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Conserved domains on  [gi|1213953156|ref|NP_001340135|]
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centrobin isoform gamma [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
205-559 8.98e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.92  E-value: 8.98e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 205 QSLQTRVLELQQQLAVAvaADRKKDTMIEQLDKTLArvvegwnrheaERTEVLRGLQEEHQAAELTRSKQQETVTRLEQS 284
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE-----------ELEAELEELEAELAELEAELEELRLELEELELE 282
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 285 LSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQ 364
Cdd:COG1196   283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 365 QEHQLKEHYQALQEEsQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQR 444
Cdd:COG1196   363 AEEALLEAEAELAEA-EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 445 IQLESELAVQLEQrvtERLAQAQESSLRQAASLREHHRKQLQDLsgqhQQELASQLAQFKVEMAEREERQQQVAEDYELR 524
Cdd:COG1196   442 EALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1213953156 525 LAREQARVC-ELQSGNQQLEEQRVELVERLQAMLQA 559
Cdd:COG1196   515 LLAGLRGLAgAVAVLIGVEAAYEAALEAALAAALQN 550
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
205-559 8.98e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.92  E-value: 8.98e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 205 QSLQTRVLELQQQLAVAvaADRKKDTMIEQLDKTLArvvegwnrheaERTEVLRGLQEEHQAAELTRSKQQETVTRLEQS 284
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE-----------ELEAELEELEAELAELEAELEELRLELEELELE 282
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 285 LSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQ 364
Cdd:COG1196   283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 365 QEHQLKEHYQALQEEsQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQR 444
Cdd:COG1196   363 AEEALLEAEAELAEA-EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 445 IQLESELAVQLEQrvtERLAQAQESSLRQAASLREHHRKQLQDLsgqhQQELASQLAQFKVEMAEREERQQQVAEDYELR 524
Cdd:COG1196   442 EALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1213953156 525 LAREQARVC-ELQSGNQQLEEQRVELVERLQAMLQA 559
Cdd:COG1196   515 LLAGLRGLAgAVAVLIGVEAAYEAALEAALAAALQN 550
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
198-488 5.32e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 5.32e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  198 KHCERHIQSLQTRVLELQQQLAVAvaadRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQET 277
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAEL----RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  278 VTRLEQSLSEAMEALNREQESARLQQRERETLEEE-------RQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELET 350
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQieqlkeeLKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  351 LRAALEEERQTWAQQEHQLK------EHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARR 424
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIEslaaeiEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRR 915
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156  425 ERDALQLEMSLVQARY---ESQRIQLESELAV--QLEQRVTERLAQAQESSLRQAASLREHHRKQLQDL 488
Cdd:TIGR02168  916 ELEELREKLAQLELRLeglEVRIDNLQERLSEeySLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
mukB PRK04863
chromosome partition protein MukB;
235-567 5.61e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 60.36  E-value: 5.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  235 LDKTLARVVEGWNRHEAERTEVLRG---LQEEHQAAELTRSKQQETVTR--------------LEQSLSEAMEALNREQE 297
Cdd:PRK04863   263 ITESTNYVAADYMRHANERRVHLEEaleLRRELYTSRRQLAAEQYRLVEmarelaelneaesdLEQDYQAASDHLNLVQT 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  298 sARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALE------EERQTWAQQEHQLKe 371
Cdd:PRK04863   343 -ALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLAdyqqalDVQQTRAIQYQQAV- 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  372 hyQALQEESQ-------------AQLEREKEKSQREAQAAWETQHQLALVQ----------SEVRRLEGELDTARRERDA 428
Cdd:PRK04863   421 --QALERAKQlcglpdltadnaeDWLEEFQAKEQEATEELLSLEQKLSVAQaahsqfeqayQLVRKIAGEVSRSEAWDVA 498
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  429 LQLEmslvqARYESQRIQleselAVQLEQRvterlaQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQlAQFKVEMA 508
Cdd:PRK04863   499 RELL-----RRLREQRHL-----AEQLQQL------RMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDE-DELEQLQE 561
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156  509 EREERQqqvaEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHwDEANQL 567
Cdd:PRK04863   562 ELEARL----ESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQ-DALARL 615
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
201-555 1.68e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 58.70  E-value: 1.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  201 ERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTR 280
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEA 326
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  281 LEqslSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSE-HRELETLRAALEEER 359
Cdd:pfam12128  327 LE---DQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIKDKLAKIR 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  360 QTWAQQEHQLKEHYQALQEESQAQLEREK-----EKSQREAQAAW------------ETQHQLALVQSEVRRLEGELDTA 422
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESELREQLEAGKlefneEEYRLKSRLGElklrlnqatatpELLLQLENFDERIERAREEQEAA 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  423 RRERDALQLEMSLVQARYESQRIQLESELAVQLEQRvtERLAQAQESSLRQAASLREHHRKQLQDLSgQHQQELAS--QL 500
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQ--SALDELELQLFPQAGTLLHFLRKEAPDWE-QSIGKVISpeLL 560
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1213953156  501 AQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQA 555
Cdd:pfam12128  561 HRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQS 615
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
205-559 8.98e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.92  E-value: 8.98e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 205 QSLQTRVLELQQQLAVAvaADRKKDTMIEQLDKTLArvvegwnrheaERTEVLRGLQEEHQAAELTRSKQQETVTRLEQS 284
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE-----------ELEAELEELEAELAELEAELEELRLELEELELE 282
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 285 LSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQ 364
Cdd:COG1196   283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 365 QEHQLKEHYQALQEEsQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQR 444
Cdd:COG1196   363 AEEALLEAEAELAEA-EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 445 IQLESELAVQLEQrvtERLAQAQESSLRQAASLREHHRKQLQDLsgqhQQELASQLAQFKVEMAEREERQQQVAEDYELR 524
Cdd:COG1196   442 EALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1213953156 525 LAREQARVC-ELQSGNQQLEEQRVELVERLQAMLQA 559
Cdd:COG1196   515 LLAGLRGLAgAVAVLIGVEAAYEAALEAALAAALQN 550
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
226-567 8.82e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 8.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 226 RKKDTMiEQLDKT---LARVvegwnrhEAERTEV---LRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESA 299
Cdd:COG1196   173 RKEEAE-RKLEATeenLERL-------EDILGELerqLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEEL 244
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 300 RLQQRERETLEEerqaltlRLEAEQQRccvLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLkEHYQALQEE 379
Cdd:COG1196   245 EAELEELEAELE-------ELEAELAE---LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI-ARLEERRRE 313
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 380 SQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRV 459
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 460 TERLAQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVcELQSGN 539
Cdd:COG1196   394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA-ELLEEA 472
                         330       340
                  ....*....|....*....|....*...
gi 1213953156 540 QQLEEQRVELVERLQAMLQAHWDEANQL 567
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAE 500
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
198-488 5.32e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 5.32e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  198 KHCERHIQSLQTRVLELQQQLAVAvaadRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQET 277
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAEL----RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  278 VTRLEQSLSEAMEALNREQESARLQQRERETLEEE-------RQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELET 350
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQieqlkeeLKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  351 LRAALEEERQTWAQQEHQLK------EHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARR 424
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIEslaaeiEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRR 915
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156  425 ERDALQLEMSLVQARY---ESQRIQLESELAV--QLEQRVTERLAQAQESSLRQAASLREHHRKQLQDL 488
Cdd:TIGR02168  916 ELEELREKLAQLELRLeglEVRIDNLQERLSEeySLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
314-599 6.24e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 6.24e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 314 QALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQR 393
Cdd:COG1196   214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 394 EAQAAwETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQ 473
Cdd:COG1196   294 LAELA-RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 474 AASLREHHRKQLQDLSGQHQQELASQLAQfkvemaerEERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERL 553
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAAELAAQ--------LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1213953156 554 QAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRV 599
Cdd:COG1196   445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
284-558 8.24e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 8.24e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  284 SLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSE--HRELETLRAALEEERQT 361
Cdd:TIGR02168  665 SAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqISALRKDLARLEAEVEQ 744
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  362 WAQQEHQLkehyQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYE 441
Cdd:TIGR02168  745 LEERIAQL----SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  442 SQRIQLESEL--AVQLEQRVTERLAQAQESSLRQAASlrEHHRKQLQDLSGQHQQELAS---QLAQFKVEMAEREERQQQ 516
Cdd:TIGR02168  821 NLRERLESLErrIAATERRLEDLEEQIEELSEDIESL--AAEIEELEELIEELESELEAllnERASLEEALALLRSELEE 898
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1213953156  517 VAEdyELRLAREQARvcELQSGNQQLEEQRVELVERLQAMLQ 558
Cdd:TIGR02168  899 LSE--ELRELESKRS--ELRRELEELREKLAQLELRLEGLEV 936
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
328-559 1.44e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 68.40  E-value: 1.44e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  328 CVLQEERDAARAGQLSEH-RELETLRAALEEERQtwaQQEH--QLKEHYQALQEesqAQLEREKEKSQREAQAAWETQHQ 404
Cdd:COG4913    216 YMLEEPDTFEAADALVEHfDDLERAHEALEDARE---QIELlePIRELAERYAA---ARERLAELEYLRAALRLWFAQRR 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  405 LALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQrvTERLAQAQESSLRQAASLREHHRKQ 484
Cdd:COG4913    290 LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ--LEREIERLERELEERERRRARLEAL 367
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  485 LQDLSGQHQ------QELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQ 558
Cdd:COG4913    368 LAALGLPLPasaeefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447

                   .
gi 1213953156  559 A 559
Cdd:COG4913    448 A 448
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
250-543 3.72e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 3.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  250 EAERTEVLRGLQEEHQAAELT------------RSKQQETVTRLEQSLSEAMEALNREQES---ARLQQRERETLEEERQ 314
Cdd:TIGR02168  208 QAEKAERYKELKAELRELELAllvlrleelreeLEELQEELKEAEEELEELTAELQELEEKleeLRLEVSELEEEIEELQ 287
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  315 ALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKsqRE 394
Cdd:TIGR02168  288 KELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL--EA 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  395 AQAAWETQhqlalvqseVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLEselavQLEQRVtERLAQAQESslrQA 474
Cdd:TIGR02168  366 ELEELESR---------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE-----RLEDRR-ERLQQEIEE---LL 427
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1213953156  475 ASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAE------DYELRLAREQARVCELQSGNQQLE 543
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEaeqaldAAERELAQLQARLDSLERLQENLE 502
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
180-552 1.98e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 1.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  180 PPDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEgwnrheaERTEVLRG 259
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE-------RLEELEED 745
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  260 LQEEHQAAELTRSKQQEtvtrLEQSLSEAMEALNREQES-ARLQQRERETLEEERQALTLRLEAEQQRccvlQEERDAAR 338
Cdd:TIGR02169  746 LSSLEQEIENVKSELKE----LEARIEELEEDLHKLEEAlNDLEARLSHSRIPEIQAELSKLEEEVSR----IEARLREI 817
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  339 AGQLSEhreLETLRAALEEERQTWAQQEHQLKEHYQALQEEsQAQLEREKEKSQREaqaawetqhqLALVQSEVRRLEGE 418
Cdd:TIGR02169  818 EQKLNR---LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-IENLNGKKEELEEE----------LEELEAALRDLESR 883
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  419 LDTARRERDALQLEMSLVQARYESQRIQLEselavQLEQRVTERLAQAQEsslrQAASLREHHRKQLQDLSGQHQQELAS 498
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIE-----KKRKRLSELKAKLEA----LEEELSEIEDPKGEDEEIPEEELSLE 954
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1213953156  499 QLAQFKVEMAEREERQQQV----AEDYElrlaREQARVCELQSGNQQLEEQRVELVER 552
Cdd:TIGR02169  955 DVQAELQRVEEEIRALEPVnmlaIQEYE----EVLKRLDELKEKRAKLEEERKAILER 1008
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
251-551 1.50e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 1.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  251 AERTEVLRgLQEEHQAAELTRSKQQETVTRLEQSLSEA---MEALNREQESARLQQRERETLEEERQALTLRLEAEQQRC 327
Cdd:TIGR02169  671 SEPAELQR-LRERLEGLKRELSSLQSELRRIENRLDELsqeLSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  328 cvlQEERDAARAgqlsehrELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKsqreaqaawetqhqlal 407
Cdd:TIGR02169  750 ---EQEIENVKS-------ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK----------------- 802
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  408 VQSEVRRLEGELDTARRERDALQLEMslvqaRYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLRE--HHRKQL 485
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEK-----EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEleELEAAL 877
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156  486 QDLSGQHqQELASQLAQFKVEMAEREERQQQVAEDYEL---RLAREQARVCELQSGNQQLEEQRVELVE 551
Cdd:TIGR02169  878 RDLESRL-GDLKKERDELEAQLRELERKIEELEAQIEKkrkRLSELKAKLEALEEELSEIEDPKGEDEE 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
334-559 2.84e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 2.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  334 RDAARAGQLSEHRELETLRAALEEerqtwaqQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAwETQHQLALVQSEVR 413
Cdd:TIGR02168  665 SAKTNSSILERRREIEELEEKIEE-------LEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLA 736
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  414 RLEGELDTARRERDALQLEMSLVQAR---YESQRIQLESELAVQLEQRVT--ERLAQAQEsslrQAASLREHH---RKQL 485
Cdd:TIGR02168  737 RLEAEVEQLEERIAQLSKELTELEAEieeLEERLEEAEEELAEAEAEIEEleAQIEQLKE----ELKALREALdelRAEL 812
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1213953156  486 QDLSG-QHQQELASQLAQFKVEMAERE-ERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQA 559
Cdd:TIGR02168  813 TLLNEeAANLRERLESLERRIAATERRlEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
313-553 5.28e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 5.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  313 RQALTLRLEAEQQRCCVLQEERDAARAgQLSEHRELETLRAAlEEERQTWAQQEHQLKEHYQALQEESQ--AQLEREKEK 390
Cdd:COG4913    619 LAELEEELAEAEERLEALEAELDALQE-RREALQRLAEYSWD-EIDVASAEREIAELEAELERLDASSDdlAALEEQLEE 696
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  391 SQREAQAAwetQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYES-QRIQLESELAVQLEQRVTERLAQAQES 469
Cdd:COG4913    697 LEAELEEL---EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVERELRENLEE 773
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  470 SLRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREE----RQQQVAED--------YELRLAREQARVCELQS 537
Cdd:COG4913    774 RIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEylalLDRLEEDGlpeyeerfKELLNENSIEFVADLLS 853
                          250
                   ....*....|....*.
gi 1213953156  538 gnqQLEEQRVELVERL 553
Cdd:COG4913    854 ---KLRRAIREIKERI 866
mukB PRK04863
chromosome partition protein MukB;
235-567 5.61e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 60.36  E-value: 5.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  235 LDKTLARVVEGWNRHEAERTEVLRG---LQEEHQAAELTRSKQQETVTR--------------LEQSLSEAMEALNREQE 297
Cdd:PRK04863   263 ITESTNYVAADYMRHANERRVHLEEaleLRRELYTSRRQLAAEQYRLVEmarelaelneaesdLEQDYQAASDHLNLVQT 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  298 sARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALE------EERQTWAQQEHQLKe 371
Cdd:PRK04863   343 -ALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLAdyqqalDVQQTRAIQYQQAV- 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  372 hyQALQEESQ-------------AQLEREKEKSQREAQAAWETQHQLALVQ----------SEVRRLEGELDTARRERDA 428
Cdd:PRK04863   421 --QALERAKQlcglpdltadnaeDWLEEFQAKEQEATEELLSLEQKLSVAQaahsqfeqayQLVRKIAGEVSRSEAWDVA 498
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  429 LQLEmslvqARYESQRIQleselAVQLEQRvterlaQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQlAQFKVEMA 508
Cdd:PRK04863   499 RELL-----RRLREQRHL-----AEQLQQL------RMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDE-DELEQLQE 561
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156  509 EREERQqqvaEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHwDEANQL 567
Cdd:PRK04863   562 ELEARL----ESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQ-DALARL 615
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
201-555 1.68e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 58.70  E-value: 1.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  201 ERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTR 280
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEA 326
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  281 LEqslSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSE-HRELETLRAALEEER 359
Cdd:pfam12128  327 LE---DQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIKDKLAKIR 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  360 QTWAQQEHQLKEHYQALQEESQAQLEREK-----EKSQREAQAAW------------ETQHQLALVQSEVRRLEGELDTA 422
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESELREQLEAGKlefneEEYRLKSRLGElklrlnqatatpELLLQLENFDERIERAREEQEAA 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  423 RRERDALQLEMSLVQARYESQRIQLESELAVQLEQRvtERLAQAQESSLRQAASLREHHRKQLQDLSgQHQQELAS--QL 500
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQ--SALDELELQLFPQAGTLLHFLRKEAPDWE-QSIGKVISpeLL 560
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1213953156  501 AQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQA 555
Cdd:pfam12128  561 HRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQS 615
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
336-555 2.22e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 2.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 336 AARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQeesqaQLEREKEKSQREAQaawETQHQLALVQSEVRRL 415
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-----ALERRIAALARRIR---ALEQELAALEAELAEL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 416 EGELDTARRERDALQLEMS-LVQARYESQRIQ-----LESELAVQLEQRVT--ERLAQAQESSLRQAASLREHHRKQLQD 487
Cdd:COG4942    89 EKEIAELRAELEAQKEELAeLLRALYRLGRQPplallLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAE 168
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 488 LSGQHQQ--ELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQA 555
Cdd:COG4942   169 LEAERAEleALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
196-534 3.14e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.67  E-value: 3.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  196 RRKHCERHIQSLQTRVLELQQQLAVAVAADRKK-DTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQ 274
Cdd:TIGR00618  159 KAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSlHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQT 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  275 QETVTRLEQSLSEAMEALNREQEsARLQQRERETLEEERQALTLRLEAEQQRCCVLQ--------EERDAARAGQLSEHR 346
Cdd:TIGR00618  239 QQSHAYLTQKREAQEEQLKKQQL-LKQLRARIEELRAQEAVLEETQERINRARKAAPlaahikavTQIEQQAQRIHTELQ 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  347 ELETLRAALEEERQTWAQQEHQLKEHYQALQ----EESQAQLEREKEKSQRE--AQAAWETQHQLALvQSEVRRLEGELD 420
Cdd:TIGR00618  318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQtlhsQEIHIRDAHEVATSIREisCQQHTLTQHIHTL-QQQKTTLTQKLQ 396
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  421 TARRERDALQLEMSLVQARYESQRIqLESELAV-----QLEQRVTERLAQAQESSLrQAASLREHHRKQLQdlsgQHQQE 495
Cdd:TIGR00618  397 SLCKELDILQREQATIDTRTSAFRD-LQGQLAHakkqqELQQRYAELCAAAITCTA-QCEKLEKIHLQESA----QSLKE 470
                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1213953156  496 LASQLAQFKVeMAEREERQQQVAEDYELRLAREQARVCE 534
Cdd:TIGR00618  471 REQQLQTKEQ-IHLQETRKKAVVLARLLELQEEPCPLCG 508
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
317-567 3.24e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 3.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  317 TLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTwAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQ 396
Cdd:TIGR02169  669 SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD-ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  397 aawETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQEssLRQAAS 476
Cdd:TIGR02169  748 ---SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLRE--IEQKLN 822
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  477 LREHHRKQLQDLSgqhqQELASQLAQFKVEMAEREERQqqvaEDYELRLAREQARVCELQSGNQQLEEQRVEL---VERL 553
Cdd:TIGR02169  823 RLTLEKEYLEKEI----QELQEQRIDLKEQIKSIEKEI----ENLNGKKEELEEELEELEAALRDLESRLGDLkkeRDEL 894
                          250
                   ....*....|....
gi 1213953156  554 QAMLQAHWDEANQL 567
Cdd:TIGR02169  895 EAQLRELERKIEEL 908
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
263-556 3.41e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 57.44  E-value: 3.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 263 EHQAAeLTRSKQQETVTRLEQS-LSEAMEALNREQESAR-LQQRERETLEEERQALTLRleAEQQRCcVLQEERDAARAG 340
Cdd:pfam17380 279 QHQKA-VSERQQQEKFEKMEQErLRQEKEEKAREVERRRkLEEAEKARQAEMDRQAAIY--AEQERM-AMERERELERIR 354
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 341 QLSEHRELETLRA---ALEEERQ---TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRR 414
Cdd:pfam17380 355 QEERKRELERIRQeeiAMEISRMrelERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 415 LEGELDTARRERdalqlEMSLVQARyESQRIQLESELAVQLEQRVTERLAQAQESSLRQAAslREHHRKQLQDLSGQHQQ 494
Cdd:pfam17380 435 REVRRLEEERAR-----EMERVRLE-EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRA--EEQRRKILEKELEERKQ 506
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1213953156 495 ELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVE---RLQAM 556
Cdd:pfam17380 507 AMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEersRLEAM 571
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
182-572 8.02e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 8.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 182 DFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVA------VAADRKKDTMIEQLDKTLARVVEgWNRHEAERTE 255
Cdd:COG4717    89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLplyqelEALEAELAELPERLEELEERLEE-LRELEEELEE 167
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 256 VLRGLQEEHQ----AAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQ 331
Cdd:COG4717   168 LEAELAELQEeleeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKE 247
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 332 EERDAARAGQLSehrELETLRAALEEERQTWA------------QQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAW 399
Cdd:COG4717   248 ARLLLLIAAALL---ALLGLGGSLLSLILTIAgvlflvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 400 ETQHQLALVQS-----EVRRLEGELDTARRERDALQLEMSLvqARYESQRIQLESELAVQLEQRVTERLAQAQEssLRQA 474
Cdd:COG4717   325 LAALGLPPDLSpeellELLDRIEELQELLREAEELEEELQL--EELEQEIAALLAEAGVEDEEELRAALEQAEE--YQEL 400
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 475 ASLREHHRKQLQDLSGQHQQ--------ELASQLAQFKVEMAEREERQQQVAEdyelRLAREQARVCELQSGN--QQLEE 544
Cdd:COG4717   401 KEELEELEEQLEELLGELEEllealdeeELEEELEELEEELEELEEELEELRE----ELAELEAELEQLEEDGelAELLQ 476
                         410       420
                  ....*....|....*....|....*...
gi 1213953156 545 QRVELVERLQAMLQAHwdEANQLLSTTL 572
Cdd:COG4717   477 ELEELKAELRELAEEW--AALKLALELL 502
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
251-569 9.07e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 9.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  251 AERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQreretleeerQALTlRLEaEQQRCCVL 330
Cdd:COG3096    364 EEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQ----------QAVQ-ALE-KARALCGL 431
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  331 qEERDAARAGQlsehrELETLRAALEEERQTWAQQEHQL-------KEHYQALQ---------EESQA-QLEREKEKSQR 393
Cdd:COG3096    432 -PDLTPENAED-----YLAAFRAKEQQATEEVLELEQKLsvadaarRQFEKAYElvckiagevERSQAwQTARELLRRYR 505
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  394 EAQAAWETQHQLALVQSEVRRLEGELDTARRerdaLQLEMSLVQARYESQRIQLESELAVQLEQRvtERLAQAQESSLRQ 473
Cdd:COG3096    506 SQQALAQRLQQLRAQLAELEQRLRQQQNAER----LLEEFCQRIGQQLDAAEELEELLAELEAQL--EELEEQAAEAVEQ 579
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  474 AASLReHHRKQLQDLSGQHQQ------ELASQLAQFKVEMAEREERQQQVAEDYELRLAREQarvcELQSGNQQLEEQRV 547
Cdd:COG3096    580 RSELR-QQLEQLRARIKELAArapawlAAQDALERLREQSGEALADSQEVTAAMQQLLERER----EATVERDELAARKQ 654
                          330       340
                   ....*....|....*....|..
gi 1213953156  548 ELVERLQAMLQAHWDEANQLLS 569
Cdd:COG3096    655 ALESQIERLSQPGGAEDPRLLA 676
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
186-556 1.53e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.33  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 186 LRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARV---VEGWNRHEAERTEVLRGLQE 262
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELeeeEEEEEEALEEAAEEEAELEE 456
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 263 EHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQ---------------------------- 314
Cdd:COG1196   457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkaalllaglrglagavavligveaay 536
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 315 --ALTLRLEAEQQRCCVLQEERDAARAGQLSEHRE--LETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEK 390
Cdd:COG1196   537 eaALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 391 SQREAQAAWE-TQHQLALVQSEVRRLEGELDTARRERDALQL----------EMSLVQARYESQRIQLESELAVQLEQRV 459
Cdd:COG1196   617 VLGDTLLGRTlVAARLEAALRRAVTLAGRLREVTLEGEGGSAggsltggsrrELLAALLEAEAELEELAERLAEEELELE 696
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 460 TERLAQAQEsslRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREqarvcelqsgn 539
Cdd:COG1196   697 EALLAEEEE---ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL----------- 762
                         410
                  ....*....|....*..
gi 1213953156 540 QQLEEQRVELVERLQAM 556
Cdd:COG1196   763 EELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
346-555 2.38e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 2.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  346 RELETLRAALEEERQTWAQQEHQLKEHYQALQeesqaQLEREKEKSQR--------EAQAAWETQHQLALVQSEVRRLEG 417
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLE-----RLRREREKAERyqallkekREYEGYELLKEKEALERQKEAIER 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  418 ELDTARRERDALQLEMSLVQARYESQRIQLEsELAVQLEQRVTERLAQAQESSLRQAASLREHHRKqlQDLSGQHQQELA 497
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS--IAEKERELEDAE 321
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1213953156  498 SQLAQFKVEMaereERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQA 555
Cdd:TIGR02169  322 ERLAKLEAEI----DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE 375
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
287-467 5.23e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 5.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 287 EAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARagQLSEHRELETLRAALEEERQTWAQQE 366
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--KLLQLLPLYQELEALEAELAELPERL 148
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 367 HQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQ 446
Cdd:COG4717   149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
                         170       180
                  ....*....|....*....|.
gi 1213953156 447 LESELAVQLEQRVTERLAQAQ 467
Cdd:COG4717   229 LEQLENELEAAALEERLKEAR 249
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
226-546 7.49e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 7.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  226 RKKDTMIEQLDKTLARVVEGWN-RHEAERTEVLRGLQEEHQAAEltrskqqetvtRLEQSLSEAMEALNREQESARLQQR 304
Cdd:pfam12128  375 AKYNRRRSKIKEQNNRDIAGIKdKLAKIREARDRQLAVAEDDLQ-----------ALESELREQLEAGKLEFNEEEYRLK 443
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  305 ERETLEEERQA-------LTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLR--------------AALEEERQTWA 363
Cdd:pfam12128  444 SRLGELKLRLNqatatpeLLLQLENFDERIERAREEQEAANAEVERLQSELRQARkrrdqasealrqasRRLEERQSALD 523
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  364 QQEHQL------------------------------------------------------KEHYQALQEESQAQLEREKE 389
Cdd:pfam12128  524 ELELQLfpqagtllhflrkeapdweqsigkvispellhrtdldpevwdgsvggelnlygvKLDLKRIDVPEWAASEEELR 603
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  390 KSQREAQAAWETQHQLAlvqsevRRLEGELDTARRERDALQLEMSLVQARYESQRIQL------ESELAVQLEQRVTERL 463
Cdd:pfam12128  604 ERLDKAEEALQSAREKQ------AAAEEQLVQANGELEKASREETFARTALKNARLDLrrlfdeKQSEKDKKNKALAERK 677
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  464 AQAQEsSLRQAAslrehhrKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGN---- 539
Cdd:pfam12128  678 DSANE-RLNSLE-------AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAkael 749

                   ....*..
gi 1213953156  540 QQLEEQR 546
Cdd:pfam12128  750 KALETWY 756
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
128-555 8.86e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 8.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 128 SERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNPPDFQGLRDALDSEHTRRKHCERHIQSL 207
Cdd:PRK02224  282 RDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEEL 361
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 208 QTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEvlrgLQEEHQAAELTRSKQQETVTRLEQSLSE 287
Cdd:PRK02224  362 REEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGN----AEDFLEELREERDELREREAELEATLRT 437
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 288 AMEALNREQEsarlqqreretleeerqaltLRLEAEQQRCCvlQEERDAARAGQLSEHRE-LETLRAALEEERQTWAQQE 366
Cdd:PRK02224  438 ARERVEEAEA--------------------LLEAGKCPECG--QPVEGSPHVETIEEDRErVEELEAELEDLEEEVEEVE 495
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 367 HQLKEHYQALQEESQAQLEREKEK------SQREAQAAwETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQ--- 437
Cdd:PRK02224  496 ERLERAEDLVEAEDRIERLEERREdleeliAERRETIE-EKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAReev 574
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 438 ARYESQRIQLESELAvQLEqRVTERLAQAQEssLRQAASLREHHRKQLQDLSGQHQQELAsqlaqfkvemaEREERQQQV 517
Cdd:PRK02224  575 AELNSKLAELKERIE-SLE-RIRTLLAAIAD--AEDEIERLREKREALAELNDERRERLA-----------EKRERKREL 639
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 1213953156 518 AEDYElrlareQARVCELQSGNQQLEEQRVELVERLQA 555
Cdd:PRK02224  640 EAEFD------EARIEEAREDKERAEEYLEQVEEKLDE 671
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
274-513 1.08e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 1.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 274 QQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRA 353
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 354 ALEEerqtwaqQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAwetqHQLALVQSEVRRLEGELDTARRERDALQlem 433
Cdd:COG4942    98 ELEA-------QKEELAELLRALYRLGRQPPLALLLSPEDFLDAV----RRLQYLKYLAPARREQAEELRADLAELA--- 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 434 sLVQARYESQRIQLESELAVQLEQRVT-ERLAQAQESSLRQAASLREHHRKQLQDLSGQhQQELASQLAQFKVEMAEREE 512
Cdd:COG4942   164 -ALRAELEAERAELEALLAELEEERAAlEALKAERQKLLARLEKELAELAAELAELQQE-AEELEALIARLEAEAAAAAE 241

                  .
gi 1213953156 513 R 513
Cdd:COG4942   242 R 242
PTZ00121 PTZ00121
MAEBL; Provisional
250-566 1.53e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  250 EAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQsLSEAMEALNREQESARLQQR----ERETLEEERQALTLRLEAEQQ 325
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADE-AKKAAEAKKKADEAKKAEEAkkadEAKKAEEAKKADEAKKAEEKK 1546
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  326 RCcvlQEERDAARAGQLSEHRELETLRAAlEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQL 405
Cdd:PTZ00121  1547 KA---DELKKAEELKKAEEKKKAEEAKKA-EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  406 ALVQ--SEVRRLEGELDTARRE--RDALQL----EMSLVQARYESQRIQLESELAVQL-----EQRVTERLAQAQESSLR 472
Cdd:PTZ00121  1623 EELKkaEEEKKKVEQLKKKEAEekKKAEELkkaeEENKIKAAEEAKKAEEDKKKAEEAkkaeeDEKKAAEALKKEAEEAK 1702
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  473 QAASLRehhRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDyELRLAREQARvcELQSGNQQLEEQRVELVER 552
Cdd:PTZ00121  1703 KAEELK---KKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKK--KIAHLKKEEEKKAEEIRKE 1776
                          330
                   ....*....|....
gi 1213953156  553 LQAMLQAHWDEANQ 566
Cdd:PTZ00121  1777 KEAVIEEELDEEDE 1790
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
330-553 1.92e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 51.98  E-value: 1.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  330 LQEERDAARAGQLSEHRELETLRAALEEERQTW--AQQEHQLKEHYQALQEESQAQL--EREKEKSQREAQAAWETQHQL 405
Cdd:PRK10929    32 LEQAKAAKTPAQAEIVEALQSALNWLEERKGSLerAKQYQQVIDNFPKLSAELRQQLnnERDEPRSVPPNMSTDALEQEI 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  406 ALVQSEV----RRLEGELDTARRERDALQLemsLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHH 481
Cdd:PRK10929   112 LQVSSQLleksRQAQQEQDRAREISDSLSQ---LPQQQTEARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESAALKAL 188
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1213953156  482 RKQLQ--DLSGQHQQElasqLAQFKVEMAEReeRQQQVaeDYELRLAREQarvceLQSGNQQLEEQRVELVERL 553
Cdd:PRK10929   189 VDELElaQLSANNRQE----LARLRSELAKK--RSQQL--DAYLQALRNQ-----LNSQRQREAERALESTELL 249
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
200-402 2.17e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  200 CERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVT 279
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  280 RLEQsLSEAMEALNREQEsaRLQQRERETLEEERQaLTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEER 359
Cdd:TIGR02169  393 KLEK-LKREINELKRELD--RLQEELQRLSEELAD-LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1213953156  360 qtwaQQEHQLKEHYQALQEEsQAQLEREKEKSQREAQAAWETQ 402
Cdd:TIGR02169  469 ----QELYDLKEEYDRVEKE-LSKLQRELAEAEAQARASEERV 506
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
375-567 2.61e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 375 ALQEESQAQLEREKEKSQREAQAA----WETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQAR---YESQRIQL 447
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELekelAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaeLEKEIAEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 448 ESELAvQLEQRVTERLAQAQESS--------LRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAE 519
Cdd:COG4942    96 RAELE-AQKEELAELLRALYRLGrqpplallLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1213953156 520 DYELRLAREQARVCELqsgnQQLEEQRVELVERLQAMLQAHWDEANQL 567
Cdd:COG4942   175 ELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAEL 218
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
190-569 3.44e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.94  E-value: 3.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  190 LDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKdtmieQLDKTLArvvegwnrhEAErtevLRGLQEEHQAAEL 269
Cdd:pfam01576   84 LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKL-----QLEKVTT---------EAK----IKKLEEDILLLED 145
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  270 TRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELE 349
Cdd:pfam01576  146 QNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIA 225
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  350 TLRAALEEERQTWAQQEHQLKEHYQALQEESQAQleREKEKSQREAQAawetqhQLALVQSEVRRLEGELDTARRERDAL 429
Cdd:pfam01576  226 ELQAQIAELRAQLAKKEEELQAALARLEEETAQK--NNALKKIRELEA------QISELQEDLESERAARNKAEKQRRDL 297
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  430 QLEMSLVQARYES--QRIQLESELAVQLEQRVTErLAQAQESSLRQaaslrehHRKQLQDLSGQHQQ---ELASQLAQFK 504
Cdd:pfam01576  298 GEELEALKTELEDtlDTTAAQQELRSKREQEVTE-LKKALEEETRS-------HEAQLQEMRQKHTQaleELTEQLEQAK 369
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  505 -----------------VEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAmLQAHWDEANQL 567
Cdd:pfam01576  370 rnkanlekakqalesenAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK-LQSELESVSSL 448

                   ..
gi 1213953156  568 LS 569
Cdd:pfam01576  449 LN 450
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
231-555 6.37e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 6.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 231 MIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQsLSEAMEALNREQESARLQQRERETLE 310
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEE-LEEELEELEAELEELREELEKLEKLL 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 311 EERQALTLRLEAEQQRccvlqeERDAARAGQLSEH-RELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKE 389
Cdd:COG4717   126 QLLPLYQELEALEAEL------AELPERLEELEERlEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE 199
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 390 KSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARY----ESQRIQLESELAVQLEQRVT----- 460
Cdd:COG4717   200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliAAALLALLGLGGSLLSLILTiagvl 279
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 461 ---ERLAQAQESSLRQAASLREHHRKQLQDLSGQ---HQQELASQLAQFKVEMAEREERQQQVAEDY-ELRLAREQARVC 533
Cdd:COG4717   280 flvLGLLALLFLLLAREKASLGKEAEELQALPALeelEEEELEELLAALGLPPDLSPEELLELLDRIeELQELLREAEEL 359
                         330       340
                  ....*....|....*....|..
gi 1213953156 534 ELQSGNQQLEEQRVELVERLQA 555
Cdd:COG4717   360 EEELQLEELEQEIAALLAEAGV 381
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
185-565 6.84e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.04  E-value: 6.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 185 GLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEgwnRHEAERTEVlRGLQEEH 264
Cdd:PRK02224  297 DLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE---RAEELREEA-AELESEL 372
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 265 QAAELTRSKQQETVTRLEQSLSEAMEALNreqesarlqqreretleeerqALTLRLEAEQQRCCVLQEERDAARAGQLSE 344
Cdd:PRK02224  373 EEAREAVEDRREEIEELEEEIEELRERFG---------------------DAPVDLGNAEDFLEELREERDELREREAEL 431
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 345 HRELETLRAALEEERQTWAQ-------QEHQLKEHYQALQE--ESQAQLEREKEKSqREAQAAWETQHQLAlvqSEVRRL 415
Cdd:PRK02224  432 EATLRTARERVEEAEALLEAgkcpecgQPVEGSPHVETIEEdrERVEELEAELEDL-EEEVEEVEERLERA---EDLVEA 507
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 416 EGELDTARRERDALQLEMSLVQARYESQRIQLES--ELAVQLEQRVTERLAQAQEssLRQAAslrEHHRKQLQDLSGQhQ 493
Cdd:PRK02224  508 EDRIERLEERREDLEELIAERRETIEEKRERAEElrERAAELEAEAEEKREAAAE--AEEEA---EEAREEVAELNSK-L 581
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1213953156 494 QELASQLaqfkvEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAmLQAHWDEAN 565
Cdd:PRK02224  582 AELKERI-----ESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRE-LEAEFDEAR 647
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
182-557 7.26e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 7.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  182 DFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVV--------EGWNRHEAER 253
Cdd:pfam02463  616 DEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEiqelqekaESELAKEEIL 695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  254 TEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQEsaRLQQRERETLEEERQALTLRLEAEQQRCCVLQEE 333
Cdd:pfam02463  696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELK--LLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKE 773
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  334 RDAA----RAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQ 409
Cdd:pfam02463  774 KELAeereKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  410 SEVRRLEGELdtarrerdaLQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKqlqdlS 489
Cdd:pfam02463  854 EELERLEEEI---------TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE-----I 919
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1213953156  490 GQHQQELASQLAQFKVEmaEREERQQQVAEDYELRLAREQARVcelqsgNQQLEEQRVELVERLQAML 557
Cdd:pfam02463  920 EERIKEEAEILLKYEEE--PEELLLEEADEKEKEENNKEEEEE------RNKRLLLAKEELGKVNLMA 979
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
196-455 7.28e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.74  E-value: 7.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 196 RRKHCERHIQSLQTRVLEL--QQQLAVAVAADRKKDTMIEQLDKTLARVvegwnRHEAERTEVLRGLQEEHQAAELTRSK 273
Cdd:pfam17380 346 RERELERIRQEERKRELERirQEEIAMEISRMRELERLQMERQQKNERV-----RQELEAARKVKILEEERQRKIQQQKV 420
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 274 QQETVtRLEQSLSEAMEALNREQESARLQQRERETLEEERQALT-LRLEAEQQRCCVLQ---EERDAARAGQLSE---HR 346
Cdd:pfam17380 421 EMEQI-RAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVErLRQQEEERKRKKLElekEKRDRKRAEEQRRkilEK 499
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 347 ELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEgeldtarrer 426
Cdd:pfam17380 500 ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLE---------- 569
                         250       260
                  ....*....|....*....|....*....
gi 1213953156 427 dALQLEMSLVQARYESQRIQLESELAVQL 455
Cdd:pfam17380 570 -AMEREREMMRQIVESEKARAEYEATTPI 597
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
382-569 9.18e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 9.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  382 AQLEREKEKSQREAQAAWETQHQLALVQSEVR----RLEGELDTARRERDAL----QLEMSLVQARYES---QRIQLESE 450
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRqqleRLRREREKAERYQALLkekrEYEGYELLKEKEAlerQKEAIERQ 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  451 LAvQLEQRVTERLAQAQESSLR--QAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMA-------EREERQQQVAE-- 519
Cdd:TIGR02169  246 LA-SLEEELEKLTEEISELEKRleEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAslersiaEKERELEDAEErl 324
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1213953156  520 -DYELRLAREQARVCELQsgnQQLEEQRVElVERLQAMLQAHWDEANQLLS 569
Cdd:TIGR02169  325 aKLEAEIDKLLAEIEELE---REIEEERKR-RDKLTEEYAELKEELEDLRA 371
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
190-556 1.10e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.40  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  190 LDSEHTRRKhCERHIQSLQTRVLELQQQLAVAVAADRKKDtmiEQLDKTLARVVEgwnrHEAERTEVLRGLQE-EHQAAE 268
Cdd:pfam01576  204 QELEKAKRK-LEGESTDLQEQIAELQAQIAELRAQLAKKE---EELQAALARLEE----ETAQKNNALKKIRElEAQISE 275
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  269 LTRSKQQETVTR-----LEQSLSEAMEALNREQESarlqqreretleeerqalTLRLEAEQQRccvLQEERDaaragqls 343
Cdd:pfam01576  276 LQEDLESERAARnkaekQRRDLGEELEALKTELED------------------TLDTTAAQQE---LRSKRE-------- 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  344 ehRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTAR 423
Cdd:pfam01576  327 --QEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSE 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  424 RERDALQLEMSLVQARY---ESQRIQLESELA-VQLE-QRVTERLAQAQESSLRQAASLREHHrKQLQDLSGQHQQE--- 495
Cdd:pfam01576  405 HKRKKLEGQLQELQARLsesERQRAELAEKLSkLQSElESVSSLLNEAEGKNIKLSKDVSSLE-SQLQDTQELLQEEtrq 483
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1213953156  496 ---LASQLAQFKvemAEREERQQQVAEDYELRLAREQarvcELQSGNQQLEEQRVELVERLQAM 556
Cdd:pfam01576  484 klnLSTRLRQLE---DERNSLQEQLEEEEEAKRNVER----QLSTLQAQLSDMKKKLEEDAGTL 540
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
255-530 1.13e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.57  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  255 EVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALnreQESARLQqreretleeeRQALTLRLEAEQQRCCVLQEER 334
Cdd:COG3096    836 AELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQL---QLLNKLL----------PQANLLADETLADRLEELREEL 902
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  335 DAARAGQ--LSEH----RELETLRAALeeerQTWAQQEHQLKEHYQAL---QEESQAQLEREKEKSQREAQAAWE-TQHQ 404
Cdd:COG3096    903 DAAQEAQafIQQHgkalAQLEPLVAVL----QSDPEQFEQLQADYLQAkeqQRRLKQQIFALSEVVQRRPHFSYEdAVGL 978
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  405 LALVQSEVRRLEGELDTARRERDALQLEMSLVQARYES---QRIQLES------ELAVQLEQRVTERLAQAQESSLRQAA 475
Cdd:COG3096    979 LGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQynqVLASLKSsrdakqQTLQELEQELEELGVQADAEAEERAR 1058
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1213953156  476 SlrehHRKQLQDLSGQHQQ---ELASQLAQFKVEMAEREERQQQVAEDYelRLAREQA 530
Cdd:COG3096   1059 I----RRDELHEELSQNRSrrsQLEKQLTRCEAEMDSLQKRLRKAERDY--KQEREQV 1110
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
237-559 1.13e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  237 KTLARVVEGWNRHEAERTEVLRGLQ-EEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQA 315
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELkLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  316 LTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTwAQQEHQLKEHYQALQEESQAQLER-EKEKSQRE 394
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE-LLKLERRKVDDEEKLKESEKEKKKaEKELKKEK 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  395 AQAAwETQHQLALVQ-SEVRRLEGELDTARRERDALQLEMSLV--QARYESQRIQLESELAVQLEQRVTE--------RL 463
Cdd:pfam02463  335 EEIE-ELEKELKELEiKREAEEEEEEELEKLQEKLEQLEEELLakKKLESERLSSAAKLKEEELELKSEEekeaqlllEL 413
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  464 AQAQESSLR----QAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRL-AREQARVCELQSG 538
Cdd:pfam02463  414 ARQLEDLLKeekkEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLvKLQEQLELLLSRQ 493
                          330       340
                   ....*....|....*....|.
gi 1213953156  539 NQQLEEQRVELVERLQAMLQA 559
Cdd:pfam02463  494 KLEERSQKESKARSGLKVLLA 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
260-473 1.21e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 1.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  260 LQEEHQAAEltrsKQQETVTRLEQsLSEAMEALNREQESARLQQReretleeerQALTLRLEAEQQRCCVLQEERDAARA 339
Cdd:COG4913    237 LERAHEALE----DAREQIELLEP-IRELAERYAAARERLAELEY---------LRAALRLWFAQRRLELLEAELEELRA 302
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  340 gqlsehrELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLER-EKEKSQREAQAAwETQHQLALVQSEVRRLEGE 418
Cdd:COG4913    303 -------ELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELE-ERERRRARLEALLAALGLP 374
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1213953156  419 LDTARRERDALQLEMSLVQARYESQRIQLESELAvqlEQRVTERLAQAQESSLRQ 473
Cdd:COG4913    375 LPASAEEFAALRAEAAALLEALEEELEALEEALA---EAEAALRDLRRELRELEA 426
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
197-560 1.26e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 1.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  197 RKHCERHIQSLQTRVLELQQQLA--VAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQ 274
Cdd:TIGR00618  306 EQQAQRIHTELQSKMRSRAKLLMkrAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQ 385
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  275 Q--ETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLR 352
Cdd:TIGR00618  386 QqkTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESA 465
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  353 AALEEERQTWAQQE---------HQLKEHYQALQEESQAQLEREKEKSQREAQAAWET----------QHQLALVQSEVR 413
Cdd:TIGR00618  466 QSLKEREQQLQTKEqihlqetrkKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPgpltrrmqrgEQTYAQLETSEE 545
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  414 RLEGELDTARRERDALQLEMSLVQ-------------------ARYESQRIQ----LESELAVQLEQRVTERLAQAQESS 470
Cdd:TIGR00618  546 DVYHQLTSERKQRASLKEQMQEIQqsfsiltqcdnrskedipnLQNITVRLQdlteKLSEAEDMLACEQHALLRKLQPEQ 625
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  471 LRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQvaedyELRLAREQARVCELQSGNQQLEEQRVELV 550
Cdd:TIGR00618  626 DLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP-----KELLASRQLALQKMQSEKEQLTYWKEMLA 700
                          410
                   ....*....|
gi 1213953156  551 ERLQAMLQAH 560
Cdd:TIGR00618  701 QCQTLLRELE 710
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
187-463 1.43e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 1.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 187 RDALDSEHTRRK---HCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARvvegwnrHEAERTEVLRGLQEE 263
Cdd:PRK02224  491 VEEVEERLERAEdlvEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAE-------LEAEAEEKREAAAEA 563
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 264 HQAAELTRSKQQETVTRLEQsLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDaaragqls 343
Cdd:PRK02224  564 EEEAEEAREEVAELNSKLAE-LKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE-------- 634
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 344 EHRELEtlrAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAawetqhqlalVQSEVRRLEgeldTAR 423
Cdd:PRK02224  635 RKRELE---AEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA----------VENELEELE----ELR 697
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1213953156 424 RERDALQLEMSLVQARYESQRiQLES---ELAVQLEQRVTERL 463
Cdd:PRK02224  698 ERREALENRVEALEALYDEAE-ELESmygDLRAELRQRNVETL 739
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
183-567 1.60e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  183 FQGLRDALDSEHTRRKhcerhIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVL----R 258
Cdd:COG4913    274 LEYLRAALRLWFAQRR-----LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLereiE 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  259 GLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCC----VLQEER 334
Cdd:COG4913    349 RLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRrelrELEAEI 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  335 DAARAGQLSEHRELETLRAAL----------------------EEER--------------------------------- 359
Cdd:COG4913    429 ASLERRKSNIPARLLALRDALaealgldeaelpfvgelievrpEEERwrgaiervlggfaltllvppehyaaalrwvnrl 508
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  360 ---------------------------------------QTWAQQEhqLKEHYQALQEESQAQLEREK------------ 388
Cdd:COG4913    509 hlrgrlvyervrtglpdperprldpdslagkldfkphpfRAWLEAE--LGRRFDYVCVDSPEELRRHPraitragqvkgn 586
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  389 ----EKSQREAQAA-----WETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYES-QRIQLESELAVQLEQ- 457
Cdd:COG4913    587 gtrhEKDDRRRIRSryvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlQRLAEYSWDEIDVASa 666
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  458 -----RVTERLAQAQESS--LRQAASLREHHRKQLQDLSGQhQQELASQLAQFKVEMAEREERQQQV---AEDYELRLAR 527
Cdd:COG4913    667 ereiaELEAELERLDASSddLAALEEQLEELEAELEELEEE-LDELKGEIGRLEKELEQAEEELDELqdrLEAAEDLARL 745
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 1213953156  528 EQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQL 567
Cdd:COG4913    746 ELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785
PTZ00121 PTZ00121
MAEBL; Provisional
261-552 1.84e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 1.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  261 QEEHQAAELTRSKQQETVTRLEQS---------------------------LSEAMEALNREQESARLQQRERETLEEER 313
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAAeekaeaaekkkeeakkkadaakkkaeeKKKADEAKKKAEEDKKKADELKKAAAAKK 1418
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  314 QALTLRLEAEQQRCC-----VLQEERDAARAGQLSEH-RELETLRAALEEERQTwaqQEHQLKEHYQALQEESQAQLERE 387
Cdd:PTZ00121  1419 KADEAKKKAEEKKKAdeakkKAEEAKKADEAKKKAEEaKKAEEAKKKAEEAKKA---DEAKKKAEEAKKADEAKKKAEEA 1495
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  388 KEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSlvQARYESQRIQLESELAVQLEQRVTERLAQAQ 467
Cdd:PTZ00121  1496 KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA--EEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  468 E---SSLRQAASLREHHRKQLQDLSGQHQQElasqlAQFKVEMAEREERQQQVAEdyELRLAREQARVCELQSGNQQLEE 544
Cdd:PTZ00121  1574 EdknMALRKAEEAKKAEEARIEEVMKLYEEE-----KKMKAEEAKKAEEAKIKAE--ELKKAEEEKKKVEQLKKKEAEEK 1646

                   ....*...
gi 1213953156  545 QRVELVER 552
Cdd:PTZ00121  1647 KKAEELKK 1654
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
377-559 2.58e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 2.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 377 QEESQAQLEREKEKSQREAQAAWEtqhQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLE 456
Cdd:COG3883    21 KQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 457 QRVT----ERLAQAQESS--LRQAASLR---EHHRKQLQDlsgqhQQELASQLAQFKVEMAEREERQQQVAEDYELRLAR 527
Cdd:COG3883    98 SGGSvsylDVLLGSESFSdfLDRLSALSkiaDADADLLEE-----LKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1213953156 528 EQARVCELQSGNQQLEEQRVELVERLQAMLQA 559
Cdd:COG3883   173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAE 204
PTZ00121 PTZ00121
MAEBL; Provisional
213-488 2.72e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  213 ELQQQLAVAVAADRKKdtmIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEAL 292
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKK---AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  293 NREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARagqlsEHRELETLRAALEEERqtwaQQEHQLKEh 372
Cdd:PTZ00121  1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE-----DKKKAEEAKKAEEDEK----KAAEALKK- 1696
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  373 yqalQEESQAQLEREKEKSQREAQAAWETQHqlalvQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELA 452
Cdd:PTZ00121  1697 ----EAEEAKKAEELKKKEAEEKKKAEELKK-----AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767
                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1213953156  453 VQLEQRVTERLAQAQESSLRQAASLREHHRKQLQDL 488
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
381-566 2.73e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 2.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 381 QAQLEREKEKSqREAQAAWE---TQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAV---- 453
Cdd:COG3206   181 EEQLPELRKEL-EEAEAALEefrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDAlpel 259
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 454 ---QLEQRVTERLAQAQESSLRQAASLREHH------RKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEdyelR 524
Cdd:COG3206   260 lqsPVIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQA----Q 335
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1213953156 525 LAREQARVCELQSGNQQLE--EQRVELVERLQAMLQAHWDEANQ 566
Cdd:COG3206   336 LAQLEARLAELPELEAELRrlEREVEVARELYESLLQRLEEARL 379
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
94-699 2.75e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 2.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156   94 KHIFEMESVRGQLQTMLQTSRDTaYRDPL------IPGAGSE----RREEDSFDSDStATLLNT--RPLQDLSPSSSAQA 161
Cdd:pfam15921  317 RQLSDLESTVSQLRSELREAKRM-YEDKIeelekqLVLANSElteaRTERDQFSQES-GNLDDQlqKLLADLHKREKELS 394
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  162 LEE-----LFPRYTSlrpgpplNPPDFQGLRDALDSEHTRRKHCERHIQSLQTrvlELQQQLAVAVAADRKKDTMIEQLD 236
Cdd:pfam15921  395 LEKeqnkrLWDRDTG-------NSITIDHLRRELDDRNMEVQRLEALLKAMKS---ECQGQMERQMAAIQGKNESLEKVS 464
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  237 KTLARVvegwnrheAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALnrEQESARLQQRERETLEEERQAL 316
Cdd:pfam15921  465 SLTAQL--------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAI--EATNAEITKLRSRVDLKLQELQ 534
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  317 TLRLEAEQQRCcvLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKehyqALQEEsQAQLEREKEKSQREAQ 396
Cdd:pfam15921  535 HLKNEGDHLRN--VQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAG----AMQVE-KAQLEKEINDRRLELQ 607
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  397 aawetqhqlalvqsEVRRLEGELDTARRERDA----LQLE-MSLVQAryESQRIQLESELAVQLEQRVTErlAQAQESSL 471
Cdd:pfam15921  608 --------------EFKILKDKKDAKIRELEArvsdLELEkVKLVNA--GSERLRAVKDIKQERDQLLNE--VKTSRNEL 669
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  472 RQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQ-------------QVAEDYELRLAREQARVCELQSG 538
Cdd:pfam15921  670 NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNtlksmegsdghamKVAMGMQKQITAKRGQIDALQSK 749
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  539 NQQLEEQRVElVERLQAMLQAHWDEANQLLSTTlpPPNPPAPPAGPSSPGPQEPEKEERrvwtMPPMAVALKPVLQQSRE 618
Cdd:pfam15921  750 IQFLEEAMTN-ANKEKHFLKEEKNKLSQELSTV--ATEKNKMAGELEVLRSQERRLKEK----VANMEVALDKASLQFAE 822
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  619 ARD----ELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKP---DLTSSTAGAFSALGAFHPDHRAERPFPEEDPGP 691
Cdd:pfam15921  823 CQDiiqrQEQESVRLKLQHTLDVKELQGPGYTSNSSMKPRLLQPasfTRTHSNVPSSQSTASFLSHHSRKTNALKEDPTR 902

                   ....*...
gi 1213953156  692 DGEGLLKQ 699
Cdd:pfam15921  903 DLKQLLQE 910
mukB PRK04863
chromosome partition protein MukB;
205-415 3.38e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.03  E-value: 3.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  205 QSLQTRVLELQQQLAVAVAADRKkdtmIEQLDKTLARVVEGWNRHEAERT--EVLRGLQEE-HQAAELTRSKQQetVTRL 281
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQ----FEQAYQLVRKIAGEVSRSEAWDVarELLRRLREQrHLAEQLQQLRMR--LSEL 525
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  282 EQSLSEAMEAlNREQESARLQQRERETLEEERQALTLRLEAEQQRccvLQEERDAARAGQLSEHRELETLRAALEEERQT 361
Cdd:PRK04863   526 EQRLRQQQRA-ERLLAEFCKRLGKNLDDEDELEQLQEELEARLES---LSESVSEARERRMALRQQLEQLQARIQRLAAR 601
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1213953156  362 wAQQEHQLKEHYQALQEES--------------QAQLEREKEKSQREAQAAWETQHqlalVQSEVRRL 415
Cdd:PRK04863   602 -APAWLAAQDALARLREQSgeefedsqdvteymQQLLERERELTVERDELAARKQA----LDEEIERL 664
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
213-444 4.33e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 4.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 213 ELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAErtevLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEAL 292
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 293 NREQESARlQQRERETLEEERQALTLRLEAEQqrccVLQEERDAARAGQLSEHR--ELETLRAALEEERQTWAQQEHQLK 370
Cdd:COG4942   100 EAQKEELA-ELLRALYRLGRQPPLALLLSPED----FLDAVRRLQYLKYLAPARreQAEELRADLAELAALRAELEAERA 174
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1213953156 371 EHYQALQEESQAQLEREKEKSQREAqaawetqhQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQR 444
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQK--------LLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
344-568 5.18e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 5.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  344 EHRELETLRAALEEERQTWAQQEHQLKEHYQALQ----------EESQAQLEREKEksqREAQAAWETQHQLALVQSEVR 413
Cdd:COG3096    844 RRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNkllpqanllaDETLADRLEELR---EELDAAQEAQAFIQQHGKALA 920
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  414 RLEGELDTARR---ERDALQLEMSLVQARYESQRIQLESelAVQLEQRVT--------ERLAQAQESS------LRQAAS 476
Cdd:COG3096    921 QLEPLVAVLQSdpeQFEQLQADYLQAKEQQRRLKQQIFA--LSEVVQRRPhfsyedavGLLGENSDLNeklrarLEQAEE 998
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  477 LREHHRKQLQDLSGQHQ---QELAS----------QLAQFKVEMAEREERQQQVAEdyelrlAREQARVCELQSGNQQLE 543
Cdd:COG3096    999 ARREAREQLRQAQAQYSqynQVLASlkssrdakqqTLQELEQELEELGVQADAEAE------ERARIRRDELHEELSQNR 1072
                          250       260
                   ....*....|....*....|....*
gi 1213953156  544 EQRVELvERLQAMLQAHWDEANQLL 568
Cdd:COG3096   1073 SRRSQL-EKQLTRCEAEMDSLQKRL 1096
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
186-519 5.69e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 5.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  186 LRDALDSEHTRRKH-CERHIQSLQTRVLELQQQLAvavaadrKKDTMIEQLDKTLARVVEgwnRHEAERTEVLRGLQEEH 264
Cdd:TIGR02169  220 KREYEGYELLKEKEaLERQKEAIERQLASLEEELE-------KLTEEISELEKRLEEIEQ---LLEELNKKIKDLGEEEQ 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  265 QAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAgqlse 344
Cdd:TIGR02169  290 LRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----- 364
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  345 hrELETLRAALEEERqtwaqqehqlKEHYQALQEESQAQLEREKEKSQREaqaawETQHQLALVQSEVRRLEGELdtarr 424
Cdd:TIGR02169  365 --ELEDLRAELEEVD----------KEFAETRDELKDYREKLEKLKREIN-----ELKRELDRLQEELQRLSEEL----- 422
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  425 erdaLQLEMSLvqARYESQRIQLESEL-AVQLEQRvterlaqAQESSLRQAASLREHHRKQLQDLSgQHQQELASQLAQF 503
Cdd:TIGR02169  423 ----ADLNAAI--AGIEAKINELEEEKeDKALEIK-------KQEWKLEQLAADLSKYEQELYDLK-EEYDRVEKELSKL 488
                          330
                   ....*....|....*.
gi 1213953156  504 KVEMAEREERQQQVAE 519
Cdd:TIGR02169  489 QRELAEAEAQARASEE 504
mukB PRK04863
chromosome partition protein MukB;
201-557 5.97e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 5.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  201 ERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARV--VEGWNRHEAERTEVLRGLQEEHQAAEltrSKQQETV 278
Cdd:PRK04863   382 EARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALerAKQLCGLPDLTADNAEDWLEEFQAKE---QEATEEL 458
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  279 TRLEQSLSEAMEALNREQESARLQQreretleeerqaltlRLEAEQQRccvlQEERDAARagqlsehrelETLRAAleEE 358
Cdd:PRK04863   459 LSLEQKLSVAQAAHSQFEQAYQLVR---------------KIAGEVSR----SEAWDVAR----------ELLRRL--RE 507
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  359 RQTWAQQEHQLKEHYQALQEESQAQleREKEKSQREAQAAWETQHQLAlvqSEVRRLEGELDTarrERDALQLEMSLVQA 438
Cdd:PRK04863   508 QRHLAEQLQQLRMRLSELEQRLRQQ--QRAERLLAEFCKRLGKNLDDE---DELEQLQEELEA---RLESLSESVSEARE 579
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  439 RYESQRIQLEselavQLEQRVTERLAQAQESSLRQAASlrehhrKQLQDLSGQHqQELASQLAQFKVEMAEREERQQQVA 518
Cdd:PRK04863   580 RRMALRQQLE-----QLQARIQRLAARAPAWLAAQDAL------ARLREQSGEE-FEDSQDVTEYMQQLLERERELTVER 647
                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1213953156  519 EDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAML 557
Cdd:PRK04863   648 DELAARKQALDEEIERLSQPGGSEDPRLNALAERFGGVL 686
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
402-563 6.20e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 6.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 402 QHQLALVQSEVRRLEGELDTARRERDALQLEmsLVQARYESQRIQLESELAVQLEQRVTERLAQAqeSSLRQAASLR--- 478
Cdd:COG1579    23 EHRLKELPAELAELEDELAALEARLEAAKTE--LEDLEKEIKRLELEIEEVEARIKKYEEQLGNV--RNNKEYEALQkei 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 479 EHHRKQLQDLSgQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQ 558
Cdd:COG1579    99 ESLKRRISDLE-DEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPELL 177

                  ....*
gi 1213953156 559 AHWDE 563
Cdd:COG1579   178 ALYER 182
PTZ00121 PTZ00121
MAEBL; Provisional
188-546 9.58e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 9.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  188 DALDSEHTRRKHCERHIQSlqTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAA 267
Cdd:PTZ00121  1138 DARKAEEARKAEDAKRVEI--ARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAE 1215
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  268 ELTR---SKQQETVTRLEQSLSEAMEALNREQ----------ESARLQQRERETLEEERQ----ALTLRlEAEqqrccvl 330
Cdd:PTZ00121  1216 EARKaedAKKAEAVKKAEEAKKDAEEAKKAEEernneeirkfEEARMAHFARRQAAIKAEearkADELK-KAE------- 1287
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  331 qEERDAARAGQLSEHRELETLRAALEEERQTwaqqehqlkehyqalqEESQAQLEREKEKSQREAQAAWETQHQLALVQS 410
Cdd:PTZ00121  1288 -EKKKADEAKKAEEKKKADEAKKKAEEAKKA----------------DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA 1350
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  411 EVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLEselavqlEQRVTERLAQAQESSLRQAASLR--EHHRKQLQDL 488
Cdd:PTZ00121  1351 EAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE-------EKKKADEAKKKAEEDKKKADELKkaAAAKKKADEA 1423
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1213953156  489 SGQHQQELASQLAQFKVEMAEREERQQQVAEDY----ELRLAREQARVCElqSGNQQLEEQR 546
Cdd:PTZ00121  1424 KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkaeEAKKKAEEAKKAD--EAKKKAEEAK 1483
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
260-541 9.97e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.20  E-value: 9.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  260 LQEEHQAAELTRSKQQE---------TVTRLEQSLSEAMEALNreqESARLQQRERETLEEERQALTLRLEAEQQRCCVL 330
Cdd:PRK10929   112 LQVSSQLLEKSRQAQQEqdrareisdSLSQLPQQQTEARRQLN---EIERRLQTLGTPNTPLAQAQLTALQAESAALKAL 188
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  331 QEERDAAragQLSEH--RELETLRAALEEERQtwaqqeHQLKEHYQALQEESQAQlerekekSQREAQAAWETQHQLAlv 408
Cdd:PRK10929   189 VDELELA---QLSANnrQELARLRSELAKKRS------QQLDAYLQALRNQLNSQ-------RQREAERALESTELLA-- 250
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  409 qsevrrlEGELDTARRERDALQLEMSLVQA-RYESQRIQLeseLAVQleqrvtERLAQAQESSLRQAAS-LREHH----- 481
Cdd:PRK10929   251 -------EQSGDLPKSIVAQFKINRELSQAlNQQAQRMDL---IASQ------QRQAASQTLQVRQALNtLREQSqwlgv 314
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1213953156  482 --------RKQLQDLSGQHQ-QELASQLAQFKV------EMAEREERQQQVAEDYELRLAREQARVCELQSGNQQ 541
Cdd:PRK10929   315 snalgealRAQVARLPEMPKpQQLDTEMAQLRVqrlryeDLLNKQPQLRQIRQADGQPLTAEQNRILDAQLRTQR 389
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
186-514 1.04e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.37  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  186 LRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAAdrkkdtmIEQLDKTLARVVegwNRHEAERTEVLRGLQEEHQ 265
Cdd:pfam12128  609 AEEALQSAREKQAAAEEQLVQANGELEKASREETFARTA-------LKNARLDLRRLF---DEKQSEKDKKNKALAERKD 678
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  266 AAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETL---------EEERQALTLRLEAEQQRCCVLQEERDA 336
Cdd:pfam12128  679 SANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVvegaldaqlALLKAAIAARRSGAKAELKALETWYKR 758
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  337 ARAGQ-------LSEHRELETLRAALEEErqtwAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQ 409
Cdd:pfam12128  759 DLASLgvdpdviAKLKREIRTLERKIERI----AVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLI 834
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  410 SEVRRLEGELDTARRERDALQLEMS--LVQARYESQRIQL--ESELAVQLEQRVTERLAQAQEsSLRQAASLREHHRKQL 485
Cdd:pfam12128  835 ADTKLRRAKLEMERKASEKQQVRLSenLRGLRCEMSKLATlkEDANSEQAQGSIGERLAQLED-LKLKRDYLSESVKKYV 913
                          330       340
                   ....*....|....*....|....*....
gi 1213953156  486 QDLSGQHQQELASQLAQFKVEMAEREERQ 514
Cdd:pfam12128  914 EHFKNVIADHSGSGLAETWESLREEDHYQ 942
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
182-476 1.10e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 182 DFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQ 261
Cdd:COG4717   200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVL 279
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 262 ------EEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERD 335
Cdd:COG4717   280 flvlglLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 336 AARAGQLSEHRELETLRAALE-------EERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQhqLALV 408
Cdd:COG4717   360 EEELQLEELEQEIAALLAEAGvedeeelRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE--LEEL 437
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 409 QSEVRRLEGELDTARRERDALQLEMSLV---------QARYESQRIQLESE--------LAVQLEQRVTERLAQAQESSL 471
Cdd:COG4717   438 EEELEELEEELEELREELAELEAELEQLeedgelaelLQELEELKAELRELaeewaalkLALELLEEAREEYREERLPPV 517

                  ....*
gi 1213953156 472 RQAAS 476
Cdd:COG4717   518 LERAS 522
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
207-439 1.57e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  207 LQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEhqaaeltrSKQQETVTRLEQSLS 286
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEE--------RKRRDKLTEEYAELK 363
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  287 EAMEALNREQESarlqqreretLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQE 366
Cdd:TIGR02169  364 EELEDLRAELEE----------VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE 433
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1213953156  367 HQLKEhYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQAR 439
Cdd:TIGR02169  434 AKINE-LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
PTZ00121 PTZ00121
MAEBL; Provisional
193-429 1.62e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  193 EHTRRKHCERHIQSLqtRVLELQQQLAVAVAADRKKDTMIEQLDKTlarvvegwnRHEAERTEVLRGLQEEHQAAELTRS 272
Cdd:PTZ00121  1572 AEEDKNMALRKAEEA--KKAEEARIEEVMKLYEEEKKMKAEEAKKA---------EEAKIKAEELKKAEEEKKKVEQLKK 1640
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  273 KQQETVTRLEQSLSEamealnREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAaragqlSEHRELETLR 352
Cdd:PTZ00121  1641 KEAEEKKKAEELKKA------EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA------EEAKKAEELK 1708
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1213953156  353 AALEEERQTwAQQEHQLKEHYQALQEesqaQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDAL 429
Cdd:PTZ00121  1709 KKEAEEKKK-AEELKKAEEENKIKAE----EAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
378-567 2.18e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  378 EESQAQLEREKEKSQREAQaawetqhqLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLeSELAVQLEQ 457
Cdd:TIGR02168  667 KTNSSILERRREIEELEEK--------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI-SALRKDLAR 737
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  458 rvterlAQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVaEDYELRLAREQARVCELQS 537
Cdd:TIGR02168  738 ------LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI-EQLKEELKALREALDELRA 810
                          170       180       190
                   ....*....|....*....|....*....|
gi 1213953156  538 GNQQLEEQRVELVERLQAMLQAHWDEANQL 567
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRL 840
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
314-570 2.76e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 2.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  314 QALTLRLEAEQQrccVLQEERDAARAGQLSEHRELETLRAALEEERQT--WAQQEHQLKEHYQALQEESQAQLEREKEKS 391
Cdd:TIGR00618  197 ELLTLRSQLLTL---CTPCMPDTYHERKQVLEKELKHLREALQQTQQShaYLTQKREAQEEQLKKQQLLKQLRARIEELR 273
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  392 QREA-------------QAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQR 458
Cdd:TIGR00618  274 AQEAvleetqerinrarKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQ 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  459 VTERLAQAQESSLR-----QAASLREHHRKQLQDLSGQHQQE--LASQLAQFKVEMA--------EREERQQQVAEDYEL 523
Cdd:TIGR00618  354 EIHIRDAHEVATSIreiscQQHTLTQHIHTLQQQKTTLTQKLqsLCKELDILQREQAtidtrtsaFRDLQGQLAHAKKQQ 433
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1213953156  524 RLAREQARVCELQSGNQQLEEQrveLVERLQAMLQAHWDEANQLLST 570
Cdd:TIGR00618  434 ELQQRYAELCAAAITCTAQCEK---LEKIHLQESAQSLKEREQQLQT 477
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
250-549 3.08e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 44.79  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  250 EAERTEVLRGLQ----EEHQAAELTRSKQQET--VTRLEqslsEAMEALNREQESARLQQRERETLEEERQALTLRLEAE 323
Cdd:PRK10246   215 PEQVQSLTASLQvltdEEKQLLTAQQQQQQSLnwLTRLD----ELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPAR 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  324 QQRCCVL-QEERDAARAGQLSEHRELET-LRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWET 401
Cdd:PRK10246   291 QLRPHWErIQEQSAALAHTRQQIEEVNTrLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNELAGWRA 370
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  402 Q-HQLALVQSEVRRLEGELDTARRERDAL-QLEMSLVqaryesqriqlESELAVQLEQRVTERLAQAQESSLRQAASLRE 479
Cdd:PRK10246   371 QfSQQTSDREQLRQWQQQLTHAEQKLNALpAITLTLT-----------ADEVAAALAQHAEQRPLRQRLVALHGQIVPQQ 439
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  480 HHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAedyelrlarEQARVCELQSGNQQLEEQRVEL 549
Cdd:PRK10246   440 KRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLA---------DVKTICEQEARIKDLEAQRAQL 500
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
186-571 3.14e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  186 LRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAvavaadrKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRglQEEHQ 265
Cdd:TIGR00618  443 CAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQ-------TKEQIHLQETRKKAVVLARLLELQEEPCPLCG--SCIHP 513
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  266 AAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEH 345
Cdd:TIGR00618  514 NPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT 593
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  346 RELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLErEKEKSQREAQA-AWETQHQLALVQSEVR------RLEGE 418
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLH-LQQCSQELALKlTALHALQLTLTQERVRehalsiRVLPK 672
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  419 LDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAAslrehhrkQLQDLSGQ---HQQE 495
Cdd:TIGR00618  673 ELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSS--------LGSDLAARedaLNQS 744
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156  496 LASQLAQFKVEMAEREERQQQVAEDY---ELRLAREQARVCELQSGNQQLEEqRVELVERLQAMLQAHWDEANQLLSTT 571
Cdd:TIGR00618  745 LKELMHQARTVLKARTEAHFNNNEEVtaaLQTGAELSHLAAEIQFFNRLREE-DTHLLKTLEAEIGQEIPSDEDILNLQ 822
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
201-398 3.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 3.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 201 ERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLArvvegwnRHEAERTEVLRGLQEEHQAAELTRSKQQETVTR 280
Cdd:COG4942    61 ERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE-------AQKEELAELLRALYRLGRQPPLALLLSPEDFLD 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 281 LEQSLsEAMEALNREQESarlQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 360
Cdd:COG4942   134 AVRRL-QYLKYLAPARRE---QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELA 209
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1213953156 361 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAA 398
Cdd:COG4942   210 ELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
201-461 3.28e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  201 ERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQ-------LDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSK 273
Cdd:COG3096    835 EAELAALRQRRSELERELAQHRAQEQQLRQQLDQlkeqlqlLNKLLPQANLLADETLADRLEELREELDAAQEAQAFIQQ 914
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  274 QQETVTRLEQSLSeameALNREQES-ARLQQreretleeERQALTLRLEAEQQRCCVLQE--ERDAA-----RAGQLSEH 345
Cdd:COG3096    915 HGKALAQLEPLVA----VLQSDPEQfEQLQA--------DYLQAKEQQRRLKQQIFALSEvvQRRPHfsyedAVGLLGEN 982
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  346 REL-ETLRAALEEERQTWAQQEHQLKehyQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARR 424
Cdd:COG3096    983 SDLnEKLRARLEQAEEARREAREQLR---QAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERARI 1059
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1213953156  425 ERDALQLEMSLVQAR---YESQRIQLESELAvQLEQRVTE 461
Cdd:COG3096   1060 RRDELHEELSQNRSRrsqLEKQLTRCEAEMD-SLQKRLRK 1098
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
404-532 5.70e-04

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 43.30  E-value: 5.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 404 QLALVQSEVRRLEGELDTARRERDALQ-------------LEMSLVqARYESQRIQLESELAvQLEQRVTE---RLAQAQ 467
Cdd:COG3524   178 AVRFAEEEVERAEERLRDAREALLAFRnrngildpeataeALLQLI-ATLEGQLAELEAELA-ALRSYLSPnspQVRQLR 255
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1213953156 468 esslRQAASLREHHRKQLQDLSGQHQQE-LASQLAQFKVEMAEREERQQQvaedYELRLAR-EQARV 532
Cdd:COG3524   256 ----RRIAALEKQIAAERARLTGASGGDsLASLLAEYERLELEREFAEKA----YTSALAAlEQARI 314
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
242-398 6.65e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.87  E-value: 6.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 242 VVEGWNRHE-----AERTEVLRGLQEEHQAAELtRSKQQETVTRLEQslseamealnREQESARLQQRERETLEEERQAL 316
Cdd:PRK09510   60 VVEQYNRQQqqqksAKRAEEQRKKKEQQQAEEL-QQKQAAEQERLKQ----------LEKERLAAQEQKKQAEEAAKQAA 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 317 TLRLEAEQQRccvlQEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQA---LQEESQAQLERE-KEKSQ 392
Cdd:PRK09510  129 LKQKQAEEAA----AKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAkkkAEAEAAAKAAAEaKKKAE 204

                  ....*.
gi 1213953156 393 REAQAA 398
Cdd:PRK09510  205 AEAKKK 210
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
330-467 9.77e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 42.05  E-value: 9.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 330 LQEERDAARAGQLSEHRELETLRAALEEerqtwaqqehqLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQ 409
Cdd:pfam09787  52 LRQERDLLREEIQKLRGQIQQLRTELQE-----------LEAQQQEEAESSREQLQELEEQLATERSARREAEAELERLQ 120
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1213953156 410 SEVRRLEGELdtaRRERDALQLEMSLVQARYESQRIQL---------ESELAVQLEQrVTERLAQAQ 467
Cdd:pfam09787 121 EELRYLEEEL---RRSKATLQSRIKDREAEIEKLRNQLtsksqssssQSELENRLHQ-LTETLIQKQ 183
PTZ00121 PTZ00121
MAEBL; Provisional
193-546 1.16e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  193 EHTRRKHCERHIQSLQtRVLELQQQLAVAVAADRKKDT-----MIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAA 267
Cdd:PTZ00121  1215 EEARKAEDAKKAEAVK-KAEEAKKDAEEAKKAEEERNNeeirkFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD 1293
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  268 ELTRSKQQETVTRLEQSLSEAMEA--LNREQESARlqqreretleeeRQALTLRLEAEqqrccvlqEERDAARAGQLSEH 345
Cdd:PTZ00121  1294 EAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAK------------KKADAAKKKAE--------EAKKAAEAAKAEAE 1353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  346 RELETLRAALEEERQTWAQQEhqlkehyqalQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGEldtaRRE 425
Cdd:PTZ00121  1354 AAADEAEAAEEKAEAAEKKKE----------EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA----KKK 1419
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  426 RDALQLEMSLVQARYESQRIQLESELAVQLEQRVTErlAQAQESSLRQAASLR--EHHRKQLQDLSGQHQQELASQLAQF 503
Cdd:PTZ00121  1420 ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE--AKKAEEAKKKAEEAKkaDEAKKKAEEAKKADEAKKKAEEAKK 1497
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1213953156  504 KVEMAEREERQQQVAEdyELRLAREQARVCELQSGnqqlEEQR 546
Cdd:PTZ00121  1498 KADEAKKAAEAKKKAD--EAKKAEEAKKADEAKKA----EEAK 1534
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
221-556 1.22e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  221 AVAADRKKDTMIEQLDKTLARVVEgwNRHEAERTEvlRGLQEEHQaaELTRSKqqETVTRLEQSLSEAMEALNREQESAR 300
Cdd:pfam01576  627 AEAEAREKETRALSLARALEEALE--AKEELERTN--KQLRAEME--DLVSSK--DDVGKNVHELERSKRALEQQVEEMK 698
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  301 LQQRERETLEEERQALTLRLEAEQQRCCVlQEERD-AARAGQLSEHReletlRAALEEERQTWAQQEHQLKEHYQALQEE 379
Cdd:pfam01576  699 TQLEELEDELQATEDAKLRLEVNMQALKA-QFERDlQARDEQGEEKR-----RQLVKQVRELEAELEDERKQRAQAVAAK 772
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  380 SQAQLEREKEKSQREA--QAAWETQHQLALVQSEVRRLEGELDTARRERDALqlemsLVQAR--------YESQRIQLES 449
Cdd:pfam01576  773 KKLELDLKELEAQIDAanKGREEAVKQLKKLQAQMKDLQRELEEARASRDEI-----LAQSKesekklknLEAELLQLQE 847
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  450 ELAV---QLEQRVTER--LAQAQESSLRQAASLREHHRkQLQDLSGQHQQELASQlaQFKVEM-AEREERQQQVAEDYEL 523
Cdd:pfam01576  848 DLAAserARRQAQQERdeLADEIASGASGKSALQDEKR-RLEARIAQLEEELEEE--QSNTELlNDRLRKSTLQVEQLTT 924
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1213953156  524 RLAREQARVCELQSGNQQLEEQRVELVERLQAM 556
Cdd:pfam01576  925 ELAAERSTSQKSESARQQLERQNKELKAKLQEM 957
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
392-559 1.35e-03

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 42.27  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 392 QREAQAAWetQHQLALVQSEVR-RLEGELDTARRER---DALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAq 467
Cdd:pfam04632 158 RARLRARL--RDALRLAAAALAgAPGAEAFEAARLRlaaDILALEALRSHAAFESPRGRARARALRRLLARMLALLPRL- 234
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 468 eSSLRQaaslrehHRKQLQDLSGQHQQELASQLAqfkvEMAEREERQQqvAEDYELRLAREQARVCELQSGNQQLEEQRV 547
Cdd:pfam04632 235 -RSLAR-------LLARLRTEGAGTVPELAALLD----ELAAWEAALA--AEALQAALAALRARLRALRPALPLDFDTAA 300
                         170
                  ....*....|..
gi 1213953156 548 ELVERLQAMLQA 559
Cdd:pfam04632 301 ELLARLADLLAE 312
PspA COG1842
Phage shock protein A [Transcription, Signal transduction mechanisms];
330-507 1.46e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];


Pssm-ID: 441447 [Multi-domain]  Cd Length: 217  Bit Score: 40.96  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 330 LQEERDAArAGQLSEHRELETLRAALEEERQTWAQQEHQLKEH------YQALQEESQAQLEREKEKSQREAQAAwetqh 403
Cdd:COG1842    39 LVEARQAL-AQVIANQKRLERQLEELEAEAEKWEEKARLALEKgredlaREALERKAELEAQAEALEAQLAQLEE----- 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 404 QLALVQSEVRRLEGELDTARRERDALQlemslvqARYESQRIQ---------LESELAV----QLEQRVTERLAQAQESS 470
Cdd:COG1842   113 QVEKLKEALRQLESKLEELKAKKDTLK-------ARAKAAKAQekvnealsgIDSDDATsaleRMEEKIEEMEARAEAAA 185
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1213953156 471 -LRQAASLREhhrkQLQDLSGQHqqELASQLAQFKVEM 507
Cdd:COG1842   186 eLAAGDSLDD----ELAELEADS--EVEDELAALKAKM 217
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
196-488 1.74e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  196 RRKHCERHIQSLQTRVLELQQQLAvavAADRKKDTMIEQLD--KTLARVVEGWNRHEAERTEvLRGLQEEHQAAELTRS- 272
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLE---ALEAELDALQERREalQRLAEYSWDEIDVASAERE-IAELEAELERLDASSDd 686
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  273 --KQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELET 350
Cdd:COG4913    687 laALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  351 LRAALEEERQTWAQQEHQL-----------KEHYQALQEESQAQLER-----------------EKEKSQREAQAAWETQ 402
Cdd:COG4913    767 LRENLEERIDALRARLNRAeeeleramrafNREWPAETADLDADLESlpeylalldrleedglpEYEERFKELLNENSIE 846
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  403 HQLALVQsevrRLEGELDTARRERDalQLEMSLVQARYESQR-IQLE-SELAVQLEQRVTERLAQAQESSLRQAASLREH 480
Cdd:COG4913    847 FVADLLS----KLRRAIREIKERID--PLNDSLKRIPFGPGRyLRLEaRPRPDPEVREFRQELRAVTSGASLFDEELSEA 920

                   ....*...
gi 1213953156  481 HRKQLQDL 488
Cdd:COG4913    921 RFAALKRL 928
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
188-570 1.83e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 42.05  E-value: 1.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 188 DALDSEHTRRkhCERHIQSLQTRVLELQQQLAvavAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAA 267
Cdd:pfam07111 294 DSLEPEFPKK--CRSLLNRWREKVFALMVQLK---AQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEV 368
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 268 ELTRSkqqeTVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCcvlqeERDAARAGQLSEH-- 345
Cdd:pfam07111 369 EVERM----SAKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRV-----EQAVARIPSLSNRls 439
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 346 ---RELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAwETQHQLALVQSEVRRL--EGELD 420
Cdd:pfam07111 440 yavRKVHTIKGLMARKVALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDA-ELQLSAHLIQQEVGRAreQGEAE 518
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 421 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQaaslREHHRKQLQDLSGQHQQELASQL 500
Cdd:pfam07111 519 RQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQ----QEIYGQALQEKVAEVETRLREQL 594
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1213953156 501 AQFKVEMAEREERQQQVAedyeLRLAREQARVCELQSGNQQL----EEQRVELVERLQAMLQAHWDEANQLLST 570
Cdd:pfam07111 595 SDTKRRLNEARREQAKAV----VSLRQIQHRATQEKERNQELrrlqDEARKEEGQRLARRVQELERDKNLMLAT 664
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
200-406 2.11e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  200 CERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEH---QAAELTRSKQQE 276
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEaelEELESRLEELEE 379
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  277 TVTRLEQ---SLSEAMEALNREQESARLQ----QRERETLEEERQALTLRL-EAEQQRCCVLQEERDAARAGQLSEHREL 348
Cdd:TIGR02168  380 QLETLRSkvaQLELQIASLNNEIERLEARlerlEDRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELERL 459
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  349 ETLRAALEEERQTWAQQEHQLKEHYQALQE--ESQAQLEREKEKSQREAQAAWETQHQLA 406
Cdd:TIGR02168  460 EEALEELREELEEAEQALDAAERELAQLQArlDSLERLQENLEGFSEGVKALLKNQSGLS 519
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
186-513 2.88e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.49  E-value: 2.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  186 LRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAvAVAADRKKDTMIEQLdktlarvVEGWNRHEAERTEVLRGLQEEHQ 265
Cdd:TIGR00618  547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDN-RSKEDIPNLQNITVR-------LQDLTEKLSEAEDMLACEQHALL 618
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  266 -AAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSE 344
Cdd:TIGR00618  619 rKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEM 698
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  345 HRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQR-EAQAAWETQHQ-----------LALVQ--S 410
Cdd:TIGR00618  699 LAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKElMHQARTVLKARteahfnnneevTAALQtgA 778
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  411 EVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERlAQAQESSLRQAASLREHHRKQLQDLSG 490
Cdd:TIGR00618  779 ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEE-EQFLSRLEEKSATLGEITHQLLKYEEC 857
                          330       340
                   ....*....|....*....|...
gi 1213953156  491 QHQQElasQLAQFKVEMAEREER 513
Cdd:TIGR00618  858 SKQLA---QLTQEQAKIIQLSDK 877
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
205-466 2.94e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 2.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  205 QSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKtLARVVEGWNRHEAERTEVLRGLQEEHQAaeltrskqqETVTRLEQS 284
Cdd:COG3096    451 QQATEEVLELEQKLSVADAARRQFEKAYELVCK-IAGEVERSQAWQTARELLRRYRSQQALA---------QRLQQLRAQ 520
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  285 LSEAMEALNREQESARLQQreretleeerqaltlrleaeqqRCCVLQeerdaarAGQLSEHRELETLRAALEEERQTWAQ 364
Cdd:COG3096    521 LAELEQRLRQQQNAERLLE----------------------EFCQRI-------GQQLDAAEELEELLAELEAQLEELEE 571
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156  365 QEHQLKEHYQALQEESQAQLEREKEKSQREaqAAWETqhqlalVQSEVRRLEGELDTARRERDALQLEMSlVQARYESQR 444
Cdd:COG3096    572 QAAEAVEQRSELRQQLEQLRARIKELAARA--PAWLA------AQDALERLREQSGEALADSQEVTAAMQ-QLLEREREA 642
                          250       260
                   ....*....|....*....|....
gi 1213953156  445 IQLESELAVQLEQ--RVTERLAQA 466
Cdd:COG3096    643 TVERDELAARKQAleSQIERLSQP 666
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
366-531 2.98e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 2.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 366 EHQLKEHYQALQEesqaqLEREKEKSQREAQAAwetQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRI 445
Cdd:COG1579    23 EHRLKELPAELAE-----LEDELAALEARLEAA---KTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEAL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 446 QLESELAvqleqrvtERLAQAQESSLRQAASLREHHRKQLQDLsgqhQQELASQLAQFKVEMAEREERQQQVAEDYE-LR 524
Cdd:COG1579    95 QKEIESL--------KRRISDLEDEILELMERIEELEEELAEL----EAELAELEAELEEKKAELDEELAELEAELEeLE 162

                  ....*..
gi 1213953156 525 LAREQAR 531
Cdd:COG1579   163 AEREELA 169
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
352-465 3.29e-03

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 38.39  E-value: 3.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 352 RAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKE---KSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDA 428
Cdd:pfam07926   3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREaqqNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1213953156 429 LQLEMSLVQARYESQRIQLESELAvQLEQRVTERLAQ 465
Cdd:pfam07926  83 AKAELEESEESWEEQKKELEKELS-ELEKRIEDLNEQ 118
DUF4670 pfam15709
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...
386-554 4.32e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.


Pssm-ID: 464815 [Multi-domain]  Cd Length: 522  Bit Score: 40.71  E-value: 4.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 386 REKEKSQREAQAAWETQHQLALV------QSEVRRLEGE-LDTARRERDALQLEMslvQARYESQRIQLESELAVQLEQR 458
Cdd:pfam15709 328 REQEKASRDRLRAERAEMRRLEVerkrreQEEQRRLQQEqLERAEKMREELELEQ---QRRFEEIRLRKQRLEEERQRQE 404
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 459 VTERLAQAQESSLRQAASLR-EHHRKQLQDLSGQHQQElasqlaqfkveMAEREERQQQVAEDYELRLAREQARVCELQs 537
Cdd:pfam15709 405 EEERKQRLQLQAAQERARQQqEEFRRKLQELQRKKQQE-----------EAERAEAEKQRQKELEMQLAEEQKRLMEMA- 472
                         170
                  ....*....|....*..
gi 1213953156 538 gnqqlEEQRVELVERLQ 554
Cdd:pfam15709 473 -----EEERLEYQRQKQ 484
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
201-447 5.39e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 40.05  E-value: 5.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 201 ERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQL-----DKT-LARVVEGWNRHEAERTEVLRG----LQEEHQAAElt 270
Cdd:pfam19220  75 TRRLSAAEGELEELVARLAKLEAALREAEAAKEELrielrDKTaQAEALERQLAAETEQNRALEEenkaLREEAQAAE-- 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 271 rskqqETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEaeqqrccvlqeERDAARAGQLSEHRELET 350
Cdd:pfam19220 153 -----KALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLA-----------ELETQLDATRARLRALEG 216
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 351 LRAALEEERQtwaQQEHQLKEHYQALQEESQAQLEREKEKSQREA---QAAWETQHQLALVQSEVRRLEGELDTARRERD 427
Cdd:pfam19220 217 QLAAEQAERE---RAEAQLEEAVEAHRAERASLRMKLEALTARAAateQLLAEARNQLRDRDEAIRAAERRLKEASIERD 293
                         250       260
                  ....*....|....*....|
gi 1213953156 428 ALQLEMSLVQARYESQRIQL 447
Cdd:pfam19220 294 TLERRLAGLEADLERRTQQF 313
Filament pfam00038
Intermediate filament protein;
201-481 5.74e-03

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 39.90  E-value: 5.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 201 ERHIQSLQTRVLELQQQLAVAVAADRKK-DTMIEQLDKTLARVVEGWNRHEAErtevLRGLQEEHQAAEltrsKQQETVT 279
Cdd:pfam00038  24 EQQNKLLETKISELRQKKGAEPSRLYSLyEKEIEDLRRQLDTLTVERARLQLE----LDNLRLAAEDFR----QKYEDEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 280 RLEQSLSEAMEALNREQESARLQQREretleeerqaLTLRLEAEQQRCCVL----QEERDAARAGQLSEHRELET----- 350
Cdd:pfam00038  96 NLRTSAENDLVGLRKDLDEATLARVD----------LEAKIESLKEELAFLkknhEEEVRELQAQVSDTQVNVEMdaark 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 351 --LRAALEEERqtwAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDA 428
Cdd:pfam00038 166 ldLTSALAEIR---AQYEEIAAKNREEAEEWYQSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQKAS 242
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1213953156 429 LQLEMSLVQARYESQRIQLESELAvQLEqrvtERLAQAQESSLRQaasLREHH 481
Cdd:pfam00038 243 LERQLAETEERYELQLADYQELIS-ELE----AELQETRQEMARQ---LREYQ 287
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
251-522 6.93e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 6.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 251 AERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVL 330
Cdd:COG4372    48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 331 QEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQS 410
Cdd:COG4372   128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEK 207
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 411 EVRRLEGELDTARRERDALqLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQLQDLSG 490
Cdd:COG4372   208 LIESLPRELAEELLEAKDS-LEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELE 286
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1213953156 491 QHQQELASQLAQFKVEMAEREERQQQVAEDYE 522
Cdd:COG4372   287 ALEEAALELKLLALLLNLAALSLIGALEDALL 318
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
387-532 8.75e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 39.33  E-value: 8.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213953156 387 EKEKSQREAQAAwETQHQLALVQSEVRRLE---GELDTARRERDALQLEMSLVQARYESQRIQLESelaVQLEQRVTERL 463
Cdd:pfam00529  57 QAALDSAEAQLA-KAQAQVARLQAELDRLQaleSELAISRQDYDGATAQLRAAQAAVKAAQAQLAQ---AQIDLARRRVL 132
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1213953156 464 AQAQESSLRQAASLREhHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARV 532
Cdd:pfam00529 133 APIGGISRESLVTAGA-LVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAEL 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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