|
Name |
Accession |
Description |
Interval |
E-value |
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
89-270 |
1.05e-72 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 239.81 E-value: 1.05e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 89 ELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYE----KPIS 164
Cdd:pfam09727 1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 165 ELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 244
Cdd:pfam09727 81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160
|
170 180
....*....|....*....|....*.
gi 1270111431 245 AKRLNKLRDELVKLKSFALMLVDERQ 270
Cdd:pfam09727 161 KKLLEKLEEELSKQKQIALLLVKERK 186
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
220-753 |
1.95e-22 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 104.38 E-value: 1.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 220 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLKA 299
Cdd:PRK03918 188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLE---GSKRKLEEKIRE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 300 ITYKSKEDRQKLLKLEV---------DFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKA 370
Cdd:PRK03918 264 LEERIEELKKEIEELEEkvkelkelkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 371 EEELQELRDKIAKGECGNS------SLMAEVESLRKRVlemegKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQ 444
Cdd:PRK03918 344 KKKLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 445 KRMSELEKLEEAFSRSKSEC--TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVM 522
Cdd:PRK03918 419 KEIKELKKAIEELKKAKGKCpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 523 --LVDERKNM--------MEKIKQEERKVDGLNKNFKVEQGKVMDVtEKLIEESKKLLKLKSEMEEKVYSLTKERDELMG 592
Cdd:PRK03918 499 keLAEQLKELeeklkkynLEELEKKAEEYEKLKEKLIKLKGEIKSL-KKELEKLEELKKKLAELEKKLDELEEELAELLK 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 593 KLRSEEERScelscsVDLLKKRLDGIEEVEREINRgrlCKGSEFTCPEdnKIRELTLEIERLKKRLQQLEVVEGDLMKTE 672
Cdd:PRK03918 578 ELEELGFES------VEELEERLKELEPFYNEYLE---LKDAEKELER--EEKELKKLEEELDKAFEELAETEKRLEELR 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 673 DEYDQLEQKFRTEQ---------DKANFLSQQLEEIKHQMAKNKAIEKG-EAVSQEAELRHRFRMEEAKSRDLQAEVQAL 742
Cdd:PRK03918 647 KELEELEKKYSEEEyeelreeylELSRELAGLRAELEELEKRREEIKKTlEKLKEELEEREKAKKELEKLEKALERVEEL 726
|
570
....*....|.
gi 1270111431 743 KEKIHELMNKE 753
Cdd:PRK03918 727 REKVKKYKALL 737
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
47-778 |
3.96e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 87.50 E-value: 3.96e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 47 PSEDAKKNKANRKGEDDVMasgtvkRHLKPSGESEKKTKKPLELSKEDLIQLLSIMEgelQAREDVIHMLKTEKTKPEVL 126
Cdd:PTZ00121 1051 DIDGNHEGKAEAKAHVGQD------EGLKPSYKDFDFDAKEDNRADEATEEAFGKAE---EAKKTETGKAEEARKAEEAK 1121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 127 EAHYGSAEPEKVLRVlhRDAILAQEKSIGEDvyEKPISELDRLEEKQKETYRRMLEQLLLAEKCHR----RTVYELEN-E 201
Cdd:PTZ00121 1122 KKAEDARKAEEARKA--EDARKAEEARKAED--AKRVEIARKAEDARKAEEARKAEDAKKAEAARKaeevRKAEELRKaE 1197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 202 KHKHTDYMNKSDDFTNLLEQER-ERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQS 280
Cdd:PTZ00121 1198 DARKAEAARKAEEERKAEEARKaEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA 1277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 281 QKVQDLtqklREEEEKLKAITYKSKEDRQKllkleVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLvglsqrieel 360
Cdd:PTZ00121 1278 RKADEL----KKAEEKKKADEAKKAEEKKK-----ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA---------- 1338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 361 EETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEaqcrELKKKLQEEEHHSKELRL-- 438
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD----EAKKKAEEDKKKADELKKaa 1414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 439 ----EVEKLQKRMSELEKLEEAfsRSKSECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKD 511
Cdd:PTZ00121 1415 aakkKADEAKKKAEEKKKADEA--KKKAEEAKKADEAKKkaeEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA 1492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 512 DLTKLKSFTVMLVDERKNMMEKIK--QEERKVDGLNKnfkVEQGKVMDVTEKlIEESKKLLKLKSEMEEKVYSLTKERDE 589
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKkaEEAKKADEAKK---AEEAKKADEAKK-AEEKKKADELKKAEELKKAEEKKKAEE 1568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 590 lmgKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIREltleiERLKKRLQQLEVVEGDLM 669
Cdd:PTZ00121 1569 ---AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA-----EELKKAEEEKKKVEQLKK 1640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 670 KTEDEYDQLEQKFRTEQD---KANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRhrfRMEEAKSRDLQAEVQALKEKI 746
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEEnkiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK---EAEEAKKAEELKKKEAEEKKK 1717
|
730 740 750
....*....|....*....|....*....|..
gi 1270111431 747 HELMNKEDQLSQLQVDysvlQQRFMEEETKNK 778
Cdd:PTZ00121 1718 AEELKKAEEENKIKAE----EAKKEAEEDKKK 1745
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
156-670 |
4.12e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.96 E-value: 4.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 156 EDVYEKPISELDRLEEKQK--ETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQE 233
Cdd:PRK03918 213 SSELPELREELEKLEKEVKelEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 234 KAYQARKE--KENAKRLNKLRDELVKLKSfalmLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKL 311
Cdd:PRK03918 293 EEYIKLSEfyEEYLDELREIEKRLSRLEE----EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 312 LKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQElrdkiAKGECGN--- 388
Cdd:PRK03918 369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK-----AKGKCPVcgr 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 389 -----------SSLMAEVESLRKRVLEMEGKDEEITKTEaqcRELKKKLQEEEHHSKELRL--EVEKLQKRMSE--LEKL 453
Cdd:PRK03918 444 elteehrkellEEYTAELKRIEKELKEIEEKERKLRKEL---RELEKVLKKESELIKLKELaeQLKELEEKLKKynLEEL 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 454 EEAfSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEK 533
Cdd:PRK03918 521 EKK-AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEP 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 534 IKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEkvysLTKERDELMGKLRSEE-----ERSCELSCSV 608
Cdd:PRK03918 600 FYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE----LRKELEELEKKYSEEEyeelrEEYLELSREL 675
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 609 DLLKKRLDGIEEVEREINrgrlcKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMK 670
Cdd:PRK03918 676 AGLRAELEELEKRREEIK-----KTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKK 732
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
344-802 |
5.06e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.57 E-value: 5.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 344 RQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEIT-------KTE 416
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEelekeleSLE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 417 AQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEE------AFSRSKSECTQLHLNLEKEKNltkDLLNELEVVKS 490
Cdd:PRK03918 252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEkaeeyiKLSEFYEEYLDELREIEKRLS---RLEEEINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 491 RVKELECSESRLEKVELSLKDDLTKLKSFtvmlvDERKNMMEKIKQEERKVDGLNKNFKVEQgkvmdvTEKLIEESKKLL 570
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRLEEL-----EERHELYEEAKAKKEELERLKKRLTGLT------PEKLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 571 KLKSEMEEKVYSLTKERDELMGKlrseeerscelscsvdlLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRELTLE 650
Cdd:PRK03918 398 KAKEEIEEEISKITARIGELKKE-----------------IKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAE 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 651 IERLKKRLQQLEVVEGDLMKTEDEYDqleqKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKgEAVSQEAELrhrFRMEEA 730
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELE----KVLKKESELIKLKELAEQLKELEEKLKKYNL-EELEKKAEE---YEKLKE 532
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111431 731 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGRE-VLNLTKEL-ELSKRYSRALR 802
Cdd:PRK03918 533 KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFEsVEELEERLkELEPFYNEYLE 606
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
168-792 |
2.11e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.64 E-value: 2.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 168 RLEEKQKETYRRM------LEQL--LLAEKchRRTVYELENEKHKHTDYMNKSDDFTNL--------LEQERERLKKLLE 231
Cdd:TIGR02168 169 KYKERRKETERKLertrenLDRLedILNEL--ERQLKSLERQAEKAERYKELKAELRELelallvlrLEELREELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 232 QEKAYQaRKEKENAKRLNKLRDELVKLKSFalMLVDERQMHIEQLGLQS--QKVQDLTQKLREEEEKL-------KAITY 302
Cdd:TIGR02168 247 ELKEAE-EELEELTAELQELEEKLEELRLE--VSELEEEIEELQKELYAlaNEISRLEQQKQILRERLanlerqlEELEA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 303 KSKEDRQKLLKLEVDFEHKASRFSQ----------EHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKaee 372
Cdd:TIGR02168 324 QLEELESKLDELAEELAELEEKLEElkeelesleaELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN--- 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 373 ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKD--EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL 450
Cdd:TIGR02168 401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 451 EKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE---LEVVKSRVKELECSESRLEK-VELSLKDDLTklksftvMLVDE 526
Cdd:TIGR02168 481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNqsgLSGILGVLSELISVDEGYEAaIEAALGGRLQ-------AVVVE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 527 RKNMMEKI----KQEE--------------RKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYsLTKERD 588
Cdd:TIGR02168 554 NLNAAKKAiaflKQNElgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLD 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 589 ELMGKLRSEEERSCELSCSVDLLK----------KRLDGIEEVEREINR-GRLCKGSEftcpedNKIRELTLEIERLKKR 657
Cdd:TIGR02168 633 NALELAKKLRPGYRIVTLDGDLVRpggvitggsaKTNSSILERRREIEElEEKIEELE------EKIAELEKALAELRKE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 658 LQQLEVVEGDLMKTEDEYDQ----LEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAvSQEAELRHRFRMEEAKSR 733
Cdd:TIGR02168 707 LEELEEELEQLRKELEELSRqisaLRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE-ERLEEAEEELAEAEAEIE 785
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1270111431 734 DLQAEVQALKEKI----HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 792
Cdd:TIGR02168 786 ELEAQIEQLKEELkalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
79-773 |
1.14e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 79.33 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 79 ESEKKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTE----KTKPEVLEAHYGSAEpEKVLRVLHRDAILAQEKSI 154
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEvselEEEIEELQKELYALA-NEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 155 GEDVYEKPISELDRLEEKQKETYR---RMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLE 231
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEelaELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 232 QEKAYQARKEkENAKRLNKLRDELVKLKSFALMLVD-----ERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKE 306
Cdd:TIGR02168 394 QIASLNNEIE-RLEARLERLEDRRERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 307 DRQKLLKLEVDFEHKASRFS-----QEHEEMNAKLANQESHNRQlrlKLVGLSQRIEELEETNKSLQKA-EEELQELRDK 380
Cdd:TIGR02168 473 AEQALDAAERELAQLQARLDslerlQENLEGFSEGVKALLKNQS---GLSGILGVLSELISVDEGYEAAiEAALGGRLQA 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 381 IAKGecGNSSLMAEVESLRK----RVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL------ 450
Cdd:TIGR02168 550 VVVE--NLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlv 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 451 -EKLEEAFSRSKSecTQLHLNL------------------EKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKD 511
Cdd:TIGR02168 628 vDDLDNALELAKK--LRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 512 DLTKLKSFTVMLVDErknmmekIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELM 591
Cdd:TIGR02168 706 ELEELEEELEQLRKE-------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 592 ---GKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEdNKIRELTLEIERLKkrlQQLEVVEGDL 668
Cdd:TIGR02168 779 eaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE-RRIAATERRLEDLE---EQIEELSEDI 854
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 669 MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAknkaiekgEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHE 748
Cdd:TIGR02168 855 ESLAAEIEELEELIEELESELEALLNERASLEEALA--------LLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
|
730 740
....*....|....*....|....*
gi 1270111431 749 LmnkEDQLSQLQVDYSVLQQRFMEE 773
Cdd:TIGR02168 927 L---ELRLEGLEVRIDNLQERLSEE 948
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
219-590 |
1.28e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 79.34 E-value: 1.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 219 LEQERERLKKLLEQEKAYQARKEkenakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLK 298
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELR-----RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK---ERLEELEEDLS 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 299 AITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--------KLANQESHNRQLRLKLVGLSQRIEELE-ETNKSLQK 369
Cdd:TIGR02169 748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEEVSRIEARLREIEqKLNRLTLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 370 ---AEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLqeeehhsKELRLEVEKLQKR 446
Cdd:TIGR02169 828 keyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE---EELEELEAALRDLESRL-------GDLKKERDELEAQ 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 447 MSELEKLEEafsrsksectQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDdltklksftvmlvde 526
Cdd:TIGR02169 898 LRELERKIE----------ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS--------------- 952
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111431 527 rknmMEKIKQEERKVDglnknfkVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL 590
Cdd:TIGR02169 953 ----LEDVQAELQRVE-------EEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
344-700 |
3.17e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 77.80 E-value: 3.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 344 RQLRLKLVGLSQRIEELEETNKSLQ----KAEEELQELRDKIAKGECGNSSLMAEVESLRKrvlEMEGKDEEITKTEAQC 419
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQselrRIENRLDELSQELSDASRKIGEIEKEIEQLEQ---EEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 420 RELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRsksectqlHLNLEKEKNLTkdllNELEVVKSRVKELECSE 499
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--------RLSHSRIPEIQ----AELSKLEEEVSRIEARL 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 500 SRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvtEKLIEESKKLLKLKSEMEEK 579
Cdd:TIGR02169 815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK-----------EELEEELEELEAALRDLESR 883
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 580 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLD----GIEEVEREINR-GRLCKGSEFTCPEDNKIRELTLEIERL 654
Cdd:TIGR02169 884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSelkaKLEALEEELSEiEDPKGEDEEIPEEELSLEDVQAELQRV 963
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1270111431 655 KKRLQQLEVVEgdlMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIK 700
Cdd:TIGR02169 964 EEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
48-732 |
3.73e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.87 E-value: 3.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 48 SEDAKKNKANRKGEDDVMASGTVK----RHLKPSGESEKKTKKPLELSKEDLIQLLSIMEGElQAREDVIHMLKTEKTKP 123
Cdd:PTZ00121 1172 AEDAKKAEAARKAEEVRKAEELRKaedaRKAEAARKAEEERKAEEARKAEDAKKAEAVKKAE-EAKKDAEEAKKAEEERN 1250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 124 EVLEAHYGSAEPEKVLRvlHRDAILAQEKSIGEDVyeKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTvyelENEKH 203
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFAR--RQAAIKAEEARKADEL--KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA----DEAKK 1322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 204 KHTDYMNKSDDFTNLLEQERER--LKKLLEQEKAYQARKEKENAKRlNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQ 281
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAaeAAKAEAEAAADEAEAAEEKAEA-AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 282 KVQDLTQKLRE-EEEKLKAITYKSKEDRQKL---LKLEVDFEHKASRFSQEHEEmnAKLANQESHNRQLRLKLVGLSQRI 357
Cdd:PTZ00121 1402 EDKKKADELKKaAAAKKKADEAKKKAEEKKKadeAKKKAEEAKKADEAKKKAEE--AKKAEEAKKKAEEAKKADEAKKKA 1479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 358 EELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQE----EEHHS 433
Cdd:PTZ00121 1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADElkkaEELKK 1559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 434 KELRLEVEKLQK----RMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSL 509
Cdd:PTZ00121 1560 AEEKKKAEEAKKaeedKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK 1639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 510 KDDLTKLKSFTVMLVDERKNmmeKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESkklLKLKSEMEEKVYSLTKERDE 589
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEEN---KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA---LKKEAEEAKKAEELKKKEAE 1713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 590 LMGK---LRSEEErscELSCSVDLLKKRLdgiEEVEREINRGRLCKGseftcpEDNKIRELTLEIERLKKRL-QQLEVVE 665
Cdd:PTZ00121 1714 EKKKaeeLKKAEE---ENKIKAEEAKKEA---EEDKKKAEEAKKDEE------EKKKIAHLKKEEEKKAEEIrKEKEAVI 1781
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111431 666 GDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKS 732
Cdd:PTZ00121 1782 EEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADA 1848
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
182-849 |
4.17e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.87 E-value: 4.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 182 EQLLLAEKCHRRTVYELEnEKHKHTDYMNKSDDFTNLLEQER-ERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKS 260
Cdd:PTZ00121 1095 EAFGKAEEAKKTETGKAE-EARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE 1173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 261 FALMLVDERQMHIEQLGLQSQKVQDL--TQKLREEEEKLKAITYKSKEDRQKLLKLEvdfehKASRFSQEHEEmnAKLAN 338
Cdd:PTZ00121 1174 DAKKAEAARKAEEVRKAEELRKAEDArkAEAARKAEEERKAEEARKAEDAKKAEAVK-----KAEEAKKDAEE--AKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 339 QESHNRQLRLKLVGLSQRIEELEETNKSLQKAE-EELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTE- 416
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEe 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 417 --AQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEK---EKNLTKDLLNELEVVKSR 491
Cdd:PTZ00121 1327 akKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkaeEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 492 VKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIK---QEERKVDGLNKnfKVEQGKVMDVTEKLIEESKK 568
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKkkaEEAKKAEEAKK--KAEEAKKADEAKKKAEEAKK 1484
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 569 LLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK-----RLDGIEEVEREINRGRLCKGSEFTCPED-N 642
Cdd:PTZ00121 1485 ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeeakKADEAKKAEEKKKADELKKAEELKKAEEkK 1564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 643 KIRELTLEIERLKKRLQQLEVVEgdlmktEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELR 722
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAK------KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 723 HRFRMEEA-KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysvLQQRFMEEETKNKNMGREVLNLTKELELSKRYSRAL 801
Cdd:PTZ00121 1639 KKKEAEEKkKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 1270111431 802 RPSGNGRRMVDVpvasTGVQTEAVCGDAAEEETPAVFIRKSFQEENHI 849
Cdd:PTZ00121 1716 KKAEELKKAEEE----NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
266-618 |
1.00e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 76.26 E-value: 1.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 266 VDERQMHIEQLGLQSQKVQdltqKLREEEEKLKAITYKSKEDRQKLLKLEVDfEHKASRfsqehEEMNAKLANQESHNRQ 345
Cdd:TIGR02169 186 IERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLKEKE-ALERQK-----EAIERQLASLEEELEK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 346 LRLKLVGLSQRIEELEETNKSLQK-----AEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGK----DEEITKTE 416
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERlaklEAEIDKLL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 417 AQCRELKKKLQEEEHHSKELRLEVEKLQKRM----SELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRV 492
Cdd:TIGR02169 336 AEIEELEREIEEERKRRDKLTEEYAELKEELedlrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 493 KELECSESRLEKVELSLKDDLTKLKSftvmlvdERKNMMEKIKQEErkvdglnknfkveqGKVMDVTEKLIEESKKLLKL 572
Cdd:TIGR02169 416 QRLSEELADLNAAIAGIEAKINELEE-------EKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDL 474
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1270111431 573 KSE---MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGI 618
Cdd:TIGR02169 475 KEEydrVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
219-792 |
1.17e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.13 E-value: 1.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 219 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 298
Cdd:COG1196 205 LERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 299 AITYKSKEDRQKLLKLEVDFEH---KASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRI----EELEETNKSLQKAE 371
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARleeRRRELEERLEELEEELAELEEELEELEEELEELEEELeeaeEELEEAEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 372 EELQELRDKIAKGEcgnsslmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELE 451
Cdd:COG1196 365 EALLEAEAELAEAE-------EELEELAEELLEAL---RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 452 KLEEAfsrsksectqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMM 531
Cdd:COG1196 435 EEEEE----------EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 532 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIE-----------------------ESKKLLKLKSEMEEKVYSLTKERD 588
Cdd:COG1196 505 GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEaaleaalaaalqnivveddevaaAAIEYLKAAKAGRATFLPLDKIRA 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 589 ELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRlckgSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDL 668
Cdd:COG1196 585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR----TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 669 MKTEdeydqleqkfRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHE 748
Cdd:COG1196 661 SLTG----------GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1270111431 749 LMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMG---REVLNLTKELE 792
Cdd:COG1196 731 EAEREELLEELLEEEELLEEEALEELPEPPDLEeleRELERLEREIE 777
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
45-580 |
1.18e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 76.33 E-value: 1.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 45 KGPSEDAKKNKANRKGEDDVMASGTVKRHLKPSGESEKKTKKPLELSKEDLIQllsiMEGELQAREDVIHMLKTEKTKPE 124
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK----KKAEEAKKADEAKKKAEEAKKAE 1460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 125 VLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETyrrmlEQLLLAEKchRRTVYELEN-EKH 203
Cdd:PTZ00121 1461 EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA-----DEAKKAEE--AKKADEAKKaEEA 1533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 204 KHTDYMNKSDDFTNLLE-QERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKlksfalmlVDERQMHIEQLGLQSQK 282
Cdd:PTZ00121 1534 KKADEAKKAEEKKKADElKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK--------AEEARIEEVMKLYEEEK 1605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 283 VQDLTQKLREEEEKLKAITYKSKEDRQK----LLKLEVDFEHKASRFSQEHEEMNAKLAnqeshnrQLRLKLVGLSQRIE 358
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKkveqLKKKEAEEKKKAEELKKAEEENKIKAA-------EEAKKAEEDKKKAE 1678
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 359 ELEETNKSLQKAEEELQELRDKIAKgecgnsslmaeVESLRKRVLEMEGKDEEITKTE----AQCRELKKKLQEEEHHSK 434
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKK-----------AEELKKKEAEEKKKAEELKKAEeenkIKAEEAKKEAEEDKKKAE 1747
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 435 ELRLEVE---KLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNL------TKDLLNELEVVKSRVKELECSESRLEKV 505
Cdd:PTZ00121 1748 EAKKDEEekkKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRmevdkkIKDIFDNFANIIEGGKEGNLVINDSKEM 1827
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111431 506 ELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKlIEESKKLLKL-KSEMEEKV 580
Cdd:PTZ00121 1828 EDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEE-IEEADEIEKIdKDDIEREI 1902
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
219-711 |
1.24e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 1.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 219 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 298
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 299 AITYK------SKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEE 372
Cdd:COG1196 401 QLEELeeaeeaLLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 373 ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDE--EITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL 450
Cdd:COG1196 481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 451 EKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVkeLECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNM 530
Cdd:COG1196 561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD--LVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 531 MEKIKQEERKV----DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSC 606
Cdd:COG1196 639 AVTLAGRLREVtlegEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 607 SVDLLKKRLDGIEEVEREINRGRLCKGSE------FTCPEDNKIRELTLEIERLKKRLQQLEVVEgdlMKTEDEYDQLEQ 680
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELLEEEELleeealEELPEPPDLEELERELERLEREIEALGPVN---LLAIEEYEELEE 795
|
490 500 510
....*....|....*....|....*....|..
gi 1270111431 681 KFrteqdkaNFLSQQLEEIKHQMAK-NKAIEK 711
Cdd:COG1196 796 RY-------DFLSEQREDLEEARETlEEAIEE 820
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
228-792 |
1.43e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 75.44 E-value: 1.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 228 KLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfaLMLVDERQMH-----IEQLGLQSQKVQDLTQKLREEEEKLKAITY 302
Cdd:TIGR04523 78 KILEQQIKDLNDKLKKNKDKINKLNSDLSKINS--EIKNDKEQKNkleveLNKLEKQKKENKKNIDKFLTEIKKKEKELE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 303 KSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVglsqRIEELEETNKSLQKAEEELQELrdkia 382
Cdd:TIGR04523 156 KLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLESQISELKKQ----- 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 383 kgecgNSSLMAEVESLRKrvlEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLeeaFSRSKS 462
Cdd:TIGR04523 227 -----NNQLKDNIEKKQQ---EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQ---LNQLKS 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 463 ECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 542
Cdd:TIGR04523 296 EI--SDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 543 GLNKNfkveqgkvmdvTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVE 622
Cdd:TIGR04523 374 KLKKE-----------NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET---IIKNN 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 623 REInrgrlckgSEFTcpedNKIRELTLEIERLKKRL----QQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 698
Cdd:TIGR04523 440 SEI--------KDLT----NQDSVKELIIKNLDNTResleTQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 699 IKHQMaKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIH------ELMNKEDQLSQLQVDYSVLQQRFME 772
Cdd:TIGR04523 508 LEEKV-KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkenlekEIDEKNKEIEELKQTQKSLKKKQEE 586
|
570 580
....*....|....*....|
gi 1270111431 773 EETKNKNMGREVLNLTKELE 792
Cdd:TIGR04523 587 KQELIDQKEKEKKDLIKEIE 606
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
217-753 |
3.01e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 74.29 E-value: 3.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 217 NLLEQERERLKKLLEQEKAYQA------RKEKENAKRLNKLRDELVKLKsfaLMLVDERQMHIEQLGLQSQKVQDLTQKL 290
Cdd:TIGR04523 120 NKLEVELNKLEKQKKENKKNIDkflteiKKKEKELEKLNNKYNDLKKQK---EELENELNLLEKEKLNIQKNIDKIKNKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 291 REEEEKLKAItyKSKEDRQKLLKLEV-DFEHKASRF-------SQEHEEMNAKLANQESHNRQLRLKLVG----LSQRIE 358
Cdd:TIGR04523 197 LKLELLLSNL--KKKIQKNKSLESQIsELKKQNNQLkdniekkQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQK 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 359 ELEETNKSLQKAEEELQELRDKIA-----KGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHS 433
Cdd:TIGR04523 275 ELEQNNKKIKELEKQLNQLKSEISdlnnqKEQDWNKELKSELKNQEKKLEEIQ---NQISQNNKIISQLNEQISQLKKEL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 434 KELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNltkDLLNELEVVKSRVKELECSESRLEKVELSLKDDL 513
Cdd:TIGR04523 352 TNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIN---DLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 514 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvyslTKERDELMGK 593
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK----EKELKKLNEE 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 594 LRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRE-LTLEIERLKKRLQQLEVVEGDLMKTE 672
Cdd:TIGR04523 505 KKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEnLEKEIDEKNKEIEELKQTQKSLKKKQ 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 673 DEYDQLEQKFrtEQDKANFLSQQLEEIKHQMAKNKAIEKGEAvsQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNK 752
Cdd:TIGR04523 585 EEKQELIDQK--EKEKKDLIKEIEEKEKKISSLEKELEKAKK--ENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
|
.
gi 1270111431 753 E 753
Cdd:TIGR04523 661 W 661
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
353-743 |
8.47e-13 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 72.88 E-value: 8.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 353 LSQRIEELEETNKSLQKAEEELQELRDKIAKgecgnssLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHH 432
Cdd:COG4717 76 LEEELKEAEEKEEEYAELQEELEELEEELEE-------LEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPER 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 433 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQL--HLNLEKEKNLtKDLLNELEVVKSRVKELecsESRLEKVELSLK 510
Cdd:COG4717 148 LEELEERLEELRELEEELEELEAELAELQEELEELleQLSLATEEEL-QDLAEELEELQQRLAEL---EEELEEAQEELE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 511 DDLTKLKSFTVMLVDERKNmmEKIKQEERK---------VDGLNKNFKVEQGKVMDV------------------TEKLI 563
Cdd:COG4717 224 ELEEELEQLENELEAAALE--ERLKEARLLlliaaallaLLGLGGSLLSLILTIAGVlflvlgllallflllareKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 564 EESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREI-------NRGRLCKGSEF 636
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqleeleqEIAALLAEAGV 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 637 TCPED--------NKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEyDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKA 708
Cdd:COG4717 382 EDEEElraaleqaEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELEA 460
|
410 420 430
....*....|....*....|....*....|....*.
gi 1270111431 709 -IEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALK 743
Cdd:COG4717 461 eLEQLEEDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
167-814 |
1.05e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 72.84 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 167 DRLEEKQKETYRRMleQLLLAEKCHR--RTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 244
Cdd:pfam15921 245 DQLEALKSESQNKI--ELLLQQHQDRieQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 245 AKRLNKLRDELVKLKSfalMLVDERQMHIEQLGLQSQkvqDLTQKLREEEEklkaITYKSKEDRQKLLKLEVDFEHKASR 324
Cdd:pfam15921 323 ESTVSQLRSELREAKR---MYEDKIEELEKQLVLANS---ELTEARTERDQ----FSQESGNLDDQLQKLLADLHKREKE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 325 FSQEHEEmNAKLANQESHNR----QLRLKLVGLSQRIEELEETNKSLQ-----KAEEELQELRDKIAKGEcGNSSLMAEV 395
Cdd:pfam15921 393 LSLEKEQ-NKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKsecqgQMERQMAAIQGKNESLE-KVSSLTAQL 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 396 ES----LRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR----MSELEKL---EEAFSRSKSEC 464
Cdd:pfam15921 471 EStkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlkLQELQHLkneGDHLRNVQTEC 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 465 TQLHLNLEKEKNLTKDLLNELEVVKSRVKE-------LECSESRLEKvelSLKDDLTKLKSFTVMlvDERKNmmEKIKQE 537
Cdd:pfam15921 551 EALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQLEK---EINDRRLELQEFKIL--KDKKD--AKIREL 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 538 ERKVDGLNKnfkveqgkvmdvteklieESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRL-D 616
Cdd:pfam15921 624 EARVSDLEL------------------EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFrN 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 617 GIEEVEREINRGRLckgseftcpednKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQL 696
Cdd:pfam15921 686 KSEEMETTTNKLKM------------QLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFL 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 697 EEIKHQMAKNKAIEKGE--AVSQEAELRHRFRMEEAKSRD-LQAEVQALKEKIhelMNKEDQLSQLQVDYSVLQQRFMEE 773
Cdd:pfam15921 754 EEAMTNANKEKHFLKEEknKLSQELSTVATEKNKMAGELEvLRSQERRLKEKV---ANMEVALDKASLQFAECQDIIQRQ 830
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 1270111431 774 ETKNKNMGREVLNLTKELE------LSKRYSRALRPSGNGRRMVDVP 814
Cdd:pfam15921 831 EQESVRLKLQHTLDVKELQgpgytsNSSMKPRLLQPASFTRTHSNVP 877
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
143-802 |
2.43e-12 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 71.68 E-value: 2.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 143 HRDAILAQEKSIGEDVYEKPISELdRLEEKQKETYRRMLEQL-------LLAEKCHRR----TVYELENEKHKHTdYMNK 211
Cdd:pfam05483 111 NRKIIEAQRKAIQELQFENEKVSL-KLEEEIQENKDLIKENNatrhlcnLLKETCARSaektKKYEYEREETRQV-YMDL 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 212 SDDFTNLLeQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfalmlVDERQMHIEQLGLQS----QKVQDLT 287
Cdd:pfam05483 189 NNNIEKMI-LAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE-------INDKEKQVSLLLIQItekeNKMKDLT 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 288 QKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSL 367
Cdd:pfam05483 261 FLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEEL 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 368 QKAEEELQELRDKIAKGECGNSSLM-AEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL---EVEKL 443
Cdd:pfam05483 341 NKAKAAHSFVVTEFEATTCSLEELLrTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKilaEDEKL 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 444 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEknlTKDLLNELEVVKS-------RVKEL--ECSESRLEKVELSLKDDLT 514
Cdd:pfam05483 421 LDEKKQFEKIAEELKGKEQELIFLLQAREKE---IHDLEIQLTAIKTseehylkEVEDLktELEKEKLKNIELTAHCDKL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 515 KLKSFTvmLVDERKNMMEKIKQEERKVDglnkNFKVEQGKVMDVTEKLIEeskKLLKLKSEMEEKVYSLTKERDELMGKL 594
Cdd:pfam05483 498 LLENKE--LTQEASDMTLELKKHQEDII----NCKKQEERMLKQIENLEE---KEMNLRDELESVREEFIQKGDEVKCKL 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 595 RSEEERSCELSCSVDLLKKRLDGIEEVereinrgrlCKGSEFTCPEDNK-IRELTLEIERLKKR----LQQLEVVEGDLM 669
Cdd:pfam05483 569 DKSEENARSIEYEVLKKEKQMKILENK---------CNNLKKQIENKNKnIEELHQENKALKKKgsaeNKQLNAYEIKVN 639
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 670 KTEDEYDQLEQKF----RTEQDKANFLSQQLEEIKHQMAKNKAIEKgEAVSQEAELRHRFRMEeaksrdlQAEVQALKEK 745
Cdd:pfam05483 640 KLELELASAKQKFeeiiDNYQKEIEDKKISEEKLLEEVEKAKAIAD-EAVKLQKEIDKRCQHK-------IAEMVALMEK 711
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 746 IHELMNK--EDQLSQLQVDYSVLQQRFMEE---ETKNKNMGREVLNLTKELELSKRYSRALR 802
Cdd:pfam05483 712 HKHQYDKiiEERDSELGLYKNKEQEQSSAKaalEIELSNIKAELLSLKKQLEIEKEEKEKLK 773
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
209-627 |
1.71e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.93 E-value: 1.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 209 MNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKsfalmlvderqmhieqlglqsqkvQDLTQ 288
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE------------------------EELEQ 716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 289 KLREEEEKLKAITyKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETnksLQ 368
Cdd:TIGR02168 717 LRKELEELSRQIS-ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ---IE 792
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 369 KAEEELQELRDKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEehhSKELRLEVEKLQKRMS 448
Cdd:TIGR02168 793 QLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ---IEELSEDIESLAAEIE 862
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 449 ELEKLEEAfsrsksectqlhlnLEKEknlTKDLLNELEVVKSRVKELecsESRLEKVELSLKDDLTKLKSftvmLVDERK 528
Cdd:TIGR02168 863 ELEELIEE--------------LESE---LEALLNERASLEEALALL---RSELEELSEELRELESKRSE----LRRELE 918
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 529 NMMEKIKQEERKVDGLNKNFKVEQGKVM----DVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL-------MGKLRSE 597
Cdd:TIGR02168 919 ELREKLAQLELRLEGLEVRIDNLQERLSeeysLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEEL 998
|
410 420 430
....*....|....*....|....*....|
gi 1270111431 598 EERSCELSCSVDLLKKRLDGIEEVEREINR 627
Cdd:TIGR02168 999 KERYDFLTAQKEDLTEAKETLEEAIEEIDR 1028
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
218-775 |
2.64e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 68.14 E-value: 2.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 218 LLEQERERLKKLLEQekaYQARKEKENAKRLNKLRDELVKLKS------------------FALMLVD--ERQMHIEQLG 277
Cdd:PRK02224 181 VLSDQRGSLDQLKAQ---IEEKEEKDLHERLNGLESELAELDEeieryeeqreqaretrdeADEVLEEheERREELETLE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 278 lqsQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEH----------KASRFSQEHEEMNAKLANQESHNRQLR 347
Cdd:PRK02224 258 ---AEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDllaeaglddaDAEAVEARREELEDRDEELRDRLEECR 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 348 LKLV-------GLSQRIEELEETNKSLQKA----EEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTE 416
Cdd:PRK02224 335 VAAQahneeaeSLREDADDLEERAEELREEaaelESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 417 AQCRELKKKLQEEEhhsKELRLEVEKLQKRMSELEKLEEAfsrSK-SECTQlhlNLEKEknltkdllnelevvkSRVKEL 495
Cdd:PRK02224 415 EELREERDELRERE---AELEATLRTARERVEEAEALLEA---GKcPECGQ---PVEGS---------------PHVETI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 496 ECSESRLEKVELSLKDDLTKLKSftvmlVDERKNMMEKIKQEERKVDGLNKNfkveqgkvMDVTEKLIEESKKLLKlksE 575
Cdd:PRK02224 471 EEDRERVEELEAELEDLEEEVEE-----VEERLERAEDLVEAEDRIERLEER--------REDLEELIAERRETIE---E 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 576 MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREIN--RGRLCKGSEftcpEDNKIRELTLEIER 653
Cdd:PRK02224 535 KRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKerIESLERIRT----LLAAIADAEDEIER 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 654 LKKRLQQLEVVEgdlmktedeyDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKaieKGEAVSQEAELRHRFRMEEAKSR 733
Cdd:PRK02224 611 LREKREALAELN----------DERRERLAEKRERKRELEAEFDEARIEEARED---KERAEEYLEQVEEKLDELREERD 677
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1270111431 734 DLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEET 775
Cdd:PRK02224 678 DLQAEIGAVENELEELEELRERREALENRVEALEALYDEAEE 719
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
196-795 |
3.37e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 68.07 E-value: 3.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 196 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKlleqekayQARKEKENAKRLNKLRDELVKLKsfalmLVDERQMHIEQ 275
Cdd:pfam02463 172 KEALKKLIEETENLAELIIDLEELKLQELKLKE--------QAKKALEYYQLKEKLELEEEYLL-----YLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 276 LglqsQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQ 355
Cdd:pfam02463 239 I----DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 356 RIEELEETNKSLQKAEEELQELRDKIAKgecgnsslmaEVESLRKRVLEMEgkdeeiTKTEAQCRELKKKLQEEEHHSKE 435
Cdd:pfam02463 315 KLKESEKEKKKAEKELKKEKEEIEELEK----------ELKELEIKREAEE------EEEEELEKLQEKLEQLEEELLAK 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 436 LRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLN-ELEVVKSRVKELECSESRLEKVELSLKDDLT 514
Cdd:pfam02463 379 KKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKeELEILEEEEESIELKQGKLTEEKEELEKQEL 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 515 KLKSFTVMLVDERKNMMEKIKQEERkvdgLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKL 594
Cdd:pfam02463 459 KLLKDELELKKSEDLLKETQLVKLQ----EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDL 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 595 RSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLckgsEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDE 674
Cdd:pfam02463 535 GVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL----TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 675 YDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAEL---RHRFRMEEAKSRDLQAEVQALKEKIHELMN 751
Cdd:pfam02463 611 ATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGlaeKSEVKASLSELTKELLEIQELQEKAESELA 690
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1270111431 752 KEDQLSQLQvDYSVLQQRFMEEETKNKNMGREVLNLTKELELSK 795
Cdd:pfam02463 691 KEEILRRQL-EIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
420-796 |
3.82e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.79 E-value: 3.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 420 RELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLtkdLLNELEVVKSRVKELECSE 499
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 500 SRLEKVELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLnknfkvEQGKVMDVTEKLIEESKKLLKLKSEMEEK 579
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEA-------RIEELEEDLHKLEEALNDL------EARLSHSRIPEIQAELSKLEEEVSRIEAR 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 580 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVEREINRGRLckgseftcpednKIRELTLEIERLKKRLQ 659
Cdd:TIGR02169 814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ---IKSIEKEIENLNG------------KKEELEEELEELEAALR 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 660 QLEVVEGDLMKtedEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAiEKGEAVSQEAELRHRFRM------EEAKSR 733
Cdd:TIGR02169 879 DLESRLGDLKK---ERDELEAQLRELERKIEELEAQIEKKRKRLSELKA-KLEALEEELSEIEDPKGEdeeipeEELSLE 954
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111431 734 DLQAEVQALKEKIHEL----MNKEDQLSQLQVDYSVLQQRFMEEETKNKnmgrEVLNLTKELELSKR 796
Cdd:TIGR02169 955 DVQAELQRVEEEIRALepvnMLAIQEYEEVLKRLDELKEKRAKLEEERK----AILERIEEYEKKKR 1017
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
410-756 |
5.70e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.39 E-value: 5.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 410 EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVvk 489
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA-- 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 490 srvkELECSESRLEKVELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLieeskkl 569
Cdd:TIGR02168 762 ----EIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL------- 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 570 lklkSEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRGRLckgseftcpednKIRELTL 649
Cdd:TIGR02168 827 ----ESLERRIAATERRLEDLEEQIEELSED-----------------IESLAAEIEELEE------------LIEELES 873
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 650 EIERLKKRLQQLEVvegDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAiEKGEAVSQEAELRHRFRME- 728
Cdd:TIGR02168 874 ELEALLNERASLEE---ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-RLEGLEVRIDNLQERLSEEy 949
|
330 340 350
....*....|....*....|....*....|....*
gi 1270111431 729 -------EAKSRDLQAEVQALKEKIHELMNKEDQL 756
Cdd:TIGR02168 950 sltleeaEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
168-795 |
6.31e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 66.99 E-value: 6.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 168 RLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERE----RLKKLLEQEKAYQARKEKE 243
Cdd:TIGR00606 287 ELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTellvEQGRLQLQADRHQEHIRAR 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 244 NAKRL-NKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKA 322
Cdd:TIGR00606 367 DSLIQsLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKK 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 323 SRFSQEHEEMNAKLANQEshnrqlrlKLVGLSQRIEELEEtnkSLQKAEEELQELRDKiakgecgnsslmAEVESLRKRV 402
Cdd:TIGR00606 447 EILEKKQEELKFVIKELQ--------QLEGSSDRILELDQ---ELRKAERELSKAEKN------------SLTETLKKEV 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 403 LEMEGKDEEITKTEaqcRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECT----------QLHLNLE 472
Cdd:TIGR00606 504 KSLQNEKADLDRKL---RKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTsllgyfpnkkQLEDWLH 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 473 KEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKL--KSFTVMLVDERKNMMEKIKQEERKV--------- 541
Cdd:TIGR00606 581 SKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYedKLFDVCGSQDEESDLERLKEEIEKSskqramlag 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 542 -----DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELscsVDLLKKRLD 616
Cdd:TIGR00606 661 atavySQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEM---LGLAPGRQS 737
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 617 GIEEVEREINRGRlckgseftcpedNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQL 696
Cdd:TIGR00606 738 IIDLKEKEIPELR------------NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVE 805
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 697 EEIKHQMAKNKAIEKGEAVSQ----EAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 772
Cdd:TIGR00606 806 RKIAQQAAKLQGSDLDRTVQQvnqeKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ 885
|
650 660
....*....|....*....|...
gi 1270111431 773 EETKNKNMGREVLNLTKELELSK 795
Cdd:TIGR00606 886 FEEQLVELSTEVQSLIREIKDAK 908
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
77-467 |
1.55e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 1.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 77 SGESEKKTKKPLELSKE--DLIQLLSIMEGELQAREDVIHMLKTEKTkpevleahygsaEPEKVLRVLHRDAILAQEKSI 154
Cdd:TIGR02168 662 TGGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELE------------ELEEELEQLRKELEELSRQIS 729
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 155 GEDvyekpiSELDRLEEKQkETYRRMLEQLllaekchRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQek 234
Cdd:TIGR02168 730 ALR------KDLARLEAEV-EQLEERIAQL-------SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ-- 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 235 ayQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEklkaitykskedrqKLLKL 314
Cdd:TIGR02168 794 --LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE--------------DIESL 857
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 315 EVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAE 394
Cdd:TIGR02168 858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 395 VESLRKRVLE------------MEGKDEEITKTEAQCRELKKKLQE---------EEHHSKELRLEVEKLQKR--MSELE 451
Cdd:TIGR02168 938 IDNLQERLSEeysltleeaealENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDFLTAQKEdlTEAKE 1017
|
410
....*....|....*.
gi 1270111431 452 KLEEAFSRSKSECTQL 467
Cdd:TIGR02168 1018 TLEEAIEEIDREARER 1033
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
136-763 |
3.64e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 64.55 E-value: 3.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 136 EKVLRVLHRDAILAQEKSIGEDVY----EKP--ISELDRLEEkQKETYRRMLEQLLLAEKCHRRtvyeLENEKHKHTDYM 209
Cdd:COG4913 191 EKALRLLHKTQSFKPIGDLDDFVReymlEEPdtFEAADALVE-HFDDLERAHEALEDAREQIEL----LEPIRELAERYA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 210 NKSDDFtNLLEQERERLKKLLEQEKAYQARKEKENAKR-LNKLRDELVKLKS-FALMLVDERQMHIEQLGLQSQKVQDLT 287
Cdd:COG4913 266 AARERL-AELEYLRAALRLWFAQRRLELLEAELEELRAeLARLEAELERLEArLDALREELDELEAQIRGNGGDRLEQLE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 288 QKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRlklvglsqriEELEETNKSL 367
Cdd:COG4913 345 REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE----------EALAEAEAAL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 368 QKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLemegkdEEITKTEAQCR---ELKKKLQEEEH---------HSKE 435
Cdd:COG4913 415 RDLRRELRELEAEIASLERRKSNIPARLLALRDALA------EALGLDEAELPfvgELIEVRPEEERwrgaiervlGGFA 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 436 LRLEVEklqkrmselEKLEEAFSRS-KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE---KVELSlkd 511
Cdd:COG4913 489 LTLLVP---------PEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRawlEAELG--- 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 512 dltklKSFTVMLVDERknmmEKIKQEERKV--DGL----------NKNFKVEQGKVM--DVTEKLIEESKKLLKLKSEME 577
Cdd:COG4913 557 -----RRFDYVCVDSP----EELRRHPRAItrAGQvkgngtrhekDDRRRIRSRYVLgfDNRAKLAALEAELAELEEELA 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 578 EkvysLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDgIEEVEREINRGRlckgseftcpedNKIRELTL---EIERL 654
Cdd:COG4913 628 E----AEERLEALEAELDALQERREALQRLAEYSWDEID-VASAEREIAELE------------AELERLDAssdDLAAL 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 655 KKRLQQLEVVEGDLmktEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAknkAIEKGEAVSQEAELRHRF------RME 728
Cdd:COG4913 691 EEQLEELEAELEEL---EEELDELKGEIGRLEKELEQAEEELDELQDRLE---AAEDLARLELRALLEERFaaalgdAVE 764
|
650 660 670
....*....|....*....|....*....|....*
gi 1270111431 729 EAKSRDLQAEVQALKEKIHelmNKEDQLSQLQVDY 763
Cdd:COG4913 765 RELRENLEERIDALRARLN---RAEEELERAMRAF 796
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
197-792 |
3.87e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 64.43 E-value: 3.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 197 ELENEKHKHTDYMNKSDDFTNLLEQERerlKKLLEQEKAYQARKEKENAKRlNKLRDELV----KLKSFA---LMLVDER 269
Cdd:pfam01576 72 ELEEILHELESRLEEEEERSQQLQNEK---KKMQQHIQDLEEQLDEEEAAR-QKLQLEKVtteaKIKKLEediLLLEDQN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 270 QMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLK 349
Cdd:pfam01576 148 SKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLK-KEEKGRQELEKAKRKL---EGESTDLQEQ 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 350 LVGLSQRIEELEetnKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLE----MEGKDEEITKTEAQCRELKKK 425
Cdd:pfam01576 224 IAELQAQIAELR---AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISElqedLESERAARNKAEKQRRDLGEE 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 426 LQ----EEEHHSKELRLEVEKLQKRMSELEKLEEAF-SRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSES 500
Cdd:pfam01576 301 LEalktELEDTLDTTAAQQELRSKREQEVTELKKALeEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 501 RLEKVELSLKDDLTKLKSftvmlvderknmmekikqeeRKVDGLNKNFKVEqGKVMDVTEKLIEESKKllklKSEMEEKV 580
Cdd:pfam01576 381 ALESENAELQAELRTLQQ--------------------AKQDSEHKRKKLE-GQLQELQARLSESERQ----RAELAEKL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 581 YSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPED--NKIRELTLEIERLKKRL 658
Cdd:pfam01576 436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDerNSLQEQLEEEEEAKRNV 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 659 Q-QLEVVEGDLM----KTEDE---YDQLEQKFRTEQDKANFLSQQLEEikhqmaKNKAIEKGEavsqeaelRHRFRMEEa 730
Cdd:pfam01576 516 ErQLSTLQAQLSdmkkKLEEDagtLEALEEGKKRLQRELEALTQQLEE------KAAAYDKLE--------KTKNRLQQ- 580
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111431 731 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGRE----VLNLTKELE 792
Cdd:pfam01576 581 ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREketrALSLARALE 646
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
252-792 |
1.13e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 62.84 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 252 RDELVKLKSFALMLVDE-RQMHIEQ---LGLQSQKVQDLTQKLREEEEKLKAItykskedrQKLLKLEVDFEHKASRFSQ 327
Cdd:pfam05557 1 RAELIESKARLSQLQNEkKQMELEHkraRIELEKKASALKRQLDRESDRNQEL--------QKRIRLLEKREAEAEEALR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 328 EHEEMN-AKLANQESHNRQLRLKlvglSQRIEELEETNKSLQKaeeELQELRDKIAKGECGNSSLMAEVESLRKR----- 401
Cdd:pfam05557 73 EQAELNrLKKKYLEALNKKLNEK----ESQLADAREVISCLKN---ELSELRRQIQRAELELQSTNSELEELQERldllk 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 402 ---------VLEMEGKDEEITKTEAQCRELKKKLQEEEHHS---KELRLEVEKLQKRMSELEKLEE--AFSRSKSECTQL 467
Cdd:pfam05557 146 akaseaeqlRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSeivKNSKSELARIPELEKELERLREhnKHLNENIENKLL 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 468 hlnLEKEKNLTKDLLNELEVVKSRVKELECSESRLE-------KVELSLKDDLTK---LKSFTVMLVDERKNMMEKIKQE 537
Cdd:pfam05557 226 ---LKEEVEDLKRKLEREEKYREEAATLELEKEKLEqelqswvKLAQDTGLNLRSpedLSRRIEQLQQREIVLKEENSSL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 538 ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS---EMEEKVYSLTKERDELMGKLRS------EEERSCELSCSV 608
Cdd:pfam05557 303 TSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKAlvrRLQRRVLLLTKERDGYRAILESydkeltMSNYSPQLLERI 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 609 DLLKKRLDGIEEVEREInRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVvegdlMKTEDEYDQLEQKFRTEQDK 688
Cdd:pfam05557 383 EEAEDMTQKMQAHNEEM-EAQLSVAEEELGGYKQQAQTLERELQALRQQESLADP-----SYSKEEVDSLRRKLETLELE 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 689 ANFLSQQLEEIKHQMA-----------KNKAIEKGEAVSQEAELRHRFRMEEaksrdLQAEVQALKEKIHELMNKEDQLS 757
Cdd:pfam05557 457 RQRLREQKNELEMELErrclqgdydpkKTKVLHLSMNPAAEAYQQRKNQLEK-----LQAEIERLKRLLKKLEDDLEQVL 531
|
570 580 590
....*....|....*....|....*....|....*
gi 1270111431 758 QLQvdysvlqqrfmeeETKNKNMGREVLNLTKELE 792
Cdd:pfam05557 532 RLP-------------ETTSTMNFKEVLDLRKELE 553
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
82-537 |
3.05e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 61.62 E-value: 3.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 82 KKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPekvlRVLHRDAILAQEKSIGEDVYEK 161
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEE----RHELYEEAKAKKEELERLKKRL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 162 PISELDRLEEKQKETYRRMLEqLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTN--------LLEQERERLKKLLEQE 233
Cdd:PRK03918 382 TGLTPEKLEKELEELEKAKEE-IEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpvcgreLTEEHRKELLEEYTAE 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 234 KAYQARKEKENAKRLNKLRDELVKLKSFalmLVDERQMhieqlglqsQKVQDLTQKLREEEEKLKAITYKskedrqkllk 313
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKV---LKKESEL---------IKLKELAEQLKELEEKLKKYNLE---------- 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 314 levdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIakGECGNSSL-- 391
Cdd:PRK03918 519 -------ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL--EELGFESVee 589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 392 ----MAEVESLRKRVL-------EMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMS--ELEKLEEAFS 458
Cdd:PRK03918 590 leerLKELEPFYNEYLelkdaekELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSeeEYEELREEYL 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 459 RSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDD---LTKLKSFTVMLVDERKNMMEKIK 535
Cdd:PRK03918 670 ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVeelREKVKKYKALLKERALSKVGEIA 749
|
..
gi 1270111431 536 QE 537
Cdd:PRK03918 750 SE 751
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
71-603 |
5.38e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 60.76 E-value: 5.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 71 KRHLKPSGESEKKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQ 150
Cdd:pfam02463 470 SEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 151 EKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE-------KHKHTDYMNKSDDFTNLLEQER 223
Cdd:pfam02463 550 IVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDpilnlaqLDKATLEADEDDKRAKVVEGIL 629
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 224 ERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYK 303
Cdd:pfam02463 630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 304 SKEDRQKLLKLEVdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNK--SLQKAEEELQELRDKI 381
Cdd:pfam02463 710 EELKKLKLEAEEL----LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSelSLKEKELAEEREKTEK 785
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 382 AKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSK 461
Cdd:pfam02463 786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITK 865
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 462 SECTQlHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKV--------------ELSLKDDLTKLKSFTVMLVDER 527
Cdd:pfam02463 866 EELLQ-ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlnlleekeneieerIKEEAEILLKYEEEPEELLLEE 944
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 528 KN----MMEKIKQEERKVDGLNKNFKVEqgkvMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCE 603
Cdd:pfam02463 945 ADekekEENNKEEEEERNKRLLLAKEEL----GKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
204-601 |
5.72e-09 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 60.86 E-value: 5.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 204 KHTDYMNKSDDFTNL-----LEQERERLKKLLE-----QEKAYQARKEKENAKRLNKLRDELVKLKsFALMLVDERQMHI 273
Cdd:COG5022 785 RLVDYELKWRLFIKLqpllsLLGSRKEYRSYLAciiklQKTIKREKKLRETEEVEFSLKAEVLIQK-FGRSLKAKKRFSL 863
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 274 EQ---LGLQSQ-KVQDLTQKLREEEEKLKAITY---KSKEDRQKLLKLEVDFEhkaSRFSQEHEEMNAKLANQESHNRQL 346
Cdd:COG5022 864 LKketIYLQSAqRVELAERQLQELKIDVKSISSlklVNLELESEIIELKKSLS---SDLIENLEFKTELIARLKKLLNNI 940
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 347 RLKlvglSQRIEELEEtNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTeaqcRELKKKL 426
Cdd:COG5022 941 DLE----EGPSIEYVK-LPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAEL----SKQYGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 427 QEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNeLEVVKSRVKELECSESRLEKVE 506
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKA-LKLRRENSLLDDKQLYQLESTE 1090
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 507 lslkddlTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvteKLIEESKKLLKLKS---EMEEKVYSL 583
Cdd:COG5022 1091 -------NLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKL------------NLLQEISKFLSQLVntlEPVFQKLSV 1151
|
410
....*....|....*...
gi 1270111431 584 TKERDELMGKLRSEEERS 601
Cdd:COG5022 1152 LQLELDGLFWEANLEALP 1169
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
358-579 |
1.41e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 358 EELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELR 437
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 438 LEVEKLQKRMSELekLEEAFSRSKSECTQLHLNLEKEKNLTKDL--LNEL-EVVKSRVKELECSESRLEKVELSLKDDLT 514
Cdd:COG4942 97 AELEAQKEELAEL--LRALYRLGRQPPLALLLSPEDFLDAVRRLqyLKYLaPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111431 515 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVmdvtEKLIEESKKLLKLKSEMEEK 579
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL----AELQQEAEELEALIARLEAE 235
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
164-684 |
1.51e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 59.28 E-value: 1.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 164 SELDRLEEkQKETYRRMLEQLLLAEKCHRRTVYELENekhkhtdymnksddftnlLEQERERLkklleQEKAYQARKEKE 243
Cdd:PRK02224 220 EEIERYEE-QREQARETRDEADEVLEEHEERREELET------------------LEAEIEDL-----RETIAETERERE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 244 NAK-RLNKLRDELVKLKSFALMLVDERQM---HIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFE 319
Cdd:PRK02224 276 ELAeEVRDLRERLEELEEERDDLLAEAGLddaDAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 320 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEE----TNKSLQKAEEELQELRDKIAKGECGNSSLMAEV 395
Cdd:PRK02224 356 ERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdAPVDLGNAEDFLEELREERDELREREAELEATL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 396 ESLRKRVLEME-----GK---------DEEITKTEAQCRELKKKLQEEEhhsKELRLEVEKLQKRMSELEKLEEAFSRsk 461
Cdd:PRK02224 436 RTARERVEEAEalleaGKcpecgqpveGSPHVETIEEDRERVEELEAEL---EDLEEEVEEVEERLERAEDLVEAEDR-- 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 462 sectqlhlnLEKEKNLTKDLLNELEVVKSRV--KELECSESRLEKVELSLKDDLTKlksftvmlvDERKNMMEKIKQEER 539
Cdd:PRK02224 511 ---------IERLEERREDLEELIAERRETIeeKRERAEELRERAAELEAEAEEKR---------EAAAEAEEEAEEARE 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 540 KVDGLNKnfkvEQGKVMDVTEKLiEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDG-- 617
Cdd:PRK02224 573 EVAELNS----KLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEar 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 618 IEEVereinRGRLCKGSEFTCPEDNKIRELTL-----------------EIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ 680
Cdd:PRK02224 648 IEEA-----REDKERAEEYLEQVEEKLDELREerddlqaeigaveneleELEELRERREALENRVEALEALYDEAEELES 722
|
....
gi 1270111431 681 KFRT 684
Cdd:PRK02224 723 MYGD 726
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
237-459 |
2.50e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 2.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 237 QARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEV 316
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 317 DFEHKASRFSQ---------EHEEMNAKLANQESHNRQLRLKLVG-----LSQRIEELEETNKSLQKAEEELQELRDKIA 382
Cdd:COG4942 98 ELEAQKEELAEllralyrlgRQPPLALLLSPEDFLDAVRRLQYLKylapaRREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111431 383 KgecgnssLMAEVESLRKRVlemegkDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSR 459
Cdd:COG4942 178 A-------LLAELEEERAAL------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
289-790 |
3.76e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 57.72 E-value: 3.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 289 KLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNaKLANQEShnrQLRLKLVGLSQRIEELeetNKSLQ 368
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIK-ILEQQIK---DLNDKLKKNKDKINKL---NSDLS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 369 KAEEELQELRDKIAKGEcgnsslmAEVESLRKrvlemegkdeEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMS 448
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLE-------VELNKLEK----------QKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 449 ELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERK 528
Cdd:TIGR04523 170 ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 529 NMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEME----EKVYSLTKE-RDELMGKLRSEEERSCE 603
Cdd:TIGR04523 250 NTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKElKSELKNQEKKLEEIQNQ 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 604 LSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPED--NKIRELTLEIERLKKRLQQLEV----VEGDLMKTEDEYDQ 677
Cdd:TIGR04523 330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEkqNEIEKLKKENQSYKQEIKNLESqindLESKIQNQEKLNQQ 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 678 LEQKFRTEQDKANFLSQQLEEIKHQMAKNKAiEKGEAVSQEAELRHRFRMEEAKSRDLQAEV-----------QALKEKI 746
Cdd:TIGR04523 410 KDEQIKKLQQEKELLEKEIERLKETIIKNNS-EIKDLTNQDSVKELIIKNLDNTRESLETQLkvlsrsinkikQNLEQKQ 488
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1270111431 747 HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKE 790
Cdd:TIGR04523 489 KELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE 532
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
196-799 |
7.04e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.05 E-value: 7.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 196 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKLleQEKAYQARKEKENAKRLnkLRDELVKLKSFALMLVDERQMHIEQ 275
Cdd:pfam15921 57 YEVELDSPRKIIAYPGKEHIERVLEEYSHQVKDL--QRRLNESNELHEKQKFY--LRQSVIDLQTKLQEMQMERDAMADI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 276 LGLQSQKVQDLTQKLREEEEKLKAiTYKSKEDR----------------------QKLLKLEVDFEHKASRFSQEHEEMN 333
Cdd:pfam15921 133 RRRESQSQEDLRNQLQNTVHELEA-AKCLKEDMledsntqieqlrkmmlshegvlQEIRSILVDFEEASGKKIYEHDSMS 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 334 A----KLANQESHN-RQLRLKLVGLSQRIEELEETNKSLQ-----KAEEELQELRDK----IAKGECGNSSLMAEVESLR 399
Cdd:pfam15921 212 TmhfrSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKsesqnKIELLLQQHQDRieqlISEHEVEITGLTEKASSAR 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 400 KRVLEMEGKDEEIT-KTEAQCRELKKKLQEEEHHSKELRLEVEKlQKRMSE--LEKLEEAFSRSKSECTQLHLNLEKEKN 476
Cdd:pfam15921 292 SQANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELRE-AKRMYEdkIEELEKQLVLANSELTEARTERDQFSQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 477 LTKDLLNELEVVKSRVKELEcSESRLEKVELSLKDDLTKLKSFTvmlVDERKNMMEKIKQEERKVDGLNKNFKVE-QGKv 555
Cdd:pfam15921 371 ESGNLDDQLQKLLADLHKRE-KELSLEKEQNKRLWDRDTGNSIT---IDHLRRELDDRNMEVQRLEALLKAMKSEcQGQ- 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 556 mdvteklIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEE----RSCELSCSVDLLKKRLDGIEEVEREInrgrlc 631
Cdd:pfam15921 446 -------MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEeltaKKMTLESSERTVSDLTASLQEKERAI------ 512
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 632 kgsEFTCPEDNKIREltlEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFrTEQDKA-NFLSQQLEEIKH---QMAKNK 707
Cdd:pfam15921 513 ---EATNAEITKLRS---RVDLKLQELQHLKNEGDHLRNVQTECEALKLQM-AEKDKViEILRQQIENMTQlvgQHGRTA 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 708 AIEKGEAVSQEAELRHRfRME-----------EAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETK 776
Cdd:pfam15921 586 GAMQVEKAQLEKEINDR-RLElqefkilkdkkDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKT 664
|
650 660
....*....|....*....|...
gi 1270111431 777 NKNmgrEVLNLTKELELSKRYSR 799
Cdd:pfam15921 665 SRN---ELNSLSEDYEVLKRNFR 684
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
74-784 |
1.04e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 56.52 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 74 LKPSGESEKKTKKPLELSKEDLIQLLSIME-GELQAREDVIHmlKTEKTKPEVLEAHYGSAE---PEKVLRVLHRDAILA 149
Cdd:TIGR00618 148 LLPQGEFAQFLKAKSKEKKELLMNLFPLDQyTQLALMEFAKK--KSLHGKAELLTLRSQLLTlctPCMPDTYHERKQVLE 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 150 QE-KSIGEDVYEKPISE--LDRLEEKQKETYR--RMLEQLLLAEKCHRRTVYELEN---------------EKHKHTDYM 209
Cdd:TIGR00618 226 KElKHLREALQQTQQSHayLTQKREAQEEQLKkqQLLKQLRARIEELRAQEAVLEEtqerinrarkaaplaAHIKAVTQI 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 210 NK--SDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRL--------NKLRDELVKLKSFALMLVDER---------Q 270
Cdd:TIGR00618 306 EQqaQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLlqtlhsqeIHIRDAHEVATSIREISCQQHtltqhihtlQ 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 271 MHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKL 350
Cdd:TIGR00618 386 QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESA 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 351 VGLSQRIEELeETNKSLQKAEEELQELRDKIAKGECGNSSLmaevesLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEE 430
Cdd:TIGR00618 466 QSLKEREQQL-QTKEQIHLQETRKKAVVLARLLELQEEPCP------LCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 431 HHSK-------ELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECsESRLE 503
Cdd:TIGR00618 539 QLETseedvyhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC-EQHAL 617
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 504 KVELSLKDDLTKL--------KSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE 575
Cdd:TIGR00618 618 LRKLQPEQDLQDVrlhlqqcsQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 576 MEEKVYSLTKERDELMGKLRSEEERSCELSCS-VDLLKKRLDGIEEVEREINRGRlckgseftcpeDNKIRELTLEIERL 654
Cdd:TIGR00618 698 MLAQCQTLLRELETHIEEYDREFNEIENASSSlGSDLAAREDALNQSLKELMHQA-----------RTVLKARTEAHFNN 766
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 655 KKRLQQLEvvegdlmKTEDEYDQLEQKFRTEQdkanflsQQLEEIKHQMAKNKAIEKGEAVSQEAELrhrfrmeEAKSRD 734
Cdd:TIGR00618 767 NEEVTAAL-------QTGAELSHLAAEIQFFN-------RLREEDTHLLKTLEAEIGQEIPSDEDIL-------NLQCET 825
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|
gi 1270111431 735 LQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREV 784
Cdd:TIGR00618 826 LVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
327-456 |
1.32e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 56.02 E-value: 1.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 327 QEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETnksLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEME 406
Cdd:COG2433 385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQ---VERLEAEVEELEAELEEKDERIERLERELSEARSEERREI 461
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1270111431 407 GKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLqKRMSELEKLEEA 456
Cdd:COG2433 462 RKDREISRLDREIERLERELEEERERIEELKRKLERL-KELWKLEHSGEL 510
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
234-518 |
1.54e-07 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 56.21 E-value: 1.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 234 KAYQARKEKenakRLNKLRDELVKLKS---FALMLVDErqmhieQLGLQSQKVQDLTQKLReeeeKLKAITYKSKEDRQK 310
Cdd:PTZ00108 991 DLYKKRKEY----LLGKLERELARLSNkvrFIKHVING------ELVITNAKKKDLVKELK----KLGYVRFKDIIKKKS 1056
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 311 LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQriEELEETNKSLQKAEEELQELRDKIAKgecgnSS 390
Cdd:PTZ00108 1057 EKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMPIWSLTK--EKVEKLNAELEKKEKELEKLKNTTPK-----DM 1129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 391 LMAEVESLRKRVLEMEGKDEeitKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLN 470
Cdd:PTZ00108 1130 WLEDLDKFEEALEEQEEVEE---KEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEK 1206
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1270111431 471 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKS 518
Cdd:PTZ00108 1207 RKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSS 1254
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
193-749 |
1.59e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 56.21 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 193 RTVYELENEKHKHTDYMNKSDDFTNLLEQE----RERLKKLLEQ-----EKAYQARKEKENAKRLNKLRDELVKLKSFAL 263
Cdd:TIGR00606 577 DWLHSKSKEINQTRDRLAKLNKELASLEQNknhiNNELESKEEQlssyeDKLFDVCGSQDEESDLERLKEEIEKSSKQRA 656
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 264 MLVDERQMH---IEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQE 340
Cdd:TIGR00606 657 MLAGATAVYsqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQ 736
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 341 SHnrqlrlklvgLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVES---LRKRVLEMEGKDEEITKTEA 417
Cdd:TIGR00606 737 SI----------IDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvCLTDVTIMERFQMELKDVER 806
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 418 Q----------------CRELKKKLQEEEHHSKELRLEVEKLQK----RMSELEKLEEAFSRSKSECTQLHLNLEKEKNL 477
Cdd:TIGR00606 807 KiaqqaaklqgsdldrtVQQVNQEKQEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQF 886
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 478 TKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDglNKNFKveqgkvMD 557
Cdd:TIGR00606 887 EEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK--NIHGY------MK 958
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 558 VTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINrgrlckgseft 637
Cdd:TIGR00606 959 DIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRE----------- 1027
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 638 cpedNKIRELTLEIERLKKRLQQLEVVEgdlmkTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMaknkaiekgeaVSQ 717
Cdd:TIGR00606 1028 ----NELKEVEEELKQHLKEMGQMQVLQ-----MKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI-----------KHF 1087
|
570 580 590
....*....|....*....|....*....|...
gi 1270111431 718 EAELRH-RFRMEEAKSRDLQAEVQALKEKIHEL 749
Cdd:TIGR00606 1088 KKELREpQFRDAEEKYREMMIVMRTTELVNKDL 1120
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
205-792 |
3.20e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 55.06 E-value: 3.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 205 HTDYMNKSDDFTNLLEQERERL-KKLLEqekayqarKEKENAKRLNKLRDELvKLKSFALMLVDERQMHIEQLGLQSQKV 283
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEIGKNIELLnKEILE--------EAEINITNFNEIKEKL-KHYNFDDFGKEENIKYADEINKIKDDI 1120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 284 QDLTQKLREEEEKLKAITYKSK----EDRQKLLKLEvdfehkasrfsqeheemnaKLANQESHNRQLRlklvGLSQRIEE 359
Cdd:TIGR01612 1121 KNLDQKIDHHIKALEEIKKKSEnyidEIKAQINDLE-------------------DVADKAISNDDPE----EIEKKIEN 1177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 360 LEETNKSLQKAEEELQELRDKIAKGECGNSSL-------MAEVESLRKrvLEMEGKDEEITKTEAQCRELKKKLQEEEHh 432
Cdd:TIGR01612 1178 IVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLeevkginLSYGKNLGK--LFLEKIDEEKKKSEHMIKAMEAYIEDLDE- 1254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 433 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE-LEVV-----KSRV----KELECSESRL 502
Cdd:TIGR01612 1255 IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKsLKIIedfseESDIndikKELQKNLLDA 1334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 503 EKVELSLKDDLTKLKS-FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEqgkvMDVTEKLIEESKKLLKLKsEMEEKVY 581
Cdd:TIGR01612 1335 QKHNSDINLYLNEIANiYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDE----LDKSEKLIKKIKDDINLE-ECKSKIE 1409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 582 SLTKERD---------ELMGKLRSEE-------ERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGsefTCPEDNKIR 645
Cdd:TIGR01612 1410 STLDDKDidecikkikELKNHILSEEsnidtyfKNADENNENVLLLFKNIEMADNKSQHILKIKKDNA---TNDHDFNIN 1486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 646 ELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLsqqleEIKHQMAKNKAiEKGEAVSQEAELRHRF 725
Cdd:TIGR01612 1487 ELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-----AIKNKFAKTKK-DSEIIIKEIKDAHKKF 1560
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111431 726 RMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 792
Cdd:TIGR01612 1561 ILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETE 1627
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
353-792 |
4.28e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.41 E-value: 4.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 353 LSQRIEELEETNKSLQKAEEELQELRDK----------IAKGECGNSSLMAEVESLRKRVLEMEGKDEEITkteaqcREL 422
Cdd:pfam01576 7 MQAKEEELQKVKERQQKAESELKELEKKhqqlceeknaLQEQLQAETELCAEAEEMRARLAARKQELEEIL------HEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 423 KKKLQEEEHHSKELRLEVEKLQKRMSELEKL--EEAFSRSKSECTQLHLNlEKEKNLTKDLLNELEVVKSRVKELECSES 500
Cdd:pfam01576 81 ESRLEEEEERSQQLQNEKKKMQQHIQDLEEQldEEEAARQKLQLEKVTTE-AKIKKLEEDILLLEDQNSKLSKERKLLEE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 501 RLEKVELSLKDDLTKLKSFT-------VMLVDerknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEeskkllkLK 573
Cdd:pfam01576 160 RISEFTSNLAEEEEKAKSLSklknkheAMISD----LEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAE-------LQ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 574 SEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSeftcpEDNKIRELTLEIER 653
Cdd:pfam01576 229 AQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRRDLGEELEA 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 654 LK------------------KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKA-NFLSQQLEEIKH---QMAKNKAIEK 711
Cdd:pfam01576 304 LKteledtldttaaqqelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRnkaNLEKAKQALE 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 712 GEAVSQEAELR----------HRFRMEEAKSRDLQAEVQALKEKIHELmnkEDQLSQLQVDYSVLQQRFMEEETKNKNMG 781
Cdd:pfam01576 384 SENAELQAELRtlqqakqdseHKRKKLEGQLQELQARLSESERQRAEL---AEKLSKLQSELESVSSLLNEAEGKNIKLS 460
|
490
....*....|.
gi 1270111431 782 REVLNLTKELE 792
Cdd:pfam01576 461 KDVSSLESQLQ 471
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
361-738 |
4.37e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 4.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 361 EETNKSLQKAEEELQELRDkiakgecgnssLMAEVESlRKRVLEMEGKD----EEItKTEAQCRELKKKLQEEEHHSKEL 436
Cdd:COG1196 175 EEAERKLEATEENLERLED-----------ILGELER-QLEPLERQAEKaeryREL-KEELKELEAELLLLKLRELEAEL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 437 RLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKL 516
Cdd:COG1196 242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 517 KsftvmlvDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRS 596
Cdd:COG1196 322 E-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 597 EEErscelscsvdlLKKRLDGIEEVEreinrgrlckgseftcpEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYD 676
Cdd:COG1196 395 AAE-----------LAAQLEELEEAE-----------------EALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 677 QLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAE 738
Cdd:COG1196 447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
163-725 |
5.40e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 54.14 E-value: 5.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 163 ISELDRLEEKQKETYRRMLE---QLLLAEKCHRRTVYELENEKhkhTDYMNKSDDFtNLLEQERERLKKLLEQEKAYQAr 239
Cdd:PRK01156 182 ISNIDYLEEKLKSSNLELENikkQIADDEKSHSITLKEIERLS---IEYNNAMDDY-NNLKSALNELSSLEDMKNRYES- 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 240 KEKENAKRLNKLRDELVKLKSfalmlVDERQMHIE-------------------QLGLQSQKVQDLTQKLREEEEKLK-- 298
Cdd:PRK01156 257 EIKTAESDLSMELEKNNYYKE-----LEERHMKIIndpvyknrnyindyfkyknDIENKKQILSNIDAEINKYHAIIKkl 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 299 AITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLR------LKLVGLSQRIEELEETNKSLQKAEe 372
Cdd:PRK01156 332 SVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEeyskniERMSAFISEILKIQEIDPDAIKKE- 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 373 eLQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEE--EHHSKELRLEVEKLQKRMSEL 450
Cdd:PRK01156 411 -LNEINVKLQDISSKVSSLNQRIRALRENLDELS-RNMEMLNGQSVCPVCGTTLGEEksNHIINHYNEKKSRLEEKIREI 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 451 EKLEEAFSRSKSECTQLHLNLEKEK-NLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERK- 528
Cdd:PRK01156 489 EIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRt 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 529 ---NMMEKIKQEErkVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS-------EMEEKVYSLTKERDELMGKLRSEE 598
Cdd:PRK01156 569 swlNALAVISLID--IETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSyidksirEIENEANNLNNKYNEIQENKILIE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 599 ErsceLSCSVDLLKKRLDGIEEVEREINrgrlckgseftcpednkirELTLEIERLKKRLQQlevVEGDLMKTEDEYDQL 678
Cdd:PRK01156 647 K----LRGKIDNYKKQIAEIDSIIPDLK-------------------EITSRINDIEDNLKK---SRKALDDAKANRARL 700
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1270111431 679 EQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKgeAVSQEAELRHRF 725
Cdd:PRK01156 701 ESTIEILRTRINELSDRINDINETLESMKKIKK--AIGDLKRLREAF 745
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
88-792 |
5.95e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.03 E-value: 5.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 88 LELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEV----LEAHYGSAE--------------------PEKVLRVLH 143
Cdd:pfam01576 66 LAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQhiqdLEEQLDEEEaarqklqlekvtteakikklEEDILLLED 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 144 RDAILAQEKSIGEDVYEKPISELDRLEEKQKE------TYRRMLEQLLLAEKCHRRTVYELENEKHkhtdymnKSDDFTN 217
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEKAKSlsklknKHEAMISDLEERLKKEEKGRQELEKAKR-------KLEGEST 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 218 LLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKlKSFALMLVDERQMHIEQLG-------LQSQKVQDLTQKL 290
Cdd:pfam01576 219 DLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQ-KNNALKKIRELEAQISELQedleserAARNKAEKQRRDL 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 291 REEEEKLKA-------ITYKSKEDR----QKLLKLEVDFEHKASRFSQEHEEMNAKlanqesHNRQlrlkLVGLSQRIEE 359
Cdd:pfam01576 298 GEELEALKTeledtldTTAAQQELRskreQEVTELKKALEEETRSHEAQLQEMRQK------HTQA----LEELTEQLEQ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 360 LEETNKSLQKAEEELqelrdkiakgECGNSSLMAEVESLRKRVLEMEGKDEeitKTEAQCRELKKKLQEEEHHSKELrle 439
Cdd:pfam01576 368 AKRNKANLEKAKQAL----------ESENAELQAELRTLQQAKQDSEHKRK---KLEGQLQELQARLSESERQRAEL--- 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 440 VEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDllnelevvksrVKELECSESRlEKVELSlkddlTKLKSf 519
Cdd:pfam01576 432 AEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQD-----------TQELLQEETR-QKLNLS-----TRLRQ- 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 520 tvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLlklkSEMEEKVYSLTKERDELMGKLRSEEE 599
Cdd:pfam01576 494 ---LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL----EALEEGKKRLQRELEALTQQLEEKAA 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 600 rscelscSVDLLKKrldgieevereiNRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDL-MKTEDEYDQL 678
Cdd:pfam01576 567 -------AYDKLEK------------TKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAIsARYAEERDRA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 679 EQKFRTEQDKANFLSQQLEEIKHQMAK----NKAI--EKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNK 752
Cdd:pfam01576 628 EAEAREKETRALSLARALEEALEAKEElertNKQLraEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDE 707
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 753 ----EDQLSQLQVDYSVLQQRFMEE--------ETKNKNMGREVLNLTKELE 792
Cdd:pfam01576 708 lqatEDAKLRLEVNMQALKAQFERDlqardeqgEEKRRQLVKQVRELEAELE 759
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
482-811 |
6.52e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.92 E-value: 6.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 482 LNELEVVKSRVKELECSES----RLEKVE------LSLKDDLTKLKSFTVMLVDERKNMMEK-IKQEERKVDGLNKnfkv 550
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDekrqQLERLRrerekaERYQALLKEKREYEGYELLKEKEALERqKEAIERQLASLEE---- 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 551 EQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERdelMGKLRSEEErscELSCSVDLLKkrlDGIEEVEREINR--G 628
Cdd:TIGR02169 252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE---QLRVKEKIG---ELEAEIASLE---RSIAEKERELEDaeE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 629 RLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEV----VEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQM- 703
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEeyaeLKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIn 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 704 -----AKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHElmnKEDQLSQLQVDYSVLQQRFMEEETKNK 778
Cdd:TIGR02169 403 elkreLDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK---QEWKLEQLAADLSKYEQELYDLKEEYD 479
|
330 340 350
....*....|....*....|....*....|...
gi 1270111431 779 NMGREVLNLTKELELSKRYSRALRPSGNGRRMV 811
Cdd:TIGR02169 480 RVEKELSKLQRELAEAEAQARASEERVRGGRAV 512
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
274-796 |
8.86e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 53.64 E-value: 8.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 274 EQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSqEHEEMNAKLANQEshnRQLRLKLVGL 353
Cdd:pfam01576 5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCA-EAEEMRARLAARK---QELEEILHEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 354 SQRIEELEETNKSLQ----KAEEELQELRDKIAKGECGNSSLM-------AEVESLRKRVLEMEGKDEEITKT----EAQ 418
Cdd:pfam01576 81 ESRLEEEEERSQQLQnekkKMQQHIQDLEEQLDEEEAARQKLQlekvtteAKIKKLEEDILLLEDQNSKLSKErkllEER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 419 CRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECS 498
Cdd:pfam01576 161 ISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL---QAQIAELRAQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 499 esrLEKVELSLKDDLTKLKSFTVmlvdERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 578
Cdd:pfam01576 238 ---LAKKEEELQAALARLEEETA----QKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELED 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 579 KVYSLTKERDelmgkLRSEEERScelscsVDLLKKRLDgieeverEINRGRLCKGSEFTCPEDNKIRELTLEIERLKKRL 658
Cdd:pfam01576 311 TLDTTAAQQE-----LRSKREQE------VTELKKALE-------EETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNK 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 659 QQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI--KHQMAKNKAIEKGEAVSQ-EAELR---HRFRME 728
Cdd:pfam01576 373 ANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqaRLSESERQRAELAEKLSKlQSELEsvsSLLNEA 452
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1270111431 729 EAKSRDLQAEVQALKEKIH---ELMNKEDQ--------LSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELELSKR 796
Cdd:pfam01576 453 EGKNIKLSKDVSSLESQLQdtqELLQEETRqklnlstrLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
37-770 |
1.42e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.92 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 37 SIISSDGGKGPSEDAKKNKANRKGED-DVMASGTVKRHLKPSGESEKKTKKPLELSkedliqlLSIMEGELQAREDVIHM 115
Cdd:pfam12128 204 AILEDDGVVPPKSRLNRQQVEHWIRDiQAIAGIMKIRPEFTKLQQEFNTLESAELR-------LSHLHFGYKSDETLIAS 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 116 LKTEKTKpevleahyGSAEPEKVLRVLHRD-----AILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLaekc 190
Cdd:pfam12128 277 RQEERQE--------TSAELNQLLRTLDDQwkekrDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAA---- 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 191 hrrtvyELENEkhkhtdymnksDDFTNLLEQERERLKKLLEQ----EKAYQARKEK---ENAKRLNKLRDELVKLKSFAL 263
Cdd:pfam12128 345 ------DQEQL-----------PSWQSELENLEERLKALTGKhqdvTAKYNRRRSKikeQNNRDIAGIKDKLAKIREARD 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 264 MLVDERQMHIEQL----------GLQSQKVQDLTQKLREEEEKLK--AITYKSKEDRQKllklevdfEHKASRFSQEHEE 331
Cdd:pfam12128 408 RQLAVAEDDLQALeselreqleaGKLEFNEEEYRLKSRLGELKLRlnQATATPELLLQL--------ENFDERIERAREE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 332 MNAKLANQES--------------HNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVES 397
Cdd:pfam12128 480 QEAANAEVERlqselrqarkrrdqASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPEL 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 398 LRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEH-----HSKELRLEVEKL----------QKRMSE--------LEKLE 454
Cdd:pfam12128 560 LHRTDLDPE-VWDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAeealqsarekQAAAEEqlvqangeLEKAS 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 455 EAFSRSKSECTQLHLNLEKEKNLTKDLlnELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDE-RKNMMEK 533
Cdd:pfam12128 639 REETFARTALKNARLDLRRLFDEKQSE--KDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQkREARTEK 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 534 ikQEERKVdglnknfkVEQGKvmDVTEKLIEESKklLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK 613
Cdd:pfam12128 717 --QAYWQV--------VEGAL--DAQLALLKAAI--AARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLER 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 614 RLDGIEEVEREINRGRLCKGSEFTCPEDN----------KIRELTLEIERL----KKRLQQLEVVEGDLMKTEDEYDQLE 679
Cdd:pfam12128 783 KIERIAVRRQEVLRYFDWYQETWLQRRPRlatqlsnierAISELQQQLARLiadtKLRRAKLEMERKASEKQQVRLSENL 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 680 QKFRTEQDKANFLS--QQLEEIKHQMAKN-------KAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEV-QALKEKIHEL 749
Cdd:pfam12128 863 RGLRCEMSKLATLKedANSEQAQGSIGERlaqledlKLKRDYLSESVKKYVEHFKNVIADHSGSGLAETwESLREEDHYQ 942
|
810 820
....*....|....*....|.
gi 1270111431 750 MNKEDQLSQLQVDYSVLQQRF 770
Cdd:pfam12128 943 NDKGIRLLDYRKLVPYLEQWF 963
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
289-752 |
1.66e-06 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 52.15 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 289 KLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEM-NAKLANQESHnrqlrlklvglsqrIEELEETNKS- 366
Cdd:PRK04778 33 ELEERKQELENLPVNDELEKVKKLNLTGQSEEKFEEWRQKWDEIvTNSLPDIEEQ--------------LFEAEELNDKf 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 367 -LQKAEEELQELRDKIAKGEcgnsslmAEVESLRKRVLEMEGKDE----EITKTEAQCRELKKKLQEEEHHSKELrleVE 441
Cdd:PRK04778 99 rFRKAKHEINEIESLLDLIE-------EDIEQILEELQELLESEEknreEVEQLKDLYRELRKSLLANRFSFGPA---LD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 442 KLQKRMSELEKLEEAFSRSKSE--CTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcsesrlekveLSLKDDLTKLKS- 518
Cdd:PRK04778 169 ELEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAALEQIMEEIPELLKELQ----------TELPDQLQELKAg 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 519 FTVMLVD----ERKNMMEKIKQEERKVDGLNKNfkVEQGKVMDVTEKLIEESKKLLKLKSEMEEKV---YSLTKERDELM 591
Cdd:PRK04778 239 YRELVEEgyhlDHLDIEKEIQDLKEQIDENLAL--LEELDLDEAEEKNEEIQERIDQLYDILEREVkarKYVEKNSDTLP 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 592 GKLRSEEERSCELSCSVDLLKKR-------LDGIEEVEREINRgrlckgseftcpednkIRELTLEI------------- 651
Cdd:PRK04778 317 DFLEHAKEQNKELKEEIDRVKQSytlneseLESVRQLEKQLES----------------LEKQYDEIteriaeqeiayse 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 652 --ERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK--------------NKAIEKGEAV 715
Cdd:PRK04778 381 lqEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNKLHEIKRYLEKsnlpglpedylemfFEVSDEIEAL 460
|
490 500 510
....*....|....*....|....*....|....*....
gi 1270111431 716 SQEAElRHRFRMEE--AKSRDLQAEVQALKEKIHELMNK 752
Cdd:PRK04778 461 AEELE-EKPINMEAvnRLLEEATEDVETLEEETEELVEN 498
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
349-752 |
2.06e-06 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 51.78 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 349 KLVGLSQRIEELEETNKS--LQKAEEELQELRDKIAKGEcgnsslmAEVESLRKRVLEMEGKDE----EITKTEAQCREL 422
Cdd:pfam06160 61 SLPDIEELLFEAEELNDKyrFKKAKKALDEIEELLDDIE-------EDIKQILEELDELLESEEknreEVEELKDKYREL 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 423 KKKLQEEEHHSKELrleVEKLQKRMSELEKLEEAFSRSKSECtqlhlNLEKEKNLTKDLLNELEVVKSRVKELEcseSRL 502
Cdd:pfam06160 134 RKTLLANRFSYGPA---IDELEKQLAEIEEEFSQFEELTESG-----DYLEAREVLEKLEEETDALEELMEDIP---PLY 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 503 EKVELSLKDDLTKLKS-FTVMLVD----ERKNMMEKIKQEERKVDGLNKNFK------VEQG---------KVMDVTEKL 562
Cdd:pfam06160 203 EELKTELPDQLEELKEgYREMEEEgyalEHLNVDKEIQQLEEQLEENLALLEnleldeAEEAleeieeridQLYDLLEKE 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 563 IEESKKLLKLKSEMEEKVYSLTKERDELMGKLR----------SEEERSCELSCSVDLLKKRLDGIEEVEreinrgrlck 632
Cdd:pfam06160 283 VDAKKYVEKNLPEIEDYLEHAEEQNKELKEELErvqqsytlneNELERVRGLEKQLEELEKRYDEIVERL---------- 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 633 gseftcpEDNKIRELTLEiERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK------- 705
Cdd:pfam06160 353 -------EEKEVAYSELQ-EELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLELREIKRLVEKsnlpglp 424
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111431 706 -------NKAIEKGEAVSQEAElRHRFRMEE--AKSRDLQAEVQALKEKIHELMNK 752
Cdd:pfam06160 425 esyldyfFDVSDEIEDLADELN-EVPLNMDEvnRLLDEAQDDVDTLYEKTEELIDN 479
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
306-460 |
2.61e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 306 EDRQKLLKLEvDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEetnKSLQKAEEELQELRDKIAK-- 383
Cdd:COG1579 4 EDLRALLDLQ-ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLE---KEIKRLELEIEEVEARIKKye 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 384 ---GECGNS----SLMAEVESLRKR--VLE---------MEGKDEEITKTEAQCRELKKKLQEEEhhsKELRLEVEKLQK 445
Cdd:COG1579 80 eqlGNVRNNkeyeALQKEIESLKRRisDLEdeilelmerIEELEEELAELEAELAELEAELEEKK---AELDEELAELEA 156
|
170
....*....|....*
gi 1270111431 446 RMSELEKLEEAFSRS 460
Cdd:COG1579 157 ELEELEAEREELAAK 171
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
371-803 |
2.74e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 2.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 371 EEELQELRDKIAKGECGNSSL-MAEVESLRKRVlemegkdEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSE 449
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELnLKELKELEEEL-------KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 450 LEKLEEAFSRSKsECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKddlTKLKSFTVMLVDERKN 529
Cdd:COG4717 121 LEKLLQLLPLYQ-ELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELE---ELLEQLSLATEEELQD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 530 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLksEMEEKVY-------------SLTKERDELMG---- 592
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA--ALEERLKearlllliaaallALLGLGGSLLSlilt 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 593 ------------------------KLRSEEERSCELSCSVDLLKKRLDGIEEvEREINRGRLCKGSEFTCPEDNKIRELT 648
Cdd:COG4717 275 iagvlflvlgllallflllarekaSLGKEAEELQALPALEELEEEELEELLA-ALGLPPDLSPEELLELLDRIEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 649 LEIERLKKRLQQL-------EVVEGDLMKTEDEYDQLEQKFRTEQDkanfLSQQLEEIKHQM-AKNKAIEKGEAVSQEAE 720
Cdd:COG4717 354 REAEELEEELQLEeleqeiaALLAEAGVEDEEELRAALEQAEEYQE----LKEELEELEEQLeELLGELEELLEALDEEE 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 721 LRHRFRMEEAKSRDLQAEVQALKEKIHELmnkEDQLSQLQVD--YSVLQQRFMEEETKNKNMGRE--VLNLTKEL--ELS 794
Cdd:COG4717 430 LEEELEELEEELEELEEELEELREELAEL---EAELEQLEEDgeLAELLQELEELKAELRELAEEwaALKLALELleEAR 506
|
....*....
gi 1270111431 795 KRYSRALRP 803
Cdd:COG4717 507 EEYREERLP 515
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
287-504 |
3.01e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 3.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 287 TQKLREEEEKLKAITYKSKEDRQKLLKLEVdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEetnKS 366
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE---KE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 367 LQKAEEELQELRDKIAK--------GECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL 438
Cdd:COG4942 92 IAELRAELEAQKEELAEllralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111431 439 EVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECSESRLEK 504
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL---QQEAEELEALIARLEA 234
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
279-518 |
3.43e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 51.17 E-value: 3.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 279 QSQKVQDLTQKLREEEEKLKaiTYKSKEDRQkllklevdfEHKASRFSQEHEEMNAKLANQESHNRQLrlklvgLSQRIE 358
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIK--TYNKNIEEQ---------RKKNGENIARKQNKYDELVEEAKTIKAE------IEELTD 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 359 ELEETNKSLQKAEEELQELRDKIAKgecgnssLMAEVESLRKrVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL 438
Cdd:PHA02562 242 ELLNLVMDIEDPSAALNKLNTAAAK-------IKSKIEQFQK-VIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 439 EVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcSESRLEKVELS-LKDDLTKLK 517
Cdd:PHA02562 314 SLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ-AEFVDNAEELAkLQDELDKIV 392
|
.
gi 1270111431 518 S 518
Cdd:PHA02562 393 K 393
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
197-787 |
4.34e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 51.20 E-value: 4.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 197 ELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQL 276
Cdd:TIGR00606 232 QLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRK--KQMEKDNSELELKMEKVFQGTDEQLNDLYHN 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 277 glQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKlaNQESHNRQLRLKLVGLsQR 356
Cdd:TIGR00606 310 --HQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRAR--DSLIQSLATRLELDGF-ER 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 357 IEELEETNKSLQKAEEELQELRDKIAKGECGN--SSLMAEVESLRKRVLEMEG-------KDEEITKTEAQCRELKKKLQ 427
Cdd:TIGR00606 385 GPFSERQIKNFHTLVIERQEDEAKTAAQLCADlqSKERLKQEQADEIRDEKKGlgrtielKKEILEKKQEELKFVIKELQ 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 428 EEEHHSKELRLEVEKLQKRMSELEKLEEafsRSKSECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVEL 507
Cdd:TIGR00606 465 QLEGSSDRILELDQELRKAERELSKAEK---NSLTET--LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 508 SLKDDLT------KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 581
Cdd:TIGR00606 540 LTKDKMDkdeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEE 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 582 SLTKERDELMGKLRSEEERScelscSVDLLKKRLdgieeverEINRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQL 661
Cdd:TIGR00606 620 QLSSYEDKLFDVCGSQDEES-----DLERLKEEI--------EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 662 EVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQM---AKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAE 738
Cdd:TIGR00606 687 FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlglAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND 766
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1270111431 739 VQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNL 787
Cdd:TIGR00606 767 IEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL 815
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
217-432 |
7.47e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 50.01 E-value: 7.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 217 NLLEQERERLKKLLEQEKAyqarKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEK 296
Cdd:PHA02562 191 DHIQQQIKTYNKNIEEQRK----KNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 297 LKAitykskeDRQKLLKLEVDFE--HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEEL 374
Cdd:PHA02562 267 IKS-------KIEQFQKVIKMYEkgGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKL 339
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111431 375 QELRDKIAKGECGNSSLMAEVESLRKRVLEMEG----KDEEITKTEAQCRELKKKLQE---EEHH 432
Cdd:PHA02562 340 LELKNKISTNKQSLITLVDKAKKVKAAIEELQAefvdNAEELAKLQDELDKIVKTKSElvkEKYH 404
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
313-690 |
8.14e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 50.36 E-value: 8.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 313 KLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKgecgnsslm 392
Cdd:pfam02463 155 RLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY--------- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 393 aeVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLE 472
Cdd:pfam02463 226 --LLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 473 KEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKvdglnknfkveQ 552
Cdd:pfam02463 304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL-----------E 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 553 GKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSvdllKKRLDGIEEVEREINRGRLCK 632
Cdd:pfam02463 373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE----ELEILEEEEESIELKQGKLTE 448
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111431 633 GSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKAN 690
Cdd:pfam02463 449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
353-780 |
1.06e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 49.90 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 353 LSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHH 432
Cdd:PRK01156 192 LKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEK 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 433 SKELRLEVEKLQKRMS------------------ELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDlLNELEVVKSRVKE 494
Cdd:PRK01156 272 NNYYKELEERHMKIINdpvyknrnyindyfkyknDIENKKQILSNIDAEINKYHAIIKKLSVLQKD-YNDYIKKKSRYDD 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 495 LEcsesrlekvelSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 574
Cdd:PRK01156 351 LN-----------NQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQ 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 575 EMEEKVYSLTKERDELMGKLRSEEERSCELS-------CSVDLlkkrldGIEEVEREINR--GRLCKGSEFTCPEDNKIR 645
Cdd:PRK01156 420 DISSKVSSLNQRIRALRENLDELSRNMEMLNgqsvcpvCGTTL------GEEKSNHIINHynEKKSRLEEKIREIEIEVK 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 646 ELTLEIERLKKRLQQLEvvEGDLMKTEDEYDQLEQKfrteqdkanflSQQLEEIKHQMAKNKaiekgeavsqEAELRHrf 725
Cdd:PRK01156 494 DIDEKIVDLKKRKEYLE--SEEINKSINEYNKIESA-----------RADLEDIKIKINELK----------DKHDKY-- 548
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1270111431 726 rmEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysVLQQRFMEEETKNKNM 780
Cdd:PRK01156 549 --EEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIE--TNRSRSNEIKKQLNDL 599
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
219-799 |
1.14e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.79 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 219 LEQERERLKKLLEQEKAYQARKEKEnaKRlnKLRDELVKLKSfalMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 298
Cdd:pfam01576 269 LEAQISELQEDLESERAARNKAEKQ--RR--DLGEELEALKT---ELEDTLDTTAAQQELRSKREQEVTELKKALEEETR 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 299 AITYKSKEDRQK----LLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLKLVGLSQRIEELEETNKslqKAEEEL 374
Cdd:pfam01576 342 SHEAQLQEMRQKhtqaLEELTEQLE-QAKRNKANLEKAKQAL---ESENAELQAELRTLQQAKQDSEHKRK---KLEGQL 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 375 QELRDKIAKGECGN-------SSLMAEVESLRKRVLEMEGKD----EEITKTEAQCRELKKKLQEEEHH-----SKELRL 438
Cdd:pfam01576 415 QELQARLSESERQRaelaeklSKLQSELESVSSLLNEAEGKNiklsKDVSSLESQLQDTQELLQEETRQklnlsTRLRQL 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 439 EVEK--LQKRMSELEKLEEAFSR-----------SKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKV 505
Cdd:pfam01576 495 EDERnsLQEQLEEEEEAKRNVERqlstlqaqlsdMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 506 ELSLKDDLTKLksftVMLVDERKNMMEKIKQEERKVDGLNKNFKVeqgkvmdVTEKLIEESKKLLKLKSEMEEKVYSLTK 585
Cdd:pfam01576 575 KNRLQQELDDL----LVDLDHQRQLVSNLEKKQKKFDQMLAEEKA-------ISARYAEERDRAEAEAREKETRALSLAR 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 586 ERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRlckgseftcpednkiRELTLEIERLKkrlQQLEVVE 665
Cdd:pfam01576 644 ALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSK---------------RALEQQVEEMK---TQLEELE 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 666 GDLMKTEDEYDQLE---QKFRTEQDK-ANFLSQQLEEIKHQMAKN---KAIEKGEAVSQEAELRHRFRMEEAKSRDLQAE 738
Cdd:pfam01576 706 DELQATEDAKLRLEvnmQALKAQFERdLQARDEQGEEKRRQLVKQvreLEAELEDERKQRAQAVAAKKKLELDLKELEAQ 785
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 739 VQAL----KEKIHELMNKEDQLSQLQVDYSVLQQ-------RFMEEETKNKNMGREVLNLTKELELSKRYSR 799
Cdd:pfam01576 786 IDAAnkgrEEAVKQLKKLQAQMKDLQRELEEARAsrdeilaQSKESEKKLKNLEAELLQLQEDLAASERARR 857
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
327-743 |
1.15e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 49.30 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 327 QEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEME 406
Cdd:pfam19220 3 QRNELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 407 GkdeEITKTEAQCRELKKKLQEEEHHSKELRLEvekLQKRMSELEKLEeafsrsksecTQLHLNLEKEKNLT---KDLLN 483
Cdd:pfam19220 83 G---ELEELVARLAKLEAALREAEAAKEELRIE---LRDKTAQAEALE----------RQLAAETEQNRALEeenKALRE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 484 ELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSftvmLVDErknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLI 563
Cdd:pfam19220 147 EAQAAEKALQRAEGELATARERLALLEQENRRLQA----LSEE---QAAELAELTRRLAELETQLDATRARLRALEGQLA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 564 EESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRgrlckgseftcpednK 643
Cdd:pfam19220 220 AEQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAER---------------R 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 644 IRELTLEIERLKKRlqqLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEeikhqmAKNKAIEKGE---AVSQE-- 718
Cdd:pfam19220 285 LKEASIERDTLERR---LAGLEADLERRTQQFQEMQRARAELEERAEMLTKALA------AKDAALERAEeriASLSDri 355
|
410 420
....*....|....*....|....*....
gi 1270111431 719 AELRHRFRME----EAKSRDLQAEVQALK 743
Cdd:pfam19220 356 AELTKRFEVEraalEQANRRLKEELQRER 384
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
281-603 |
1.27e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 48.75 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 281 QKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLevdfEHKASRFSQEHEEMNAKLanqeshnRQLRLKlvgLSQRIEEL 360
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKRDEL----NEELKELAEKRDELNAQV-------KELREE---AQELREKR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 361 EETNKSLQKAEEELQELRDKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEV 440
Cdd:COG1340 67 DELNEKVKELKEERDELNEKL-------NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELV 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 441 EKLQKRMSELEKLEEAfsrsksectqlhlnlEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFT 520
Cdd:COG1340 140 EKIKELEKELEKAKKA---------------LEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEA 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 521 VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvySLTKERDELMGKLRSEEER 600
Cdd:COG1340 205 DELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKE--ELEEKAEEIFEKLKKGEKL 282
|
...
gi 1270111431 601 SCE 603
Cdd:COG1340 283 TTE 285
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
167-542 |
1.36e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.12 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 167 DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE----KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQArkek 242
Cdd:pfam07888 54 NRQREKEKERYKRDREQWERQRRELESRVAELKEElrqsREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEA---- 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 243 enakRLNKLRDELVKLKSFALmlvdERQMHIEQLglqSQKVQDLTQKLREEEEklkaitykskEDRQKLLKLEVDfEHKA 322
Cdd:pfam07888 130 ----RIRELEEDIKTLTQRVL----ERETELERM---KERAKKAGAQRKEEEA----------ERKQLQAKLQQT-EEEL 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 323 SRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESL---R 399
Cdd:pfam07888 188 RSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMaaqR 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 400 KRVL-EMEGKDEEITKTEAQCRELKKKLQEEEHHSKELR--------LEVEKLQKRMSELEKLEEAFSRSKSECTQLHLN 470
Cdd:pfam07888 268 DRTQaELHQARLQAAQLTLQLADASLALREGRARWAQERetlqqsaeADKDRIEKLSAELQRLEERLQEERMEREKLEVE 347
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 471 LEKEKNLtkdllnelevvkSRVkelECSESRLEKVElsLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 542
Cdd:pfam07888 348 LGREKDC------------NRV---QLSESRRELQE--LKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
164-366 |
1.41e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 164 SELDRLEEKQKETyRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKE 243
Cdd:COG4942 27 AELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 244 NAKRLNKL---------------RDELVKLKSFALM--LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKE 306
Cdd:COG4942 106 LAELLRALyrlgrqpplalllspEDFLDAVRRLQYLkyLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 307 DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKS 366
Cdd:COG4942 186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
165-436 |
1.57e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 165 ELDRL-EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKsddftnllEQERERLKKLLEQEKAyqaRKEKE 243
Cdd:pfam17380 349 ELERIrQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQ--------ELEAARKVKILEEERQ---RKIQQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 244 NAKRLNKLRDELVKLKSFAL-MLVDERQMHIEQLGLQSQKVQDLTQKLREEEEklkaitykskEDRQKLLKLEvdfehKA 322
Cdd:pfam17380 418 QKVEMEQIRAEQEEARQREVrRLEEERAREMERVRLEEQERQQQVERLRQQEE----------ERKRKKLELE-----KE 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 323 SRFSQEHEEMNAKLANQESHNRQlrlklvglsQRIEELEETNKSLQKAEEELQ-----ELRDKIAKGECGNSSLMAEves 397
Cdd:pfam17380 483 KRDRKRAEEQRRKILEKELEERK---------QAMIEEERKRKLLEKEMEERQkaiyeEERRREAEEERRKQQEMEE--- 550
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1270111431 398 lRKRVLE-MEGKDEEITKTEA--QCRELKKKLQEEEHHSKEL 436
Cdd:pfam17380 551 -RRRIQEqMRKATEERSRLEAmeREREMMRQIVESEKARAEY 591
|
|
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
410-528 |
1.60e-05 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 46.83 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 410 EEITKTEAQCRELKKKLQEeehhskeLRLEVEKLQKRMS---ELEKLEEAFSRSKSECTQLHLNLEKEKnltkdLLNELE 486
Cdd:pfam09727 80 AELEKLVEKQRETQRRMLE-------QLAAAEKRHRRVIrelEEEKRKHARDTAQGDDFTYLLEKERER-----LKQELE 147
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1270111431 487 VVKSRVKELEcseSRLEKVELSLKDDLTKLKSFTVMLVDERK 528
Cdd:pfam09727 148 QEKAQQKRLE---KELKKLLEKLEEELSKQKQIALLLVKERK 186
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
389-620 |
1.62e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 389 SSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRSKSEC 464
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaaLEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 465 TQLHLNLEKEKNLTKDLLNELEVVkSRVKELecsesrleKVELSLKDDLTKLKSFTVM--LVDERKNMMEKIKQEERKVD 542
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRL-GRQPPL--------ALLLSPEDFLDAVRRLQYLkyLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111431 543 GLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEE 620
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
299-457 |
2.75e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 48.32 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 299 AITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQ----ESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEEL 374
Cdd:COG2433 381 ALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQverlEAEVEELEAELEEKDERIERLERELSEARSEERRE 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 375 QELRDKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLqeeehHSKELR--LEVEKLQKrmSELEK 452
Cdd:COG2433 461 IRKDREI-------SRLDREIERLERELEEERERIEELKRKLERLKELWKLE-----HSGELVpvKVVEKFTK--EAIRR 526
|
....*
gi 1270111431 453 LEEAF 457
Cdd:COG2433 527 LEEEY 531
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
444-779 |
2.75e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.81 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 444 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL----EKVELSLKDDLTKLKSf 519
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLyldyLKLNEERIDLLQELLR- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 520 tvMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL------MGK 593
Cdd:pfam02463 248 --DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesekeKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 594 LRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTED 673
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 674 EYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDL-QAEVQALKEKIHELMNK 752
Cdd:pfam02463 406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELkKSEDLLKETQLVKLQEQ 485
|
330 340
....*....|....*....|....*..
gi 1270111431 753 EDQLSQLQVDYSVLQQRFMEEETKNKN 779
Cdd:pfam02463 486 LELLLSRQKLEERSQKESKARSGLKVL 512
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
523-762 |
3.12e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.21 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 523 LVDERKNMMEKIKQEERKVDGLN---KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEE 599
Cdd:COG1340 13 LEEKIEELREEIEELKEKRDELNeelKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELRE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 600 RSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEdnKIRELTLEIERLKKRLQQLEV---VEGDLMKTEDEYD 676
Cdd:COG1340 93 ELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPE--EEKELVEKIKELEKELEKAKKaleKNEKLKELRAELK 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 677 QLEQKFRTEQDKANFLSQQLEEIKHQMAKNKaiEKGEAVSQEA-ELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQ 755
Cdd:COG1340 171 ELRKEAEEIHKKIKELAEEAQELHEEMIELY--KEADELRKEAdELHKEIVEAQEKADELHEEIIELQKELRELRKELKK 248
|
....*..
gi 1270111431 756 LSQLQVD 762
Cdd:COG1340 249 LRKKQRA 255
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
367-542 |
3.88e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.46 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 367 LQKAEEELQELRDKIAKgecgnssLMAEVESLRKrvlEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR 446
Cdd:COG1579 12 LQELDSELDRLEHRLKE-------LPAELAELED---ELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 447 MSELEKLEEAFSRSKsECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLEKVELSLKDDLTKLKSFTVMLVDE 526
Cdd:COG1579 82 LGNVRNNKEYEALQK-EIESLKRRISDLEDEILELMERIEELEEELAEL---EAELAELEAELEEKKAELDEELAELEAE 157
|
170
....*....|....*.
gi 1270111431 527 RKNMMEKIKQEERKVD 542
Cdd:COG1579 158 LEELEAEREELAAKIP 173
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
532-757 |
4.32e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 47.70 E-value: 4.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 532 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL---MGKLRSEEERscelscsv 608
Cdd:PHA02562 195 QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPsaaLNKLNTAAAK-------- 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 609 dlLKKRLDGIEEVEREINRGRLCKgsefTC-----PEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 683
Cdd:PHA02562 267 --IKSKIEQFQKVIKMYEKGGVCP----TCtqqisEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL 340
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111431 684 TEQDKanfLSQQLEEIKHQMAKNKAIEKgeaVSQEAELRHRFRMEEAKSrdLQAEVQALKEKIHELMNKEDQLS 757
Cdd:PHA02562 341 ELKNK---ISTNKQSLITLVDKAKKVKA---AIEELQAEFVDNAEELAK--LQDELDKIVKTKSELVKEKYHRG 406
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
277-568 |
4.33e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 47.97 E-value: 4.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 277 GLQSQKVQDLTQKLREEEEK---LKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--KLANQE-SHNRQLRLKL 350
Cdd:PLN02939 124 QLSDFQLEDLVGMIQNAEKNillLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDAriKLAAQEkIHVEILEEQL 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 351 VGLSQRIEELEETNKSLQKA-EEELQELRDKiakgecgNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEE 429
Cdd:PLN02939 204 EKLRNELLIRGATEGLCVHSlSKELDVLKEE-------NMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLREL 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 430 EHHSKELRLEVEKLQKR-----MSELEKLEEAFSRSKSECTQLHLNLEKEKnltkDLLNELEVVKSRVKELECSESRLEK 504
Cdd:PLN02939 277 ESKFIVAQEDVSKLSPLqydcwWEKVENLQDLLDRATNQVEKAALVLDQNQ----DLRDKVDKLEASLKEANVSKFSSYK 352
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111431 505 VELSLKddltKLKsftvmLVDERknmMEKIKQEERKVDGLNKNFKVEqgkVMDVTEKLIEESKK 568
Cdd:PLN02939 353 VELLQQ----KLK-----LLEER---LQASDHEIHSYIQLYQESIKE---FQDTLSKLKEESKK 401
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
227-452 |
4.65e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 4.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 227 KKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDErqmHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKskE 306
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPE---ELLELLDRIEELQELLREAEELEEELQLEELE--Q 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 307 DRQKLLKL-----EVDFEHKASRFSQEHE------EMNAKLANQESHNRQLrLKLVGLSQRIEELEETNKSLQKAEEELQ 375
Cdd:COG4717 371 EIAALLAEagvedEEELRAALEQAEEYQElkeeleELEEQLEELLGELEEL-LEALDEEELEEELEELEEELEELEEELE 449
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111431 376 ELRDKIAKgecgnsslmaevesLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK 452
Cdd:COG4717 450 ELREELAE--------------LEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
213-493 |
5.34e-05 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 47.54 E-value: 5.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 213 DDFTNLLEQE---RERLKKLLEQ----EKAYQARKEK-ENA-----KRLNKLRDELVKLKSF--------ALMLVDERQM 271
Cdd:pfam06160 107 EELDELLESEeknREEVEELKDKyrelRKTLLANRFSyGPAideleKQLAEIEEEFSQFEELtesgdyleAREVLEKLEE 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 272 HIEQLGLQSQKV----QDLTQKLREEEEKLKAiTYkskedrQKLLKLEVDFEHKAsrFSQEHEEMNAKLANQESHNRQLR 347
Cdd:pfam06160 187 ETDALEELMEDIpplyEELKTELPDQLEELKE-GY------REMEEEGYALEHLN--VDKEIQQLEEQLEENLALLENLE 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 348 LK-----LVGLSQRIEEL----EETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKR-------VLEMEGKDEE 411
Cdd:pfam06160 258 LDeaeeaLEEIEERIDQLydllEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSytlneneLERVRGLEKQ 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 412 ITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSectqlhlNLEKEKNLTKDLLNELEVVKSR 491
Cdd:pfam06160 338 LEELEKRYDEIVERLEEKEVAYSELQEELEEILEQLEEIEEEQEEFKESLQ-------SLRKDELEAREKLDEFKLELRE 410
|
..
gi 1270111431 492 VK 493
Cdd:pfam06160 411 IK 412
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
560-802 |
6.76e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 46.44 E-value: 6.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 560 EKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINrgrlckgseftcp 639
Cdd:COG1340 18 EELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELN------------- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 640 edNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQ----------DKANFLSQQLEEIKHQMAKNKAI 709
Cdd:COG1340 85 --EKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKALEKNEKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 710 EkgEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLS----QLQVDYSVLQQRFMEEETKNKNMGREVL 785
Cdd:COG1340 163 K--ELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRkeadELHKEIVEAQEKADELHEEIIELQKELR 240
|
250
....*....|....*..
gi 1270111431 786 NLTKELELSKRYSRALR 802
Cdd:COG1340 241 ELRKELKKLRKKQRALK 257
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
650-772 |
7.17e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 650 EIERLKKRLQQLEVvegdlmktedEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKnkaiekgEAVSQEAELRHRFRMEE 729
Cdd:COG3206 264 VIQQLRAQLAELEA----------ELAELSARYTPNHPDVIALRAQIAALRAQLQQ-------EAQRILASLEAELEALQ 326
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1270111431 730 AKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 772
Cdd:COG3206 327 AREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
370-603 |
7.27e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.75 E-value: 7.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 370 AEEELQELRDKIakgecgnSSLMAEVESLRKRVLEMegkDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSE 449
Cdd:COG3883 14 ADPQIQAKQKEL-------SELQAELEAAQAELDAL---QAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 450 LEKLEEAFSRSKSEctqlhlnlekeknlTKDLLNELEVVKSrvkelecSEsrlekvelSLKDDLTKLKSFTvMLVDERKN 529
Cdd:COG3883 84 RREELGERARALYR--------------SGGSVSYLDVLLG-------SE--------SFSDFLDRLSALS-KIADADAD 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111431 530 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCE 603
Cdd:COG3883 134 LLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAA 207
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
366-756 |
7.76e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.14 E-value: 7.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 366 SLQKAEEELQELrDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEitKTEAQCRELKKKLQEEEHHS--KELRLEVEKL 443
Cdd:pfam12128 170 ALCDSESPLRHI-DKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPP--KSRLNRQQVEHWIRDIQAIAgiMKIRPEFTKL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 444 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVvKSRVKELECSESRLE-KVELSLKDDLTKLKSFTVM 522
Cdd:pfam12128 247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQ-LLRTLDDQWKEKRDElNGELSAADAAVAKDRSELE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 523 LVDERKNMMEKIKQEERKVD------------GLNKNFKVEQGKVMDVTEKLieeSKKLLKLKSEMEEKVYSLTKERDel 590
Cdd:pfam12128 326 ALEDQHGAFLDADIETAAADqeqlpswqseleNLEERLKALTGKHQDVTAKY---NRRRSKIKEQNNRDIAGIKDKLA-- 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 591 mgKLRSEEERSCELSCSVdllkkrLDGIEEVEREinrgrlckgseftcPEDNKIRELTLEIERLKKRLQQLEVVEGDLMK 670
Cdd:pfam12128 401 --KIREARDRQLAVAEDD------LQALESELRE--------------QLEAGKLEFNEEEYRLKSRLGELKLRLNQATA 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 671 TEDEYDQLEQ------KFRTEQDKAN--FLSQQLEEIKHQMAKNKAIEKGEAVSQeaelrhrfRMEEAKSRDLQAEVQ-- 740
Cdd:pfam12128 459 TPELLLQLENfderieRAREEQEAANaeVERLQSELRQARKRRDQASEALRQASR--------RLEERQSALDELELQlf 530
|
410
....*....|....*.
gi 1270111431 741 ALKEKIHELMNKEDQL 756
Cdd:pfam12128 531 PQAGTLLHFLRKEAPD 546
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
280-496 |
8.01e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 8.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 280 SQKVQDLTQKLREEEEKLKAitYKSKEDrqkllklEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEE 359
Cdd:COG3206 181 EEQLPELRKELEEAEAALEE--FRQKNG-------LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 360 LEETNKSLQkAEEELQELRDKIAKgecgnssLMAEVESLRKRVLE----MEGKDEEITKTEAQCR-ELKKKLQEEEHHSK 434
Cdd:COG3206 252 GPDALPELL-QSPVIQQLRAQLAE-------LEAELAELSARYTPnhpdVIALRAQIAALRAQLQqEAQRILASLEAELE 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 435 ELRLEVEKLQKRMSELEKLEEAFSRSKSEctqlHLNLEKEKNLTKDLLNELEvvkSRVKELE 496
Cdd:COG3206 324 ALQAREASLQAQLAQLEARLAELPELEAE----LRRLEREVEVARELYESLL---QRLEEAR 378
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
161-627 |
8.45e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 8.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 161 KPISELDRLEEkqketyrrmLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARK 240
Cdd:COG4717 65 KPELNLKELKE---------LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 241 EKENakRLNKLRDELVKLKsfalmlvderqmhieqlglqsQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEH 320
Cdd:COG4717 136 ALEA--ELAELPERLEELE---------------------ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 321 KASRFSQEHEEMNAKLanqeshnRQLRLKLVGLSQRIEELEETNKSLQKaEEELQELRDKIAKGE---------CGNSSL 391
Cdd:COG4717 193 ELQDLAEELEELQQRL-------AELEEELEEAQEELEELEEELEQLEN-ELEAAALEERLKEARlllliaaalLALLGL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 392 MAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSECTQLHLNL 471
Cdd:COG4717 265 GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE--ELEELLAALGLPPDLSPEELLEL 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 472 EKEKNLTKDLLNELEvvkSRVKELECSESRLEKVELSLKDDLTKLKSFT--VMLVDERKNMMEKIKQEERKVDGLNKNFK 549
Cdd:COG4717 343 LDRIEELQELLREAE---ELEEELQLEELEQEIAALLAEAGVEDEEELRaaLEQAEEYQELKEELEELEEQLEELLGELE 419
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111431 550 VEQGkvmDVTEKLIEEskKLLKLKSEMEEkvysLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDgIEEVEREINR 627
Cdd:COG4717 420 ELLE---ALDEEELEE--ELEELEEELEE----LEEELEELREELAELEAELEQLEEDGELAELLQE-LEELKAELRE 487
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
235-648 |
9.28e-05 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 46.59 E-value: 9.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 235 AYQARKEKENAKRLNKLRDELvklksfalmlvderQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKS--KEDRQKLL 312
Cdd:pfam13166 85 FTLGEESIEIQEKIAKLKKEI--------------KDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKikRKKNSALS 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 313 KLEVDFEHKASRFSQEHEEMNAKLANQEShnrqlRLKLVGLSQRIEELEETNK-SLQKAEEELQELRDKIAKGECGNS-- 389
Cdd:pfam13166 151 EALNGFKYEANFKSRLLREIEKDNFNAGV-----LLSDEDRKAALATVFSDNKpEIAPLTFNVIDFDALEKAEILIQKvi 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 390 SLMAEVESLRKR------VLEMEGKDEEITKTEAQC-----RELKKKLqeEEHHSKELRLEVEKLQKRMSELEKLEEAFS 458
Cdd:pfam13166 226 GKSSAIEELIKNpdladwVEQGLELHKAHLDTCPFCgqplpAERKAAL--EAHFDDEFTEFQNRLQKLIEKVESAISSLL 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 459 RSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLE--KVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 536
Cdd:pfam13166 304 AQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLDGL---RRALEakRKDPFKSIELDSVDAKIESINDLVASINELIAK 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 537 EERKVDGLNKnfKVEQGKV---MDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELScsvDLLKK 613
Cdd:pfam13166 381 HNEITDNFEE--EKNKAKKklrLHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELE---AQLRD 455
|
410 420 430
....*....|....*....|....*....|....*...
gi 1270111431 614 RLDGIEEVEREINR---GRLckgsEFTCPEDNKIRELT 648
Cdd:pfam13166 456 HKPGADEINKLLKAfgfGEL----ELSFNEEGKGYRII 489
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
170-496 |
1.10e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 170 EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYmNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENA--KR 247
Cdd:COG4717 93 LQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY-QELEALEAELAELPERLEELEERLEELRELEEELEEleAE 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 248 LNKLRDELV-KLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYK---------SKEDRQKLLKLEVD 317
Cdd:COG4717 172 LAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqleneleAAALEERLKEARLL 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 318 F-----------------------------------------EHKASRFSQEHEEMNAKLANQESHNRQLR--LKLVGLS 354
Cdd:COG4717 252 LliaaallallglggsllsliltiagvlflvlgllallflllAREKASLGKEAEELQALPALEELEEEELEelLAALGLP 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 355 ------------QRIEELEETNKSLQKAEEELQ--ELRDKIAK--GECGNSSLmAEVESLRKRVLEMEGKDEEITKTEAQ 418
Cdd:COG4717 332 pdlspeellellDRIEELQELLREAEELEEELQleELEQEIAAllAEAGVEDE-EELRAALEQAEEYQELKEELEELEEQ 410
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 419 CRELKKKLQE--EEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTkDLLNELEVVKSRVKELE 496
Cdd:COG4717 411 LEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA-ELLQELEELKAELRELA 489
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
394-611 |
1.25e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 46.46 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 394 EVESLRKrvlemEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSEctqlHLNLEK 473
Cdd:PRK05771 32 HIEDLKE-----ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKV--SVKSLEELIKDVEEE----LEKIEK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 474 EknlTKDLLNELEVVKSRVKELECSESRLEK-----VELSLKDDLTKLKSFTVML----VDERKNMMEKIKQEERKVDGL 544
Cdd:PRK05771 101 E---IKELEEEISELENEIKELEQEIERLEPwgnfdLDLSLLLGFKYVSVFVGTVpedkLEELKLESDVENVEYISTDKG 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1270111431 545 N--------KNFKVEQGKVM---DVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRS-EEERSCELSCSVDLL 611
Cdd:PRK05771 178 YvyvvvvvlKELSDEVEEELkklGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKElAKKYLEELLALYEYL 256
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
357-604 |
1.79e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 45.19 E-value: 1.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 357 IEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHHSKEL 436
Cdd:pfam15905 86 VQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELT-RVNELLKAKFSEDGTQKKMSSLSMELMKL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 437 RLEVEKLQKRMS--------ELEKLEEAFSRSKSECTQLH---LNLEKEKNLTKDLLNELEvvkSRVKELECSESRLEKV 505
Cdd:pfam15905 165 RNKLEAKMKEVMakqegmegKLQVTQKNLEHSKGKVAQLEeklVSTEKEKIEEKSETEKLL---EYITELSCVSEQVEKY 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 506 ELslkdDLTKLKSftvmLVDERKNMMEKIKQE-ERKVDGLNKnfkveQGKVMDVTEKLIEESKKllKLKSEMEEKVYSLT 584
Cdd:pfam15905 242 KL----DIAQLEE----LLKEKNDEIESLKQSlEEKEQELSK-----QIKDLNEKCKLLESEKE--ELLREYEEKEQTLN 306
|
250 260
....*....|....*....|
gi 1270111431 585 KERDELMGKLRSEEERSCEL 604
Cdd:pfam15905 307 AELEELKEKLTLEEQEHQKL 326
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
415-743 |
2.14e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.48 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 415 TEAQCRELKKKLQEEehhskelRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVV------ 488
Cdd:pfam05483 97 IEAELKQKENKLQEN-------RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETcarsae 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 489 KSRVKELECSESRLEKVEL--SLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGK--------VMDV 558
Cdd:pfam05483 170 KTKKYEYEREETRQVYMDLnnNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDkekqvsllLIQI 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 559 TEK---------LIEESK-------KLLKLKSE----MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGI 618
Cdd:pfam05483 250 TEKenkmkdltfLLEESRdkanqleEKTKLQDEnlkeLIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQL 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 619 EEVE----REINRGRLCKG---SEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 691
Cdd:pfam05483 330 TEEKeaqmEELNKAKAAHSfvvTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEE 409
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1270111431 692 LSQQLEEIKHQMAKNKAIEK--GEAVSQEAELRHRFRMEEAKSRDLQAEVQALK 743
Cdd:pfam05483 410 LKKILAEDEKLLDEKKQFEKiaEELKGKEQELIFLLQAREKEIHDLEIQLTAIK 463
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
393-540 |
2.62e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.15 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 393 AEVESLRKRVLeMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLE 472
Cdd:PRK12704 49 KEAEAIKKEAL-LEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELE 127
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111431 473 KEKNLTKDLLNELEVVKSRVKELECSESR---LEKVELSLKDDLTKLKsftvmlvderKNMMEKIKQEERK 540
Cdd:PRK12704 128 KKEEELEELIEEQLQELERISGLTAEEAKeilLEKVEEEARHEAAVLI----------KEIEEEAKEEADK 188
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
274-515 |
3.19e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 45.01 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 274 EQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN-------QESHNRQL 346
Cdd:PHA02562 181 QQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNlvmdiedPSAALNKL 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 347 RLKLVGLSQRIEELEETNKSLQKAEE------ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCR 420
Cdd:PHA02562 261 NTAAAKIKSKIEQFQKVIKMYEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 421 ELKKKLqeeEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNltkdllnelevvksrvkelECSES 500
Cdd:PHA02562 341 ELKNKI---STNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK-------------------TKSEL 398
|
250
....*....|....*
gi 1270111431 501 RLEKVELSLKDDLTK 515
Cdd:PHA02562 399 VKEKYHRGIVTDLLK 413
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
355-891 |
3.34e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.04 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 355 QRIEELEETNKSLQKAEEELQELRDKI----AKGECGNS---SLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQ 427
Cdd:TIGR00606 200 QKVQEHQMELKYLKQYKEKACEIRDQItskeAQLESSREivkSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 428 EEEHHSKELRLEVEKL----QKRMSELEKLEEAFSRSKS-ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL 502
Cdd:TIGR00606 280 QMEKDNSELELKMEKVfqgtDEQLNDLYHNHQRTVREKErELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRH 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 503 EkvELSLKDDLTKLKSFTVMLVDErknmMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEmeekvyS 582
Cdd:TIGR00606 360 Q--EHIRARDSLIQSLATRLELDG----FERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQE------Q 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 583 LTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRgRLCKGSEFTCPE-DNKIRELTLEIERLKKRLQQL 661
Cdd:TIGR00606 428 ADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR-ILELDQELRKAErELSKAEKNSLTETLKKEVKSL 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 662 EVVEGDLMKT---EDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEA-------------ELRHRF 725
Cdd:TIGR00606 507 QNEKADLDRKlrkLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGyfpnkkqledwlhSKSKEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 726 RMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSvlQQRF-----MEEETKNKNMGREVLNLTKELEL----SKR 796
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE--DKLFdvcgsQDEESDLERLKEEIEKSSKQRAMlagaTAV 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 797 YSRALRPSGNGRRMVdVPVASTGVQTEAVCGDAAEEETPAVFIRKSFQEEnhimsnLRQVGLKKPMERSSVLDRYPPAAN 876
Cdd:TIGR00606 665 YSQFITQLTDENQSC-CPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKS------TESELKKKEKRRDEMLGLAPGRQS 737
|
570
....*....|....*
gi 1270111431 877 ELTMRKSWIPWMRKR 891
Cdd:TIGR00606 738 IIDLKEKEIPELRNK 752
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
970-1183 |
3.40e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 44.92 E-value: 3.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 970 IPSPNVMSQKPKSAD-------------PTLGPERAMSPVTITTISREKSPeggRGAFAD--RPASPIQIMTVSTSAAPP 1034
Cdd:PLN03209 323 IPSQRVPPKESDAADgpkpvptkpvtpeAPSPPIEEEPPQPKAVVPRPLSP---YTAYEDlkPPTSPIPTPPSSSPASSK 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 1035 EI-AVS-PDSQEVPMGRTILKVTPEKQTVPTPMRKYNANANIITTEDNKIhihlgsqfKRSPGPAAAEGVSPVITVRPVn 1112
Cdd:PLN03209 400 SVdAVAkPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKP--------PTSPSPTAPTGVSPSVSSTSS- 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 1113 VTAEKEVSTGTV-----------------------LRSPRNHLSSRPGANKVTSTITITPVTTSSTRGTQSVSGQDGSSQ 1169
Cdd:PLN03209 471 VPAVPDTAPATAatdaaapppanmrplspyavyddLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQP 550
|
250
....*....|....*
gi 1270111431 1170 RPTP-TRIPMSKGMK 1183
Cdd:PLN03209 551 KPRPlSPYTMYEDLK 565
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
219-427 |
4.25e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 219 LEQERERLKKLLEQ-EKAYQARKEKEN-----------AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDL 286
Cdd:COG3206 180 LEEQLPELRKELEEaEAALEEFRQKNGlvdlseeakllLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 287 TQKLREEEeklkaitykskeDRQKLLKLEVDFEHKASRFSQEHEEMnaklanqeshnRQLRLKLVGLSQRIEEleETNKS 366
Cdd:COG3206 260 LQSPVIQQ------------LRAQLAELEAELAELSARYTPNHPDV-----------IALRAQIAALRAQLQQ--EAQRI 314
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111431 367 LQKAEEELQELRdkiakgecgnsslmAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQ 427
Cdd:COG3206 315 LASLEAELEALQ--------------AREASLQAQLAQLEARLAELPELEAELRRLEREVE 361
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
60-443 |
4.41e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.57 E-value: 4.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 60 GEDDVMASGTVKRHLKPSGESEKKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLktekTKPEVLEAHYGSAEPEKVL 139
Cdd:TIGR00618 533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL----QNITVRLQDLTEKLSEAED 608
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 140 RVLHRDAILAQEKSIGEDVYEKpiseldRLEEKQKETYrrmlEQLLLAEKchrrTVYELENEKHKHTDYMNKSDDFTNLL 219
Cdd:TIGR00618 609 MLACEQHALLRKLQPEQDLQDV------RLHLQQCSQE----LALKLTAL----HALQLTLTQERVREHALSIRVLPKEL 674
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 220 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFalmlvdERQMHIEQLGLQSQKvqdltQKLREEEEKLKA 299
Cdd:TIGR00618 675 LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEY------DREFNEIENASSSLG-----SDLAAREDALNQ 743
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 300 ITYKSKEDRQKLLKLEVDFEHKASrfsqEHEEMNAKLANQESHNRQlrlklvGLSQRIEELEETNKSLQKAEEEL-QELR 378
Cdd:TIGR00618 744 SLKELMHQARTVLKARTEAHFNNN----EEVTAALQTGAELSHLAA------EIQFFNRLREEDTHLLKTLEAEIgQEIP 813
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111431 379 DKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL 443
Cdd:TIGR00618 814 SDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
423-631 |
5.36e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.51 E-value: 5.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 423 KKKLQEEEHHSKELRlEVEKLQKRMSELE-KLEEAFSRSK---SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 498
Cdd:PLN02939 149 QARLQALEDLEKILT-EKEALQGKINILEmRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKE 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 499 ESRLEKVELSLKDDLTKLKSftvmlvderknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 578
Cdd:PLN02939 228 LDVLKEENMLLKDDIQFLKA-----------ELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYD 296
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1270111431 579 KVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLC 631
Cdd:PLN02939 297 CWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSKFS 349
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
393-801 |
5.71e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 393 AEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRM-SELEKLEEAFsrsksecTQLHLNL 471
Cdd:pfam01576 12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLaARKQELEEIL-------HELESRL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 472 EKEKNLTKDLLNELEVVKSRVKELecsESRLEKVElslkDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVE 551
Cdd:pfam01576 85 EEEEERSQQLQNEKKKMQQHIQDL---EEQLDEEE----AARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 552 QGKVMDVTEKLIEE---SKKLLKLKSEMEEKVysltkerDELMGKLRSEEERSCELscsvDLLKKRLDGieevereinrg 628
Cdd:pfam01576 158 EERISEFTSNLAEEeekAKSLSKLKNKHEAMI-------SDLEERLKKEEKGRQEL----EKAKRKLEG----------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 629 rlckgseftcpEDNKIRELTLEIErlkkrlQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAknka 708
Cdd:pfam01576 216 -----------ESTDLQEQIAELQ------AQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQIS---- 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 709 iEKGEAVSQEAELRHRfrmEEAKSRDLQAEVQALKEKIHELMN----KEDQLSQLQVDYSVLqQRFMEEETKN------- 777
Cdd:pfam01576 275 -ELQEDLESERAARNK---AEKQRRDLGEELEALKTELEDTLDttaaQQELRSKREQEVTEL-KKALEEETRSheaqlqe 349
|
410 420
....*....|....*....|....*.
gi 1270111431 778 --KNMGREVLNLTKELELSKRYSRAL 801
Cdd:pfam01576 350 mrQKHTQALEELTEQLEQAKRNKANL 375
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
85-429 |
5.99e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.18 E-value: 5.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 85 KKPLELSKEDLIQL----------LSIMEGELQA--------REDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDA 146
Cdd:PRK04863 299 RRQLAAEQYRLVEMarelaelneaESDLEQDYQAasdhlnlvQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQ 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 147 ILAQEK-SIGEDVYEKPISEL----DRLEEKQKET--YRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLL 219
Cdd:PRK04863 379 EENEARaEAAEEEVDELKSQLadyqQALDVQQTRAiqYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEL 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 220 EQERERL---KKLLEQ-EKAYQA-RK-----EKENAKrlNKLRDELVKLKSFalmlvderQMHIEQLGLQSQKVQDLTQK 289
Cdd:PRK04863 459 LSLEQKLsvaQAAHSQfEQAYQLvRKiagevSRSEAW--DVARELLRRLREQ--------RHLAEQLQQLRMRLSELEQR 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 290 LREEEEKLKAITYKSKEDRQKLLKlEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQK 369
Cdd:PRK04863 529 LRQQQRAERLLAEFCKRLGKNLDD-EDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLA 607
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 370 AEEELQELRDKIakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEE 429
Cdd:PRK04863 608 AQDALARLREQS--GEEFEDS--QDVTEYMQQLLERE---RELTVERDELAARKQALDEE 660
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
352-520 |
6.08e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 43.47 E-value: 6.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 352 GLSQRIEELEETNKSLQKAEEELQELRDKIAKGecgNSSLMAEVESLRKRVLEMEGKDEEITKteaqcrELKKKLQEEEH 431
Cdd:smart00787 148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDR---KDALEEELRQLKQLEDELEDCDPTELD------RAKEKLKKLLQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 432 HSKELRLEVEKLQKRMSELEKleeafsrsksectqlhlNLEKEKNLTKDLLNELEVVKSRVKelECSESRLEKVELsLKD 511
Cdd:smart00787 219 EIMIKVKKLEELEEELQELES-----------------KIEDLTNKKSELNTEIAEAEKKLE--QCRGFTFKEIEK-LKE 278
|
....*....
gi 1270111431 512 DLTKLKSFT 520
Cdd:smart00787 279 QLKLLQSLT 287
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
550-802 |
6.73e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 6.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 550 VEQGKVMDVTE-------KLIEESKKLLKLKsemeekvysltKERDELMGKLRSEEErscelscsvDLlkKRLDGI-EEV 621
Cdd:TIGR02168 141 IEQGKISEIIEakpeerrAIFEEAAGISKYK-----------ERRKETERKLERTRE---------NL--DRLEDIlNEL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 622 EREINRgrLCKGSEFTcpedNKIRELTLEIERLKKRLQQLEVVE--GDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI 699
Cdd:TIGR02168 199 ERQLKS--LERQAEKA----ERYKELKAELRELELALLVLRLEElrEELEELQEELKEAEEELEELTAELQELEEKLEEL 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 700 KHQMAK-------------NKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNK----EDQLSQLQVD 762
Cdd:TIGR02168 273 RLEVSEleeeieelqkelyALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEElaelEEKLEELKEE 352
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1270111431 763 YSVLQQRFMEEETKNKNMGREVLNLTKELE-LSKRYSRALR 802
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEELEEQLEtLRSKVAQLEL 393
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
474-802 |
7.32e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 7.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 474 EKNLT--KDLLNELEvvkSRVKELEcSESRLEKVELSLKDDLTKLKSFtvMLVDERKNMMEKIKQEERKVDGLNKNFkve 551
Cdd:COG1196 185 EENLErlEDILGELE---RQLEPLE-RQAEKAERYRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAEL--- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 552 qgkvmdvtEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRgrlc 631
Cdd:COG1196 256 --------EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE-----------------LARLEQDIAR---- 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 632 kgseftcpEDNKIRELTLEIERLKKRL-----------QQLEVVEGDLMKTEDEYDQLEQKFRTEQDK-ANFLSQQLEEI 699
Cdd:COG1196 307 --------LEERRRELEERLEELEEELaeleeeleeleEELEELEEELEEAEEELEEAEAELAEAEEAlLEAEAELAEAE 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 700 KHQMAKNKAI-----EKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysvLQQRFMEEE 774
Cdd:COG1196 379 EELEELAEELlealrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE---AAEEEAELE 455
|
330 340
....*....|....*....|....*...
gi 1270111431 775 TKNKNMGREVLNLTKELELSKRYSRALR 802
Cdd:COG1196 456 EEEEALLELLAELLEEAALLEAALAELL 483
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
245-750 |
7.97e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.79 E-value: 7.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 245 AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASR 324
Cdd:COG5185 106 LIKLPNYEWSADILISLLYLYKSEIVALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFGLT 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 325 FSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGEcgnssLMAEVESLRKRVLE 404
Cdd:COG5185 186 LGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELE-----DLAQTSDKLEKLVE 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 405 megKDEEI-TKTEAQCRELKKKLQEEehhSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHlNLEKEKNLTKDLLN 483
Cdd:COG5185 261 ---QNTDLrLEKLGENAESSKRLNEN---ANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA-AAEAEQELEESKRE 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 484 ELEVVKSRVKELECSESRLEKVELSLKDDLTKLksFTVMLVDERKNMMEKIKQEerkvdgLNKNFKVEQGKVMDVTEKLI 563
Cdd:COG5185 334 TETGIQNLTAEIEQGQESLTENLEAIKEEIENI--VGEVELSKSSEELDSFKDT------IESTKESLDEIPQNQRGYAQ 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 564 EESKKLLKLKSEMEEkvysltkERDELMGKLRSEEErscELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTcpeDNK 643
Cdd:COG5185 406 EILATLEDTLKAADR-------QIEELQRQIEQATS---SNEEVSKLLNELISELNKVMREADEESQSRLEEAY---DEI 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 644 IRELTLEIERLKKRLQQLE---------------VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKA 708
Cdd:COG5185 473 NRSVRSKKEDLNEELTQIEsrvstlkatleklraKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQ 552
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1270111431 709 IEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELM 750
Cdd:COG5185 553 ASNAKTDGQAANLRTAVIDELTQYLSTIESQQAREDPIPDQA 594
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
221-460 |
8.69e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.48 E-value: 8.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 221 QERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfaLMLVDERQMHIEQLGLQSQ--KVQDLT-QKLREEEEKL 297
Cdd:pfam05667 243 RKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAEL----LSSFSGSSTTDTGLTKGSRftHTEKLQfTNEAPAATSS 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 298 KAITYKSKEDRQKLLKLEVD-FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQE 376
Cdd:pfam05667 319 PPTKVETEEELQQQREEELEeLQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPD 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 377 LRDKIAKgecgnssLMAEVESLRKRVLEMEGKDEEIT----------KTEAQCREL--KKKLQE-EEHHSK------ELR 437
Cdd:pfam05667 399 AEENIAK-------LQALVDASAQRLVELAGQWEKHRvplieeyralKEAKSNKEDesQRKLEEiKELREKikevaeEAK 471
|
250 260
....*....|....*....|...
gi 1270111431 438 LEVEKLQKRMSELEKLEEAFSRS 460
Cdd:pfam05667 472 QKEELYKQLVAEYERLPKDVSRS 494
|
|
| DYN1 |
COG5245 |
Dynein, heavy chain [Cytoskeleton]; |
171-683 |
8.88e-04 |
|
Dynein, heavy chain [Cytoskeleton];
Pssm-ID: 227570 [Multi-domain] Cd Length: 3164 Bit Score: 43.82 E-value: 8.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 171 EKQKETYRRMLEqllLAEKCHRRTVYELENEKHKhtdymNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNK 250
Cdd:COG5245 2102 RKYNEYGRGMGE---LKEQLSNTVVILGVKEKNA-----DDALSGTPGERLEREVKSVFVEAPRDMLFLLEEEVRKRKGS 2173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 251 LRdelvKLKSFALMLVDERQMHIEQL-GLQSQKVQDLTQK---LREEEEKLKAITY---KSKEDRQKLLK---------- 313
Cdd:COG5245 2174 VM----KFKSSKKPAVLEAVLFVYKIkKASLREIRSFIRPpgdLCIEMEDVCDLLGfeaKIWFGEQQSLRrddfiriigk 2249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 314 --LEVDFEHKASRFsQEHEEMNAKLANQESHNRQLRL---------KLVGLSQRIEELEETNKSLQKAEEELQELRDKIA 382
Cdd:COG5245 2250 ypDEIEFDLEARRF-REARECSDPSFTGSILNRASKAcgplkrwlvRECNRSKVLEVKIPLREEEKRIDGEAFLVEDRLT 2328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 383 KGECGNSSLMAEVESLRKR----VLEMEGKdeeitktEAQCRELKKKLQEEEHHSKELRLEVEK-------LQKRMSELe 451
Cdd:COG5245 2329 LGKGLSSDLMTFKLRRRSYysldILRVHGK-------IADMDTVHKDVLRSIFVSEILINEDSEwggvfseVPKLMVEL- 2400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 452 kLEEAFSRSKSECTQLHLN-LEK--EKNLTKDLL-NELEVVKSRVKEL--ECSESRLEKVELSLKDDLT--------KLK 517
Cdd:COG5245 2401 -DGDGHPSSCLHPYIGTLGfLCRaiEFGMSFIRIsKEFRDKEIRRRQFitEGVQKIEDFKEEACSTDYGlensrirkDLQ 2479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 518 SFTVMLVDERKNMMEKIKQ--EERKVDGLNKNFKVEQ-----------GKVMDVTEKLIEESKKLLKLKS---------- 574
Cdd:COG5245 2480 DLTAVLNDPSSKIVTSQRQmyDEKKAILGSFREMEFAfglsqarregsDKIIGDAEALDEEIGRLIKEEFksnlsevkvm 2559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 575 --------EMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKR-LDGIEEV--------EREINRGRLCKGSEFT 637
Cdd:COG5245 2560 inppeivrSTVEAVFWLSEGRSGDMGSIEWKQLIQVMFVSKVLGCETEiPDALEKLvsgplfvhEKALNALKACGSLFLW 2639
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 1270111431 638 CPEDNKIRELTLEIE-------------RLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 683
Cdd:COG5245 2640 VLARYLLAKLMLSISnmeqtdeiavllhNLKKSRKEIEEEESESMEIEDRIDALKSEYN 2698
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
420-697 |
9.16e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.38 E-value: 9.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 420 RELKKKLQEEEHHskELRLEVEKLQKRMSELEKLEEAFSRSKSEctQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 499
Cdd:PRK05771 34 EDLKEELSNERLR--KLRSLLTKLSEALDKLRSYLPKLNPLREE--KKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 500 SRLE---KVELSLKDDLTKLKSFTVMLVDERKNmmekikqeerkvdglnKNFKVEQGKV-MDVTE--KLIEESKKLLKLK 573
Cdd:PRK05771 110 SELEneiKELEQEIERLEPWGNFDLDLSLLLGF----------------KYVSVFVGTVpEDKLEelKLESDVENVEYIS 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 574 SEMEEKVYSLTKERdELMGKLRSEEERscelscsVDLLKKRLDGIEEVEREINRgrlckgseftcpEDNKIRELTLEIER 653
Cdd:PRK05771 174 TDKGYVYVVVVVLK-ELSDEVEEELKK-------LGFERLELEEEGTPSELIRE------------IKEELEEIEKERES 233
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1270111431 654 LKKRLQQLEVVEGDLMKTEDEYdqLEQkfrtEQDKANFLSQQLE 697
Cdd:PRK05771 234 LLEELKELAKKYLEELLALYEY--LEI----ELERAEALSKFLK 271
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
241-539 |
1.03e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 42.59 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 241 EKENAKRLNKLRDELVKLKsfalmlvDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEH 320
Cdd:COG1340 10 LEELEEKIEELREEIEELK-------EKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 321 KASRFSQEHEEMNaKLANQESHNRQLRLKLVGLSQRIEELEET--NKSLQKAEEelQELRDKIAkgecgnsslmaEVESL 398
Cdd:COG1340 83 LNEKLNELREELD-ELRKELAELNKAGGSIDKLRKEIERLEWRqqTEVLSPEEE--KELVEKIK-----------ELEKE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 399 RKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEafsrSKSECTQLHLNLEKEKNL 477
Cdd:COG1340 149 LEKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELyKEADE----LRKEADELHKEIVEAQEK 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111431 478 TKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFtvmlvDERKNMMEKIKQEER 539
Cdd:COG1340 225 ADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEELE-----EKAEEIFEKLKKGEK 281
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
396-757 |
1.18e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.96 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 396 ESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEK 475
Cdd:pfam07888 38 ECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 476 NLtkdLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLV-------DERKNMMEKIKQEERKVDGLNKNF 548
Cdd:pfam07888 118 DA---LLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGaqrkeeeAERKQLQAKLQQTEEELRSLSKEF 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 549 KVEQGKvmdvtekLIEESKKLLKLKSEMEEKVYSLTK------ERDELMGKLRSEEERSCELSCSVDLLKKRLDGI---- 618
Cdd:pfam07888 195 QELRNS-------LAQRDTQVLQLQDTITTLTQKLTTahrkeaENEALLEELRSLQERLNASERKVEGLGEELSSMaaqr 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 619 EEVEREINRGRLcKGSEFTcpedNKIRELTLEIERLKKRLQQLEvvEGDLMKTEDEYDQLEQKFRTEQDKANFLSQ---Q 695
Cdd:pfam07888 268 DRTQAELHQARL-QAAQLT----LQLADASLALREGRARWAQER--ETLQQSAEADKDRIEKLSAELQRLEERLQEermE 340
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111431 696 LEEIKHQMAKNK---AIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLS 757
Cdd:pfam07888 341 REKLEVELGREKdcnRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVA 405
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
416-704 |
1.22e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 416 EAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEE-AFSRSKSECTQLHL-NLEKEKNLTKDLLNELEVVKSRVK 493
Cdd:COG4913 616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEySWDEIDVASAEREIaELEAELERLDASSDDLAALEEQLE 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 494 ELECSESRLEKVELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLNKNFKVEQgkvmdvtEKLIEESKKLLKLK 573
Cdd:COG4913 696 ELEAELEELEEELDELKGEIGRLEK-------ELEQAEEELDELQDRLEAAEDLARLEL-------RALLEERFAAALGD 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 574 SEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRgrlckgsEFTCPednkIRELTLEIER 653
Cdd:COG4913 762 AVERELRENLEERIDALRARLNRAEEE-----------------LERAMRAFNR-------EWPAE----TADLDADLES 813
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111431 654 L---KKRLQQLEvvEGDLMKTEDEYDQLEQKFrTEQDKANFLS---QQLEEIKHQMA 704
Cdd:COG4913 814 LpeyLALLDRLE--EDGLPEYEERFKELLNEN-SIEFVADLLSklrRAIREIKERID 867
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
269-654 |
1.39e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.02 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 269 RQMHIEQLGLQsqkvqdltqklREEEEKLKAityKSKEDRQKLLKLEVDFehkaSRFSQEHEEMnAKLANQESHNRQLRL 348
Cdd:PRK04863 784 REKRIEQLRAE-----------REELAERYA---TLSFDVQKLQRLHQAF----SRFIGSHLAV-AFEADPEAELRQLNR 844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 349 KLVGLSQRIEELEETNKS----LQKAEEELQELRDKIakgecGNSSLMAEvESLRKRVLEMEgkdEEITKTE-------- 416
Cdd:PRK04863 845 RRVELERALADHESQEQQqrsqLEQAKEGLSALNRLL-----PRLNLLAD-ETLADRVEEIR---EQLDEAEeakrfvqq 915
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 417 --AQCRELKK---KLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRsksectQLHLNLEKEKN-LTKDllNEL- 485
Cdd:PRK04863 916 hgNALAQLEPivsVLQSDPEQFEQLKQDYQQAQQTQRDAKQqafaLTEVVQR------RAHFSYEDAAEmLAKN--SDLn 987
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 486 EVVKSRVKELECSESRLeKVELSLKDD--------LTKLKS-FTVM--LVDERKNMMEKI---------KQEERKVDGLN 545
Cdd:PRK04863 988 EKLRQRLEQAEQERTRA-REQLRQAQAqlaqynqvLASLKSsYDAKrqMLQELKQELQDLgvpadsgaeERARARRDELH 1066
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 546 KNFKVEQGKvmdvteklieeskkllklKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK------RLDGIE 619
Cdd:PRK04863 1067 ARLSANRSR------------------RNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAgwcavlRLVKDN 1128
|
410 420 430
....*....|....*....|....*....|....*
gi 1270111431 620 EVEREINRGRLckgSEFTCPEDNKIRELTLEIERL 654
Cdd:PRK04863 1129 GVERRLHRREL---AYLSADELRSMSDKALGALRL 1160
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
349-603 |
1.44e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.80 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 349 KLVGLSQRIEELE--ETNKSLQKAEEELQEL--RDKIAKGECGNSSLM---AEVESLRKRVLEMEGKDEEITKTEAQCRE 421
Cdd:pfam17380 282 KAVSERQQQEKFEkmEQERLRQEKEEKAREVerRRKLEEAEKARQAEMdrqAAIYAEQERMAMERERELERIRQEERKRE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 422 LKKKLQEE-----EHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELE 496
Cdd:pfam17380 362 LERIRQEEiameiSRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 497 CSESR-LEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE 575
Cdd:pfam17380 442 EERAReMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKE 521
|
250 260
....*....|....*....|....*...
gi 1270111431 576 MEEKVYSLTKERDelmgKLRSEEERSCE 603
Cdd:pfam17380 522 MEERQKAIYEEER----RREAEEERRKQ 545
|
|
| HAP1_N |
pfam04849 |
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ... |
241-380 |
1.48e-03 |
|
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.
Pssm-ID: 461455 [Multi-domain] Cd Length: 309 Bit Score: 42.32 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 241 EKENakrlNKLRDELVKLKSFALMLVDERQMHI----EQLGLQSQKVQDLTQKL-REEEEKLKaitykSKEDRQKLLKLE 315
Cdd:pfam04849 177 EEEN----LKLRSEASHLKTETDTYEEKEQQLMsdcvEQLSEANQQMAELSEELaRKMEENLR-----QQEEITSLLAQI 247
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111431 316 VDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEEtnkSLQKAEEELQELRDK 380
Cdd:pfam04849 248 VDLQHKCKELGIENEELQQHLQASKEAQRQLTSELQELQDRYAECLG---MLHEAQEELKELRKK 309
|
|
| ADIP |
pfam11559 |
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ... |
440-544 |
1.49e-03 |
|
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.
Pssm-ID: 463295 [Multi-domain] Cd Length: 151 Bit Score: 40.38 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 440 VEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSf 519
Cdd:pfam11559 44 LQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKTQLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKN- 122
|
90 100
....*....|....*....|....*
gi 1270111431 520 tvMLVDERKNMMEKIKQEERKVDGL 544
Cdd:pfam11559 123 --ALQQIKTQFAHEVKKRDREIEKL 145
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
221-758 |
1.64e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.89 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 221 QERERLKKLLEQEKAYQARKEKENAK------RLNKLRDELVKLKSFALMLVDERQMHIEQL-------GLQSQKVQDLT 287
Cdd:pfam10174 216 HRRNQLQPDPAKTKALQTVIEMKDTKisslerNIRDLEDEVQMLKTNGLLHTEDREEEIKQMevykshsKFMKNKIDQLK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 288 QKLREEEEKLKAITYK-----------------------SKEDRQKLLKLEVD-----------FEHKASRFSQEHEEMN 333
Cdd:pfam10174 296 QELSKKESELLALQTKletltnqnsdckqhievlkesltAKEQRAAILQTEVDalrlrleekesFLNKKTKQLQDLTEEK 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 334 AKLANQESHNRQL----RLKLVGLSQRIEELEEtnkSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKD 409
Cdd:pfam10174 376 STLAGEIRDLKDMldvkERKINVLQKKIENLQE---QLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 410 EEItkTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVK 489
Cdd:pfam10174 453 ERL--KEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKK 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 490 SRVKELEcsesrlekvelslkddlTKLKSFTVMLVDERKN--MMEKIKQEERKVdglnKNFKVEQGKVMDVTEKLIE--- 564
Cdd:pfam10174 531 EECSKLE-----------------NQLKKAHNAEEAVRTNpeINDRIRLLEQEV----ARYKEESGKAQAEVERLLGilr 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 565 --ESKKLLKLK--SEMEEKVYSLTKERDELMGKLRSEEErscelscsvdllKKRLDGIEEVEreinRGRLCKGSEFTCPE 640
Cdd:pfam10174 590 evENEKNDKDKkiAELESLTLRQMKEQNKKVANIKHGQQ------------EMKKKGAQLLE----EARRREDNLADNSQ 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 641 DNKIRELTLEIERLKkrlQQLEVVEGDLMKTED---EYDQLEQKFRTEQDKanflsqQLEEI--KHQMAKNKAIEKGEAV 715
Cdd:pfam10174 654 QLQLEELMGALEKTR---QELDATKARLSSTQQslaEKDGHLTNLRAERRK------QLEEIleMKQEALLAAISEKDAN 724
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 1270111431 716 SQEAELrhrfrmEEAKSRDLQAEVQALKEKIHELMNKEDQLSQ 758
Cdd:pfam10174 725 IALLEL------SSSKKKKTQEEVMALKREKDRLVHQLKQQTQ 761
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
353-496 |
1.99e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.88 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 353 LSQRI----EELEETNKslqkaeeELQELRDKIAKGECGNSSLMAEVESLRKRVLEME-----------GKDEEITKTEA 417
Cdd:PRK09039 44 LSREIsgkdSALDRLNS-------QIAELADLLSLERQGNQDLQDSVANLRASLSAAEaersrlqallaELAGAGAAAEG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 418 QCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRSKSEctqlhlnlEKEKNLT-KDLLNELEV-VKSR 491
Cdd:PRK09039 117 RAGELAQELDSEKQVSARALAQVELLNQQIAALRRqlaaLEAALDASEKR--------DRESQAKiADLGRRLNVaLAQR 188
|
....*
gi 1270111431 492 VKELE 496
Cdd:PRK09039 189 VQELN 193
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
609-795 |
2.88e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.21 E-value: 2.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 609 DLLKKRLDG----IEEVEREINRgrLCKGSEFTCPEDNKIRELT-LEiERLKKRLQQLEVVEGDLmkteDEYDQLEQKFR 683
Cdd:PRK11281 83 EQLKQQLAQapakLRQAQAELEA--LKDDNDEETRETLSTLSLRqLE-SRLAQTLDQLQNAQNDL----AEYNSQLVSLQ 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 684 TEQDKA-NFLS---QQLEEIKHQMAKNKAIEKGEAVSQEAELrhrfrmeeaksrdlQAEVQALKEKIhELMNKE----DQ 755
Cdd:PRK11281 156 TQPERAqAALYansQRLQQIRNLLKGGKVGGKALRPSQRVLL--------------QAEQALLNAQN-DLQRKSlegnTQ 220
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1270111431 756 LS---QLQVDYSVLQQRFMEEETKNKnmgREVLNlTKELELSK 795
Cdd:PRK11281 221 LQdllQKQRDYLTARIQRLEHQLQLL---QEAIN-SKRLTLSE 259
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
248-780 |
3.13e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.96 E-value: 3.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 248 LNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKedRQKLLKLEVdfEHKASRFSQ 327
Cdd:TIGR01612 673 IDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENK--KNELLDIIV--EIKKHIHGE 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 328 EHEEMNAKLANQESHNRQLrlklvglSQRIEELEETNKSLQKAEEELQELR----DKIAKGECGNSSLMAEVESLRKRVL 403
Cdd:TIGR01612 749 INKDLNKILEDFKNKEKEL-------SNKINDYAKEKDELNKYKSKISEIKnhynDQINIDNIKDEDAKQNYDKSKEYIK 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 404 EMEGKDEEITKTEAQCRELKKKLQEEEhhSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNL-EKEKNLTKDLL 482
Cdd:TIGR01612 822 TISIKEDEIFKIINEMKFMKDDFLNKV--DKFINFENNCKEKIDSEHEQFAELTNKIKAEISDDKLNDyEKKFNDSKSLI 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 483 NE---------------------LEVVKSRVKELECSESRLEKVELSLKDDLTKLKS-----------FTVMLVDeRKNM 530
Cdd:TIGR01612 900 NEinksieeeyqnintlkkvdeyIKICENTKESIEKFHNKQNILKEILNKNIDTIKEsnlieksykdkFDNTLID-KINE 978
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 531 MEKIKQE-------------------------ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTK 585
Cdd:TIGR01612 979 LDKAFKDaslndyeaknnelikyfndlkanlgKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIID 1058
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 586 ERDELMGKlrseeerscelscSVDLLKKRLdgIEEVEREInrgrlckgSEFtcpedNKIReltleiERLKKRLQQLEVVE 665
Cdd:TIGR01612 1059 EIEKEIGK-------------NIELLNKEI--LEEAEINI--------TNF-----NEIK------EKLKHYNFDDFGKE 1104
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 666 GDLmKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK-----NKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQ 740
Cdd:TIGR01612 1105 ENI-KYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENyideiKAQINDLEDVADKAISNDDPEEIEKKIENIVTKID 1183
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 1270111431 741 AlKEKIHELMNK-EDQLSQLQVDYSVLqqrfmeEETKNKNM 780
Cdd:TIGR01612 1184 K-KKNIYDEIKKlLNEIAEIEKDKTSL------EEVKGINL 1217
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
643-800 |
3.26e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 643 KIRELTLEIERLKKRLQQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK--NKAIEKGEA-- 714
Cdd:COG4942 42 ELAALKKEEKALLKQLAALErriaALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllRALYRLGRQpp 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 715 ----VSQE--AELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLT 788
Cdd:COG4942 122 lallLSPEdfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL 201
|
170
....*....|..
gi 1270111431 789 KELELSKRYSRA 800
Cdd:COG4942 202 ARLEKELAELAA 213
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
500-763 |
4.35e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.45 E-value: 4.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 500 SRLEKVE-LSLKDD----LTKLKSFTVMLVDErknmmekIKQEErkvdglnKNFKVEqgkvmDVTEKLIEESKKLLKLKS 574
Cdd:PRK05771 4 VRMKKVLiVTLKSYkdevLEALHELGVVHIED-------LKEEL-------SNERLR-----KLRSLLTKLSEALDKLRS 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 575 EMEEKvySLTKERDELMGKLRSEEerscelscsvdLLKKRLDGIEEVEREINRgrlckgseftcpEDNKIRELTLEIERL 654
Cdd:PRK05771 65 YLPKL--NPLREEKKKVSVKSLEE-----------LIKDVEEELEKIEKEIKE------------LEEEISELENEIKEL 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 655 KKRLQQLEVVEG-DL-MKTEDEYDQLEQKF-RTEQDKANFLSQQLEEIKHQMAKNK--------AIEKGEAVSQEAELR- 722
Cdd:PRK05771 120 EQEIERLEPWGNfDLdLSLLLGFKYVSVFVgTVPEDKLEELKLESDVENVEYISTDkgyvyvvvVVLKELSDEVEEELKk 199
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111431 723 HRFR-------------MEEAKSR--DLQAEVQALKEKIHELMNKEDQLSQLQVDY 763
Cdd:PRK05771 200 LGFErleleeegtpselIREIKEEleEIEKERESLLEELKELAKKYLEELLALYEY 255
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
156-382 |
4.86e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 40.67 E-value: 4.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 156 EDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNL---LEQERERLKKLLEQ 232
Cdd:pfam00038 35 SELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYEDELNLrtsAENDLVGLRKDLDE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 233 ekAYQARKEKENakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQ----SQKVQDLTQKLREEEEKLKAITYKSKED- 307
Cdd:pfam00038 115 --ATLARVDLEA--KIESLKEELAFLKKNHEEEVRELQAQVSDTQVNvemdAARKLDLTSALAEIRAQYEEIAAKNREEa 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 308 ----RQKL--LKLEVDFEHKASRFSQEH-EEMNAKLANQESHNRQLRLKLVGLSQRIEELEET--------NKSLQKAEE 372
Cdd:pfam00038 191 eewyQSKLeeLQQAAARNGDALRSAKEEiTELRRTIQSLEIELQSLKKQKASLERQLAETEERyelqladyQELISELEA 270
|
250
....*....|
gi 1270111431 373 ELQELRDKIA 382
Cdd:pfam00038 271 ELQETRQEMA 280
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
268-429 |
4.96e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.48 E-value: 4.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 268 ERQMHIEQLGLQSQKVQDLTQKLREE---EEKLKAITYKSKEDRQKllklEVDFEHKASRFSQEHEEMNAKLANQESHNR 344
Cdd:COG3096 506 SQQALAQRLQQLRAQLAELEQRLRQQqnaERLLEEFCQRIGQQLDA----AEELEELLAELEAQLEELEEQAAEAVEQRS 581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 345 QLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKK 424
Cdd:COG3096 582 ELRQQLEQLRARIKELAARAPAWLAAQDALERLREQS--GEALADS--QEVTAAMQQLLERE---REATVERDELAARKQ 654
|
....*
gi 1270111431 425 KLQEE 429
Cdd:COG3096 655 ALESQ 659
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
526-753 |
5.03e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 5.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 526 ERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEM---EEKVYSLTKERDELMGKLRSEEERsc 602
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalEAELAELEKEIAELRAELEAQKEE-- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 603 elscsvdlLKKRLDGIEEVEREINRGRLCKGSEFTcpedNKIRELTLEIERLKKRLQQLEvvegDLMKTEDEYDQLEQKF 682
Cdd:COG4942 106 --------LAELLRALYRLGRQPPLALLLSPEDFL----DAVRRLQYLKYLAPARREQAE----ELRADLAELAALRAEL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111431 683 RTEQDKANFLSQQLEEIKHQMAKNKAiekgEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKE 753
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
281-452 |
5.92e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 281 QKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFsqehEEMNAKLANQEShNRQLRlklvGLSQRIEEL 360
Cdd:COG1579 31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI----KKYEEQLGNVRN-NKEYE----ALQKEIESL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 361 EetnKSLQKAEEELQElrdkiakgecgnssLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEhhsKELRLEV 440
Cdd:COG1579 102 K---RRISDLEDEILE--------------LMERIEELEEELAELE---AELAELEAELEEKKAELDEEL---AELEAEL 158
|
170
....*....|..
gi 1270111431 441 EKLQKRMSELEK 452
Cdd:COG1579 159 EELEAEREELAA 170
|
|
| COG0610 |
COG0610 |
Type I site-specific restriction-modification system, R (restriction) subunit and related ... |
223-443 |
6.01e-03 |
|
Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ... [Defense mechanisms];
Pssm-ID: 440375 [Multi-domain] Cd Length: 936 Bit Score: 41.01 E-value: 6.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 223 RERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKlkaITY 302
Cdd:COG0610 706 TEKLEALDEAVERFLGDEEAR--KEFKKLFKELSRLYNLLSPDDEFGDLELEKYRDDVSFYLALRAKLRKLGEK---LDL 780
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 303 KSKEDR-QKLLKLEVDFEHKASRfsqehEEMNAKLANQEShnrqlrlklvgLSQRIEEL-EETNK---SLQKAEEELQEL 377
Cdd:COG0610 781 KEYEEKiRQLLDEAIDLERKEIK-----PRIKQNPVQYRK-----------FSELLEEIiEEYNNgalDADEVLEELEEL 844
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111431 378 RDKIAKGE--CGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL 443
Cdd:COG0610 845 AKEVKEEEerAEEEGLNEEELAFYDALAENLGDEKLKELAKELDDLLKKNVTVDWRKRESVRAKLRDA 912
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
175-760 |
6.80e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 40.97 E-value: 6.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 175 ETYRRMLEQLLLAEKCHRRTVYELEN------EKHKH-TDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAK- 246
Cdd:PTZ00440 546 KYYLQSIETLIKDEKLKRSMKNDIKNkikyieENVDHiKDIISLNDEIDNIIQQIEELINEALFNKEKFINEKNDLQEKv 625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 247 --RLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVD--FEHKA 322
Cdd:PTZ00440 626 kyILNKFYKGDLQELLDELSHFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMKSDNIDNIIKNLKKELQnlLSLKE 705
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 323 SRFSQEHEEMNAKLANqeSHNrQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRV 402
Cdd:PTZ00440 706 NIIKKQLNNIEQDISN--SLN-QYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNTYEEF 782
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 403 LE----MEGKDEEITKTEAQCRELKKKLQEE-----------EHHSKELRLEVEKLQKRMSE------LEKLEEAFSRSK 461
Cdd:PTZ00440 783 LQykdtILNKENKISNDINILKENKKNNQDLlnsyniliqklEAHTEKNDEELKQLLQKFPTedenlnLKELEKEFNENN 862
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 462 S-------ECTQLHLNLEKEKNLTkDLLNELEVVKSRVKELECSESRLEKVelsLKDDLTKLKSFTVMLVDERKNMMEKI 534
Cdd:PTZ00440 863 QivdniikDIENMNKNINIIKTLN-IAINRSNSNKQLVEHLLNNKIDLKNK---LEQHMKIINTDNIIQKNEKLNLLNNL 938
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 535 KQEERKV-----DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEmeekvySLTKERDELMgKLRSEEERsceLSCSVD 609
Cdd:PTZ00440 939 NKEKEKIekqlsDTKINNLKMQIEKTLEYYDKSKENINGNDGTHLE------KLDKEKDEWE-HFKSEIDK---LNVNYN 1008
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 610 LLKKRLDGI-----EEVEREINRGRLCKGSEFTCPEDNKIRELtleiERLKKRLQQLEVVEgDLMKTED-----EYDQLE 679
Cdd:PTZ00440 1009 ILNKKIDDLikkqhDDIIELIDKLIKEKGKEIEEKVDQYISLL----EKMKTKLSSFHFNI-DIKKYKNpkikeEIKLLE 1083
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 680 QKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELrhrfrmeEAKSRDLQAEVQALKEKIHELMNKEDQLSQL 759
Cdd:PTZ00440 1084 EKVEALLKKIDENKNKLIEIKNKSHEHVVNADKEKNKQTEHY-------NKKKKSLEKIYKQMEKTLKELENMNLEDITL 1156
|
.
gi 1270111431 760 Q 760
Cdd:PTZ00440 1157 N 1157
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
396-527 |
7.29e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.61 E-value: 7.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 396 ESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLE-------VEKLQKRMSELEKLEEAFSRSKSECTqlh 468
Cdd:COG2433 392 EEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEleekderIERLERELSEARSEERREIRKDREIS--- 468
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111431 469 lNLEKEknlTKDLLNELEVVKSRVKELECSESRLEKV-ELSLKDDLT---KLKSFT---VMLVDER 527
Cdd:COG2433 469 -RLDRE---IERLERELEEERERIEELKRKLERLKELwKLEHSGELVpvkVVEKFTkeaIRRLEEE 530
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
197-521 |
7.45e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 40.33 E-value: 7.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 197 ELENEKHKHTDYMNKSDDFTNLLEQERErlkklLEQEKAYQarkEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQL 276
Cdd:COG5185 237 GFQDPESELEDLAQTSDKLEKLVEQNTD-----LRLEKLGE---NAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIK 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 277 GLQSQK---------VQDLTQKLREEEEKLKAIT------YKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 341
Cdd:COG5185 309 KATESLeeqlaaaeaEQELEESKRETETGIQNLTaeieqgQESLTENLEAIKEEIENIVGEVELSKSSEELDSFKDTIES 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 342 HNRQLRLKLVGLSQRIEELEET-NKSLQKAEEELQELRDKIAKgecGNSSLMAEVESLRKRVLEMEGKDEEItkteaqcr 420
Cdd:COG5185 389 TKESLDEIPQNQRGYAQEILATlEDTLKAADRQIEELQRQIEQ---ATSSNEEVSKLLNELISELNKVMREA-------- 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 421 ELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNEL-EVVKSRVKELECSE 499
Cdd:COG5185 458 DEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVaESLKDFMRARGYAH 537
|
330 340
....*....|....*....|..
gi 1270111431 500 SRLEKVELSLKDDLTKLKSFTV 521
Cdd:COG5185 538 ILALENLIPASELIQASNAKTD 559
|
|
| PRK00106 |
PRK00106 |
ribonuclease Y; |
326-494 |
7.97e-03 |
|
ribonuclease Y;
Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 40.24 E-value: 7.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 326 SQEHEEMNAKLANQESHNrqLRLKLVGLSQRI-EELEETNKSLQK-----AEEELQELRDKIAKGECGNSSLMAEVES-L 398
Cdd:PRK00106 29 AKEAAELTLLNAEQEAVN--LRGKAERDAEHIkKTAKRESKALKKellleAKEEARKYREEIEQEFKSERQELKQIESrL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 399 RKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSECTQLHLnLEKEKNLT 478
Cdd:PRK00106 107 TERATSLDRKDENLSSKEKTLESKEQSLTDKSKHIDEREEQVEKLEEQ--KKAELERVAALSQAEAREIIL-AETENKLT 183
|
170
....*....|....*.
gi 1270111431 479 KDLLNELEVVKSRVKE 494
Cdd:PRK00106 184 HEIATRIREAEREVKD 199
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
222-463 |
9.56e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.11 E-value: 9.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 222 ERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKL---- 297
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMamer 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 298 -KAITYKSKEDRQK-------------------LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQ-R 356
Cdd:pfam17380 347 eRELERIRQEERKRelerirqeeiameisrmreLERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQiR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 357 IEELEETNKSLQKAEE----ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCR--------ELKK 424
Cdd:pfam17380 427 AEQEEARQREVRRLEEerarEMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkilekeleERKQ 506
|
250 260 270
....*....|....*....|....*....|....*....
gi 1270111431 425 KLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSE 463
Cdd:pfam17380 507 AMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQ 545
|
|
| Fez1 |
pfam06818 |
Fez1; This family represents the eukaryotic Fez1 protein. Fez1 contains a leucine-zipper ... |
328-449 |
9.97e-03 |
|
Fez1; This family represents the eukaryotic Fez1 protein. Fez1 contains a leucine-zipper region with similarity to the DNA-binding domain of the cAMP-responsive activating-transcription factor 5. There is evidence that Fez1 inhibits cancer cell growth through regulation of mitosis, and that its alterations result in abnormal cell growth. Note that some family members contain more than one copy of this region.
Pssm-ID: 462015 [Multi-domain] Cd Length: 198 Bit Score: 38.83 E-value: 9.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111431 328 EHEEMNAKLANQESHNRQLRLKLvglSQRIEELEETNKSLQKAEEELQELRDKIAKGEcgnsslmAEVESLRKrvlEMEG 407
Cdd:pfam06818 39 QLRELRAKLEEKEEQIQELEDSL---RSKTLELEVCENELQRKKNEAELLREKVGKLE-------EEVSGLRE---ALSD 105
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1270111431 408 KDEEITKTEAQCRELKKKLQEEEhHSKELRLEVEKLQKRMSE 449
Cdd:pfam06818 106 VSPSGYESVYESDEAKEQRQEEA-DLGSLRREVERLRAELRE 146
|
|
| |
