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Conserved domains on  [gi|1463570027|ref|NP_001352345|]
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myocardin-related transcription factor B isoform 8 [Homo sapiens]

Protein Classification

RPEL repeat-containing protein( domain architecture ID 10499653)

RPEL repeat-containing protein such as Phactrs 1-4, a family of protein phosphatase 1 and actin regulatory proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
68-93 3.00e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.85  E-value: 3.00e-06
                           10        20
                   ....*....|....*....|....*.
gi 1463570027   68 DDLNEKIAQRPGPMELVEKNILPVDS 93
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 126-250 5.89e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 5.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1463570027  126 PDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEflkTPPTADQP--PPRPAAPVLPTNTV-SSAKPGP 202
Cdd:PHA03247  2784 TRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL---PPPTSAQPtaPPPPPGPPPPSLPLgGSVAPGG 2860

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1463570027  203 ALVK----QSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQ 250
Cdd:PHA03247  2861 DVRRrppsRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQ 2912
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 25-48 6.43e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


:

Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.18  E-value: 6.43e-05
                          10        20
                  ....*....|....*....|....
gi 1463570027  25 FLKHKIRSRPDRSELVRMHILEET 48
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
68-93 3.00e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.85  E-value: 3.00e-06
                           10        20
                   ....*....|....*....|....*.
gi 1463570027   68 DDLNEKIAQRPGPMELVEKNILPVDS 93
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 69-92 1.23e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 41.11  E-value: 1.23e-05
                          10        20
                  ....*....|....*....|....
gi 1463570027  69 DLNEKIAQRPGPMELVEKNILPVD 92
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
PHA03247 PHA03247
large tegument protein UL36; Provisional
 126-250 5.89e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 5.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1463570027  126 PDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEflkTPPTADQP--PPRPAAPVLPTNTV-SSAKPGP 202
Cdd:PHA03247  2784 TRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL---PPPTSAQPtaPPPPPGPPPPSLPLgGSVAPGG 2860

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1463570027  203 ALVK----QSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQ 250
Cdd:PHA03247  2861 DVRRrppsRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQ 2912
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 25-48 6.43e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.18  E-value: 6.43e-05
                          10        20
                  ....*....|....*....|....
gi 1463570027  25 FLKHKIRSRPDRSELVRMHILEET 48
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
25-48 7.29e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 36.30  E-value: 7.29e-04
                           10        20
                   ....*....|....*....|....
gi 1463570027   25 FLKHKIRSRPDRSELVRMHILEET 48
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKEL 25
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
68-93 3.00e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.85  E-value: 3.00e-06
                           10        20
                   ....*....|....*....|....*.
gi 1463570027   68 DDLNEKIAQRPGPMELVEKNILPVDS 93
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 69-92 1.23e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 41.11  E-value: 1.23e-05
                          10        20
                  ....*....|....*....|....
gi 1463570027  69 DLNEKIAQRPGPMELVEKNILPVD 92
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
PHA03247 PHA03247
large tegument protein UL36; Provisional
 126-250 5.89e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 5.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1463570027  126 PDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEflkTPPTADQP--PPRPAAPVLPTNTV-SSAKPGP 202
Cdd:PHA03247  2784 TRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL---PPPTSAQPtaPPPPPGPPPPSLPLgGSVAPGG 2860

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1463570027  203 ALVK----QSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQ 250
Cdd:PHA03247  2861 DVRRrppsRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQ 2912
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 25-48 6.43e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.18  E-value: 6.43e-05
                          10        20
                  ....*....|....*....|....
gi 1463570027  25 FLKHKIRSRPDRSELVRMHILEET 48
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
114-252 1.75e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.84  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1463570027 114 FSFDEDSSDALSPDQPASQESQGSAASPSEP-KVSESPSPVTTNTPAQfASVSPTVPEFLKTPPTADQPPPRPaAPVLPT 192
Cdd:PRK14971  363 TQKGDDASGGRGPKQHIKPVFTQPAAAPQPSaAAAASPSPSQSSAAAQ-PSAPQSATQPAGTPPTVSVDPPAA-VPVNPP 440

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1463570027 193 NTVSSAKPGPalVKQSHPKNPNDKHRS-----KKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQMD 252
Cdd:PRK14971  441 STAPQAVRPA--QFKEEKKIPVSKVSSlgpstLRPIQEKAEQATGNIKEAPTGTQKEIFTEEDLQ 503
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
25-48 7.29e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 36.30  E-value: 7.29e-04
                           10        20
                   ....*....|....*....|....
gi 1463570027   25 FLKHKIRSRPDRSELVRMHILEET 48
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKEL 25
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 122-224 6.97e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 38.13  E-value: 6.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1463570027 122 DALSPDQPASQESQGSAASPSEPKVSESPS-PVTTNTPAqfasvSPTVPEFLKTPPTAdQPPPRPAAPVLPTNTVSSAKP 200
Cdd:PTZ00449  584 DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKlPELLDIPK-----SPKRPESPKSPKRP-PPPQRPSSPERPEGPKIIKSP 657

                          90       100
                  ....*....|....*....|....
gi 1463570027 201 GPAlvkqSHPKNPNDKHRSKKCKD 224
Cdd:PTZ00449  658 KPP----KSPKPPFDPKFKEKFYD 677
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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