![](files/infoQ.gif)
nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform b [Mus musculus]
nucleotidyl transferase family protein( domain architecture ID 117)
nucleotidyl transferase (NT) family protein contains a conserved dinucleotide-binding domain; the NT superfamily includes the class I amino-acyl tRNA synthetases, pantothenate synthetase (PanC), ATP sulfurylase, and cytidylyltransferases
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | ||||
nt_trans super family | cl00015 | nucleotidyl transferase superfamily; nt_trans (nucleotidyl transferase) This superfamily ... |
1-166 | 2.05e-84 | ||||
nucleotidyl transferase superfamily; nt_trans (nucleotidyl transferase) This superfamily includes the class I amino-acyl tRNA synthetases, pantothenate synthetase (PanC), ATP sulfurylase, and the cytidylyltransferases, all of which have a conserved dinucleotide-binding domain. The actual alignment was detected with superfamily member cd09286: Pssm-ID: 469580 [Multi-domain] Cd Length: 225 Bit Score: 247.99 E-value: 2.05e-84
|
||||||||
Name | Accession | Description | Interval | E-value | ||||
NMNAT_Eukarya | cd09286 | Nicotinamide/nicotinate mononucleotide adenylyltransferase, Eukaryotic; Nicotinamide ... |
1-166 | 2.05e-84 | ||||
Nicotinamide/nicotinate mononucleotide adenylyltransferase, Eukaryotic; Nicotinamide/nicotinate mononucleotide (NMN/ NaMN)adenylyltransferase (NMNAT). NMNAT represents the primary bacterial and eukaryotic adenylyltransferases for nicotinamide-nucleotide and for the deamido form, nicotinate nucleotide. It is an indispensable enzyme in the biosynthesis of NAD(+) and NADP(+). Nicotinamide-nucleotide adenylyltransferase synthesizes NAD via the salvage pathway, while nicotinate-nucleotide adenylyltransferase synthesizes the immediate precursor of NAD via the de novo pathway. Human NMNAT displays unique dual substrate specificity toward both NMN and NaMN, and can participate in both de novo and salvage pathways of NAD synthesis. This subfamily consists strictly of eukaryotic members and includes secondary structural elements not found in all NMNATs. Pssm-ID: 185681 [Multi-domain] Cd Length: 225 Bit Score: 247.99 E-value: 2.05e-84
|
||||||||
TIGR00482 | TIGR00482 | nicotinate (nicotinamide) nucleotide adenylyltransferase; This model represents the ... |
1-166 | 2.92e-49 | ||||
nicotinate (nicotinamide) nucleotide adenylyltransferase; This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides] Pssm-ID: 273101 [Multi-domain] Cd Length: 193 Bit Score: 157.87 E-value: 2.92e-49
|
||||||||
PLN02945 | PLN02945 | nicotinamide-nucleotide adenylyltransferase/nicotinate-nucleotide adenylyltransferase |
1-166 | 6.74e-42 | ||||
nicotinamide-nucleotide adenylyltransferase/nicotinate-nucleotide adenylyltransferase Pssm-ID: 178531 [Multi-domain] Cd Length: 236 Bit Score: 140.21 E-value: 6.74e-42
|
||||||||
NadD | COG1057 | Nicotinate-nucleotide adenylyltransferase NadD [Coenzyme transport and metabolism]; ... |
1-166 | 2.22e-27 | ||||
Nicotinate-nucleotide adenylyltransferase NadD [Coenzyme transport and metabolism]; Nicotinate-nucleotide adenylyltransferase NadD is part of the Pathway/BioSystem: NAD biosynthesis Pssm-ID: 440677 [Multi-domain] Cd Length: 197 Bit Score: 101.74 E-value: 2.22e-27
|
||||||||
Name | Accession | Description | Interval | E-value | ||||
NMNAT_Eukarya | cd09286 | Nicotinamide/nicotinate mononucleotide adenylyltransferase, Eukaryotic; Nicotinamide ... |
1-166 | 2.05e-84 | ||||
Nicotinamide/nicotinate mononucleotide adenylyltransferase, Eukaryotic; Nicotinamide/nicotinate mononucleotide (NMN/ NaMN)adenylyltransferase (NMNAT). NMNAT represents the primary bacterial and eukaryotic adenylyltransferases for nicotinamide-nucleotide and for the deamido form, nicotinate nucleotide. It is an indispensable enzyme in the biosynthesis of NAD(+) and NADP(+). Nicotinamide-nucleotide adenylyltransferase synthesizes NAD via the salvage pathway, while nicotinate-nucleotide adenylyltransferase synthesizes the immediate precursor of NAD via the de novo pathway. Human NMNAT displays unique dual substrate specificity toward both NMN and NaMN, and can participate in both de novo and salvage pathways of NAD synthesis. This subfamily consists strictly of eukaryotic members and includes secondary structural elements not found in all NMNATs. Pssm-ID: 185681 [Multi-domain] Cd Length: 225 Bit Score: 247.99 E-value: 2.05e-84
|
||||||||
TIGR00482 | TIGR00482 | nicotinate (nicotinamide) nucleotide adenylyltransferase; This model represents the ... |
1-166 | 2.92e-49 | ||||
nicotinate (nicotinamide) nucleotide adenylyltransferase; This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides] Pssm-ID: 273101 [Multi-domain] Cd Length: 193 Bit Score: 157.87 E-value: 2.92e-49
|
||||||||
PLN02945 | PLN02945 | nicotinamide-nucleotide adenylyltransferase/nicotinate-nucleotide adenylyltransferase |
1-166 | 6.74e-42 | ||||
nicotinamide-nucleotide adenylyltransferase/nicotinate-nucleotide adenylyltransferase Pssm-ID: 178531 [Multi-domain] Cd Length: 236 Bit Score: 140.21 E-value: 6.74e-42
|
||||||||
NadD | COG1057 | Nicotinate-nucleotide adenylyltransferase NadD [Coenzyme transport and metabolism]; ... |
1-166 | 2.22e-27 | ||||
Nicotinate-nucleotide adenylyltransferase NadD [Coenzyme transport and metabolism]; Nicotinate-nucleotide adenylyltransferase NadD is part of the Pathway/BioSystem: NAD biosynthesis Pssm-ID: 440677 [Multi-domain] Cd Length: 197 Bit Score: 101.74 E-value: 2.22e-27
|
||||||||
nadD | PRK00071 | nicotinate-nucleotide adenylyltransferase; |
1-166 | 1.24e-18 | ||||
nicotinate-nucleotide adenylyltransferase; Pssm-ID: 234611 [Multi-domain] Cd Length: 203 Bit Score: 79.11 E-value: 1.24e-18
|
||||||||
NMNAT | cd02165 | Nicotinamide/nicotinate mononucleotide adenylyltransferase; Nicotinamide/nicotinate ... |
1-166 | 2.04e-18 | ||||
Nicotinamide/nicotinate mononucleotide adenylyltransferase; Nicotinamide/nicotinate mononucleotide (NMN/ NaMN)adenylyltransferase (NMNAT). NMNAT represents the primary bacterial and eukaryotic adenylyltransferases for nicotinamide-nucleotide and for the deamido form, nicotinate nucleotide. It is an indispensable enzyme in the biosynthesis of NAD(+) and NADP(+). Nicotinamide-nucleotide adenylyltransferase synthesizes NAD via the salvage pathway, while nicotinate-nucleotide adenylyltransferase synthesizes the immediate precursor of NAD via the de novo pathway. Human NMNAT displays unique dual substrate specificity toward both NMN and NaMN, and can participate in both de novo and salvage pathways of NAD synthesis. Pssm-ID: 185680 [Multi-domain] Cd Length: 192 Bit Score: 78.44 E-value: 2.04e-18
|
||||||||
Blast search parameters | ||||
|