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vacuolar protein sorting-associated protein 37A isoform 5 [Homo sapiens]
vacuolar protein sorting family 37 protein( domain architecture ID 12073684)
vacuolar protein sorting family 37 protein similar to vacuolar protein sorting-associated protein 37 (Vps37), which is a component of the ESCRT-I complex, a regulator of vesicular trafficking process
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Mod_r | pfam07200 | Modifier of rudimentary (Mod(r)) protein; This family represents a conserved region ... |
145-284 | 5.72e-44 | |||
Modifier of rudimentary (Mod(r)) protein; This family represents a conserved region approximately 150 residues long within a number of eukaryotic proteins that show homology with Drosophila melanogaster Modifier of rudimentary (Mod(r)) proteins. The N-terminal half of Mod(r) proteins is acidic, whereas the C-terminal half is basic, and both of these regions are represented in this family. Members of this family include the Vps37 subunit of the endosomal sorting complex ESCRT-I, a complex involved in recruiting transport machinery for protein sorting at the multivesicular body (MVB). The yeast ESCRT-I complex consists of three proteins (Vps23, Vps28 and Vps37). The mammalian homolog of Vps37 interacts with Tsg101 (Pfam: PF05743) through its mod(r) domain and its function is essential for lysosomal sorting of EGF receptors. : Pssm-ID: 462117 [Multi-domain] Cd Length: 146 Bit Score: 147.00 E-value: 5.72e-44
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Name | Accession | Description | Interval | E-value | |||
Mod_r | pfam07200 | Modifier of rudimentary (Mod(r)) protein; This family represents a conserved region ... |
145-284 | 5.72e-44 | |||
Modifier of rudimentary (Mod(r)) protein; This family represents a conserved region approximately 150 residues long within a number of eukaryotic proteins that show homology with Drosophila melanogaster Modifier of rudimentary (Mod(r)) proteins. The N-terminal half of Mod(r) proteins is acidic, whereas the C-terminal half is basic, and both of these regions are represented in this family. Members of this family include the Vps37 subunit of the endosomal sorting complex ESCRT-I, a complex involved in recruiting transport machinery for protein sorting at the multivesicular body (MVB). The yeast ESCRT-I complex consists of three proteins (Vps23, Vps28 and Vps37). The mammalian homolog of Vps37 interacts with Tsg101 (Pfam: PF05743) through its mod(r) domain and its function is essential for lysosomal sorting of EGF receptors. Pssm-ID: 462117 [Multi-domain] Cd Length: 146 Bit Score: 147.00 E-value: 5.72e-44
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Name | Accession | Description | Interval | E-value | |||
Mod_r | pfam07200 | Modifier of rudimentary (Mod(r)) protein; This family represents a conserved region ... |
145-284 | 5.72e-44 | |||
Modifier of rudimentary (Mod(r)) protein; This family represents a conserved region approximately 150 residues long within a number of eukaryotic proteins that show homology with Drosophila melanogaster Modifier of rudimentary (Mod(r)) proteins. The N-terminal half of Mod(r) proteins is acidic, whereas the C-terminal half is basic, and both of these regions are represented in this family. Members of this family include the Vps37 subunit of the endosomal sorting complex ESCRT-I, a complex involved in recruiting transport machinery for protein sorting at the multivesicular body (MVB). The yeast ESCRT-I complex consists of three proteins (Vps23, Vps28 and Vps37). The mammalian homolog of Vps37 interacts with Tsg101 (Pfam: PF05743) through its mod(r) domain and its function is essential for lysosomal sorting of EGF receptors. Pssm-ID: 462117 [Multi-domain] Cd Length: 146 Bit Score: 147.00 E-value: 5.72e-44
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Blast search parameters | ||||
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