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Conserved domains on  [gi|1230839339|ref|NP_001341383|]
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phospholipid phosphatase 5 isoform 5 [Homo sapiens]

Protein Classification

phosphatase PAP2 family protein( domain architecture ID 10130247)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to mammalian phospholipid phosphatases that catalyzes the conversion of phosphatidic acid to diacylglycerol

EC:  3.1.3.-
Gene Ontology:  GO:0006644|GO:0008195|GO:0046839
PubMed:  12447906

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 43-240 1.24e-61

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


:

Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 191.66  E-value: 1.24e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  43 WLYRNPYVEAEYFPTKPMFVrgerssflpphdpasrghlcvfhpetafvIAFLSPLSLIFLAKFLKKADTRDSRQACLAA 122
Cdd:cd03390     1 PSISYPFAESETVPTWLLVI-----------------------------ISVGIPLLVIILISLFFRRSLWDLHTSLLGL 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 123 SLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLAHSDLM------CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYL 196
Cdd:cd03390    52 LLSVSLNGVITNVLKNYAGRPRPDFLARCFPDGGTPSDTLvgidicCTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYL 131

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1230839339 197 AGKLHCFTPqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQ 240
Cdd:cd03390   132 AGKLHIFDP--RGSSWRLLLALLPLLLAILVAVSRTRDYRHHFS 173
 
Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 43-240 1.24e-61

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 191.66  E-value: 1.24e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  43 WLYRNPYVEAEYFPTKPMFVrgerssflpphdpasrghlcvfhpetafvIAFLSPLSLIFLAKFLKKADTRDSRQACLAA 122
Cdd:cd03390     1 PSISYPFAESETVPTWLLVI-----------------------------ISVGIPLLVIILISLFFRRSLWDLHTSLLGL 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 123 SLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLAHSDLM------CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYL 196
Cdd:cd03390    52 LLSVSLNGVITNVLKNYAGRPRPDFLARCFPDGGTPSDTLvgidicCTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYL 131

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1230839339 197 AGKLHCFTPqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQ 240
Cdd:cd03390   132 AGKLHIFDP--RGSSWRLLLALLPLLLAILVAVSRTRDYRHHFS 173
PLN02250 PLN02250
lipid phosphate phosphatase
 91-243 1.18e-44

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 152.00  E-value: 1.18e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  91 VIAFLSPLSLIFLAKFLKKaDTRDSRQACLAASLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLA-----HSDLMCTG 165
Cdd:PLN02250   73 LIAILLPFAVILVYYFIRR-DVYDLHHAILGLLFSVLITGVITDAIKDAVGRPRPDFFWRCFPDGKGvfhpvTTDVLCTG 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1230839339 166 DKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFtpQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQGPF 243
Cdd:PLN02250  152 AKSVIKEGHKSFPSGHTSWSFAGLGFLSLYLSGKIRVF--DRRGHVAKLCIVFLPLLVAALVGVSRVDDYWHHWQDVF 227
acidPPc smart00014
Acid phosphatase homologues;
132-239 3.05e-16

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 72.38  E-value: 3.05e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  132 FTNTIKLIVGRPRPDFFYRCfpdglahsDLMCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpQGRGKS 211
Cdd:smart00014  10 FNGVIKNYFGRPRPFFLSIG--------DACCTPNFLLTLEAGYSFPSGHTAFAFAFALFLLLYL---------PARAGR 72

                           90       100
                   ....*....|....*....|....*...
gi 1230839339  212 WRFCAFLspLLFAAVIALSRTCDYKHHW 239
Cdd:smart00014  73 KLLIFLL--LLLALVVGFSRVYLGAHWP 98
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 130-239 2.50e-15

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 70.14  E-value: 2.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 130 GVFTNTIKLIVGRPRPDFFYRCFPDGLAHSDLMctgdkdvvnEGRKSFPSGHSSFAFAGLAFASFYLAgklhcftpqGRG 209
Cdd:pfam01569  10 GLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTLP---------GLGYSFPSGHSATAFALALLLALLLR---------RLR 71

                          90       100       110
                  ....*....|....*....|....*....|
gi 1230839339 210 KSWRFCAFLSPLLFAAVIALSRTCDYKHHW 239
Cdd:pfam01569  72 KIVRVLLALLLLVLALLVGLSRLYLGVHFP 101
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 88-231 1.48e-05

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 44.26  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  88 TAFVIAFLSPLSLIFLAKFLKKADTRDSRQACLAASLALALNGVFTNTIKLIVGRPRPdFFYRCFPDGLAHSDlmctgdk 167
Cdd:COG0671    44 LLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRP-FVVPDLELLLGTAG------- 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1230839339 168 dvvnegRKSFPSGHSSFAFAGLAFASFYLagklhcftpqgrgksWRFCAFLSPLLFAAVIALSR 231
Cdd:COG0671   116 ------GYSFPSGHAAAAFALALVLALLL---------------PRRWLAALLLALALLVGLSR 158
 
Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 43-240 1.24e-61

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 191.66  E-value: 1.24e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  43 WLYRNPYVEAEYFPTKPMFVrgerssflpphdpasrghlcvfhpetafvIAFLSPLSLIFLAKFLKKADTRDSRQACLAA 122
Cdd:cd03390     1 PSISYPFAESETVPTWLLVI-----------------------------ISVGIPLLVIILISLFFRRSLWDLHTSLLGL 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 123 SLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLAHSDLM------CTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYL 196
Cdd:cd03390    52 LLSVSLNGVITNVLKNYAGRPRPDFLARCFPDGGTPSDTLvgidicCTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYL 131

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1230839339 197 AGKLHCFTPqgRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQ 240
Cdd:cd03390   132 AGKLHIFDP--RGSSWRLLLALLPLLLAILVAVSRTRDYRHHFS 173
PLN02250 PLN02250
lipid phosphate phosphatase
 91-243 1.18e-44

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 152.00  E-value: 1.18e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  91 VIAFLSPLSLIFLAKFLKKaDTRDSRQACLAASLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLA-----HSDLMCTG 165
Cdd:PLN02250   73 LIAILLPFAVILVYYFIRR-DVYDLHHAILGLLFSVLITGVITDAIKDAVGRPRPDFFWRCFPDGKGvfhpvTTDVLCTG 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1230839339 166 DKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFtpQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQGPF 243
Cdd:PLN02250  152 AKSVIKEGHKSFPSGHTSWSFAGLGFLSLYLSGKIRVF--DRRGHVAKLCIVFLPLLVAALVGVSRVDDYWHHWQDVF 227
PLN02731 PLN02731
Putative lipid phosphate phosphatase
 91-243 5.85e-39

Putative lipid phosphate phosphatase


Pssm-ID: 178332  Cd Length: 333  Bit Score: 137.85  E-value: 5.85e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  91 VIAFLSPLsLIFLAKFLKKADTRDSRQACLAASLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLAH----SDLMCTGD 166
Cdd:PLN02731   92 VYAMLLPL-VIFIFIYFRRRDVYDLHHAVLGLLYSVLVTAVLTDAIKNAVGRPRPDFFWRCFPDGKALydslGDVICHGD 170

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1230839339 167 KDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFtpQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQGPF 243
Cdd:PLN02731  171 KSVIREGHKSFPSGHTSWSFSGLGFLSLYLSGKIQAF--DGKGHVAKLCIVILPLLFAALVGISRVDDYWHHWQDVF 245
PLN02715 PLN02715
lipid phosphate phosphatase
 91-243 1.83e-32

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 120.54  E-value: 1.83e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  91 VIAFLSPLsLIFLAKFLKKADTRDSRQACLAASLALALNGVFTNTIKLIVGRPRPDFFYRCFPDGLAHSD----LMCTGD 166
Cdd:PLN02715   98 VYAVLLPI-ILFVCFYLKRRCVYDLHHSILGLLFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKELYDalggVICHGK 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1230839339 167 KDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKswRFCAFLSPLLFAAVIALSRTCDYKHHWQGPF 243
Cdd:PLN02715  177 AAEVKEGHKSFPSGHTSWSFAGLTFLSLYLSGKIKAFNGEGHVA--KLCLVIFPLLAACLVGISRVDDYWHHWQDVF 251
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 131-239 9.68e-24

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 93.08  E-value: 9.68e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 131 VFTNTIKLIVGRPRPDFFYRCFPDG----------LAHSDLMCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKL 200
Cdd:cd03384    18 LLTDLGKYVTGRLRPHFLDVCKPNYtdltcsldhqYIADCTCCTGDPDLIREARLSFPSGHASLSMYAAVFLALYLQARL 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1230839339 201 hcftpqgrgkSWRFCAFLSPLL------FAAVIALSRTCDYKHHW 239
Cdd:cd03384    98 ----------KLRGSRLLRPLLqflllaLALYVGLSRISDYKHHW 132
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 129-239 8.30e-18

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 76.73  E-value: 8.30e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 129 NGVFTNTIKLIVGRPRPDFFYRCFPDGlahsdlmctgDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLhcftpqgr 208
Cdd:cd01610    15 GLLLTGVLKYLFGRPRPYFLLRCGPDG----------DPLLLTEGGYSFPSGHAAFAFALALFLALLLPRRL-------- 76

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1230839339 209 gksWRFCAFLSPLLFAAVIALSRTCDYKHHW 239
Cdd:cd01610    77 ---LRLLLGLLLLLLALLVGLSRVYLGVHYP 104
acidPPc smart00014
Acid phosphatase homologues;
132-239 3.05e-16

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 72.38  E-value: 3.05e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  132 FTNTIKLIVGRPRPDFFYRCfpdglahsDLMCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLagklhcftpQGRGKS 211
Cdd:smart00014  10 FNGVIKNYFGRPRPFFLSIG--------DACCTPNFLLTLEAGYSFPSGHTAFAFAFALFLLLYL---------PARAGR 72

                           90       100
                   ....*....|....*....|....*...
gi 1230839339  212 WRFCAFLspLLFAAVIALSRTCDYKHHW 239
Cdd:smart00014  73 KLLIFLL--LLLALVVGFSRVYLGAHWP 98
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 130-239 2.50e-15

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 70.14  E-value: 2.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 130 GVFTNTIKLIVGRPRPDFFYRCFPDGLAHSDLMctgdkdvvnEGRKSFPSGHSSFAFAGLAFASFYLAgklhcftpqGRG 209
Cdd:pfam01569  10 GLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTLP---------GLGYSFPSGHSATAFALALLLALLLR---------RLR 71

                          90       100       110
                  ....*....|....*....|....*....|
gi 1230839339 210 KSWRFCAFLSPLLFAAVIALSRTCDYKHHW 239
Cdd:pfam01569  72 KIVRVLLALLLLVLALLVGLSRLYLGVHFP 101
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 130-231 4.54e-08

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 51.46  E-value: 4.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 130 GVFTNTIKLIVGRPRPDFFYRCFPDGLahsdlmctgdkdvvnegrkSFPSGHSSFAFAGLAFASFYLAGKLHcftpqgrG 209
Cdd:cd03392    75 GALNTLLKLLVQRPRPPLHLLVPEGGY-------------------SFPSGHAMGATVLYGFLAYLLARRLP-------R 128

                          90       100
                  ....*....|....*....|..
gi 1230839339 210 KSWRFCAFLSPLLFAAVIALSR 231
Cdd:cd03392   129 RRVRILLLILAAILILLVGLSR 150
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 88-231 1.48e-05

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 44.26  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339  88 TAFVIAFLSPLSLIFLAKFLKKADTRDSRQACLAASLALALNGVFTNTIKLIVGRPRPdFFYRCFPDGLAHSDlmctgdk 167
Cdd:COG0671    44 LLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRP-FVVPDLELLLGTAG------- 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1230839339 168 dvvnegRKSFPSGHSSFAFAGLAFASFYLagklhcftpqgrgksWRFCAFLSPLLFAAVIALSR 231
Cdd:COG0671   116 ------GYSFPSGHAAAAFALALVLALLL---------------PRRWLAALLLALALLVGLSR 158
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 130-237 1.95e-05

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 43.85  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 130 GVFTNTIKLIVGRPRPDFFyrcFPDGLAHSDLMCTGDkdvvneGRKSFPSGHSSFAFAgLAFASFYLAGKlhcftpqgrg 209
Cdd:cd03389    82 GILVNLLKFIIGRARPKLL---FDDGLYGFDPFHADY------AFTSFPSGHSATAGA-AAAALALLFPR---------- 141

                          90       100
                  ....*....|....*....|....*...
gi 1230839339 210 ksWRFCAflspLLFAAVIALSRTCDYKH 237
Cdd:cd03389   142 --YRWAF----ILLALLIAFSRVIVGAH 163
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 133-194 6.02e-05

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 41.16  E-value: 6.02e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1230839339 133 TNTIKLIVGRPRPDffyrcfpdglahsdlmctGDkdvvNEGRKSFPSGHSSFAFAGLAFASF 194
Cdd:cd03394    19 TEGLKFAVGRARPD------------------GS----NNGYRSFPSGHTASAFAAATFLQY 58
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 136-238 2.25e-03

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 37.68  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1230839339 136 IKLIVGRPRPdffyrcfpdglAHsdlMCTGDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHcftpqgrgkswrfc 215
Cdd:cd03391    66 LKALVRRRRP-----------AY---NSPDMLDYVAVDKYSFPSGHASRAAFVARFLLNHLVLAVP-------------- 117

                          90       100
                  ....*....|....*....|....
gi 1230839339 216 aFLSPL-LFAAVIALSRTCDYKHH 238
Cdd:cd03391   118 -LRVLLvLWATVVGISRVLLGRHH 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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