|
Name |
Accession |
Description |
Interval |
E-value |
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
74-255 |
3.71e-72 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 238.27 E-value: 3.71e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 74 ELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYE----KPIS 149
Cdd:pfam09727 1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 150 ELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 229
Cdd:pfam09727 81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160
|
170 180
....*....|....*....|....*.
gi 1270111363 230 AKRLNKLRDELVKLKSFALMLVDERQ 255
Cdd:pfam09727 161 KKLLEKLEEELSKQKQIALLLVKERK 186
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
205-738 |
5.06e-22 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 102.83 E-value: 5.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 205 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLKA 284
Cdd:PRK03918 188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLE---GSKRKLEEKIRE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 285 ITYKSKEDRQKLLKLEV---------DFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKA 355
Cdd:PRK03918 264 LEERIEELKKEIEELEEkvkelkelkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 356 EEELQELRDKIAKGECGNS------SLMAEVESLRKRVlemegKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQ 429
Cdd:PRK03918 344 KKKLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 430 KRMSELEKLEEAFSRSKSEC--TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVM 507
Cdd:PRK03918 419 KEIKELKKAIEELKKAKGKCpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 508 --LVDERKNM--------MEKIKQEERKVDGLNKNFKVEQGKVMDVtEKLIEESKKLLKLKSEMEEKVYSLTKERDELMG 577
Cdd:PRK03918 499 keLAEQLKELeeklkkynLEELEKKAEEYEKLKEKLIKLKGEIKSL-KKELEKLEELKKKLAELEKKLDELEEELAELLK 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 578 KLRSEEERScelscsVDLLKKRLDGIEEVEREINRgrlCKGSEFTCPEdnKIRELTLEIERLKKRLQQLEVVEGDLMKTE 657
Cdd:PRK03918 578 ELEELGFES------VEELEERLKELEPFYNEYLE---LKDAEKELER--EEKELKKLEEELDKAFEELAETEKRLEELR 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 658 DEYDQLEQKFRTEQ---------DKANFLSQQLEEIKHQMAKNKAIEKG-EAVSQEAELRHRFRMEEAKSRDLQAEVQAL 727
Cdd:PRK03918 647 KELEELEKKYSEEEyeelreeylELSRELAGLRAELEELEKRREEIKKTlEKLKEELEEREKAKKELEKLEKALERVEEL 726
|
570
....*....|.
gi 1270111363 728 KEKIHELMNKE 738
Cdd:PRK03918 727 REKVKKYKALL 737
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
32-763 |
1.03e-16 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 86.35 E-value: 1.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 32 PSEDAKKNKANRKGEDDVMasgtvkRHLKPSGESEKKTKKPLELSKEDLIQLLSIMEgelQAREDVIHMLKTEKTKPEVL 111
Cdd:PTZ00121 1051 DIDGNHEGKAEAKAHVGQD------EGLKPSYKDFDFDAKEDNRADEATEEAFGKAE---EAKKTETGKAEEARKAEEAK 1121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 112 EAHYGSAEPEKVLRVlhRDAILAQEKSIGEDvyEKPISELDRLEEKQKETYRRMLEQLLLAEKCHR----RTVYELEN-E 186
Cdd:PTZ00121 1122 KKAEDARKAEEARKA--EDARKAEEARKAED--AKRVEIARKAEDARKAEEARKAEDAKKAEAARKaeevRKAEELRKaE 1197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 187 KHKHTDYMNKSDDFTNLLEQER-ERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQS 265
Cdd:PTZ00121 1198 DARKAEAARKAEEERKAEEARKaEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA 1277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 266 QKVQDLtqklREEEEKLKAITYKSKEDRQKllkleVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLvglsqrieel 345
Cdd:PTZ00121 1278 RKADEL----KKAEEKKKADEAKKAEEKKK-----ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA---------- 1338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 346 EETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEaqcrELKKKLQEEEHHSKELRL-- 423
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD----EAKKKAEEDKKKADELKKaa 1414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 424 ----EVEKLQKRMSELEKLEEAfsRSKSECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKD 496
Cdd:PTZ00121 1415 aakkKADEAKKKAEEKKKADEA--KKKAEEAKKADEAKKkaeEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA 1492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 497 DLTKLKSFTVMLVDERKNMMEKIK--QEERKVDGLNKnfkVEQGKVMDVTEKlIEESKKLLKLKSEMEEKVYSLTKERDE 574
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKkaEEAKKADEAKK---AEEAKKADEAKK-AEEKKKADELKKAEELKKAEEKKKAEE 1568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 575 lmgKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIREltleiERLKKRLQQLEVVEGDLM 654
Cdd:PTZ00121 1569 ---AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA-----EELKKAEEEKKKVEQLKK 1640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 655 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHEL 734
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEE 1720
|
730 740
....*....|....*....|....*....
gi 1270111363 735 MNKEDQLSQLQVDysvlQQRFMEEETKNK 763
Cdd:PTZ00121 1721 LKKAEEENKIKAE----EAKKEAEEDKKK 1745
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
141-655 |
9.42e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.80 E-value: 9.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 141 EDVYEKPISELDRLEEKQK--ETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQE 218
Cdd:PRK03918 213 SSELPELREELEKLEKEVKelEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 219 KAYQARKE--KENAKRLNKLRDELVKLKSfalmLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKL 296
Cdd:PRK03918 293 EEYIKLSEfyEEYLDELREIEKRLSRLEE----EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 297 LKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQElrdkiAKGECGN--- 373
Cdd:PRK03918 369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK-----AKGKCPVcgr 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 374 -----------SSLMAEVESLRKRVLEMEGKDEEITKTEaqcRELKKKLQEEEHHSKELRL--EVEKLQKRMSE--LEKL 438
Cdd:PRK03918 444 elteehrkellEEYTAELKRIEKELKEIEEKERKLRKEL---RELEKVLKKESELIKLKELaeQLKELEEKLKKynLEEL 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 439 EEAfSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEK 518
Cdd:PRK03918 521 EKK-AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEP 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 519 IKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEkvysLTKERDELMGKLRSEE-----ERSCELSCSV 593
Cdd:PRK03918 600 FYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE----LRKELEELEKKYSEEEyeelrEEYLELSREL 675
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 594 DLLKKRLDGIEEVEREINrgrlcKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMK 655
Cdd:PRK03918 676 AGLRAELEELEKRREEIK-----KTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKK 732
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
329-768 |
1.16e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.42 E-value: 1.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 329 RQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEIT-------KTE 401
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEelekeleSLE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 402 AQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEE------AFSRSKSECTQLHLNLEKEKNltkDLLNELEVVKS 475
Cdd:PRK03918 252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEkaeeyiKLSEFYEEYLDELREIEKRLS---RLEEEINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 476 RVKELECSESRLEKVELSLKDDLTKLksftvMLVDERKNMMEKIKQEERKVDGLNKNFKVEQgkvmdvTEKLIEESKKLL 555
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRL-----EELEERHELYEEAKAKKEELERLKKRLTGLT------PEKLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 556 KLKSEMEEKVYSLTKERDELMGKlrseeerscelscsvdlLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRELTLE 635
Cdd:PRK03918 398 KAKEEIEEEISKITARIGELKKE-----------------IKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAE 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 636 IERLKKRLQQLEVVEGDLMKTEDEYDqleqKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKgEAVSQEAELrhrFRMEEA 715
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELE----KVLKKESELIKLKELAEQLKELEEKLKKYNL-EELEKKAEE---YEKLKE 532
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1270111363 716 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGRE 768
Cdd:PRK03918 533 KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFE 585
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
153-777 |
4.19e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.87 E-value: 4.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 153 RLEEKQKETYRRM------LEQL--LLAEKchRRTVYELENEKHKHTDYMNKSDDFTNL--------LEQERERLKKLLE 216
Cdd:TIGR02168 169 KYKERRKETERKLertrenLDRLedILNEL--ERQLKSLERQAEKAERYKELKAELRELelallvlrLEELREELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 217 QEKAYQaRKEKENAKRLNKLRDELVKLKSFalMLVDERQMHIEQLGLQS--QKVQDLTQKLREEEEKL-------KAITY 287
Cdd:TIGR02168 247 ELKEAE-EELEELTAELQELEEKLEELRLE--VSELEEEIEELQKELYAlaNEISRLEQQKQILRERLanlerqlEELEA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 288 KSKEDRQKLLKLEVDFEHKASRFSQ----------EHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKaee 357
Cdd:TIGR02168 324 QLEELESKLDELAEELAELEEKLEElkeelesleaELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN--- 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 358 ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKD--EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL 435
Cdd:TIGR02168 401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 436 EKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE---LEVVKSRVKELECSESRLEK-VELSLKDDLTklksftvMLVDE 511
Cdd:TIGR02168 481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNqsgLSGILGVLSELISVDEGYEAaIEAALGGRLQ-------AVVVE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 512 RKNMMEKI----KQEE--------------RKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYsLTKERD 573
Cdd:TIGR02168 554 NLNAAKKAiaflKQNElgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLD 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 574 ELMGKLRSEEERSCELSCSVDLLK----------KRLDGIEEVEREINR-GRLCKGSEftcpedNKIRELTLEIERLKKR 642
Cdd:TIGR02168 633 NALELAKKLRPGYRIVTLDGDLVRpggvitggsaKTNSSILERRREIEElEEKIEELE------EKIAELEKALAELRKE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 643 LQQLEVVEGDLMKTEDEYDQ----LEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAvSQEAELRHRFRMEEAKSR 718
Cdd:TIGR02168 707 LEELEEELEQLRKELEELSRqisaLRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE-ERLEEAEEELAEAEAEIE 785
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1270111363 719 DLQAEVQALKEKI----HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 777
Cdd:TIGR02168 786 ELEAQIEQLKEELkalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
64-758 |
1.90e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 1.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 64 ESEKKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTE----KTKPEVLEAHYGSAEpEKVLRVLHRDAILAQEKSI 139
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEvselEEEIEELQKELYALA-NEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 140 GEDVYEKPISELDRLEEKQKETYR---RMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLE 216
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEelaELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 217 QEKAYQARKEkENAKRLNKLRDELVKLKSFALMLVD-----ERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKE 291
Cdd:TIGR02168 394 QIASLNNEIE-RLEARLERLEDRRERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 292 DRQKLLKLEVDFEHKASRFS-----QEHEEMNAKLANQESHNRQlrlKLVGLSQRIEELEETNKSLQKA-EEELQELRDK 365
Cdd:TIGR02168 473 AEQALDAAERELAQLQARLDslerlQENLEGFSEGVKALLKNQS---GLSGILGVLSELISVDEGYEAAiEAALGGRLQA 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 366 IAKGecGNSSLMAEVESLRK----RVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL------ 435
Cdd:TIGR02168 550 VVVE--NLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlv 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 436 -EKLEEAFSRSKSecTQLHLNL------------------EKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKD 496
Cdd:TIGR02168 628 vDDLDNALELAKK--LRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 497 DLTKLKSFTVMLVDErknmmekIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELM 576
Cdd:TIGR02168 706 ELEELEEELEQLRKE-------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 577 ---GKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEdNKIRELTLEIERLKkrlQQLEVVEGDL 653
Cdd:TIGR02168 779 eaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE-RRIAATERRLEDLE---EQIEELSEDI 854
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 654 MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAknkaiekgEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHE 733
Cdd:TIGR02168 855 ESLAAEIEELEELIEELESELEALLNERASLEEALA--------LLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
|
730 740
....*....|....*....|....*
gi 1270111363 734 LmnkEDQLSQLQVDYSVLQQRFMEE 758
Cdd:TIGR02168 927 L---ELRLEGLEVRIDNLQERLSEE 948
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
204-575 |
2.40e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 78.19 E-value: 2.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 204 LEQERERLKKLLEQEKAYQARKEkenakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLK 283
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELR-----RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK---ERLEELEEDLS 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 284 AITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--------KLANQESHNRQLRLKLVGLSQRIEELE-ETNKSLQK 354
Cdd:TIGR02169 748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEEVSRIEARLREIEqKLNRLTLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 355 ---AEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLqeeehhsKELRLEVEKLQKR 431
Cdd:TIGR02169 828 keyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE---EELEELEAALRDLESRL-------GDLKKERDELEAQ 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 432 MSELEKLEEafsrsksectQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDdltklksftvmlvde 511
Cdd:TIGR02169 898 LRELERKIE----------ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS--------------- 952
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111363 512 rknmMEKIKQEERKVDglnknfkVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL 575
Cdd:TIGR02169 953 ----LEDVQAELQRVE-------EEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
329-685 |
5.36e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 77.03 E-value: 5.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 329 RQLRLKLVGLSQRIEELEETNKSLQ----KAEEELQELRDKIAKGECGNSSLMAEVESLRKrvlEMEGKDEEITKTEAQC 404
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQselrRIENRLDELSQELSDASRKIGEIEKEIEQLEQ---EEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 405 RELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRsksectqlHLNLEKEKNLTkdllNELEVVKSRVKELECSE 484
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--------RLSHSRIPEIQ----AELSKLEEEVSRIEARL 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 485 SRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvtEKLIEESKKLLKLKSEMEEK 564
Cdd:TIGR02169 815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK-----------EELEEELEELEAALRDLESR 883
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 565 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLD----GIEEVEREINR-GRLCKGSEFTCPEDNKIRELTLEIERL 639
Cdd:TIGR02169 884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSelkaKLEALEEELSEiEDPKGEDEEIPEEELSLEDVQAELQRV 963
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1270111363 640 KKRLQQLEVVEgdlMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIK 685
Cdd:TIGR02169 964 EEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
167-834 |
7.28e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 7.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 167 EQLLLAEKCHRRTVYELEnEKHKHTDYMNKSDDFTNLLEQER-ERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKS 245
Cdd:PTZ00121 1095 EAFGKAEEAKKTETGKAE-EARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE 1173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 246 FALMLVDERQMHIEQLGLQSQKVQDL--TQKLREEEEKLKAITYKSKEDRQKLLKLEvdfehKASRFSQEHEEmnAKLAN 323
Cdd:PTZ00121 1174 DAKKAEAARKAEEVRKAEELRKAEDArkAEAARKAEEERKAEEARKAEDAKKAEAVK-----KAEEAKKDAEE--AKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 324 QESHNRQLRLKLVGLSQRIEELEETNKSLQKAE-EELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTE- 401
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEe 1326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 402 --AQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEK---EKNLTKDLLNELEVVKSR 476
Cdd:PTZ00121 1327 akKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkaeEKKKADEAKKKAEEDKKK 1406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 477 VKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIK---QEERKVDGLNKnfKVEQGKVMDVTEKLIEESKK 553
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKkkaEEAKKAEEAKK--KAEEAKKADEAKKKAEEAKK 1484
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 554 LLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK-----RLDGIEEVEREINRGRLCKGSEFTCPED-N 627
Cdd:PTZ00121 1485 ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeeakKADEAKKAEEKKKADELKKAEELKKAEEkK 1564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 628 KIRELTLEIERLKKRLQQLEVVEgdlmktEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELR 707
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAK------KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 708 HRFRMEEA-KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysvLQQRFMEEETKNKNMGREVLNLTKELELSKRYSRAL 786
Cdd:PTZ00121 1639 KKKEAEEKkKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 1270111363 787 RPSGNGRRMVDVpvasTGVQTEAVCGDAAEEETPAVFIRKSFQEENHI 834
Cdd:PTZ00121 1716 KKAEELKKAEEE----NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
33-717 |
7.92e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 76.72 E-value: 7.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 33 SEDAKKNKANRKGEDDVMASGTVK----RHLKPSGESEKKTKKPLELSKEDLIQLLSIMEGElQAREDVIHMLKTEKTKP 108
Cdd:PTZ00121 1172 AEDAKKAEAARKAEEVRKAEELRKaedaRKAEAARKAEEERKAEEARKAEDAKKAEAVKKAE-EAKKDAEEAKKAEEERN 1250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 109 EVLEAHYGSAEPEKVLRvlHRDAILAQEKSIGEDVyeKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTvyelENEKH 188
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFAR--RQAAIKAEEARKADEL--KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA----DEAKK 1322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 189 KHTDYMNKSDDFTNLLEQERER--LKKLLEQEKAYQARKEKENAKRlNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQ 266
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAaeAAKAEAEAAADEAEAAEEKAEA-AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 267 KVQDLTQKLRE-EEEKLKAITYKSKEDRQKL---LKLEVDFEHKASRFSQEHEEmnAKLANQESHNRQLRLKLVGLSQRI 342
Cdd:PTZ00121 1402 EDKKKADELKKaAAAKKKADEAKKKAEEKKKadeAKKKAEEAKKADEAKKKAEE--AKKAEEAKKKAEEAKKADEAKKKA 1479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 343 EELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQE----EEHHS 418
Cdd:PTZ00121 1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADElkkaEELKK 1559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 419 KELRLEVEKLQK----RMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSL 494
Cdd:PTZ00121 1560 AEEKKKAEEAKKaeedKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK 1639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 495 KDDLTKLKSFTVMLVDERKNmmeKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESkklLKLKSEMEEKVYSLTKERDE 574
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEEN---KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA---LKKEAEEAKKAEELKKKEAE 1713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 575 LMGK---LRSEEErscELSCSVDLLKKRLdgiEEVEREINRGRLCKGseftcpEDNKIRELTLEIERLKKRL-QQLEVVE 650
Cdd:PTZ00121 1714 EKKKaeeLKKAEE---ENKIKAEEAKKEA---EEDKKKAEEAKKDEE------EKKKIAHLKKEEEKKAEEIrKEKEAVI 1781
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111363 651 GDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKS 717
Cdd:PTZ00121 1782 EEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADA 1848
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
204-777 |
1.45e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 1.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 204 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 283
Cdd:COG1196 205 LERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 284 AITYKSKEDRQKLLKLEVDFEH---KASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRI----EELEETNKSLQKAE 356
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARleeRRRELEERLEELEEELAELEEELEELEEELEELEEELeeaeEELEEAEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 357 EELQELRDKIAKGEcgnsslmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELE 436
Cdd:COG1196 365 EALLEAEAELAEAE-------EELEELAEELLEAL---RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 437 KLEEAfsrsksectqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMM 516
Cdd:COG1196 435 EEEEE----------EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 517 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIE-----------------------ESKKLLKLKSEMEEKVYSLTKERD 573
Cdd:COG1196 505 GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEaaleaalaaalqnivveddevaaAAIEYLKAAKAGRATFLPLDKIRA 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 574 ELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRlckgSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDL 653
Cdd:COG1196 585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR----TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 654 MKTEdeydqleqkfRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHE 733
Cdd:COG1196 661 SLTG----------GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1270111363 734 LMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMG---REVLNLTKELE 777
Cdd:COG1196 731 EAEREELLEELLEEEELLEEEALEELPEPPDLEeleRELERLEREIE 777
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
251-603 |
1.48e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.87 E-value: 1.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 251 VDERQMHIEQLGLQSQKVQdltqKLREEEEKLKAITYKSKEDRQKLLKLEVDfEHKASRfsqehEEMNAKLANQESHNRQ 330
Cdd:TIGR02169 186 IERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLKEKE-ALERQK-----EAIERQLASLEEELEK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 331 LRLKLVGLSQRIEELEETNKSLQK-----AEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGK----DEEITKTE 401
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERlaklEAEIDKLL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 402 AQCRELKKKLQEEEHHSKELRLEVEKLQKRM----SELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRV 477
Cdd:TIGR02169 336 AEIEELEREIEEERKRRDKLTEEYAELKEELedlrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 478 KELECSESRLEKVELSLKDDLTKLKSftvmlvdERKNMMEKIKQEErkvdglnknfkveqGKVMDVTEKLIEESKKLLKL 557
Cdd:TIGR02169 416 QRLSEELADLNAAIAGIEAKINELEE-------EKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDL 474
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1270111363 558 KSE---MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGI 603
Cdd:TIGR02169 475 KEEydrVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
204-696 |
1.85e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.36 E-value: 1.85e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 204 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 283
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 284 AITYK------SKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEE 357
Cdd:COG1196 401 QLEELeeaeeaLLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 358 ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDE--EITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL 435
Cdd:COG1196 481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 436 EKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVkeLECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNM 515
Cdd:COG1196 561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD--LVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 516 MEKIKQEERKV----DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSC 591
Cdd:COG1196 639 AVTLAGRLREVtlegEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 592 SVDLLKKRLDGIEEVEREINRGRLCKGSE------FTCPEDNKIRELTLEIERLKKRLQQLEVVEgdlMKTEDEYDQLEQ 665
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELLEEEELleeealEELPEPPDLEELERELERLEREIEALGPVN---LLAIEEYEELEE 795
|
490 500 510
....*....|....*....|....*....|..
gi 1270111363 666 KFrteqdkaNFLSQQLEEIKHQMAK-NKAIEK 696
Cdd:COG1196 796 RY-------DFLSEQREDLEEARETlEEAIEE 820
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
30-565 |
2.24e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.18 E-value: 2.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 30 KGPSEDAKKNKANRKGEDDVMASGTVKRHLKPSGESEKKTKKPLELSKEDLIQllsiMEGELQAREDVIHMLKTEKTKPE 109
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK----KKAEEAKKADEAKKKAEEAKKAE 1460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 110 VLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETyrrmlEQLLLAEKchRRTVYELEN-EKH 188
Cdd:PTZ00121 1461 EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA-----DEAKKAEE--AKKADEAKKaEEA 1533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 189 KHTDYMNKSDDFTNLLE-QERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKlksfalmlVDERQMHIEQLGLQSQK 267
Cdd:PTZ00121 1534 KKADEAKKAEEKKKADElKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK--------AEEARIEEVMKLYEEEK 1605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 268 VQDLTQKLREEEEKLKAITYKSKEDRQK----LLKLEVDFEHKASRFSQEHEEMNAKLAnqeshnrQLRLKLVGLSQRIE 343
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKkveqLKKKEAEEKKKAEELKKAEEENKIKAA-------EEAKKAEEDKKKAE 1678
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 344 ELEETNKSLQKAEEELQELRDKIAKgecgnsslmaeVESLRKRVLEMEGKDEEITKTE----AQCRELKKKLQEEEHHSK 419
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKK-----------AEELKKKEAEEKKKAEELKKAEeenkIKAEEAKKEAEEDKKKAE 1747
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 420 ELRLEVE---KLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNL------TKDLLNELEVVKSRVKELECSESRLEKV 490
Cdd:PTZ00121 1748 EAKKDEEekkKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRmevdkkIKDIFDNFANIIEGGKEGNLVINDSKEM 1827
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 491 ELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKlIEESKKLLKL-KSEMEEKV 565
Cdd:PTZ00121 1828 EDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEE-IEEADEIEKIdKDDIEREI 1902
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
213-777 |
5.43e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.52 E-value: 5.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 213 KLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfaLMLVDERQMH-----IEQLGLQSQKVQDLTQKLREEEEKLKAITY 287
Cdd:TIGR04523 78 KILEQQIKDLNDKLKKNKDKINKLNSDLSKINS--EIKNDKEQKNkleveLNKLEKQKKENKKNIDKFLTEIKKKEKELE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 288 KSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVglsqRIEELEETNKSLQKAEEELQELrdkia 367
Cdd:TIGR04523 156 KLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLESQISELKKQ----- 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 368 kgecgNSSLMAEVESLRKrvlEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLeeaFSRSKS 447
Cdd:TIGR04523 227 -----NNQLKDNIEKKQQ---EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQ---LNQLKS 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 448 ECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 527
Cdd:TIGR04523 296 EI--SDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 528 GLNKNfkveqgkvmdvTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVE 607
Cdd:TIGR04523 374 KLKKE-----------NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET---IIKNN 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 608 REInrgrlckgSEFTcpedNKIRELTLEIERLKKRL----QQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 683
Cdd:TIGR04523 440 SEI--------KDLT----NQDSVKELIIKNLDNTResleTQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 684 IKHQMaKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIH------ELMNKEDQLSQLQVDYSVLQQRFME 757
Cdd:TIGR04523 508 LEEKV-KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkenlekEIDEKNKEIEELKQTQKSLKKKQEE 586
|
570 580
....*....|....*....|
gi 1270111363 758 EETKNKNMGREVLNLTKELE 777
Cdd:TIGR04523 587 KQELIDQKEKEKKDLIKEIE 606
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
202-738 |
1.11e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 72.36 E-value: 1.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 202 NLLEQERERLKKLLEQEKAYQA------RKEKENAKRLNKLRDELVKLKsfaLMLVDERQMHIEQLGLQSQKVQDLTQKL 275
Cdd:TIGR04523 120 NKLEVELNKLEKQKKENKKNIDkflteiKKKEKELEKLNNKYNDLKKQK---EELENELNLLEKEKLNIQKNIDKIKNKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 276 REEEEKLKAItyKSKEDRQKLLKLEV-DFEHKASRF-------SQEHEEMNAKLANQESHNRQLRLKLVG----LSQRIE 343
Cdd:TIGR04523 197 LKLELLLSNL--KKKIQKNKSLESQIsELKKQNNQLkdniekkQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQK 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 344 ELEETNKSLQKAEEELQELRDKIA-----KGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHS 418
Cdd:TIGR04523 275 ELEQNNKKIKELEKQLNQLKSEISdlnnqKEQDWNKELKSELKNQEKKLEEIQ---NQISQNNKIISQLNEQISQLKKEL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 419 KELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNltkDLLNELEVVKSRVKELECSESRLEKVELSLKDDL 498
Cdd:TIGR04523 352 TNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIN---DLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 499 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvyslTKERDELMGK 578
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK----EKELKKLNEE 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 579 LRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRE-LTLEIERLKKRLQQLEVVEGDLMKTE 657
Cdd:TIGR04523 505 KKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEnLEKEIDEKNKEIEELKQTQKSLKKKQ 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 658 DEYDQLEQKFrtEQDKANFLSQQLEEIKHQMAKNKAIEKGEAvsQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNK 737
Cdd:TIGR04523 585 EEKQELIDQK--EKEKKDLIKEIEEKEKKISSLEKELEKAKK--ENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
|
.
gi 1270111363 738 E 738
Cdd:TIGR04523 661 W 661
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
338-728 |
1.52e-12 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 72.11 E-value: 1.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 338 LSQRIEELEETNKSLQKAEEELQELRDKIAKgecgnssLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHH 417
Cdd:COG4717 76 LEEELKEAEEKEEEYAELQEELEELEEELEE-------LEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPER 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 418 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQL--HLNLEKEKNLtKDLLNELEVVKSRVKELecsESRLEKVELSLK 495
Cdd:COG4717 148 LEELEERLEELRELEEELEELEAELAELQEELEELleQLSLATEEEL-QDLAEELEELQQRLAEL---EEELEEAQEELE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 496 DDLTKLKSFTVMLVDERKNmmEKIKQEERK---------VDGLNKNFKVEQGKVMDV------------------TEKLI 548
Cdd:COG4717 224 ELEEELEQLENELEAAALE--ERLKEARLLlliaaallaLLGLGGSLLSLILTIAGVlflvlgllallflllareKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 549 EESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREI-------NRGRLCKGSEF 621
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqleeleqEIAALLAEAGV 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 622 TCPED--------NKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEyDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKA 693
Cdd:COG4717 382 EDEEElraaleqaEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELEA 460
|
410 420 430
....*....|....*....|....*....|....*.
gi 1270111363 694 -IEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALK 728
Cdd:COG4717 461 eLEQLEEDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
152-799 |
3.02e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 71.30 E-value: 3.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 152 DRLEEKQKETYRRMleQLLLAEKCHR--RTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 229
Cdd:pfam15921 245 DQLEALKSESQNKI--ELLLQQHQDRieQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 230 AKRLNKLRDELVKLKSfalMLVDERQMHIEQLGLQSQkvqDLTQKLREEEEklkaITYKSKEDRQKLLKLEVDFEHKASR 309
Cdd:pfam15921 323 ESTVSQLRSELREAKR---MYEDKIEELEKQLVLANS---ELTEARTERDQ----FSQESGNLDDQLQKLLADLHKREKE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 310 FSQEHEEmNAKLANQESHNR----QLRLKLVGLSQRIEELEETNKSLQ-----KAEEELQELRDKIAKGEcGNSSLMAEV 380
Cdd:pfam15921 393 LSLEKEQ-NKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKsecqgQMERQMAAIQGKNESLE-KVSSLTAQL 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 381 ES----LRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR----MSELEKL---EEAFSRSKSEC 449
Cdd:pfam15921 471 EStkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlkLQELQHLkneGDHLRNVQTEC 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 450 TQLHLNLEKEKNLTKDLLNELEVVKSRVKE-------LECSESRLEKvelSLKDDLTKLKSFTVMlvDERKNmmEKIKQE 522
Cdd:pfam15921 551 EALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQLEK---EINDRRLELQEFKIL--KDKKD--AKIREL 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 523 ERKVDGLNKnfkveqgkvmdvteklieESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRL-D 601
Cdd:pfam15921 624 EARVSDLEL------------------EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFrN 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 602 GIEEVEREINRGRLckgseftcpednKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQL 681
Cdd:pfam15921 686 KSEEMETTTNKLKM------------QLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFL 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 682 EEIKHQMAKNKAIEKGE--AVSQEAELRHRFRMEEAKSRD-LQAEVQALKEKIhelMNKEDQLSQLQVDYSVLQQRFMEE 758
Cdd:pfam15921 754 EEAMTNANKEKHFLKEEknKLSQELSTVATEKNKMAGELEvLRSQERRLKEKV---ANMEVALDKASLQFAECQDIIQRQ 830
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 1270111363 759 ETKNKNMGREVLNLTKELE------LSKRYSRALRPSGNGRRMVDVP 799
Cdd:pfam15921 831 EQESVRLKLQHTLDVKELQgpgytsNSSMKPRLLQPASFTRTHSNVP 877
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
128-787 |
7.37e-12 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 69.75 E-value: 7.37e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 128 HRDAILAQEKSIGEDVYEKPISELdRLEEKQKETYRRMLEQL-------LLAEKCHRR----TVYELENEKHKHTdYMNK 196
Cdd:pfam05483 111 NRKIIEAQRKAIQELQFENEKVSL-KLEEEIQENKDLIKENNatrhlcnLLKETCARSaektKKYEYEREETRQV-YMDL 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 197 SDDFTNLLeQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfalmlVDERQMHIEQLGLQS----QKVQDLT 272
Cdd:pfam05483 189 NNNIEKMI-LAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE-------INDKEKQVSLLLIQItekeNKMKDLT 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 273 QKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSL 352
Cdd:pfam05483 261 FLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEEL 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 353 QKAEEELQELRDKIAKGECGNSSLM-AEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL---EVEKL 428
Cdd:pfam05483 341 NKAKAAHSFVVTEFEATTCSLEELLrTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKilaEDEKL 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 429 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEknlTKDLLNELEVVKS-------RVKEL--ECSESRLEKVELSLKDDLT 499
Cdd:pfam05483 421 LDEKKQFEKIAEELKGKEQELIFLLQAREKE---IHDLEIQLTAIKTseehylkEVEDLktELEKEKLKNIELTAHCDKL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 500 KLKSFTvmLVDERKNMMEKIKQEERKVDglnkNFKVEQGKVMDVTEKLIEeskKLLKLKSEMEEKVYSLTKERDELMGKL 579
Cdd:pfam05483 498 LLENKE--LTQEASDMTLELKKHQEDII----NCKKQEERMLKQIENLEE---KEMNLRDELESVREEFIQKGDEVKCKL 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 580 RSEEERSCELSCSVDLLKKRLDGIEEVereinrgrlCKGSEFTCPEDNK-IRELTLEIERLKKR----LQQLEVVEGDLM 654
Cdd:pfam05483 569 DKSEENARSIEYEVLKKEKQMKILENK---------CNNLKKQIENKNKnIEELHQENKALKKKgsaeNKQLNAYEIKVN 639
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 655 KTEDEYDQLEQKF----RTEQDKANFLSQQLEEIKHQMAKNKAIEKgEAVSQEAELRHRFRMEeaksrdlQAEVQALKEK 730
Cdd:pfam05483 640 KLELELASAKQKFeeiiDNYQKEIEDKKISEEKLLEEVEKAKAIAD-EAVKLQKEIDKRCQHK-------IAEMVALMEK 711
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 731 IHELMNK--EDQLSQLQVDYSVLQQRFMEE---ETKNKNMGREVLNLTKELELSKRYSRALR 787
Cdd:pfam05483 712 HKHQYDKiiEERDSELGLYKNKEQEQSSAKaalEIELSNIKAELLSLKKQLEIEKEEKEKLK 773
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
194-612 |
2.80e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.16 E-value: 2.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 194 MNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKsfalmlvderqmhieqlglqsqkvQDLTQ 273
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE------------------------EELEQ 716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 274 KLREEEEKLKAITyKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETnksLQ 353
Cdd:TIGR02168 717 LRKELEELSRQIS-ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ---IE 792
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 354 KAEEELQELRDKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEehhSKELRLEVEKLQKRMS 433
Cdd:TIGR02168 793 QLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ---IEELSEDIESLAAEIE 862
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 434 ELEKLEEAfsrsksectqlhlnLEKEknlTKDLLNELEVVKSRVKELecsESRLEKVELSLKDDLTKLKSftvmLVDERK 513
Cdd:TIGR02168 863 ELEELIEE--------------LESE---LEALLNERASLEEALALL---RSELEELSEELRELESKRSE----LRRELE 918
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 514 NMMEKIKQEERKVDGLNKNFKVEQGKVM----DVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL-------MGKLRSE 582
Cdd:TIGR02168 919 ELREKLAQLELRLEGLEVRIDNLQERLSeeysLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEEL 998
|
410 420 430
....*....|....*....|....*....|
gi 1270111363 583 EERSCELSCSVDLLKKRLDGIEEVEREINR 612
Cdd:TIGR02168 999 KERYDFLTAQKEDLTEAKETLEEAIEEIDR 1028
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
203-760 |
4.91e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 67.37 E-value: 4.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 203 LLEQERERLKKLLEQekaYQARKEKENAKRLNKLRDELVKLKS------------------FALMLVD--ERQMHIEQLG 262
Cdd:PRK02224 181 VLSDQRGSLDQLKAQ---IEEKEEKDLHERLNGLESELAELDEeieryeeqreqaretrdeADEVLEEheERREELETLE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 263 lqsQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEH----------KASRFSQEHEEMNAKLANQESHNRQLR 332
Cdd:PRK02224 258 ---AEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDllaeaglddaDAEAVEARREELEDRDEELRDRLEECR 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 333 LKLV-------GLSQRIEELEETNKSLQKA----EEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTE 401
Cdd:PRK02224 335 VAAQahneeaeSLREDADDLEERAEELREEaaelESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 402 AQCRELKKKLQEEEhhsKELRLEVEKLQKRMSELEKLEEAfsrSK-SECTQlhlNLEKEknltkdllnelevvkSRVKEL 480
Cdd:PRK02224 415 EELREERDELRERE---AELEATLRTARERVEEAEALLEA---GKcPECGQ---PVEGS---------------PHVETI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 481 ECSESRLEKVELSLKDDLTKLKSftvmlVDERKNMMEKIKQEERKVDGLNKNfkveqgkvMDVTEKLIEESKKLLKlksE 560
Cdd:PRK02224 471 EEDRERVEELEAELEDLEEEVEE-----VEERLERAEDLVEAEDRIERLEER--------REDLEELIAERRETIE---E 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 561 MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREIN--RGRLCKGSEftcpEDNKIRELTLEIER 638
Cdd:PRK02224 535 KRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKerIESLERIRT----LLAAIADAEDEIER 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 639 LKKRLQQLEVVEgdlmktedeyDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKaieKGEAVSQEAELRHRFRMEEAKSR 718
Cdd:PRK02224 611 LREKREALAELN----------DERRERLAEKRERKRELEAEFDEARIEEARED---KERAEEYLEQVEEKLDELREERD 677
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1270111363 719 DLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEET 760
Cdd:PRK02224 678 DLQAEIGAVENELEELEELRERREALENRVEALEALYDEAEE 719
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
405-781 |
6.52e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.02 E-value: 6.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 405 RELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLtkdLLNELEVVKSRVKELECSE 484
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 485 SRLEKVELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLnknfkvEQGKVMDVTEKLIEESKKLLKLKSEMEEK 564
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEA-------RIEELEEDLHKLEEALNDL------EARLSHSRIPEIQAELSKLEEEVSRIEAR 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 565 VYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRldgIEEVEREINRGRLckgseftcpednKIRELTLEIERLKKRLQ 644
Cdd:TIGR02169 814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ---IKSIEKEIENLNG------------KKEELEEELEELEAALR 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 645 QLEVVEGDLMKtedEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAiEKGEAVSQEAELRHRFRM------EEAKSR 718
Cdd:TIGR02169 879 DLESRLGDLKK---ERDELEAQLRELERKIEELEAQIEKKRKRLSELKA-KLEALEEELSEIEDPKGEdeeipeEELSLE 954
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111363 719 DLQAEVQALKEKIHEL----MNKEDQLSQLQVDYSVLQQRFMEEETKNKnmgrEVLNLTKELELSKR 781
Cdd:TIGR02169 955 DVQAELQRVEEEIRALepvnMLAIQEYEEVLKRLDELKEKRAKLEEERK----AILERIEEYEKKKR 1017
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
395-741 |
7.94e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 7.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 395 EEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVvk 474
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA-- 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 475 srvkELECSESRLEKVELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL 554
Cdd:TIGR02168 762 ----EIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 555 LKLKSEMEEKVYSLTKERDElmgklrseeerscelscsvdllkkrldgIEEVEREINRGRLckgseftcpednKIRELTL 634
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSED----------------------------IESLAAEIEELEE------------LIEELES 873
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 635 EIERLKKRLQQLEVvegDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAiEKGEAVSQEAELRHRFRME- 713
Cdd:TIGR02168 874 ELEALLNERASLEE---ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-RLEGLEVRIDNLQERLSEEy 949
|
330 340 350
....*....|....*....|....*....|....*
gi 1270111363 714 -------EAKSRDLQAEVQALKEKIHELMNKEDQL 741
Cdd:TIGR02168 950 sltleeaEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
181-780 |
8.94e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 66.53 E-value: 8.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 181 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKlleqekayQARKEKENAKRLNKLRDELVKLKsfalmLVDERQMHIEQ 260
Cdd:pfam02463 172 KEALKKLIEETENLAELIIDLEELKLQELKLKE--------QAKKALEYYQLKEKLELEEEYLL-----YLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 261 LglqsQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQ 340
Cdd:pfam02463 239 I----DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 341 RIEELEETNKSLQKAEEELQELRDKIAKgecgnsslmaEVESLRKRVLEMEgkdeeiTKTEAQCRELKKKLQEEEHHSKE 420
Cdd:pfam02463 315 KLKESEKEKKKAEKELKKEKEEIEELEK----------ELKELEIKREAEE------EEEEELEKLQEKLEQLEEELLAK 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 421 LRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLN-ELEVVKSRVKELECSESRLEKVELSLKDDLT 499
Cdd:pfam02463 379 KKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKeELEILEEEEESIELKQGKLTEEKEELEKQEL 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 500 KLKSFTVMLVDERKNMMEKIKQEERkvdgLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKL 579
Cdd:pfam02463 459 KLLKDELELKKSEDLLKETQLVKLQ----EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDL 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 580 RSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLckgsEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDE 659
Cdd:pfam02463 535 GVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL----TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 660 YDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAEL---RHRFRMEEAKSRDLQAEVQALKEKIHELMN 736
Cdd:pfam02463 611 ATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGlaeKSEVKASLSELTKELLEIQELQEKAESELA 690
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1270111363 737 KEDQLSQLQvDYSVLQQRFMEEETKNKNMGREVLNLTKELELSK 780
Cdd:pfam02463 691 KEEILRRQL-EIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
153-780 |
1.24e-10 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 66.22 E-value: 1.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 153 RLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERL-----KKLLEQEKAYQARKEK 227
Cdd:TIGR00606 287 ELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELlveqgRLQLQADRHQEHIRAR 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 228 ENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKA 307
Cdd:TIGR00606 367 DSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKK 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 308 SRFSQEHEEMNAKLANQEshnrqlrlKLVGLSQRIEELEEtnkSLQKAEEELQELRDKiakgecgnsslmAEVESLRKRV 387
Cdd:TIGR00606 447 EILEKKQEELKFVIKELQ--------QLEGSSDRILELDQ---ELRKAERELSKAEKN------------SLTETLKKEV 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 388 LEMEGKDEEITKTEaqcRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECT----------QLHLNLE 457
Cdd:TIGR00606 504 KSLQNEKADLDRKL---RKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTsllgyfpnkkQLEDWLH 580
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 458 KEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKL--KSFTVMLVDERKNMMEKIKQEERKV--------- 526
Cdd:TIGR00606 581 SKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYedKLFDVCGSQDEESDLERLKEEIEKSskqramlag 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 527 -----DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELscsVDLLKKRLD 601
Cdd:TIGR00606 661 atavySQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEM---LGLAPGRQS 737
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 602 GIEEVEREINRGRlckgseftcpedNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQL 681
Cdd:TIGR00606 738 IIDLKEKEIPELR------------NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVE 805
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 682 EEIKHQMAKNKAIEKGEAVSQ----EAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 757
Cdd:TIGR00606 806 RKIAQQAAKLQGSDLDRTVQQvnqeKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ 885
|
650 660
....*....|....*....|...
gi 1270111363 758 EETKNKNMGREVLNLTKELELSK 780
Cdd:TIGR00606 886 FEEQLVELSTEVQSLIREIKDAK 908
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
62-452 |
2.23e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.46 E-value: 2.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 62 SGESEKKTKKPLELSKE--DLIQLLSIMEGELQAREDVIHMLKTEKTkpevleahygsaEPEKVLRVLHRDAILAQEKSI 139
Cdd:TIGR02168 662 TGGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELE------------ELEEELEQLRKELEELSRQIS 729
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 140 GEDvyekpiSELDRLEEKQkETYRRMLEQLllaekchRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQek 219
Cdd:TIGR02168 730 ALR------KDLARLEAEV-EQLEERIAQL-------SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ-- 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 220 ayQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEklkaitykskedrqKLLKL 299
Cdd:TIGR02168 794 --LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE--------------DIESL 857
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 300 EVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAE 379
Cdd:TIGR02168 858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 380 VESLRKRVLE------------MEGKDEEITKTEAQCRELKKKLQE---------EEHHSKELRLEVEKLQKR--MSELE 436
Cdd:TIGR02168 938 IDNLQERLSEeysltleeaealENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDFLTAQKEdlTEAKE 1017
|
410
....*....|....*.
gi 1270111363 437 KLEEAFSRSKSECTQL 452
Cdd:TIGR02168 1018 TLEEAIEEIDREARER 1033
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
121-748 |
5.02e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 64.17 E-value: 5.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 121 EKVLRVLHRDAILAQEKSIGEDVY----EKP--ISELDRLEEkQKETYRRMLEQLLLAEKCHRRtvyeLENEKHKHTDYM 194
Cdd:COG4913 191 EKALRLLHKTQSFKPIGDLDDFVReymlEEPdtFEAADALVE-HFDDLERAHEALEDAREQIEL----LEPIRELAERYA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 195 NKSDDFtNLLEQERERLKKLLEQEKAYQARKEKENAKR-LNKLRDELVKLKS-FALMLVDERQMHIEQLGLQSQKVQDLT 272
Cdd:COG4913 266 AARERL-AELEYLRAALRLWFAQRRLELLEAELEELRAeLARLEAELERLEArLDALREELDELEAQIRGNGGDRLEQLE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 273 QKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRlklvglsqriEELEETNKSL 352
Cdd:COG4913 345 REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE----------EALAEAEAAL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 353 QKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLemegkdEEITKTEAQCR---ELKKKLQEEEH---------HSKE 420
Cdd:COG4913 415 RDLRRELRELEAEIASLERRKSNIPARLLALRDALA------EALGLDEAELPfvgELIEVRPEEERwrgaiervlGGFA 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 421 LRLEVEklqkrmselEKLEEAFSRS-KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE---KVELSlkd 496
Cdd:COG4913 489 LTLLVP---------PEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRawlEAELG--- 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 497 dltklKSFTVMLVDERknmmEKIKQEERKV--DGL----------NKNFKVEQGKVM--DVTEKLIEESKKLLKLKSEME 562
Cdd:COG4913 557 -----RRFDYVCVDSP----EELRRHPRAItrAGQvkgngtrhekDDRRRIRSRYVLgfDNRAKLAALEAELAELEEELA 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 563 EkvysLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDgIEEVEREINRGRlckgseftcpedNKIRELTL---EIERL 639
Cdd:COG4913 628 E----AEERLEALEAELDALQERREALQRLAEYSWDEID-VASAEREIAELE------------AELERLDAssdDLAAL 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 640 KKRLQQLEVVEGDLmktEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAknkAIEKGEAVSQEAELRHRF------RME 713
Cdd:COG4913 691 EEQLEELEAELEEL---EEELDELKGEIGRLEKELEQAEEELDELQDRLE---AAEDLARLELRALLEERFaaalgdAVE 764
|
650 660 670
....*....|....*....|....*....|....*
gi 1270111363 714 EAKSRDLQAEVQALKEKIHelmNKEDQLSQLQVDY 748
Cdd:COG4913 765 RELRENLEERIDALRARLN---RAEEELERAMRAF 796
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
182-777 |
1.08e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.89 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 182 ELENEKHKHTDYMNKSDDFTNLLEQERerlKKLLEQEKAYQARKEKENAKRlNKLRDELV----KLKSFA---LMLVDER 254
Cdd:pfam01576 72 ELEEILHELESRLEEEEERSQQLQNEK---KKMQQHIQDLEEQLDEEEAAR-QKLQLEKVtteaKIKKLEediLLLEDQN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 255 QMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLK 334
Cdd:pfam01576 148 SKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLK-KEEKGRQELEKAKRKL---EGESTDLQEQ 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 335 LVGLSQRIEELEetnKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLE----MEGKDEEITKTEAQCRELKKK 410
Cdd:pfam01576 224 IAELQAQIAELR---AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISElqedLESERAARNKAEKQRRDLGEE 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 411 LQ----EEEHHSKELRLEVEKLQKRMSELEKLEEAF-SRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSES 485
Cdd:pfam01576 301 LEalktELEDTLDTTAAQQELRSKREQEVTELKKALeEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 486 RLEKVELSLKDDLTKLKSftvmlvderknmmekikqeeRKVDGLNKNFKVEqGKVMDVTEKLIEESKKllklKSEMEEKV 565
Cdd:pfam01576 381 ALESENAELQAELRTLQQ--------------------AKQDSEHKRKKLE-GQLQELQARLSESERQ----RAELAEKL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 566 YSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPED--NKIRELTLEIERLKKRL 643
Cdd:pfam01576 436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDerNSLQEQLEEEEEAKRNV 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 644 Q-QLEVVEGDLM----KTEDE---YDQLEQKFRTEQDKANFLSQQLEEikhqmaKNKAIEKGEavsqeaelRHRFRMEEa 715
Cdd:pfam01576 516 ErQLSTLQAQLSdmkkKLEEDagtLEALEEGKKRLQRELEALTQQLEE------KAAAYDKLE--------KTKNRLQQ- 580
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 716 KSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGRE----VLNLTKELE 777
Cdd:pfam01576 581 ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREketrALSLARALE 646
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
237-777 |
2.69e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 61.30 E-value: 2.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 237 RDELVKLKSFALMLVDE-RQMHIEQ---LGLQSQKVQDLTQKLREEEEKLKAItykskedrQKLLKLEVDFEHKASRFSQ 312
Cdd:pfam05557 1 RAELIESKARLSQLQNEkKQMELEHkraRIELEKKASALKRQLDRESDRNQEL--------QKRIRLLEKREAEAEEALR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 313 EHEEMN-AKLANQESHNRQLRLKlvglSQRIEELEETNKSLQKaeeELQELRDKIAKGECGNSSLMAEVESLRKR----- 386
Cdd:pfam05557 73 EQAELNrLKKKYLEALNKKLNEK----ESQLADAREVISCLKN---ELSELRRQIQRAELELQSTNSELEELQERldllk 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 387 ---------VLEMEGKDEEITKTEAQCRELKKKLQEEEHHS---KELRLEVEKLQKRMSELEKLEE--AFSRSKSECTQL 452
Cdd:pfam05557 146 akaseaeqlRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSeivKNSKSELARIPELEKELERLREhnKHLNENIENKLL 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 453 hlnLEKEKNLTKDLLNELEVVKSRVKELECSESRLE-------KVELSLKDDLTK---LKSFTVMLVDERKNMMEKIKQE 522
Cdd:pfam05557 226 ---LKEEVEDLKRKLEREEKYREEAATLELEKEKLEqelqswvKLAQDTGLNLRSpedLSRRIEQLQQREIVLKEENSSL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 523 ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS---EMEEKVYSLTKERDELMGKLRS------EEERSCELSCSV 593
Cdd:pfam05557 303 TSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKAlvrRLQRRVLLLTKERDGYRAILESydkeltMSNYSPQLLERI 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 594 DLLKKRLDGIEEVEREInRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVvegdlMKTEDEYDQLEQKFRTEQDK 673
Cdd:pfam05557 383 EEAEDMTQKMQAHNEEM-EAQLSVAEEELGGYKQQAQTLERELQALRQQESLADP-----SYSKEEVDSLRRKLETLELE 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 674 ANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAeLRHR-------FRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQv 746
Cdd:pfam05557 457 RQRLREQKNELEMELERRCLQGDYDPKKTKV-LHLSmnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLP- 534
|
570 580 590
....*....|....*....|....*....|.
gi 1270111363 747 dysvlqqrfmeeETKNKNMGREVLNLTKELE 777
Cdd:pfam05557 535 ------------ETTSTMNFKEVLDLRKELE 553
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
67-522 |
6.14e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.46 E-value: 6.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 67 KKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPekvlRVLHRDAILAQEKSIGEDVYEK 146
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEE----RHELYEEAKAKKEELERLKKRL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 147 PISELDRLEEKQKETYRRMLEqLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTN--------LLEQERERLKKLLEQE 218
Cdd:PRK03918 382 TGLTPEKLEKELEELEKAKEE-IEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpvcgreLTEEHRKELLEEYTAE 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 219 KAYQARKEKENAKRLNKLRDELVKLKSFalmLVDERQMhieqlglqsQKVQDLTQKLREEEEKLKAITYKskedrqkllk 298
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKV---LKKESEL---------IKLKELAEQLKELEEKLKKYNLE---------- 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 299 levdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIakGECGNSSL-- 376
Cdd:PRK03918 519 -------ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL--EELGFESVee 589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 377 ----MAEVESLRKRVL-------EMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMS--ELEKLEEAFS 443
Cdd:PRK03918 590 leerLKELEPFYNEYLelkdaekELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSeeEYEELREEYL 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 444 RSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDD---LTKLKSFTVMLVDERKNMMEKIK 520
Cdd:PRK03918 670 ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVeelREKVKKYKALLKERALSKVGEIA 749
|
..
gi 1270111363 521 QE 522
Cdd:PRK03918 750 SE 751
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
189-586 |
8.04e-09 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 60.48 E-value: 8.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 189 KHTDYMNKSDDFTNL-----LEQERERLKKLLE-----QEKAYQARKEKENAKRLNKLRDELVKLKsFALMLVDERQMHI 258
Cdd:COG5022 785 RLVDYELKWRLFIKLqpllsLLGSRKEYRSYLAciiklQKTIKREKKLRETEEVEFSLKAEVLIQK-FGRSLKAKKRFSL 863
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 259 EQ---LGLQSQ-KVQDLTQKLREEEEKLKAITY---KSKEDRQKLLKLEVDFEhkaSRFSQEHEEMNAKLANQESHNRQL 331
Cdd:COG5022 864 LKketIYLQSAqRVELAERQLQELKIDVKSISSlklVNLELESEIIELKKSLS---SDLIENLEFKTELIARLKKLLNNI 940
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 332 RLKlvglSQRIEELEEtNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTeaqcRELKKKL 411
Cdd:COG5022 941 DLE----EGPSIEYVK-LPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAEL----SKQYGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 412 QEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNeLEVVKSRVKELECSESRLEKVE 491
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKA-LKLRRENSLLDDKQLYQLESTE 1090
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 492 lslkddlTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvteKLIEESKKLLKLKS---EMEEKVYSL 568
Cdd:COG5022 1091 -------NLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKL------------NLLQEISKFLSQLVntlEPVFQKLSV 1151
|
410
....*....|....*...
gi 1270111363 569 TKERDELMGKLRSEEERS 586
Cdd:COG5022 1152 LQLELDGLFWEANLEALP 1169
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
56-588 |
9.83e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.99 E-value: 9.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 56 KRHLKPSGESEKKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQ 135
Cdd:pfam02463 470 SEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 136 EKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE-------KHKHTDYMNKSDDFTNLLEQER 208
Cdd:pfam02463 550 IVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDpilnlaqLDKATLEADEDDKRAKVVEGIL 629
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 209 ERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYK 288
Cdd:pfam02463 630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 289 SKEDRQKLLKLEVdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNK--SLQKAEEELQELRDKI 366
Cdd:pfam02463 710 EELKKLKLEAEEL----LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSelSLKEKELAEEREKTEK 785
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 367 AKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSK 446
Cdd:pfam02463 786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITK 865
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 447 SECTQlHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKV--------------ELSLKDDLTKLKSFTVMLVDER 512
Cdd:pfam02463 866 EELLQ-ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlnlleekeneieerIKEEAEILLKYEEEPEELLLEE 944
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 513 KNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCE 588
Cdd:pfam02463 945 ADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
343-564 |
1.66e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 1.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 343 EELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEHHSKELR 422
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 423 LEVEKLQKRMSELekLEEAFSRSKSECTQLHLNLEKEKNLTKDL--LNEL-EVVKSRVKELECSESRLEKVELSLKDDLT 499
Cdd:COG4942 97 AELEAQKEELAEL--LRALYRLGRQPPLALLLSPEDFLDAVRRLqyLKYLaPARREQAEELRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111363 500 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVmdvtEKLIEESKKLLKLKSEMEEK 564
Cdd:COG4942 175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL----AELQQEAEELEALIARLEAE 235
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
149-669 |
2.90e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 58.13 E-value: 2.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 149 SELDRLEEkQKETYRRMLEQLLLAEKCHRRTVYELENekhkhtdymnksddftnlLEQERERLkklleQEKAYQARKEKE 228
Cdd:PRK02224 220 EEIERYEE-QREQARETRDEADEVLEEHEERREELET------------------LEAEIEDL-----RETIAETERERE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 229 NAK-RLNKLRDELVKLKSFALMLVDERQM---HIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFE 304
Cdd:PRK02224 276 ELAeEVRDLRERLEELEEERDDLLAEAGLddaDAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 305 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEE----TNKSLQKAEEELQELRDKIAKGECGNSSLMAEV 380
Cdd:PRK02224 356 ERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdAPVDLGNAEDFLEELREERDELREREAELEATL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 381 ESLRKRVLEME-----GK---------DEEITKTEAQCRELKKKLQEEEhhsKELRLEVEKLQKRMSELEKLEEAFSRsk 446
Cdd:PRK02224 436 RTARERVEEAEalleaGKcpecgqpveGSPHVETIEEDRERVEELEAEL---EDLEEEVEEVEERLERAEDLVEAEDR-- 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 447 sectqlhlnLEKEKNLTKDLLNELEVVKSRV--KELECSESRLEKVELSLKDDLTKlksftvmlvDERKNMMEKIKQEER 524
Cdd:PRK02224 511 ---------IERLEERREDLEELIAERRETIeeKRERAEELRERAAELEAEAEEKR---------EAAAEAEEEAEEARE 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 525 KVDGLNKnfkvEQGKVMDVTEKLiEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDG-- 602
Cdd:PRK02224 573 EVAELNS----KLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEar 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 603 IEEVereinRGRLCKGSEFTCPEDNKIRELTL-----------------EIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ 665
Cdd:PRK02224 648 IEEA-----REDKERAEEYLEQVEEKLDELREerddlqaeigaveneleELEELRERREALENRVEALEALYDEAEELES 722
|
....
gi 1270111363 666 KFRT 669
Cdd:PRK02224 723 MYGD 726
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
222-444 |
3.12e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.08 E-value: 3.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 222 QARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEV 301
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 302 DFEHKASRFSQ---------EHEEMNAKLANQESHNRQLRLKLVG-----LSQRIEELEETNKSLQKAEEELQELRDKIA 367
Cdd:COG4942 98 ELEAQKEELAEllralyrlgRQPPLALLLSPEDFLDAVRRLQYLKylapaRREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111363 368 KgecgnssLMAEVESLRKRVlemegkDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSR 444
Cdd:COG4942 178 A-------LLAELEEERAAL------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
274-775 |
9.86e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 56.57 E-value: 9.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 274 KLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQeheeMNAKLANQESHNRQLRLKLVGLSQRIEELeetNKSLQ 353
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINN----SNNKIKILEQQIKDLNDKLKKNKDKINKL---NSDLS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 354 KAEEELQELRDKIAKGEcgnsslmAEVESLRKrvlemegkdeEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMS 433
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLE-------VELNKLEK----------QKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 434 ELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERK 513
Cdd:TIGR04523 170 ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 514 NMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEME----EKVYSLTKE-RDELMGKLRSEEERSCE 588
Cdd:TIGR04523 250 NTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKElKSELKNQEKKLEEIQNQ 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 589 LSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPED--NKIRELTLEIERLKKRLQQLEV----VEGDLMKTEDEYDQ 662
Cdd:TIGR04523 330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEkqNEIEKLKKENQSYKQEIKNLESqindLESKIQNQEKLNQQ 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 663 LEQKFRTEQDKANFLSQQLEEIKHQMAKNKAiEKGEAVSQEAELRHRFRMEEAKSRDLQAEV-----------QALKEKI 731
Cdd:TIGR04523 410 KDEQIKKLQQEKELLEKEIERLKETIIKNNS-EIKDLTNQDSVKELIIKNLDNTRESLETQLkvlsrsinkikQNLEQKQ 488
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1270111363 732 HELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKE 775
Cdd:TIGR04523 489 KELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE 532
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
312-441 |
1.37e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 56.02 E-value: 1.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 312 QEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETnksLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEME 391
Cdd:COG2433 385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQ---VERLEAEVEELEAELEEKDERIERLERELSEARSEERREI 461
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1270111363 392 GKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLqKRMSELEKLEEA 441
Cdd:COG2433 462 RKDREISRLDREIERLERELEEERERIEELKRKLERL-KELWKLEHSGEL 510
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
181-784 |
1.73e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.89 E-value: 1.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 181 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKLleQEKAYQARKEKENAKRLnkLRDELVKLKSFALMLVDERQMHIEQ 260
Cdd:pfam15921 57 YEVELDSPRKIIAYPGKEHIERVLEEYSHQVKDL--QRRLNESNELHEKQKFY--LRQSVIDLQTKLQEMQMERDAMADI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 261 LGLQSQKVQDLTQKLREEEEKLKAiTYKSKEDR----------------------QKLLKLEVDFEHKASRFSQEHEEMN 318
Cdd:pfam15921 133 RRRESQSQEDLRNQLQNTVHELEA-AKCLKEDMledsntqieqlrkmmlshegvlQEIRSILVDFEEASGKKIYEHDSMS 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 319 A----KLANQESHN-RQLRLKLVGLSQRIEELEETNKSLQ-----KAEEELQELRDK----IAKGECGNSSLMAEVESLR 384
Cdd:pfam15921 212 TmhfrSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKsesqnKIELLLQQHQDRieqlISEHEVEITGLTEKASSAR 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 385 KRVLEMEGKDEEIT-KTEAQCRELKKKLQEEEHHSKELRLEVEKlQKRMSE--LEKLEEAFSRSKSECTQLHLNLEKEKN 461
Cdd:pfam15921 292 SQANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELRE-AKRMYEdkIEELEKQLVLANSELTEARTERDQFSQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 462 LTKDLLNELEVVKSRVKELEcSESRLEKVELSLKDDLTKLKSFTvmlVDERKNMMEKIKQEERKVDGLNKNFKVE-QGKv 540
Cdd:pfam15921 371 ESGNLDDQLQKLLADLHKRE-KELSLEKEQNKRLWDRDTGNSIT---IDHLRRELDDRNMEVQRLEALLKAMKSEcQGQ- 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 541 mdvteklIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEE----RSCELSCSVDLLKKRLDGIEEVEREInrgrlc 616
Cdd:pfam15921 446 -------MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEeltaKKMTLESSERTVSDLTASLQEKERAI------ 512
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 617 kgsEFTCPEDNKIREltlEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFrTEQDKA-NFLSQQLEEIKH---QMAKNK 692
Cdd:pfam15921 513 ---EATNAEITKLRS---RVDLKLQELQHLKNEGDHLRNVQTECEALKLQM-AEKDKViEILRQQIENMTQlvgQHGRTA 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 693 AIEKGEAVSQEAELRHRfRME-----------EAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETK 761
Cdd:pfam15921 586 GAMQVEKAQLEKEINDR-RLElqefkilkdkkDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKT 664
|
650 660
....*....|....*....|...
gi 1270111363 762 NKNmgrEVLNLTKELELSKRYSR 784
Cdd:pfam15921 665 SRN---ELNSLSEDYEVLKRNFR 684
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
219-503 |
1.82e-07 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 55.82 E-value: 1.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 219 KAYQARKEKenakRLNKLRDELVKLKS---FALMLVDErqmhieQLGLQSQKVQDLTQKLReeeeKLKAITYKSKEDRQK 295
Cdd:PTZ00108 991 DLYKKRKEY----LLGKLERELARLSNkvrFIKHVING------ELVITNAKKKDLVKELK----KLGYVRFKDIIKKKS 1056
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 296 LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQriEELEETNKSLQKAEEELQELRDKIAKgecgnSS 375
Cdd:PTZ00108 1057 EKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMPIWSLTK--EKVEKLNAELEKKEKELEKLKNTTPK-----DM 1129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 376 LMAEVESLRKRVLEMEGKDEeitKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLN 455
Cdd:PTZ00108 1130 WLEDLDKFEEALEEQEEVEE---KEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEK 1206
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1270111363 456 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKS 503
Cdd:PTZ00108 1207 RKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSS 1254
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
59-769 |
2.58e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 55.36 E-value: 2.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 59 LKPSGESEKKTKKPLELSKEDLIQLLSIME-GELQAREDVIHmlKTEKTKPEVLEAHYGSAE---PEKVLRVLHRDAILA 134
Cdd:TIGR00618 148 LLPQGEFAQFLKAKSKEKKELLMNLFPLDQyTQLALMEFAKK--KSLHGKAELLTLRSQLLTlctPCMPDTYHERKQVLE 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 135 QE-KSIGEDVYEKPISE--LDRLEEKQKETYR--RMLEQLLLAEKCHRRTVYELEN---------------EKHKHTDYM 194
Cdd:TIGR00618 226 KElKHLREALQQTQQSHayLTQKREAQEEQLKkqQLLKQLRARIEELRAQEAVLEEtqerinrarkaaplaAHIKAVTQI 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 195 NK--SDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRL--------NKLRDELVKLKSFALMLVDER---------Q 255
Cdd:TIGR00618 306 EQqaQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLlqtlhsqeIHIRDAHEVATSIREISCQQHtltqhihtlQ 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 256 MHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKL 335
Cdd:TIGR00618 386 QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESA 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 336 VGLSQRIEELeETNKSLQKAEEELQELRDKIAKGECGNSSLmaevesLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEE 415
Cdd:TIGR00618 466 QSLKEREQQL-QTKEQIHLQETRKKAVVLARLLELQEEPCP------LCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 416 HHSK-------ELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECsESRLE 488
Cdd:TIGR00618 539 QLETseedvyhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC-EQHAL 617
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 489 KVELSLKDDLTKL--------KSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE 560
Cdd:TIGR00618 618 LRKLQPEQDLQDVrlhlqqcsQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 561 MEEKVYSLTKERDELMGKLRSEEERSCELSCS-VDLLKKRLDGIEEVEREINRGRlckgseftcpeDNKIRELTLEIERL 639
Cdd:TIGR00618 698 MLAQCQTLLRELETHIEEYDREFNEIENASSSlGSDLAAREDALNQSLKELMHQA-----------RTVLKARTEAHFNN 766
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 640 KKRLQQLEvvegdlmKTEDEYDQLEQKFRTEQdkanflsQQLEEIKHQMAKNKAIEKGEAVSQEAELrhrfrmeEAKSRD 719
Cdd:TIGR00618 767 NEEVTAAL-------QTGAELSHLAAEIQFFN-------RLREEDTHLLKTLEAEIGQEIPSDEDIL-------NLQCET 825
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|
gi 1270111363 720 LQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREV 769
Cdd:TIGR00618 826 LVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
178-734 |
3.59e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.67 E-value: 3.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 178 RTVYELENEKHKHTDYMNKSDDFTNLLEQE----RERLKKLLEQ-----EKAYQARKEKENAKRLNKLRDELVKLKSFAL 248
Cdd:TIGR00606 577 DWLHSKSKEINQTRDRLAKLNKELASLEQNknhiNNELESKEEQlssyeDKLFDVCGSQDEESDLERLKEEIEKSSKQRA 656
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 249 MLVDERQMH---IEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQE 325
Cdd:TIGR00606 657 MLAGATAVYsqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQ 736
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 326 SHnrqlrlklvgLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVES---LRKRVLEMEGKDEEITKTEA 402
Cdd:TIGR00606 737 SI----------IDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvCLTDVTIMERFQMELKDVER 806
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 403 Q----------------CRELKKKLQEEEHHSKELRLEVEKLQK----RMSELEKLEEAFSRSKSECTQLHLNLEKEKNL 462
Cdd:TIGR00606 807 KiaqqaaklqgsdldrtVQQVNQEKQEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQF 886
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 463 TKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDglNKNFKveqgkvMD 542
Cdd:TIGR00606 887 EEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK--NIHGY------MK 958
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 543 VTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINrgrlckgseft 622
Cdd:TIGR00606 959 DIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRE----------- 1027
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 623 cpedNKIRELTLEIERLKKRLQQLEVVEgdlmkTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMaknkaiekgeaVSQ 702
Cdd:TIGR00606 1028 ----NELKEVEEELKQHLKEMGQMQVLQ-----MKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI-----------KHF 1087
|
570 580 590
....*....|....*....|....*....|...
gi 1270111363 703 EAELRH-RFRMEEAKSRDLQAEVQALKEKIHEL 734
Cdd:TIGR00606 1088 KKELREpQFRDAEEKYREMMIVMRTTELVNKDL 1120
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
346-723 |
5.36e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 5.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 346 EETNKSLQKAEEELQELRDkiakgecgnssLMAEVESlRKRVLEMEGKD----EEItKTEAQCRELKKKLQEEEHHSKEL 421
Cdd:COG1196 175 EEAERKLEATEENLERLED-----------ILGELER-QLEPLERQAEKaeryREL-KEELKELEAELLLLKLRELEAEL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 422 RLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKL 501
Cdd:COG1196 242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 502 KsftvmlvDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRS 581
Cdd:COG1196 322 E-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 582 EEErscelscsvdlLKKRLDGIEEVEreinrgrlckgseftcpEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYD 661
Cdd:COG1196 395 AAE-----------LAAQLEELEEAE-----------------EALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 662 QLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAE 723
Cdd:COG1196 447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
190-777 |
6.29e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 54.29 E-value: 6.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 190 HTDYMNKSDDFTNLLEQERERL-KKLLEqekayqarKEKENAKRLNKLRDELvKLKSFALMLVDERQMHIEQLGLQSQKV 268
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEIGKNIELLnKEILE--------EAEINITNFNEIKEKL-KHYNFDDFGKEENIKYADEINKIKDDI 1120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 269 QDLTQKLREEEEKLKAITYKSK----EDRQKLLKLEvdfehkasrfsqeheemnaKLANQESHNRQLRlklvGLSQRIEE 344
Cdd:TIGR01612 1121 KNLDQKIDHHIKALEEIKKKSEnyidEIKAQINDLE-------------------DVADKAISNDDPE----EIEKKIEN 1177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 345 LEETNKSLQKAEEELQELRDKIAKGECGNSSL-------MAEVESLRKrvLEMEGKDEEITKTEAQCRELKKKLQEEEHh 417
Cdd:TIGR01612 1178 IVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLeevkginLSYGKNLGK--LFLEKIDEEKKKSEHMIKAMEAYIEDLDE- 1254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 418 SKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNE-LEVV-----KSRV----KELECSESRL 487
Cdd:TIGR01612 1255 IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKsLKIIedfseESDIndikKELQKNLLDA 1334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 488 EKVELSLKDDLTKLKS-FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEqgkvMDVTEKLIEESKKLLKLKsEMEEKVY 566
Cdd:TIGR01612 1335 QKHNSDINLYLNEIANiYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDE----LDKSEKLIKKIKDDINLE-ECKSKIE 1409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 567 SLTKERD---------ELMGKLRSEE-------ERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGsefTCPEDNKIR 630
Cdd:TIGR01612 1410 STLDDKDidecikkikELKNHILSEEsnidtyfKNADENNENVLLLFKNIEMADNKSQHILKIKKDNA---TNDHDFNIN 1486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 631 ELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLsqqleEIKHQMAKNKAiEKGEAVSQEAELRHRF 710
Cdd:TIGR01612 1487 ELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-----AIKNKFAKTKK-DSEIIIKEIKDAHKKF 1560
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111363 711 RMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELE 777
Cdd:TIGR01612 1561 ILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETE 1627
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
467-796 |
8.57e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 8.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 467 LNELEVVKSRVKELECSES----RLEKVE------LSLKDDLTKLKSFTVMLVDERKNMMEK-IKQEERKVDGLNKnfkv 535
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDekrqQLERLRrerekaERYQALLKEKREYEGYELLKEKEALERqKEAIERQLASLEE---- 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 536 EQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERdelMGKLRSEEErscELSCSVDLLKkrlDGIEEVEREINR--G 613
Cdd:TIGR02169 252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE---QLRVKEKIG---ELEAEIASLE---RSIAEKERELEDaeE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 614 RLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEV----VEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQM- 688
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEeyaeLKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIn 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 689 -----AKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHElmnKEDQLSQLQVDYSVLQQRFMEEETKNK 763
Cdd:TIGR02169 403 elkreLDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK---QEWKLEQLAADLSKYEQELYDLKEEYD 479
|
330 340 350
....*....|....*....|....*....|...
gi 1270111363 764 NMGREVLNLTKELELSKRYSRALRPSGNGRRMV 796
Cdd:TIGR02169 480 RVEKELSKLQRELAEAEAQARASEERVRGGRAV 512
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
338-777 |
1.00e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 53.26 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 338 LSQRIEELEETNKSLQKAEEELQELRDK----------IAKGECGNSSLMAEVESLRKRVLEMEGKDEEITkteaqcREL 407
Cdd:pfam01576 7 MQAKEEELQKVKERQQKAESELKELEKKhqqlceeknaLQEQLQAETELCAEAEEMRARLAARKQELEEIL------HEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 408 KKKLQEEEHHSKELRLEVEKLQKRMSELEKL--EEAFSRSKSECTQLHLNlEKEKNLTKDLLNELEVVKSRVKELECSES 485
Cdd:pfam01576 81 ESRLEEEEERSQQLQNEKKKMQQHIQDLEEQldEEEAARQKLQLEKVTTE-AKIKKLEEDILLLEDQNSKLSKERKLLEE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 486 RLEKVELSLKDDLTKLKSFT-------VMLVDerknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEeskkllkLK 558
Cdd:pfam01576 160 RISEFTSNLAEEEEKAKSLSklknkheAMISD----LEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAE-------LQ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 559 SEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSeftcpEDNKIRELTLEIER 638
Cdd:pfam01576 229 AQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRRDLGEELEA 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 639 LK------------------KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKA-NFLSQQLEEIKH---QMAKNKAIEK 696
Cdd:pfam01576 304 LKteledtldttaaqqelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRnkaNLEKAKQALE 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 697 GEAVSQEAELR----------HRFRMEEAKSRDLQAEVQALKEKIHELmnkEDQLSQLQVDYSVLQQRFMEEETKNKNMG 766
Cdd:pfam01576 384 SENAELQAELRtlqqakqdseHKRKKLEGQLQELQARLSESERQRAEL---AEKLSKLQSELESVSSLLNEAEGKNIKLS 460
|
490
....*....|.
gi 1270111363 767 REVLNLTKELE 777
Cdd:pfam01576 461 KDVSSLESQLQ 471
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
148-710 |
1.32e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 52.98 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 148 ISELDRLEEKQKETYRRMLE---QLLLAEKCHRRTVYELENEKhkhTDYMNKSDDFtNLLEQERERLKKLLEQEKAYQAr 224
Cdd:PRK01156 182 ISNIDYLEEKLKSSNLELENikkQIADDEKSHSITLKEIERLS---IEYNNAMDDY-NNLKSALNELSSLEDMKNRYES- 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 225 KEKENAKRLNKLRDELVKLKSfalmlVDERQMHIE-------------------QLGLQSQKVQDLTQKLREEEEKLK-- 283
Cdd:PRK01156 257 EIKTAESDLSMELEKNNYYKE-----LEERHMKIIndpvyknrnyindyfkyknDIENKKQILSNIDAEINKYHAIIKkl 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 284 AITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLR------LKLVGLSQRIEELEETNKSLQKAEe 357
Cdd:PRK01156 332 SVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEeyskniERMSAFISEILKIQEIDPDAIKKE- 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 358 eLQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEE--EHHSKELRLEVEKLQKRMSEL 435
Cdd:PRK01156 411 -LNEINVKLQDISSKVSSLNQRIRALRENLDELS-RNMEMLNGQSVCPVCGTTLGEEksNHIINHYNEKKSRLEEKIREI 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 436 EKLEEAFSRSKSECTQLHLNLEKEK-NLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERK- 513
Cdd:PRK01156 489 EIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRt 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 514 ---NMMEKIKQEErkVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS-------EMEEKVYSLTKERDELMGKLRSEE 583
Cdd:PRK01156 569 swlNALAVISLID--IETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSyidksirEIENEANNLNNKYNEIQENKILIE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 584 ErsceLSCSVDLLKKRLDGIEEVEREINrgrlckgseftcpednkirELTLEIERLKKRLQQlevVEGDLMKTEDEYDQL 663
Cdd:PRK01156 647 K----LRGKIDNYKKQIAEIDSIIPDLK-------------------EITSRINDIEDNLKK---SRKALDDAKANRARL 700
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1270111363 664 EQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKgeAVSQEAELRHRF 710
Cdd:PRK01156 701 ESTIEILRTRINELSDRINDINETLESMKKIKK--AIGDLKRLREAF 745
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
73-777 |
1.66e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 52.48 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 73 LELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEV----LEAHYGSAE--------------------PEKVLRVLH 128
Cdd:pfam01576 66 LAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQhiqdLEEQLDEEEaarqklqlekvtteakikklEEDILLLED 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 129 RDAILAQEKSIGEDVYEKPISELDRLEEKQKE------TYRRMLEQLLLAEKCHRRTVYELENEKHkhtdymnKSDDFTN 202
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEKAKSlsklknKHEAMISDLEERLKKEEKGRQELEKAKR-------KLEGEST 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 203 LLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKlKSFALMLVDERQMHIEQLG-------LQSQKVQDLTQKL 275
Cdd:pfam01576 219 DLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQ-KNNALKKIRELEAQISELQedleserAARNKAEKQRRDL 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 276 REEEEKLKA-------ITYKSKEDR----QKLLKLEVDFEHKASRFSQEHEEMNAKlanqesHNRQlrlkLVGLSQRIEE 344
Cdd:pfam01576 298 GEELEALKTeledtldTTAAQQELRskreQEVTELKKALEEETRSHEAQLQEMRQK------HTQA----LEELTEQLEQ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 345 LEETNKSLQKAEEELqelrdkiakgECGNSSLMAEVESLRKRVLEMEGKDEeitKTEAQCRELKKKLQEEEHHSKELrle 424
Cdd:pfam01576 368 AKRNKANLEKAKQAL----------ESENAELQAELRTLQQAKQDSEHKRK---KLEGQLQELQARLSESERQRAEL--- 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 425 VEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDllnelevvksrVKELECSESRlEKVELSlkddlTKLKSf 504
Cdd:pfam01576 432 AEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQD-----------TQELLQEETR-QKLNLS-----TRLRQ- 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 505 tvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLlklkSEMEEKVYSLTKERDELMGKLRSEEE 584
Cdd:pfam01576 494 ---LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL----EALEEGKKRLQRELEALTQQLEEKAA 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 585 rscelscSVDLLKKrldgieevereiNRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDL-MKTEDEYDQL 663
Cdd:pfam01576 567 -------AYDKLEK------------TKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAIsARYAEERDRA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 664 EQKFRTEQDKANFLSQQLEEIKHQMAK----NKAI--EKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNK 737
Cdd:pfam01576 628 EAEAREKETRALSLARALEEALEAKEElertNKQLraEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDE 707
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 738 ----EDQLSQLQVDYSVLQQRFMEE--------ETKNKNMGREVLNLTKELE 777
Cdd:pfam01576 708 lqatEDAKLRLEVNMQALKAQFERDlqardeqgEEKRRQLVKQVRELEAELE 759
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
259-781 |
1.82e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 52.48 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 259 EQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSqEHEEMNAKLANQEshnRQLRLKLVGL 338
Cdd:pfam01576 5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCA-EAEEMRARLAARK---QELEEILHEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 339 SQRIEELEETNKSLQ----KAEEELQELRDKIAKGECGNSSLM-------AEVESLRKRVLEMEGKDEEITKT----EAQ 403
Cdd:pfam01576 81 ESRLEEEEERSQQLQnekkKMQQHIQDLEEQLDEEEAARQKLQlekvtteAKIKKLEEDILLLEDQNSKLSKErkllEER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 404 CRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECS 483
Cdd:pfam01576 161 ISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL---QAQIAELRAQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 484 esrLEKVELSLKDDLTKLKSFTVmlvdERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 563
Cdd:pfam01576 238 ---LAKKEEELQAALARLEEETA----QKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELED 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 564 KVYSLTKERDelmgkLRSEEERScelscsVDLLKKRLDgieeverEINRGRLCKGSEFTCPEDNKIRELTLEIERLKKRL 643
Cdd:pfam01576 311 TLDTTAAQQE-----LRSKREQE------VTELKKALE-------EETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNK 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 644 QQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI--KHQMAKNKAIEKGEAVSQ-EAELR---HRFRME 713
Cdd:pfam01576 373 ANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqaRLSESERQRAELAEKLSKlQSELEsvsSLLNEA 452
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1270111363 714 EAKSRDLQAEVQALKEKIH---ELMNKEDQ--------LSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELELSKR 781
Cdd:pfam01576 453 EGKNIKLSKDVSSLESQLQdtqELLQEETRqklnlstrLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
22-755 |
2.57e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.15 E-value: 2.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 22 SIISSDGGKGPSEDAKKNKANRKGED-DVMASGTVKRHLKPSGESEKKTKKPLELSkedliqlLSIMEGELQAREDVIHM 100
Cdd:pfam12128 204 AILEDDGVVPPKSRLNRQQVEHWIRDiQAIAGIMKIRPEFTKLQQEFNTLESAELR-------LSHLHFGYKSDETLIAS 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 101 LKTEKTKpevleahyGSAEPEKVLRVLHRD-----AILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLaekc 175
Cdd:pfam12128 277 RQEERQE--------TSAELNQLLRTLDDQwkekrDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAA---- 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 176 hrrtvyELENEkhkhtdymnksDDFTNLLEQERERLKKLLEQ----EKAYQARKEK---ENAKRLNKLRDELVKLKSFAL 248
Cdd:pfam12128 345 ------DQEQL-----------PSWQSELENLEERLKALTGKhqdvTAKYNRRRSKikeQNNRDIAGIKDKLAKIREARD 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 249 MLVDERQMHIEQL----------GLQSQKVQDLTQKLREEEEKLK--AITYKSKEDRQKllklevdfEHKASRFSQEHEE 316
Cdd:pfam12128 408 RQLAVAEDDLQALeselreqleaGKLEFNEEEYRLKSRLGELKLRlnQATATPELLLQL--------ENFDERIERAREE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 317 MNAKLANQES--------------HNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVES 382
Cdd:pfam12128 480 QEAANAEVERlqselrqarkrrdqASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPEL 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 383 LRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEH-----HSKELRLEVEKL----------QKRMSE--------LEKLE 439
Cdd:pfam12128 560 LHRTDLDPE-VWDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAeealqsarekQAAAEEqlvqangeLEKAS 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 440 EAFSRSKSECTQLHLNLEKEKNLTKDLlnELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDE-RKNMMEK 518
Cdd:pfam12128 639 REETFARTALKNARLDLRRLFDEKQSE--KDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQkREARTEK 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 519 ikQEERKVdglnknfkVEQGKvmDVTEKLIEESKklLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK 598
Cdd:pfam12128 717 --QAYWQV--------VEGAL--DAQLALLKAAI--AARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLER 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 599 RLDGIEEVEREINRGRLCKGSEFTCPEDN----------KIRELTLEIERL----KKRLQQLEVVEGDLMKTEDEYDQLE 664
Cdd:pfam12128 783 KIERIAVRRQEVLRYFDWYQETWLQRRPRlatqlsnierAISELQQQLARLiadtKLRRAKLEMERKASEKQQVRLSENL 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 665 QKFRTEQDKANFLS--QQLEEIKHQMAKN-------KAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEV-QALKEKIHEL 734
Cdd:pfam12128 863 RGLRCEMSKLATLKedANSEQAQGSIGERlaqledlKLKRDYLSESVKKYVEHFKNVIADHSGSGLAETwESLREEDHYQ 942
|
810 820
....*....|....*....|.
gi 1270111363 735 MNKEDQLSQLQVDYSVLQQRF 755
Cdd:pfam12128 943 NDKGIRLLDYRKLVPYLEQWF 963
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
274-737 |
3.22e-06 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 51.38 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 274 KLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEM-NAKLANQESHnrqlrlklvglsqrIEELEETNKS- 351
Cdd:PRK04778 33 ELEERKQELENLPVNDELEKVKKLNLTGQSEEKFEEWRQKWDEIvTNSLPDIEEQ--------------LFEAEELNDKf 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 352 -LQKAEEELQELRDKIAKGEcgnsslmAEVESLRKRVLEMEGKDE----EITKTEAQCRELKKKLQEEEHHSKELrleVE 426
Cdd:PRK04778 99 rFRKAKHEINEIESLLDLIE-------EDIEQILEELQELLESEEknreEVEQLKDLYRELRKSLLANRFSFGPA---LD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 427 KLQKRMSELEKLEEAFSRSKSE--CTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcsesrlekveLSLKDDLTKLKS- 503
Cdd:PRK04778 169 ELEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAALEQIMEEIPELLKELQ----------TELPDQLQELKAg 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 504 FTVMLVD----ERKNMMEKIKQEERKVDGLNKNfkVEQGKVMDVTEKLIEESKKLLKLKSEMEEKV---YSLTKERDELM 576
Cdd:PRK04778 239 YRELVEEgyhlDHLDIEKEIQDLKEQIDENLAL--LEELDLDEAEEKNEEIQERIDQLYDILEREVkarKYVEKNSDTLP 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 577 GKLRSEEERSCELSCSVDLLKKR-------LDGIEEVEREINRgrlckgseftcpednkIRELTLEI------------- 636
Cdd:PRK04778 317 DFLEHAKEQNKELKEEIDRVKQSytlneseLESVRQLEKQLES----------------LEKQYDEIteriaeqeiayse 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 637 --ERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK--------------NKAIEKGEAV 700
Cdd:PRK04778 381 lqEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNKLHEIKRYLEKsnlpglpedylemfFEVSDEIEAL 460
|
490 500 510
....*....|....*....|....*....|....*....
gi 1270111363 701 SQEAElRHRFRMEE--AKSRDLQAEVQALKEKIHELMNK 737
Cdd:PRK04778 461 AEELE-EKPINMEAvnRLLEEATEDVETLEEETEELVEN 498
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
272-489 |
3.32e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 3.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 272 TQKLREEEEKLKAITYKSKEDRQKLLKLEVdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEetnKS 351
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE---KE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 352 LQKAEEELQELRDKIAK--------GECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL 423
Cdd:COG4942 92 IAELRAELEAQKEELAEllralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 424 EVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECSESRLEK 489
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL---QQEAEELEALIARLEA 234
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
334-737 |
3.67e-06 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 51.01 E-value: 3.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 334 KLVGLSQRIEELEETNKS--LQKAEEELQELRDKIAKGEcgnsslmAEVESLRKRVLEMEGKDE----EITKTEAQCREL 407
Cdd:pfam06160 61 SLPDIEELLFEAEELNDKyrFKKAKKALDEIEELLDDIE-------EDIKQILEELDELLESEEknreEVEELKDKYREL 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 408 KKKLQEEEHHSKELrleVEKLQKRMSELEKLEEAFSRSKSECtqlhlNLEKEKNLTKDLLNELEVVKSRVKELEcseSRL 487
Cdd:pfam06160 134 RKTLLANRFSYGPA---IDELEKQLAEIEEEFSQFEELTESG-----DYLEAREVLEKLEEETDALEELMEDIP---PLY 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 488 EKVELSLKDDLTKLKS-FTVMLVD----ERKNMMEKIKQEERKVDGLNKNFK------VEQG---------KVMDVTEKL 547
Cdd:pfam06160 203 EELKTELPDQLEELKEgYREMEEEgyalEHLNVDKEIQQLEEQLEENLALLEnleldeAEEAleeieeridQLYDLLEKE 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 548 IEESKKLLKLKSEMEEKVYSLTKERDELMGKLR----------SEEERSCELSCSVDLLKKRLDGIEEVEreinrgrlck 617
Cdd:pfam06160 283 VDAKKYVEKNLPEIEDYLEHAEEQNKELKEELErvqqsytlneNELERVRGLEKQLEELEKRYDEIVERL---------- 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 618 gseftcpEDNKIRELTLEiERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK------- 690
Cdd:pfam06160 353 -------EEKEVAYSELQ-EELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLELREIKRLVEKsnlpglp 424
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 691 -------NKAIEKGEAVSQEAElRHRFRMEE--AKSRDLQAEVQALKEKIHELMNK 737
Cdd:pfam06160 425 esyldyfFDVSDEIEDLADELN-EVPLNMDEvnRLLDEAQDDVDTLYEKTEELIDN 479
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
291-445 |
4.00e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.54 E-value: 4.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 291 EDRQKLLKLEvDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEetnKSLQKAEEELQELRDKIAK-- 368
Cdd:COG1579 4 EDLRALLDLQ-ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLE---KEIKRLELEIEEVEARIKKye 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 369 ---GECGNS----SLMAEVESLRKR--VLE---------MEGKDEEITKTEAQCRELKKKLQEEEhhsKELRLEVEKLQK 430
Cdd:COG1579 80 eqlGNVRNNkeyeALQKEIESLKRRisDLEdeilelmerIEELEEELAELEAELAELEAELEEKK---AELDEELAELEA 156
|
170
....*....|....*
gi 1270111363 431 RMSELEKLEEAFSRS 445
Cdd:COG1579 157 ELEELEAEREELAAK 171
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
264-503 |
4.37e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 50.78 E-value: 4.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 264 QSQKVQDLTQKLREEEEKLKaiTYKSKEDRQkllklevdfEHKASRFSQEHEEMNAKLANQESHNRQLrlklvgLSQRIE 343
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIK--TYNKNIEEQ---------RKKNGENIARKQNKYDELVEEAKTIKAE------IEELTD 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 344 ELEETNKSLQKAEEELQELRDKIAKgecgnssLMAEVESLRKrVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRL 423
Cdd:PHA02562 242 ELLNLVMDIEDPSAALNKLNTAAAK-------IKSKIEQFQK-VIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 424 EVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcSESRLEKVELS-LKDDLTKLK 502
Cdd:PHA02562 314 SLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ-AEFVDNAEELAkLQDELDKIV 392
|
.
gi 1270111363 503 S 503
Cdd:PHA02562 393 K 393
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
356-788 |
5.82e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.54 E-value: 5.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 356 EEELQELRDKIAKGECGNSSL-MAEVESLRKRVlemegkdEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSE 434
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELnLKELKELEEEL-------KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 435 LEKLEEAFSRSKsECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKddlTKLKSFTVMLVDERKN 514
Cdd:COG4717 121 LEKLLQLLPLYQ-ELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELE---ELLEQLSLATEEELQD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 515 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLksEMEEKVY-------------SLTKERDELMG---- 577
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA--ALEERLKearlllliaaallALLGLGGSLLSlilt 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 578 ------------------------KLRSEEERSCELSCSVDLLKKRLDGIEEvEREINRGRLCKGSEFTCPEDNKIRELT 633
Cdd:COG4717 275 iagvlflvlgllallflllarekaSLGKEAEELQALPALEELEEEELEELLA-ALGLPPDLSPEELLELLDRIEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 634 LEIERLKKRLQQL-------EVVEGDLMKTEDEYDQLEQKFRTEQDkanfLSQQLEEIKHQM-AKNKAIEKGEAVSQEAE 705
Cdd:COG4717 354 REAEELEEELQLEeleqeiaALLAEAGVEDEEELRAALEQAEEYQE----LKEELEELEEQLeELLGELEELLEALDEEE 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 706 LRHRFRMEEAKSRDLQAEVQALKEKIHELmnkEDQLSQLQVD--YSVLQQRFMEEETKNKNMGRE--VLNLTKEL--ELS 779
Cdd:COG4717 430 LEEELEELEEELEELEEELEELREELAEL---EAELEQLEEDgeLAELLQELEELKAELRELAEEwaALKLALELleEAR 506
|
....*....
gi 1270111363 780 KRYSRALRP 788
Cdd:COG4717 507 EEYREERLP 515
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
182-772 |
8.63e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 50.43 E-value: 8.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 182 ELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQL 261
Cdd:TIGR00606 232 QLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRK--KQMEKDNSELELKMEKVFQGTDEQLNDLYHN 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 262 glQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKlaNQESHNRQLRLKLVGLsQR 341
Cdd:TIGR00606 310 --HQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRAR--DSLIQSLATRLELDGF-ER 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 342 IEELEETNKSLQKAEEELQELRDKIAKGECGN--SSLMAEVESLRKRVLEMEG-------KDEEITKTEAQCRELKKKLQ 412
Cdd:TIGR00606 385 GPFSERQIKNFHTLVIERQEDEAKTAAQLCADlqSKERLKQEQADEIRDEKKGlgrtielKKEILEKKQEELKFVIKELQ 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 413 EEEHHSKELRLEVEKLQKRMSELEKLEEafsRSKSECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVEL 492
Cdd:TIGR00606 465 QLEGSSDRILELDQELRKAERELSKAEK---NSLTET--LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 493 SLKDDLT------KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 566
Cdd:TIGR00606 540 LTKDKMDkdeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEE 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 567 SLTKERDELMGKLRSEEERScelscSVDLLKKRLdgieeverEINRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQL 646
Cdd:TIGR00606 620 QLSSYEDKLFDVCGSQDEES-----DLERLKEEI--------EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 647 EVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQM---AKNKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAE 723
Cdd:TIGR00606 687 FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlglAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND 766
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1270111363 724 VQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNL 772
Cdd:TIGR00606 767 IEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL 815
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
202-417 |
8.81e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 50.01 E-value: 8.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 202 NLLEQERERLKKLLEQEKAyqarKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEK 281
Cdd:PHA02562 191 DHIQQQIKTYNKNIEEQRK----KNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 282 LKAitykskeDRQKLLKLEVDFE--HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEEL 359
Cdd:PHA02562 267 IKS-------KIEQFQKVIKMYEkgGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKL 339
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111363 360 QELRDKIAKGECGNSSLMAEVESLRKRVLEMEG----KDEEITKTEAQCRELKKKLQE---EEHH 417
Cdd:PHA02562 340 LELKNKISTNKQSLITLVDKAKKVKAAIEELQAefvdNAEELAKLQDELDKIVKTKSElvkEKYH 404
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
298-675 |
1.39e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.58 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 298 KLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKgecgnsslm 377
Cdd:pfam02463 155 RLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY--------- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 378 aeVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLE 457
Cdd:pfam02463 226 --LLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 458 KEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKvdglnknfkveQ 537
Cdd:pfam02463 304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL-----------E 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 538 GKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSvdllKKRLDGIEEVEREINRGRLCK 617
Cdd:pfam02463 373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE----ELEILEEEEESIELKQGKLTE 448
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111363 618 GSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKAN 675
Cdd:pfam02463 449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-351 |
1.57e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 149 SELDRLEEKQKETyRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKE 228
Cdd:COG4942 27 AELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 229 NAKRLNKL---------------RDELVKLKSFALM--LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKE 291
Cdd:COG4942 106 LAELLRALyrlgrqpplalllspEDFLDAVRRLQYLkyLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 292 DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKS 351
Cdd:COG4942 186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
338-765 |
1.70e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 49.13 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 338 LSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEhh 417
Cdd:PRK01156 192 LKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMEL-- 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 418 skelrLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLekeKNLTKDLLNELEVVKSRVKELECSESRLEKVElSLKDD 497
Cdd:PRK01156 270 -----EKNNYYKELEERHMKIINDPVYKNRNYINDYFKY---KNDIENKKQILSNIDAEINKYHAIIKKLSVLQ-KDYND 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 498 LTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMG 577
Cdd:PRK01156 341 YIKKKS----RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINV 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 578 KLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCK--GSEFTCPEDNKIRE-LTLEIERLKKRLQQLEVVEGDLm 654
Cdd:PRK01156 417 KLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPvcGTTLGEEKSNHIINhYNEKKSRLEEKIREIEIEVKDI- 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 655 kTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHrfrmEEAKSRDLQAEVQALKEKIHEL 734
Cdd:PRK01156 496 -DEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKY----EEIKNRYKSLKLEDLDSKRTSW 570
|
410 420 430
....*....|....*....|....*....|.
gi 1270111363 735 MNKEDQLSQLQVDysVLQQRFMEEETKNKNM 765
Cdd:PRK01156 571 LNALAVISLIDIE--TNRSRSNEIKKQLNDL 599
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
374-605 |
1.79e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 374 SSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRSKSEC 449
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaaLEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 450 TQLHLNLEKEKNLTKDLLNELEVVkSRVKELecsesrleKVELSLKDDLTKLKSFTVM--LVDERKNMMEKIKQEERKVD 527
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRL-GRQPPL--------ALLLSPEDFLDAVRRLQYLkyLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111363 528 GLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEE 605
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
312-728 |
1.92e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 48.53 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 312 QEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEME 391
Cdd:pfam19220 3 QRNELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 392 GkdeEITKTEAQCRELKKKLQEEEHHSKELRLEvekLQKRMSELEKLEeafsrsksecTQLHLNLEKEKNLT---KDLLN 468
Cdd:pfam19220 83 G---ELEELVARLAKLEAALREAEAAKEELRIE---LRDKTAQAEALE----------RQLAAETEQNRALEeenKALRE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 469 ELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSftvmLVDErknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLI 548
Cdd:pfam19220 147 EAQAAEKALQRAEGELATARERLALLEQENRRLQA----LSEE---QAAELAELTRRLAELETQLDATRARLRALEGQLA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 549 EESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRgrlckgseftcpednK 628
Cdd:pfam19220 220 AEQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAER---------------R 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 629 IRELTLEIERLKKRlqqLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEeikhqmAKNKAIEKGE---AVSQE-- 703
Cdd:pfam19220 285 LKEASIERDTLERR---LAGLEADLERRTQQFQEMQRARAELEERAEMLTKALA------AKDAALERAEeriASLSDri 355
|
410 420
....*....|....*....|....*....
gi 1270111363 704 AELRHRFRME----EAKSRDLQAEVQALK 728
Cdd:pfam19220 356 AELTKRFEVEraalEQANRRLKEELQRER 384
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
152-527 |
2.28e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 48.35 E-value: 2.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 152 DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE----KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQArkek 227
Cdd:pfam07888 54 NRQREKEKERYKRDREQWERQRRELESRVAELKEElrqsREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEA---- 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 228 enakRLNKLRDELVKLKSFALmlvdERQMHIEQLglqSQKVQDLTQKLREEEEklkaitykskEDRQKLLKLEVDfEHKA 307
Cdd:pfam07888 130 ----RIRELEEDIKTLTQRVL----ERETELERM---KERAKKAGAQRKEEEA----------ERKQLQAKLQQT-EEEL 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 308 SRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESL---R 384
Cdd:pfam07888 188 RSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMaaqR 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 385 KRVL-EMEGKDEEITKTEAQCRELKKKLQEEEHHSKELR--------LEVEKLQKRMSELEKLEEAFSRSKSECTQLHLN 455
Cdd:pfam07888 268 DRTQaELHQARLQAAQLTLQLADASLALREGRARWAQERetlqqsaeADKDRIEKLSAELQRLEERLQEERMEREKLEVE 347
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 456 LEKEKNLtkdllnelevvkSRVkelECSESRLEKVElsLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 527
Cdd:pfam07888 348 LGREKDC------------NRV---QLSESRRELQE--LKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
266-588 |
2.30e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.60 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 266 QKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLevdfEHKASRFSQEHEEMNAKLanqeshnRQLRLKlvgLSQRIEEL 345
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKRDEL----NEELKELAEKRDELNAQV-------KELREE---AQELREKR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 346 EETNKSLQKAEEELQELRDKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEV 425
Cdd:COG1340 67 DELNEKVKELKEERDELNEKL-------NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELV 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 426 EKLQKRMSELEKLEEAfsrsksectqlhlnlEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFT 505
Cdd:COG1340 140 EKIKELEKELEKAKKA---------------LEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEA 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 506 VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKvySLTKERDELMGKLRSEEER 585
Cdd:COG1340 205 DELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKE--ELEEKAEEIFEKLKKGEKL 282
|
...
gi 1270111363 586 SCE 588
Cdd:COG1340 283 TTE 285
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
150-421 |
2.33e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.58 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 150 ELDRL-EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKsddftnllEQERERLKKLLEQEKAyqaRKEKE 228
Cdd:pfam17380 349 ELERIrQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQ--------ELEAARKVKILEEERQ---RKIQQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 229 NAKRLNKLRDELVKLKSFAL-MLVDERQMHIEQLGLQSQKVQDLTQKLREEEEklkaitykskEDRQKLLKLEvdfehKA 307
Cdd:pfam17380 418 QKVEMEQIRAEQEEARQREVrRLEEERAREMERVRLEEQERQQQVERLRQQEE----------ERKRKKLELE-----KE 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 308 SRFSQEHEEMNAKLANQESHNRQlrlklvglsQRIEELEETNKSLQKAEEELQ-----ELRDKIAKGECGNSSLMAEves 382
Cdd:pfam17380 483 KRDRKRAEEQRRKILEKELEERK---------QAMIEEERKRKLLEKEMEERQkaiyeEERRREAEEERRKQQEMEE--- 550
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1270111363 383 lRKRVLE-MEGKDEEITKTEA--QCRELKKKLQEEEHHSKEL 421
Cdd:pfam17380 551 -RRRIQEqMRKATEERSRLEAmeREREMMRQIVESEKARAEY 591
|
|
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
395-513 |
2.34e-05 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 46.44 E-value: 2.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 395 EEITKTEAQCRELKKKLQEeehhskeLRLEVEKLQKRMS---ELEKLEEAFSRSKSECTQLHLNLEKEKnltkdLLNELE 471
Cdd:pfam09727 80 AELEKLVEKQRETQRRMLE-------QLAAAEKRHRRVIrelEEEKRKHARDTAQGDDFTYLLEKERER-----LKQELE 147
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1270111363 472 VVKSRVKELEcseSRLEKVELSLKDDLTKLKSFTVMLVDERK 513
Cdd:pfam09727 148 QEKAQQKRLE---KELKKLLEKLEEELSKQKQIALLLVKERK 186
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
284-442 |
2.85e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 48.32 E-value: 2.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 284 AITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQ----ESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEEL 359
Cdd:COG2433 381 ALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQverlEAEVEELEAELEEKDERIERLERELSEARSEERRE 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 360 QELRDKIakgecgnSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLqeeehHSKELR--LEVEKLQKrmSELEK 437
Cdd:COG2433 461 IRKDREI-------SRLDREIERLERELEEERERIEELKRKLERLKELWKLE-----HSGELVpvKVVEKFTK--EAIRR 526
|
....*
gi 1270111363 438 LEEAF 442
Cdd:COG2433 527 LEEEY 531
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
204-784 |
3.03e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 48.63 E-value: 3.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 204 LEQERERLKKLLEQEKAYQARKEKEnaKRlnKLRDELVKLKSfalMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 283
Cdd:pfam01576 269 LEAQISELQEDLESERAARNKAEKQ--RR--DLGEELEALKT---ELEDTLDTTAAQQELRSKREQEVTELKKALEEETR 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 284 AITYKSKEDRQK----LLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLKLVGLSQRIEELEETNKslqKAEEEL 359
Cdd:pfam01576 342 SHEAQLQEMRQKhtqaLEELTEQLE-QAKRNKANLEKAKQAL---ESENAELQAELRTLQQAKQDSEHKRK---KLEGQL 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 360 QELRDKIAKGECGN-------SSLMAEVESLRKRVLEMEGKD----EEITKTEAQCRELKKKLQEEEHH-----SKELRL 423
Cdd:pfam01576 415 QELQARLSESERQRaelaeklSKLQSELESVSSLLNEAEGKNiklsKDVSSLESQLQDTQELLQEETRQklnlsTRLRQL 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 424 EVEK--LQKRMSELEKLEEAFSR-----------SKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKV 490
Cdd:pfam01576 495 EDERnsLQEQLEEEEEAKRNVERqlstlqaqlsdMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 491 ELSLKDDLTKLksftVMLVDERKNMMEKIKQEERKVDGLNKNFKVeqgkvmdVTEKLIEESKKLLKLKSEMEEKVYSLTK 570
Cdd:pfam01576 575 KNRLQQELDDL----LVDLDHQRQLVSNLEKKQKKFDQMLAEEKA-------ISARYAEERDRAEAEAREKETRALSLAR 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 571 ERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRlckgseftcpednkiRELTLEIERLKkrlQQLEVVE 650
Cdd:pfam01576 644 ALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSK---------------RALEQQVEEMK---TQLEELE 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 651 GDLMKTEDEYDQLE---QKFRTEQDK-ANFLSQQLEEIKHQMAKN---KAIEKGEAVSQEAELRHRFRMEEAKSRDLQAE 723
Cdd:pfam01576 706 DELQATEDAKLRLEvnmQALKAQFERdLQARDEQGEEKRRQLVKQvreLEAELEDERKQRAQAVAAKKKLELDLKELEAQ 785
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 724 VQAL----KEKIHELMNKEDQLSQLQVDYSVLQQ-------RFMEEETKNKNMGREVLNLTKELELSKRYSR 784
Cdd:pfam01576 786 IDAAnkgrEEAVKQLKKLQAQMKDLQRELEEARAsrdeilaQSKESEKKLKNLEAELLQLQEDLAASERARR 857
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
429-764 |
4.36e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 4.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 429 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL----EKVELSLKDDLTKLKSf 504
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLyldyLKLNEERIDLLQELLR- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 505 tvMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL------MGK 578
Cdd:pfam02463 248 --DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesekeKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 579 LRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTED 658
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 659 EYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKGEAVSQEAELRHRFRMEEAKSRDL-QAEVQALKEKIHELMNK 737
Cdd:pfam02463 406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELkKSEDLLKETQLVKLQEQ 485
|
330 340
....*....|....*....|....*..
gi 1270111363 738 EDQLSQLQVDYSVLQQRFMEEETKNKN 764
Cdd:pfam02463 486 LELLLSRQKLEERSQKESKARSGLKVL 512
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
262-553 |
4.49e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 47.97 E-value: 4.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 262 GLQSQKVQDLTQKLREEEEK---LKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--KLANQE-SHNRQLRLKL 335
Cdd:PLN02939 124 QLSDFQLEDLVGMIQNAEKNillLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDAriKLAAQEkIHVEILEEQL 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 336 VGLSQRIEELEETNKSLQKA-EEELQELRDKiakgecgNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEE 414
Cdd:PLN02939 204 EKLRNELLIRGATEGLCVHSlSKELDVLKEE-------NMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLREL 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 415 EHHSKELRLEVEKLQKR-----MSELEKLEEAFSRSKSECTQLHLNLEKEKnltkDLLNELEVVKSRVKELECSESRLEK 489
Cdd:PLN02939 277 ESKFIVAQEDVSKLSPLqydcwWEKVENLQDLLDRATNQVEKAALVLDQNQ----DLRDKVDKLEASLKEANVSKFSSYK 352
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111363 490 VELSLKddltKLKsftvmLVDERknmMEKIKQEERKVDGLNKNFKVEqgkVMDVTEKLIEESKK 553
Cdd:PLN02939 353 VELLQQ----KLK-----LLEER---LQASDHEIHSYIQLYQESIKE---FQDTLSKLKEESKK 401
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
508-747 |
4.63e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 46.83 E-value: 4.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 508 LVDERKNMMEKIKQEERKVDGLN---KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEE 584
Cdd:COG1340 13 LEEKIEELREEIEELKEKRDELNeelKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELRE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 585 RSCELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEdnKIRELTLEIERLKKRLQQLEV---VEGDLMKTEDEYD 661
Cdd:COG1340 93 ELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPE--EEKELVEKIKELEKELEKAKKaleKNEKLKELRAELK 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 662 QLEQKFRTEQDKANFLSQQLEEIKHQMAKNKaiEKGEAVSQEA-ELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQ 740
Cdd:COG1340 171 ELRKEAEEIHKKIKELAEEAQELHEEMIELY--KEADELRKEAdELHKEIVEAQEKADELHEEIIELQKELRELRKELKK 248
|
....*..
gi 1270111363 741 LSQLQVD 747
Cdd:COG1340 249 LRKKQRA 255
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
517-742 |
4.92e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 47.32 E-value: 4.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 517 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDEL---MGKLRSEEERscelscsv 593
Cdd:PHA02562 195 QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPsaaLNKLNTAAAK-------- 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 594 dlLKKRLDGIEEVEREINRGRLCKgsefTC-----PEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 668
Cdd:PHA02562 267 --IKSKIEQFQKVIKMYEKGGVCP----TCtqqisEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL 340
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111363 669 TEQDKanfLSQQLEEIKHQMAKNKAIEKgeaVSQEAELRHRFRMEEAKSrdLQAEVQALKEKIHELMNKEDQLS 742
Cdd:PHA02562 341 ELKNK---ISTNKQSLITLVDKAKKVKA---AIEELQAEFVDNAEELAK--LQDELDKIVKTKSELVKEKYHRG 406
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
352-527 |
5.51e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.07 E-value: 5.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 352 LQKAEEELQELRDKIAKgecgnssLMAEVESLRKrvlEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKR 431
Cdd:COG1579 12 LQELDSELDRLEHRLKE-------LPAELAELED---ELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 432 MSELEKLEEAFSRSKsECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLEKVELSLKDDLTKLKSFTVMLVDE 511
Cdd:COG1579 82 LGNVRNNKEYEALQK-EIESLKRRISDLEDEILELMERIEELEEELAEL---EAELAELEAELEEKKAELDEELAELEAE 157
|
170
....*....|....*.
gi 1270111363 512 RKNMMEKIKQEERKVD 527
Cdd:COG1579 158 LEELEAEREELAAKIP 173
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
212-437 |
6.45e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 6.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 212 KKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDErqmHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKskE 291
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPE---ELLELLDRIEELQELLREAEELEEELQLEELE--Q 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 292 DRQKLLKL-----EVDFEHKASRFSQEHE------EMNAKLANQESHNRQLrLKLVGLSQRIEELEETNKSLQKAEEELQ 360
Cdd:COG4717 371 EIAALLAEagvedEEELRAALEQAEEYQElkeeleELEEQLEELLGELEEL-LEALDEEELEEELEELEEELEELEEELE 449
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111363 361 ELRDKIAKgecgnsslmaevesLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK 437
Cdd:COG4717 450 ELREELAE--------------LEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
635-757 |
7.90e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 635 EIERLKKRLQQLEVvegdlmktedEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKnkaiekgEAVSQEAELRHRFRMEE 714
Cdd:COG3206 264 VIQQLRAQLAELEA----------ELAELSARYTPNHPDVIALRAQIAALRAQLQQ-------EAQRILASLEAELEALQ 326
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1270111363 715 AKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 757
Cdd:COG3206 327 AREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
355-588 |
8.16e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 8.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 355 AEEELQELRDKIakgecgnSSLMAEVESLRKRVLEMegkDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSE 434
Cdd:COG3883 14 ADPQIQAKQKEL-------SELQAELEAAQAELDAL---QAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 435 LEKLEEAFSRSKSEctqlhlnlekeknlTKDLLNELEVVKSrvkelecSEsrlekvelSLKDDLTKLKSFTvMLVDERKN 514
Cdd:COG3883 84 RREELGERARALYR--------------SGGSVSYLDVLLG-------SE--------SFSDFLDRLSALS-KIADADAD 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111363 515 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCE 588
Cdd:COG3883 134 LLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAA 207
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
198-478 |
8.29e-05 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 46.77 E-value: 8.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 198 DDFTNLLEQE---RERLKKLLEQ----EKAYQARKEK-ENA-----KRLNKLRDELVKLKSF--------ALMLVDERQM 256
Cdd:pfam06160 107 EELDELLESEeknREEVEELKDKyrelRKTLLANRFSyGPAideleKQLAEIEEEFSQFEELtesgdyleAREVLEKLEE 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 257 HIEQLGLQSQKV----QDLTQKLREEEEKLKAiTYkskedrQKLLKLEVDFEHKAsrFSQEHEEMNAKLANQESHNRQLR 332
Cdd:pfam06160 187 ETDALEELMEDIpplyEELKTELPDQLEELKE-GY------REMEEEGYALEHLN--VDKEIQQLEEQLEENLALLENLE 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 333 LK-----LVGLSQRIEEL----EETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKR-------VLEMEGKDEE 396
Cdd:pfam06160 258 LDeaeeaLEEIEERIDQLydllEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSytlneneLERVRGLEKQ 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 397 ITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSectqlhlNLEKEKNLTKDLLNELEVVKSR 476
Cdd:pfam06160 338 LEELEKRYDEIVERLEEKEVAYSELQEELEEILEQLEEIEEEQEEFKESLQ-------SLRKDELEAREKLDEFKLELRE 410
|
..
gi 1270111363 477 VK 478
Cdd:pfam06160 411 IK 412
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
265-481 |
1.01e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.55 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 265 SQKVQDLTQKLREEEEKLKAitYKSKEDrqkllklEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEE 344
Cdd:COG3206 181 EEQLPELRKELEEAEAALEE--FRQKNG-------LVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 345 LEETNKSLQkAEEELQELRDKIAKgecgnssLMAEVESLRKRVLE----MEGKDEEITKTEAQCR-ELKKKLQEEEHHSK 419
Cdd:COG3206 252 GPDALPELL-QSPVIQQLRAQLAE-------LEAELAELSARYTPnhpdVIALRAQIAALRAQLQqEAQRILASLEAELE 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 420 ELRLEVEKLQKRMSELEKLEEAFSRSKSEctqlHLNLEKEKNLTKDLLNELEvvkSRVKELE 481
Cdd:COG3206 324 ALQAREASLQAQLAQLEARLAELPELEAE----LRRLEREVEVARELYESLL---QRLEEAR 378
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
545-787 |
1.12e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.67 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 545 EKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINrgrlckgseftcp 624
Cdd:COG1340 18 EELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELN------------- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 625 edNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQ----------DKANFLSQQLEEIKHQMAKNKAI 694
Cdd:COG1340 85 --EKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKALEKNEKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 695 EkgEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLS----QLQVDYSVLQQRFMEEETKNKNMGREVL 770
Cdd:COG1340 163 K--ELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRkeadELHKEIVEAQEKADELHEEIIELQKELR 240
|
250
....*....|....*..
gi 1270111363 771 NLTKELELSKRYSRALR 787
Cdd:COG1340 241 ELRKELKKLRKKQRALK 257
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
351-741 |
1.14e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 351 SLQKAEEELQELrDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEitKTEAQCRELKKKLQEEEHHS--KELRLEVEKL 428
Cdd:pfam12128 170 ALCDSESPLRHI-DKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPP--KSRLNRQQVEHWIRDIQAIAgiMKIRPEFTKL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 429 QKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVvKSRVKELECSESRLE-KVELSLKDDLTKLKSFTVM 507
Cdd:pfam12128 247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQ-LLRTLDDQWKEKRDElNGELSAADAAVAKDRSELE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 508 LVDERKNMMEKIKQEERKVD------------GLNKNFKVEQGKVMDVTEKLieeSKKLLKLKSEMEEKVYSLTKERDel 575
Cdd:pfam12128 326 ALEDQHGAFLDADIETAAADqeqlpswqseleNLEERLKALTGKHQDVTAKY---NRRRSKIKEQNNRDIAGIKDKLA-- 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 576 mgKLRSEEERSCELSCSVdllkkrLDGIEEVEREinrgrlckgseftcPEDNKIRELTLEIERLKKRLQQLEVVEGDLMK 655
Cdd:pfam12128 401 --KIREARDRQLAVAEDD------LQALESELRE--------------QLEAGKLEFNEEEYRLKSRLGELKLRLNQATA 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 656 TEDEYDQLEQ------KFRTEQDKAN--FLSQQLEEIKHQMAKNKAIEKGEAVSQeaelrhrfRMEEAKSRDLQAEVQ-- 725
Cdd:pfam12128 459 TPELLLQLENfderieRAREEQEAANaeVERLQSELRQARKRRDQASEALRQASR--------RLEERQSALDELELQlf 530
|
410
....*....|....*.
gi 1270111363 726 ALKEKIHELMNKEDQL 741
Cdd:pfam12128 531 PQAGTLLHFLRKEAPD 546
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
220-633 |
1.24e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 46.21 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 220 AYQARKEKENAKRLNKLRDELvklksfalmlvderQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKS--KEDRQKLL 297
Cdd:pfam13166 85 FTLGEESIEIQEKIAKLKKEI--------------KDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKikRKKNSALS 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 298 KLEVDFEHKASRFSQEHEEMNAKLANQEShnrqlRLKLVGLSQRIEELEETNK-SLQKAEEELQELRDKIAKGECGNS-- 374
Cdd:pfam13166 151 EALNGFKYEANFKSRLLREIEKDNFNAGV-----LLSDEDRKAALATVFSDNKpEIAPLTFNVIDFDALEKAEILIQKvi 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 375 SLMAEVESLRKR------VLEMEGKDEEITKTEAQC-----RELKKKLqeEEHHSKELRLEVEKLQKRMSELEKLEEAFS 443
Cdd:pfam13166 226 GKSSAIEELIKNpdladwVEQGLELHKAHLDTCPFCgqplpAERKAAL--EAHFDDEFTEFQNRLQKLIEKVESAISSLL 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 444 RSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLE--KVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 521
Cdd:pfam13166 304 AQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLDGL---RRALEakRKDPFKSIELDSVDAKIESINDLVASINELIAK 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 522 EERKVDGLNKnfKVEQGKV---MDVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERSCELScsvDLLKK 598
Cdd:pfam13166 381 HNEITDNFEE--EKNKAKKklrLHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELE---AQLRD 455
|
410 420 430
....*....|....*....|....*....|....*...
gi 1270111363 599 RLDGIEEVEREINR---GRLckgsEFTCPEDNKIRELT 633
Cdd:pfam13166 456 HKPGADEINKLLKAfgfGEL----ELSFNEEGKGYRII 489
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
379-596 |
1.26e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 46.07 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 379 EVESLRKrvlemEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSEctqlHLNLEK 458
Cdd:PRK05771 32 HIEDLKE-----ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKV--SVKSLEELIKDVEEE----LEKIEK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 459 EknlTKDLLNELEVVKSRVKELECSESRLEK-----VELSLKDDLTKLKSFTVML----VDERKNMMEKIKQEERKVDGL 529
Cdd:PRK05771 101 E---IKELEEEISELENEIKELEQEIERLEPwgnfdLDLSLLLGFKYVSVFVGTVpedkLEELKLESDVENVEYISTDKG 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1270111363 530 N--------KNFKVEQGKVM---DVTEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRS-EEERSCELSCSVDLL 596
Cdd:PRK05771 178 YvyvvvvvlKELSDEVEEELkklGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKElAKKYLEELLALYEYL 256
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
204-612 |
1.42e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 204 LEQERERLKKLLEQEKAYQARKEkENAKRLNKLRDELVKLKSF--ALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEK 281
Cdd:COG4717 83 AEEKEEEYAELQEELEELEEELE-ELEAELEELREELEKLEKLlqLLPLYQELEALEAELAELPERLEELEERLEELREL 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 282 LKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKaEEELQE 361
Cdd:COG4717 162 EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN-ELEAAA 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 362 LRDKIAKGE---------CGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRm 432
Cdd:COG4717 241 LEERLKEARlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE- 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 433 sELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEvvkSRVKELECSESRLEKVELSLKDDLTKLKSFT--VMLVD 510
Cdd:COG4717 320 -ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE---ELEEELQLEELEQEIAALLAEAGVEDEEELRaaLEQAE 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 511 ERKNMMEKIKQEERKVDGLNKNFKVEQGkvmDVTEKLIEEskKLLKLKSEMEEkvysLTKERDELMGKLRSEEERSCELS 590
Cdd:COG4717 396 EYQELKEELEELEEQLEELLGELEELLE---ALDEEELEE--ELEELEEELEE----LEEELEELREELAELEAELEQLE 466
|
410 420
....*....|....*....|..
gi 1270111363 591 CSVDLLKKRLDgIEEVEREINR 612
Cdd:COG4717 467 EDGELAELLQE-LEELKAELRE 487
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
155-481 |
1.73e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 155 EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYmNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENA--KR 232
Cdd:COG4717 93 LQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY-QELEALEAELAELPERLEELEERLEELRELEEELEEleAE 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 233 LNKLRDELV-KLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYK---------SKEDRQKLLKLEVD 302
Cdd:COG4717 172 LAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqleneleAAALEERLKEARLL 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 303 F-----------------------------------------EHKASRFSQEHEEMNAKLANQESHNRQLR--LKLVGLS 339
Cdd:COG4717 252 LliaaallallglggsllsliltiagvlflvlgllallflllAREKASLGKEAEELQALPALEELEEEELEelLAALGLP 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 340 ------------QRIEELEETNKSLQKAEEELQ--ELRDKIAK--GECGNSSLmAEVESLRKRVLEMEGKDEEITKTEAQ 403
Cdd:COG4717 332 pdlspeellellDRIEELQELLREAEELEEELQleELEQEIAAllAEAGVEDE-EELRAALEQAEEYQELKEELEELEEQ 410
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 404 CRELKKKLQE--EEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTkDLLNELEVVKSRVKELE 481
Cdd:COG4717 411 LEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA-ELLQELEELKAELRELA 489
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
342-589 |
2.80e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 44.42 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 342 IEELEETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgKDEEITKTEAQCRELKKKLQEEEHHSKEL 421
Cdd:pfam15905 86 VQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELT-RVNELLKAKFSEDGTQKKMSSLSMELMKL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 422 RLEVEKLQKRMS--------ELEKLEEAFSRSKSECTQLH---LNLEKEKNLTKDLLNELEvvkSRVKELECSESRLEKV 490
Cdd:pfam15905 165 RNKLEAKMKEVMakqegmegKLQVTQKNLEHSKGKVAQLEeklVSTEKEKIEEKSETEKLL---EYITELSCVSEQVEKY 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 491 ELslkdDLTKLKSftvmLVDERKNMMEKIKQE-ERKVDGLNKnfkveQGKVMDVTEKLIEESKKllKLKSEMEEKVYSLT 569
Cdd:pfam15905 242 KL----DIAQLEE----LLKEKNDEIESLKQSlEEKEQELSK-----QIKDLNEKCKLLESEKE--ELLREYEEKEQTLN 306
|
250 260
....*....|....*....|
gi 1270111363 570 KERDELMGKLRSEEERSCEL 589
Cdd:pfam15905 307 AELEELKEKLTLEEQEHQKL 326
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
378-525 |
2.89e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.77 E-value: 2.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 378 AEVESLRKRVLeMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLE 457
Cdd:PRK12704 49 KEAEAIKKEAL-LEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELE 127
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111363 458 KEKNLTKDLLNELEVVKSRVKELECSESR---LEKVELSLKDDLTKLKsftvmlvderKNMMEKIKQEERK 525
Cdd:PRK12704 128 KKEEELEELIEEQLQELERISGLTAEEAKeilLEKVEEEARHEAAVLI----------KEIEEEAKEEADK 188
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
955-1168 |
3.32e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 44.92 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 955 IPSPNVMSQKPKSAD-------------PTLGPERAMSPVTITTISREKSPeggRGAFAD--RPASPIQIMTVSTSAAPP 1019
Cdd:PLN03209 323 IPSQRVPPKESDAADgpkpvptkpvtpeAPSPPIEEEPPQPKAVVPRPLSP---YTAYEDlkPPTSPIPTPPSSSPASSK 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 1020 EI-AVS-PDSQEVPMGRTILKVTPEKQTVPTPMRKYNANANIITTEDNKIhihlgsqfKRSPGPAAAEGVSPVITVRPVn 1097
Cdd:PLN03209 400 SVdAVAkPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKP--------PTSPSPTAPTGVSPSVSSTSS- 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 1098 VTAEKEVSTGTV-----------------------LRSPRNHLSSRPGANKVTSTITITPVTTSSTRGTQSVSGQDGSSQ 1154
Cdd:PLN03209 471 VPAVPDTAPATAatdaaapppanmrplspyavyddLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQP 550
|
250
....*....|....*
gi 1270111363 1155 RPTP-TRIPMSKGMK 1168
Cdd:PLN03209 551 KPRPlSPYTMYEDLK 565
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
400-728 |
3.67e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 44.71 E-value: 3.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 400 TEAQCRELKKKLQEEehhskelRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVV------ 473
Cdd:pfam05483 97 IEAELKQKENKLQEN-------RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETcarsae 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 474 KSRVKELECSESRLEKVEL--SLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGK--------VMDV 543
Cdd:pfam05483 170 KTKKYEYEREETRQVYMDLnnNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDkekqvsllLIQI 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 544 TEK---------LIEESK-------KLLKLKSE----MEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGI 603
Cdd:pfam05483 250 TEKenkmkdltfLLEESRdkanqleEKTKLQDEnlkeLIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQL 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 604 EEVE----REINRGRLCKG---SEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 676
Cdd:pfam05483 330 TEEKeaqmEELNKAKAAHSfvvTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEE 409
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1270111363 677 LSQQLEEIKHQMAKNKAIEK--GEAVSQEAELRHRFRMEEAKSRDLQAEVQALK 728
Cdd:pfam05483 410 LKKILAEDEKLLDEKKQFEKiaEELKGKEQELIFLLQAREKEIHDLEIQLTAIK 463
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
259-500 |
4.07e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 4.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 259 EQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN-------QESHNRQL 331
Cdd:PHA02562 181 QQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNlvmdiedPSAALNKL 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 332 RLKLVGLSQRIEELEETNKSLQKAEE------ELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCR 405
Cdd:PHA02562 261 NTAAAKIKSKIEQFQKVIKMYEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 406 ELKKKLqeeEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNltkdllnelevvksrvkelECSES 485
Cdd:PHA02562 341 ELKNKI---STNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK-------------------TKSEL 398
|
250
....*....|....*
gi 1270111363 486 RLEKVELSLKDDLTK 500
Cdd:PHA02562 399 VKEKYHRGIVTDLLK 413
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
204-412 |
4.80e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 204 LEQERERLKKLLEQ-EKAYQARKEKEN-----------AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDL 271
Cdd:COG3206 180 LEEQLPELRKELEEaEAALEEFRQKNGlvdlseeakllLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 272 TQKLREEEeklkaitykskeDRQKLLKLEVDFEHKASRFSQEHEEMnaklanqeshnRQLRLKLVGLSQRIEEleETNKS 351
Cdd:COG3206 260 LQSPVIQQ------------LRAQLAELEAELAELSARYTPNHPDV-----------IALRAQIAALRAQLQQ--EAQRI 314
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111363 352 LQKAEEELQELRdkiakgecgnsslmAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQ 412
Cdd:COG3206 315 LASLEAELEALQ--------------AREASLQAQLAQLEARLAELPELEAELRRLEREVE 361
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
408-616 |
5.95e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.12 E-value: 5.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 408 KKKLQEEEHHSKELRlEVEKLQKRMSELE-KLEEAFSRSK---SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 483
Cdd:PLN02939 149 QARLQALEDLEKILT-EKEALQGKINILEmRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKE 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 484 ESRLEKVELSLKDDLTKLKSftvmlvderknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 563
Cdd:PLN02939 228 LDVLKEENMLLKDDIQFLKA-----------ELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYD 296
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1270111363 564 KVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRLC 616
Cdd:PLN02939 297 CWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSKFS 349
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
70-414 |
7.23e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.18 E-value: 7.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 70 KKPLELSKEDLIQL----------LSIMEGELQA--------REDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDA 131
Cdd:PRK04863 299 RRQLAAEQYRLVEMarelaelneaESDLEQDYQAasdhlnlvQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQ 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 132 ILAQEK-SIGEDVYEKPISEL----DRLEEKQKET--YRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLL 204
Cdd:PRK04863 379 EENEARaEAAEEEVDELKSQLadyqQALDVQQTRAiqYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEL 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 205 EQERERL---KKLLEQ-EKAYQA-RK-----EKENAKrlNKLRDELVKLKSFalmlvderQMHIEQLGLQSQKVQDLTQK 274
Cdd:PRK04863 459 LSLEQKLsvaQAAHSQfEQAYQLvRKiagevSRSEAW--DVARELLRRLREQ--------RHLAEQLQQLRMRLSELEQR 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 275 LREEEEKLKAITYKSKEDRQKLLKlEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQK 354
Cdd:PRK04863 529 LRQQQRAERLLAEFCKRLGKNLDD-EDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLA 607
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 355 AEEELQELRDKIakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEE 414
Cdd:PRK04863 608 AQDALARLREQS--GEEFEDS--QDVTEYMQQLLERE---RELTVERDELAARKQALDEE 660
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
340-876 |
7.74e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.88 E-value: 7.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 340 QRIEELEETNKSLQKAEEELQELRDKI----AKGECGNS---SLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQ 412
Cdd:TIGR00606 200 QKVQEHQMELKYLKQYKEKACEIRDQItskeAQLESSREivkSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 413 EEEHHSKELRLEVEKL----QKRMSELEKLEEAFSRSKSE----CTQLHLNLEKEKNLTKDLLNELEVVKSRVK---ELE 481
Cdd:TIGR00606 280 QMEKDNSELELKMEKVfqgtDEQLNDLYHNHQRTVREKERelvdCQRELEKLNKERRLLNQEKTELLVEQGRLQlqaDRH 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 482 CSESR---LEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 558
Cdd:TIGR00606 360 QEHIRardSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLG 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 559 SEMEEKVYSLTKERDELMGKLRSEEErsceLSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTCPEDNKIRELTLEIER 638
Cdd:TIGR00606 440 RTIELKKEILEKKQEELKFVIKELQQ----LEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDR 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 639 LKKRLQQ--------LEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKAIEKgeavsqeaeLRHRF 710
Cdd:TIGR00606 516 KLRKLDQemeqlnhhTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHS---------KSKEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 711 RMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSvlQQRF-----MEEETKNKNMGREVLNLTKELEL----SKR 781
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE--DKLFdvcgsQDEESDLERLKEEIEKSSKQRAMlagaTAV 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 782 YSRALRPSGNGRRMVdVPVASTGVQTEAVCGDAAEEETPAVFIRKSFQEEnhimsnLRQVGLKKPMERSSVLDRYPPAAN 861
Cdd:TIGR00606 665 YSQFITQLTDENQSC-CPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKS------TESELKKKEKRRDEMLGLAPGRQS 737
|
570
....*....|....*
gi 1270111363 862 ELTMRKSWIPWMRKR 876
Cdd:TIGR00606 738 IIDLKEKEIPELRNK 752
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
45-428 |
8.14e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 8.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 45 GEDDVMASGTVKRHLKPSGESEKKTKKPLELSKEDLIQLLSIMEGELQAREDVIHMLktekTKPEVLEAHYGSAEPEKVL 124
Cdd:TIGR00618 533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL----QNITVRLQDLTEKLSEAED 608
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 125 RVLHRDAILAQEKSIGEDVYEKpiseldRLEEKQKETYrrmlEQLLLAEKchrrTVYELENEKHKHTDYMNKSDDFTNLL 204
Cdd:TIGR00618 609 MLACEQHALLRKLQPEQDLQDV------RLHLQQCSQE----LALKLTAL----HALQLTLTQERVREHALSIRVLPKEL 674
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 205 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFalmlvdERQMHIEQLGLQSQKvqdltQKLREEEEKLKA 284
Cdd:TIGR00618 675 LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEY------DREFNEIENASSSLG-----SDLAAREDALNQ 743
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 285 ITYKSKEDRQKLLKLEVDFEHKASrfsqEHEEMNAKLANQESHNRQlrlklvGLSQRIEELEETNKSLQKAEEEL-QELR 363
Cdd:TIGR00618 744 SLKELMHQARTVLKARTEAHFNNN----EEVTAALQTGAELSHLAA------EIQFFNRLREEDTHLLKTLEAEIgQEIP 813
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111363 364 DKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL 428
Cdd:TIGR00618 814 SDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
337-505 |
8.30e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 43.08 E-value: 8.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 337 GLSQRIEELEETNKSLQKAEEELQELRDKIAKGecgNSSLMAEVESLRKRVLEMEGKDEEITKteaqcrELKKKLQEEEH 416
Cdd:smart00787 148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDR---KDALEEELRQLKQLEDELEDCDPTELD------RAKEKLKKLLQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 417 HSKELRLEVEKLQKRMSELEKleeafsrsksectqlhlNLEKEKNLTKDLLNELEVVKSRVKelECSESRLEKVELsLKD 496
Cdd:smart00787 219 EIMIKVKKLEELEEELQELES-----------------KIEDLTNKKSELNTEIAEAEKKLE--QCRGFTFKEIEK-LKE 278
|
....*....
gi 1270111363 497 DLTKLKSFT 505
Cdd:smart00787 279 QLKLLQSLT 287
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
459-787 |
8.84e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.77 E-value: 8.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 459 EKNLT--KDLLNELEvvkSRVKELEcSESRLEKVELSLKDDLTKLKSFtvMLVDERKNMMEKIKQEERKVDGLNKNFkve 536
Cdd:COG1196 185 EENLErlEDILGELE---RQLEPLE-RQAEKAERYRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAEL--- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 537 qgkvmdvtEKLIEESKKLLKLKSEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRgrlc 616
Cdd:COG1196 256 --------EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE-----------------LARLEQDIAR---- 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 617 kgseftcpEDNKIRELTLEIERLKKRL-----------QQLEVVEGDLMKTEDEYDQLEQKFRTEQDK-ANFLSQQLEEI 684
Cdd:COG1196 307 --------LEERRRELEERLEELEEELaeleeeleeleEELEELEEELEEAEEELEEAEAELAEAEEAlLEAEAELAEAE 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 685 KHQMAKNKAI-----EKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDysvLQQRFMEEE 759
Cdd:COG1196 379 EELEELAEELlealrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE---AAEEEAELE 455
|
330 340
....*....|....*....|....*...
gi 1270111363 760 TKNKNMGREVLNLTKELELSKRYSRALR 787
Cdd:COG1196 456 EEEEALLELLAELLEEAALLEAALAELL 483
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
535-787 |
8.93e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 8.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 535 VEQGKVMDVTE-------KLIEESKKLLKLKsemeekvysltKERDELMGKLRSEEErscelscsvDLlkKRLDGI-EEV 606
Cdd:TIGR02168 141 IEQGKISEIIEakpeerrAIFEEAAGISKYK-----------ERRKETERKLERTRE---------NL--DRLEDIlNEL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 607 EREINRgrLCKGSEFTcpedNKIRELTLEIERLKKRLQ--QLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI 684
Cdd:TIGR02168 199 ERQLKS--LERQAEKA----ERYKELKAELRELELALLvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLEEL 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 685 KHQMAK-------------NKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNK----EDQLSQLQVD 747
Cdd:TIGR02168 273 RLEVSEleeeieelqkelyALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEElaelEEKLEELKEE 352
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1270111363 748 YSVLQQRFMEEETKNKNMGREVLNLTKELE-LSKRYSRALR 787
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEELEEQLEtLRSKVAQLEL 393
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
405-682 |
9.27e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.38 E-value: 9.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 405 RELKKKLQEEEHHskELRLEVEKLQKRMSELEKLEEAFSRSKSEctQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Cdd:PRK05771 34 EDLKEELSNERLR--KLRSLLTKLSEALDKLRSYLPKLNPLREE--KKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 485 SRLE---KVELSLKDDLTKLKSFTVMLVDERKNmmekikqeerkvdglnKNFKVEQGKV-MDVTE--KLIEESKKLLKLK 558
Cdd:PRK05771 110 SELEneiKELEQEIERLEPWGNFDLDLSLLLGF----------------KYVSVFVGTVpEDKLEelKLESDVENVEYIS 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 559 SEMEEKVYSLTKERdELMGKLRSEEERscelscsVDLLKKRLDGIEEVEREINRgrlckgseftcpEDNKIRELTLEIER 638
Cdd:PRK05771 174 TDKGYVYVVVVVLK-ELSDEVEEELKK-------LGFERLELEEEGTPSELIRE------------IKEELEEIEKERES 233
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1270111363 639 LKKRLQQLEVVEGDLMKTEDEYdqLEQkfrtEQDKANFLSQQLE 682
Cdd:PRK05771 234 LLEELKELAKKYLEELLALYEY--LEI----ELERAEALSKFLK 271
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
378-786 |
1.04e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 43.63 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 378 AEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRM-SELEKLEEAFsrsksecTQLHLNL 456
Cdd:pfam01576 12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLaARKQELEEIL-------HELESRL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 457 EKEKNLTKDLLNELEVVKSRVKELecsESRLEKVElslkDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVE 536
Cdd:pfam01576 85 EEEEERSQQLQNEKKKMQQHIQDL---EEQLDEEE----AARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 537 QGKVMDVTEKLIEE---SKKLLKLKSEMEEKVysltkerDELMGKLRSEEERSCELscsvDLLKKRLDGieevereinrg 613
Cdd:pfam01576 158 EERISEFTSNLAEEeekAKSLSKLKNKHEAMI-------SDLEERLKKEEKGRQEL----EKAKRKLEG----------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 614 rlckgseftcpEDNKIRELTLEIErlkkrlQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAknka 693
Cdd:pfam01576 216 -----------ESTDLQEQIAELQ------AQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQIS---- 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 694 iEKGEAVSQEAELRHRfrmEEAKSRDLQAEVQALKEKIHELMN----KEDQLSQLQVDYSVLqQRFMEEETKN------- 762
Cdd:pfam01576 275 -ELQEDLESERAARNK---AEKQRRDLGEELEALKTELEDTLDttaaQQELRSKREQEVTEL-KKALEEETRSheaqlqe 349
|
410 420
....*....|....*....|....*.
gi 1270111363 763 --KNMGREVLNLTKELELSKRYSRAL 786
Cdd:pfam01576 350 mrQKHTQALEELTEQLEQAKRNKANL 375
|
|
| DYN1 |
COG5245 |
Dynein, heavy chain [Cytoskeleton]; |
156-668 |
1.10e-03 |
|
Dynein, heavy chain [Cytoskeleton];
Pssm-ID: 227570 [Multi-domain] Cd Length: 3164 Bit Score: 43.44 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 156 EKQKETYRRMLEqllLAEKCHRRTVYELENEKHKhtdymNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNK 235
Cdd:COG5245 2102 RKYNEYGRGMGE---LKEQLSNTVVILGVKEKNA-----DDALSGTPGERLEREVKSVFVEAPRDMLFLLEEEVRKRKGS 2173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 236 LRdelvKLKSFALMLVDERQMHIEQL-GLQSQKVQDLTQK---LREEEEKLKAITY---KSKEDRQKLLK---------- 298
Cdd:COG5245 2174 VM----KFKSSKKPAVLEAVLFVYKIkKASLREIRSFIRPpgdLCIEMEDVCDLLGfeaKIWFGEQQSLRrddfiriigk 2249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 299 --LEVDFEHKASRFsQEHEEMNAKLANQESHNRQLRL---------KLVGLSQRIEELEETNKSLQKAEEELQELRDKIA 367
Cdd:COG5245 2250 ypDEIEFDLEARRF-REARECSDPSFTGSILNRASKAcgplkrwlvRECNRSKVLEVKIPLREEEKRIDGEAFLVEDRLT 2328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 368 KGECGNSSLMAEVESLRKR----VLEMEGKdeeitktEAQCRELKKKLQEEEHHSKELRLEVEK-------LQKRMSELe 436
Cdd:COG5245 2329 LGKGLSSDLMTFKLRRRSYysldILRVHGK-------IADMDTVHKDVLRSIFVSEILINEDSEwggvfseVPKLMVEL- 2400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 437 kLEEAFSRSKSECTQLHLN-LEK--EKNLTKDLL-NELEVVKSRVKEL--ECSESRLEKVELSLKDDLT--------KLK 502
Cdd:COG5245 2401 -DGDGHPSSCLHPYIGTLGfLCRaiEFGMSFIRIsKEFRDKEIRRRQFitEGVQKIEDFKEEACSTDYGlensrirkDLQ 2479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 503 SFTVMLVDERKNMMEKIKQ--EERKVDGLNKNFKVEQ-----------GKVMDVTEKLIEESKKLLKLKS---------- 559
Cdd:COG5245 2480 DLTAVLNDPSSKIVTSQRQmyDEKKAILGSFREMEFAfglsqarregsDKIIGDAEALDEEIGRLIKEEFksnlsevkvm 2559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 560 --------EMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKKR-LDGIEEV--------EREINRGRLCKGSEFT 622
Cdd:COG5245 2560 inppeivrSTVEAVFWLSEGRSGDMGSIEWKQLIQVMFVSKVLGCETEiPDALEKLvsgplfvhEKALNALKACGSLFLW 2639
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 1270111363 623 CPEDNKIRELTLEIE-------------RLKKRLQQLEVVEGDLMKTEDEYDQLEQKFR 668
Cdd:COG5245 2640 VLARYLLAKLMLSISnmeqtdeiavllhNLKKSRKEIEEEESESMEIEDRIDALKSEYN 2698
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
206-445 |
1.19e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.09 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 206 QERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfaLMLVDERQMHIEQLGLQSQ--KVQDLT-QKLREEEEKL 282
Cdd:pfam05667 243 RKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAEL----LSSFSGSSTTDTGLTKGSRftHTEKLQfTNEAPAATSS 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 283 KAITYKSKEDRQKLLKLEVD-FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQE 361
Cdd:pfam05667 319 PPTKVETEEELQQQREEELEeLQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPD 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 362 LRDKIAKgecgnssLMAEVESLRKRVLEMEGKDEEIT----------KTEAQCREL--KKKLQE-EEHHSK------ELR 422
Cdd:pfam05667 399 AEENIAK-------LQALVDASAQRLVELAGQWEKHRvplieeyralKEAKSNKEDesQRKLEEiKELREKikevaeEAK 471
|
250 260
....*....|....*....|...
gi 1270111363 423 LEVEKLQKRMSELEKLEEAFSRS 445
Cdd:pfam05667 472 QKEELYKQLVAEYERLPKDVSRS 494
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
401-689 |
1.48e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 401 EAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEE-AFSRSKSECTQLHL-NLEKEKNLTKDLLNELEVVKSRVK 478
Cdd:COG4913 616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEySWDEIDVASAEREIaELEAELERLDASSDDLAALEEQLE 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 479 ELECSESRLEKVELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLNKNFKVEQgkvmdvtEKLIEESKKLLKLK 558
Cdd:COG4913 696 ELEAELEELEEELDELKGEIGRLEK-------ELEQAEEELDELQDRLEAAEDLARLEL-------RALLEERFAAALGD 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 559 SEMEEKVYSLTKERDELMGKLRSEEERscelscsvdllkkrldgIEEVEREINRgrlckgsEFTCPednkIRELTLEIER 638
Cdd:COG4913 762 AVERELRENLEERIDALRARLNRAEEE-----------------LERAMRAFNR-------EWPAE----TADLDADLES 813
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111363 639 L---KKRLQQLEvvEGDLMKTEDEYDQLEQKFrTEQDKANFLS---QQLEEIKHQMA 689
Cdd:COG4913 814 LpeyLALLDRLE--EDGLPEYEERFKELLNEN-SIEFVADLLSklrRAIREIKERID 867
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
230-735 |
1.60e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.64 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 230 AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEHKASR 309
Cdd:COG5185 106 LIKLPNYEWSADILISLLYLYKSEIVALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFGLT 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 310 FSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIAKGEcgnssLMAEVESLRKRVLE 389
Cdd:COG5185 186 LGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELE-----DLAQTSDKLEKLVE 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 390 megKDEEI-TKTEAQCRELKKKLQEEehhSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHlNLEKEKNLTKDLLN 468
Cdd:COG5185 261 ---QNTDLrLEKLGENAESSKRLNEN---ANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA-AAEAEQELEESKRE 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 469 ELEVVKSRVKELECSESRLEKVELSLKDDLTKLksFTVMLVDERKNMMEKIKQEerkvdgLNKNFKVEQGKVMDVTEKLI 548
Cdd:COG5185 334 TETGIQNLTAEIEQGQESLTENLEAIKEEIENI--VGEVELSKSSEELDSFKDT------IESTKESLDEIPQNQRGYAQ 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 549 EESKKLLKLKSEMEEkvysltkERDELMGKLRSEEErscELSCSVDLLKKRLDGIEEVEREINRGRLCKGSEFTcpeDNK 628
Cdd:COG5185 406 EILATLEDTLKAADR-------QIEELQRQIEQATS---SNEEVSKLLNELISELNKVMREADEESQSRLEEAY---DEI 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 629 IRELTLEIERLKKRLQQLE---------------VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKNKA 693
Cdd:COG5185 473 NRSVRSKKEDLNEELTQIEsrvstlkatleklraKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQ 552
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1270111363 694 IEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELM 735
Cdd:COG5185 553 ASNAKTDGQAANLRTAVIDELTQYLSTIESQQAREDPIPDQA 594
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
226-524 |
1.82e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 41.82 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 226 EKENAKRLNKLRDELVKLKsfalmlvDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLEVDFEH 305
Cdd:COG1340 10 LEELEEKIEELREEIEELK-------EKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 306 KASRFSQEHEEMNaKLANQESHNRQLRLKLVGLSQRIEELEET--NKSLQKAEEelQELRDKIAkgecgnsslmaEVESL 383
Cdd:COG1340 83 LNEKLNELREELD-ELRKELAELNKAGGSIDKLRKEIERLEWRqqTEVLSPEEE--KELVEKIK-----------ELEKE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 384 RKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEafsrSKSECTQLHLNLEKEKNL 462
Cdd:COG1340 149 LEKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELyKEADE----LRKEADELHKEIVEAQEK 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111363 463 TKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFtvmlvDERKNMMEKIKQEER 524
Cdd:COG1340 225 ADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEELE-----EKAEEIFEKLKKGEK 281
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
334-588 |
1.87e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.42 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 334 KLVGLSQRIEELE--ETNKSLQKAEEELQEL--RDKIAKGECGNSSLM---AEVESLRKRVLEMEGKDEEITKTEAQCRE 406
Cdd:pfam17380 282 KAVSERQQQEKFEkmEQERLRQEKEEKAREVerRRKLEEAEKARQAEMdrqAAIYAEQERMAMERERELERIRQEERKRE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 407 LKKKLQEE-----EHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELE 481
Cdd:pfam17380 362 LERIRQEEiameiSRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 482 CSESR-LEKVELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE 560
Cdd:pfam17380 442 EERAReMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKE 521
|
250 260
....*....|....*....|....*...
gi 1270111363 561 MEEKVYSLTKERDelmgKLRSEEERSCE 588
Cdd:pfam17380 522 MEERQKAIYEEER----RREAEEERRKQ 545
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
381-742 |
1.90e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.19 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 381 ESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEK 460
Cdd:pfam07888 38 ECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 461 NLtkdLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSFTVMLV-------DERKNMMEKIKQEERKVDGLNKNF 533
Cdd:pfam07888 118 DA---LLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGaqrkeeeAERKQLQAKLQQTEEELRSLSKEF 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 534 KVEQGKvmdvtekLIEESKKLLKLKSEMEEKVYSLTK------ERDELMGKLRSEEERSCELSCSVDLLKKRLDGI---- 603
Cdd:pfam07888 195 QELRNS-------LAQRDTQVLQLQDTITTLTQKLTTahrkeaENEALLEELRSLQERLNASERKVEGLGEELSSMaaqr 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 604 EEVEREINRGRLcKGSEFTcpedNKIRELTLEIERLKKRLQQLEvvEGDLMKTEDEYDQLEQKFRTEQDKANFLSQ---Q 680
Cdd:pfam07888 268 DRTQAELHQARL-QAAQLT----LQLADASLALREGRARWAQER--ETLQQSAEADKDRIEKLSAELQRLEERLQEermE 340
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111363 681 LEEIKHQMAKNK---AIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLS 742
Cdd:pfam07888 341 REKLEVELGREKdcnRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVA 405
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
254-639 |
1.91e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.64 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 254 RQMHIEQLGLQsqkvqdltqklREEEEKLKAityKSKEDRQKLLKLEVDFehkaSRFSQEHEEMnAKLANQESHNRQLRL 333
Cdd:PRK04863 784 REKRIEQLRAE-----------REELAERYA---TLSFDVQKLQRLHQAF----SRFIGSHLAV-AFEADPEAELRQLNR 844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 334 KLVGLSQRIEELEETNKS----LQKAEEELQELRDKIakgecGNSSLMAEvESLRKRVLEMEgkdEEITKTE-------- 401
Cdd:PRK04863 845 RRVELERALADHESQEQQqrsqLEQAKEGLSALNRLL-----PRLNLLAD-ETLADRVEEIR---EQLDEAEeakrfvqq 915
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 402 --AQCRELKK---KLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRsksectQLHLNLEKEKN-LTKDllNEL- 470
Cdd:PRK04863 916 hgNALAQLEPivsVLQSDPEQFEQLKQDYQQAQQTQRDAKQqafaLTEVVQR------RAHFSYEDAAEmLAKN--SDLn 987
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 471 EVVKSRVKELECSESRLeKVELSLKDD--------LTKLKS-FTVM--LVDERKNMMEKI---------KQEERKVDGLN 530
Cdd:PRK04863 988 EKLRQRLEQAEQERTRA-REQLRQAQAqlaqynqvLASLKSsYDAKrqMLQELKQELQDLgvpadsgaeERARARRDELH 1066
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 531 KNFKVEQGKvmdvteklieeskkllklKSEMEEKVYSLTKERDELMGKLRSEEERSCELSCSVDLLKK------RLDGIE 604
Cdd:PRK04863 1067 ARLSANRSR------------------RNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAgwcavlRLVKDN 1128
|
410 420 430
....*....|....*....|....*....|....*
gi 1270111363 605 EVEREINRGRLckgSEFTCPEDNKIRELTLEIERL 639
Cdd:PRK04863 1129 GVERRLHRREL---AYLSADELRSMSDKALGALRL 1160
|
|
| ADIP |
pfam11559 |
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ... |
425-529 |
1.93e-03 |
|
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.
Pssm-ID: 463295 [Multi-domain] Cd Length: 151 Bit Score: 39.99 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 425 VEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKVELSLKDDLTKLKSf 504
Cdd:pfam11559 44 LQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKTQLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKN- 122
|
90 100
....*....|....*....|....*
gi 1270111363 505 tvMLVDERKNMMEKIKQEERKVDGL 529
Cdd:pfam11559 123 --ALQQIKTQFAHEVKKRDREIEKL 145
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
338-481 |
2.03e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.88 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 338 LSQRI----EELEETNKslqkaeeELQELRDKIAKGECGNSSLMAEVESLRKRVLEME-----------GKDEEITKTEA 402
Cdd:PRK09039 44 LSREIsgkdSALDRLNS-------QIAELADLLSLERQGNQDLQDSVANLRASLSAAEaersrlqallaELAGAGAAAEG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 403 QCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSRSKSEctqlhlnlEKEKNLT-KDLLNELEV-VKSR 476
Cdd:PRK09039 117 RAGELAQELDSEKQVSARALAQVELLNQQIAALRRqlaaLEAALDASEKR--------DRESQAKiADLGRRLNVaLAQR 188
|
....*
gi 1270111363 477 VKELE 481
Cdd:PRK09039 189 VQELN 193
|
|
| HAP1_N |
pfam04849 |
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ... |
226-365 |
2.13e-03 |
|
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.
Pssm-ID: 461455 [Multi-domain] Cd Length: 309 Bit Score: 41.55 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 226 EKENakrlNKLRDELVKLKSFALMLVDERQMHI----EQLGLQSQKVQDLTQKL-REEEEKLKaitykSKEDRQKLLKLE 300
Cdd:pfam04849 177 EEEN----LKLRSEASHLKTETDTYEEKEQQLMsdcvEQLSEANQQMAELSEELaRKMEENLR-----QQEEITSLLAQI 247
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111363 301 VDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEEtnkSLQKAEEELQELRDK 365
Cdd:pfam04849 248 VDLQHKCKELGIENEELQQHLQASKEAQRQLTSELQELQDRYAECLG---MLHEAQEELKELRKK 309
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
594-780 |
3.25e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 594 DLLKKRLDG----IEEVEREINRgrLCKGSEFTCPEDNKIRELT-LEiERLKKRLQQLEVVEGDLmkteDEYDQLEQKFR 668
Cdd:PRK11281 83 EQLKQQLAQapakLRQAQAELEA--LKDDNDEETRETLSTLSLRqLE-SRLAQTLDQLQNAQNDL----AEYNSQLVSLQ 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 669 TEQDKA-NFLS---QQLEEIKHQMAKNKAIEKGEAVSQEAELrhrfrmeeaksrdlQAEVQALKEKIhELMNKE----DQ 740
Cdd:PRK11281 156 TQPERAqAALYansQRLQQIRNLLKGGKVGGKALRPSQRVLL--------------QAEQALLNAQN-DLQRKSlegnTQ 220
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1270111363 741 LS---QLQVDYSVLQQRFMEEETKNKnmgREVLNlTKELELSK 780
Cdd:PRK11281 221 LQdllQKQRDYLTARIQRLEHQLQLL---QEAIN-SKRLTLSE 259
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
628-785 |
3.79e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.90 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 628 KIRELTLEIERLKKRLQQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK--NKAIEKGEA-- 699
Cdd:COG4942 42 ELAALKKEEKALLKQLAALErriaALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllRALYRLGRQpp 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 700 ----VSQE--AELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLT 773
Cdd:COG4942 122 lallLSPEdfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL 201
|
170
....*....|..
gi 1270111363 774 KELELSKRYSRA 785
Cdd:COG4942 202 ARLEKELAELAA 213
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
206-743 |
4.40e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.35 E-value: 4.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 206 QERERLKKLLEQEKAYQARKEKENAK------RLNKLRDELVKLKSFALMLVDERQMHIEQL-------GLQSQKVQDLT 272
Cdd:pfam10174 216 HRRNQLQPDPAKTKALQTVIEMKDTKisslerNIRDLEDEVQMLKTNGLLHTEDREEEIKQMevykshsKFMKNKIDQLK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 273 QKLREEEEKLKAITYK-----------------------SKEDRQKLLKLEVD-----------FEHKASRFSQEHEEMN 318
Cdd:pfam10174 296 QELSKKESELLALQTKletltnqnsdckqhievlkesltAKEQRAAILQTEVDalrlrleekesFLNKKTKQLQDLTEEK 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 319 AKLANQESHNRQL----RLKLVGLSQRIEELEEtnkSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEGKD 394
Cdd:pfam10174 376 STLAGEIRDLKDMldvkERKINVLQKKIENLQE---QLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 395 EEItkTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVK 474
Cdd:pfam10174 453 ERL--KEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKK 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 475 SRVKELEcsesrlekvelslkddlTKLKSFTVMLVDERKN--MMEKIKQEERKVdglnKNFKVEQGKVMDVTEKLIE--- 549
Cdd:pfam10174 531 EECSKLE-----------------NQLKKAHNAEEAVRTNpeINDRIRLLEQEV----ARYKEESGKAQAEVERLLGilr 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 550 --ESKKLLKLK--SEMEEKVYSLTKERDELMGKLRSEEErscelscsvDLLKKRLDGIEEVEREinrgrlcKGSEFTCPE 625
Cdd:pfam10174 590 evENEKNDKDKkiAELESLTLRQMKEQNKKVANIKHGQQ---------EMKKKGAQLLEEARRR-------EDNLADNSQ 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 626 DNKIRELTLEIERLKkrlQQLEVVEGDLMKTED---EYDQLEQKFRTEQDKanflsqQLEEI--KHQMAKNKAIEKGEAV 700
Cdd:pfam10174 654 QLQLEELMGALEKTR---QELDATKARLSSTQQslaEKDGHLTNLRAERRK------QLEEIleMKQEALLAAISEKDAN 724
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 1270111363 701 SQEAELrhrfrmEEAKSRDLQAEVQALKEKIHELMNKEDQLSQ 743
Cdd:pfam10174 725 IALLEL------SSSKKKKTQEEVMALKREKDRLVHQLKQQTQ 761
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
485-748 |
4.44e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.07 E-value: 4.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 485 SRLEKVE-LSLKDD----LTKLKSFTVMLVDErknmmekIKQEErkvdglnKNFKVEqgkvmDVTEKLIEESKKLLKLKS 559
Cdd:PRK05771 4 VRMKKVLiVTLKSYkdevLEALHELGVVHIED-------LKEEL-------SNERLR-----KLRSLLTKLSEALDKLRS 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 560 EMEEKvySLTKERDELMGKLRSEEerscelscsvdLLKKRLDGIEEVEREINRgrlckgseftcpEDNKIRELTLEIERL 639
Cdd:PRK05771 65 YLPKL--NPLREEKKKVSVKSLEE-----------LIKDVEEELEKIEKEIKE------------LEEEISELENEIKEL 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 640 KKRLQQLEVVEG-DL-MKTEDEYDQLEQKF-RTEQDKANFLSQQLEEIKHQMAKNK--------AIEKGEAVSQEAELR- 707
Cdd:PRK05771 120 EQEIERLEPWGNfDLdLSLLLGFKYVSVFVgTVPEDKLEELKLESDVENVEYISTDkgyvyvvvVVLKELSDEVEEELKk 199
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 708 HRFR-------------MEEAKSR--DLQAEVQALKEKIHELMNKEDQLSQLQVDY 748
Cdd:PRK05771 200 LGFErleleeegtpselIREIKEEleEIEKERESLLEELKELAKKYLEELLALYEY 255
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
511-738 |
5.55e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.52 E-value: 5.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 511 ERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEM---EEKVYSLTKERDELMGKLRSEEERsc 587
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalEAELAELEKEIAELRAELEAQKEE-- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 588 elscsvdlLKKRLDGIEEVEREINRGRLCKGSEFTcpedNKIRELTLEIERLKKRLQQLEvvegDLMKTEDEYDQLEQKF 667
Cdd:COG4942 106 --------LAELLRALYRLGRQPPLALLLSPEDFL----DAVRRLQYLKYLAPARREQAE----ELRADLAELAALRAEL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111363 668 RTEQDKANFLSQQLEEIKHQMAKNKAiekgEAVSQEAELRHRFRMEEAKSRDLQAEVQALKEKIHELMNKE 738
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
253-414 |
5.59e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.09 E-value: 5.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 253 ERQMHIEQLGLQSQKVQDLTQKLREE---EEKLKAITYKSKEDRQKllklEVDFEHKASRFSQEHEEMNAKLANQESHNR 329
Cdd:COG3096 506 SQQALAQRLQQLRAQLAELEQRLRQQqnaERLLEEFCQRIGQQLDA----AEELEELLAELEAQLEELEEQAAEAVEQRS 581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 330 QLRLKLVGLSQRIEELEETNKSLQKAEEELQELRDKIakGECGNSSlmAEVESLRKRVLEMEgkdEEITKTEAQCRELKK 409
Cdd:COG3096 582 ELRQQLEQLRARIKELAARAPAWLAAQDALERLREQS--GEALADS--QEVTAAMQQLLERE---REATVERDELAARKQ 654
|
....*
gi 1270111363 410 KLQEE 414
Cdd:COG3096 655 ALESQ 659
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
233-765 |
6.37e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 6.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 233 LNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKedRQKLLKLEVdfEHKASRFSQ 312
Cdd:TIGR01612 673 IDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENK--KNELLDIIV--EIKKHIHGE 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 313 EHEEMNAKLANQESHNRQLrlklvglSQRIEELEETNKSLQKAEEELQELR----DKIAKGECGNSSLMAEVESLRKRVL 388
Cdd:TIGR01612 749 INKDLNKILEDFKNKEKEL-------SNKINDYAKEKDELNKYKSKISEIKnhynDQINIDNIKDEDAKQNYDKSKEYIK 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 389 EMEGKDEEITKTEAQCRELKKKLQEEEhhSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNL-EKEKNLTKDLL 467
Cdd:TIGR01612 822 TISIKEDEIFKIINEMKFMKDDFLNKV--DKFINFENNCKEKIDSEHEQFAELTNKIKAEISDDKLNDyEKKFNDSKSLI 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 468 NE---------------------LEVVKSRVKELECSESRLEKVELSLKDDLTKLKS-----------FTVMLVDeRKNM 515
Cdd:TIGR01612 900 NEinksieeeyqnintlkkvdeyIKICENTKESIEKFHNKQNILKEILNKNIDTIKEsnlieksykdkFDNTLID-KINE 978
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 516 MEKIKQE-------------------------ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYSLTK 570
Cdd:TIGR01612 979 LDKAFKDaslndyeaknnelikyfndlkanlgKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIID 1058
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 571 ERDELMGKlrseeerscelscSVDLLKKRLdgIEEVEREInrgrlckgSEFtcpedNKIReltleiERLKKRLQQLEVVE 650
Cdd:TIGR01612 1059 EIEKEIGK-------------NIELLNKEI--LEEAEINI--------TNF-----NEIK------EKLKHYNFDDFGKE 1104
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 651 GDLmKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAK-----NKAIEKGEAVSQEAELRHRFRMEEAKSRDLQAEVQ 725
Cdd:TIGR01612 1105 ENI-KYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENyideiKAQINDLEDVADKAISNDDPEEIEKKIENIVTKID 1183
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 1270111363 726 AlKEKIHELMNK-EDQLSQLQVDYSVLqqrfmeEETKNKNM 765
Cdd:TIGR01612 1184 K-KKNIYDEIKKlLNEIAEIEKDKTSL------EEVKGINL 1217
|
|
| COG0610 |
COG0610 |
Type I site-specific restriction-modification system, R (restriction) subunit and related ... |
208-428 |
6.39e-03 |
|
Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ... [Defense mechanisms];
Pssm-ID: 440375 [Multi-domain] Cd Length: 936 Bit Score: 41.01 E-value: 6.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 208 RERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKlkaITY 287
Cdd:COG0610 706 TEKLEALDEAVERFLGDEEAR--KEFKKLFKELSRLYNLLSPDDEFGDLELEKYRDDVSFYLALRAKLRKLGEK---LDL 780
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 288 KSKEDR-QKLLKLEVDFEHKASRfsqehEEMNAKLANQEShnrqlrlklvgLSQRIEEL-EETNK---SLQKAEEELQEL 362
Cdd:COG0610 781 KEYEEKiRQLLDEAIDLERKEIK-----PRIKQNPVQYRK-----------FSELLEEIiEEYNNgalDADEVLEELEEL 844
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111363 363 RDKIAKGE--CGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKL 428
Cdd:COG0610 845 AKEVKEEEerAEEEGLNEEELAFYDALAENLGDEKLKELAKELDDLLKKNVTVDWRKRESVRAKLRDA 912
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
141-361 |
6.93e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 39.90 E-value: 6.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 141 EDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNL---LEQERERLKKLLEQ 217
Cdd:pfam00038 35 SELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYEDELNLrtsAENDLVGLRKDLDE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 218 ekAYQARKEKENakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQ----SQKVQDLTQKLREEEEKLKAITYKSKEDr 293
Cdd:pfam00038 115 --ATLARVDLEA--KIESLKEELAFLKKNHEEEVRELQAQVSDTQVNvemdAARKLDLTSALAEIRAQYEEIAAKNREE- 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111363 294 qkllkLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQE 361
Cdd:pfam00038 190 -----AEEWYQSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETEE 252
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
381-512 |
7.90e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.23 E-value: 7.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 381 ESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLE-------VEKLQKRMSELEKLEEAFSRSKSECTqlh 453
Cdd:COG2433 392 EEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEleekderIERLERELSEARSEERREIRKDREIS--- 468
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111363 454 lNLEKEknlTKDLLNELEVVKSRVKELECSESRLEKV-ELSLKDDLT---KLKSFT---VMLVDER 512
Cdd:COG2433 469 -RLDRE---IERLERELEEERERIEELKRKLERLKELwKLEHSGELVpvkVVEKFTkeaIRRLEEE 530
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
266-437 |
9.16e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.14 E-value: 9.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 266 QKVQDLTQKLREEEEKLKAITykskedrqkllklevdfehkasrfsQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEEL 345
Cdd:COG1579 31 AELAELEDELAALEARLEAAK-------------------------TELEDLEKEIKRLELEIEEVEARIKKYEEQLGNV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 346 eETNKSLQKAEEELQELRDKIAKGECGNSSLMAEVESLRKRVLEMEgkdEEITKTEAQCRELKKKLQEEEhhsKELRLEV 425
Cdd:COG1579 86 -RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELE---AELAELEAELEEKKAELDEEL---AELEAEL 158
|
170
....*....|..
gi 1270111363 426 EKLQKRMSELEK 437
Cdd:COG1579 159 EELEAEREELAA 170
|
|
| PRK00106 |
PRK00106 |
ribonuclease Y; |
296-479 |
9.16e-03 |
|
ribonuclease Y;
Pssm-ID: 178867 [Multi-domain] Cd Length: 535 Bit Score: 40.24 E-value: 9.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 296 LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRI-EELEETNKSLQK-----AEEELQELRDKIAKG 369
Cdd:PRK00106 12 LIGLVIGYVLISIKMKSAKEAAELTLLNAEQEAVNLRGKAERDAEHIkKTAKRESKALKKellleAKEEARKYREEIEQE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111363 370 ECGNSSLMAEVES-LRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSRSKSE 448
Cdd:PRK00106 92 FKSERQELKQIESrLTERATSLDRKDENLSSKEKTLESKEQSLTDKSKHIDEREEQVEKLEEQ--KKAELERVAALSQAE 169
|
170 180 190
....*....|....*....|....*....|.
gi 1270111363 449 CTQLHLnLEKEKNLTKDLLNELEVVKSRVKE 479
Cdd:PRK00106 170 AREIIL-AETENKLTHEIATRIREAEREVKD 199
|
|
| |
