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Conserved domains on  [gi|1238280285|ref|NP_001341873|]
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cullin-4A isoform 6 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cullin super family cl38017
Cullin family;
2-70 1.17e-18

Cullin family;


The actual alignment was detected with superfamily member pfam00888:

Pssm-ID: 459983 [Multi-domain]  Cd Length: 610  Bit Score: 77.99  E-value: 1.17e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238280285   2 LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVlqnSTLPSI 70
Cdd:pfam00888  40 LYDKLKEYLEEHLKKLVKPLIKEASSGEEFLKAYVKEWEDHTISMKMIRDIFMYLDRVYV---KRLPSI 105
 
Name Accession Description Interval E-value
Cullin pfam00888
Cullin family;
2-70 1.17e-18

Cullin family;


Pssm-ID: 459983 [Multi-domain]  Cd Length: 610  Bit Score: 77.99  E-value: 1.17e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238280285   2 LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVlqnSTLPSI 70
Cdd:pfam00888  40 LYDKLKEYLEEHLKKLVKPLIKEASSGEEFLKAYVKEWEDHTISMKMIRDIFMYLDRVYV---KRLPSI 105
COG5647 COG5647
Cullin, a subunit of E3 ubiquitin ligase [Posttranslational modification, protein turnover, ...
 28-71 2.00e-03

Cullin, a subunit of E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227934 [Multi-domain]  Cd Length: 773  Bit Score: 34.78  E-value: 2.00e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1238280285  28 SVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIC 71
Cdd:COG5647   106 MEEFLDELVKFWNRFTKGATMINHLFLYMDRVYLKKARYDKTLV 149
 
Name Accession Description Interval E-value
Cullin pfam00888
Cullin family;
2-70 1.17e-18

Cullin family;


Pssm-ID: 459983 [Multi-domain]  Cd Length: 610  Bit Score: 77.99  E-value: 1.17e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1238280285   2 LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVlqnSTLPSI 70
Cdd:pfam00888  40 LYDKLKEYLEEHLKKLVKPLIKEASSGEEFLKAYVKEWEDHTISMKMIRDIFMYLDRVYV---KRLPSI 105
COG5647 COG5647
Cullin, a subunit of E3 ubiquitin ligase [Posttranslational modification, protein turnover, ...
 28-71 2.00e-03

Cullin, a subunit of E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227934 [Multi-domain]  Cd Length: 773  Bit Score: 34.78  E-value: 2.00e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1238280285  28 SVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIC 71
Cdd:COG5647   106 MEEFLDELVKFWNRFTKGATMINHLFLYMDRVYLKKARYDKTLV 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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