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Conserved domains on  [gi|1393169995|ref|NP_001350664|]
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transmembrane emp24 domain-containing protein 3 isoform d precursor [Homo sapiens]

Protein Classification

emp24/gp25L/p24 family protein( domain architecture ID 10471359)

emp24/gp25L/p24 family protein such as various transmembrane emp24 domain-containing proteins, which are involved in vesicular protein trafficking

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
EMP24_GP25L pfam01105
emp24/gp25L/p24 family/GOLD; Members of this family are implicated in bringing cargo forward ...
 28-130 1.88e-34

emp24/gp25L/p24 family/GOLD; Members of this family are implicated in bringing cargo forward from the ER and binding to coat proteins by their cytoplasmic domains. This domain corresponds closely to the beta-strand rich GOLD domain described in. The GOLD domain is always found combined with lipid- or membrane-association domains.


:

Pssm-ID: 426051  Cd Length: 181  Bit Score: 118.17  E-value: 1.88e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393169995  28 ELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDP--QGNTIY-RETKKQYDSFTYRAEVKGVYQFCFSN 104
Cdd:pfam01105   1 ALTFELPAGEKECFYEEVPKGTLVTGSYQVISGGGLDVDFTVTDPdgNGNVIYsKKDRKSGGDFSFTATESGEYKFCFDN 80

                          90       100
                  ....*....|....*....|....*.
gi 1393169995 105 EFSTFSHKTVYFDFQVGDEPPILPDM 130
Cdd:pfam01105  81 SFSTFSSKTVSFDIKVGSEAKDYDDV 106
 
Name Accession Description Interval E-value
EMP24_GP25L pfam01105
emp24/gp25L/p24 family/GOLD; Members of this family are implicated in bringing cargo forward ...
 28-130 1.88e-34

emp24/gp25L/p24 family/GOLD; Members of this family are implicated in bringing cargo forward from the ER and binding to coat proteins by their cytoplasmic domains. This domain corresponds closely to the beta-strand rich GOLD domain described in. The GOLD domain is always found combined with lipid- or membrane-association domains.


Pssm-ID: 426051  Cd Length: 181  Bit Score: 118.17  E-value: 1.88e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393169995  28 ELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDP--QGNTIY-RETKKQYDSFTYRAEVKGVYQFCFSN 104
Cdd:pfam01105   1 ALTFELPAGEKECFYEEVPKGTLVTGSYQVISGGGLDVDFTVTDPdgNGNVIYsKKDRKSGGDFSFTATESGEYKFCFDN 80

                          90       100
                  ....*....|....*....|....*.
gi 1393169995 105 EFSTFSHKTVYFDFQVGDEPPILPDM 130
Cdd:pfam01105  81 SFSTFSSKTVSFDIKVGSEAKDYDDV 106
 
Name Accession Description Interval E-value
EMP24_GP25L pfam01105
emp24/gp25L/p24 family/GOLD; Members of this family are implicated in bringing cargo forward ...
 28-130 1.88e-34

emp24/gp25L/p24 family/GOLD; Members of this family are implicated in bringing cargo forward from the ER and binding to coat proteins by their cytoplasmic domains. This domain corresponds closely to the beta-strand rich GOLD domain described in. The GOLD domain is always found combined with lipid- or membrane-association domains.


Pssm-ID: 426051  Cd Length: 181  Bit Score: 118.17  E-value: 1.88e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393169995  28 ELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDP--QGNTIY-RETKKQYDSFTYRAEVKGVYQFCFSN 104
Cdd:pfam01105   1 ALTFELPAGEKECFYEEVPKGTLVTGSYQVISGGGLDVDFTVTDPdgNGNVIYsKKDRKSGGDFSFTATESGEYKFCFDN 80

                          90       100
                  ....*....|....*....|....*.
gi 1393169995 105 EFSTFSHKTVYFDFQVGDEPPILPDM 130
Cdd:pfam01105  81 SFSTFSSKTVSFDIKVGSEAKDYDDV 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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