILEVEGAKDV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 272 TITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRD 351
Cdd:PRK08636 240 AVESYTLSKSYNMAGWRVGFVVGNKKLVGALKKIKSWLDYGMFTPIQVAATIA-------LDGDQSCVEEIRETYRKRRD 312
|
330 340
....*....|....*....|....
gi 1159731393 352 RMVRLLESVGLKPIVPDGGYFIIA 375
Cdd:PRK08636 313 VLIESFANAGWELQKPRASMFVWA 336
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
56-249 |
6.67e-14 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 72.98 E-value: 6.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 56 FTKLA---------ADPSVVNLGQGFPDISPPTYVKEELskIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQ-IDSN 125
Cdd:PRK09147 13 FEKLRalfagvtppADLPPISLSIGEPKHPTPAFIKDAL--AANLDGLASYPTTAGLPALREAIAAWLERRYGLPaLDPA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 126 KEILVTVGAYGSLFNTIQALIDEGDEVILIV---PFYDCYEPMVRMAGATPVFIPlrSKPvygKRWSSSDWTLDPQELEs 202
Cdd:PRK09147 91 TQVLPVNGSREALFAFAQTVIDRDGPGPLVVcpnPFYQIYEGAALLAGAEPYFLN--CDP---ANNFAPDFDAVPAEVW- 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1159731393 203 kfnSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVY 249
Cdd:PRK09147 165 ---ARTQLLFVCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECY 208
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
62-321 |
6.74e-13 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 70.14 E-value: 6.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 62 DPSVVNLGQGFPDISP--PTYVKEELSKIAAIDSL--NQYTRGFG-HPSLVKALSYLYEKLYQKQidSNKEILVTVGAYG 136
Cdd:PLN02187 65 NKTILPLGHGDPSVYPcfRTCIEAEDAVVDVLRSGkgNSYGPGAGiLPARRAVADYMNRDLPHKL--TPEDIFLTAGCNQ 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 137 SLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGatpvfIPLRSKPVYGKRwsssDWTLDPQELESKFNSKTKAIILNTP 216
Cdd:PLN02187 143 GIEIVFESLARPNANILLPRPGFPHYDARAAYSG-----LEVRKFDLLPEK----EWEIDLEGIEAIADENTVAMVVINP 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 217 HNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWErTITIGSAGKTFSVTGWKLGWSI--- 293
Cdd:PLN02187 214 NNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVP-VLTLAGISKGWVVPGWKIGWIAlnd 292
|
250 260 270
....*....|....*....|....*....|..
gi 1159731393 294 --GPNHLIKHLQTVQQNTIYT--CATPLQEAL 321
Cdd:PLN02187 293 peGVFETTKVLQSIKQNLDVTpdPATIIQAAL 324
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
42-306 |
1.57e-12 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 68.94 E-value: 1.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 42 AKRIEGLDSNVWIEFTK-----LAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEK 116
Cdd:PRK07366 4 AQRLQPLQSNVFADMDRakaqaRAAGKELIDLSLGSSDLPAPAHALEAIAQSLHDPSTHGYLLFHGTLDFREAAAQWYEQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 117 LYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSK----PVygkrwsssd 192
Cdd:PRK07366 84 RFGLAVDPETEVLPLIGSQEGTAHLPLAVLNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPLRAEndflPV--------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 193 WTLDPQELESKfnskTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKiATFPGMWERT 272
Cdd:PRK07366 155 FADIPTEVLAQ----ARLMVLSYPHNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGEVEPP-SILQADPEKS 229
|
250 260 270
....*....|....*....|....*....|....*.
gi 1159731393 273 ITIG--SAGKTFSVTGWKLGWSIGPNHLIKHLQTVQ 306
Cdd:PRK07366 230 VSIEffTLSKSYNMGGFRIGFAIGNAQLIQALRQVK 265
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
192-291 |
1.45e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 66.13 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 192 DWTLDPQELES--KFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF---- 265
Cdd:PRK06855 154 NWYPDLDDLENkvKYNPSIAGILLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVPLSEVigdv 233
|
90 100
....*....|....*....|....*.
gi 1159731393 266 PGMWERTITigsagKTFSVTGWKLGW 291
Cdd:PRK06855 234 PGIALKGIS-----KELPWPGSRCGW 254
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
97-258 |
1.28e-10 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 63.06 E-value: 1.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 97 YTRGFGHPSLVKALSYLYEKL--YQKQIDSnkeILVTVGAYGSLFNTIQALI-DEGDEVILIVPFYDCYEPMVRMAGATP 173
Cdd:PTZ00377 111 YTDSAGYPFVRKAVAAFIERRdgVPKDPSD---IFLTDGASSGIKLLLQLLIgDPSDGVMIPIPQYPLYSAAITLLGGKQ 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 174 VFIPLRSkpvygkrwsSSDWTLDPQELESKF------NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDE 247
Cdd:PTZ00377 188 VPYYLDE---------EKGWSLDQEELEEAYeqavrnGITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADE 258
|
170
....*....|.
gi 1159731393 248 VYEWLVYSGNK 258
Cdd:PTZ00377 259 VYQENIYDGEK 269
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
104-378 |
6.90e-09 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 57.40 E-value: 6.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 104 PSLVKALS-----YLYEKLYQKQI------DSNKE---ILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMA 169
Cdd:PLN03026 68 PEVLEALGnmkfpYVYPDPESRRLraalaeDSGLEsenILVGCGADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 170 GATPVFIPLrskpvygkrwsSSDWTLD-PQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIkydtLCISDEV 248
Cdd:PLN03026 148 GAEVIKVPR-----------TPDFSLDvPRIVEAVETHKPKLLFLTSPNNPDGSIISDDDLLKILELPI----LVVLDEA 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 249 YewLVYSGNK-HLKIATfpgMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNtiYTCATPLQEALAQAFwi 327
Cdd:PLN03026 213 Y--IEFSTQEsRMKWVK---KYDNLIVLRTFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQP--YNVSVAAEVAACAAL-- 283
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1159731393 328 dikrmDDPEcYFNSLPKELEVKRDRMVRLLESVG-LKPIvPDGGYFIIADVS 378
Cdd:PLN03026 284 -----SNPK-YLEDVKNALVEERERLFGLLKEVPfLEPY-PSDANFILCRVT 328
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
102-290 |
9.80e-09 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 57.21 E-value: 9.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 102 GHPSLVKALSYLYEKLY--QKQIDSNKeILVTVGAYGS--LFNTIqaLIDEGDEVILIVPFYDCYEPMVRMAGATPVfIP 177
Cdd:PLN02607 96 GLKSFRQAMASFMEQIRggKARFDPDR-IVLTAGATAAneLLTFI--LADPGDALLVPTPYYPGFDRDLRWRTGVKI-VP 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 178 LRSKpvygkrwSSSDWTLDPQELESKF------NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEW 251
Cdd:PLN02607 172 IHCD-------SSNNFQVTPQALEAAYqeaeaaNIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSG 244
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1159731393 252 LVYSGNKHLKIAT------FPGMWERTITIGSAGKTFSVTGWKLG 290
Cdd:PLN02607 245 SVFSASEFVSVAEiveargYKGVAERVHIVYSLSKDLGLPGFRVG 289
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
94-254 |
1.18e-07 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 53.65 E-value: 1.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 94 LNQYTRGFGHPSLVKALSYLYEKlyQKQIDSNKE-ILVTVGAYGSLFNTIQALI-DEGDEVILIVPFYDCYEPMVRMAGA 171
Cdd:PLN02368 100 LGAYSDSRGLPGVRKEVAEFIER--RDGYPSDPElIFLTDGASKGVMQILNAVIrGEKDGVLVPVPQYPLYSATISLLGG 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 172 TPVfiplrskPVYGKRwsSSDWTLDPQELESKFNSK------TKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCIS 245
Cdd:PLN02368 178 TLV-------PYYLEE--SENWGLDVNNLRQSVAQArskgitVRAMVIINPGNPTGQCLSEANLREILKFCYQERLVLLG 248
|
....*....
gi 1159731393 246 DEVYEWLVY 254
Cdd:PLN02368 249 DEVYQQNIY 257
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
130-229 |
1.53e-07 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 53.05 E-value: 1.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 130 VTVGAyGS---LFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvygkrwssSDWTLDPQELESKFNS 206
Cdd:PRK03321 77 VAVGC-GSvalCQQLVQATAGPGDEVIFAWRSFEAYPILVQVAGATPVQVPLT-----------PDHTHDLDAMAAAITD 144
|
90 100
....*....|....*....|...
gi 1159731393 207 KTKAIILNTPHNPLGKVYNREEL 229
Cdd:PRK03321 145 RTRLIFVCNPNNPTGTVVTPAEL 167
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
126-263 |
3.34e-07 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 52.39 E-value: 3.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 126 KEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVR-MAGATPVFIPLRSKPVYGKRWSSSDWTLDPQElESkf 204
Cdd:PLN02376 120 ERVVMSGGATGANETIMFCLADPGDVFLIPSPYYAAFDRDLRwRTGVEIIPVPCSSSDNFKLTVDAADWAYKKAQ-ES-- 196
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1159731393 205 NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIA 263
Cdd:PLN02376 197 NKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVFAGGDFVSVA 255
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
127-277 |
5.05e-07 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 51.86 E-value: 5.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 127 EILVTVGAYGSLFNTIQALI-DEGDEVILIVPFYDCYEPMVRMAGATPVfiplrskPVYGKRwsSSDWTLDPQELESKF- 204
Cdd:PLN02231 193 DIFLTDGASPAVHMMMQLLIrSEKDGILCPIPQYPLYSASIALHGGTLV-------PYYLDE--ATGWGLEISELKKQLe 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 205 NSKTK-----AIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHL----KIATFPGMWERTITI 275
Cdd:PLN02231 264 DARSKgitvrALVVINPGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVYVPDKKFhsfkKVARSMGYGEKDISL 343
|
..
gi 1159731393 276 GS 277
Cdd:PLN02231 344 VS 345
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
142-212 |
2.16e-06 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 49.68 E-value: 2.16e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1159731393 142 IQAL-IDEGDEVIliVP---FYDCYEPmVRMAGATPVFI---PlrskpvygkrwssSDWTLDPQELESKFNSKTKAII 212
Cdd:COG0399 62 LRALgIGPGDEVI--TPaftFVATANA-ILYVGATPVFVdidP-------------DTYNIDPEALEAAITPRTKAII 123
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
93-294 |
5.73e-06 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 48.19 E-value: 5.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 93 SLNQYTRGFGHPSLVKALSYLYEKLYQKQIDS------NKEILVTVGAYGSLFnTIQALIDEGDEVILIVPFYDCYEPMV 166
Cdd:PRK08354 16 SVNPYPPEWLDEMFERAKEISGRYTYYEWLEEefsklfGEPIVITAGITEALY-LIGILALRDRKVIIPRHTYGEYERVA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 167 RMAGAtpvfiplrsKPVYGKrwsssdwtLDPQELEsKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISD 246
Cdd:PRK08354 95 RFFAA---------RIIKGP--------NDPEKLE-ELVERNSVVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLILD 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1159731393 247 EVYEWLVYSGNKhlkiatFPGmwERTITIGSAGKTFSVTGWKLGWSIG 294
Cdd:PRK08354 157 EAFIDFVKKPES------PEG--ENIIKLRTFTKSYGLPGIRVGYVKG 196
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
138-246 |
1.89e-05 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 46.46 E-value: 1.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 138 LFNTIQALIDEGDEVILIvpfYDCYEPMVRM-------AGATPVFIPlrskpvygkrwsssdwTLDPQELESKFNSKTKA 210
Cdd:pfam01053 75 ITAAILALLKAGDHIVAT---DDLYGGTYRLfnkvlprFGIEVTFVD----------------TSDPEDLEAAIKPNTKA 135
|
90 100 110
....*....|....*....|....*....|....*.
gi 1159731393 211 IILNTPHNPLGKVYnreELQVIADLCIKYDTLCISD 246
Cdd:pfam01053 136 VYLETPTNPLLKVV---DIEAIAKLAKKHGILVVVD 168
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
146-246 |
2.19e-05 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 46.38 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 146 IDEGDEVIliVPfydcyePM--------VRMAGATPVFI---PlrskpvygkrwssSDWTLDPQELESKFNSKTKAIIln 214
Cdd:cd00616 55 IGPGDEVI--VP------SFtfvatanaILLLGATPVFVdidP-------------DTYNIDPELIEAAITPRTKAII-- 111
|
90 100 110
....*....|....*....|....*....|..
gi 1159731393 215 tPHNPLGKVYNREELQVIADlciKYDTLCISD 246
Cdd:cd00616 112 -PVHLYGNPADMDAIMAIAK---RHGLPVIED 139
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
138-290 |
7.00e-05 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 45.24 E-value: 7.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 138 LFNTIQA--LIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPvygkrwsSSDWTLDPQELESKFNSKTKAIILNT 215
Cdd:PRK09275 177 IFDSLKEngLLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADE-------ENEWQYPDSELEKLRDPSIKALFLVN 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 216 PHNPLGKVYNREELQVIADLCIKY--DTLCISDEVYewlvysgnkhlkiATF-PGMweRTI-------TIG--SAGKTFS 283
Cdd:PRK09275 250 PSNPPSVAMSDESLEKIADIVNEKrpDLMIITDDVY-------------GTFvDDF--RSLfavlpynTILvySFSKYFG 314
|
....*..
gi 1159731393 284 VTGWKLG 290
Cdd:PRK09275 315 ATGWRLG 321
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
102-255 |
1.02e-04 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 44.36 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 102 GHPSLVKALSYLYEKL--YQKQIDSNKeILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVR-MAGATPVfiPL 178
Cdd:PLN02450 87 GLPAFKNALAEFMSEIrgNKVTFDPNK-LVLTAGATSANETLMFCLAEPGDAFLLPTPYYPGFDRDLKwRTGVEIV--PI 163
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1159731393 179 RSKPVYGKRWSSSdwTLDPQELES-KFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYS 255
Cdd:PLN02450 164 HCSSSNGFQITES--ALEEAYQQAqKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFD 239
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
124-249 |
1.13e-04 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 42.75 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 124 SNKEILVTVGAYGSLFNTIQALIDEGDEVILIVP-FYDCYEPMVRMAGATPVFIPlrsKPVYGKRwsssdwTLDPQELES 202
Cdd:cd01494 16 GNDKAVFVPSGTGANEAALLALLGPGDEVIVDANgHGSRYWVAAELAGAKPVPVP---VDDAGYG------GLDVAILEE 86
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1159731393 203 KFNSK-TKAIILNTPHNPLGKVYNREElqvIADLCIKYDTLCISDEVY 249
Cdd:cd01494 87 LKAKPnVALIVITPNTTSGGVLVPLKE---IRKIAKEYGILLLVDAAS 131
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
180-246 |
2.32e-04 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 43.15 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 180 SKPVYG----------KRWSSS---DWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNreeLQVIADLCIKYDTLCISD 246
Cdd:PRK08247 96 SSDLYGgtyrlfeehwKKWNVRfvyVNTASLKAIEQAITPNTKAIFIETPTNPLMQETD---IAAIAKIAKKHGLLLIVD 172
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
143-246 |
4.28e-04 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 42.27 E-value: 4.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1159731393 143 QAL-IDEGDEVILiVPF-YDCYEPMVRMAGATPVFIPLrsKPVygkrwsssDWTLDPQELESKFNSKTKAIIlntPHNPL 220
Cdd:pfam01041 57 RALgVGPGDEVIT-PSFtFVATANAALRLGAKPVFVDI--DPD--------TYNIDPEAIEAAITPRTKAII---PVHLY 122
|
90 100
....*....|....*....|....*.
gi 1159731393 221 GKVYnreELQVIADLCIKYDTLCISD 246
Cdd:pfam01041 123 GQPA---DMDAIRAIAARHGLPVIED 145
|
|
| |
