NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1217329985|ref|NP_001340571|]
View 

NAD kinase isoform 4 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
pnk super family cl28462
bifunctional NADP phosphatase/NAD kinase;
9-346 8.00e-95

bifunctional NADP phosphatase/NAD kinase;


The actual alignment was detected with superfamily member PLN02727:

Pssm-ID: 333282 [Multi-domain]  Cd Length: 986  Bit Score: 303.35  E-value: 8.00e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985   9 QRLTWNKSPKSVLVIKKMRDAsLLQPFKELCTHLM-EENMIVYVEKKVLEdpAIASDESFGAVKkkfcTF-REDYDDISN 86
Cdd:PLN02727  670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYhQEKMNVLVEPDVHD--IFARIPGFGFVQ----TFySQDTSDLHE 742

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  87 QIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAA-----VVLRSRLKVRVVKel 161
Cdd:PLN02727  743 RVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR-- 820

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 162 rgkktavhnglgeNGSQAAGLDMDVgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 241
Cdd:PLN02727  821 -------------NGKAMPGKVFDV---------LNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYS 878

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 242 AAAGASMIHPNVPAIMITPICPHSLSFRPIVVP--AGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLP 319
Cdd:PLN02727  879 TAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLELKI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLP 956

                         330       340
                  ....*....|....*....|....*..
gi 1217329985 320 SICVRDPVSDWFESLAQCLHWNVRKKQ 346
Cdd:PLN02727  957 TVNKSDQTGDWFRSLIRCLNWNERLDQ 983
 
Name Accession Description Interval E-value
PLN02727 PLN02727
NAD kinase
 9-346 8.00e-95

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 303.35  E-value: 8.00e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985   9 QRLTWNKSPKSVLVIKKMRDAsLLQPFKELCTHLM-EENMIVYVEKKVLEdpAIASDESFGAVKkkfcTF-REDYDDISN 86
Cdd:PLN02727  670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYhQEKMNVLVEPDVHD--IFARIPGFGFVQ----TFySQDTSDLHE 742

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  87 QIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAA-----VVLRSRLKVRVVKel 161
Cdd:PLN02727  743 RVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR-- 820

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 162 rgkktavhnglgeNGSQAAGLDMDVgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 241
Cdd:PLN02727  821 -------------NGKAMPGKVFDV---------LNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYS 878

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 242 AAAGASMIHPNVPAIMITPICPHSLSFRPIVVP--AGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLP 319
Cdd:PLN02727  879 TAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLELKI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLP 956

                         330       340
                  ....*....|....*....|....*..
gi 1217329985 320 SICVRDPVSDWFESLAQCLHWNVRKKQ 346
Cdd:PLN02727  957 TVNKSDQTGDWFRSLIRCLNWNERLDQ 983
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
18-343 2.81e-60

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 195.36  E-value: 2.81e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  18 KSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAiasdesfgavkkkfctfreDYDDISNQIDFIICLGGD 97
Cdd:COG0061     2 KRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTAVPGV-------------------PLEELGEEADLVIVLGGD 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  98 GTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKElrgkktavhnglgengs 177
Cdd:COG0061    63 GTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRD----------------- 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 178 qaagldmdvGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTgstayaaaagasMIHPNVPAIM 257
Cdd:COG0061   126 ---------GEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgstaynlsaggpIVHPGLDALV 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 258 ITPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTSCYPLpSIcVRDPVSDWFESLAQC 337
Cdd:COG0061   197 LTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRP-AVLVADGQEVRDLEPGDRVEIRRSPKPV-RL-LRLKDHSFFERLREK 273


                  ....*.
gi 1217329985 338 LHWNVR 343
Cdd:COG0061   274 LGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 196-321 2.40e-31

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 115.09  E-value: 2.40e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 196 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPA 275
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1217329985 276 GVELKIMlsPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSI 321
Cdd:pfam20143  81 SSKLRIR--VLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
 
Name Accession Description Interval E-value
PLN02727 PLN02727
NAD kinase
 9-346 8.00e-95

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 303.35  E-value: 8.00e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985   9 QRLTWNKSPKSVLVIKKMRDAsLLQPFKELCTHLM-EENMIVYVEKKVLEdpAIASDESFGAVKkkfcTF-REDYDDISN 86
Cdd:PLN02727  670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYhQEKMNVLVEPDVHD--IFARIPGFGFVQ----TFySQDTSDLHE 742

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  87 QIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAA-----VVLRSRLKVRVVKel 161
Cdd:PLN02727  743 RVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR-- 820

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 162 rgkktavhnglgeNGSQAAGLDMDVgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 241
Cdd:PLN02727  821 -------------NGKAMPGKVFDV---------LNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYS 878

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 242 AAAGASMIHPNVPAIMITPICPHSLSFRPIVVP--AGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLP 319
Cdd:PLN02727  879 TAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLELKI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLP 956

                         330       340
                  ....*....|....*....|....*..
gi 1217329985 320 SICVRDPVSDWFESLAQCLHWNVRKKQ 346
Cdd:PLN02727  957 TVNKSDQTGDWFRSLIRCLNWNERLDQ 983
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 11-346 1.97e-90

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 280.18  E-value: 1.97e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  11 LTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMI-VYVEKKVLEDpAIASDESFGAVKKkfCTFREDYDDISNQID 89
Cdd:PLN02935  188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLnIYVEPRVKKE-LLSESSYFNFVQT--WEDEKEILLLHTKVD 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  90 FIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKElrgkktAVH 169
Cdd:PLN02935  265 LVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRD------AAK 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 170 NGLGENGSqaagldmdvgkqamqYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMI 249
Cdd:PLN02935  339 NEYETEEP---------------ILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMV 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 250 HPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSD 329
Cdd:PLN02935  404 HPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVESTND 483

                         330
                  ....*....|....*..
gi 1217329985 330 WFESLAQCLHWNVRKKQ 346
Cdd:PLN02935  484 FLRSIHDGLHWNLRKTQ 500
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
18-343 2.81e-60

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 195.36  E-value: 2.81e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  18 KSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAiasdesfgavkkkfctfreDYDDISNQIDFIICLGGD 97
Cdd:COG0061     2 KRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTAVPGV-------------------PLEELGEEADLVIVLGGD 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  98 GTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKElrgkktavhnglgengs 177
Cdd:COG0061    63 GTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRD----------------- 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 178 qaagldmdvGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTgstayaaaagasMIHPNVPAIM 257
Cdd:COG0061   126 ---------GEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgstaynlsaggpIVHPGLDALV 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 258 ITPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTSCYPLpSIcVRDPVSDWFESLAQC 337
Cdd:COG0061   197 LTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRP-AVLVADGQEVRDLEPGDRVEIRRSPKPV-RL-LRLKDHSFFERLREK 273


                  ....*.
gi 1217329985 338 LHWNVR 343
Cdd:COG0061   274 LGWGGD 279
ppnK PRK01231
NAD(+) kinase;
14-343 4.81e-38

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 137.78  E-value: 4.81e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  14 NKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLE-----DPAIASDESFGAVkkkfCtfredyddisnqi 88
Cdd:PRK01231    1 MPSFRNIGLIGRLGSSSVVETLRRLKDFLLDRGLEVILDEETAEvlpghGLQTVSRKLLGEV----C------------- 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  89 DFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVrvvkELRGKKTAV 168
Cdd:PRK01231   64 DLVIVVGGDGSLLGAARALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEA----EVRRGGEVI 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 169 HNGLGengsqaagldmdvgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASM 248
Cdd:PRK01231  140 GQGDA----------------------LNDVVLHPGKSTRMIEFELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPI 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 249 IHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDpvS 328
Cdd:PRK01231  198 MHPKLDAIVLVPMFPHTLSSRPIVVDGNSEIKIVISKDNRTYPRVSCDGQNSVTLAPGDTVTIRKKPQKLRLIHPLD--Y 275

                         330
                  ....*....|....*
gi 1217329985 329 DWFESLAQCLHWNVR 343
Cdd:PRK01231  276 NYYETCRTKLGWGSR 290
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
13-314 6.69e-38

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 142.94  E-value: 6.69e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  13 WNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEdpaiasdesfgAVKKKFCTFREDYDDISNqIDFII 92
Cdd:PRK14076  286 WRIKPTKFGIVSRIDNEEAINLALKIIKYLDSKGIPYELESFLYN-----------KLKNRLNEECNLIDDIEE-ISHII 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  93 CLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKelrgkktavhngl 172
Cdd:PRK14076  354 SIGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKEEIFKAIDSIISGEYEIEKRTKLSGFILK------------- 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 173 gengsqaagldmdVGKQAMQYQVLNEVVI-DRGPSSYLsNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHP 251
Cdd:PRK14076  421 -------------DGHQNILPSALNEVVItTKNPAKML-HFEVYVNGELVEEVRADGIIISTPTGSTAYSLSAGGPIVEP 486

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1217329985 252 NVPAIMITPICPHSLSFRPIVVPAGVELKIMLSpeaRNTAWVSFDGRKRQEIRHGDSISITTS 314
Cdd:PRK14076  487 TVDGFIIVPICPFKLSSRPLVVSANSEIKIKLL---KKSALVVIDGSIEFEAKKGDEIIFRKS 546
ppnK PRK02155
NAD kinase;
80-341 6.47e-33

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 123.90  E-value: 6.47e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  80 DYDDISNQIDFIICLGGDGTLL-YASSLFQGSVPPVMAFHlGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVV 158
Cdd:PRK02155   56 TPEEIGARADLAVVLGGDGTMLgIGRQLAPYGVPLIGINH-GRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVV 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 159 kelRGKKTaVHNGLgengsqaagldmdvgkqAMqyqvlNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGST 238
Cdd:PRK02155  135 ---RDGEP-IFHAL-----------------AF-----NDVVVNRSGFSGMVELRVSVDGRFMYNQRSDGLIVATPTGST 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 239 AYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSpEARNTAwVSFDGRKRQEIRHGDSISITTSCYpl 318
Cdd:PRK02155  189 AYALSAGGPILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQIV-GGRDVS-VNFDMQSLTSLELGDRIEVRRSPH-- 264

                         250       260
                  ....*....|....*....|....
gi 1217329985 319 pSICVRDPVS-DWFESLAQCLHWN 341
Cdd:PRK02155  265 -TVRFLHPVGySYYATLRKKLHWN 287
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 196-321 2.40e-31

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 115.09  E-value: 2.40e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 196 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPA 275
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1217329985 276 GVELKIMlsPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSI 321
Cdd:pfam20143  81 SSKLRIR--VLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 38-343 4.08e-31

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 119.58  E-value: 4.08e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  38 LCTHLMEENMIVYVEKKVLEDPAIASDESFGavkkkfCTFReDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAF 117
Cdd:PRK04539   26 LITFLKQHGFTVYLDEVGIKEGCIYTQDTVG------CHIV-NKTELGQYCDLVAVLGGDGTFLSVAREIAPRAVPIIGI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 118 HLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKElrgkktavhnglgengsqaagldmdvGKQAMQYQVLN 197
Cdd:PRK04539   99 NQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIRE--------------------------GKTAERALALN 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 198 EVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGV 277
Cdd:PRK04539  153 DAVLSRGGAGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTS 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1217329985 278 ELKIMLSP--EARntawVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDpvSDWFESLAQCLHWNVR 343
Cdd:PRK04539  233 EIEILVTQggDAR----VHFDGQTHIDVQNLDRITIRRYRNPLRILHPTD--YQYFKTLRQKLHWGEQ 294
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 36-298 1.69e-29

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 115.02  E-value: 1.69e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  36 KELCTHLMEENMIVYVEKKVLEdpAIASDESFgavKKKFCTFrEDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVM 115
Cdd:PRK01911   19 QELFDELEERGAEVLIEEKFLD--FLKQDLKF---HPSYDTF-SDNEELDGSADMVISIGGDGTFLRTATYVGNSNIPIL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 116 AFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGkktavhnglgenGSQAAgldmdvgkqamqyqv 195
Cdd:PRK01911   93 GINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQLESNPKLFG------------ELNFA--------------- 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 196 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPA 275
Cdd:PRK01911  146 LNEIAILKRDTSSMITVHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPD 225

                         250       260
                  ....*....|....*....|....
gi 1217329985 276 GVElkIMLSPEARNTAW-VSFDGR 298
Cdd:PRK01911  226 DTE--ITLEVESRSDNFlVSLDSR 247
ppnK PRK01185
NAD(+) kinase;
89-314 4.70e-28

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 110.67  E-value: 4.70e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  89 DFIICLGGDGTLLYASSLFQGsvpPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVvkelrgkktav 168
Cdd:PRK01185   54 DVIITIGGDGTILRTLQRAKG---PILGINMGGLGFLTEIEIDEVGSAIKKLIRGEYFIDERMKLKVYI----------- 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 169 hnglgeNGSQAagldmdvgkqamqYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASM 248
Cdd:PRK01185  120 ------NGERL-------------EDCTNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSSSAGGPI 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1217329985 249 IHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTawVSFDGRKRQEIRHGDSISITTS 314
Cdd:PRK01185  181 LLPNLEGMVISYIAPYSSRPKSVVVPSESTVEIKIAGDQSSL--LILDGQYEYKISKGDTVEISKS 244
ppnK PRK03708
NAD(+) kinase;
72-314 1.12e-26

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 107.10  E-value: 1.12e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  72 KKFCTFRE-DYDDISN-QIDFIICLGGDGTLLYASSLFQGSVpPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVvl 149
Cdd:PRK03708   40 EHLPEFSEeDVLPLEEmDVDFIIAIGGDGTILRIEHKTKKDI-PILGINMGTLGFLTEVEPEETFFALSRLLEGDYFI-- 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 150 RSRLKVRVvkelrgkktaVHNglGENGSQAagldmdvgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGV 229
Cdd:PRK03708  117 DERIKLRV----------YIN--GENVPDA----------------LNEVVILTGIPGKIIHLKYYVDGELADEVRADGL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 230 IVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSI 309
Cdd:PRK03708  169 IISTPTGSTAYAMSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSRIDVKLLRTGRE-IILVIDGQYYEELPPDTEI 247


                  ....*
gi 1217329985 310 SITTS 314
Cdd:PRK03708  248 TIKKS 252
ppnK PRK02645
NAD(+) kinase;
85-340 1.08e-24

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 101.91  E-value: 1.08e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  85 SNQIDFIICLGGDGTLLYAS-SLFQGSVPpVMAFHLG-SLGFLT-PFSFENFQSQVTQVIEGNAAVVLRSRLKVRVvkeL 161
Cdd:PRK02645   55 SELIDLAIVLGGDGTVLAAArHLAPHDIP-ILSVNVGgHLGFLThPRDLLQDESVWDRLQEDRYAIERRMMLQARV---F 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 162 RGKKTavhnglgengsqaagldmDVGKQAMQYQVLNE-----VVIDRGPSSYLsnvDVYLDGHLITTVQGDGVIVSTPTG 236
Cdd:PRK02645  131 EGDRS------------------NEEPVSESYYALNDfylkpASEDRSPTCIL---ELEIDGEVVDQYQGDGLIVSTPTG 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 237 STAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAG--VELKIMLSPEARNTAWVsfDGRKRQEIRHGDSISITTS 314
Cdd:PRK02645  190 STAYTMAAGGPILHPGIDAIIVTPICPMSLSSRPIVIPPGsrVVIWPLGDYDLNIKLWK--DGVLATSIWPGQRCVIQKA 267

                         250       260
                  ....*....|....*....|....*.
gi 1217329985 315 CYPLPSICVRDPVSdWFESLAQCLHW 340
Cdd:PRK02645  268 RHPAKFIILEESYS-YYRTLREKLHW 292
pnk PRK14077
NAD(+) kinase;
82-340 1.18e-24

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 101.78  E-value: 1.18e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  82 DDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKEl 161
Cdd:PRK14077   59 DELFKISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEIEKPYMLSVFLEKK- 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 162 RGKktavhnglgengsqaagldmdvgkqAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 241
Cdd:PRK14077  138 QGK-------------------------ILEKLAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGDGVIVATPAGSTAYN 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 242 AAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMlspeARNTAWVSFDGRKRQEIRHGDSISITTScyPLPSI 321
Cdd:PRK14077  193 MSANGPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEFK----TKSDCILCIDGQDRYKMNDFKSIKVGLS--DKNVA 266

                         250
                  ....*....|....*....
gi 1217329985 322 CVRDPVSDWFESLAQCLHW 340
Cdd:PRK14077  267 LIRHKNRDYFQILKEKLHW 285
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 22-318 1.87e-23

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 98.48  E-value: 1.87e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  22 VIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIaSDESFGavkkkfctfreDYDDISNQIDFIICLGGDGTLL 101
Cdd:PRK03378   10 IVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQL-KNVKTG-----------TLAEIGQQADLAIVVGGDGNML 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 102 YAS---SLFQGSVPPVmafHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKelrgkktavHNGLGENGSq 178
Cdd:PRK03378   78 GAArvlARYDIKVIGI---NRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCR---------HGQQKRIST- 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 179 aagldmdvgkqamqyqVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMI 258
Cdd:PRK03378  145 ----------------AINEVVLHPGKVAHMIEFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITL 208

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 259 TPICPHSLSFRPIVVPAGVELKIMLSPEaRNTAWVSFDGRKRQEIRHGDSISITTSCYPL 318
Cdd:PRK03378  209 VPMFPHTLSARPLVIDSSSTIRLKFSPN-RSDLEISCDSQIALPIQPGEEVLIRRSDYHL 267
ppnK PRK02649
NAD(+) kinase;
88-340 2.40e-19

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 86.96  E-value: 2.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  88 IDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVvkeLRGKKTa 167
Cdd:PRK02649   69 MKFAIVLGGDGTVLSAARQLAPCGIPLLTINTGHLGFLTEAYLNQLDEAIDQVLAGQYTIEERTMLTVSV---MRGDQL- 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 168 vhngLGENGSqaagldmdvgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGAS 247
Cdd:PRK02649  145 ----RWEALS------------------LNEMVLHREPLTSMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGP 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 248 MIHPNVPAIMITPICPHSLSFRPIVVPAGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPv 327
Cdd:PRK02649  203 VITPDVPVLQLTPICPHSLASRALVFSDSEPVTV--FPATPERLVMVVDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDP- 279

                         250
                  ....*....|...
gi 1217329985 328 sDWFESLAQCLHW 340
Cdd:PRK02649  280 -EFFRVLREKLGW 291
ppnK PRK02231
NAD(+) kinase;
42-340 4.11e-16

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 77.54  E-value: 4.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  42 LMEENMIVYVEKKVLEDPAIASDESfgavkkkfctfrEDYDDISNQIDFIICLGGDGTLL-YASSLFQGSVPpVMAFHLG 120
Cdd:PRK02231    9 LKERGYQVLVEKEIAEQLNLPENHL------------ASLEEIGQRAQLAIVIGGDGNMLgRARVLAKYDIP-LIGINRG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 121 SLGFLTPFSFENFQSQVTQVIE-GNAAVVLRSRLKVRVvkELRGKKTAVHNGLgengsqaagldmdvgkqamqyqvlNEV 199
Cdd:PRK02231   76 NLGFLTDIDPKNAYEQLEACLErGEFFVEERFLLEAKI--ERNGKIIATSNAL------------------------NEV 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 200 VIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVEL 279
Cdd:PRK02231  130 VIHPAKIAHMIDFHVYIDDKFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVIDGDSKI 209

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1217329985 280 KIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDpvSDWFESLAQCLHW 340
Cdd:PRK02231  210 SLRFAEYNTPQLEVSCDSQIALPFTPDDRVHVQKSPDKLRLLHLKN--YNYYNVLSSKLGW 268
pnk PRK14075
NAD(+) kinase;
88-274 2.32e-15

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 74.77  E-value: 2.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  88 IDFIICLGGDGTLLYASSLFQGsvpPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKelrgkkta 167
Cdd:PRK14075   42 ADLIIVVGGDGTVLKAAKKVGT---PLVGFKAGRLGFLSSYTLEEIDRFLEDLKNWNFREEKRWFLKIESEL-------- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 168 vhnglgengsqaagldmdvgkqaMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGAS 247
Cdd:PRK14075  111 -----------------------GNHLALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGSTAYSLSLGGP 167

                         170       180
                  ....*....|....*....|....*..
gi 1217329985 248 MIHPNVPAIMITPICPHSLSFRPIVVP 274
Cdd:PRK14075  168 IILPNCEVFEITPIAPQFLATRSIVIP 194
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 20-142 3.71e-15

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 71.24  E-value: 3.71e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  20 VLVIKKMRDASLLQPFKELCTHLMEENMI-VYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDDISNQI----DFIICL 94
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLDRLGItVTVEEKMGESLAFAAGDRPEVIGCLKKVVDDTRRATRAFAdagvDLIIVL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1217329985  95 GGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIE 142
Cdd:pfam01513  81 GGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 55-318 1.72e-13

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 70.33  E-value: 1.72e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  55 VLEDPAIASDESFGAV---KKKFCTFREDyDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFE 131
Cdd:PRK03372   38 RVLDAEAVDLGATHPApddFRAMEVVDAD-PDAADGCELVLVLGGDGTILRAAELARAADVPVLGVNLGHVGFLAEAEAE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 132 NFQSQVTQVIEGNAAVVLRSRLKVRVvkelRGKKTAVHNGLGengsqaagldmdvgkqamqyqvLNEVVIDRGPSSYLSN 211
Cdd:PRK03372  117 DLDEAVERVVDRDYRVEERMTLDVTV----RVGGEIVWRGWA----------------------LNEASLEKADREGMLE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 212 VDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEArNTA 291
Cdd:PRK03372  171 VVLEVDGRPVSSFGCDGVLVSTPTGSTAYAFSAGGPVVWPDLEALLVVPLNAHALFARPLVVSPTSTVAVEILADT-SDA 249

                         250       260
                  ....*....|....*....|....*..
gi 1217329985 292 WVSFDGRKRQEIRHGDSISITTSCYPL 318
Cdd:PRK03372  250 VLWCDGRRSVDLPPGARVEVRRGATPV 276
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 71-311 1.39e-10

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 60.99  E-value: 1.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  71 KKKFCTFREDYDDisNQIDFIICLGGDGTLLYASSLFQGSVPPVmAF---HLGSLGFLT---PFSFENFqsqVTQVIEGN 144
Cdd:PRK04885   21 KKYLKDFGFILDE--KNPDIVISVGGDGTLLSAFHRYENQLDKV-RFvgvHTGHLGFYTdwrPFEVDKL---VIALAKDP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 145 AAVVLRSRLKVRVVKElrgkktavhnglgeNGSQAAgldmdvgkqamqYQVLNEVVIDRgPSSYLSnVDVYLDGHLITTV 224
Cdd:PRK04885   95 GQVVSYPLLEVKITYE--------------DGEKEK------------YLALNEATIKR-IEGTLV-ADVYINGVLFERF 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 225 QGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICphSLS---FR----PIVVPAGVelKIMLSPEARNTAWVSFDg 297
Cdd:PRK04885  147 RGDGLCVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIA--SINnrvFRtlgsPLILPKHH--TITLKPVNDDDYQITVD- 221

                         250
                  ....*....|....
gi 1217329985 298 rkRQEIRHGDSISI 311
Cdd:PRK04885  222 --HLTIKHKNVKSI 233
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 81-234 2.56e-04

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 42.11  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  81 YDDIS-NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFL-TPFSFENFQSQVtqviegNAAVVLRSRLKVRVV 158
Cdd:PRK04761   18 YGDVPiEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLmNEYSEDDLLERI------AAAEPTVLHPLRMTA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 159 KELRGKktaVHNGLGEN-------GSQAAGLDMDV-GKQAMQyqvlnEVVidrgpssylsnvdvyldghlittvqGDGVI 230
Cdd:PRK04761   92 TDVSGE---VHEALAINevslfrqTRQAAKLRISIdGKVRME-----ELV-------------------------CDGVL 138


                  ....
gi 1217329985 231 VSTP 234
Cdd:PRK04761  139 VATP 142
PLN02929 PLN02929
NADH kinase
 75-157 2.25e-03

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 39.25  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  75 CTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPvmafhLG----------------------SLGFLTPFSFEN 132
Cdd:PLN02929   52 CVLRNELSQPIRDVDLVVAVGGDGTLLQASHFLDDSIPV-----LGvnsdptqkdeveeysdefdarrSTGHLCAATAED 126

                          90       100
                  ....*....|....*....|....*
gi 1217329985 133 FQSQVTQVIEGNAAVVLRSRLKVRV 157
Cdd:PLN02929  127 FEQVLDDVLFGRLKPTELSRISTVV 151
ppnK PRK03501
NAD kinase;
189-235 2.34e-03

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 39.19  E-value: 2.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1217329985 189 QAMQYQVLNEVVIDrgpSSYLSN--VDVYLDGHLITTVQGDGVIVSTPT 235
Cdd:PRK03501  113 GSTSFYCLNEFSIR---SSIIKTfvIDVYIDDLHFETFRGDGMVVSTPT 158
ppnK PRK00561
NAD(+) kinase;
86-311 7.61e-03

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 37.55  E-value: 7.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985  86 NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSF----ENFQSQVTQviegnaavvlrsrLKVRVVKEL 161
Cdd:PRK00561   32 DGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNEtdldQNFANKLDQ-------------LKFTQIDLL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1217329985 162 RgkktavhnglgengsqaagldmdVGKQAMQYQVLNEVVIDrgpSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 241
Cdd:PRK00561   99 E-----------------------VQIDDQIHLVLNELAVY---TNTAYPINIFIDNEFWEKYRGSGLLIGPRTGSTALA 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1217329985 242 AAAGASMIHPNVPAIMITPICP--HSlSF----RPIVVPAGVELKIMLSPEARNTAWVSF--DGRKRQEIRHGDSISI 311
Cdd:PRK00561  153 KSAKGAVIFPRIDVIQIIELNPllHP-NQttiqSPIILPIDTKVEFEIKKAFDHDQFPRFyaDGAKLRLGNSDTTIEI 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH