cell surface hyaluronidase CEMIP2 isoform c [Homo sapiens]
ILEI domain-containing protein( domain architecture ID 11238926)
ILEI domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||
ILEI | pfam15711 | Interleukin-like EMT inducer; ILEI is a family of proteins found in vertebrates. It is heavily ... |
606-690 | 9.47e-13 | |||
Interleukin-like EMT inducer; ILEI is a family of proteins found in vertebrates. It is heavily involved in the process of the transition from epithelial to mesenchymal tissue - EMT - during all of embryonic development, cancer progression, metastasis, and chronic inflammation/fibrosis. ILEI is upregulated exclusively at the level of translation, and abnormal ILEI expression, ie cytoplasmic over-expression instead of vesicular localization, is associated with EMT in human cancerous tissue. In order to induce and maintain the EMT of hepatocytes in a TGF-beta-independent fashion ILEI needs the cooperation of oncogenic Ras. : Pssm-ID: 464817 Cd Length: 89 Bit Score: 64.20 E-value: 9.47e-13
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Name | Accession | Description | Interval | E-value | |||
ILEI | pfam15711 | Interleukin-like EMT inducer; ILEI is a family of proteins found in vertebrates. It is heavily ... |
606-690 | 9.47e-13 | |||
Interleukin-like EMT inducer; ILEI is a family of proteins found in vertebrates. It is heavily involved in the process of the transition from epithelial to mesenchymal tissue - EMT - during all of embryonic development, cancer progression, metastasis, and chronic inflammation/fibrosis. ILEI is upregulated exclusively at the level of translation, and abnormal ILEI expression, ie cytoplasmic over-expression instead of vesicular localization, is associated with EMT in human cancerous tissue. In order to induce and maintain the EMT of hepatocytes in a TGF-beta-independent fashion ILEI needs the cooperation of oncogenic Ras. Pssm-ID: 464817 Cd Length: 89 Bit Score: 64.20 E-value: 9.47e-13
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PANDER_like_KIAA1199 | cd13941 | PANDER-like domain of KIAA1199 and similar proteins; KIAA1199 has been characterized as a ... |
587-701 | 3.18e-05 | |||
PANDER-like domain of KIAA1199 and similar proteins; KIAA1199 has been characterized as a protein associated with poor survival when upregulated in human cancer, as well as with nonsyndromic loss of hearing when mutated. It contains a C-terminal domain similar to the Pancreatic-derived factor PANDER; the function of this PANDER-like domain has not been characterized. Pssm-ID: 260115 Cd Length: 157 Bit Score: 44.80 E-value: 3.18e-05
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Name | Accession | Description | Interval | E-value | |||
ILEI | pfam15711 | Interleukin-like EMT inducer; ILEI is a family of proteins found in vertebrates. It is heavily ... |
606-690 | 9.47e-13 | |||
Interleukin-like EMT inducer; ILEI is a family of proteins found in vertebrates. It is heavily involved in the process of the transition from epithelial to mesenchymal tissue - EMT - during all of embryonic development, cancer progression, metastasis, and chronic inflammation/fibrosis. ILEI is upregulated exclusively at the level of translation, and abnormal ILEI expression, ie cytoplasmic over-expression instead of vesicular localization, is associated with EMT in human cancerous tissue. In order to induce and maintain the EMT of hepatocytes in a TGF-beta-independent fashion ILEI needs the cooperation of oncogenic Ras. Pssm-ID: 464817 Cd Length: 89 Bit Score: 64.20 E-value: 9.47e-13
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PANDER_like_KIAA1199 | cd13941 | PANDER-like domain of KIAA1199 and similar proteins; KIAA1199 has been characterized as a ... |
587-701 | 3.18e-05 | |||
PANDER-like domain of KIAA1199 and similar proteins; KIAA1199 has been characterized as a protein associated with poor survival when upregulated in human cancer, as well as with nonsyndromic loss of hearing when mutated. It contains a C-terminal domain similar to the Pancreatic-derived factor PANDER; the function of this PANDER-like domain has not been characterized. Pssm-ID: 260115 Cd Length: 157 Bit Score: 44.80 E-value: 3.18e-05
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Blast search parameters | ||||
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