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Conserved domains on  [gi|1761178578|ref|NP_001361701|]
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tetratricopeptide repeat protein 23-like isoform 2 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-403 3.96e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 3.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 107 AQALANLAYGYLTlRGLPAQAKKHAEKARNtlltwkrnttSDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKAE 186
Cdd:COG2956    42 VEAHLALGNLYRR-RGEYDRAIRIHQKLLE----------RDPDRAEALLELAQDYLKAG--------------LLDRAE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 187 RNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNH 266
Cdd:COG2956    97 ELLEKLLELDPDDA--------EALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 267 KQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWL 346
Cdd:COG2956   161 DEAIEALEKAL--------KLDPDCARALLLLAELYLEQG--DYEEAIAA--------LERALEQDPDYLPALPRLAELY 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1761178578 347 IENGEKQEAYRLLKSTLNSGNFgdcgkkvAETFYNMGSICFAKGELGEAIELLSKCL 403
Cdd:COG2956   223 EKLGDPEEALELLRKALELDPS-------DDLLLALADLLERKEGLEAALALLERQL 272
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-403 3.96e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 3.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 107 AQALANLAYGYLTlRGLPAQAKKHAEKARNtlltwkrnttSDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKAE 186
Cdd:COG2956    42 VEAHLALGNLYRR-RGEYDRAIRIHQKLLE----------RDPDRAEALLELAQDYLKAG--------------LLDRAE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 187 RNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNH 266
Cdd:COG2956    97 ELLEKLLELDPDDA--------EALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 267 KQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWL 346
Cdd:COG2956   161 DEAIEALEKAL--------KLDPDCARALLLLAELYLEQG--DYEEAIAA--------LERALEQDPDYLPALPRLAELY 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1761178578 347 IENGEKQEAYRLLKSTLNSGNFgdcgkkvAETFYNMGSICFAKGELGEAIELLSKCL 403
Cdd:COG2956   223 EKLGDPEEALELLRKALELDPS-------DDLLLALADLLERKEGLEAALALLERQL 272
TPR_12 pfam13424
Tetratricopeptide repeat;
248-317 1.22e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 1.22e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 248 ELISLYEEIAQIEQLRKNHKQAIQYLQQAYSICVSSFSEVSPQTAEASALLAKAYAMSGasEYRDAVEIY 317
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELG--RYEEALELL 68
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 232-317 9.83e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 41.33  E-value: 9.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 232 EKAIcDVI-----LDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSicvssfseVSPQTAEASALLAKAYAMSG 306
Cdd:PRK11788  158 QKAI-DVAerlekLGGDSLRVEIAHFYCELAQQALARGDLDAARALLKKALA--------ADPQCVRASILLGDLALAQG 228

                          90
                  ....*....|.
gi 1761178578 307 asEYRDAVEIY 317
Cdd:PRK11788  229 --DYAAAIEAL 237
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-403 3.96e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 3.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 107 AQALANLAYGYLTlRGLPAQAKKHAEKARNtlltwkrnttSDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKAE 186
Cdd:COG2956    42 VEAHLALGNLYRR-RGEYDRAIRIHQKLLE----------RDPDRAEALLELAQDYLKAG--------------LLDRAE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 187 RNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNH 266
Cdd:COG2956    97 ELLEKLLELDPDDA--------EALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 267 KQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWL 346
Cdd:COG2956   161 DEAIEALEKAL--------KLDPDCARALLLLAELYLEQG--DYEEAIAA--------LERALEQDPDYLPALPRLAELY 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1761178578 347 IENGEKQEAYRLLKSTLNSGNFgdcgkkvAETFYNMGSICFAKGELGEAIELLSKCL 403
Cdd:COG2956   223 EKLGDPEEALELLRKALELDPS-------DDLLLALADLLERKEGLEAALALLERQL 272
TPR_12 pfam13424
Tetratricopeptide repeat;
248-317 1.22e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 1.22e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 248 ELISLYEEIAQIEQLRKNHKQAIQYLQQAYSICVSSFSEVSPQTAEASALLAKAYAMSGasEYRDAVEIY 317
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELG--RYEEALELL 68
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 162-403 4.61e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 4.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 162 YYTLGVAWLLQNHGKQAYIHLQKAErnmkelkELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvild 241
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEAL-------ELDPETV--------EAHLALGNLYRRRGEYDRAIRIHQKLL------ 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 242 kgHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAysicvssfSEVSPQTAEASALLAKAYAMSGasEYRDAVEIYfiRS 321
Cdd:COG2956    70 --ERDPDRAEALLELAQDYLKAGLLDRAEELLEKL--------LELDPDDAEALRLLAEIYEQEG--DWEKAIEVL--ER 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 322 ISTYQTLGSEDYETLTAIedfctwLIENGEKQEAYRLLKSTLNSgnfgdcGKKVAETFYNMGSICFAKGELGEAIELLSK 401
Cdd:COG2956   136 LLKLGPENAHAYCELAEL------YLEQGDYDEAIEALEKALKL------DPDCARALLLLAELYLEQGDYEEAIAALER 203


                  ..
gi 1761178578 402 CL 403
Cdd:COG2956   204 AL 205
COG3899 COG3899
Predicted ATPase [General function prediction only];
240-405 1.30e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.46  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578  240 LDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSICvssfSEVSPQTAEASALLAKAYAMSGASEYRDAVEIY-F 318
Cdd:COG3899    695 LNRAGERDRAARLLLRAARRALARGAYAEALRYLERALELL----PPDPEEEYRLALLLELAEALYLAGRFEEAEALLeR 770

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578  319 IRSISTYQTLGSEDYETLTAIEDFCTWL--IENGEKQEAYRLLKSTLNSGNFGDCGKKVAETFYNMGSICFAKGELGEAI 396
Cdd:COG3899    771 ALAARALAALAALRHGNPPASARAYANLglLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREAL 850


                   ....*....
gi 1761178578  397 ELLSKCLMI 405
Cdd:COG3899    851 ELLREALEA 859
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 214-317 6.06e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.60  E-value: 6.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 214 LGRASLAMHRMNLALAYFEKAICdviLDKGHntselISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAE 293
Cdd:COG4235    23 LGRAYLRLGRYDEALAAYEKALR---LDPDN-----ADALLDLAEALLAAGDTEEAEELLERALAL--------DPDNPE 86

                          90       100
                  ....*....|....*....|....
gi 1761178578 294 ASALLAKAYAMSGasEYRDAVEIY 317
Cdd:COG4235    87 ALYLLGLAAFQQG--DYAEAIAAW 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
107-317 7.36e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 7.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 107 AQALANLAYGYLTLrGLPAQAKKHAEKARntlltwkrnttsdkdkkEILETLVRLYYTLGVAWLLQNHGKQAYIHLQKA- 185
Cdd:COG0457     8 AEAYNNLGLAYRRL-GRYEEAIEDYEKAL-----------------ELDPDDAEALYNLGLAYLRLGRYEEALADYEQAl 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 186 ERNMKELKELNNgnicgiqvsekdltiaLGRASLAMHRMNLALAYFEKAIcdvILDkghntSELISLYEEIAQIEQLRKN 265
Cdd:COG0457    70 ELDPDDAEALNN----------------LGLALQALGRYEEALEDYDKAL---ELD-----PDDAEALYNLGLALLELGR 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1761178578 266 HKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGasEYRDAVEIY 317
Cdd:COG0457   126 YDEAIEAYERALEL--------DPDDADALYNLGIALEKLG--RYEEALELL 167
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 106-315 8.35e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 8.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 106 CAQALANLAYGYLTLRGLPAQAKKHAEKARntlltwkrnttsdkdkkEILETLVRLYYTLGVAWLLQNHGKQAYIHLQKA 185
Cdd:COG3914    76 LLAALLELAALLLQALGRYEEALALYRRAL-----------------ALNPDNAEALFNLGNLLLALGRLEEALAALRRA 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 186 ErnmkelkELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAICdviLDKGHntselISLYEEIAQIEQLRKN 265
Cdd:COG3914   139 L-------ALNPDFA--------EAYLNLGEALRRLGRLEEAIAALRRALE---LDPDN-----AEALNNLGNALQDLGR 195

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1761178578 266 HKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGASEYRDAVE 315
Cdd:COG3914   196 LEEAIAAYRRALEL--------DPDNADAHSNLLFALRQACDWEVYDRFE 237
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 232-317 9.83e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 41.33  E-value: 9.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 232 EKAIcDVI-----LDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSicvssfseVSPQTAEASALLAKAYAMSG 306
Cdd:PRK11788  158 QKAI-DVAerlekLGGDSLRVEIAHFYCELAQQALARGDLDAARALLKKALA--------ADPQCVRASILLGDLALAQG 228

                          90
                  ....*....|.
gi 1761178578 307 asEYRDAVEIY 317
Cdd:PRK11788  229 --DYAAAIEAL 237
TPR_12 pfam13424
Tetratricopeptide repeat;
214-279 1.33e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.37  E-value: 1.33e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1761178578 214 LGRASLAMHRMNLALAYFEKAICDVILDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSI 279
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 214-401 1.35e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.48  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 214 LGRASLAMHRMNLALAY-----FEKAIcDVILDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYsicvssfsEVS 288
Cdd:COG2956     2 LLPVAAALGWYFKGLNYllngqPDKAI-DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLL--------ERD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 289 PQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWLIENGEKQEAYRLLKSTLNSgnf 368
Cdd:COG2956    73 PDRAEALLELAQDYLKAG--LLDRAEEL--------LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL--- 139

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1761178578 369 gdcGKKVAETFYNMGSICFAKGELGEAIELLSK 401
Cdd:COG2956   140 ---GPENAHAYCELAELYLEQGDYDEAIEALEK 169
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
253-406 3.14e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 253 YEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGasEYRDAVEiYFIRSIStyqtLGSED 332
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLG--RYEEALA-DYEQALE----LDPDD 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1761178578 333 YETLTAIEdfcTWLIENGEKQEAYRLLKSTLnsgnfgDCGKKVAETFYNMGSICFAKGELGEAIELLSKCLMIQ 406
Cdd:COG0457    76 AEALNNLG---LALQALGRYEEALEDYDKAL------ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
158-317 4.01e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.83  E-value: 4.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 158 LVRLYYTLGVAWLLQNHGKQAYIHLQKA-ERNMKELKELNNgnicgiqvsekdltiaLGRASLAMHRMNLALAYFEKAIc 236
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKAlELDPDDAEALYN----------------LGLAYLRLGRYEEALADYEQAL- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 237 dvildkgHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGasEYRDAVEI 316
Cdd:COG0457    70 -------ELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDDAEALYNLGLALLELG--RYDEAIEA 132


                  .
gi 1761178578 317 Y 317
Cdd:COG0457   133 Y 133
TPR_12 pfam13424
Tetratricopeptide repeat;
375-430 4.19e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.21  E-value: 4.19e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1761178578 375 VAETFYNMGSICFAKGELGEAIELLSKCLMIQSLVYGSEHIKSIETKSLLSLLQRA 430
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLE 57
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 106-276 5.06e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.09  E-value: 5.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 106 CAQALANLAYGYLtLRGLPAQAKKHAEKARNTlltwkrnttsDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKA 185
Cdd:COG4783     3 CAEALYALAQALL-LAGDYDEAEALLEKALEL----------DPDNPEAFALLGEILLQLG--------------DLDEA 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 186 ERNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvILDKGHntselISLYEEIAQIEQLRKN 265
Cdd:COG4783    58 IVLLHEALELDPDEP--------EARLNLGLALLKAGDYDEALALLEKAL---KLDPEH-----PEAYLRLARAYRALGR 121

                         170
                  ....*....|.
gi 1761178578 266 HKQAIQYLQQA 276
Cdd:COG4783   122 PDEAIAALEKA 132
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
214-401 5.25e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.45  E-value: 5.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 214 LGRASLAMHRMNLALAYFEKAIcdvILDKGHntselISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAE 293
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKAL---ELDPDD-----AEALYNLGLAYLRLGRYEEALADYEQALEL--------DPDDAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1761178578 294 ASALLAKAYAMSGasEYRDAVEiYFIRSIStyqtLGSEDYETLTAIEDFctwLIENGEKQEAYRLLKSTLnsgnfgDCGK 373
Cdd:COG0457    78 ALNNLGLALQALG--RYEEALE-DYDKALE----LDPDDAEALYNLGLA---LLELGRYDEAIEAYERAL------ELDP 141

                         170       180
                  ....*....|....*....|....*...
gi 1761178578 374 KVAETFYNMGSICFAKGELGEAIELLSK 401
Cdd:COG0457   142 DDADALYNLGIALEKLGRYEEALELLEK 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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