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Conserved domains on  [gi|1393901873|ref|NP_001350819|]
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protein jagunal homolog 1 isoform b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jagunal super family cl06218
Jagunal, ER re-organization during oogenesis; Jagunal is an endoplasmic-reticulum (ER) ...
 1-123 6.53e-48

Jagunal, ER re-organization during oogenesis; Jagunal is an endoplasmic-reticulum (ER)-membrane protein found in eukaryotes. It is involved in reorganizing the ER in cells that must increase exocytic membrane traffic during development, that is, in the oocyte during vitellogenesis. It facilitates vesicular traffic in the subcortex.


The actual alignment was detected with superfamily member pfam07086:

Pssm-ID: 462086  Cd Length: 186  Bit Score: 152.03  E-value: 6.53e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393901873   1 MSVGHLRLL-------SHDQVAMPYQWEYPYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQ 73
Cdd:pfam07086  55 LSVDILDRLdifileiEELQIPQPLLWEYIWCLSIIPSFLGLSALKKNKISLMKLYMIGIGLFGIGPLIYGAMYYFPDVW 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1393901873  74 QLYRHGKAYR--FLFGFSAVSIMYLVLVLAVQVHAWQLYYSKKLLDSWFTST 123
Cdd:pfam07086 135 QYLRHGKASRthLWFGFPYVVLWYIFLVIAVQVHAFSLYFSWKLLKAWKTRG 186
 
Name Accession Description Interval E-value
Jagunal pfam07086
Jagunal, ER re-organization during oogenesis; Jagunal is an endoplasmic-reticulum (ER) ...
 1-123 6.53e-48

Jagunal, ER re-organization during oogenesis; Jagunal is an endoplasmic-reticulum (ER)-membrane protein found in eukaryotes. It is involved in reorganizing the ER in cells that must increase exocytic membrane traffic during development, that is, in the oocyte during vitellogenesis. It facilitates vesicular traffic in the subcortex.


Pssm-ID: 462086  Cd Length: 186  Bit Score: 152.03  E-value: 6.53e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393901873   1 MSVGHLRLL-------SHDQVAMPYQWEYPYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQ 73
Cdd:pfam07086  55 LSVDILDRLdifileiEELQIPQPLLWEYIWCLSIIPSFLGLSALKKNKISLMKLYMIGIGLFGIGPLIYGAMYYFPDVW 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1393901873  74 QLYRHGKAYR--FLFGFSAVSIMYLVLVLAVQVHAWQLYYSKKLLDSWFTST 123
Cdd:pfam07086 135 QYLRHGKASRthLWFGFPYVVLWYIFLVIAVQVHAFSLYFSWKLLKAWKTRG 186
 
Name Accession Description Interval E-value
Jagunal pfam07086
Jagunal, ER re-organization during oogenesis; Jagunal is an endoplasmic-reticulum (ER) ...
 1-123 6.53e-48

Jagunal, ER re-organization during oogenesis; Jagunal is an endoplasmic-reticulum (ER)-membrane protein found in eukaryotes. It is involved in reorganizing the ER in cells that must increase exocytic membrane traffic during development, that is, in the oocyte during vitellogenesis. It facilitates vesicular traffic in the subcortex.


Pssm-ID: 462086  Cd Length: 186  Bit Score: 152.03  E-value: 6.53e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393901873   1 MSVGHLRLL-------SHDQVAMPYQWEYPYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQ 73
Cdd:pfam07086  55 LSVDILDRLdifileiEELQIPQPLLWEYIWCLSIIPSFLGLSALKKNKISLMKLYMIGIGLFGIGPLIYGAMYYFPDVW 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1393901873  74 QLYRHGKAYR--FLFGFSAVSIMYLVLVLAVQVHAWQLYYSKKLLDSWFTST 123
Cdd:pfam07086 135 QYLRHGKASRthLWFGFPYVVLWYIFLVIAVQVHAFSLYFSWKLLKAWKTRG 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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