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Conserved domains on  [gi|1249618556|ref|NP_001343372|]
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tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 isoform 3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gcd10p super family cl04439
Gcd10p family; eIF-3 is a multi-subunit complex that stimulates translation initiation in ...
 1-82 9.45e-32

Gcd10p family; eIF-3 is a multi-subunit complex that stimulates translation initiation in vitro at several different steps. This family corresponds to the gamma subunit if eIF3. The Yeast protein Gcd10p has also been shown to be part of a complex with the methyltransferase Gcd14p that is involved in modifying tRNA.


The actual alignment was detected with superfamily member pfam04189:

Pssm-ID: 461216  Cd Length: 295  Bit Score: 120.36  E-value: 9.45e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618556   1 MYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGG--FGSIIQLYPGDGPVRAATACFGF-P 77
Cdd:pfam04189 175 YLEKKDPQKILDLREETLGLLLTWANVHPGGRYLVVDETGGLLVAAMAERMGGatTGTITVIHPNEQPNLSLLKYFNYdP 254


                  ....*
gi 1249618556  78 KSFLS 82
Cdd:pfam04189 255 EHPLD 259
 
Name Accession Description Interval E-value
Gcd10p pfam04189
Gcd10p family; eIF-3 is a multi-subunit complex that stimulates translation initiation in ...
 1-82 9.45e-32

Gcd10p family; eIF-3 is a multi-subunit complex that stimulates translation initiation in vitro at several different steps. This family corresponds to the gamma subunit if eIF3. The Yeast protein Gcd10p has also been shown to be part of a complex with the methyltransferase Gcd14p that is involved in modifying tRNA.


Pssm-ID: 461216  Cd Length: 295  Bit Score: 120.36  E-value: 9.45e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618556   1 MYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGG--FGSIIQLYPGDGPVRAATACFGF-P 77
Cdd:pfam04189 175 YLEKKDPQKILDLREETLGLLLTWANVHPGGRYLVVDETGGLLVAAMAERMGGatTGTITVIHPNEQPNLSLLKYFNYdP 254


                  ....*
gi 1249618556  78 KSFLS 82
Cdd:pfam04189 255 EHPLD 259
 
Name Accession Description Interval E-value
Gcd10p pfam04189
Gcd10p family; eIF-3 is a multi-subunit complex that stimulates translation initiation in ...
 1-82 9.45e-32

Gcd10p family; eIF-3 is a multi-subunit complex that stimulates translation initiation in vitro at several different steps. This family corresponds to the gamma subunit if eIF3. The Yeast protein Gcd10p has also been shown to be part of a complex with the methyltransferase Gcd14p that is involved in modifying tRNA.


Pssm-ID: 461216  Cd Length: 295  Bit Score: 120.36  E-value: 9.45e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618556   1 MYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCSGLVLGAMMERMGG--FGSIIQLYPGDGPVRAATACFGF-P 77
Cdd:pfam04189 175 YLEKKDPQKILDLREETLGLLLTWANVHPGGRYLVVDETGGLLVAAMAERMGGatTGTITVIHPNEQPNLSLLKYFNYdP 254


                  ....*
gi 1249618556  78 KSFLS 82
Cdd:pfam04189 255 EHPLD 259
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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